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Journal articles on the topic 'Acute pyrexia'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Tong, Giang, Nalina N. A. von Garlen, Sylvia J. Wowro, et al. "Post-TTM Rebound Pyrexia after Ischemia-Reperfusion Injury Results in Sterile Inflammation and Apoptosis in Cardiomyocytes." Mediators of Inflammation 2019 (November 21, 2019): 1–10. http://dx.doi.org/10.1155/2019/6431957.

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Introduction. Fever is frequently observed after acute ischemic events and is associated with poor outcome and higher mortality. Targeted temperature management (TTM) is recommended for neuroprotection in comatose cardiac arrest survivors, but pyrexia after rewarming is proven to be detrimental in clinical trials. However, the cellular mechanisms and kinetics of post-TTM rebound pyrexia remain to be elucidated. Therefore, we investigated the effects of cooling and post-TTM pyrexia on the inflammatory response and apoptosis in a cardiomyocyte ischemia-reperfusion (IR) injury model. Methods. HL-

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2

Sirohi, Brijesh, and Rakesh Sagar. "Antipyretic Activity of Hydroalcoholic Extract of Dactylorhiza Hatagirea Roots & Lavandula Stoechas Flowers on Brewer’s Yeast Induced Pyrexia in Wistar Rats." Journal of Drug Delivery and Therapeutics 9, no. 4-A (2019): 701–4. http://dx.doi.org/10.22270/jddt.v9i4-a.3553.

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Medicinal plants are the part and parcel of human society to combat against different diseases from the dawn of human civilization. According to World Health Organization, approximately 85% population of the developing countries are facing difficulties to afford synthetic drugs and are relying on traditional medicines mainly of plant origin in order to maintain their primary health care needs. Plants are being used in various disorders. The present pharmacological investigation was undertaken to study the anti-pyretic activity of hydroalcoholic extract of D. hatagirea roots (HEDH) & L. sto

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Bharathi R, Poovizhi, Manohar V R, Mohandas Rai, and Athiyamaan M S. "Evaluation of the Antipyretic and Anti-Inflammatory Potential of Aqueous Fruit Pulp Extract of Terminalia bellirica." Biomedical and Pharmacology Journal 16, no. 1 (2023): 295–304. http://dx.doi.org/10.13005/bpj/2611.

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Many fatal diseases have inflammation and fever as clinical symptoms. NSAIDs are the drug of choice for both of these symptoms. But they cause numerous adverse drug reactions including the gastrointestinal, renal and cardiovascular systems. Herbal medicines are known for their efficacy and lack of adverse reactions. So the search for herbal remedies is always on. Terminalia bellirica fruit pulp is used to alleviate a lot of health conditions. Hence this study looked at the antipyretic and anti-inflammatory activities of aqueous extract of Terminalia bellirica fruit pulp in rodents. The carrage

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Ibrahimi, Alfred, Saimir Kuci, Ervin Bejko, et al. "Management Strategy of Hyperthermic State in Critically Ill Patient." Albanian Journal of Trauma and Emergency Surgery 2, no. 2 (2018): 182–88. http://dx.doi.org/10.32391/ajtes.v2i2.24.

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Pyrexia is a protective physiologic response of the body against external and internal aggression. Temperature control is safe in and effective in septic shock but remain controversial in sepsis. Treating pyrexia to reduce oxygen consumption appears to have beneficial in cardiac arrest, low cardiac output and acute brain injury. Multiple therapeutic options are available for managing pyrexia, with precise targeted temperaturemanagement. Notably, the use of pharmacotherapy versus surface cooling has not been shown to be advantageous. When these two-therapy failed to control the extra-corporal m

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Bahl, Suhani, Priya Mohan Babu, Florin Capatana, Ishrat Khan, Mohamed Adlan, and Lakdasa D. K. E. Premawardhana. "Sub-Acute Thyroiditis Presenting as Pyrexia of Uknown Origin." Journal of the Endocrine Society 5, Supplement_1 (2021): A956. http://dx.doi.org/10.1210/jendso/bvab048.1953.

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Abstract Introduction: Pyrexia of unknown origin (PUO) is often a diagnostic challenge. Common causes currently reported include non-infectious inflammatory disorders (NIID) (30.6%), infections (23.1%), malignancy (10.7%) and miscellaneous (12.4%). However, 23.1% remain undiagnosed despite extensive investigations. Fever is a component of subacute thyroiditis (SAT) in 28-83% of subjects reported in the literature. But its presentation as a PUO is reported only in a handful of subjects. Case Presentation: A 71-year-old Asian male presented with evening fevers of 2-3 weeks duration. He had no ac

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Ganesan, Subramanian, Arif Khan, Nahin Hussain, and Lyvia Dabydeen. "Acute disseminated encephalomyelitis presenting as pyrexia of unknown origin." Journal of Pediatric Neurosciences 7, no. 2 (2012): 148. http://dx.doi.org/10.4103/1817-1745.102584.

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7

Li, Gang, Xiao-yun Xu, Yue Wang, et al. "Mild-to-Moderate Neurogenic Pyrexia in Acute Cerebral Infarction." European Neurology 65, no. 2 (2011): 94–98. http://dx.doi.org/10.1159/000322803.

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8

Landray, M. J., T. Ringrose, R. E. Ferner, and I. R. Arnold. "Pyrexia, anaemia and acute renal failure secondary to omeprazole." Postgraduate Medical Journal 74, no. 873 (1998): 416–18. http://dx.doi.org/10.1136/pgmj.74.873.416.

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9

Luman, W., W. G. Middleton, and R. S. Gray. "Acute Myelocytic Leukaemia Presenting as Anergic Pulmonary Tuberculosis." Scottish Medical Journal 39, no. 4 (1994): 116–17. http://dx.doi.org/10.1177/003693309403900407.

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This case report describes a patient with anergic pulmonary tuberculosis who presented with pyrexia of unknown origin and vasculitis. He did not exhibit any pulmonary symptoms at his initial presentation and developed acute myelocytic leukaemia, a recognised association, during the subsequent course of his illness.

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10

Pappa, Efthymia, Marina Gkeka, Asimina Protogerou, Leonidas Marinos, Chariclia Loupa, and Constantinos Christopoulos. "Case Report: Acute amyopathic dermatomyositis presenting with isolated facial edema." F1000Research 7 (January 16, 2018): 60. http://dx.doi.org/10.12688/f1000research.13604.1.

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A 45-year-old Asian man presented with acute-onset periorbital and facial edema associated with pyrexia. Muscle weakness was absent. Initial laboratory investigations showed an inflammatory reaction, while screening for infections was negative. Serum muscle enzyme levels were normal. He was hospitalized and treated empirically with antibiotics and corticosteroids, pending the result of facial skin and muscle biopsy. He showed a good clinical and laboratory response but an attempt to discontinue corticosteroids led to a prompt relapse of facial edema and pyrexia, associated with rising laborato

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11

Akhter, Rumana, Md Aminul Haque, Mohiuddin Ahmed Bhuiyan, and Mohamad Shahriar. "In vivo Pharmacological investigation of leaf of Polygonum hydropiper (L.)." Dhaka University Journal of Pharmaceutical Sciences 12, no. 2 (2014): 165–69. http://dx.doi.org/10.3329/dujps.v12i2.17619.

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The present study was planned to evaluate the anti-nociceptive, gastro intestinal motility, anti-pyretic and acute toxicity studies of leaf extract of Polygonum hydropiper leaves in albino mice following oral administration. The results showed that the anti-nociceptive activity in the scale of ethanol > n-hexane > petroleum ether > chloroform > methanol extract showed a significant result compared to diclofenac sodium. Chloroform extract showed significant results on gastro intestinal motility test. Ethanol & chloroform extracts showed considerable reduction of temperature at h

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12

Jha, A., and R. Sarda. "Value of Bone marrow Examination in Pyrexia of unknown origin." Journal of Pathology of Nepal 3, no. 6 (2013): 447–51. http://dx.doi.org/10.3126/jpn.v3i6.8991.

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Background: Pyrexia of unknown origin is a common diagnostic dilemma. Series of diagnostic modalities are required to arrive at diagnosis. Bone marrow examination is one of the common tests implicated in the diagnosis in combination with other diagnostic modalities. Present study has attempted to explore the causes of pyrexia of unknown origin based on bone marrow morphological study. Materials and Methods: In a one year prospective study conducted at Manipal Teaching Hospital, Pokhara, Nepal; bone marrow aspiration and biopsy was performed and evaluated morphologically, in 57 patients fulfill

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Obuaya, Chi-Chi, Gayathri Thivyaa Gangatharan, and Efthimia Karra. "Brucella-Induced Acute Psychosis: A Novel Cause of Acute Psychosis." Case Reports in Infectious Diseases 2021 (March 4, 2021): 1–4. http://dx.doi.org/10.1155/2021/6649717.

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Background. Infections have long been linked to psychosis and categorised within “secondary” psychoses. To date, there have been few reports of psychosis linked to brucellosis. This case report aims to present one such case. Case Presentation. A 31-year-old man was admitted to a general hospital with pyrexia, severe right upper quadrant pain, and an acute psychosis following a two-week holiday in South East Asia and the Mediterranean. Serological tests revealed that he had brucellosis. Following antibiotic treatment, the psychotic symptoms abated and he was discharged within ten days of hospit

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Pappa, Efthymia, Marina Gkeka, Asimina Protogerou, Leonidas Marinos, Chariclia Loupa, and Constantinos Christopoulos. "Case Report: Clinically amyopathic dermatomyositis presenting acutely with isolated facial edema." F1000Research 7 (March 26, 2018): 60. http://dx.doi.org/10.12688/f1000research.13604.2.

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A 45-year-old Asian man presented with acute-onset periorbital and facial edema associated with pyrexia. Muscle weakness was absent. Initial laboratory investigations showed an inflammatory reaction, while screening for infections was negative. Serum muscle enzyme levels were normal. He was hospitalized and treated empirically with antibiotics and corticosteroids, pending the result of facial skin and muscle biopsy. He showed a good clinical and laboratory response but an attempt to discontinue corticosteroids led to a prompt relapse of facial edema and pyrexia, associated with rising laborato

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15

Khanna, Divya, Ajoy Bardhan, Adrian Heagerty, and Natasha Harper. "SG15 A topical matter: iatrogenic adrenal crisis following excessive prescription corticosteroid use." British Journal of Dermatology 191, Supplement_1 (2024): i188. http://dx.doi.org/10.1093/bjd/ljae090.397.

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Abstract A 39-year-old man with intermediate junctional epidermolysis bullosa (EB) was admitted with a 2-week history of nausea, vomiting, diarrhoea, weakness, loss of appetite and abdominal pain. He described worsening pain within his chronic wounds, which were widespread, crusted and producing extensive green exudate. On admission, he was hypotensive, tachycardic and pyrexial. Investigations showed anaemia (haemoglobin 86 g L−1), hyponatraemia (132 mmol L−1), hypokalaemia (3.3 mmol L−1), raised lactate (3.29 mmol L−1), raised C-reactive protein (263 mg L−1), and leucocytosis (white cell coun

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16

Siddiqui, Riyaz Ahmed, Tanaji R. Shende, Y. Dhoble, and Archana S. Borkar. "Antibiotic trends in acute febrile illness." International Journal of Basic & Clinical Pharmacology 6, no. 2 (2017): 334. http://dx.doi.org/10.18203/2319-2003.ijbcp20170325.

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Background: Acute febrile illness has various etiologies. Different antimicrobials are used for different causes of fever to treat and there are interpersonal variations in prescription of antimicrobials. Therefore this study aims at to analyze the trends in the antimicrobial prescription in patients of acute febrile illness due to various etiologies in the medicine department of a tertiary care hospital.Methods: It is a record based observational study that was carried out at NKP salve institute of medical sciences and RC, Nagpur. 200 case record files of patients admitted with a diagnosis of

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17

Gustafson, BW, and LJ DeBowes. "Tularemia in a dog." Journal of the American Animal Hospital Association 32, no. 4 (1996): 339–41. http://dx.doi.org/10.5326/15473317-32-4-339.

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A 13-month-old German shepherd dog was presented with acute onset of anorexia, pyrexia, lymphadenopathy, and tonsillitis. Tularemia was diagnosed based on a greater-than-fourfold increase in antiFrancisella tularensis antibody titers over a three-week period. The disease was self-limiting, and clinical signs resolved within five days with only supportive therapy.

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18

Mrinmoy, Basak, Laskar Ahmed Moksood, and Goswami Priyanka. "Evaluation of Anti-Oxidant and Anti-Pyretic Activity of Fruit of Garcenia Padunculata." Asian Journal of Pharmaceutical Research and Development 8, no. 3 (2020): 77–80. http://dx.doi.org/10.22270/ajprd.v8i3.751.

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Most of the synthetic drugs used at present as analgesic and anti-inflammatory agents cause many side effects and toxic effects. Many medicines of plant origin with analgesic and anti-inflammatory activity have been used since long time without adverse effects. The purpose of the study was to explore the anti-pyretic and anti-oxidant activity of fruits of Garcinia pedunculata. The fruit of G. pedunculatawas collected from Shillong, Meghalaya and extraction is done by using methanol as a solvent. The methanol extract shows the presence of carbohydrate, glycoside, alkaloids, phenol and flavonoid

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19

Malavera, Alejandra, Shoujiang You, Danni Zheng, Candice Delcourt, and Craig S. Anderson. "Prognostic significance of early pyrexia in acute intracerebral haemorrhage: The INTERACT2 study." Journal of the Neurological Sciences 423 (April 2021): 117364. http://dx.doi.org/10.1016/j.jns.2021.117364.

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20

Dittner, Claudia, Erik Lindsund, Barbara Cannon, and Jan Nedergaard. "At thermoneutrality, acute thyroxine-induced thermogenesis and pyrexia are independent of UCP1." Molecular Metabolism 25 (July 2019): 20–34. http://dx.doi.org/10.1016/j.molmet.2019.05.005.

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21

Stocchetti, N. "Impact of pyrexia on neurochemistry and cerebral oxygenation after acute brain injury." Journal of Neurology, Neurosurgery & Psychiatry 76, no. 8 (2005): 1135–39. http://dx.doi.org/10.1136/jnnp.2004.041269.

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22

Aslam, Bilal, Asif Hussain, Muhammad Usman Bari, et al. "Anti-Pyretic, Analgesic, and Anti-Inflammatory Activities of Meloxicam and Curcumin Co-Encapsulated PLGA Nanoparticles in Acute Experimental Models." Metabolites 13, no. 8 (2023): 935. http://dx.doi.org/10.3390/metabo13080935.

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Herein, we evaluated the in vivo effects of meloxicam and curcumin co-encapsulated PLGA nanoparticles in experimental acute models of pyrexia, nociception, and inflammation. Seven groups (n = 6) were designed for each investigation and pretreated intraperitoneally (i.p.): the control group, meloxicam (4 mg/kg b.w.), curcumin (15 mg/kg b.w.), and equivalent content containing PLGA capped nanoparticles of meloxicam (Mlx-NP) and curcumin (Cur-NP) alone and in combination (Mlx-Cur-NP; at two doses). The results showed that PLGA encapsulation significantly (p ≤ 0.05) improved the in vivo activities

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23

Tarinita Devi, Leisangthem, Mayanglambam Medhabati Devi, Florence Lalvarmawi, and Swagata Datta. "ANTI-PYRETIC AND ANTI-INFLAMMATORY ACTIVITY OF AQUEOUS EXTRACT OFSOLANUM XANTHOCARPUM BERRIES IN SUITABLE ANIMAL MODELS." International Journal of Advanced Research 9, no. 11 (2021): 954–59. http://dx.doi.org/10.21474/ijar01/13827.

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Background: Use of traditional medicines for treating various diseases have become a topic of global importance because of their safety, less side effects and cost-effectiveness. The present study was undertaken to evaluate the anti-pyretic and anti-inflammatory activity of aqueous extract of Solanum xanthocarpum berries (SXB) in suitable animal models. Methods: Anti-pyretic activity was assessed by dried yeast induced pyrexia in rats. Anti-inflammatory activity was evaluated using carrageenan induced paw oedema in rats. Three doses of the plant extract (500, 1000 and 1500 mg/kg) prepared by d

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Bherji, Sneha, M. Ganga Raju, and Namile Divya. "Evaluation of Antipyretic and Anti-inflammatory Activity of Aqueous Extract of Leptadenia Reticulata in Animal Models." Journal of Natural Remedies 16, no. 2 (2016): 40. http://dx.doi.org/10.18311/jnr/2016/468.

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<strong>Objective:</strong> To study the antipyretic and anti-inflammatory effects of the Aqueous Extract of <em>Leptadenia Reticulata</em> (AELR) in different animal models. <strong>Materials and Methods</strong>: Acute toxicity studies were performed and extract was found to be safe upto 2000 mg/kg. Two doses were selected for the "evaluation of antipyretic and anti-inflammatory activity of aqueous extract of <em>Leptadenia reticulata</em> in animal models" i.e 200 mg/kg and 400 mg/kg b. w. Antipyretic activity was evaluated using baker's yeast

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Sharma, Raghava. "PROLONGED PYREXIA WITH ACUTE RENAL INSULT - UNRAVELING THE PUZZLE AND SOLVING THE ENIGMA." Journal of Health and Allied Sciences NU 04, no. 02 (2014): 129–32. http://dx.doi.org/10.1055/s-0040-1703781.

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Abstract:A middle aged man with prolonged pyrexia was referred to us with a diagnosis of FUO (Fever of unknown origin). He was evaluated by various investigations and a diagnosis of Tuberculosis was established. On anti tubercular treatment (ATT) he developed complication of acute renal injury –non oliguric renal failure, from which he recovered fully after the puzzle was successfully solved & managed accordingly. Even though he was proved to have rifampicin induced acute intersticial nephritis(AIN) by biopsy , he had varied & unconventional presentation like without oliguria, without

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Davies, M., M. Nanda Kumar, V. Shetty, and P. Mitchell. "Henoch–Schönlein purpura as a rare cause of an acute abdomen." Annals of The Royal College of Surgeons of England 99, no. 2 (2017): e88-e90. http://dx.doi.org/10.1308/rcsann.2016.0359.

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A 52-year-old man presented with a purpuric rash affecting his legs and hypertension. He was diagnosed with Henoch–Schönlein purpura and discharged with non-steroidal anti-inflammatory drugs. Three weeks later, he presented again with loss of appetite and vomiting before developing abdominal pain with pyrexia of 38.5°C and rigors. On examination, he was hypotensive with a distended abdomen and a national early warning score of 6. Computed tomography revealed enteropathy of Henoch–Schönlein purpura. The patient deteriorated and went for an emergency laparotomy, where 30cm of ischaemic small bow

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Alabi, B. Sulyman, A. Aishat Abdulkarim, Olatoke Fatai, and Suleiman O. Abdulmajeed. "Prevalence of acute otitis media among children with pyrexia in a Nigerian hospital." Auris Nasus Larynx 36, no. 5 (2009): 532–35. http://dx.doi.org/10.1016/j.anl.2008.12.007.

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Mahnashi, Mater H., Yahya S. Alqahtani, Bandar A. Alyami, et al. "GC-MS Analysis and Various In Vitro and In Vivo Pharmacological Potential of Habenaria plantaginea Lindl." Evidence-Based Complementary and Alternative Medicine 2022 (March 31, 2022): 1–13. http://dx.doi.org/10.1155/2022/7921408.

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Background. The current study aims to give a scientific origin for employing Habenaria plantaginea Lindl. as a potential candidate against nociception, inflammation, and pyrexia. The pharmacological studies were performed on crude extract and subfractions. In the gas chromatography-mass spectroscopy analysis, a total of 21 compounds were identified. The plant samples were displayed for in vitro anti-inflammatory potentials. The observed IC50 for chloroform against cyclooxygenase-2 and 5-lipoxygenase enzymes was 33.81 and 26.74 μg/mL, respectively. The in vivo activities were prerequisites with

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Doma, Ibrahim, Ibrahim Haruna, and Abdullahi Hamza. "Antipyretic and Antinociceptive Effect of the Methanol Leaf Extract of Ficus asperifolia in Murine Models." Journal of Current Biomedical Research 4, no. 1, January-February (2024): 1436–53. http://dx.doi.org/10.54117/jcbr.v4i1.2.

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Pyrexia occurs as a result of the resetting of the hypothalamic set-point. Non steroidal anti-inflammatory drugs used for the treatment of fever and related illnesses are associated with side effects including gastrointestinal irritation, bleeding, ulcers and perforation. In traditional medicine, many plants have been found to possess antipyretic activity. Ficus asperifolia (Miq), family Moraceae has been traditionally used to treat pain and fevers. The aim of the study was thus to evaluate the antipyretic and antinociceptive activity of the methanol leaf extract of Ficus asperifolia (FME) in

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Murrant, N. J., J. A. CooK, and S. H. Murch. "Acute ENT admission in Kawasaki disease." Journal of Laryngology & Otology 104, no. 7 (1990): 581–84. http://dx.doi.org/10.1017/s0022215100113222.

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AbstractKawasaki disease (mucocutaneous lymph node syndrome) is an acute vasculitis of childhood carrying a 1–2 per cent mortality from cardiovasular complications. Despite the extensive literature on Kawasaki disease in paediatric journals, there has been a paucity of documentation in the otolaryngological literature. This is despite the fact that Kawasaki disease may present as an otolaryngological emergency before the diagnosis is established. We describe three cases of Kawasaki disease, all of which presented to the ENT department of this hospital within a period of two months. These cases

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Evans, P. J., B. R. Leaker, W. R. McNabb, and R. R. Lewis. "Accuracy of Reagent Strip Testing for Urinary Tract Infection in the Elderly." Journal of the Royal Society of Medicine 84, no. 10 (1991): 598–99. http://dx.doi.org/10.1177/014107689108401009.

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The accuracy of reagent strip testing for urinary tract infection (UTI) was assessed in 100 elderly patients (50 acute patients admitted to hospital and 50 attending the day hospital). Reagent strip sensitivities were: Acute patients – urinary nitrite 83%, blood 67%, protein 72% and leucocytes 72%, and day hospital patients — urinary nitrite 90%, blood 65%, protein 30% and leucocytes 60%. Urinary nitrite specificities were 100% for both groups of patients. Only 28% of patients with a UTI had specific symptoms of the infection; pyrexia and a raised WBC also proved poor indicators. Urinary nitri

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Kalra, Lalit, Craig J. Smith, John Hodsoll, Andy Vail, Saddif Irshad, and Dulka Manawadu. "Elevated C-reactive protein increases diagnostic accuracy of algorithm-defined stroke-associated pneumonia in afebrile patients." International Journal of Stroke 14, no. 2 (2018): 167–73. http://dx.doi.org/10.1177/1747493018798527.

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Background and aim Pyrexia-dependent clinical algorithms may under or overdiagnose stroke-associated pneumonia. This study investigates whether inclusion of elevated C-reactive protein as a criterion improves diagnosis. Methods The contribution of C-reactive protein ≥30 mg/l as an additional criterion to a Centers for Disease Control and Prevention-based algorithm incorporating pyrexia with chest signs and leukocytosis and/or chest infiltrates to diagnose stroke-associated pneumonia was assessed in 1088 acute stroke patients from 37 UK stroke units. The sensitivity, specificity, and positive p

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Woolley, Angharad K., Neil A. Hedger, and Rithesh P. Veettil. "https://staging.acutemedjournal.co.uk/problem-based-review-the-patient-with-acute-monoarthritis/." Acute Medicine Journal 12, no. 2 (2013): 107–10. http://dx.doi.org/10.52964/amja.0299.

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Pyrexia of unknown origin (PUO) is a frequent presentation to the Acute Medical Unit, and is a source of significant morbidity, both the psychological burden of an uncertain diagnosis and prognosis and untreated complications of the underlying pathology. We present a problem based review of the management of PUO, illustrated by a patient who recently presented to our unit with fever and systemic malaise after returning from abroad and in whom no cause could be found for more than two months. We describe a structured approach making use of complex modern techniques such as Positron Emission Tom

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Dr., Tapas Ghosh, Arpan Dey Dr., and Sudipto Konar Dr. "Spectrum of Clinical Presentations in Different Variants of Acute Appendicitis." International Journal of Research and Review 6, no. 5 (2019): 364–69. https://doi.org/10.5281/zenodo.3989507.

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Acute appendicitis is the commonest abdominal emergency. It is mainly a disease of teenagers and young adults affecting the most productive section of the population. So prolongation of morbidity due to negative laparotomy is unwanted and at the same time delay in diagnosis of acute appendicitis is apprehended. The present study was conducted on 75 histologically proved cases of acute appendicitis. Detailed clinical, morphological and histopathological features were studied. Abdominal pain was present in all patients and right iliac fossa was the usual site of abdominal pain. A significant num

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Kabir, Muhib Muhammed, Mehnaz Kabir, Tarim Mahmood, and M. M. Faniqul Islam. "Pyrexia of Unknown Origin Caused by Toxoplasmosis: A Rare Case Report." European Journal of Medical and Health Research 3, no. 3 (2025): 211–14. https://doi.org/10.59324/ejmhr.2025.3(3).31.

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Introduction: Toxoplasma gondii is an obligate intracellular parasite that causes infection in up to one-third of the world's population. It is essential to document every such case for the education of the clinicians for better treatment of the affected individuals. Case presentation: We present a 50-year-old individual of Bangladeshi lineage who presented as pyrexia of unknown origin who was ultimately diagnosed as acute Toxoplasmosis. The patient was treated conservatively with a range of antibiotics, he gradually became clinically and hemodynamically stable and was released. Conclusion: Th

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George, Jayan, Samuel Besant, Trevor Cleveland, and Ahmed Al-Mukhtar. "Pseudoaneurysm of the Inferior Pancreaticoduodenal Artery Due to Cholecystitis." Reports 2, no. 1 (2019): 11. http://dx.doi.org/10.3390/reports2010011.

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Inferior pancreaticoduodenal artery pseudoaneurysms and aneurysms are a rare occurrence, comprising of approximately 10% of visceral artery aneurysms and pseudoaneurysms. The cause is normally due to trauma, iatrogenic or pancreatitis. We present a case of a patient re-presenting to hospital following treatment of acute cholecystitis with epigastric pain, dysphagia, pyrexia, nausea, vomiting and an acute kidney injury. Following cholecystostomy, intravenous fluids and conservative treatment for her symptoms, she failed to improve significantly and was found to have a 6 mm pseudoaneurysm of the

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Jabeen, Shehneela, Muhammad Farooq, Samina Naeem, et al. "The role of bone marrow biopsy in patients with pyrexia of unknown origin." Journal of Fatima Jinnah Medical University 16, no. 1 (2022): 12–15. http://dx.doi.org/10.37018/rnmi7117.

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Background: Pyrexia of unknown origin (PUO) is a major complication which remains undiagnosed. Different diagnostic test were used to arrive at final investigation. Bone marrow biopsy (BMB) plays a vital role in diagnosis of PUO. The objective of current study was to determine the role of bone biopsy in diagnosing various types of causes of pyrexia of unknown origin. Patients and methods: A prospective cross-sectional study was conducted from 1st September 2018 to 28th February 2019 at Department of Hematology, Combined Military Hospital Lahore, Pakistan. The data of 120 patients who wer

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Duromola, Kehinde Micheal, Anisah Yahya, Umoru Odoje Raymond, et al. "Acute abdomen secondary to ovarian tumour incarcerated in an umbilical hernia: A case report." Journal of West African College of Surgeons 14, no. 3 (2024): 355–57. http://dx.doi.org/10.4103/jwas.jwas_138_23.

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Abstract Acute abdomen due to incarcerated umbilical hernia is a surgical emergency. Acute abdomen secondary to gynaecological conditions is not uncommon. However, acute abdomen due to incarceration of a gynaecological tumour in an umbilical hernia is rare. A 25-year-old nullipara was admitted to the accident and emergency unit with a history of recurrent lower abdominal pain and abdominal swelling for 4 weeks. Pain worsened within the last 24 h necessitating presentation. Examination revealed a low-grade pyrexia, tachypnoea, an umbilical swelling with generalised abdominal tenderness, and a p

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Panduranga, Prashanth. "Aortic Root Abscess Presenting as Pyrexia of Unknown Origin and the Importance of Echocardiography." Case Reports in Critical Care 2013 (2013): 1–3. http://dx.doi.org/10.1155/2013/636519.

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Aortic root abscess in patients with aortic endocarditis is not uncommon. Aortic root abscess may cause persistent sepsis, worsening heart failure, conduction abnormalities, fistula formation, and an increased need for surgery. We present a young patient with aortic root abscess presenting as pyrexia of unknown origin. She had acute severe aortic and mitral regurgitation which produced very soft murmurs that were easily missed. This report reiterates that a high index of suspicion is needed in suspecting valvular endocarditis as well as a comprehensive transthoracic and transesophageal echocar

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Najdenkina, S. N., and M. K. Ermakova. "Fever: current view on its significance in the COVID-19 era and the people’s attitude to this symptom." Russian Journal of Immunology 28, no. 2 (2025): 315–20. https://doi.org/10.46235/1028-7221-17048-fcv.

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Our purpose was to evaluate the scientific data on occurrence of fever in the infectious conditions as well as studying peculiar features of fever in children at pediatric unit with assessment of attitude towards pyrexia among general population. Fever is a general response to infection which occurs across warm- and cold-blooded vertebrates for over 600 million years of evolution. The response to fever is mediated by integrated physiological and neural circuitries and provides a survival advantage during infection. The world experience in fever studies shows an ambiguous effectiveness of comba

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Olorukooba, Amina B., Ferhat Khan, Yahya M. Sani, Asmau N. Hamza, and Aisha O. Musa. "Analgesic, anti-inflammatory and antipyretic studies on the residual aqueous fraction of Uapaca togoensis (Pax) stem bark in rodents." Journal of Pharmacy & Bioresources 17, no. 2 (2021): 189–99. http://dx.doi.org/10.4314/jpb.v17i2.13.

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Uapaca togoensis Pax. (Euphorbiaceae) is used in traditional medicine to treat several diseases including pain, inflammation and fever. This study investigated analgesic, anti-inflammatory and anti-pyretic effects of the residual aqueous fraction of the plant. Preliminary phytochemical screening and acute toxicity studies were conducted. Analgesic activity was evaluated using acetic acid-induced writhing, hot plate and formalin-induced pain tests at doses of 250, 500 and 1000 mg/kg, p.o. Anti-inflammatory and antipyretic activities were investigated using carrageenaninduced paw edema and Brewe

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Dhar, Srikant Kumar, Sobhitendu Kabi, Chandan Das, et al. "CLINICAL SPECTRUM OF SCRUB TYPHUS IN A TERTIARY CARE HOSPITAL AT EASTERN INDIA." Asian Journal of Pharmaceutical and Clinical Research 11, no. 5 (2018): 351. http://dx.doi.org/10.22159/ajpcr.2018.v11i5.24668.

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Objective: Our hospital, tertiary care hospital in the capital of the state of Odisha, had been witnessing pyrexia of unknown origin, associated with breathlessness, renal, and liver impairment, which did not respond to high antibiotics but to doxycycline; therefore, the present study was undertaken to identify whether scrub typhus is the etiological agent, and thereafter, their characteristic features were further evaluated as an effort in supporting its diagnoses and treating patients accordingly.Methods: A total of 65 adult patients (age >15 years) admitted with pyrexia between April 201

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Adhikari, Swastika, Ashish Lal Shrestha, Sanjay Raj Thapa, and Amrit Ghimire. "A Rare Cause of Acute Hepatopancreatitis in a Nepalese Teen." Case Reports in Pediatrics 2018 (November 21, 2018): 1–6. http://dx.doi.org/10.1155/2018/8456503.

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Background. Acute pancreatitis (AP) coexisting with acute hepatitis (AH) in children is uncommon. Moreover, a single bacterial cause explaining both the complications is even rarer. Despite familiarity with the usual presentation of enteric fever, atypical presentations can go unnoticed. Case Presentation. A 16-year-old previously healthy male presented to the emergency unit with recurrent swinging pyrexia, abdominal symptoms, and jaundice for a week. Blood work-up revealed deranged liver function tests (LFTs) and elevated pancreatic enzymes. Further assessment with imaging made a diagnosis of

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Moniruddin, ABM, Salma Chowdhury, Tanvirul Hasan, Baikaly Ferdous, and Md Rashed Khan. "Atypical Presentations of Appendicitis." KYAMC Journal 12, no. 2 (2021): 101–6. http://dx.doi.org/10.3329/kyamcj.v12i2.55444.

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Appendicitis has its acute, subacute, recurrent and chronic forms. Appendicitis is commonly predisposed to and precipitated by a single or a combination of multiple discrete factors like obstruction of lumen, ischemia from thromboembolic episodes, infection or idiopathic etc. Typically, it starts as umbilical or peri-umbilical or midline abdominal dull aching pain that soon gets localized in the right iliac region. Movements worsen the pain. Other typical features include nausea, vomiting, anorexia, pyrexia, preference to lie down with or without curling up, chills, constipation, diarrhea, fev

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Saeed, Zahid. "ACUTE APPENDICITIS;." Professional Medical Journal 21, no. 06 (2014): 1139–43. http://dx.doi.org/10.29309/tpmj/2014.21.06.2246.

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Background: Acute appendicitis is the commonest cause of acute abdomen presenting in emergency room, which is mainly diagnosed on clinical grounds. Objective: To determine the diagnostic accuracy in patient of acute appendicitis and to review the pathological diagnosis. Material and Method: A retrospective study was conducted at PNS SHIFA hospital at Karachi; from May 2012 to April 2013. A total of 120 patients were included in the study who presented with acute abdomen and clinically diagnosed as acute appendicitis. Emergency appendectomy was done in all consecutive subjects and intra operati

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Ravishankar, Chintu, P. Priya, M. Mini, et al. "First confirmed occurrence of classical swine fever in Kerala state, India." Journal of Swine Health and Production 15, no. 3 (2007): 156–59. http://dx.doi.org/10.54846/jshap/522.

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This case study describes the first detection of classical swine fever (CSF) in Kerala state, India. Two cases of acute mortality in small-scale pig farming units were investigated. In both cases, affected pigs had been maintained on uncooked waste and were not vaccinated against CSF. Anorexia, hyperaemia of the ears, pyrexia, and convulsions were the primary clinical signs observed in both cases. Clinical signs exhibited, necropsy lesions, and histopathological findings suggested a diagnosis of CSF. Diagnosis was confirmed by detection of CSF viral nucleic acid by reverse transcription-polyme

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Crawshaw, Helena, Kanaka S. Rachakonda, Leah Kim, Alar Enno, and Thulasi Jegatheesan. "Intensive care management of a rare case of pyrexia of unknown origin (Kikuchi-Fujimoto disease)." Anaesthesia and Intensive Care 48, no. 4 (2020): 318–23. http://dx.doi.org/10.1177/0310057x20937314.

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Kikuchi-Fujimoto disease is a rare, benign cause of necrotising lymphadenitis often presenting with fever. We describe a case of a 17-year-old boy with non-verbal autism presenting to our intensive care unit with prolonged fever of unknown cause. This case highlights the role of the intensive care unit in cases of diagnostic dilemma. The critical care community should be aware of Kikuchi-Fujimoto disease as although it is usually benign, it can rarely lead to acute airway compromise.

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Nye, George, Francois-Xavier Liebel, and Tom Harcourt-Brown. "C-reactive protein in dogs with suspected bacterial diskospondylitis: 16 cases (2010–2019)." Veterinary Record Open 7, no. 1 (2020): e000386. http://dx.doi.org/10.1136/vetreco-2019-000386.

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ObjectivesC-reactive protein (CRP) is an acute phase protein used in multiple canine inflammatory conditions including steroid responsive meningitis-arteritis, immune-mediated polyarthritis and bronchopneumonia. The aim of this study was to assess whether serum CRP is elevated in cases of diskospondylitis.MethodsMedical records from 2010 to 2019 were searched to identify dogs diagnosed with diskospondylitis based on findings consistent on CT or MRI and with CRP tested.ResultsA total of 16 dogs met the inclusion criteria. All cases had back pain. Fourteen cases had elevated CRP, with a median v

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Lim, KS, MBY Tang, and PPL Ng. "Impetigo Herpetiformis – A Rare Dermatosis of Pregnancy Associated with Prenatal Complications." Annals of the Academy of Medicine, Singapore 34, no. 9 (2005): 565–68. http://dx.doi.org/10.47102/annals-acadmedsg.v34n9p565.

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Introduction: We describe a patient who developed an acute generalised pustular eruption associated with pyrexia at 33 weeks of gestation. Clinical Picture: Her condition was complicated by preterm labour, requiring an emergency caesarean section delivery. A diagnosis of impetigo herpetiformis was made on clinicopathological grounds. Treatment: Initial treatment with topical and systemic corticosteroids failed and oral methotrexate was added. Outcome: She responded well to this therapy and required only 2 doses of weekly methotrexate. Conclusion: Impetigo herpetiformis is a rare dermatosis of

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Yong, Joanna HP, Bob K. Fonseca, Emma J. Best, Tamsin Holland, and Maria E. Craig. "Preventable illness? Purulent pericarditis due to Streptococcus pneumoniae complicated by haemolytic uraemic syndrome in an infant." Communicable Diseases Intelligence 29 (March 1, 2005): 77–79. https://doi.org/10.33321/cdi.2005.29.5.

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A previously healthy eight-month-old infant presented with shortness of breath and pyrexia. He was found to have purulent pericarditis due to Streptococcus pneumoniae, complicated by acute renal failure due to haemolytic uraemic syndrome. He received peritoneal dialysis and recovered with normalisation of renal function. This case highlights two important complications of pneumococcal infection in one individual and illustrates the need for rapid diagnosis and treatment of invasive pneumococcal disease. It is anticipated that introduction of the conjugate pneumococcal vaccination to the Austra

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