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Relevant bibliographies by topics / Activité antiplasmodiale

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Journal articles

Academic literature on the topic 'Activité antiplasmodiale'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 May 2024

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Journal articles on the topic "Activité antiplasmodiale"

1

Kopa, Théodora K., Pierre Tane, Hippolyte K. Wabo, et al. "Activité antiplasmodiale in vitro des composés isolés des écorces du tronc de Vitex thyrsiflora." Comptes Rendus Chimie 19, no. 7 (2016): 807–11. http://dx.doi.org/10.1016/j.crci.2015.10.007.

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2

Gopalan, Sivaperumal, Kannnan Kulanthai, Gnanavel Sadashivam, Perumal Pachiappan, Sowmiya Rajamani, and Deepak Paramasivam. "Extraction, isolation, characterization, semi-synthesis and antiplasmodial activity of Justicia adathoda leaves." Bangladesh Journal of Pharmacology 11, no. 4 (2016): 878. http://dx.doi.org/10.3329/bjp.v11i4.28569.

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<p>There is a need to investigate the new sources of antimalarial drugs which are more effective against Plasmodium falciparum. The present study was undertaken to evaluate the in vitro antiplasmodial activity of vasicinone, vasicine and 9-oxo-1, 2, 3, 9-tetrahydropyrrolo [2,1-b]quinazolin-3-yl acetate (VA-1). Vasicinone and vasicine were extracted from the leaves of Justicia adhatoda. The novel compound VA-1 was synthesized from alkaloid the alkaloid vasicine, which was isolated from the ethanol extract of J. adhatoda leaves. Vasicine (IC<sub>50</sub> = 89.8 µg/mL) and vasic

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3

Rifaldi, Arif Fadlan, Taslim Ersam, Adi Setyo Purnomo, and Sri Fatmawati. "Antiplasmodial and Antioxidant Activity of Garcinia Bancana Extract." Journal of Hunan University Natural Sciences 50, no. 1 (2023): 278–88. http://dx.doi.org/10.55463/issn.1674-2974.50.1.28.

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Malaria caused by Plasmodium parasites is a significant public health issue, particularly in tropical and subtropical regions. There is also resistance to chloroquine-based therapy, which highlights the need for novel therapeutic agents. Therefore, our project in exploring antiplasmodial agents from Garcinia Indonesia continues. This study evaluates the phytochemical content of G. bancana by the total phenolic content (TPC) and total flavonoid content (TFC) and its in vitro antioxidant and antiplasmodial activities. The TPC and TFC values were determined using a UV-VIS spectrophotometer, while

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4

Zakiah, Mistika, Rul Afiyah Syarif, Mustofa Mustofa, Jumina Jumina, Nela Fatmasari, and Eti Nurwening Sholikhah. "In Vitro Antiplasmodial, Heme Polymerization, and Cytotoxicity of Hydroxyxanthone Derivatives." Journal of Tropical Medicine 2021 (March 31, 2021): 1–11. http://dx.doi.org/10.1155/2021/8866681.

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The previous study showed that xanthone had antiplasmodial activity. Xanthone, with additional hydroxyl groups, was synthesized to increase its antiplasmodial activity. One of the strategies to evaluate a compound that can be developed into an antimalarial drug is by testing its mechanism in inhibiting heme polymerization. In acidic condition, hematin can be polymerized to β-hematin in vitro, which is analog with hemozoin in Plasmodium. This study was conducted to evaluate the antiplasmodial activity of hydroxyxanthone derivative compounds on two strains of Plasmodium falciparum 3D-7 and FCR-3

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5

Okokon, Jude E., Basil Ita, and Aniekan E. Udokpoh. "Antiplasmodial activity ofHomalium letestui." Phytotherapy Research 20, no. 11 (2006): 949–51. http://dx.doi.org/10.1002/ptr.1983.

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6

Okokon, Jude E., Peace M. E. Ubulom, and Aniekan E. Udokpoh. "Antiplasmodial activity ofSetaria megaphylla." Phytotherapy Research 21, no. 4 (2007): 366–68. http://dx.doi.org/10.1002/ptr.2059.

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7

Tshibangu, Pascal Tshisekedi. "Antiplasmodial Activity of Griffipavixanthone and Morelloflavone the Main Compounds from Garcinia Chromocarpa Engl. (Clusiaceae)." International Journal of Pharmacognosy & Chinese Medicine 6, no. 1 (2022): 1–7. http://dx.doi.org/10.23880/ipcm-16000225.

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Ethnopharmacological relevance: The genus Garcinia is a rich source of species mostly used in traditional medicine to treat a many diseases. Bioactive constituents from this genus have been used as antimicrobial, anticancer, antimalarial, anti-inflammatory, hepatoprotective and anti-HIV. According to these properties, major compounds of this plant have been evaluated for their antiplasmodial activity. Materials and methods: The methanol extract of the G. chromocarpa stem bark was used in this study. The chromatographic fractionation of this latest led to the isolation of two major compounds, i

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8

Grace, Mary H., Carmen Lategan, Rocky Graziose, Peter J. Smith, Ilya Raskin, and Mary Ann Lila. "Antiplasmodial Activity of the Ethnobotanical Plant Cassia fistula." Natural Product Communications 7, no. 10 (2012): 1934578X1200701. http://dx.doi.org/10.1177/1934578x1200701002.

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In our ongoing investigation of new compounds with activity against malaria parasites, we tested the in vitro antiplasmodial activity of fractions and purified compounds from Cassia fistula L., a plant traditionally used by native populations of Tanzania, Zimbabwe, Mozambique and Brazil to treat malaria or symptoms associated with this disease. Crude extracts from leaves, bark and fruits were tested for their antiplasmodial activity against the chloroquine-sensitive strain of Plasmodium falciparum(D10), where leaf extracts showed the highest activity. The chloroform extract of the leaves was f

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9

Hermann, Theresa, Patrick Hochegger, Johanna Dolensky, et al. "Synthesis and Structure-Activity Relationships of New 2-Phenoxybenzamides with Antiplasmodial Activity." Pharmaceuticals 14, no. 11 (2021): 1109. http://dx.doi.org/10.3390/ph14111109.

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The 2-phenoxybenzamide 1 from the Medicines for Malaria Venture Malaria Box Project has shown promising multi-stage activity against different strains of P. falciparum. It was successfully synthesized via a retrosynthetic approach. Subsequently, twenty-one new derivatives were prepared and tested for their in vitro activity against blood stages of the NF54 strain of P. falciparum. Several insights into structure-activity relationships were revealed. The antiplasmodial activity and cytotoxicity of compounds strongly depended on the substitution pattern of the anilino partial structure as well a

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10

Singh, Kawaljit, Gurminder Kaur, Faith Mjambili, Peter J. Smith, and Kelly Chibale. "Synthesis of metergoline analogues and their evaluation as antiplasmodial agents." Med. Chem. Commun. 5, no. 2 (2014): 165–70. http://dx.doi.org/10.1039/c3md00310h.

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A series of metergoline analogues were synthesized and evaluatedin vitrofor antiplasmodial activity and cytotoxicity towards a mammalian cell line. Some of the compounds exhibited promising selective antiplasmodial activity along with a high selectivity index relative to metergoline.

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