Log in

Relevant bibliographies by topics / Acute otitis media Haemophilus influenzae / Journal articles

To see the other types of publications on this topic, follow the link: Acute otitis media Haemophilus influenzae.

Journal articles on the topic 'Acute otitis media Haemophilus influenzae'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Acute otitis media Haemophilus influenzae.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Antonelli, Patrick J., Kathleen A. Daly, Steven K. Juhn, Erik J. Veum, George L. Adams, and G. Scott Giebink. "Tobacco Smoke and Otitis Media in the Chinchilla Model." Otolaryngology–Head and Neck Surgery 111, no. 4 (1994): 513–18. http://dx.doi.org/10.1177/019459989411100421.

Full text

Abstract:

To determine whether tobacco smoke contributes to the pathogenesis of acute otitis media, chinchillas were exposed to mainstream tobacco smoke or sham conditions (cigarettes not lit) In a Walton smoke exposure machine for 20-minute cycles two or three times daily. After 6 to 8 weeks of daily exposure. 12 chinchillas were nasally injected with Streptococcus pneumoniae, and 18 chinchillas were injected into both middle ears with nontypable Haemophilus Influenzae. Smoke or sham exposures were continued for 2 to 4 weeks after injection. Otitis media developed in none of the 12 nasally injected chi

APA, Harvard, Vancouver, ISO, and other styles

2

WALD, ELLEN R. "Haemophilus influenzae as a cause of acute otitis media." Pediatric Infectious Disease Journal 8, Supplement (1989): S31. http://dx.doi.org/10.1097/00006454-198901001-00012.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Alzbutienė, Giedrė, Ann Hermansson, Per Cayè-Thomasen, and Vytenis Kinduris. "Tympanic membrane changes in experimental acute otitis media and myringotomy." Medicina 44, no. 4 (2008): 313. http://dx.doi.org/10.3390/medicina44040041.

Full text

Abstract:

Objective. The present experimental study explored pathomorphological changes and calcium depositions in the tympanic membrane during experimental acute otitis media caused by nontypeable Haemophilus influenzae in myringotomized and nonmyringotomized ears. Material and methods. A rat model of experimental acute otitis media caused by nontypeable Haemophilus influenzae was employed. Sixteen Sprague-Dawley rats were used. Four days following middle ear inoculation, a bilateral myringotomy was performed in six randomly selected animals. Another group of 10 animals was inoculated only. On days 4,

APA, Harvard, Vancouver, ISO, and other styles

4

Babin, Emmanuel, Vincent Lemarchand, Sylvain Moreau, Marc Goullet de Rugy, André Valdazo, and Arnaud Bequignon. "Failure of antibiotic therapy in acute otitis media." Journal of Laryngology & Otology 117, no. 3 (2003): 173–76. http://dx.doi.org/10.1258/002221503321192449.

Full text

Abstract:

The aim of this retrospective study was to determine the possible causes of failure of antibiotic therapy in children with acute otitis media (AOM). Thirty-nine samples of middle-ear fluid were obtained by myringotomy from 31 children suffering from AOM, unrelieved by antibiotic therapy administered for over 48 hours. The samples were analysed by the usual microbiological techniques, including cultures, tests for beta-lactamase producing strains and the determination of the minimal inhibitory concentration of penicillin for Streptococcus pneumoniae. In 14 samples, no bacterial strains were det

APA, Harvard, Vancouver, ISO, and other styles

5

Sugita, Rinya, Yutaka Fujimaki, and Koichi Deguchi. "Bacteriological features and chemotherapy of adult acute purulent otitis media." Journal of Laryngology & Otology 99, no. 7 (1985): 629–35. http://dx.doi.org/10.1017/s0022215100097395.

Full text

Abstract:

Abstract Eighty-eight patients from 16 to 79 years old, with acute purulent otitis media, were bacteriologically examined at the Otorhinolaryngology Department of a primary care hospital in Tokyo from July 1979 to May 1983. Fifty-six patients underwent paracentesis, and 32 patients exhibited otorrhea due to previous spontaneous perforation of the tympanic membrane.Bacteriologic cultures revealed the presence of Streptococcus pneumoniae (62.5 per cent), including S. pneumoniae Type III (28.1 per cent), Haemophilus influenzae (10.5 per cent), Staphylococcus aureus (11.5 per cent), and Streptococ

APA, Harvard, Vancouver, ISO, and other styles

6

BARENKAMP, STEPHEN J., and FRANK F. BODOR. "Development of serum bactericidal activity following nontypable Haemophilus influenzae acute otitis media." Pediatric Infectious Disease Journal 9, no. 5 (1990): 333–38. http://dx.doi.org/10.1097/00006454-199005000-00006.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Sillanpää, Saara, Sami Oikarinen, Markku Sipilä, et al. "Moraxella catarrhalis Might Be More Common than Expected in Acute Otitis Media in Young Finnish Children." Journal of Clinical Microbiology 54, no. 9 (2016): 2373–79. http://dx.doi.org/10.1128/jcm.01146-16.

Full text

Abstract:

According to studies based on bacterial cultures of middle ear fluids,Streptococcus pneumoniae,Haemophilus influenzae, andMoraxella catarrhalishave been the most common pathogens in acute otitis media. However, bacterial culture can be affected by reduced viability or suboptimal growth of bacteria. PCR detects bacterial DNA from samples with greater sensitivity than culture. In the present study, we analyzed the middle ear pathogens with both conventional culture and semiquantitative real-time PCR in 90 middle ear fluid samples obtained from children aged 5 to 42 months during acute otitis med

APA, Harvard, Vancouver, ISO, and other styles

8

Juliao, Patricia C., Carl F. Marrs, Jingping Xie, and Janet R. Gilsdorf. "Histidine Auxotrophy in Commensal and Disease-Causing Nontypeable Haemophilus influenzae." Journal of Bacteriology 189, no. 14 (2007): 4994–5001. http://dx.doi.org/10.1128/jb.00146-07.

Full text

Abstract:

ABSTRACT Histidine biosynthesis is one of the best studied metabolic pathways in bacteria. Although this pathway is thought to be highly conserved within and between bacterial species, a previous study identified a genetic region within the histidine operon (his) of nontypeable strains of Haemophilus influenzae (NTHI) that was more prevalent among otitis media strains than among throat commensal NTHI strains. In the present study, we further characterized this region and showed that genes in the complete his operon (hisG, -D, -C, -NB, -H, -A, -F, and -IE) are >99% conserved among four fully

APA, Harvard, Vancouver, ISO, and other styles

9

Jacobs, Michael R., Ron Dagan, Peter C. Appelbaum, and Daniel J. Burch. "Prevalence of Antimicrobial-Resistant Pathogens in Middle Ear Fluid: Multinational Study of 917 Children with Acute Otitis Media." Antimicrobial Agents and Chemotherapy 42, no. 3 (1998): 589–95. http://dx.doi.org/10.1128/aac.42.3.589.

Full text

Abstract:

ABSTRACT The management of acute otitis media is complicated by the emergence of resistance to β-lactam and other antibiotics among common pathogens. We conducted a large, international study of infants and children with acute otitis media to identify pathogens and susceptibility patterns. During the winter of 1994 to 1995, middle ear fluid samples were collected from 917 patients with acute otitis media in Bulgaria, the Czech Republic, Hungary, Romania, Slovakia, Israel, and the United States. A single reference laboratory performed in vitro susceptibility testing. Pathogens were isolated fro

APA, Harvard, Vancouver, ISO, and other styles

10

Munson, Robert S., Alistair Harrison, Allison Gillaspy, et al. "Partial Analysis of the Genomes of Two Nontypeable Haemophilus influenzae Otitis Media Isolates." Infection and Immunity 72, no. 5 (2004): 3002–10. http://dx.doi.org/10.1128/iai.72.5.3002-3010.2004.

Full text

Abstract:

ABSTRACT In 1995, The Institute for Genomic Research completed the genomic sequence of a rough derivative of Haemophilus influenzae serotype d, strain KW20. This sequence, though extremely useful in understanding the basic biology of H. influenzae, has yet to provide significant insight into our understanding of disease caused by nontypeable H. influenzae (NTHI), because serotype d strains are not generally pathogens. In contrast, NTHI strains are frequently mucosal pathogens and are the primary pathogens of chronic otitis media as well as a significant cause of acute otitis media in children.

APA, Harvard, Vancouver, ISO, and other styles

11

Foxwell, A. Ruth, Jennelle M. Kyd, and Allan W. Cripps. "Nontypeable Haemophilus influenzae: Pathogenesis and Prevention." Microbiology and Molecular Biology Reviews 62, no. 2 (1998): 294–308. http://dx.doi.org/10.1128/mmbr.62.2.294-308.1998.

Full text

Abstract:

SUMMARY In this paper, we describe the ability of nontypeable Haemophilus influenzae (NTHi) to coexist with the human host and the devastating results associated with disruption of the delicate state of balanced pathogenesis, resulting in both acute and chronic respiratory tract infections. It has been seen that the strains of NTHi causing disease show a marked genetic and phenotypic diversity but that changes in the lipooligosaccharide (LOS) and protein size and antigenicity in chronically infected individuals indicate that individual strains of NTHi can remain and adapt themselves to avoid e

APA, Harvard, Vancouver, ISO, and other styles

12

Dunne, Michael W., Chandra Khurana, Adriano Arguedas Mohs, et al. "Efficacy of Single-Dose Azithromycin in Treatment of Acute Otitis Media in Children after a Baseline Tympanocentesis." Antimicrobial Agents and Chemotherapy 47, no. 8 (2003): 2663–65. http://dx.doi.org/10.1128/aac.47.8.2663-2665.2003.

Full text

Abstract:

ABSTRACT Children with acute otitis media underwent tympanocentesis and were given a single dose of 30 mg of azithromycin/kg of body weight. At day 28, the overall clinical cure rate was 206 of 242 (85%). Clinical cure rates for patients infected with Streptococcus pneumoniae (67 of 76; 88%) and Haemophilus influenzae (28 of 44; 64%) were consistent with historical rates for the 5-day dosing regimen.

APA, Harvard, Vancouver, ISO, and other styles

13

Harrison, Alistair, David W. Dyer, Allison Gillaspy, et al. "Genomic Sequence of an Otitis Media Isolate of Nontypeable Haemophilus influenzae: Comparative Study with H. influenzae Serotype d, Strain KW20." Journal of Bacteriology 187, no. 13 (2005): 4627–36. http://dx.doi.org/10.1128/jb.187.13.4627-4636.2005.

Full text

Abstract:

ABSTRACT In 1995, the Institute for Genomic Research completed the genome sequence of a rough derivative of Haemophilus influenzae serotype d, strain KW20. Although extremely useful in understanding the basic biology of H. influenzae, these data have not provided significant insight into disease caused by nontypeable H. influenzae, as serotype d strains are not pathogens. In contrast, strains of nontypeable H. influenzae are the primary pathogens of chronic and recurrent otitis media in children. In addition, these organisms have an important role in acute otitis media in children as well as o

APA, Harvard, Vancouver, ISO, and other styles

14

Barkai, Galia, Eugene Leibovitz, Noga Givon-Lavi, and Ron Dagan. "Potential Contribution by Nontypable Haemophilus influenzae in Protracted and Recurrent Acute Otitis Media." Pediatric Infectious Disease Journal 28, no. 6 (2009): 466–71. http://dx.doi.org/10.1097/inf.0b013e3181950c74.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Tristram, Stephen, Michael R. Jacobs, and Peter C. Appelbaum. "Antimicrobial Resistance in Haemophilus influenzae." Clinical Microbiology Reviews 20, no. 2 (2007): 368–89. http://dx.doi.org/10.1128/cmr.00040-06.

Full text

Abstract:

SUMMARY Haemophilus influenzae is a major community-acquired pathogen causing significant morbidity and mortality worldwide. Meningitis and bacteremia due to type b strains occur in areas where the protein-conjugated type b vaccine is not in use, whereas nontypeable strains are major causes of otitis media, sinusitis, acute exacerbations of chronic bronchitis, and pneumonia. Antibiotic resistance in this organism is more diverse and widespread than is commonly appreciated. Intrinsic efflux resistance mechanisms limit the activity of the macrolides, azalides, and ketolides. β-Lactamase producti

APA, Harvard, Vancouver, ISO, and other styles

16

Melhus, Åsa, and Allen F. Ryan. "Expression of Cytokine Genes during Pneumococcal and Nontypeable Haemophilus influenzae Acute Otitis Media in the Rat." Infection and Immunity 68, no. 7 (2000): 4024–31. http://dx.doi.org/10.1128/iai.68.7.4024-4031.2000.

Full text

Abstract:

ABSTRACT Acute otitis media (AOM) elicits potent inflammatory responses from the cells of the middle ear mucosa as well as from infiltrating leukocytes. To explore host responses during experimental AOM induced by Streptococcus pneumoniae type 3 and nontypeableHaemophilus influenzae (NTHi), otomicroscopy findings and expression of cytokine genes in the middle ear were monitored up to 1 month postinoculation. The mucosa and infiltrating cells responded rapidly to the bacterial challenge. Otomicroscopically, AOM appeared 1 day after NTHi inoculation and 3 days after pneumococcus inoculation. Pne

APA, Harvard, Vancouver, ISO, and other styles

17

Krasan, Graham P., David Cutter, Stan L. Block, and Joseph W. St. Geme. "Adhesin Expression in Matched Nasopharyngeal and Middle Ear Isolates of Nontypeable Haemophilus influenzaefrom Children with Acute Otitis Media." Infection and Immunity 67, no. 1 (1999): 449–54. http://dx.doi.org/10.1128/iai.67.1.449-454.1999.

Full text

Abstract:

ABSTRACT The HMW1 and HMW2 proteins, Hia, and hemagglutinating pili are important adherence factors in nontypeable Haemophilus influenzae. To gain insight into the relative importance of these adhesins in nasopharyngeal colonization and localized respiratory tract disease, we assessed their expression in matched nasopharyngeal and middle ear isolates of nontypeable H. influenzae from 17 children with acute otitis media. In all patients, including 11 with bilateral disease, the matched isolates were isogenic based on total protein profiles and genomic fingerprints. Of the nasopharyngeal isolate

APA, Harvard, Vancouver, ISO, and other styles

18

Palacios, Sean D., Kwang Pak, Alexander Z. Rivkin, et al. "Role of p38 Mitogen-Activated Protein Kinase in Middle Ear Mucosa Hyperplasia during Bacterial Otitis Media." Infection and Immunity 72, no. 8 (2004): 4662–67. http://dx.doi.org/10.1128/iai.72.8.4662-4667.2004.

Full text

Abstract:

ABSTRACT Hyperplasia of the middle ear mucosa contributes to the sequelae of acute otitis media. Understanding the signal transduction pathways that mediate hyperplasia could lead to the development of new therapeutic interventions for this disease and its sequelae. Endotoxin derived from bacteria involved in middle ear infection can contribute to the hyperplastic response. The p38 mitogen-activated protein kinase (MAPK) is known to be activated by endotoxin as well as cytokines and other inflammatory mediators that have been documented in otitis media. We assessed the activation of p38 in the

APA, Harvard, Vancouver, ISO, and other styles

19

Yadav, Lal Kishor, Prakash Bahadur Thapa, and Jayendra Pradhananga. "Otogenic Intracranial Complications in Bir Hospital; an Eight Years Retrospective Review." Nepalese Journal of ENT Head and Neck Surgery 6, no. 1 (2018): 25–28. http://dx.doi.org/10.3126/njenthns.v6i1.19441.

Full text

Abstract:

Objectives: To review our experiences on intracranial complications secondary to otitis media and to compare the results with other studies.Material and Methods: A retrospective chart review of all patients with intracranial complications secondary to otitis media over eight years period in Bir hospital was done. Clinical presentation, radiological findings, microbiology, surgical management and antibiotics used were studied.Results: Forty eight cases were included in this study of which 23 had meningitis, 15 had brain abscess, 7 had lateral sinus thrombosis and 3 had petrositis. 37 of these w

APA, Harvard, Vancouver, ISO, and other styles

20

Mason, Kevin M., Robert S. Munson, and Lauren O. Bakaletz. "Nontypeable Haemophilus influenzae Gene Expression Induced In Vivo in a Chinchilla Model of Otitis Media." Infection and Immunity 71, no. 6 (2003): 3454–62. http://dx.doi.org/10.1128/iai.71.6.3454-3462.2003.

Full text

Abstract:

ABSTRACT The gram-negative bacterium nontypeable Haemophilus influenzae (NTHI) is the predominant pathogen in chronic otitis media with effusion and, with Streptococcus pneumoniae and Moraxella catarrhalis, is a causative agent of acute otitis media. To identify potential virulence determinants, bacterial gene expression was monitored by differential fluorescence induction during early disease progression in one specific anatomical niche of a chinchilla model of NTHI-induced otitis media. Genomic DNA fragments from NTHI strain 86-028NP were cloned upstream of the promoterless gfpmut3 gene. NTH

APA, Harvard, Vancouver, ISO, and other styles

21

Dagan, Ron, Eugene Leibovitz, Dan M. Fliss, et al. "Bacteriologic Efficacies of Oral Azithromycin and Oral Cefaclor in Treatment of Acute Otitis Media in Infants and Young Children." Antimicrobial Agents and Chemotherapy 44, no. 1 (2000): 43–50. http://dx.doi.org/10.1128/aac.44.1.43-50.2000.

Full text

Abstract:

ABSTRACT A prospective, open-label, randomized study was conducted in order to determine the bacteriologic efficacies of cefaclor and azithromycin in acute otitis media (AOM). Tympanocentesis was performed on entry into the study and 3 to 4 days after initiation of treatment. Bacteriologic failure after 3 to 4 days of treatment with both drugs occurred in a high proportion of culture-positive patients, especially in those in whom AOM was caused by Haemophilus influenzae(16 of 33 [53%] of those treated with azithromycin and 13 of 34 [52%] of those treated with cefaclor). Although a clear correl

APA, Harvard, Vancouver, ISO, and other styles

22

Iino, Yukiko, Naohiro Yoshida, Toshinori Kato, Keiko Kakizaki, Tetsuo Miyazawa, and Hiroyuki Kakuta. "Clinical effects of clarithromycin on persistent inflammation following Haemophilus influenzae-positive acute otitis media." Acta Oto-Laryngologica 135, no. 3 (2015): 217–25. http://dx.doi.org/10.3109/00016489.2014.975893.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Torretta, Sara, Paola Marchisio, Lorenzo Drago, et al. "Nasopharyngeal Biofilm-Producing Otopathogens in Children with Nonsevere Recurrent Acute Otitis Media." Otolaryngology–Head and Neck Surgery 146, no. 6 (2012): 991–96. http://dx.doi.org/10.1177/0194599812438169.

Full text

Abstract:

Objective. Bacterial biofilms have been detected in biopsies of the adenoid and middle ear mucosa of otitis-prone children and children with chronic middle otitis media. However, the invasiveness of biopsy makes it unsuitable for routine clinical practice, especially in pediatrics. This study aimed to investigate nasopharyngeal biofilm-producing otopathogens (BPOs) of nasopharyngeal swabs (NPS) in children with a history of nonsevere recurrent acute otitis media (RAOM) and healthy controls. Study Design. A cross-sectional study with planned data collection. Setting. University of Milan. Subjec

APA, Harvard, Vancouver, ISO, and other styles

24

Folino, Francesco, Luca Ruggiero, Pasquale Capaccio, et al. "Upper Respiratory Tract Microbiome and Otitis Media Intertalk: Lessons from the Literature." Journal of Clinical Medicine 9, no. 9 (2020): 2845. http://dx.doi.org/10.3390/jcm9092845.

Full text

Abstract:

Otitis media (OM) is one of the most common diseases occurring during childhood. Microbiological investigations concerning this topic have been primarily focused on the four classical otopathogens (Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes) mainly because most of the studies have been conducted with culture-dependent methods. In recent years, the introduction of culture-independent techniques has allowed high-throughput investigation of entire bacterial communities, leading to a better comprehension of the role of resident flora in healt

APA, Harvard, Vancouver, ISO, and other styles

25

Stone, Kimberley Clawson, Ron Dagan, Adriano Arguedas, et al. "Activity of Faropenem against Middle Ear Fluid Pathogens from Children with Acute Otitis Media in Costa Rica and Israel." Antimicrobial Agents and Chemotherapy 51, no. 6 (2007): 2230–35. http://dx.doi.org/10.1128/aac.00049-07.

Full text

Abstract:

ABSTRACT Faropenem was tested against 1,188 middle ear fluid pathogens from children in Israel and Costa Rica. Against Streptococcus pneumoniae and Haemophilus influenzae, faropenem was the most active β-lactam, with activity that was similar to or greater than of the other oral antimicrobial classes studied. Faropenem was also active against Moraxella catarrhalis and Streptococcus pyogenes.

APA, Harvard, Vancouver, ISO, and other styles

26

Novotny, Laura, Kenneth Brockman, Elaine Mokrzan, Joseph Jurcisek, and Lauren Bakaletz. "Biofilm Biology and Vaccine Strategies for Otitis Media Due to Nontypeable Haemophilus influenzae." Journal of Pediatric Infectious Diseases 14, no. 02 (2018): 069–78. http://dx.doi.org/10.1055/s-0038-1660818.

Full text

Abstract:

AbstractOtitis media (OM) is one of the most common diseases of childhood, and nontypeable Haemophilus influenzae (NTHI) is the predominant causative agent of chronic and recurrent OM, as well as OM for which treatment has failed. Moreover, NTHI is now as important a causative agent of acute OM as the pneumococcus. NTHI colonizes the human nasopharynx asymptomatically. However, upon perturbation of the innate and physical defenses of the airway by upper respiratory tract viral infection, NTHI can replicate, ascend the Eustachian tube, gain access to the normally sterile middle ear space, and c

APA, Harvard, Vancouver, ISO, and other styles

27

Liu, Keyi, Linlin Chen, Ravinder Kaur, and Michael E. Pichichero. "Transcriptome signature in young children with acute otitis media due to non-typeable Haemophilus influenzae." International Immunology 25, no. 6 (2013): 353–61. http://dx.doi.org/10.1093/intimm/dxs154.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Hotomi, Muneki, Jun Arai, Dewan S. Billal, et al. "Nontypeable Haemophilus influenzae isolated from intractable acute otitis media internalized into cultured human epithelial cells." Auris Nasus Larynx 37, no. 2 (2010): 137–44. http://dx.doi.org/10.1016/j.anl.2009.03.012.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Westman, Eva, Susanne Lundin, Ann Hermansson та Åsa Melhus. "β-Lactamase-Producing Nontypeable Haemophilus influenzae Fails To Protect Streptococcus pneumoniae from Amoxicillin during Experimental Acute Otitis Media". Antimicrobial Agents and Chemotherapy 48, № 9 (2004): 3536–42. http://dx.doi.org/10.1128/aac.48.9.3536-3542.2004.

Full text

Abstract:

ABSTRACT Acute otitis media (AOM) is the most common reason for outpatient antimicrobial therapy. Mixed infections pose a potential problem, since the first-line drug used for the treatment of AOM, amoxicillin, can be neutralized by β-lactamase-producing pathogens of the upper respiratory tract. To study the effects of a 5-day course of amoxicillin on a mixed middle ear infection, rats were challenged with Streptococcus pneumoniae alone or in combination with β-lactamase-producing nontypeable Haemophilus influenzae. Amoxicillin was introduced at the clinical peak of the infection. Local and sy

APA, Harvard, Vancouver, ISO, and other styles

30

Liu, Keyi, Janet Casey, and Michael Pichichero. "Serum Intercellular Adhesion Molecule 1 Variations in Young Children with Acute Otitis Media." Clinical and Vaccine Immunology 17, no. 12 (2010): 1909–16. http://dx.doi.org/10.1128/cvi.00194-10.

Full text

Abstract:

ABSTRACT Acute otitis media (AOM) is an inflammatory reaction in the middle ear, most often occurring in young children. Streptococcus pneumoniae, nontypeable Haemophilus influenzae, and Moraxella catarrhalis are the most common bacteria isolated. Intercellular adhesion molecule 1 (ICAM-1) is involved in the innate immune response to infection by microorganisms, in effective antigen presentation, and in subsequent T-cell activation. Here we prospectively studied levels of serum soluble ICAM-1 (sICAM-1) before, at the time of, and after antimicrobial treatment of AOM in a group of 138 children

APA, Harvard, Vancouver, ISO, and other styles

31

Almudevar, Anthony, and Michael E. Pichichero. "Haemophilus influenzae-protein D specific antibody correlate with protection against acute otitis media in young children." Vaccine 36, no. 9 (2018): 1133–35. http://dx.doi.org/10.1016/j.vaccine.2018.01.021.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Patel, Janak A., Barbara Reisner, Negar Vizirinia, Mary Owen, Tasnee Chonmaitree, and Virgil Howie. "Bacteriologic failure of amoxicillin-clavulanate in treatment of acute otitis media caused by nontypeable Haemophilus influenzae." Journal of Pediatrics 126, no. 5 (1995): 799–806. http://dx.doi.org/10.1016/s0022-3476(95)70415-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Whitby, P. W., K. E. Sim, D. J. Morton, J. A. Patel, and T. L. Stull. "Transcription of genes encoding iron and heme acquisition proteins of Haemophilus influenzae during acute otitis media." Infection and immunity 65, no. 11 (1997): 4696–700. http://dx.doi.org/10.1128/iai.65.11.4696-4700.1997.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Hotomi, Muneki, Keiji Fujihara, Akihiro Sakai, et al. "Antimicrobial resistance of Haemophilus influenzae isolated from the nasopharynx of Japanese children with acute otitis media." Acta Oto-Laryngologica 126, no. 3 (2006): 240–47. http://dx.doi.org/10.1080/00016480500314287.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Lopez, P., A. Sierra, M. A. Zapata, et al. "Non-typeable Haemophilus influenzae and Streptococcus pneumoniae: Primary causes of acute otitis media in Colombian children." International Journal of Infectious Diseases 14 (March 2010): e416-e417. http://dx.doi.org/10.1016/j.ijid.2010.02.547.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

LEIBOVITZ, EUGENE, ROBERT SATRAN, LOLITA PIGLANSKY, et al. "Can acute otitis media caused by Haemophilus influenzae be distinguished from that caused by Streptococcus pneumoniae?" Pediatric Infectious Disease Journal 22, no. 6 (2003): 509–14. http://dx.doi.org/10.1097/01.inf.0000069759.79176.e1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Pettigrew, M. M., B. Foxman, C. F. Marrs, and J. R. Gilsdorf. "Identification of the Lipooligosaccharide Biosynthesis Gene lic2B as a Putative Virulence Factor in Strains of Nontypeable Haemophilus influenzae That Cause Otitis Media." Infection and Immunity 70, no. 7 (2002): 3551–56. http://dx.doi.org/10.1128/iai.70.7.3551-3556.2002.

Full text

Abstract:

ABSTRACT Nontypeable (NT) strains of Haemophilus influenzae are an important cause of acute otitis media (OM). The pathogenic process by which NT H. influenzae strains cause OM is poorly understood. In order to identify specific virulence factors important for OM pathogenesis, genomic subtraction of the NT H. influenzae middle ear isolate G622 against H. influenzae strain Rd was conducted and the resulting subtraction products were used to screen a panel of H. influenzae isolates. Subtraction identified 36 PCR fragments unique to strain G622, which were used in a preliminary screen of 48 middl

APA, Harvard, Vancouver, ISO, and other styles

38

Setchanova, Lena, Iglika Stancheva, Diana Popova, Alexandra Alexandrova, and Ivan Mitov. "Bacterial Spectrum of Acute Otitis Media in Bulgarian Children during the 10-Valent Pneumococcal Conjugate Vaccine Era." Journal of Pediatric Infectious Diseases 15, no. 03 (2020): 135–43. http://dx.doi.org/10.1055/s-0040-1701647.

Full text

Abstract:

Abstract Objective The 10-valent pneumococcal conjugate vaccine (PCV10) was introduced in Bulgaria for universal childhood vaccination in 2010. The objective of this study was to describe bacterial pathogens responsible for acute otitis media (AOM) in children in the era of routine PCV10 immunization. Materials and Methods Middle ear fluid (MEF)/otorrhea or nasopharyngeal specimens were collected between May 2012 and April 2017 from 425 children aged < 12 years diagnosed with AOM; 71.5% of them were vaccinated. Capsular types of Streptococcus pneumoniae and Haemophilus influenzae and antimi

APA, Harvard, Vancouver, ISO, and other styles

39

Pettigrew, Melinda M., Alison S. Laufer, Janneane F. Gent, Yong Kong, Kristopher P. Fennie, and Joshua P. Metlay. "Upper Respiratory Tract Microbial Communities, Acute Otitis Media Pathogens, and Antibiotic Use in Healthy and Sick Children." Applied and Environmental Microbiology 78, no. 17 (2012): 6262–70. http://dx.doi.org/10.1128/aem.01051-12.

Full text

Abstract:

ABSTRACTThe composition of the upper respiratory tract microbial community may influence the risk for colonization by the acute otitis media (AOM) pathogensStreptococcus pneumoniae,Haemophilus influenzae, andMoraxella catarrhalis. We used culture-independent methods to describe upper respiratory tract microbial communities in healthy children and children with upper respiratory tract infection with and without concurrent AOM. Nasal swabs and data were collected in a cross-sectional study of 240 children between 6 months and 3 years of age. Swabs were cultured forS. pneumoniae, and real-time PC

APA, Harvard, Vancouver, ISO, and other styles

40

Magnuson, Karin, Ann Hermansson, Åsa Melhus, and Sten Hellström. "The Tympanic Membrane and Middle Ear Mucosa during Non-typeable Haemophilus influenzae and Haemophilus influenzae type b Acute Otitis Media: A Study in the Rat." Acta Oto-Laryngologica 117, no. 3 (1997): 396–405. http://dx.doi.org/10.3109/00016489709113412.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Sidorenko, S. V., and I. A. Dronov. "Amoxicillin in the treatment of acute respiratory infections in children: a dialogue between a microbiologist and a clinical pharmacologist." Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 65, no. 3 (2020): 169–76. http://dx.doi.org/10.21508/1027-4065-2020-65-3-169-176.

Full text

Abstract:

The article presents a modern view of amoxicillin in the treatment of acute respiratory infections in children from point of view of a microbiologist and clinical pharmacologist. Modern microbiological methods have changed the idea of the microbiota of the respiratory tract, however, the etiology of acute bacterial infections of the respiratory tract has not undergone significant changes – Streptococcus pneumoniae and Haemophilus influenzae are still the most common pathogens. Amoxicillin remains the drug of choice for most respiratory infections of bacterial etiology. Inhibitor-protected amin

APA, Harvard, Vancouver, ISO, and other styles

42

Kakuta, Risako, Hisakazu Yano, Hiroshi Hidaka, et al. "Molecular Epidemiology of Ampicillin-resistant Haemophilus influenzae Causing Acute Otitis Media in Japanese Infants and Young Children." Pediatric Infectious Disease Journal 35, no. 5 (2016): 501–6. http://dx.doi.org/10.1097/inf.0000000000001066.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Guan, Xiying, Shangyuan Jiang, Thomas W. Seale, Brooke M. Hitt, and Rong Z. Gan. "Morphological changes in the tympanic membrane associated with Haemophilus influenzae-induced acute otitis media in the chinchilla." International Journal of Pediatric Otorhinolaryngology 79, no. 9 (2015): 1462–71. http://dx.doi.org/10.1016/j.ijporl.2015.06.030.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Pichichero, Michael E., and Anthony Almudevar. "Serum cytokine biomarkers accurately predict presence of acute otitis media infection and recovery caused by Haemophilus influenzae." International Journal of Pediatric Otorhinolaryngology 83 (April 2016): 200–204. http://dx.doi.org/10.1016/j.ijporl.2016.02.007.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Chu, Trixy G., Daniel Rafael R. Cachola, Mary Agnes S. Regal, Agnes Cecille G. Llamas, Norberto V. Martinez, and Wilfredo R. Santos. "Pneumococcal Conjugate Vaccine (Non-Typeable Haemophilus influenzae (NTHi) Protein D, Diphtheria or Tetanus Toxoid Conjugates) in Prevention of Acute Otitis Media in Children: A Cohort Study." Philippine Journal of Otolaryngology-Head and Neck Surgery 31, no. 2 (2016): 13–15. http://dx.doi.org/10.32412/pjohns.v31i2.223.

Full text

Abstract:

Objective: To compare the incidence of acute otitis media among children aged 2 to 6 months old in Sampaloc, Manila who were previously given 3 doses of pneumococcal conjugate vaccine (Non-Typeable Haemophilus influenzae (NTHi) protein D, diphtheria or tetanus toxoid conjugates) and those who did not receive the vaccine, over a period of one year. Methods:  Study Design: Cohort Study Setting: Primary Health Center in Sampaloc, Manila, Philippines Participants: Medical records of well children aged 2 to 6 months were reviewed for inclusion. Participants were categorized

APA, Harvard, Vancouver, ISO, and other styles

46

Babl, Franz E., Stephen I. Pelton, and Zhong Li. "Experimental Acute Otitis Media Due to Nontypeable Haemophilus influenzae: Comparison of High and Low Azithromycin Doses with Placebo." Antimicrobial Agents and Chemotherapy 46, no. 7 (2002): 2194–99. http://dx.doi.org/10.1128/aac.46.7.2194-2199.2002.

Full text

Abstract:

ABSTRACT Treatment of acute otitis media (AOM) with azithromycin results in apparent clinical success, but tympanocentesis performed 4 to 6 days after initiation of therapy in children with nontypeable Haemophilus influenzae (NTHI) recovered from initial middle ear cultures demonstrates persistence of infection in more than 50% of episodes. We sought to determine the effect of azithromycin at different doses on the density of middle ear infection due to NTHI to provide additional understanding of this dichotomy between clinical and microbiologic outcome measures in AOM. In a chinchilla model o

APA, Harvard, Vancouver, ISO, and other styles

47

Spoială, Elena Lia, Gabriela Dumitrita Stanciu, Veronica Bild, Daniela Carmen Ababei, and Cristina Gavrilovici. "From Evidence to Clinical Guidelines in Antibiotic Treatment in Acute Otitis Media in Children." Antibiotics 10, no. 1 (2021): 52. http://dx.doi.org/10.3390/antibiotics10010052.

Full text

Abstract:

Acute otitis media (AOM) in children represents a public health concern, being one of the leading causes of health care visits and antibiotic prescriptions worldwide. The overall aim of this paper is to unravel the major current insights into the antibiotic treatment of AOM in children. Our approach is three-fold: 1. a preclinical evaluation of antibiotics in animal models of AOM stressing on the advantages of different species when testing for different schemes of antibiotics; 2. an overview on the new antimicrobial agents whose efficacy has been demonstrated in refractory cases of AOM in chi

APA, Harvard, Vancouver, ISO, and other styles

48

Pelton, S. I., M. Figueira, R. Albut, and D. Stalker. "Efficacy of Linezolid in Experimental Otitis Media." Antimicrobial Agents and Chemotherapy 44, no. 3 (2000): 654–57. http://dx.doi.org/10.1128/aac.44.3.654-657.2000.

Full text

Abstract:

ABSTRACT Therapy for otitis media (OM) due to resistant Streptococcus pneumoniae (MIC of penicillin, ≥2.0 μg/ml) is challenging. Linezolid, an oxazolidinone, represent a new class of antimicrobial agents with excellent in vitro activity against penicillin-resistantS. pneumoniae; however, in vitro activity against nontypeable Haemophilus influenzae (NTHI) is limited. We evaluated its efficacy against experimental acute OM due to a multidrug-resistant S. pneumoniae isolate and two isolates of NTHI. The chinchilla model was utilized to evaluate the efficacy of linezolid against experimental infec

APA, Harvard, Vancouver, ISO, and other styles

49

Marx, Michael A., and William K. Fant. "Cefuroxime Axetil." Drug Intelligence & Clinical Pharmacy 22, no. 9 (1988): 651–58. http://dx.doi.org/10.1177/106002808802200901.

Full text

Abstract:

Cefuroxime axetil is a orally active prodrug formulation of cefuroxime, which upon absorption undergoes immediate deesterification to free cefuroxime. Cefuroxime axetil offers an in vitro antibacterial spectrum against many gram-positive and some gram-negative organisms. Its beta-lactamase stability makes it useful in treating a variety of infections caused by beta-lactamase-producing strains of Haemophilus influenzae, Branhamella catarrhalis, and Staphylococcus aureus. Cefuroxime axetil has good activity against the Enterobacteriaceae and moderate activity against non-Bacteroides fragilis ana

APA, Harvard, Vancouver, ISO, and other styles

50

Clarke, Christopher, Lauren O. Bakaletz, Javier Ruiz-Guiñazú, Dorota Borys, and Tomas Mrkvan. "Impact of protein D-containing pneumococcal conjugate vaccines on non-typeable Haemophilus influenzae acute otitis media and carriage." Expert Review of Vaccines 16, no. 7 (2017): 751–64. http://dx.doi.org/10.1080/14760584.2017.1333905.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!