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Journal articles on the topic 'Acute enteric infection'

Author: Grafiati

Published: 28 May 2022

Last updated: 30 July 2025

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1

Tandukar, Sarmila, Jeevan Sherchand, Surendra Karki, et al. "Co-Infection by Waterborne Enteric Viruses in Children with Gastroenteritis in Nepal." Healthcare 7, no. 1 (2019): 9. http://dx.doi.org/10.3390/healthcare7010009.

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Enteric viruses are highly contagious and a major cause of waterborne gastroenteritis in children younger than five years of age in developing world. This study examined the prevalence of enteric virus infection in children with gastroenteritis to identify risk factors for co-infections. In total, 107 stool samples were collected from patients with acute gastroenteritis along with samples of their household drinking water and other possible contamination sources, such as food and hand. The presence of major gastroenteritis-causing enteric virus species (group A rotaviruses, enteroviruses, aden

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2

Khunkheeva, Zh Yu, L. V. Mironova, A. V. Fortunatova, et al. "EPIDEMIOLOGICAL FEATURE OF AN ACUTE ENTERIC INFECTIONS CAUSED BY HALOPHILIC MICROORGANISMS IN THE PRIMORYE TERRITORY." Epidemiology and Infectious Diseases (Russian Journal) 24, no. 3 (2019): 100–107. http://dx.doi.org/10.18821/1560-9529-2019-24-3-100-107.

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A retrospective epidemiological analysis of the incidence of acute enteric infections caused by halophilic microorganisms (V. parahaemolyticus, V. alginolyticus) since 1997 up to 2017 year was carried out in the Primorye Territory. Uneven morbidity levels were established for years of observation with increase in the summer-autumn period, the food-borne transmission was dominant for the acute enteric infection; and mainly people in the 20-30 age group were involved in the epidemic process. Halophilic vibrios are found in surface watercourse of the Vladivostok, Nakhodka, Partizansky and Khasans

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Makimaa, Heyde, Harshad Ingle, and Megan T. Baldridge. "Enteric Viral Co-Infections: Pathogenesis and Perspective." Viruses 12, no. 8 (2020): 904. http://dx.doi.org/10.3390/v12080904.

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Enteric viral co-infections, infections involving more than one virus, have been reported for a diverse group of etiological agents, including rotavirus, norovirus, astrovirus, adenovirus, and enteroviruses. These pathogens are causative agents for acute gastroenteritis and diarrheal disease in immunocompetent and immunocompromised individuals of all ages globally. Despite virus–virus co-infection events in the intestine being increasingly detected, little is known about their impact on disease outcomes or human health. Here, we review what is currently known about the clinical prevalence of v

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Maltseva, Yulia V., and T. A. Kuznetsova. "NOSOCOMIAL INTESTINAL SYNDROME IN CHILDREN: FREQUENCY, STRUCTURE, TREATMENT TACTICS." Russian Pediatric Journal 21, no. 5 (2019): 272–78. http://dx.doi.org/10.18821/1560-9561-2018-21-5-272-278.

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The problem of nosocomial infections (IUI) is relevant in all countries of the world, both industrialized and developing. According to American and European authors, 91-94% of all cases of nosocomial diarrhea are caused by viruses, most often by rotavirus due to high contagiousness. The official statistics on nosocomial acute intestinal infections in the Russian Federation are understated and incomplete. Due to the immediacy of the problem of hospital-acquired enteric infection, there was conducted a retrospective review of 3098 charts of hospital patients (form 003/у) aged from 0 months to 17

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CHEN, S. Y., C. N. TSAI, H. C. CHAO, et al. "Acute gastroenteritis caused by multiple enteric pathogens in children." Epidemiology and Infection 137, no. 7 (2008): 932–35. http://dx.doi.org/10.1017/s095026880800160x.

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SUMMARYOf 303 children hospitalized with acute non-bloody, non-mucoid diarrhoea, 69 (22·8%) had polymicrobial infection, including 52 (17·2%) multiple viral infection and 17 (5·6%) viral and bacterial co-infection. Rotavirus had the most important role in both categories; thus the control of rotavirus infection is crucial for maintaining children's health in Taiwan.

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Shadzhalilova, M. S. "Current clinical features and treatment of acute enteric infections in children." Kazan medical journal 96, no. 1 (2015): 37–42. http://dx.doi.org/10.17750/kmj2015-037.

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Aim. To study the current clinical manifestations and treatment of acute enteric infections in children at an early age.Methods. 225 in the age of 4 months to 3 years were followed-up. Clinical presentations and clinical current of the disease, as well as features and type of gastrointestinal system damage and treatment effects were registered in specially developed report forms. Bacterioloicy, microbiologic, immunologic and genetic tests were used to determine the causative factor of the acute enteric infections. Principal component analysis was used for mathematical modelling and factorial a

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Osmanov, I. M., O. N. Solodovnikova, S. N. Borzakova, T. V. Sbrodova, P. N. Iliasova та S. N. Novoselova. "Поражение пищеварительного тракта как проявление COVID-19 у ребенка 4 лет". Doctor.Ru 20, № 3 (2021): 56–59. http://dx.doi.org/10.31550/1727-2378-2021-20-3-56-59.

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Objective of the Paper: To represent a case of the novel coronavirus infection COVID-19 in a 4-year-old child with isolated bowel damage. Key Points. COVID-19 impacts several systems and organs. Usually, children have mild or asymptomatic disease. Clinical manifestations of COVID-19 in children can be damage not only of respiratory tract, but also of GIT, requiring differential diagnosis of enteric infections (both viral and bacterial). Prompt diagnosis of COVID-19 is essential for antiepidemic measures and suppression an infectious process. The case shows challenges faced by clinicians when d

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Stecher, Bärbel, Günther Paesold, Manja Barthel, et al. "Chronic Salmonella enterica Serovar Typhimurium-Induced Colitis and Cholangitis in Streptomycin-Pretreated Nramp1+/+ Mice." Infection and Immunity 74, no. 9 (2006): 5047–57. http://dx.doi.org/10.1128/iai.00072-06.

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ABSTRACT Salmonella enterica subspecies 1 serovar Typhimurium is an enteric bacterial pathogen infecting a broad range of hosts. In susceptible Nramp1 − / − (Slc11α1 − / −) mice, serovar Typhimurium cannot efficiently colonize the intestine but causes a systemic typhoid-like infection. However, after pretreatment with streptomycin, these susceptible (C57BL/6 and BALB/c) mice develop acute serovar Typhimurium-induced colitis (M. Barthel et al., Infect. Immun. 71:2839-2858, 2003). It was not clear whether resistant Nramp1 +/+ (Slc11α1 +/+) mouse strains would similarly develop colitis. Here we c

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FitzPatrick, R. D., J. R. Noone, R. A. Cartwright, et al. "A33 EOSINOPHILS PROMOTE SALMONELLA TYPHIMURIUM COLONIZATION IN THE MURINE SMALL INTESTINE." Journal of the Canadian Association of Gastroenterology 7, Supplement_1 (2024): 18. http://dx.doi.org/10.1093/jcag/gwad061.033.

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Abstract Background During inflammatory bowel disease (IBD) both the number of intestinal eosinophils and susceptibility to enteric bacterial infections can drastically increase. It is unknown, however, whether eosinophils recruited to the tissues lining the gastrointestinal (GI) tract during severe disease help to control pathogenic bacterial colonization or whether their presence promotes bacterial infection. No studies to date have examined the role of eosinophils during an acute bacterial infection in the small intestine. Aims Our research aims to uncover the role of eosinophils during an

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Kuliyeva, Z. M., and L. I. Rustamova. "THE SYNDROMES APPEARING IN CHILDREN OF EARLY AGE WITH ACUTE ENTERIC INFECTIONS IN URGENT CONDITIONS." National Journal of Neurology 2, no. 19 (2019): 55–60. http://dx.doi.org/10.61788/njn.v2i19.09.

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The clinical syndroms developing in children of early age with acute enteric infections in urgent conditions have been analysed. 338 children of early age with urgent conditions have been observed by bacteriological, serological and molecular-biological methods. It was determined that in observing patients in 63.0% of cases the exicosis, in 21,6% - cramp, in 15,9% - cardiovascular insufficiency, in 15,0% - pulmonary insufficiency, in 12,1% - neurotoxicosis, in 6,8% - infectious - toxic shock have been registrated. In accordingly to our clinic observations the neurotoxicosis appear in children

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Martinez Rodriguez, Nadine R., Marjannie D. Eloi, Alexandria Huynh, et al. "Expansion of Paneth Cell Population in Response to Enteric Salmonella enterica Serovar Typhimurium Infection." Infection and Immunity 80, no. 1 (2011): 266–75. http://dx.doi.org/10.1128/iai.05638-11.

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ABSTRACTPaneth cells residing at the base of the small intestinal crypts contribute to the mucosal intestinal first line defense by secreting granules filled with antimicrobial polypeptides including lysozyme. These cells derive from the columnar intestinal stem cell located at position 0 and the transit amplifying cell located at position +4 in the crypts. We have previously shown thatSalmonella entericaserovar Typhimurium (ST), a leading cause of gastrointestinal infections in humans, effects an overall reduction of lysozyme in the small intestine. To extend this work, we examined small-inte

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Crain, Matthew A., and Justin T. Kupec. "Superimposed Infectious Colitis in Crohn’s Disease." Case Reports in Gastroenterology 15, no. 2 (2021): 475–77. http://dx.doi.org/10.1159/000513976.

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The differential diagnosis for an acute Crohn’s flare should include enteric infection, a challenging yet critical distinction to make when determining appropriate therapy. Since both present similarly, identification of an enteric infection should be performed with comprehensive stool microbial testing. In the setting of moderate-to-severe disease, patients on biologic therapy may be more prone to infectious complications. We present a patient with chronic Crohn’s disease with an unusual, previously undetected enteric infection due to <i>Plesiomonas shigelloides.</i> Once identifi

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13

Sherman, Philip M. "Intussusception is another complication of acute bacterial enteric infection." Journal of Pediatrics 156, no. 5 (2010): A3. http://dx.doi.org/10.1016/j.jpeds.2010.03.017.

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14

Arenas-Pinto, A., G. Certad, G. Ferrara, J. Castro, M. A. Bello, and L. T. Núñez. "Association between parasitic intestinal infections and acute or chronic diarrhoea in HIV-infected patients in Caracas, Venezuela." International Journal of STD & AIDS 14, no. 7 (2003): 487–92. http://dx.doi.org/10.1258/095646203322025812.

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A cross sectional survey was conducted to determine the association between enteric parasites and diarrhoea in HIV-infected adults in Caracas. Three hundred and four patients were evaluated: 104 had acute diarrhoea, 113 chronic diarrhoea and 87 were controls. Isopora belli infection was associated with acute ( P = 0.022) and chronic diarrhoea ( P = 0.003), Entamoeba histolytica/dispar infection was also associated with both acute ( P = 0.015) and chronic diarrhoea ( P = 0.017). Strongyloides stercoralis ( P = 0.003), and Cryptosporidium parvum ( P = 0.017) infections were associated mainly wit

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15

Leung, Wai K., Ka-fai To, Paul K. S. Chan, et al. "Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection." Gastroenterology 125, no. 4 (2003): 1011–17. http://dx.doi.org/10.1016/s0016-5085(03)01215-0.

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Johnson, Charles S., Michael J. Wannemuehler, and Jesse M. Hostetter. "Persistent enteric mycobacterial infection enhances sensitivity to acute mucosal injury." Experimental Biology and Medicine 236, no. 1 (2011): 36–43. http://dx.doi.org/10.1258/ebm.2010.010152.

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17

Thwiny, Hazim Talib, Nawar Jasim Alsalih, Zeayd Fadhil Saeed, Ali Mosa Rashid Al-Yasari, Moyed Abd AlHussein Al-Saadawe, and Mohenned Abd ElHussein Alsaadawi. "Prevalence and seasonal pattern of enteric viruses among hospitalized children with acute gastroenteritis in Samawah, Iraq." Journal of Medicine and Life 15, no. 1 (2022): 52–57. http://dx.doi.org/10.25122/jml-2021-0158.

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Almost all of the deaths happening under the age of 5 occur in the developed countries of Africa and Asia. This study included children admitted to the surgical care, aged 6 months to 5 years, who suffered from acute gastroenteritis and received treatment at Samawah, Iraq, from December 2018 to December 2019. Test results detected different types of rotaviruses, adenoviruses, astroviruses using ELISA. 56.6% of the infections were attributed to a viral pathogen. The main cause was attributed to rotavirus and adenovirus. The causative agents of diarrheal diseases in 28.1% of cases are rotaviruse

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Dallari, Simone, Thomas Heaney, Adriana Rosas, and Ken Cadwell. "Functional characterization of the enteric animal virome." Journal of Immunology 202, no. 1_Supplement (2019): 191.9. http://dx.doi.org/10.4049/jimmunol.202.supp.191.9.

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Abstract The enteric virome includes viruses that infect eukaryotic cells in the gut and is one constituent of the mammalian microbiome. Although best known for causing acute diarrheal disease, many of these viruses are detected in asymptomatic individuals. The immune consequence of harboring these viruses is unclear. We recently demonstrated that norovirus infection promotes the development of the mucosal immune system in mice in a manner similar to symbiotic bacteria, and can protect against models of chemical and microbial injury. These results are reminiscent of findings from the microbiom

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Dykes, E. H., I. W. Clare Garland, and G. R. Gray. "Yersinia Pseudotuberculosis with Inflammation of the Appendix: A Case Report." Scottish Medical Journal 32, no. 3 (1987): 82–83. http://dx.doi.org/10.1177/003693308703200310.

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Human enteric infection with Yersinia enterocolitica or Yersinia pseudotuberculosis may masquerade clinically as acute appendicitis but it is unusual for the appendix to be histologically inflamed. We report a case of Yersinia pseudotuberculosis infection in which acute appendicitis was present in the absence of terminal ileitis.

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Hart, Michael H., Robert Kruger, Stephen Nielsen, and Stuart S. Kaufman. "Acute Self‐Limited Colitis Associated with Cryptosporidium in an Immunocompetent Patient." Journal of Pediatric Gastroenterology and Nutrition 8, no. 3 (1989): 401–3. http://dx.doi.org/10.1002/j.1536-4801.1989.tb09776.x.

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SUMMARYA case report of acute self‐limiting colitis associated with enteric Cryptosporidium infection in an immunocompetent child is presented. This case broadens the spectrum of symptoms and manifestation of Cryptosporidium infection in a normal human host.

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Blohmke, Christoph J., Thomas C. Darton, Claire Jones, et al. "Interferon-driven alterations of the host’s amino acid metabolism in the pathogenesis of typhoid fever." Journal of Experimental Medicine 213, no. 6 (2016): 1061–77. http://dx.doi.org/10.1084/jem.20151025.

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Enteric fever, caused by Salmonella enterica serovar Typhi, is an important public health problem in resource-limited settings and, despite decades of research, human responses to the infection are poorly understood. In 41 healthy adults experimentally infected with wild-type S. Typhi, we detected significant cytokine responses within 12 h of bacterial ingestion. These early responses did not correlate with subsequent clinical disease outcomes and likely indicate initial host–pathogen interactions in the gut mucosa. In participants developing enteric fever after oral infection, marked transcri

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Phogat, Vishal, and Harvir S. Gambhir. "Community Associated Methicillin-Resistant Staphylococcus Aureus Causing Acute Urinary Tract Infection and Epididymo-Orchitis: A Case Report." International Journal of Clinical Case Reports and Reviews 11, no. 3 (2022): 01–02. http://dx.doi.org/10.31579/2690-4861/227.

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Acute epididymitis is most commonly infectious in etiology, usually secondary to a urinary tract infection (UTI) or a sexually transmitted infections (like gonorrhea and chlamydia). Enteric gram-negative bacteria (like Escherichia coli) and coagulase-negative Staphylococcus saprophyticus are the most frequently encountered organisms associated with UTIs. Staphylococcus aureus, especially methicillin-resistant Staphylococcus aureus (MRSA), is an uncommon pathogen when considering community associated acute UTI and acute epididymitis. We present an unusual case of a 28-years-old immunocompetent

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Anischenko, E. V., E. L. Krasavtsev, and A. B. Michnovskaya. "CLINICAL AND DIAGNOSTIC VALUE OF ANTIBODIES TO CONDITIONAL-PATHOGENIC FLORA IN PATIENTS WITH ACUTE ENTERIC INFECTION." Health and Ecology Issues, no. 2 (June 28, 2006): 63–66. http://dx.doi.org/10.51523/2708-6011.2006-3-2-12.

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The titers of antibodies to conditional-pathogenic flora (Klebsiella, Escherichia coli, Pseudomonas aeruginosa) in 83 of patients with acute enteric infections and 201 donors were detected. High titers of antibodies to conditional-pathogenic flora in patients with enteric infections to Klebsiella, Escherichia coli, Pseudomonas aeruginosa were met significantly more often than in donors. Case records of patients with high titers of antibodies to conditional-pathogenic flora were analyzed. High titers of antibodies to conditional-pathogenic flora in younger patients and women with acute enteric

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Kozhukhova, E. A., and I. V. Gorbova. "Characteristics of acute diarrhea adult cases with samples positive for Norwalk virus." Russian Journal of Infection and Immunity 9, no. 2 (2019): 375–80. http://dx.doi.org/10.15789/2220-7619-2019-2-375-380.

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Remaining unmanageable,Norwalkvirus infection is clearly tended to be recorded at higher rate, including adult patients. In many cases, clinical picture of adult acute diarrhea in patients positive for Norwalk virus in clinical samples vs. pathogenetically-caused norovirus infection differs, thereby justifying comparison of clinical and laboratory data. A cohort retrospective study with 146 hospitalized adult patients suffering from acute moderate diarrhea positive for fecalNorwalkvirus was performed. Along with standard laboratory tests (culturing, serologic for detecting 4-fold increase in t

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Hardman, B. K., and L. C. Osborne. "A262 DIFFERENTIAL PHENOTYPES AND LOCALIZATION OF CD8+ T CELL RESPONSES TO ACUTE AND CHRONIC ENTERIC VIRAL INFECTION." Journal of the Canadian Association of Gastroenterology 3, Supplement_1 (2020): 139–40. http://dx.doi.org/10.1093/jcag/gwz047.261.

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Abstract Background Human Norovirus infection is the most common viral cause of gastroenteritis globally and the second most reported viral infection in Canada after the common cold. Most infections are acute, symptomatic, and rapidly cleared but some cases persist asymptomatically or induce post-infectious irritable bowel syndrome. Despite the global burden of these infections, no vaccine to prevent disease exists nor is the mechanism for persistence understood. MNV-CW3 and MNV-CR6 are murine noroviruses which demonstrate distinct biological behaviors that correlate with differential quantity

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Abd-Aljabar, Esraa Mahdi, and Ahmed Abdul jabbar Jaloob Aljanaby. "ROLE OF MACROPHAGE MIGRATION INHIBITORY FACTOR, CLUSTER OF DIFFERENTIATION 19 AND INTERLEUKIN 23 IN INDIVIDUALS INFECTED WITH Salmonella typhi." Journal of Experimental Biology and Agricultural Sciences 9, no. 3 (2021): 394–400. http://dx.doi.org/10.18006/2021.9(3).394.400.

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Salmonella enterica serovar typhi (S.typhi) is one of the most important gram negative bacteria that cause enteric fever and stimulate the immune response in infected patients. This study aimed to compare the humoral and cellular immune responses in patients infected with S.typhi. For this, the concentration of three immunological markers viz., Macrophage migration inhibitory factor (MIF), Cluster of Differentiation 19 (CD19), and Interleukin 23 (IL-23) were measured by the Enzyme-Linked Immunosorbent Assay in the serum of 54 S.typhi infected patients, and 31 healthy individuals. The results d

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Orandle, Marlene S., Ronald S. Veazey, and Andrew A. Lackner. "Enteric Ganglionitis in Rhesus Macaques Infected with Simian Immunodeficiency Virus." Journal of Virology 81, no. 12 (2007): 6265–75. http://dx.doi.org/10.1128/jvi.02671-06.

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ABSTRACT Gastrointestinal (GI) disease is a debilitating feature of human immunodeficiency virus (HIV) infection that can occur in the absence of histopathological abnormalities or identifiable enteropathogens. However, the mechanisms of GI dysfunction are poorly understood. The present study was undertaken to characterize changes in resident and inflammatory cells in the enteric nervous system (ENS) of macaques during the acute stage of simian immunodeficiency virus (SIV) infection to gain insight into potential pathogenic mechanisms of GI disease. Ganglia from duodenum, ileum, and colon were

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Marascio, Nadia, Grazia Pavia, Brunella Brescia, et al. "Prevalence of Enteric Pathogens and Antibiotic Resistance: Results of a Six-Year Active Surveillance Study on Patients Admitted to a Teaching Hospital." Antibiotics 13, no. 8 (2024): 726. http://dx.doi.org/10.3390/antibiotics13080726.

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Background: Acute Infectious Diarrhea (AID) and the short- and long-term complications associated with it are major causes of hospitalization worldwide. In Italy, due to a lack of robust surveillance programs, only limited data has been collected on their prevalence and circulation. This study aims to evaluate the resistance pattern of enteric pathogens and their epidemiological trends over a six-year period. Methods: This cross-sectional retrospective study was conducted from January 2018 to December 2023. Stool samples were analyzed during routine diagnosis with culture methods, syndromic mo

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Barman, Rantu, and S. Sudharshanam. "Sepsis with Triple Tropical Co-infection in Assam: A Rare Case Report." Assam Journal of Internal Medicine 15, no. 1 (2025): 50–53. https://doi.org/10.4103/ajoim.ajoim_16_25.

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Abstract Tropical infections are the leading causes for acute undifferentiated febrile illness in India. Malaria, dengue, chikungunya, scrub typhus, leptospirosis, enteric fever, and seasonal influenza are the commonest causes of acute febrile illness in tropical and sub-tropical regions including North Eastern states of India. Co-infection is not uncommon in tropical regions, which can cause significant impacts on disease severity and its outcome and can pose challenges for diagnosis and management. This report aims to increase the attention of the physicians in considering the possibility of

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Yan, Quanhui, Xiaodi Liu, Yawei Sun, et al. "Swine Enteric Coronavirus: Diverse Pathogen–Host Interactions." International Journal of Molecular Sciences 23, no. 7 (2022): 3953. http://dx.doi.org/10.3390/ijms23073953.

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Swine enteric coronavirus (SeCoV) causes acute gastroenteritis and high mortality in newborn piglets. Since the last century, porcine transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhea virus (PEDV) have swept farms all over the world and caused substantial economic losses. In recent years, porcine delta coronavirus (PDCoV) and swine acute diarrhea syndrome coronavirus (SADS-CoV) have been emerging SeCoVs. Some of them even spread across species, which made the epidemic situation of SeCoV more complex and changeable. Recent studies have begun to reveal the complex SeCoV–ho

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Haake, Christine, Sarah Cook, Nicola Pusterla, and Brian Murphy. "Coronavirus Infections in Companion Animals: Virology, Epidemiology, Clinical and Pathologic Features." Viruses 12, no. 9 (2020): 1023. http://dx.doi.org/10.3390/v12091023.

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Coronaviruses are enveloped RNA viruses capable of causing respiratory, enteric, or systemic diseases in a variety of mammalian hosts that vary in clinical severity from subclinical to fatal. The host range and tissue tropism are largely determined by the coronaviral spike protein, which initiates cellular infection by promoting fusion of the viral and host cell membranes. Companion animal coronaviruses responsible for causing enteric infection include feline enteric coronavirus, ferret enteric coronavirus, canine enteric coronavirus, equine coronavirus, and alpaca enteric coronavirus, while c

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Mansour, Adel M., Montasser El Koutby, Mohamed M. El Barbary, et al. "Enteric viral infections as potential risk factors for intussusception." Journal of Infection in Developing Countries 7, no. 01 (2013): 028–35. http://dx.doi.org/10.3855/jidc.2321.

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Introduction: We aimed to identify potential risk factors for intussusception (ISS) among children presenting to two pediatric hospitals in Egypt. Methodology: In this case-control study, enrolled children < 3 years old with ISS (confirmed radiologically and/or surgically) were matched by age and gender to controls admitted with acute non-abdominal surgical illnesses. Stool samples were collected and tested for various enteric bacteria, rotavirus, enteric adenoviruses (EA, 40 and 41) and astroviruses using commercially available ELISA diagnostic kits. Results: From December 2004 to May 2009

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Zhang, Li, Jaewon Song, Newsha Gheshm, Anthony Orvedahl, and Sanghyun Lee. "Loss of Trex1 in intestinal epithelial cells prevents enteric viral infections." Journal of Immunology 212, no. 1_Supplement (2024): 0754_6281. http://dx.doi.org/10.4049/jimmunol.212.supp.0754.6281.

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Abstract The host intestinal microbiota comprises bacteria, viruses, fungi, multicellular parasites, and archaea, which directly impact host’s health. Norovirus and rotavirus are agents of acute infectious gastroenteritis with symptoms of vomiting and watery diarrhea. These viruses are restrained by interferons, especially IFN-α and IFN-λ. The Tree-prime Repair Exonuclease 1 (Trex1) is a nonprocessive 3’→5’ exonuclease that degrades cytosolic nucleic acids. Mutations in Trex1 are associated with a broad spectrum of inflammatory and autoimmune diseases. Failure to degrade cytosolic DNA activate

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Boelke, Mathias, Christina Puff, Kathrin Becker, et al. "Enteric Ganglioneuritis, a Common Feature in a Subcutaneous TBEV Murine Infection Model." Microorganisms 9, no. 4 (2021): 875. http://dx.doi.org/10.3390/microorganisms9040875.

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Tick-borne encephalitis (TBE) is a severe neurologic disease in Europe and Asia. Disease expression ranges from asymptomatic to severe neurological clinical pictures, involving meningitis, encephalitis, meningoencephalitis and potentially fatal outcome. Humans mostly become infected with TBE virus (TBEV) by the bite of an infected tick. Gastrointestinal (GI) symptoms in humans are mainly attributed to the first viremic phase of TBEV infection with unspecific symptoms and/or resulting from severe neurological impairment of the central nervous system (CNS). We used the subcutaneous TBEV-infectio

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Sahoo, Bishnupriya, Karunesh Kumar, Smita Malhotra, and Anupam Sibal. "Enteric fever masquerading as Crohn’s disease in a child with abdominal tuberculosis." BMJ Case Reports 16, no. 2 (2023): e249531. http://dx.doi.org/10.1136/bcr-2022-249531.

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In tropical countries, like India, various types of infectious diseases like tuberculosis, enteric fever, malaria and dengue are prevalent. Disease trend over time has been gradually shifting from infective to inflammatory frame because of increasing awareness regarding hygiene and increasing immunisation coverage. This case report describes an adolescent boy having a long history of abdominal pain, bleeding per rectum and documented weight loss, presented with an acute episode of fever. But the coexisting infections and/or inflammatory conditions presented challenges to the treating physician

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Reggiardo, Carlos, Thomas J. Fuhrmann, Gavin L. Meerdink, and Edward J. Bicknell. "Diagnostic Features of Chlamydia Infection in Dairy Calves." Journal of Veterinary Diagnostic Investigation 1, no. 4 (1989): 305–8. http://dx.doi.org/10.1177/104063878900100405.

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Chlamydia were routinely isolated from a group of calves with pneumonia, systemic disease, and enteric involvement. The most commonly observed lesions were acute interstitial pneumonia, hepatitis, and enteritis. Cultures of sequentially collected nasal and rectal samples from clinically normal calves revealed a large percentage of inapparent infections during, at least, the first 30 days of age.

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Parizhskaya, Maria, Janet Walpusk, George Mazariegos, and Ronald Jaffe. "Enteric Adenovirus Infection in Pediatric Small Bowel Transplant Recipients." Pediatric and Developmental Pathology 4, no. 2 (2001): 122–28. http://dx.doi.org/10.1007/s100240010132.

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Three of 70 small bowel transplant recipients were diagnosed with adenovirus enteritis. The biopsies were performed for surveillance in one patient at 2.7 years after transplantation and in two symptomatic children 1.5 years and 4.5 months after transplantation. In all three patients the characteristic epithelial changes were not noted by the primary observers. Two biopsies had been called “suggestive of acute rejection” and both patients had been so treated. One biopsy had been diagnosed as “regenerative”. Once the epithelial changes were recognized as being viral, confirmation was possible b

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Lerner, Aaron, and Mark F. McCarty. "The Aging Bowel Dysfunction and Elderly Vulnerability towards COVID-19 Infection." Life 11, no. 2 (2021): 97. http://dx.doi.org/10.3390/life11020097.

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Severe acute respiratory syndrome coronavirus 2, primarily a respiratory tract virus, also affects the enteric organs. The most affected sector of the community are the retirement and nursing home elderly residents. Along their life the senescent gastrointestinal functions are deteriorating and failing to fully execute their digestive, absorptive, mucosal barriers, and immune protective duties. Adding the decreased motility, increased intestinal permeability, dysbiosis, morbid chronic disease background, the consumed polypharmacy enteric adverse effects to the presence of the SARS-CoV-2 host r

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Akhtar, Samina, Belqees Yawar Faiz, Khurram Khaliq Bhinder, Salma Gul, Ijaz A.Khan, and Madiha Saeed Wahla. "UNUSUAL PRESENTATION OF REACTIVE ARTHRITIS AFTER SALMONELLA ENTERITIS IN A 6-YEAR-OLD BOY." Pakistan Postgraduate Medical Journal 32, no. 01 (2021): 48–51. http://dx.doi.org/10.51642/ppmj.v32i01.407.

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ABSTRACT: Reactive arthritis, formerly called Reiter’s syndrome is extra-articular oligoarthropathy, which can be due to bacterial infection or genetic predisposition. The infections are either urogenital (chlamydia being most notorious) or gastrointestinal (e.g. salmonella, yersinia, etc.). The human leukocyte antigen (HLA-B27) antigen has been implicated as the most common predisposing factor. Reactive arthritis often involves the joints of the lower limb. Bacterial enteric infections are a potential threat in a Pediatric population that can be due to an acute illness or its sequelae.

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Cieza, Roberto J., Jonathan L. Golob, Justin A. Colacino, and Christiane E. Wobus. "Comparative Analysis of Public RNA-Sequencing Data from Human Intestinal Enteroid (HIEs) Infected with Enteric RNA Viruses Identifies Universal and Virus-Specific Epithelial Responses." Viruses 13, no. 6 (2021): 1059. http://dx.doi.org/10.3390/v13061059.

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Acute gastroenteritis (AGE) has a significant disease burden on society. Noroviruses, rotaviruses, and astroviruses are important viral causes of AGE but are relatively understudied enteric pathogens. Recent developments in novel biomimetic human models of enteric disease are opening new possibilities for studying human-specific host–microbe interactions. Human intestinal enteroids (HIE), which are epithelium-only intestinal organoids derived from stem cells isolated from human intestinal biopsy tissues, have been successfully used to culture representative norovirus, rotavirus, and astrovirus

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Sosnowski, O., T. Allain, E. Fekete, D. M. Mckay, and A. Buret. "A56 TUFT CELL RESPONSES DURING ACUTE- AND LATE-STAGE GIARDIA INFECTION." Journal of the Canadian Association of Gastroenterology 5, Supplement_1 (2022): 64–65. http://dx.doi.org/10.1093/jcag/gwab049.055.

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Abstract Background Epithelial tuft cells can detect and respond to enteric infections and appear to help clear some intestinal parasites. Through tuft cell luminal surface receptors, tuft cells can sense ligands directly supplied by a parasite, or indirectly via excretory/secretory products. We hypothesize that microbiome alterations may also modulate tuft cell-derived gut responses. Tuft cells release the alarmin cytokine IL-25 which, upon acting on type 2 innate lymphoid cells (ILC2), ultimately lead to tuft and goblet cell hyperplasia. Upon helminth infections, tuft and goblet cell hyperpl

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Rikhotso, Mpumelelo Casper, Ronewa Khumela, Jean Pierre Kabue, Afsatou Ndama Traoré-Hoffman, and Natasha Potgieter. "Predominance of Human Bocavirus Genotype 1 and 3 in Outpatient Children with Diarrhea from Rural Communities in South Africa, 2017–2018." Pathogens 9, no. 4 (2020): 245. http://dx.doi.org/10.3390/pathogens9040245.

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Human bocavirus (HBoV) is an emerging virus globally associated with diarrhea in young children. This study aims to investigate the prevalence of HBoV genotypes in children (≤5 years) from rural communities in South Africa (SA) suffering from acute gastroenteritis (AGE). A total of 141 fecal samples of children ≤5 years with acute gastroenteritis (AGE) were collected from rural primary health care facilities in the Vhembe district of SA between June 2017 and July 2018. Clinical symptoms and demographic data were also recorded. A total of 102 (72%) were outpatients, and 39 (28%) were hospitaliz

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Aggarwal, Somya, Ebrahim Hassan, and Megan T. Baldridge. "Experimental Methods to Study the Pathogenesis of Human Enteric RNA Viruses." Viruses 13, no. 6 (2021): 975. http://dx.doi.org/10.3390/v13060975.

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Every year, millions of children are infected with viruses that target the gastrointestinal tract, causing acute gastroenteritis and diarrheal illness. Indeed, approximately 700 million episodes of diarrhea occur in children under five annually, with RNA viruses norovirus, rotavirus, and astrovirus serving as major causative pathogens. Numerous methodological advancements in recent years, including the establishment of novel cultivation systems using enteroids as well as the development of murine and other animal models of infection, have helped provide insight into many features of viral path

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Yazici, Vesile, Yildiz Manzur, and Aynur Akbulut. "Investigation of Rotavirus and Enteric Adenovirus Infection Frequency in Cases with Acute Gastroenteritis." Klimik Dergisi/Klimik Journal 26, no. 1 (2014): 13–16. http://dx.doi.org/10.5152/kd.2013.04.

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Gül, Ersin, Ursina Enz, Luca Maurer, et al. "Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells during Salmonella gut infection." PLOS Pathogens 19, no. 6 (2023): e1011235. http://dx.doi.org/10.1371/journal.ppat.1011235.

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Recruitment of neutrophils into and across the gut mucosa is a cardinal feature of intestinal inflammation in response to enteric infections. Previous work using the model pathogen Salmonella enterica serovar Typhimurium (S.Tm) established that invasion of intestinal epithelial cells by S.Tm leads to recruitment of neutrophils into the gut lumen, where they can reduce pathogen loads transiently. Notably, a fraction of the pathogen population can survive this defense, re-grow to high density, and continue triggering enteropathy. However, the functions of intraluminal neutrophils in the defense

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Dale, Anne, Julian E. Thomas, Momadoe K. Darboe, W. Andrew Coward, Marilyn Harding, and Lawrence T. Weaver. "Helicobacter pylori Infection, Gastric Acid Secretion, and Infant Growth." Journal of Pediatric Gastroenterology and Nutrition 26, no. 4 (1998): 393–97. http://dx.doi.org/10.1002/j.1536-4801.1998.tb00805.x.

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ABSTRACTBackground:Helicobacter pylori infection is very common in Gambian infants and children, who are also at risk of chronic diarrhoea and undernutrition. Acute H. pylori infection is associated with depressed gastric acid secretion, and loss of the gastric acid barrier may predispose to enteric infections.Methods:In a prospective study a noninvasive test of gastric acid output(measurement of change in urine acid output before and after a feed) was performed on a population of Gambian infants at high risk of H. pylori infection. The 13C urea breath tests was used to measure the prevalence

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Malysh, N. G., and A. P. Podavalenko. "EVALUATION AND PREDICTIVE METHODS OF EPIDEMICAL SITUATION IN THE AREA OF ACUTE ENTERIC INFECTIONS." Annals of Mechnikov Institute, no. 2 (June 7, 2017): 39–44. https://doi.org/10.5281/zenodo.803864.

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<strong>Introduction.</strong> Despite the fact, that nowadays acute intestinal infections (AII) sick rate is decreasing, the aggravation of the epidemical situation is always there. Increased attention to AII caused by unpredictable epidemical rises of the AII diseases, which cannot be prevented without assessing the epidemical situation of these infections and forecasting of the levels of sick rate. However, developed mathematical methods of forecasting in most cases do not take into account the risk factors, also they are time-consuming and it is difficult to calculate them; and developed s

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Albayrak, Ayse, Sibel Seda Gunbey, and Ferda Aktas. "Cholestatic hepatitis due to Salmonella typhi." Clinics and Practice 1, no. 1 (2011): 13. http://dx.doi.org/10.4081/cp.2011.e13.

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Salmonella infection occurs worldwide and is still an important public health problem in many developing countries. The infection can affect almost all major organs including the liver. Severe hepatic involvement with a clinical feature of acute hepatitis is a rare complication. In this paper, a 39-year-old male with acute cholestatic typhoid hepatitis is presented. The case had a tender hepatomegaly and elevated serum alanine and aspartate transaminase, alkaline phosphatase, and gamma glutamyl transferase levels; these features cannot been distinguished from those of acute viral hepatitis. Se

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Yang, Qi-Yue, Yong-Le Yang, Yi-Xin Tang, et al. "Bile acids promote the caveolae-associated entry of swine acute diarrhea syndrome coronavirus in porcine intestinal enteroids." PLOS Pathogens 18, no. 6 (2022): e1010620. http://dx.doi.org/10.1371/journal.ppat.1010620.

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Intestinal microbial metabolites have been increasingly recognized as important regulators of enteric viral infection. However, very little information is available about which specific microbiota-derived metabolites are crucial for swine enteric coronavirus (SECoV) infection in vivo. Using swine acute diarrhea syndrome (SADS)-CoV as a model, we were able to identify a greatly altered bile acid (BA) profile in the small intestine of infected piglets by untargeted metabolomic analysis. Using a newly established ex vivo model–the stem cell-derived porcine intestinal enteroid (PIE) culture–we dem

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Britkova, T. A., K. E. Panteleev, and O. A. Pazinenko. "Clinical and etiological characteristics of mixed infections in children in the Izhevsk hospital." CHILDREN INFECTIONS 21, no. 4 (2022): 53–56. http://dx.doi.org/10.22627/2072-8107-2022-21-4-53-56.

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Aim: to study the structure, features of the findings and treatment of mixed infections in children at the present stage.Materials and methods. 85 case histories of children aged 5 months to 17 years and 10 months were examined, the final diagnosis of which included 2 or more infections on the basis of the children's infectious diseases department City Clinical Hospital № 7 of Izhevsk. Children with acute infectious pathology (acute intestinal infections, acute respiratory infections, herpes infections) are hospitalized in this hospital. Diagnostic methods: polymerase chain reaction, ELISA, ba

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