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Journal articles on the topic 'Adaptive homeostasis'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Davies, Kelvin J. A. "Adaptive homeostasis." Molecular Aspects of Medicine 49 (June 2016): 1–7. http://dx.doi.org/10.1016/j.mam.2016.04.007.

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Lomeli, Naomi, Daniela A. Bota, and Kelvin J. A. Davies. "Diminished stress resistance and defective adaptive homeostasis in age-related diseases." Clinical Science 131, no. 21 (2017): 2573–99. http://dx.doi.org/10.1042/cs20160982.

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Adaptive homeostasis is defined as the transient expansion or contraction of the homeostatic range following exposure to subtoxic, non-damaging, signaling molecules or events, or the removal or cessation of such molecules or events (Mol. Aspects Med. (2016) 49, 1–7). Adaptive homeostasis allows us to transiently adapt (and then de-adapt) to fluctuating levels of internal and external stressors. The ability to cope with transient changes in internal and external environmental stress, however, diminishes with age. Declining adaptive homeostasis may make older people more susceptible to many dise

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Showkatbakhsh, Milad, and Mohammed Makki. "Application of homeostatic principles within evolutionary design processes: adaptive urban tissues." Journal of Computational Design and Engineering 7, no. 1 (2020): 1–17. http://dx.doi.org/10.1093/jcde/qwaa002.

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Abstract Nature is a repository of dynamic and intertwined processes ready to be analyzed and simulated. Homeostasis, as a scale-free and universal biological process across all species, ensures adaptability to perturbations caused by intrinsic and extrinsic stimuli. Homeostatic processes by which species maintain their stability are strongly present through ontogenetic and phylogenetic histories of living beings. Forms and behaviors of species are imperative to their homeostatic conditions. Although biomimicry has been established for many decades, and has made significant contributions to en

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Никитин, О. Ю., and O. Yu Nikitin. "Analysis of Adaptivity and Plasticity in the Network of Homeostatic Neurons." Mathematical Biology and Bioinformatics 11, no. 2 (2016): 351–66. http://dx.doi.org/10.17537/2016.11.351.

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Here we present the model of bioinspired neuron, incorporating cellular homeostasis. We propose the modified STDP plasticity rule, including influence of the input signal on the neuronal cellular homeostatic state. Properties of the network of proposed neurons have been studied. The network was used to control adaptive behavior of an agent in the multi-task environment. Statistical study was performed to find out the adaptive properties of the network with different levels of homeostatical plasticity. Model of the network, incorporating full homeostatically dependent weight correction was able

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Arslanbaeva, Liaisan R., and Massimo M. Santoro. "Adaptive redox homeostasis in cutaneous melanoma." Redox Biology 37 (October 2020): 101753. http://dx.doi.org/10.1016/j.redox.2020.101753.

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Davies, Kelvin J. A. "The redox biology of adaptive homeostasis." Free Radical Biology and Medicine 218 (June 2024): 1. http://dx.doi.org/10.1016/j.freeradbiomed.2024.04.008.

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Davies, Kelvin J. A. "The Decline of Adaptive Homeostasis & Adaptive Proteostasis in Ageing." Free Radical Biology and Medicine 120 (May 2018): S5. http://dx.doi.org/10.1016/j.freeradbiomed.2018.04.019.

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8

Sarosiek, Anna. "Homeostasis as a foundation for adaptive and emotional artificial intelligence." Philosophical Problems in Science (Zagadnienia Filozoficzne w Nauce), no. 77 (April 29, 2025): 41–54. https://doi.org/10.59203/zfn.77.706.

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Homeostasis, a fundamental biological mechanism, enables living organisms to maintain internal balance despite changing environmental conditions. Inspired by these adaptive processes, research into artificial intelligence (AI) seeks to develop systems capable of dynamic adaptation, introspection, and empathetic interactions with users. This article explores the potential of implementing homeostatic mechanisms in AI as a foundation for emotional intelligence and self-regulation. Key questions include the distinction between simulation and actual experience, the role of machine introspection, an

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Wang, Shi Qiang, Edward G. Lakatta, Heping Cheng, and Zeng Quan Zhou. "Adaptive mechanisms of intracellular calcium homeostasis in mammalian hibernators." Journal of Experimental Biology 205, no. 19 (2002): 2957–62. http://dx.doi.org/10.1242/jeb.205.19.2957.

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SUMMARYIntracellular Ca2+ homeostasis is a prerequisite for a healthy cell life. While cells from some mammals may suffer dysregulation of intracellular Ca2+ levels under certain deleterious and stressful conditions, including hypothermia and ischemia, cells from mammalian hibernators exhibit a remarkable ability to maintain a homeostatic intracellular Ca2+ environment. Compared with cells from non-hibernators, hibernator cells are characterized by downregulation of the activity of Ca2+ channels in the cell membrane, which helps to prevent excessive Ca2+ entry. Concomitantly, sequestration of

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Liu, Jiaqi, Naijia Liu, Yameng Xu, et al. "Bioresorbable shape-adaptive structures for ultrasonic monitoring of deep-tissue homeostasis." Science 383, no. 6687 (2024): 1096–103. http://dx.doi.org/10.1126/science.adk9880.

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Monitoring homeostasis is an essential aspect of obtaining pathophysiological insights for treating patients. Accurate, timely assessments of homeostatic dysregulation in deep tissues typically require expensive imaging techniques or invasive biopsies. We introduce a bioresorbable shape-adaptive materials structure that enables real-time monitoring of deep-tissue homeostasis using conventional ultrasound instruments. Collections of small bioresorbable metal disks distributed within thin, pH-responsive hydrogels, deployed by surgical implantation or syringe injection, allow ultrasound-based mea

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Davies, Kelvin J. A. "Free radicals and adaptive homeostasis in exercise." Free Radical Biology and Medicine 96 (July 2016): S2—S3. http://dx.doi.org/10.1016/j.freeradbiomed.2016.04.166.

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12

E.I., Bon, Maksimovich N.Ye., Betenya D.A., Yasyukevich A.I, and Otlivanchik N.I. "Hypothalamic Mechanisms of Vegetative Function Homeostasis." Universal Library of Biological Sciences 01, no. 01 (2024): 01–13. https://doi.org/10.70315/uloap.ulbsc.2024.0101001.

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Hypothalamic mechanisms of homeostatic reactions provide regulation of such vital physiological constants as osmotic pressure, ionic balance, humoral and hormonal activity of blood, sugar content and concentration of gases in blood, blood pressure, body temperature and etc. Numerous neurophysiological research are devoted to the study of the role of the hypothalamus in the regulation of the cardiovascular system, respiration, digestion, endocrine system, in the regulation of sleep and wakefulness, emotional and motivational reactions, metabolism, thermoregulation, etc. The hypothalamic area is

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Tumanyan, S. S., S. V. Tumanyan, and E. A. Udovenko. "Adaptive homeostasis in pregnant women with moderate preeclampsia." Voprosy ginekologii, akušerstva i perinatologii 20, no. 4 (2021): 64–68. http://dx.doi.org/10.20953/1726-1678-2021-4-64-68.

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Objective. To study the features of adaptive homeostasis in women with normal pregnancy and moderate preeclampsia (MPE). Patients and methods. Sixty-eight pregnant women were under study. General non-specific adaptive responses and adaptive cardiovascular responses were examined in 30 women with normal pregnancy and in 38 women with MPE. Results. Both general and organ adaptive responses were found to have a close correlation with the course of labor, the immediate postpartum period, and perinatal outcomes. Identification of general non-specific adaptive responses in the group of patients with

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Пальцын, А. А., and Н. Б. Свиридкина. "Age and homeostasis." Nauchno-prakticheskii zhurnal «Patogenez», no. 2() (June 16, 2020): 79–86. http://dx.doi.org/10.25557/2310-0435.2020.02.79-86.

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Гомеостаз - способность организма сохранять достаточное для жизни постоянство структуры и функции. Противоречие заключается в том, что суть жизни - это неизбежное изменение структуры и функции. Наиболее распространенный нарушитель гомеостаза - оксидативный стресс. В нейтрализации его действия участвует множество генов, включаемых транскрипционными факторами Nrf2, NFκB, TFAM, и PGC1α. Адаптивный ответ развивается не только на оксидативный стресс, но и на тепловой шок, гликемический стресс, холодовой шок, осмотический стресс, переутомление, голодание, механический стресс, антигенное воздействие,

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Loschko, Jakob, Heidi A. Schreiber, Gereon J. Rieke, et al. "Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation." Journal of Experimental Medicine 213, no. 4 (2016): 517–34. http://dx.doi.org/10.1084/jem.20160062.

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Conventional dendritic cells (cDCs) play an essential role in host immunity by initiating adaptive T cell responses and by serving as innate immune sensors. Although both innate and adaptive functions of cDCs are well documented, their relative importance in maintaining immune homeostasis is poorly understood. To examine the significance of cDC-initiated adaptive immunity in maintaining homeostasis, independent of their innate activities, we generated a cDC-specific Cre mouse and crossed it to a floxed MHC class II (MHCII) mouse. Absence of MHCII on cDCs resulted in chronic intestinal inflamma

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Princiotta Cariddi, Lucia, Marco Mauri, Marco Cosentino, Maurizio Versino, and Franca Marino. "Alzheimer’s Disease: From Immune Homeostasis to Neuroinflammatory Condition." International Journal of Molecular Sciences 23, no. 21 (2022): 13008. http://dx.doi.org/10.3390/ijms232113008.

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Alzheimer’s Disease is the most common cause in the world of progressive cognitive decline. Although many modifiable and non-modifiable risk factors have been proposed, in recent years, neuroinflammation has been hypothesized to be an important contributing factor of Alzheimer’s Disease pathogenesis. Neuroinflammation can occur through the combined action of the Central Nervous System resident immune cells and adaptive peripheral immune system. In the past years, immunotherapies for neurodegenerative diseases have focused wrongly on targeting protein aggregates Aβ plaques and NFT treatment. Th

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Honda, Kenya, and Dan R. Littman. "The microbiota in adaptive immune homeostasis and disease." Nature 535, no. 7610 (2016): 75–84. http://dx.doi.org/10.1038/nature18848.

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18

Davies, K. J. A. "COMPROMISED REDOX REGULATION OF ADAPTIVE HOMEOSTASIS IN AGING." Innovation in Aging 2, suppl_1 (2018): 220. http://dx.doi.org/10.1093/geroni/igy023.811.

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19

Pomatto, Laura C. D., and Kelvin J. A. Davies. "The role of declining adaptive homeostasis in ageing." Journal of Physiology 595, no. 24 (2017): 7275–309. http://dx.doi.org/10.1113/jp275072.

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Pomatto, Laura C. D., John Tower, and Kelvin J. A. Davies. "Sexual Dimorphism and Aging Differentially Regulate Adaptive Homeostasis." Journals of Gerontology: Series A 73, no. 2 (2017): 141–49. http://dx.doi.org/10.1093/gerona/glx083.

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Curran, S. "DECLINE OF ADAPTIVE HOMEOSTASIS & HORMESIS IN AGING." Innovation in Aging 2, suppl_1 (2018): 428–29. http://dx.doi.org/10.1093/geroni/igy023.1605.

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22

Gastelum, Cassandra, Lynnea Perez, Jennifer Hernandez, et al. "Adaptive Changes in the Central Control of Energy Homeostasis Occur in Response to Variations in Energy Status." International Journal of Molecular Sciences 22, no. 5 (2021): 2728. http://dx.doi.org/10.3390/ijms22052728.

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Energy homeostasis is regulated in coordinate fashion by the brain-gut axis, the homeostatic energy balance circuitry in the hypothalamus and the hedonic energy balance circuitry comprising the mesolimbcortical A10 dopamine pathway. Collectively, these systems convey and integrate information regarding nutrient status and the rewarding properties of ingested food, and formulate it into a behavioral response that attempts to balance fluctuations in consumption and food-seeking behavior. In this review we start with a functional overview of the homeostatic and hedonic energy balance circuitries;

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23

Alekseev, M. A., E. E. Alekseev, E. V. Freуdina, and A. A. Tropin. "Parametrical Robustness as Technological and Financial Tool for Management of Economics Systems." Vestnik NSUEM, no. 4 (December 29, 2019): 143–60. http://dx.doi.org/10.34020/2073-6495-2019-4-143-160.

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The relevance of the development of research on the parametrization of homeostasis as a special information structure of robust control introduced into economic systems to ensure robust stability of their activities is substantiated. The principles of designing homeostasis for managing complex open systems in a multisubjective environment filled with uncertainty are given. The experience of using homeostasis in economic theory is generalized. An approach to the design of adaptive homeostasis of an economic system that combines parameters-indicators of its activity and the state of a multisubje

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Merad, Miriam, and Markus G. Manz. "Dendritic cell homeostasis." Blood 113, no. 15 (2009): 3418–27. http://dx.doi.org/10.1182/blood-2008-12-180646.

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Abstract Dendritic cells (DCs) are a heterogeneous fraction of rare hematopoietic cells that coevolved with the formation of the adaptive immune system. DCs efficiently process and present antigen, move from sites of antigen uptake to sites of cellular interactions, and are critical in the initiation of immune responses as well as in the maintenance of self-tolerance. DCs are distributed throughout the body and are enriched in lymphoid organs and environmental contact sites. Steady-state DC half-lives account for days to up to a few weeks, and they need to be replaced via proliferating hematop

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25

Burke, Susan J., and J. Jason Collier. "Special Issue: Islet Inflammation and Metabolic Homeostasis." Metabolites 11, no. 2 (2021): 77. http://dx.doi.org/10.3390/metabo11020077.

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This special issue was commissioned to offer a source of distinct viewpoints and novel data that capture some of the subtleties of the pancreatic islet, especially in relation to adaptive changes that influence metabolic homeostasis [...]

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Kolesnik, Evgeniy Anatolyevich, and Marina Arkadyevna Derkho. "To the issue of animal adaptive homeostasis in the model of broiler chicken organism in the technological living environment." Agro-Industrial Complex of Russia 23, no. 5 (2016): 1011–15. https://doi.org/10.5281/zenodo.4405223.

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<strong>To the issue of animal adaptive homeostasis in the model of broiler chicken organism in the technological living environment</strong> <em><strong>E. A. Kolesnik, M. A. Derkho</strong></em> The characteristic of the animal adaptive homeostasis based on the model of broiler chicken organism <em>Gallus gallus</em> (Linnaeus, 1758) by cross Hubbard F15 of early ontogenesis in technological conditions due to the summation of research results of hematomorphological indicators, the elements of pituitary-thyroid-adrenocortical axis, the components of the protein and fat metabolism, as wel

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Ansaldo, Eduard, Leianna C. Slayden, Krystal L. Ching, et al. "Akkermansia muciniphila induces intestinal adaptive immune responses during homeostasis." Science 364, no. 6446 (2019): 1179–84. http://dx.doi.org/10.1126/science.aaw7479.

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Intestinal adaptive immune responses influence host health, yet only a few intestinal bacteria species that induce cognate adaptive immune responses during homeostasis have been identified. Here, we show that Akkermansia muciniphila, an intestinal bacterium associated with systemic effects on host metabolism and PD-1 checkpoint immunotherapy, induces immunoglobulin G1 (IgG1) antibodies and antigen-specific T cell responses in mice. Unlike previously characterized mucosal responses, T cell responses to A. muciniphila are limited to T follicular helper cells in a gnotobiotic setting, without app

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Gasteiger, Georg, Saskia Hemmers, Paula D. Bos, Joseph C. Sun, and Alexander Y. Rudensky. "IL-2–dependent adaptive control of NK cell homeostasis." Journal of Experimental Medicine 210, no. 6 (2013): 1179–87. http://dx.doi.org/10.1084/jem.20122571.

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Activation and expansion of T and B lymphocytes and myeloid cells are controlled by Foxp3+ regulatory T cells (T reg cells), and their deficiency results in a fatal lympho- and myeloproliferative syndrome. A role for T reg cells in the homeostasis of innate lymphocyte lineages remained unknown. Here, we report that T reg cells restrained the expansion of immature CD127+ NK cells, which had the unique ability to up-regulate the IL2Rα (CD25) in response to the proinflammatory cytokine IL-12. In addition, we observed the preferential accumulation of CD127+ NK cells in mice bearing progressing tum

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Kayama, H., and K. Takeda. "Regulation of intestinal homeostasis by innate and adaptive immunity." International Immunology 24, no. 11 (2012): 673–80. http://dx.doi.org/10.1093/intimm/dxs094.

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Pomatto, Laura C. D., and Kelvin J. A. Davies. "Adaptive homeostasis and the free radical theory of ageing." Free Radical Biology and Medicine 124 (August 2018): 420–30. http://dx.doi.org/10.1016/j.freeradbiomed.2018.06.016.

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Kaneko, Kota, Kenji Kamimoto, Atsushi Miyajima, and Tohru Itoh. "Adaptive remodeling of the biliary architecture underlies liver homeostasis." Hepatology 61, no. 6 (2015): 2056–66. http://dx.doi.org/10.1002/hep.27685.

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Loshakova, A. I., N. V. Tsygan, S. G. Zheleznyak, N. A. Brazhenko, and O. N. Brazhenko. "Change in homeostasis of the body and the outcome of tuberculosis in the treatment of antituberculous medicines." Bulletin of the Russian Military Medical Academy 20, no. 3 (2018): 95–99. http://dx.doi.org/10.17816/brmma12261.

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Fundamental research in the field of physiology revealed the important role of the state of homeostatic balance of the body in the emergence, development and outcome of human diseases, including granulomatous respiratory diseases- tuberculosis and sarcoidosis. To assess the homeostasis of the body in clinical conditions, various research methods are used - immunological, biochemical, hormonal and functional. However, in the daily work they can’t always be performed for technical and economic reasons. Proposed a new available diagnostics criterion of homeostasis based on the study of the quanti

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Brook, T. M., N. S. Menkova, and I. S. Baskakov. "THE EFFECT OF ANAEROBIC PHYSICAL ACTIVITY ON THE LEVEL OF CONSTANT POTENTIALS OF THE CEREBRAL CORTEX OF ATHLETES." Bulletin of Donetsk National University. Series А. Natural Sciences, no. 3 (September 13, 2024): 31–37. https://doi.org/10.5281/zenodo.13745208.

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The method of neuroenergetic mapping is used to assess cerebral homeostasis to a greater extent in medicine. In sports, this method is used unreasonably rarely, although it has diagnostic significance and can serve as a marker for assessing readiness for training and competitive activities, the adaptive capabilities of the athlete's body to physical exertion. 21 hockey athletes participated in the study. The level of constant potentials of the cerebral cortex (LCC) was measured before and after exercise. The results of the study recorded a significant increase in cerebral homeostasis after ana

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Cavanagh, Mary, and Tracy Hussell. "Innate-adaptive interactions provide stability in the homeostatic lung environment (87.16)." Journal of Immunology 184, no. 1_Supplement (2010): 87.16. http://dx.doi.org/10.4049/jimmunol.184.supp.87.16.

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Abstract The air is full of innocuous, but highly antigenic particles that are inhaled with every breath. In order to avoid the damage associated with an inflammatory response, lung-resident immune cells are kept under strict regulation and fail to respond to most inhaled antigens. Whilst the majority of cells in the airspaces are alveolar macrophages, many other cell types are present in the airspaces and interstitium. Interactions between lung-resident cells provide the basis for the suppression of immune responses; and the cytokines, chemokines and other factors that they secrete provide fu

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Loshakova, A. I., N. A. Brazhenko, S. G. Zheleznyak, O. N. Brazhenko, N. V. Tsygan, and S. G. Kuzmin. "Dynamics of homeostasis and the outcome of sarcoidosis of the respiratory system in the treatment of corticosteroids." Bulletin of the Russian Military Medical Academy 20, no. 3 (2018): 21–26. http://dx.doi.org/10.17816/brmma12219.

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The outcome of sarcoidosis of the respiratory system is closely linked to the state of homeostasis and reactivity. Monitoring their status is possible through immunological, biochemical and hormonal studies. Within common medical institutions re-executing these studies is not always possible for a number of reasons. Therefore, the research for the availability and informative criteria of homeostasis and reactivity state was initiated at the end of XIXth century and continues until now. At the Department of Phthisiopulmonology of the First St.-Petersburg state medical University Academy I. P. P

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Perrinet. "An Adaptive Homeostatic Algorithm for the Unsupervised Learning of Visual Features." Vision 3, no. 3 (2019): 47. http://dx.doi.org/10.3390/vision3030047.

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The formation of structure in the visual system, that is, of the connections between cellswithin neural populations, is by and large an unsupervised learning process. In the primary visualcortex of mammals, for example, one can observe during development the formation of cells selectiveto localized, oriented features, which results in the development of a representation in area V1 ofimages’ edges. This can be modeled using a sparse Hebbian learning algorithms which alternatea coding step to encode the information with a learning step to find the proper encoder. A majordifficulty of such algori

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Makhnvea, Natalia V., Natalia I. Syuch, and Nina A. Kuznetsova. "Nonspecific adaptive reactions in outpatients of dermatovenereological profile." Russian Journal of Skin and Venereal Diseases 24, no. 6 (2022): 553–63. http://dx.doi.org/10.17816/dv100773.

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BACKGROUND: Changes in the morphological composition of the blood are among the most important criteria for diagnosing and predicting the course of diseases, allowing to assess the physiological state of the body. Calculated indices that can catch minimal changes in the indicators of the leukocyte blood formula in the early stages of the development of the pathological process make it possible to judge complex changes, sometimes imperceptible during the clinical examination of the patient. A well-known method characterizing the state of homeostasis is a method for assessing the state of homeos

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Poggi, Alessandro. "10th Anniversary of Cells: Advances in Cellular Immunology—Regulation of Autoimmune Response and Antitumor Reactivity: Are They Two Side of the Same Coin?" Cells 11, no. 24 (2022): 4122. http://dx.doi.org/10.3390/cells11244122.

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Vertkin, Irena, Boaz Styr, Edden Slomowitz, et al. "GABAB receptor deficiency causes failure of neuronal homeostasis in hippocampal networks." Proceedings of the National Academy of Sciences 112, no. 25 (2015): E3291—E3299. http://dx.doi.org/10.1073/pnas.1424810112.

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Stabilization of neuronal activity by homeostatic control systems is fundamental for proper functioning of neural circuits. Failure in neuronal homeostasis has been hypothesized to underlie common pathophysiological mechanisms in a variety of brain disorders. However, the key molecules regulating homeostasis in central mammalian neural circuits remain obscure. Here, we show that selective inactivation of GABAB, but not GABAA, receptors impairs firing rate homeostasis by disrupting synaptic homeostatic plasticity in hippocampal networks. Pharmacological GABAB receptor (GABABR) blockade or genet

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40

Davies, Kelvin J. A. "Age and sex determine the effectiveness of redox adaptive homeostasis." Free Radical Biology and Medicine 165 (March 2021): 3. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.238.

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Polverino, Francesca. "Adaptive immune responses and protein homeostasis in COPD: the immunoproteasome." European Respiratory Journal 59, no. 3 (2022): 2102557. http://dx.doi.org/10.1183/13993003.02557-2021.

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Gallagher, Pamela S., Madeline Larkin, Gobi Thillainadesan, et al. "Iron homeostasis regulates facultative heterochromatin assembly in adaptive genome control." Nature Structural & Molecular Biology 25, no. 5 (2018): 372–83. http://dx.doi.org/10.1038/s41594-018-0056-2.

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Faulkner, Melinda J., and John D. Helmann. "Peroxide Stress Elicits Adaptive Changes in Bacterial Metal Ion Homeostasis." Antioxidants & Redox Signaling 15, no. 1 (2011): 175–89. http://dx.doi.org/10.1089/ars.2010.3682.

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44

Bronsart, Laura L., and Christopher H. Contag. "A role of the adaptive immune system in glucose homeostasis." BMJ Open Diabetes Research & Care 4, no. 1 (2016): e000136. http://dx.doi.org/10.1136/bmjdrc-2015-000136.

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Davies, Kelvin J. A. "Oxidative Stress and the Decline of Adaptive Homeostasis in Aging." Free Radical Biology and Medicine 86 (September 2015): S12. http://dx.doi.org/10.1016/j.freeradbiomed.2015.07.053.

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46

Wirths, Stefan, Stefanie Bugl, and Hans-Georg Kopp. "Neutrophil homeostasis and its regulation by danger signaling." Blood 123, no. 23 (2014): 3563–66. http://dx.doi.org/10.1182/blood-2013-11-516260.

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AbstractHematopoiesis in general is demand driven and adaptive, but in contrast to erythropoiesis or thrombocytopoiesis, our knowledge on how neutrophil production is adapted to individual needs remains incomplete. Recently, neutrophil homeostasis has been shown to depend on danger receptors, macrophages, and even circadian rhythms. Puzzle pieces for a broader view of neutrophil homeostasis accumulate, and we will herein try to put seemingly contradictory evidence in a perspective of neutrophil homeostasis and emergency granulopoiesis determined by innate immunologic signaling.

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Zhang, Vida, Elizabeta Nemeth, and Airie Kim. "Iron in Lung Pathology." Pharmaceuticals 12, no. 1 (2019): 30. http://dx.doi.org/10.3390/ph12010030.

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The lung presents a unique challenge for iron homeostasis. The entire airway is in direct contact with the environment and its iron particulate matter and iron-utilizing microbes. However, the homeostatic and adaptive mechanisms of pulmonary iron regulation are poorly understood. This review provides an overview of systemic and local lung iron regulation, as well as the roles of iron in the development of lung infections, airway disease, and lung injury. These mechanisms provide an important foundation for the ongoing development of therapeutic applications.

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48

Korfei, Martina, BreAnne MacKenzie, and Silke Meiners. "The ageing lung under stress." European Respiratory Review 29, no. 156 (2020): 200126. http://dx.doi.org/10.1183/16000617.0126-2020.

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Healthy ageing of the lung involves structural changes but also numerous cell-intrinsic and cell-extrinsic alterations. Among them are the age-related decline in central cellular quality control mechanisms such as redox and protein homeostasis. In this review, we would like to provide a conceptual framework of how impaired stress responses in the ageing lung, as exemplified by dysfunctional redox and protein homeostasis, may contribute to onset and progression of COPD and idiopathic pulmonary fibrosis (IPF). We propose that age-related imbalanced redox and protein homeostasis acts, amongst oth

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Kolesnik, E. A., та M. A. Derkho. "To the Problem of Physiological Adaptive Homeostasis In the Model of the Organism of Warm-Blooded Animals (а review)". Bulletin of Chelyabinsk State University. Education and Healthcare 4, № 12 (2020): 15–30. https://doi.org/10.6084/m9.figshare.16866820.v2.

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The purpose of the work is a review theoretical description of some biophysical mechanisms of physiological adaptation of homeostasis of a homoiothermal animal in relation to the conditions of the environment of vital activity. Erwin Schrödinger, for the first time, described negentropy as the leading criterion for distinguishing a living system from an don’t living. It was figuratively noted that the biosystem «feeds on negative entropy», attracting the flow of negentropy (negative entropy) to itself (metabolism), which it produces (anabolism and catabolism) and thus ma

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Li, Qian, Yan Gao, and An Yang. "Sulfur Homeostasis in Plants." International Journal of Molecular Sciences 21, no. 23 (2020): 8926. http://dx.doi.org/10.3390/ijms21238926.

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Sulfur (S) is an essential macronutrient for plant growth and development. S is majorly absorbed as sulfate from soil, and is then translocated to plastids in leaves, where it is assimilated into organic products. Cysteine (Cys) is the first organic product generated from S, and it is used as a precursor to synthesize many S-containing metabolites with important biological functions, such as glutathione (GSH) and methionine (Met). The reduction of sulfate takes place in a two-step reaction involving a variety of enzymes. Sulfate transporters (SULTRs) are responsible for the absorption of SO42−

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