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Dissertations / Theses on the topic 'ADAMTS 1 e 4'

Author: Grafiati

Published: 4 June 2021

Last updated: 2 February 2022

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1

Hsu, Yi-Ping. "The role of ADAMTS-4 and ADAMTS-1 in angiogenesis." Thesis, University of Sheffield, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.577642.

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Endothelial cells (ECs) form the innermost layer of all blood vessels, and their function and behaviour are important in angiogenesis. VEGF is the most potent angiogenic factor stimulating EC proliferation, migration, and differentiation as well as survival. Vascular endothelial growth factor receptor 2 (VEGFR2) is the major VEGF receptor which mediates VEGF-induced angiogenesis on ECs. Neuropilin 1 (NRPI) is a VEGF co-receptor that enhances VEGF-stimulated VEGFR2 angiogenic signals. A disintegrin and metalloproteinase with thrombospondin repeats (ADAMTS)-I, -2, -5, -8, and -9 have been shown

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2

Turner, Sharon Louise. "Investigation of ADAM17 and ADAMTS-1, -4 and -5 in liver carcinoma." Thesis, Sheffield Hallam University, 2009. http://shura.shu.ac.uk/20827/.

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Background: Proteolytic enzymes are important mediators of cellular proliferation, angiogenesis and remodelling of the extracellular matrix (ECM); all processes required for tumour growth and metastasis. However, the studies of proteolytic enzymes in hepatic tumours, both primary and metastatic, have largely been limited to specific matrix metalloproteinases e.g. MMP-2, -7 and -9, and urokinase-type plasminogen activator. ADAM17 (a disintegrin and metalloproteinase 17), a membrane-bound sheddase, releases membrane-bound proteins including growth factors, which could contribute to liver tumour

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3

Gibrel, Gehan G. F. "The role of ADAMTS-1, -4 and -5 in multiple sclerosis." Thesis, Sheffield Hallam University, 2012. http://shura.shu.ac.uk/20683/.

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ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-1, -4 and -5 are secreted enzymes which are members of the glutamyl endopeptidases (GEPs) group of ADAMTSs. These enzymes break down chondroitin sulphate proteoglycans (CSPGs) which are key components of brain extracellular matrix (ECM). In multiple sclerosis (MS), CSPG breakdown by ADAMTSs may enable axonal regeneration or conversely it may lead to alterations of the ECM, allowing influx of inflammatory cells promoting tissue damage. ADAMTS-1, -4 and -5 mRNA expression was studied by quantitative real-time PCR (qRT-PCR) u

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4

Owen, Kathryn. "Characterisation of ADAMTS-4 endocytosis by chondrosarcoma cells and chondrocytes." Thesis, Imperial College London, 2009. http://hdl.handle.net/10044/1/5575.

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Aggrecan is one of the most abundant components of the articular cartilage matrix and its degradation by aggrecanases is considered to be a key early event in the development of osteoarthritis. This study investigates whether the extracellular level of ADAMTS-4 (a disintegrin and metalloproteinase with thrombospondin type 1 motifs-4), one of the most studied aggrecanases, can be regulated by receptor-mediated endocytosis. Exogenously-added ADAMTS-4 disappeared from the medium of HTB94 cells and TCA-soluble degradation products of ADAMTS-4 increased in the medium over time. Fluorescent-labeled

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5

Lim, Ngee Han. "TIMP-3 interaction with aggrecanase 1 (ADAMTS-4) and aggrecanse 2 (ADAMTS-5)investigated by site-directed mutagenesis." Thesis, Imperial College London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506803.

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Degradation of the proteoglycan aggrecan, one ofthe major components ofthe cartilage matrix, is thought to be a critical step in the development of osteoarthritis (OA). Both matrix metalloproteinases (MMPs) and aggrecanases [members of the ADAMTS (a disintegrin and metalloprotease with thrombospondin motifs) family have been shown to degrade aggrecan in vitro. However, there is debate as to their relative roles in vivo. The tissue inhibitor of metalloproteinases 3 (TIMP-3), which inhibits the MMPs, is the most potent tissue inhibitor of the aggrecanases, ADAMTS-4 and ADAMTS-S. The purpose of t

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6

Xie, Zhe. "Wnt signaling in human cartilage degeneration and chondrocytes de-differentiation." Thesis, Université de Lorraine, 2016. http://www.theses.fr/2016LORR0111/document.

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La dérégulation de la signalisation Wnt est impliquée dans les anomalies du développement et dans la pathogenèse de nombreuses maladies, y compris l'arthrose. Au cours de ce travail, nous avons étudié l'effet de Wnt-3a sur l’ADAMTS-4 dans les explants de cartilage et les chondrocytes primaires humains. Nous avons observé que Wnt-3a régule négativement l'expression de cette agrecanase et avons démontré que cette inhibition est médiée par Frizzled-8 via l’activation de la voie canonique et inhibition de l'activité de NFκB. En outre, nous avons montré que Wnt-3a est capable de s’opposer à l'induc

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7

Lima, Maíra de Assis. "Influência dos hormônios esteroidais na migração, invasão e expressão das proteases ADAMTS 1 e 4 em células derivadas de tumores de ovários." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/42/42134/tde-05102015-190307/.

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O câncer de ovário é uma neoplasia ginecológica e alternâncias hormonais poderiam ter um papel na manifestação da doença. As ADAMTS´s são proteases secretadas dependentes de Zn2+/Ca2+. Nosso objetivo foi avaliar se há Influência de hormônios sexuais nos níveis de expressão de mRNA, proteínas e distribuição de ADAMTS 1 e 4 e alteração na migração e invasão em células tumorais humanas de ovário. As linhagens foram tratadas com progesterona, estrógeno ou testosterona e o controle não recebeu tratamento. O estrógeno e a testosterona induziram uma menor e a progesterona uma maior expressão gênica d

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8

Gendron, Christi Marie. "Investigation of the role of ADAMTS-4 and ADAMTS-5 in cartilage aggrecan degradation." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415906.

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9

Jones, Gavin Carl. "Molecular interactions and activities of ADAMTS-4 and -5." Thesis, University of Sheffield, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412783.

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10

Le, Behot Audrey. "Nouvelles cibles thérapeutiques de l'accident vasculaire cérébral : GpIbα et ADAMTS-4". Caen, 2013. http://www.theses.fr/2013CAEN3164.

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Le seul traitement aigu de l’AVC ischémique est la thrombolyse par l’activateur tissulaire du plasminogène recombinant (rtPA). Néanmoins, l’efficacité de la thrombolyse est influencée par la composition du thrombus : lorsqu’il est riche en plaquettes, il est résistant au rtPA. En modélisant in vivo 2 étiologies (embolique et thrombose in situ) de l’AVC ischémique, l’objectif de ce travail a été d’étudier l’efficacité de la thrombolyse et les mécanismes de la thrombose. Dans les conditions ischémiques, la limitation des dommages cérébraux dépend du rétablissement rapide de la perfusion sanguine

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11

Molokwu, Chidiebele N. "The functional role of ADAMTS-1 and -15 in prostate cancer progression." Thesis, University of Sheffield, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.577535.

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Introduction: Prostate cancer is a leading cause of cancer death in men. Death is usually a consequence of castration resistant tumour progression. Some metalloproteinases are implicated in the process of cancer progression. ADAMTS proteinases (A Disintegrin And Metalloproteinase with ThromboSpondin motifs) are metalloproteinases that play diverse roles in tissues. Prostate cancer cells express ADAMTS-l and -15 but the role played by these proteinases in prostate cancer progression is unknown. This study was designed to determine the role of ADAMTS-l and 15 in prostate cancer progression. Mate

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12

Santamaria, Salvatore. "Screening, isolation and characterisation of antibodies that block aggrecanase activity of ADAMTS-5." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/22156.

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A Disintegrin and Metalloproteinase with ThromboSpondin Motif (ADAMTS)-5 is considered to play a key role in degradation of aggrecan during the progression of osteoarthritis (OA). Thus, ADAMTS-5 inhibitors are emerging as potential disease-modifying OA drugs. The generation of small molecule inhibitors of metalloproteinases has not achieved successful outcomes primarily due to the lack of selectivity. On the other hand, monoclonal antibodies were proved potent and selective binders of many biologically relevant targets. We therefore aimed to isolate inhibitory antibodies against ADAMTS-5. A hu

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13

SOUZA, NETO Osvaldo Rodrigues de. "Análise imunohistoquímica da ADAMTS-1 e proteoglicanos no ameloblastoma e no tumor odontogênico cístico calcificante." Universidade Federal do Pará, 2014. http://repositorio.ufpa.br/jspui/handle/2011/5836.

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Submitted by Cleide Dantas (cleidedantas@ufpa.br) on 2014-10-01T13:02:23Z No. of bitstreams: 2 license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) Dissertacao_AnaliseImunohistoquímicaAdamts.pdf: 2182822 bytes, checksum: f614e4856b0e4ff30df45d31a8939a93 (MD5)<br>Approved for entry into archive by Ana Rosa Silva (arosa@ufpa.br) on 2014-10-07T13:13:41Z (GMT) No. of bitstreams: 2 license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) Dissertacao_AnaliseImunohistoquímicaAdamts.pdf: 2182822 bytes, checksum: f614e4856b0e4ff30df45d31a8939a93 (MD5)<br>Mad

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14

Marketing, Universidad Peruana de Ciencias Aplicadas Facultad de Administración y. "Retail 4 Parte 1[1]." Universidad Peruana de Ciencias Aplicadas - UPC, 2008. http://hdl.handle.net/10757/272539.

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15

Silva, Suély Vieira da. "Influência do estrógeno, progesterona e testosterona nos níveis de expressão e na distribuição de ADAMTS-1 (uma desintegrina e metaloproteinase com domínios trombospondinas 1) em células mamárias humanas normais e tumorais." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/42/42134/tde-19022015-164340/.

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O câncer de mama é no Brasil o segundo maior causador de morte entre mulheres. Os hormônios sexuais estão dentre os vários fatores indutores ou promotores da carcinogênese. ADAMTS (uma desintegrina e metaloproteinase com domínios trombospondina) é uma enzima Zn2+/Ca2+dependente. Avaliamos a influência dos hormônios na expressão e localização da ADAMTS-1 em 3 linhagens de mama. qPCR demonstrou que a progesterona estimulou o aumento de mRNA de ADAMTS-1 na MCF-10A e na MDA-MB-231, o tratamento com estrógeno e progesterona estimulou a diminuição. No Western blot observamos nas linhagens MCF-10A e

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16

Lemarchant, Sighild. "L' axe activateur tissulaire du plasminogène (tPA) – désintégrine et métalloprotéinase à motifs thrombospondines de type 4 (ADAMTS-4) : une nouvelle cible thérapeutique des traumatismes de la moelle épinière." Caen, 2011. http://www.theses.fr/2011CAEN3134.

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La prise en charge et le traitement des traumatismes médullaires (TM) sont des enjeux médicaux et économiques importants, sources de nombreuses études cliniques et expérimentales. La cicatrice gliale participe à la mise en place d’un environnement délétère pour la régénération axonale, de par la synthèse et la libération de protéoglycanes de type chondroïtine sulfate (CSPGs), notamment par les astrocytes réactifs. L’activateur tissulaire du plasminogène (tPA) est une sérine protéase exerçant de nombreux dans le système nerveux central (SNC). L’objectif de nos travaux était de déterminer l’infl

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17

Tembo, Norbert Olivier. "Synthèse et étude physicochimique des 4-amino-1, 2, 3, 4-tétrahydro-1-isoquinolones et 2-quinolones ; 4-aryl-2, 3-dihydropyrrolizines ; 4-aryl-1-oxo-1, 2, 3, 4-tétrahydro-pyrrolo [1, 2-a] pyrazines ; 4-aryl-2-imidazolidinones." Caen, 1990. http://www.theses.fr/1990CAEN4044.

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18

Longpré, Jean-Michel. "Identification de déterminants moléculaires impliqués dans la biosynthèse et l'activation des ADAMTS (a desintegrin and metalloprotease with thrombospondin type 1 repeat)." Thèse, Université de Sherbrooke, 2007. http://savoirs.usherbrooke.ca/handle/11143/4260.

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Les ADAMTS (a desintegrin and metalloprotease with thrombospondin type 1 repeat) sont des métallopeptidases sécrétées dans le milieu extracellulaire ayant comme fonction le clivage de différents substrats de la matrice extracellulaire tel le propeptide en N-terminal du collagène, l'aggrécan, ainsi que le von Willebrand factor retrouvé dans le plasma. Une mutation ou un dérèglement d'ADAMTS2, 5 et 13 sont directement responsable du syndrome de Ehlers-Danlos de type VII C, l'arthrose et la purpura thrombotique thrombocytopénique respectivement. De plus, ADAMTS1 et 8 sont reconnues pour avoir des

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19

Mayeur, Anne. "Role de la protéine ADAMTS 4 sur la repousse nerveuse centrale induite par les cellules gliales olfactives in vivo chez la souris. Potential of olfactory ensheathing cells from different sources for spinal cord repair Inhibition of ADAMTS-4 Expression in Olfactory Ensheathing Cells Enhances Recovery after Transplantation within Spinal Cord Injury." Thesis, Normandie, 2020. http://www.theses.fr/2020NORMR003.

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Une lésion de la moelle épinière induit une perte sensorimotrice permanente en sous-lésionnel. A ce jour, une grande variété de cellules a été utilisée comme biothérapie pour soigner les lésions médullaires dans différents modèles animaux. Les cellules gliales olfactives (CGO) sont l’une des plus prometteuses. En effet, il a été démontré que les CGO améliorent la récupération dans de nombreuses études sur les animaux, ainsi que sur des patients (essais de Phase I/Iia). Cependant, il a été rapporté que le niveau de récupération varie significativement selon les patients. Par conséquent, il est

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20

Araya, Naranjo Sandra. "Población de una base de datos jurisprudencial a base de libros de registro de sentencias de protección de la corte suprema, mayo 3-3, año 2004, julio 1-4, 2-4, 3-4, 4-4, año 2004, diciembre 1-4, 2-4, 3-4, 4-4, año 2004; enero 1-4, 2-4, 3-4, 4-4 año 2005, febrero 1-2, 2-2, año 2005." Tesis, Universidad de Chile, 2005. http://www.repositorio.uchile.cl/handle/2250/113738.

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Memoria (licenciado en ciencias jurídicas y sociales)<br>No autorizada por el autor para ser publicada a texto completo<br>En la realización de la Tesis analice 356 fallos emanados de la Ilustrísima Corte Suprema de Justicia, de ellos se extractaron definitivamente 322 fallos, en su mayoría son Recursos de Protección, aunque también fueron analizados en menor número Recursos de Amparo Económico.

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21

Lindberg, Erik. "1:2:3:4." Thesis, KTH, Arkitektur, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-169058.

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Mitt examensprojekt är en experimentell undersökning av proportionalitet som vägledande princip i den arkitektoniska formgivningprocessen. Proportionslära ansågs länge vara en viktig del av arkitekturämnet, men är idag mest något som hör arkitekturhistorien till. Det ursprungligen matematiska begreppet proportionalitet har utvidgats men i och med det också urvattnats. Euklides definierar det så här: en första storhet förhåller sig till en andra storhet så som den andra storheten förhåller sig till en tredje. En gång i tiden ansågs en byggnads skönhet och dess proportionerliga förhållande delar

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22

Pinheiro, Paulo Rogerio Dias. "Modelo 3-4-1 reduzido." Universidade Federal da Paraíba, 2013. http://tede.biblioteca.ufpb.br:8080/handle/tede/5735.

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Made available in DSpace on 2015-05-14T12:14:08Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 787601 bytes, checksum: dde905a364661fdc51ee261d059b2905 (MD5) Previous issue date: 2013-08-23<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>We build a gauge model based on the SU(3)C ⊗ SU(4)L ⊗ U(1)X symmetry where the scalar spectrum needed to generate gauge boson and fermion masses is reduced to a lesser content than usually assumed in literature. In order to guarantee that such a reduction is self-consistent, we first show that the model possesses a Landau pole at

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23

Ebert, Daniel John. "Chiasm and christology in Hebrews 1:1-4." Theological Research Exchange Network (TREN), 1986. http://www.tren.com.

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24

Lépine, Matthieu. "Modulation enzymatique des réseaux périneuronaux par la désintégrine et métalloprotéinase à motifs thrombospondines de type 4 (ADAMTS-4) et l'activateur tissulaire du plasminogène (tPA) tPA originating from parvalbumin interneurons controls the remodeling of perineuronal nets." Thesis, Normandie, 2020. http://www.theses.fr/2020NORMC425.

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Les réseaux périneuronaux (perineuronal nets, PNNs) sont des structures de la matrice extracellulaire, qui enveloppent préférentiellement les interneurones exprimant la parvalbumine (PV). Ils régulent l’activité neuronale, protègent contre le stress oxydatif et ferment les périodes critiques du développement. La dégradation des PNNs restaure la plasticité cérébrale et améliore la récupération fonctionnelle dans différentes pathologies cérébrales. Une meilleure compréhension des mécanismes enzymatiques modulant les PNNs peuvent conduire au développement de nouveaux outils thérapeutiques. Nos tr

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25

梁曼儀 and Man-yee Leung. "Synthetic investigations into [delta]4-1, 2-thiazoline 1, 1-dioxides." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1985. http://hub.hku.hk/bib/B31207340.

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Leung, Man-yee. "Synthetic investigations into [delta]4-1, 2-thiazoline 1, 1-dioxides /." [Hong Kong : University of Hong Kong], 1985. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12348739.

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27

Davis, James. "Sarkinos vs. sarkikos in 1 Cor. 3:1-4." Theological Research Exchange Network (TREN), 1993. http://www.tren.com.

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Thesis (Th. M.)--Washington Bible College, 1993.<br>"Sarkinos" and "sarkikos" appear in Greek letters on t.p. "A thesis presented to the faculty of the Capital Bible Seminary in partial fulfillment of the requirements for the degree Master of Theology." Includes bibliographical references (leaves 59-64).

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28

Luheshi, Abdul-Basset Nuri. "Cycloadditions to 1-azetines and 1-azetin-4-ones." Thesis, University of Salford, 1988. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327973.

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29

Kronosjö, Anton. "Hurwitz 1, 2, 4, 8-sats." Thesis, Uppsala universitet, Algebra och geometri, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-201509.

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30

Dossett, David Lawrence. "Alternatives to [4+1] carbocyclic annulations." Thesis, Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/101269.

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6-Carboethoxybicyclo [3.3.0] oct-6-en-2-one has been prepared by the intramolecular [4+1] cyclopentene annulation method. This compound and its precursor, 6-vinyl-6-carboethoxybicyclo[3.1.0]hexan-2-one were attained as the necessary standards for the investigation of the course of intramolecular Michael addition-alkylation sequence of l-phenylsulfonyl-6-carboethoxyocta-5,7-dien-2-one.<br>M.S.

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Johansson, Melin Emma. "Hurwitz 1-, 2-, 4-, 8-sats." Thesis, Uppsala universitet, Algebra och geometri, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-453228.

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Said, Cina. "Die Herstellung zweier mRNA-Sonden für Chondroitin-4-Sulfotransferase 1 und Dermatan-4-Sulfotransferase 1 des Zebrafisches /." Hamburg, 2008. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000278377.

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Dardemann, Jörg. "Synthese und enzymatische Umsetzung modifizierter Donorsubstrate mit dem Enzym ss(1-]4)Galactosyltransferase [Beta(1-]4)Galactosyltransferase]." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968788475.

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Bélair, Caroline. "A-ß¦1¦-¦4¦2 and A-ß¦1¦-¦4¦0 induce tau phosphorylation in human neurons." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0007/MQ29653.pdf.

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Herman, John D. "Paul's rhetoric of the cross in 1 Corinthians 1-4." Theological Research Exchange Network (TREN), 1993. http://www.tren.com.

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Fasolini, Andrea. "Supporting Cubane’s Renaissance: Metathesis reactions on 4-iodo-1-vinylcubane and Stetter reaction on 1-iodocubane-4-carboxaldehyde." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amslaurea.unibo.it/11952/.

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Cubane is a peculiar cube-shaped alkane molecule with a rigid, regular structure. This makes it a good scaffold, i.e. a molecular platform to which the substituents are arranged in a specific and fixed orientation. Moreover, cubane has a body diagonal of 2.72 Å, very similar to the distance across the benzene ring, i.e. 2.79 Å. Thus, it would be possible to use cubane as a scaffold in medicinal and material chemistry as a benzene isostere 1,2. This could lead to advantages in terms of solubility and toxicity and could provide novel properties. For this purpose, the possibility of performing “m

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CHARRIER, JEAN-DAMIEN. "1-oxa-4-azabutadienes et 1-thia-4-azabutadienes precurseurs d'heterocycles soufres et azotes et de ligands tetradentes." Nantes, 1996. http://www.theses.fr/1996NANT2088.

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Le travail rapporte est consacre a l'etude d'enchainements 1-oxa-4-azabutadienes et 1-thia-4-azabutadienes ainsi qu'a leur utilisation en synthese heterocyclique. Dans le premier chapitre, la preparation de 2-hydrazonothioacetophenones stables est decrite. Ces composes permettent d'acceder, par des reactions de cycloaddition 4+2, aux 1,4-thiazines dans de bonnes conditions. Le second chapitre est consacre a la reaction de sulfuration de benzile monohydrazones, qui conduit aux 3,6-dihydro-2h-1,3,4-thiadiazines, heterocycles possedant de nombreuses applications dans le domaine pharmacologique. L

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Winquist, Matthew L. "Sharing in Christ's sufferings (1 Peter 4)." Theological Research Exchange Network (TREN) Access this title online, 2005. http://www.tren.com.

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Center, University of Arizona Water Resources Research. "Arroyo Vol. 4 No. 1 (April 1990)." Water Resources Research Center, College of Agriculture, University of Arizona (Tucson, AZ), 1990. http://hdl.handle.net/10150/314790.

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Although many and varied, all sources of water pollution are classified as either point or nonpoint. Pollution comes from a point source if its origins are distinct and identifiable; hence, point source is also called an end-of-the-pipe source. Pollution from point sources can usually be quantified, often by direct measurement. Point sources can often be regulated effectively with federal and state permits.

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Herrera, Burstein Valia María. "Psicología General (RRHH), Presentación 4 (2007-1)." Universidad Peruana de Ciencias Aplicadas - UPC, 2007. http://hdl.handle.net/10757/272408.

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Webster, Charles. "Lordship and faith in Romans 1-4." Online full text .pdf document, available to Fuller patrons only, 2002. http://www.tren.com.

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Elggren, Sara. "No. 1-2-3-4! : (Motoric Key)." Thesis, Konstfack, Textil, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:konstfack:diva-5609.

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No. 1-2-3-4! (Motoric Key) consist of a weave series and a printed edition. Each piece with the outline 21x21 cm, a size similar to a hand, or a handkerchief, generic in the relation to a blueprint of a weave sample or a leaflet; a utilitarian object to use and be used. An economical outline that enables a mobility and simplicity of direction. A one made as one, one, one, through two years. A handkerchief tool. Potential efficiency, tunes and characters, stating the importance of listening as a way of working.

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43

BEN, HAMIDA NAJIB. "Chimie heterocyclique du geranium et du silicium : heterocycles a enchainement m#1#4-x (m#1#4=si ou ge, x=o, s) et polymetalles a liaison m#1#4-m (m#1#4=si ou ge, m=hg), fe, ru, co)." Toulouse 3, 1989. http://www.theses.fr/1989TOU30099.

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Synthese des heterocycles: me#2gech#2ge(me#2)s (et son dimere) et me#2gehgge(me#2)ch#2ge(me#2)hgge(me#2)ch#2, des clusters me#2sich#2ge(me#2)fe(co)#4fe(co#4), me#2ge(ch#2)#nge(me#2)co#2(co)#7, me#2ge(ch#2)#nge(me#2)m+(co)#4 (n=1, 2; m=fe, ru). Etude de leur structure, de leur reactivite et de leur decomposition chimique

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44

Woodard-Grice, Alencia V. "Hyposialylation regulates [alpha]4[beta]1 integrin binding to VCAM-1." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2009r/woodard.pdf.

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Olusegun-Osoba, Elizabeth Oluwakemi. "Strategies towards the synthesis of 4-(3-methyl-but-1-enyl)-3,5,3',4'-tetrahydroxystilbene (arachidin-1) and resveratrol analogues." Thesis, University of Hertfordshire, 2015. http://hdl.handle.net/2299/17118.

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Stilbene phytoalexins such as resveratrol, 1, and the arachidins, including arachidin-1,2, are naturally synthesised by peanut (Arachis hypogaea) plants. The peanut phytoalexins are polyphenolic compounds consisting of a stilbene backbone, with a number of derivatives also possessing a prenyl moiety. These distinctive phytoalexins have gained attention, as they exhibit various biological activities, for instance arachidin-1, 2, has been reported to be more potent than resveratrol, 1, in the inhibition of lipopolysaccharide-induced expression of cyclooxygenase-2 (COX-2) and COX-2 mRNA, in vitro

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46

Amaral, Carlos Henrique Oliveira do. "Síntese e cristaloquímica do 1-(4-carboxifenil)-3-(4-acetilamidofenil)triazeno e complexos de cobre(i), prata(I) e ouro(I) com o ligante 1-(4-nitrofenil)-3-(4-etoxicarboxifenil)triazenido." Universidade Federal de Santa Maria, 2007. http://repositorio.ufsm.br/handle/1/10414.

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This work deals with the determination of the single crystal structure analysis of four triazenido complexes including gold(I), copper(I), silver(I), and the crystal structure of a free triazene molecule. Crystal data and refinement indices of 1-(4-carboxyphenyl)-3-(4- acetylamidophenyl)triazene (1) are: monoclinic system, space group P21/n, cell parameters a = 7.772(1), b = 9.7365(2), c = 19.55(3) Å, β = 93.435(1)º, Z = 4, R1 = 0.0394, wR2 = 0.0632. The crystal structure show that the molecule deviates significantly from planarity (r.m.s. 0.342 Å). The molecules of (1) are associated to a bi-

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Sargin, Saniye Pinar. "Model Studies on the Phase Behavior of 4-cyano-4'-n-pentyloxybiphenyl." Phd thesis, [S.l. : s.n.], 2000. http://tuprints.ulb.tu-darmstadt.de/32/1/PTez1son.pdf.

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The term liquid crystal signifies a state of aggregation that is intermediate between the crystalline solid and the amorphous liquid. A substance in this state is strongly anisotropic in some of its properties and yet shows a certain degree of fluidity, which in some cases is comparable to that of an ordinary liquid. Compounds like 4-cyano-4'-n-alkyloxybiphenyl (nOCB), 4-cyano-4'-n-alkylbiphenyl (nCB), where n stands for the number of carbon atoms in the alkoxy (or in the alkyl) group, are known to be rod-shaped molecules, which have an elongated, anisotropic geometry allowing for prefential a

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48

Nydegger, Brett. "Anesthetic efficacy of 4% articaine with 1:100,000 epinephrine, 4% prilocaine with 1:200,000 epinephrine, and 4% lidocaine with 1:100,000 epinephrine as a primary buccal infiltration of the mandibular first molar." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1375785136.

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49

Guerret, Olivier. "Nouveaux ligands carbeniques : 1, 2, 4-triazolis (ylidene) and 1, 2, 4-triazoliumylidene : utilisation de ces ligands en chimie organometallique." Toulouse 3, 1997. http://www.theses.fr/1997TOU30275.

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Le premier chapitre presente l'etat de l'art en matiere de carbenes stables, ce qui permet de situer les presents travaux par rapport a la litterature. La deuxieme chapitre concerne la description theorique des carbenes cibles : 1,2,4-triazol-bis(ylidene), 1,2,4-triazolium-ylidene. Il s'agit respectivement, d'un cycle bis(carbenique) et d'un cycle cationique carbenique. L'etude a ete menee a l'aide de calculs ab initio. Leur stabilite est discutee : la delocalisation aromatique des six electrons provenant des paires libres des trois atomes d'azote presents dans chaque cycle explique principale

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50

Feddal, Salima. "Approche des lesions moleculaires responsables de l'elliptocytose hereditaire 4. 1() en haute-savoie et de la proteine 4. 1 presles." Paris 7, 1992. http://www.theses.fr/1992PA077059.

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L'elliptocytose hereditaire (eh) 4. 1() est une variete de l'elliptocytose resultant de la reduction ou l'absence de la proteine 4. 1. Nous rapportons l'etude faite sur 9 familles originaires de la haute-savoie et porteuses d'eh 4. 1(). L'etude des arbres genealogiques, en remontant jusqu'au 18eme siecle, a permis de diviser ces familles en deux groupes. L'analyse des adn des 9 familles par southern blot, en utilisant trois sondes adnc couvrant au total toute la partie codante ainsi qu'une partie des sequences 5 et 3 non traduite, ne montre pas de rearrangement genomique majeur. En revanche, s

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