Relevant bibliographies by topics / Acyl thiourea compounds

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Academic literature on the topic 'Acyl thiourea compounds'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Acyl thiourea compounds"

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Ölmez, Nevin Arıkan, and Faryal Waseer. "New Potential Biologically Active Compounds: Synthesis and Characterization of Urea and Thiourea Derivativpes Bearing 1,2,4-oxadiazole Ring." Current Organic Synthesis 17, no. 7 (2020): 525–34. http://dx.doi.org/10.2174/1570179417666200417112106.

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Background: Urea, thiourea, and 1,2,4-oxadiazole compounds are of great interest due to their different activities such as anti-inflammatory, antiviral, analgesic, fungicidal, herbicidal, diuretic, antihelminthic and antitumor along with antimicrobial activities. Objective: In this work, we provide a new series of potential biologically active compounds containing both 1,2,4-oxadiazole and urea/thiouprea moiety. Materials and Methods: Firstly, 5-chloromethyl-3-aryl-1,2,4-oxadiazoles (3a-j) were synthesized from the reaction of different substituted amidoximes (2a-j) and chloroacetyl chloride i
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Wang, Han, Zhi-Wen Zhai, Yan-Xia Shi, et al. "Novel Trifluoromethylpyrazole Acyl Thiourea Derivatives: Synthesis, Antifungal Activity and Docking Study." Letters in Drug Design & Discovery 16, no. 7 (2019): 785–91. http://dx.doi.org/10.2174/1570180815666180704103047.

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Background: In recent years, pyrazole carboxamide derivatives possessed excellent fungicidal activity. In the process of designing new fungicides, the carboxamide group was modified in order to find novel structure pyrazole carboxamide derivatives. Methods: Ten novel trifluoromethyl pyrazole acyl thiourea derivatives were designed and synthesized. In vivo fungicidal activities of these compounds were tested against Fusarium oxysporum, Corynespora mazei and Botrytis cinerea, respectively Results: Particularly compounds exhibited significant control effective at 100 mg/L. More importantly, some
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Ru, Chengjie, Yulu Wang, Jianping Li, et al. "Synthesis and Physiological Activity of the Acyl Thiourea Compounds." Chinese Journal of Applied Chemistry 11, no. 3 (1994): 92–95. http://dx.doi.org/10.3724/j.issn.1000-0518.1994.3.92.

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Ru, Chengjie, Yulu Wang, Jianping Li, et al. "Synthesis and Physiological Activity of the Acyl Thiourea Compounds." Chinese Journal of Applied Chemistry 11, no. 3 (1994): 92–95. http://dx.doi.org/10.3724/j.issn.1000-0518.1994.3.9295.

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BREL, A. K., S. V. LISINA, K. M. ETERSKOVA, and J. N. BUDAEVA. "SYNTHESIS OF N-ACYLATED UREA AND THIOUREA BASED ON HYDROXY AND METHOXYBENZOIC ACIDS AS POTENTIAL DRUGS." IZVESTIA VOLGOGRAD STATE TECHNICAL UNIVERSITY, no. 12(295) (December 2024): 21–27. https://doi.org/10.35211/1990-5297-2024-12-295-21-27.

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N-acylated ureas and thioureas based on hydroxy- and methoxybenzoic acids were synthesized using the Schotten-Baumann reaction in two stages without isolating the intermediate acyl chloride (one-pot multicomponent synthesis) under optimal conditions. The structure of the obtained compounds was confirmed by 1H and 13C NMR spectroscopy. The spectrum of biological activity of the compounds was estimated using the PASS (Predictor of Activity Spectra for Substance) program. Using the ChemAxon online platform, theoretical calculations of descriptor values such as hydrophilic-lipophilic balance (LogP
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6

Al-Amily, Duraid H., and Mohammed Hassan Mohammed. "Design, Synthesis, and Docking Study of Acyl Thiourea Derivatives as Possible Histone Deacetylase Inhibitors with a Novel Zinc Binding Group." Scientia Pharmaceutica 87, no. 4 (2019): 28. http://dx.doi.org/10.3390/scipharm87040028.

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Histone deacetylase inhibitors with zinc binding groups often exhibit drawbacks like non-selectivity or toxic effects. Thus, there are continuous efforts to modify the currently available inhibitors or to discover new derivatives to overcome these problems. One approach is to synthesize new compounds with novel zinc binding groups. The present study describes the utilization of acyl thiourea functionality, known to possess the ability to complex with metals, to be a novel zinc binding group incorporated into the designed histone deacetylase inhibitors. N-adipoyl monoanilide thiourea (4) and N-
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7

Sijia, Xue, Guo Yanling, Li Jingzhi, Ke Shaoyong, and Duan Liping. "Synthesis and biological activity of N'-(substituted pyrimidin-2-yl)- N-dichlorochrysanthemoyl thioureas and their fused heterocyclic compounds." Journal of Indian Chemical Society Vol. 82, Mar 2005 (2005): 262–64. https://doi.org/10.5281/zenodo.5827025.

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College of Life-and Environmental Science, Department of Chemistry, Shanghai Normal University, Shanghai, 200234, P. R. China <em>E-mail</em> : ylguo420@ 163.com <em>Manuscript received 25 June 2004, accepted 24 November 2004</em> Five <em>N&#39;</em> -(substituted pyrimidin-2-yi)-<em>N</em>-dichlorochrysanthemoyl thioureas (Sa-Se) were synthesized from corresponding dichlorochrysanthemic acid in three steps. And two dichlorochrysanthemoylimino-2<em>H</em>-1,2,4-thiadiazolo[2,3-a]pyrimidines were prepared by oxidizing cyclization of 5a, 5b. The structures of these novel target compounds were c
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8

Nossa González, Diana L., Aamer Saeed, Ghulam Shabir, Ulrich Flörke, and Mauricio F. Erben. "Conformational and crystal structure of acyl thiourea compounds: The case of the simple (2,2-dimethyl-propionyl) thiourea derivative." Journal of Molecular Structure 1215 (September 2020): 128227. http://dx.doi.org/10.1016/j.molstruc.2020.128227.

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9

Makhaeva, Galina F., Nadezhda V. Kovaleva, Natalia P. Boltneva, et al. "Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer’s Activity Profile." Molecules 27, no. 3 (2022): 1060. http://dx.doi.org/10.3390/molecules27031060.

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Using two ways of functionalizing amiridine—acylation with chloroacetic acid chloride and reaction with thiophosgene—we have synthesized new homobivalent bis-amiridines joined by two different spacers—bis-N-acyl-alkylene (3) and bis-N-thiourea-alkylene (5) —as potential multifunctional agents for the treatment of Alzheimer’s disease (AD). All compounds exhibited high inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with selectivity for BChE. These new agents displayed negligible carboxylesterase inhibition, suggesting a probable lack of untoward drug–dru
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10

J. Ekowati, D. Pebrianti, G. C. Ananda, D. R. Ramadhan, R. Widyowati, and K. A. Nofianti. "DESIGN AND SYNTHESIS NOVEL COMPOUNDS OF ORTHOCOUMARIC ACID DERIVATES AS ANTI-THROMBOTIC CANDIDATE." RASAYAN Journal of Chemistry 17, no. 03 (2024): 1387–94. http://dx.doi.org/10.31788/rjc.2024.1738657.

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It has been reported that aspirin and P2Y inhibitors have emerged as the preferred therapeutic agents for managing vaso-occlusive illness due to their anti-thrombotic properties. However, complaints about the side effects of these drugs are still being reported. Ongoing research is being conducted on the design and development of novel antithrombotic agents to obtain good health and well-being. ortho-Coumaric acid derivates were designed using the ChemDraw program, while a physicochemical prediction study was carried out by the Swiss ADME program, and the MOE platform was operated to predict t
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Dissertations / Theses on the topic "Acyl thiourea compounds"

1

Klopper, Reynhardt. "An investigation into the complex formation and potential solvent extraction of Os(IV/III) with N, N - dialkyl - N′- acyl(aroyl)thioureas." Thesis, Stellenbosch : University of Stellenbosch, 2006. http://hdl.handle.net/10019.1/2762.

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Thesis (MSc (Chemistry and Polymer Science))--University of Stellenbosch, 2006.<br>This study involved the preliminary investigation into the potential liquid-liquid extraction of Os(IV/III) from hydrochloric acid solutions with ligands of type N,N-dialkyl-N′-acyl(aroyl)thioureas (HL), and ultimate selective pre-concentration and separation of Os(IV/III) from the other platinum group metals. Investigations have also been focused towards understanding the speciation of Os(IV) in hydrochloric acid medium. A series of osmium complexes with ligands of type HL have been synthesised and characteris
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