Academic literature on the topic 'ADC gene'

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Journal articles on the topic "ADC gene"

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Lukashev, Alexander N., Olga E. Ivanova, Tatiana P. Eremeeva, and Richard D. Iggo. "Evidence of frequent recombination among human adenoviruses." Journal of General Virology 89, no. 2 (2008): 380–88. http://dx.doi.org/10.1099/vir.0.83057-0.

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Genome stability is a prerequisite for the production and use of adenoviruses for therapy of genetic diseases and cancer. To test the premise that the adenoviral genome is stable, the phylogenetic relationships of 16 adenovirus C (AdC) field isolates were studied in four genome regions: hexon, fiber, polymerase and E1A. The phylogenetic relationships in the fiber gene concurred with those in the hexon region. In contrast, the non-structural regions had marks of frequent recombination, to the point that an isolate of one serotype could contain non-structural proteins that were identical to the
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Lashford, L. "Gene therapy for cancers." Archives of Disease in Childhood 71, no. 6 (1994): 485–87. http://dx.doi.org/10.1136/adc.71.6.485.

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Scambler, P. J. "The cystic fibrosis gene." Archives of Disease in Childhood 64, no. 12 (1989): 1647–48. http://dx.doi.org/10.1136/adc.64.12.1647.

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McLeish, S., and S. W. Turner. "Gene environment interactions in asthma." Archives of Disease in Childhood 92, no. 11 (2007): 1032–35. http://dx.doi.org/10.1136/adc.2006.112185.

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Coutelle, C., N. Caplen, S. Hart, C. Huxley, and R. Williamson. "Gene therapy for cystic fibrosis." Archives of Disease in Childhood 68, no. 4 (1993): 437–40. http://dx.doi.org/10.1136/adc.68.4.437.

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Kinnon, C., and R. J. Levinsky. "Somatic gene therapy for genetic disease." Archives of Disease in Childhood 65, no. 1 (1990): 72–73. http://dx.doi.org/10.1136/adc.65.1.72.

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Tisdale, John F., Robert E. Donahue, Naoya Uchida, et al. "A Single Dose of CD117 Antibody Drug Conjugate Enables Autologous Gene-Modified Hematopoietic Stem Cell Transplant (Gene Therapy) in Nonhuman Primates." Blood 134, Supplement_1 (2019): 610. http://dx.doi.org/10.1182/blood-2019-125968.

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Autologous hematopoietic stem cell transplantation (Auto-HSCT) with gene-modification techniques represents a potential cure for multiple genetic blood diseases. Despite its broad curative potential, auto-gene modified HSCT is currently limited due to morbidity/mortality from cytotoxic chemotherapy-based conditioning, including risks of secondary malignancies, organ toxicity, and infertility. To overcome these limitations, we have developed antibody drug conjugates (ADC) targeting CD117 (C-KIT) to specifically deplete the hematopoietic stem and progenitor cells (HSPC) prior to auto-gene modifi
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Jaffe, A., A. Bush, D. M. Geddes, and E. W. F. W. Alton. "Prospects for gene therapy in cystic fibrosis." Archives of Disease in Childhood 80, no. 3 (1999): 286–89. http://dx.doi.org/10.1136/adc.80.3.286.

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Qasim, W., H. Bobby Gaspar, and A. J. Thrasher. "Update on clinical gene therapy in childhood." Archives of Disease in Childhood 92, no. 11 (2007): 1028–31. http://dx.doi.org/10.1136/adc.2006.108787.

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Kurniawati, Siti, and Sri Hartati. "Optimization Of The Annealing Temperature With Degenerate Primer For Amplification Of Arginine Decarboxylase (ADC) Fragment Gene From Genomic DNA of Maluku Tenggara Local Cassava." Jurnal ILMU DASAR 19, no. 2 (2018): 135. http://dx.doi.org/10.19184/jid.v19i2.6261.

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Arginine decarboxylase (ADC) is a key enzyme responsible for polyamines biosynthesis and has been shown to increase resistance to biotic and abiotic stress. Cassava (Manihot esculenta Crantz.) is able to grow and produce storage roots well on marginal land. The purpose of this study was to optimize annealing temperature of primers in PCR reaction to amplify candidate cassava ADC gene fragments. Annealing temperature is a crucial factor in PCR reaction affecting product (gene fragments) specificity. Four pairs of primers; MeADC1, MeADC2, MeADC3, andMeADC4, were designed using degenerate method
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Dissertations / Theses on the topic "ADC gene"

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Lopes, Bruno Silvester. "Role of insertion sequences in the control of antibiotic resistance in Acinetobacter baumannii." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/6500.

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Acinetobacter baumannii is an emerging multiresistant pathogen increasingly known to cause infections in the immuno-compromised patients. Carbapenems and colistin are considered to be the last resorts in treatment of infections involving multidrug resistant strains of A. baumannii. Resistance to carbapenems is well known due to the presence of intrinsic carbapenemase gene blaOXA-51-like, which may be governed by insertion elements, or by acquired carbapenemases like blaOXA-23-like, blaOXA-58-like or blaOXA-40-like genes, most of which are frequently associated with insertion elements. The acqu
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Rice, Kim. "Functional analysis of the HOX11 target genes ALDH1A1 and FHL1 /." Access via Murdoch University Digital Theses Project, 2004. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20051012.93820.

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com, Darcelle@gmail, and Darcelle Natalie Dixon. "Identification of Downstream Target Genes of the T-cell Oncoprotein HOX11 by Global Gene Expression Profiling." Murdoch University, 2004. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20040929.143814.

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HOX11 is a homeodomain transcription factor that has been implicated in leukaemic transformation associated with T-cell acute lymphoblastic leukaemia (T-ALL). Its role in leukaemogenesis remains enigmatic, nevertheless, in vitro and in vivo studies have provided additional evidence supporting the role of HOX11 as an oncogene. The mechanism by which HOX11 transforms cells is yet to be elucidated, however, HOX11 has been postulated to function by binding regulatory elements within the promoter regions of specific target genes in order to control gene transcription. The identification of transcri
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DUPRE, PATRICIA. "Transformation genetique de ginkgo biloba via agrobacterium tumefaciens : application au transfert des genes rol abc d'agrobacterium rhizogenes (doctorat : biotechnologies vegetales)." Amiens, 1999. http://www.theses.fr/1999AMIEP067.

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Sundholm, James, and n/a. "Analysis of Specific Migraine Candidate Genes Mapping to Human Chromosome 1." Griffith University. School of Health Science, 2003. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20030829.153348.

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Migraine, comprised of migraine with aura (MA) and migraine without aura (MO), is a painful neurovascular disease, affecting approximately 16% of the general population. It is characterised by a wide variety of symptoms including headache, nausea and vomiting, and photo- and phonophobia. The disorder is complex involving not only multiple genes, but also specific environmental factors, which can induce attacks in genetically predisposed individuals. Hyperhomocysteinaemia is a known risk factor for cerebrovascular, peripheral vascular and coronary heart disease. The Methylenetetrahydrofolate Re
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Calero, M. "Novel gene therapy strategies for ADA deficiency using AAV vectors or gene editing." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1563615/.

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LaPointe, Lawrence C., and larry lapointe@flinders edu au. "Gene expression biomarkers for colorectal neoplasia." Flinders University. School of Medicine, 2009. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20091011.090028.

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The aim of this research was to assemble sufficient experimental evidence about candidate gene transcript expression changes between non-neoplastic and neo- plastic colorectal tissues to justify future assay development involving promis- ing leads. To achieve this aim, this thesis explores the hypothesis that gene expression-based biomarkers can be used to accurately discriminate colorectal neoplastic tissues from non-neoplastic controls. This hypothesis was tested by first analysing multiple, large, quality controlled data sets comprising gene expression measurements across colorectal phenot
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Hunter, Michael. "Molecular investigations of the CMT4D gene N-myc downstream-regulated gene 1 (NDRG1)." University of Western Australia. School of Medicine and Pharmacology, 2006. http://theses.library.uwa.edu.au/adt-WU2007.0034.

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[Truncated abstract] Hereditary Motor and Sensory Neuropathy Lom (HMSNL) is a severe autosomal recessive peripheral neuropathy, the most common form of demyelinating Charcot-Marie-Tooth (CMT) disease in the Roma (Gypsy) population. The mutated gene, N-myc downstream-regulated gene 1 (NDRG1) on chromosome 8q24, is widely expressed and has been implicated in a wide range of processes and pathways. In this study we have aimed to assess the overall contribution of this gene to the pathogenesis of peripheral neuropathies, in cases where the most common causes of CMT disease havebeen excluded, as we
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Cassereau, Catherine. "Le chromosome mitochondrial." Paris 5, 1988. http://www.theses.fr/1988PA05P072.

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Nasa, Zeyad, and nasa zeyad@med monash edu au. "Characterization of the Rat Relaxin-like Factor Gene." RMIT University. Medical Sciences, 2006. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080514.100729.

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Relaxin-like factor (RLF), also known as Leydig insulin-like peptide (Ley-I-L) or Insulin 3 (INSL3), is a newly characterized member of the insulin peptide family. Amino acid sequence homology revealed that RLF is more closely related to relaxin than any other insulin-like hormones. The main aim of this thesis was to sequence the rat RLF (Relaxin-like factor) gene and determine the structure and organisation of the gene. Secondly to compare the structural organisation of the rat RLF/JAK3 genomic region with that of the mouse and human, using bioinformatic databases. Thirdly to further inves
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Books on the topic "ADC gene"

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Genes IX. 9th ed. McGraw-Hill, 2008.

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The ABCs of gene cloning. Chapman & Hall, 1997.

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Genes. 2nd ed. Wiley, 1985.

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Lewin, Benjamin. Genes. 3rd ed. Wiley, 1987.

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Genes. 3rd ed. Wiley, 1987.

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Lewin, Benjamin. Genes V. Oxford University Press, 1994.

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Lewin, Benjamin. Genes V. Oxford University Press, 1994.

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Genes V. Oxford University Press, 1994.

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Lewin, Benjamin. Genes V. 5th ed. Oxford University Press, 1994.

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Lewin, Benjamin. Genes V. Oxford University Press, 1994.

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Book chapters on the topic "ADC gene"

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Berghammer, H., M. Schweiger, and B. Auer. "Structure and Organization of the Mouse pADPRT Gene." In ADP-Ribosylation Reactions. Springer New York, 1992. http://dx.doi.org/10.1007/978-1-4419-8718-1_10.

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Santulli, Francesca. "Chapter 8. Context and genre in judicial argumentation." In Argumentation across Communities of Practice. John Benjamins Publishing Company, 2017. http://dx.doi.org/10.1075/aic.10.09san.

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Guis, M., T. Bouquin, H. Zegzouti, et al. "Differential Expression of ACC Oxidase Genes in Melon and Physiological Characterization of Fruit Expressing an Antisense ACC Oxidase Gene." In Biology and Biotechnology of the Plant Hormone Ethylene. Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-011-5546-5_40.

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Zahradka, Peter, and Lorraine Yau. "ADP-ribosylation and gene expression." In ADP-Ribosylation: Metabolic Effects and Regulatory Functions. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2614-8_12.

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Bankiewicz, Krystof, Waldy San Sebastian, Lluis Samaranch, and John Forsayeth. "GDNF and AADC Gene Therapy for Parkinson’s Disease." In Translational Neuroscience. Springer US, 2016. http://dx.doi.org/10.1007/978-1-4899-7654-3_4.

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Ferrero, Enza, and Fabio Malavasi. "A Natural History of the Human CD38 Gene." In Cyclic ADP-Ribose and NAADP. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0269-2_4.

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Sheehy, R. E., V. Ursin, S. Vanderpan, and W. R. Hiatt. "Expression of a Bacterial ACC Deaminase Gene in Tomato." In Cellular and Molecular Aspects of the Plant Hormone Ethylene. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-017-1003-9_22.

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Ghani, Q. Perveen, M. Zamir Hussain, Jincai Zhang, and Thomas K. Hunt. "Control of Procollagen Gene Transcription and Prolyl Hydroxylase Activity by Poly(ADP-Ribose)." In ADP-Ribosylation Reactions. Springer New York, 1992. http://dx.doi.org/10.1007/978-1-4419-8718-1_36.

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Peter, Gary, William Rottmann, Takahide Sato, et al. "ACC Synthase Genes in Zucchini and Tomato." In Plant Molecular Biology 2. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3304-7_73.

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Jacob, Samson T., Jane F. Mealey, and Rabinder N. Kurl. "Role of Poly(ADP-Ribose) Polymerase in Ribosomal RNA Gene Transcription." In ADP-Ribose Transfer Reactions. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4615-8507-7_36.

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Conference papers on the topic "ADC gene"

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Khrennikov, Andrei. "P-adic Dynamical Representation of Gene Expression." In FOUNDATIONS OF PROBABILITY AND PHYSICS - 4. AIP, 2007. http://dx.doi.org/10.1063/1.2713475.

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Singh, Abhyudai, and Joao Pedro Hespanha. "Scaling of stochasticity in gene cascades." In 2008 American Control Conference (ACC '08). IEEE, 2008. http://dx.doi.org/10.1109/acc.2008.4586914.

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Sami Fadali, M., and M. Savageau. "Gene regulation models and evolution." In 2009 American Control Conference. IEEE, 2009. http://dx.doi.org/10.1109/acc.2009.5160562.

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Siegal-Gaskins, Dan, Vincent Noireaux, and Richard M. Murray. "Biomolecular resource utilization in elementary cell-free gene circuits." In 2013 American Control Conference (ACC). IEEE, 2013. http://dx.doi.org/10.1109/acc.2013.6580053.

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High, K. A., J. P. Evans, J. L. Ware, D. W. Stafford, and H. R. Roberts. "HEMOPHILIA B IN CANINES IS DUE TO A POST-TRANSCRIPTIONAL DEFECT." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644017.

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Factor IX is a vitamin K dependent plasma proteinsynthesized in the liver; a deficiency of Factor IX results in hemophilia B. An animal model for hemophilia B exists in dogs; affected animals have severe disease, with activity levels of less than 1%. The purpose of the current study is to determine the molecular basis of canine hemophilia. In previous work, we had shown that the Factor IX gene in hemophilic dogs appeared to be at least partly intact; thus, genomic DNA from normal, carrier and hemophilic dogs, when probed with sequences from the 4th, 7th, and 8th exons of the human gene, gave i
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Qian, Yili, and Domitilla Del Vecchio. "Effective interaction graphs arising from resource limitations in gene networks." In 2015 American Control Conference (ACC). IEEE, 2015. http://dx.doi.org/10.1109/acc.2015.7172024.

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Smith, Madeline, and Abhyudai Singh. "Noise suppression by stochastic delays in negatively autoregulated gene expression." In 2020 American Control Conference (ACC). IEEE, 2020. http://dx.doi.org/10.23919/acc45564.2020.9147896.

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Giordano, Giulia, Elisa Franco, and Richard M. Murray. "Feedback architectures to regulate flux of components in artificial gene networks." In 2013 American Control Conference (ACC). IEEE, 2013. http://dx.doi.org/10.1109/acc.2013.6580572.

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Ghusinga, Khem Raj, and Abhyudai Singh. "Effect of gene-expression bursts on stochastic timing of cellular events." In 2017 American Control Conference (ACC). IEEE, 2017. http://dx.doi.org/10.23919/acc.2017.7963265.

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Munsky, Brian, and Mustafa Khammash. "Computation of switch time distributions in stochastic gene regulatory networks." In 2008 American Control Conference (ACC '08). IEEE, 2008. http://dx.doi.org/10.1109/acc.2008.4586911.

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Reports on the topic "ADC gene"

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Soldatenkov, Viatcheslav A. Gene Therapy for Prostate Cancer Radiosensitization Using Mutant Poly (ADP-Ribose) Polymerase. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada414783.

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Jarrett, Christy R. A New APC-Like Gene Involved in Regulation of B-Catenin/LEF. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada404820.

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Jarrett, Christy. A New APC-like Gene Involved in Regulation of B-catenin/LEF. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada390791.

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Jarrett, Christy R. A New APC-Like Gene Involved in Regulation of Beta-Catenin/LEF Signaling. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada409414.

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Okita, T. W. [Enhancement of photoassimilate utilization by manipulation of ADP-glucose pyrophosphorylase gene]. Final progress report. Office of Scientific and Technical Information (OSTI), 1999. http://dx.doi.org/10.2172/334250.

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Jack Preiss. Structure Function Relationships of ADP-Glucose Pyrophosphorylase and Branching Enzyme: Manipulation of Their Genes for Alteration of Starch Quanlity and Quantity. Office of Scientific and Technical Information (OSTI), 2006. http://dx.doi.org/10.2172/876435.

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Capturando genes en movimiento. La utilización de la crio-microscopía electrónica para estudiar la transposición del ADN. Sociedad Española de Bioquímica y Biología Molecular, 2021. http://dx.doi.org/10.18567/sebbmdiv_anc.2021.06.1.

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