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1

Mukai, Susumu. "Vicissitude of Curetted Adenoid Vegetations." International Journal of Clinical Medicine 04, no. 05 (2013): 251–56. http://dx.doi.org/10.4236/ijcm.2013.45044.

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2

Revyakina, V. A., T. I. Garaschenko, and A. M. Samohvat. "Allergic rhinitis or adenoid vegetations/adenoids. Where is the truth?" Russian Journal of Allergy 11, no. 1 (December 15, 2014): 59–63. http://dx.doi.org/10.36691/rja568.

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Background. Children with frequent acute respiratory viral infections and clinical symptoms of the upper respiratory tract are often prescribed unwarranted surgical treatment. The aim of this study was to assess the allergic reactivity in children with frequent acute respiratory viral infections and obstructed nasal breathing. Methods. The study included 48 children aged from 2 to 7 years old, 29 boys and 19 girls. Clinical examination including anamnesis morby and family anamnesis of allergy, endoscopic examination of the nose and nasopharynx, total and allergen-specific IgE determination were performed. Results. In 87,5% of children with frequent acute respiratory viral infections and previously diagnosed adenoid hypertrophy degree II-III with a block of auditory tube pharyngeal mouths or hypertrophy of adenoid hypertrophy with II degree pipe rollers, pipe tonsils, allergic rhinitis (?) hypersensitivity to house dust mites and in 54,1% to pollen was detected. In 25,0% of children allergen-specific IgE antibodies to food allergens (cow’s milk, nuts, grains, pears) were identified. 33,3% of children had high levels of allergen-specific IgE antibodies to cats and dogs epidermidis. Conclusion. Children with frequent acute respiratory viral infections and nasal obstruction require allergist survey to develop treatment strategies.
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3

Davcheva-Chakar, Marina, Ana Kaftandzhieva, and Beti Zafirovska. "Adenoid Vegetations – Reservoir of Bacteria for Chronic Otitis Media with Effusion and Chronic Rhinosinusitis." PRILOZI 36, no. 3 (December 1, 2015): 71–76. http://dx.doi.org/10.1515/prilozi-2015-0080.

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Abstract Introduction: Otitis media and rhinosinusitis are commonly encountered illnesses in pediatric population. Literature reports have documented the association between the occurrence of these two conditions and even their almost identical microbiological findings. Until recently, the key factor in the association of these two conditions was considered to be the hypertrophic adenoid tissue, but within the past few years there have been evidences in the literature about the presence of bacterial biofilms on the adenoids suggesting biofilms to be also responsible for both conditions, chronic otitis media with effusion and chronic rhinosinusitis. Aim: The aim of this study was to make a microbiological analysis of the adenoid tissue specimens taken from patients with chronic otitis media with effusion and chronic or recurrent rhinosinusitis and to determine their potential for biofilms formation. Methods: After the surgical intervention, adenoidectomy, microbiological evaluation and analysis of the adenoid tissue specimens taken from 20 patients were made. Having in mind the disease history, chronic otitis media with effusion was diagnosed in all 20 patients and chronic rhinosinusitis in 9 patients. Results: The results obtained from the microbiological analyses showed many potentially pathogenic bacteria in the adenoids that were almost identical with the most common organisms incorporated in the etiopathogenesis of both conditions, in chronic otitis media with effusion and in chronic rhinosinusitis. In 7 (35%) patients Haemophylus influenzae was isolated, in 6 (30%) Streptococcus pneumoniae, in 4 (20%) Moraxella catаrrhalis, in 2 (10%) patients Staphylococcus aureus and in 1 (5%) patient Streptococcus pyogenes - group A was isolated. One bacterium was isolated from all adenoid vegetations, except in one case when two bacteria (Haemophylus influenzae and Staphylococcus aureus) were concurrently isolated. Conclusion: Our results have shown that the key role in adenoid vegetations in chronic otitis media with effusion and chronic rhinosinusitis is not only the mechanism of rhinopharyngeal obstruction, but also the presence of bacterial strains with a large potential for formation of biofilms adhered to their surface, especially in cases with symptoms of chronic otitis media with effusion and chronic rhinosinusitis that were resistant to antibiotic therapy.
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4

Kosakivska, I. A. "Diagnostics difficulties of adenoid vegetations in children." SOVREMENNAYA PEDIATRIYA, no. 5(93) (September 30, 2018): 11–13. http://dx.doi.org/10.15574/sp.2018.93.11.

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5

Kosakivska, I. A. "Auditory function in children with adenoid vegetations." Modern pediatrics. Ukraine, no. 2(106) (March 28, 2020): 8–11. http://dx.doi.org/10.15574/sp.2020.106.8.

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6

Anand, Shweta, and Mahesh Virupakshi Kattimani. "Adenoid Hypertrophy with Deviated Nasal Septum in Young Adults." Journal of Evolution of Medical and Dental Sciences 10, no. 36 (September 6, 2021): 3199–201. http://dx.doi.org/10.14260/jemds/2021/650.

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Adenoid hypertrophy is a common cause of nasal obstruction in children but relatively uncommon in adults, however adenoid hypertrophy in young adults is thought to be a persistence of untreated adenoid hypertrophy of childhood. This case series also notes that adenoid hypertrophy can be associated with deviated nasal septum. Coblation assisted endoscopic adenoidectomy usually has good result in adenoid clearance. Hence, routine endoscopic examination of nasopharynx helps in early diagnosis of adenoid hypertrophy and subsequent better management in young adults with complaints of nasal blockage. Nasopharyngeal vegetations were earlier described by Wilhelm Meyer in 1870 as forming part of Waldeyer’s ring of lymphoid tissue and he coined the term ‘adenoid’ to describe the same. In younger children, it has been thought that the adenoids may have an important role in development of an immunological memory. Physiologically it has been considered that hypertrophy of adenoid tissue occurs during 6 - 10 years and tend to regress and atrophy at 16 years. Grading of adenoid hypertrophy as described by Clemens et al. is as follows.1  Grade I: adenoid tissue filling 1/3rd. of the vertical height of choana.  Grade II: adenoid tissue filling up to 2/3rd of the vertical height of choana.  Grade III: from 2/3rd to nearly all but not completely filling the choana.  Grade IV: complete choanal obstruction We present three cases of adenoid hypertrophy with deviated nasal septums in adults who visited ENT outpatient department (OPD) at National Institute of Medical Sciences, Jaipur during COVID era of January 2021 to April 2021.
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7

Yaremchuk, Svetlana. "Hypertrophy of adenoid vegetation: causes and methods of treatment." OTORHINOLARYNGOLOGY 2-3(2) 2019, no. 2-3(2) 2019 (November 29, 2019): 63–66. http://dx.doi.org/10.37219/2528-8253-2019-2-63.

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Topicality: Nasal congestion, nasal breathing disorders and nasal discharge are the most common complaints that parents of ill children refer to an otolaryngologist and pediatrician. The prevalence of allergic pathology in patients with adenoid vegetation hypertrophy (AН) varies from 22 to 73% according to various authors. Aim: To determine the prevalence of allergic rhinitis among patients with hypertrophy of adenoid vegetations, a prospective study was conducted. Materials and methods: 50 children with hypertrophy of adenoid vegetation aged 4 to 14 years were examined. A comprehensive screening study to detect specific IgE sensitization to the most common inhalation and food allergens. Results: Sensitization to inhaled allergens was detected in 48% of cases. In 8% of cases it coincided with food with food allergy. Only food allergy was detected in 1 child (2%). Timely etiopathogenetic therapy with topical nasal corticosteroids in patients with AN will avoid relapses after adenoidectomy and normalize nasal breathing, and in some cases, avoid surgery.
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8

Yusupov, A. Sh. "Modern concept of etiopathogenesis, and treatment of nasal septum deformation combined with phyalystonic tongue hyperplasia in children." Health care of Tajikistan, no. 4 (February 3, 2022): 98–105. http://dx.doi.org/10.52888/0514-2515-2021-351-4-98-105.

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The article looks into the issues of etiopathogenesis and surgical treatment of children with deformity of the nasal septum, combined with hypertrophy of the nasopharyngeal tonsil. The article reflects the negative impact of adenoid vegetations and deformities of the nasal septum on the functional state of the nose, nasopharynx, and auditory tube in childhood. Analysis of the literature indicates, that there is no consensus regarding the surgical treatment of deformities of the nasal septum, combined with hypertrophy of the pharyngeal tonsil. The development of more effective methods of surgical treatment remains open.
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9

Alekseenko, Svetlana A., Svetlana A. Alekseenko, Svetlana A. Alekseenko, Sergey A. Karpishchenko, Irina G. Arustamyan, and Olga A. Stancheva. "Results of treatment for ronchopathy and obstructive sleep apnea syndrome in children with adenoid hypertrophy/vegetations." Consilium Medicum 23, no. 3 (2021): 222–25. http://dx.doi.org/10.26442/20751753.2021.3.200573.

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Introduction. There are various sleep disorders that are striking and depressing at the same time in their diversity. One of the urgent problems that modern medicine is working on is problems with breathing during sleep, including obstructive sleep apnea syndrome (OSAS). The prevalence of this disease in children ranges from 1.2 to 5.7%. Adenotomy is an absolute indication for children with OSAS and adenoid hypertrophy. Aim. To study the frequency of occurrence of the OSAS in patients admitted to their hospital otorhinolaryngological department of Rauhfus Children’s Municipal Multi-Specialty Clinical Center of High Medical Technology for the planned surgical treatment of adenoid hypertrophy; to assess the effect of adenotomy on the course of OSAS in children. Materials and methods. 42 children aged from 4 to 12 years were examined; all patients underwent computer-based pulse oximetry, rhinomanometry, and nasopharyngeal endoscopy. Results. After adenotomy, nasal patency in children improved significantly: from 289.26 ml/s to 467.00 ml/s; the mean night saturation and desaturation nadir values in children during treatment improved from 97.31 to 97.68% and from 87.58 to 91.52%, respectively; sleep apnea syndrome was detected in 88% of all patients; 1 month after adenotomy, in 66.67% of the examined children OSAS was not detected. Conclusion. Improvement of nasal breathing after adenotomy, confirmed by rhinomanometry data, contributes to improved sleep, as evidenced by the results of computer-based pulse oximetry.
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10

Bezshapochny, Sergey B., and Iryna S. Hychak. "Treatment of adenoid inflammation in children." OTORHINOLARYNGOLOGY, No2(4) 2021 (March 24, 2021): 60–65. http://dx.doi.org/10.37219/2528-8253-2021-2-60.

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Topicality: Inflammation of the adenoid tonsil is one of the common causes of ENT diseases in children. Among the causes of adenoiditis (nasopharyngitis) are infectious - viral and bacterial, allergic and gastric acid irritation in laryngopharyngeal reflux. The aim of our research was to study the effectiveness of topical application of a combination of xylometazoline hydrochloride 0.05% and miramistin 0.01% in the treatment of pediatric patients with pharyngeal tonsillitis. Materials and methods: We selected 60 patients aged 5 to 14 years with endoscopically confirmed adenoid vegetations of I-II stage with inflammation. Patients were divided into 2 groups – main and control. Patients in the control group received saline irrigation therapy 4 times a day, patients in the main group received saline lavage 4 times a day and intranasal administration of a combination of xylometazoline hydrochloride 0.05% and miramistin 0.01% three times a day for 7 days. Patient status was analyzed using a Likert scale questionnaire and objective endoscopic examination. Results: During treatment, a positive effect was observed in both groups. However, starting from the second visit (on the 3rd day of treatment) there was a faster decrease in symptoms in children of the main group compared to the control, on the 7th day the difference between the groups was subjective – 5.9 points, and objective – 2.5 points in favor of the main group. Therefore, intranasal administration of a combination of xylometazoline hydrochloride 0.05% and miramistin 0.01% helps reduce edema, redness, exudation, improves nasal breathing and in combination with saline irrigation therapy is an effective means for topical treatment of children with inflammatory diseases of the pharynx.
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11

Druzhikin, Leontiy V., Elena S. Druzhikina, Sergey A. Alekhin, Elena B. Artyushkova, Alexander A. Dolzhikov, Lyudmila M. Danilenko, and Vladimir Y. Provotorov. "Analysis of the Microorganism’s Sensitivity in Patients with Chronic Adenoiditis to Pharmacotherapy with Antibacterial Drugs." Journal of Computational and Theoretical Nanoscience 17, no. 9 (July 1, 2020): 4741–45. http://dx.doi.org/10.1166/jctn.2020.9371.

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Introduction: The prevalence of chronic pathology of the pharyngeal lymphatic system in preschool children reaches 45% and is mainly manifested by hypertrophy of adenoid vegetations, which in half of cases are combined with chronic inflammation, which, with repeated periods of exacerbation, leads to the development of severe chronic pathology of the upper respiratory tract. The role of microorganisms toleranceto pharmacological agents is widely proven in formation of chronic inflammatory disorders and demand correction of therapeutic schemes. Research tasks: The aim of this research was to study the microbial landscape of oropharynx in children who received surgical for adenoiditis and determine the sensitivity of the identified microorganisms to the pharmacotherapy with antibiotics. Material and Methods: We conducted a study of 1577 children aged from 1 year to 17 years and 11 months who received inpatient treatment at the otorhinolaryngological Department of the OO “Scientific and clinical multidisciplinary center named after Z. I. Kruglaya” in the city of Oryol in the period from 2015 to 2017 for hypertrophy of adenoid vegetations. The patients were divided into three groups based on the years of the study. The study of the oropharyngeal microbial association was performed by preparing a smear followed by Gram staining and bacterioscopy. Determination of the sensitivity of microorganisms to antibacterial drugs was performed by discdiffusion method. Results: We found in patients oropharynx microbial landscape with hypertrophy of chronic vegetation in dynamics over the period from 2015 to 2017, an increase in the number of opportunistic saprophytic flora was detected, which was observed against the background of a clear increase in the number of patients with this pathology an increase in the number of cases associated with saprophytic MRCA flora, represented mainly by Staphylococcus aureus, leads to a decrease in the effectiveness of conservative treatment of chronic adenoiditis, which is expressed in an increase in the number of adenotomies. Conclusion: The study revealed negative consequences of uncontrolled use of antibiotic therapy at the pre-hospital stage and irrational schemes of chemotherapy in hospital units, which is manifested in the growing resistance of microorganisms to both “old” antibacterial drugs and a decrease in sensitivity to pharmacotherapy with the latest generation of antibiotics and requires active revision of the schemes of antibiotic therapy and prevention.
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12

Friese, Karl-Heinz, Ulrike Feuchter, Rainer Lüdtke, and Hans Moeller. "Results of a randomised prospective double-blind clinical trial on the homeopathic treatment of adenoid vegetations." European Journal of General Practice 7, no. 2 (January 2001): 48–54. http://dx.doi.org/10.3109/13814780109048787.

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13

Chursina, A. M., and S. M. Pukhlik. "THE IMPORTANCE OF ALLERGIC FACTOR IN THE ETIOPATHOGENESIS OF CHRONIC ADENOIDITIS IN CHILDREN." Odes’kij medičnij žurnal (The Odessa Medical Journal), no. 6 (2022): 5–11. http://dx.doi.org/10.54229/2226-2008-2021-6-1.

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The article presents the features of the course of chronic adenoiditis in children with allergic rhinitis. Allergic diseases of the upper respiratory tract and pathology of the pharyngeal tonsil today remain one of the most common diseases in pediatric practice and their pathogenetic mechanisms are often interrelated. The choice of treatment mode for this group of children is currently being actively discussed. The aim of the study is scientific-literary and practical consideration of the problem of the influence of an allergic factor on the pathogenesis of nasopharyngeal tonsil hypertrophy as a cause of chronic adenoiditis in children. The study examined 30 children with stage 2 adenoid hypertrophy, including 18 boys and 12 girls. A number of authors insist on the need to prioritize conservative management, while more and more evidence is emerging that there may often be indications for surgery. The prevalence of allergic diseases and adenoid vegetations in childhood has determined the relevance of studying the research problem. It is established that adenoids in allergic rhinitis become a kind of shock organ, on the surface of which inhaled allergens are delayed. It has been determined that in allergic rhinitis removal of adenoids has the ability to improve the general condition of the patient and relieve symptoms (including nasal congestion) and reduce the risk of various chronic pathologies (namely chronic otitis), and in obstructive sleep apnea — reduce the risk of suffocation. The algorithm of management of children with pathology of the pharyngeal tonsil in concomitant allergic diseases, where the first stage it is necessary to recommend treatment by an allergist, and only in the ineffectiveness of conservative therapy to perform surgery. It has been shown that most of the studied children (60–70%) with stage II nasopharyngeal tonsil hypertrophy showed allergic rhinitis and elevated levels of anti-inflammatory cytokines, which indicates the relationship of the disease with inflammatory diseases of the nasopharynx and immune system. It is determined that the problems of correct diagnosis of the causes of inflammation and hypertrophy of the nasopharyngeal tonsil and the strategy, tactics and correctness of their treatment deserve scientific attention.
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14

Zaidov, E. Y. "CLINICAL AND EPIDEMIOLOGICAL FEATURES OF ENT PATHOLOGY IN CHILDREN." Клінічна та профілактична медицина 1, no. 19 (February 14, 2022): 28–35. http://dx.doi.org/10.31612/2616-4868.1(19).2022.04.

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Relevance. The insufficiency of studies on the field study of the structure and level of ENT morbidity, which affects the quality and life expectancy of a person in all social and age-sex groups of the population, indicates the relevance of this work. Purpose of the study A retrospective analysis of the indicators of the appealability of pediatric patients with ENT pathology. Material and research methods. In accordance with the set goal and objectives, the study was conducted in the period 2015-2019. An assessment was made of the condition of the ENT organs in children. Results of researches. The obtained data of statistical analysis confirm the high incidence of patients with allergic and catarrhal rhinitis, chronic pharyngitis, sinusitis, inflammatory diseases of the tonsils and adenoid vegetations, etc. Along with the high prevalence of adenoid vegetations, an increase in chronic rhinosinusitis was also observed. On average for 5 years, such diseases of the paranasal sinuses as acute rhinosinusitis 20.7±1.40% and chronic rhinosinusitis 7.8±0.93% prevail. At the same time, the prevalence of injuries to the bones of the nose and nosebleeds decreased during the study period. The data obtained determine the need for timely detection of diseases of the upper respiratory tract in children at the early stages of their development and the organization of measures for systematic dispensary observation. Conclusions. The pathological incidence of ENT diseases in children, being high, nevertheless does not exceed the similar indicators recorded at the final stage of the research. In the structure of ENT pathology of preschool age, the leading place belongs to diseases of the ear. Considering that the lowest prevalence rates of ENT diseases fall on the last year of observation, further reorganization of ENT care for the children's population and periodic preventive medical examinations with the involvement of certain individuals in medical examinations are necessary.
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Plakhtiienko, Inna А., Yevhen V. Smiianov, Vladyslav A. Smiianov, and Volodymyr V. Savchenko. "RESULTS OF THE ULTRAMICROSCOPIC RESEARCH OF ADENOID VEGETATIONS ACCOMPANIED BY THE PATHOLOGIES OF NASAL CAVITY AND PARANASAL SINUSES IN ADULTS." Wiadomości Lekarskie 73, no. 8 (2020): 1626–31. http://dx.doi.org/10.36740/wlek202008107.

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The aim: Grounding on the electronic microscopy of PT make conclusions about the tonsil activity in adults depending on the accompanied pathology of nose and PS. Materials and methods: Ultramicroscopic examination of 111 patients with PT hypertrophy aged 18–55 was done. Depending on the nose and PS pathology (inflammatory, non-inflammatory) patients’ PS biopsic materials were distributed into 2 groups: 58 cases on inflammatory and 53 on non-inflammatory background. The control group consisted of 24 patients aged 18 without nose and PS pathology. The images of ultrathin PT sections were received with the help of transmission electronic microscope PEM – 125 with digital camera (SELMI, Sumy). Results: Great variations in PT cell condition, depending on the pathology were distinguished. Features of the adenoiditis in inflammatory and non-inflammatory diseases of nose and PS were proved. Conclusions: 1. PT ultra-microscopy in control group shows great activity of lymphocytes and high energy exchange of cells, with prevailing B-lymphocyte population. 2. The complex of PT ultra structural changes while nose and PS inflammatory diseases shows the activation of immune reaction in competent cells with T-lymphocyte increase in patients older than 25, which witnesses chronic inflammation. 3. In group with nose and PT non-inflammatory diseases, activity of PT B-lymphocytes is unchanged accompanied by the T-lymphocytes growth, which is also characteristic for chronic inflammation
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16

Flis, P. S., N. V. Raschenko, A. O. Melnyk, V. V. Filonenko, and O. I. Kotov. "STUDY OF THE STATE OF ENT-ORGANS IN CHILDREN WITH ANOMALIES AND DEFORMATIONS OF DENTOALVEOLAR APPARATUS AND SPEECH DISORDERS." Ukrainian Dental Almanac, no. 3 (September 4, 2018): 26–32. http://dx.doi.org/10.31718/2409-0255.3.2018.04.

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The relevance of research. When examining patients with dentoalveolar anomalies, children with speech disorders can often be observed. For orthodontists, it is important to diagnose the etiologic component of these disorders, namely, whether they are the cause of diseases of the ENT-organs and whether they are directly related to orthodontic pathology. In order to study the impact of the pathology of the ENT-organs on the formation of speech disorders, clinical and additional examination methods were carried out. In case of respiratory tract narrowing due to the deviated septum, hypertrophic or allergic rhinitis, adenoid vegetations, hypertrophy of the tonsils, speech pathology may be observed. Specified pathologies are subject to treatment before the logopedic and orthodontic correction. According to our clinical study in children of the main group and of the comparison group, the apparent pathology of the nose and oropharynx was not detected. Subjective and objective methods of hearing examination also did not reveal deviations from the norm. For a more detailed study of the condition of the upper respiratory tract, it is advisable to use computer tomography of the skull and magnetic resonance therapy of the head. The purpose of research is to eliminate the influence of otorhinolaryngologic pathologies on the formation of speech disorders. Materials and methods. We examined 124 patients. Patients were divided into two groups: control and comparison. The control group consisted of 82 patients with anomalies and deformations of dentognathic apparatus and speech disorders. The comparison group consisted of 42 patients without orthodontic pathology who applied to otolaryngologists for a diagnostic examination. The examination did not show the expressed pathology of ENT-organs in the presence of speech impairment and 5 children (aged from 6 to 12 years) with ENT pathology and speech impairment were not included in the main comparison groups. To make clinical and additional diagnosis such methods as rhinoscopy, pharyngoscopy, otoscopy were used. Results and discussion. During the rhinoscopy of all the examined patients of control and comparison groups, it was found: the nasal passages were free, the nasal shells were of the usual size, the nasal membrane was in the medial position, pathological contents in the nasal cavity were not detected. During pharyngoscopy, attention was mainly paid to the size of palatine tonsils. Thus, 62 children (50%) had the 1st and 2nd stage of development, 42 (33.87%) - 2nd stage and 20 (16.13%) - II-III degree. Adenoids (nasopharyngeal tonsil) of the 1st and 2nd degree were established in 86 children (69.35%), 28 children (22.58%) - second degree and 10 (8.06%) - II-III degree, but in all children of the main and comparison groups, nasal breathing function was not noted. In 124 subjects (100%), there was no adenoid type of facial skeleton. Conclusion. With the narrowing of the respiratory tract due to a curvature of the nasal septum, hypertrophic or allergic rhinitis, adenoid vegetation, hypertrophy of the palatine tonsils, speech impairments can be observed. The specified pathologies are subject to treatment before the logopedic and orthodontic correction. According to our clinical examination of children of the main group and the groups of comparison, evident pathology of the nose and oropharynx was not detected. Subjective and objective methods of hearing examination also did not reveal deviations from the norm. For a more detailed study of the condition of the upper respiratory tract, it is advisable to use computer tomography of the skull and magnetic resonance therapy of the head.
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MOGENSEN, HANS HENRIK, KAREN-INGER MEISTRUP-LARSEN, LARS P. RYDER, and KLAUS LIND. "MYCOPLASMA PNEUMONIAE - STIMULATION OF LYMPHOCYTES OBTAINED FROM ADENOID VEGETATIONS AND BLOOD IN CHILDREN WITH AND WITHOUT SEROLOGICAL EVIDENCE OF MYCOPLASMA PNEUMONIAE INFECTION." Acta Pathologica Microbiologica Scandinavica Series C: Immunology 92C, no. 1-6 (August 15, 2009): 313–17. http://dx.doi.org/10.1111/j.1699-0463.1984.tb00093.x.

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MOGENSEN, HANS HENRIK, KAREN-INGER MEISTRUP-LARSEN, UGGI MEISTRUP-LARSEN, and VAGN ANDERSEN. "THE IN VITRO RESPONSE OF LYMPHOCYTES FROM ADENOID VEGETATIONS AND TONSILS TO PPD. INFLUENCE OF AUTOLOGOUS BLOOD MONOCYTES, T LYMPHOCYTES AND UNSEPARATED LYMPHOCYTES." Acta Pathologica Microbiologica Scandinavica Section C Immunology 88C, no. 1-6 (August 15, 2009): 23–30. http://dx.doi.org/10.1111/j.1699-0463.1980.tb00068.x.

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19

Wang, Hai. "Chronic adenoiditis." Journal of International Medical Research 48, no. 11 (November 2020): 030006052097145. http://dx.doi.org/10.1177/0300060520971458.

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In addition to acute adenoiditis and adenoid hypertrophy/vegetation, chronic adenoiditis is another disease of the adenoids. However, most physicians overlook chronic adenoiditis or confuse it with adenoid hypertrophy/vegetation. The incidence of chronic adenoiditis has increased in recent years as a result of higher rates of chronic nasopharyngeal or upper airway infections. The clinical characteristics of chronic adenoiditis can include but are not restricted to the following: long-term infection (especially bacterial infection); obstruction of the upper airway; infections of adjacent regions, such as the nose, nasal sinus, pharyngeal space, middle ear, and atlantoaxial joint; induced upper airway cough syndrome; and the presence of several “infectious-immune” diseases, including rheumatic fever, autoimmune nephropathy, and anaphylactoid purpura. To date, no consensus on the treatment of chronic adenoiditis is available. However, adenoidectomy can address the local obstruction, and some patients benefit from systemic or local anti-bacterial therapy. Physicians in the Departments of Otolaryngology, Respiration, and Pediatrics should be familiar with the clinical manifestations of chronic adenoiditis and try to develop effective treatment methods for this disease.
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Kosakivska, I. A. "«Atypical» adenotomy in children." HEALTH OF WOMAN, no. 2(148) (March 30, 2020): 65–69. http://dx.doi.org/10.15574/hw.2020.148.65.

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With the spread of adenoid vegetation into the nasal cavity, their removal and restoration of the respiratory and auditory function in full is significantly difficult. The objective: of the study was to increase the effectiveness of adenotomy in children. Materials and methods. Under our supervision in the clinic were 239 children with adenoid vegetation II-III degree, aged 2 to 15 years. In the main group, there were 175 children, in the comparison group – 64. In 10 (4.2%) patients, lymphoid tissue from the nasopharynx spread through the choana into the nasal cavity. All children were operated on under endotracheal anesthesia with endoscopic control. Atypical adenotomy was performed in 83 (47.4%) patients of the main group and in 30 (46.9%) patients of the comparison group. Results. 239 children with adenoid vegetation were operated on. In all children of the main group, physiological respiration was restored, hearing was restored or improved, and disease recurrence was not observed. In the comparison group, relapse of adenoid vegetation was detected in 4 (6.25%) cases. In 29.3% of cases, an increased density of adenoid vegetation was revealed. In 13.8% of patients, hypertrophy of the tubular and lateral ridges is observed. Blood loss when using high-frequency current decreased 4.7 times. Conclusions. 1. In 29.3% of pediatric patients, an increased density of adenoid vegetation is detected, and in 4.2%, adenoid vegetation spreads to the nasal cavity, which makes it difficult or sometimes impossible to remove Beckman’s adenotome and requires an «atypical» adenotomy. 2. Atypical location of adenoid vegetation, their increased density and the use of traditional tools for adenotomy can cause a relapse of the disease. Key words: adenoid vegetation, «atypical» adenotomy, children.
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Berçin, A. Sami, Ahmet Ural, Ahmet Kutluhan, and Veysel Yurttaş. "Relationship between Sinusitis and Adenoid Size in Pediatric Age Group." Annals of Otology, Rhinology & Laryngology 116, no. 7 (July 2007): 550–53. http://dx.doi.org/10.1177/000348940711600711.

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Objectives: We sought to examine the relationship between adenoid volume and the stage of rhinosinusitis, as well as the relationship between age and adenoid size. Methods: Forty-two children complaining of nasal discharge, whose paranasal sinus computed tomographic scans had been obtained, were involved in the study. The patients with adenoid enlargement underwent adenoidectomy. The volumes of adenoid vegetation were measured in square centimeters, and paranasal sinus computed tomographic scans were classified according to the Lund-Mackay staging system. Results: No statistically significant difference existed between patients whose Lund-Mackay scores were 0 and those with scores greater than 0. There seems to be no correlation between the Lund-Mackay score and the degree of adenoid vegetation. Conclusions: Adenoid vegetation may cause nasal discharge that is not necessarily due to sinusitis. We could not find any supportive data for the statement “The greater the adenoid tissue, the more extensive the sinusitis.”
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Kocyigit, Murat, Safiye Ortekin, Taliye Cakabay, Guven Ozkaya, Selin Bezgin, and Mustafa Adali. "Frequency of Serous Otitis Media in Children without Otolaryngological Symptoms." International Archives of Otorhinolaryngology 21, no. 02 (June 3, 2016): 161–64. http://dx.doi.org/10.1055/s-0036-1584362.

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Introduction Otitis media with effusion is the fluid in the middle ear with no signs or symptoms of acute ear infection. Objective This study aims to research the frequency of serous otitis media in patients referred to the pediatric clinic between 3–16 years of age without any active ear, nose, and throat complaints. Methods This study included 589 children patients (280 boys, 309 girls; mean age: 9.42; range 3–16) who were administered to the pediatric clinic without otolaryngologic complaints. Patients underwent examination with flexible nasopharyngoscopy for adenoid hypertrophy. An otorhinolaryngologist examined all children on both ears using an otoscope and tested with tympanometry. We used tympanometry results to diagnose SOM. Results The study included 589 patients that underwent fiber optic examination of the nasopharynx with an endoscope. Adenoid vegetation was present in 58 patients (9.8%) and was not detected in 531 patients (90.2%). We found serous otitis media in 94 (15.9%) patients. We obtained Type A tympanogram in 47 (81%) of 58 patients with adenoid vegetation, 6 (10.3%) Type B, and 5 (8.6%) Type C. When comparing 58 patients with adenoid vegetation with 538 patients without adenoid vegetation for serous otitis media, the frequency was not statistically significant (p > 0.05). Conclusion We believe that in children without any ear, nose, and throat complaints, it is possible to detect serous otitis media with adenoid vegetation. Thus, pediatric patients should undergo screening at regular intervals.
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Bozkurt, Gulpembe, Senem Kurt Dizdar, Arzu Yasemin Korkut, and Berna Uslu Coskun. "Adenoid Vegetation in Children with Allergic Rhinitis." Turk Otolarengoloji Arsivi/Turkish Archives of Otolaryngology 53, no. 4 (March 23, 2016): 168–72. http://dx.doi.org/10.5152/tao.2015.1359.

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Wilhelm, T., G. Hilger, K. Begall, J. Lautermann, O. Kaschke, P. Mir-Salim, and T. Zahnert. "S1-Leitlinie „Adenoide Vegetationen/Rachenmandelhyperplasie“." HNO 60, no. 8 (August 2012): 746–52. http://dx.doi.org/10.1007/s00106-012-2555-5.

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Ryazanskaya, A. G., and A. S. Yunusov. "Hypertrophy of adenoid vegetation in modern treatment conditions." Vestnik otorinolaringologii 87, no. 1 (2022): 70. http://dx.doi.org/10.17116/otorino20228701170.

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Berçin, Sami, Ahmet Kutluhan, Hüseyin Çetin, and Veysel Yurttas. "Relationship between adenoid vegetation and anatomic variations of paranasal sinuses." Acta Oto-Laryngologica 128, no. 10 (January 2008): 1116–19. http://dx.doi.org/10.1080/00016480701854735.

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Fukuda, Katsunori, Shoji Matsune, Masato Ushikai, Yoko Imamura, and Masaru Ohyama. "A study on the relationship between adenoid vegetation and rhinosinusitis." American Journal of Otolaryngology 10, no. 3 (May 1989): 214–16. http://dx.doi.org/10.1016/0196-0709(89)90066-5.

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Согоян, И. И., and Л. Г. Петрова. "Endoscopic Examination of the Nasopharynx in Children with Recurrent Forms of Otitis Media." Оториноларингология. Восточная Европа, no. 2 (November 5, 2021): 137–43. http://dx.doi.org/10.34883/pi.2021.11.2.043.

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Введение. В последнее время наблюдается рост числа различных форм рецидивирующих отитов у детей. Цель. Oхарактеризовать эндоскопическую картину носоглотки у детей, страдающих различными формами рецидивирующих отитов (экссудативными, острыми катаральными или гнойными), а также у пациентов с гипертрофией глоточной миндалины без отитов в анамнезе. Материалы и методы. В исследование были включены 68 пациентов. Всем пациентам была проведена тимпанометрия и эндоскопия носоглотки. Обследованы дети в возрасте от 3 до 10 лет. Средний возраст пациентов составил 4,5±2,2 года. Результаты. У преобладающего большинства пациентов с рецидивирующими отитами имелись признаки воспаления аденоидных вегетаций и/или обструкции слуховых труб. При тимпанометрии у них регистрировали тимпанограмму типа В, в то время как у пациентов с гипертрофией глоточной миндалины без отитов в большинстве случаев регистрировали нормальную тимпанограмму (типа А). Данное исследование продемонстрировало ведущую роль дисфункции слуховой трубы, развившейся на фоне хронического воспаления глоточной миндалины в этиопатогенезе рецидивирующих отитов. Выводы. Oхарактеризовав эндоскопическую картину носоглотки у детей, страдающих различными формами рецидивирующих отитов, а также у пациентов с гипертрофией глоточной миндалины без отитов в анамнезе и выявив эндоскопические признаки патологического расположения носоглоточной миндалины, а также признаки их хронического воспаления у детей, страдающих отитами, рекомендуем проводить диагностическую эндоскопию полости носа и носоглотки с визуальным контролем функциональных проб каждому пациенту с рецидивирующим отитом для уточнения характера причин дисфункции слуховой трубы и выбора объема необходимого консервативного или оперативного лечения в последующем Introduction. In the last time, there has been the increase of the number of different forms of recurrent otitis media in children. Purpose. To describe the endoscopic picture of the nasopharynx in children with different forms of recurrent otitis media (exudative, acute catarrhal, or purulent) and in patients with hypertrophy of the pharyngeal tonsil without otitis media in medical history. Materials and methods. The study included 68 patients. All patients underwent tympanometry and nasopharyngeal endoscopy. Children aged from 3 to 10 years were examined. The average age of the patients was 4.5±2.2 years. Results. The majority of patients with recurrent otitis media had the signs of inflammation of the adenoid vegetations and/or obstruction of the auditory tubes. Type B tympanogram was recorded in them, while in patients with hypertrophy of the pharyngeal tonsil without otitis, a normal tympanogram (type А) was recorded in most cases. This study demonstrated the leading role of dysfunction of the auditory tube, which developed during chronic nasopharyngitis, in the etiopathogenesis of recurrent otitis media. Conclusions. Having characterized the endoscopic picture of the nasopharynx in children suffering from various forms of recurrent otitis, as well as in patients with hypertrophy of the pharyngeal tonsil without otitis, and having identified the endoscopic signs of the pathological location of the nasopharyngeal tonsil, as well as the signs of their chronic inflammation in children suffering from otitis media, we recommend to conduct diagnostic endoscopy of the nasal cavity and nasopharynx with visual control of functional tests for each patient with recurrent forms of otitis media. It lets to clarify the cause of the dysfunction of the auditory tube, and it is one of the determining factors in the choice of the amount of necessary conservative and surgical treatment in the future.
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Wilhelm, T., G. Hilger, K. Begall, J. Lautermann, O. Kaschke, P. Mir-Salim, and T. Zahnert. "Erratum zu: S1-Leitlinie „Adenoide Vegetationen/Rachenmandelhyperplasie“." HNO 60, no. 10 (October 2012): 906–7. http://dx.doi.org/10.1007/s00106-012-2589-8.

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Hošnová, Dagmar, and Milan Urík. "Adenoid vegetation from the point of view of an ENT specialist and phoniatrist." Listy klinické logopedie 4, no. 1 (July 14, 2020): 27–30. http://dx.doi.org/10.36833/lkl.2020.013.

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Friese, K. H., U. Feuchter, and H. Moeller. "Die hom�opathische Behandlung von adenoiden Vegetationen." HNO 45, no. 8 (August 25, 1997): 618–24. http://dx.doi.org/10.1007/s001060050136.

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WIESENER, I. "De adenoide vegetationer i cavum nasopharyngeale og betändelsesprocesser i dem." Nordiskt Medicinskt Arkiv 13, no. 4 (April 24, 2009): 1–32. http://dx.doi.org/10.1111/j.0954-6820.1881.tb01261.x.

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Borisov, Konstantin. "Protracted otitis media with effusion in an adult patient with adenoid vegetation. Clinical case presentation." International Bulletin of Otorhinolaryngology 17, no. 3 (September 30, 2021): 15. http://dx.doi.org/10.14748/orl.v17i3.8264.

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Friese, K. H. "Qualitätssicherung in der Homöopathie am Beispiel der adenoiden Vegetationen." Allgemeine Homöopathische Zeitung 242, no. 02 (April 4, 2007): 68–72. http://dx.doi.org/10.1055/s-2006-936597.

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Lim, Eun Jung, Young Kwon Jung, Kyung Rak Sohn, and Tae Hoon Kim. "A Case of Nasopharyngeal Hodgkin Lymphoma Misdiagnosed as Adenoid Vegetation in a 10-Year-Old Boy." Journal of Clinical Otolaryngology Head and Neck Surgery 28, no. 2 (December 2017): 267–72. http://dx.doi.org/10.35420/jcohns.2017.28.2.267.

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Dinc, Mehmet Emre, Aytug Altundag, Denizhan Dizdar, Mehmet Ozgur Avincsal, Ethem Sahin, Seckin Ulusoy, and Ceki Paltura. "An objective assessment of halitosis in children with adenoid vegetation during pre- and post-operative period." International Journal of Pediatric Otorhinolaryngology 88 (September 2016): 47–51. http://dx.doi.org/10.1016/j.ijporl.2016.06.042.

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Torun, Mumtaz. "Neutrophil-to-lymphocyte and basophil-to-lymphocyte ratios in children with adenoid vegetation: Can they be prognostic markers?" Annals of Medical Research 27, no. 6 (2020): 1844. http://dx.doi.org/10.5455/annalsmedres.2020.04.376.

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Dinc, Mehmet Emre, Aytug Altundag, Denizhan Dizdar, Mehmet Ozgur Avincsal, Ethem Sahin, Seckin Ulusoy, and Ceki Paltura. "Response to comment: An objective assessment of halitosis in children with adenoid vegetation during the pre- and postoperative periods." International Journal of Pediatric Otorhinolaryngology 98 (July 2017): 172–73. http://dx.doi.org/10.1016/j.ijporl.2016.12.012.

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Bugova, Gabriela, Barbora Uhliarova, Milos Jesenak, and Andrej Hajtman. "The presence of atopy and its effect on bacterial colonization of the upper airways in children with adenoid vegetation." Alergologia Polska - Polish Journal of Allergology 4, no. 2 (April 2017): 46–52. http://dx.doi.org/10.1016/j.alergo.2017.04.002.

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Min, Hyun Jin, and Kyung Soo Kim. "Letter to the Editor regarding ‘‘An objective assessment of halitosis in children with adenoid vegetation during pre- and post-operative period’’." International Journal of Pediatric Otorhinolaryngology 98 (July 2017): 171. http://dx.doi.org/10.1016/j.ijporl.2016.12.014.

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Martinez, Carlos Augusto Real, Júlia Cutovoi, Debora Helena Rossi, Luciana Rodrigues Meirelles, Maria de Lourdes Setsuko Ayrizono, Raquel Franco Leal, and Cláudio Saddy Rodrigues Coy. "Intramucosal Carcinoma of the Appendix Arising from Traditional Serrated Adenoma." Case Reports in Surgery 2015 (2015): 1–6. http://dx.doi.org/10.1155/2015/297450.

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Introduction. Serrated adenomas of the appendix are rare and usually found during appendectomy or autopsies. The preoperative diagnosis of these tumors is uncommon. This report describes a case of a sessile serrated adenoma located in the appendix diagnosed by a screening colonoscopy and successfully treated by laparoscopic removal.Presentation of Case. An 86-year-old woman underwent colonoscopy to investigate the cause of her diarrhea, weight loss, and anemia. During the colonoscopy, an expansive and vegetating mass of 1.5 cm in diameter was identified, protruding through the appendicular ostium with slightly lateral growth to the cecum. The patient was referred for laparoscopic surgical resection due to the location of the lesion, which did not allow its removal by colonoscopy. She underwent wedge removal of the cecum without complications and was discharged on the 4th postoperative day. Histopathological examination showed the presence of a sessile serrated adenoma with an intramucosal adenocarcinoma. The patient is currently well one year after surgery, without endoscopic signs of relapse.Conclusion. Despite serrated adenomas being a possibility rarely described in appendix it should be recognized and properly treated because it is presenting a higher risk of cancer.
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Попович, В. И., and Г. В. Бекетова. "Mythical Diagnoses in Pediatrics: Adenoiditis or Nasopharyngitis? Which diagnosis is correct? Questions and Answers." Педиатрия. Восточная Европа, no. 2 (June 17, 2021): 294–303. http://dx.doi.org/10.34883/pi.2021.9.2.013.

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В педиатрии существует много так называемых мифических диагнозов, среди которых и «аденоидит», который часто используется врачами первого контакта. В статье в форме вопросов и ответов представлена мультидисциплинарная дискуссия, касающаяся анатомо-физиологических подходов в формировании диагноза «острый риносинусит» и «острый назофарингит». Авторы обсуждают врачебные ошибки в отношении синдрома насморка у детей, неправомерности диагноза «аденоидит», понятия «аденоидные вегетации», физиологической роли лимфоидной ткани в носоглотке. Представлены клинические критерии острого риносинусита и острого назофарингита, их этиология и патогенетическая сущность. Рассмотрены современные подходы к лечению поражений носа, околоназальных пазух и носоглотки с использованием стандартизованных фитониринговых препаратов Синупрет и Имупрет. In pediatrics, there are many so-called mythical diagnoses, including “adenoiditis”, which is often used by doctors of the first contact. The article in the form of “questions and answers” presents a multidisciplinary discussion concerning the anatomical and physiological approaches in the formation of the diagnoses “acute rhinosinusitis” and “acute nasopharyngitis.” The authors discuss medical errors in relation to the rhinitis syndrome in children, inappropriateness of the diagnosis of “adenoiditis”, the concept of “adenoid vegetation”, physiological role of lymphoid tissue in the nasopharynx. The clinical criteria for acute rhinosinusitis and acute nasopharyngitis, their etiology and pathogenetic essence are presented. Modern approaches to the treatment of lesions of the nose, paranasal sinuses, and nasopharynx using the standardized phytoneering drugs Sinupret and Imupret are considered.
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Chand, Gaurav, Leonid Shamban, Adam Forman, and Prabhat Sinha. "The Association ofStreptococcus gallolyticusSubspeciespasteurianusBacteremia with the Detection of Premalignant and Malignant Colonic Lesions." Case Reports in Gastrointestinal Medicine 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/7815843.

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Streptococcus gallolyticussubspecies (subsp.)gallolyticus(formerlybovisbiotype I) bacteremia has been associated with colonic adenocarcinoma. Thebovisspecies underwent reclassification in 2003. Subtypes ofgallolyticusare associated with colonic malignancy but are less frequent, resulting in less awareness. A 71-year-old male admitted with worsening lower back pain and fevers. Initial vital signs and laboratory data were within normal limits. MRI revealed lumbosacral osteomyelitis and antibiotics were initiated. Blood cultures showedStreptococcusspecies, prompting a transesophageal echocardiogram (TEE) revealing vegetations on the mitral and aortic valves. The etiology for his endocarditis was unclear. A colonoscopy was suggested, but his clinical instability made such a procedure intolerable. Final cultures revealedStreptococcus gallolyticussubsp.pasteurianus(previouslybovisbiotype II). After antibiotic completion he underwent aortic grafting with valve replacements. Later, he was readmitted forStreptococcusbacteremia. After a negative TEE, colonoscopy revealed a 2.5 × 3 cm cecal tubulovillous adenoma with high-grade dysplasia suspicious for his origin of infection. Clinicians understand the link betweenStreptococcus gallolyticussubsp.gallolyticus(bovistype I) and malignancy, but the new speciation may be unfamiliar. There are no guidelines for managingS. gallolyticussubsp.pasteurianusbacteremia; therefore a colonoscopy should be considered when no source is identified.
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da Costa, Joana Borges, Ana Isabel Goncalves, Andre Carcao, Joana Santos, Delfim Duarte, and Miguel Viana. "Carcinoma Ex Pleomorphic Adenoma of the Uvula - Case Report." Journal of Biomedical Research & Environmental Sciences 2, no. 7 (July 31, 2021): 543–47. http://dx.doi.org/10.37871/jbres1274.

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Introduction: Carcinoma Ex Pleomorphic Adenoma (CEPA) results from the malignant transformation of a benign tumor of the Salivary Glands (SG), the Pleomorphic Adenoma (PA). PA is considered the most common salivary tumor with a 5% risk of malignant transformation and its excision is recommended. CEPA is a rare tumor, corresponding to 3.6% of all salivary tumors and 11.6% of all GS carcinomas. About 18% of CEPAs affect minor SG, with the palate being the most common location. The present work serves to describe a case of a CEPA of the Uvula Minor SG (UMSG). Case Report: We present a case report of a 57-year-old patient, with no relevant medical history, referred to the ENT consultation due to the appearance and progressive growth of a painless uvula lesion. The objective ENT examination showed a 15 mm ulcerative-vegetating lesion with apparent origin on the posterior face of the uvula. The lesion was biopsied and histopathological examination identified the presence of a neoplasm of the minor SG, probably NOS adenocarcinoma. The patient underwent Computed Tomography (CT) scan that showed an irregularity of the uvula, with no signs of invasion of the remaining soft palate, without other significant pharyngo-laryngeal changes. The patient underwent partial pharyngectomy and bilateral selective cervical ganglion dissection, and the histopathology of the surgical specimen confirmed that it was an invasive CEPA, the malignant component of the tumor corresponding to a NOS adenocarcinoma of the UMSG. The patient has been followed up in the ENT consultation, with no signs so far of loco-regional recurrence. Discussion/Conclusion: In the presented case, the patient probably developed an undiagnosed PA that had become malignant over time. Given that it is a poor prognosis neoplasm, it’s essential that the ENT specialists are aware of this disease, in order to facilitate and anticipate the diagnosis and treatment as much as possible.
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Ursaru, Andreea Maria, Cristian Mihai Haba, Ștefan Eduard Popescu, Daniela Crișu, Antoniu Octavian Petriș, and Nicolae Dan Tesloianu. "A Rare Entity–Percutaneous Lead Extraction in a Very Late Onset Pacemaker Endocarditis: Case Report and Review of Literature." Diagnostics 11, no. 1 (January 9, 2021): 96. http://dx.doi.org/10.3390/diagnostics11010096.

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The number of infections related to cardiac implantable electronic devices (CIEDs) has increased as the number of devices implanted around the world has grown exponentially in recent years. CIED complications can sometimes be difficult to diagnose and manage, as in the case of lead-related infective endocarditis. We present the case of a 48-year-old male diagnosed with Staphylococcus aureus device-related infective endocarditis, 12 years after the implant of a single chamber pacemaker. A recent history of the patient includes two urinary catheterizations due to obstructive uropathy in the context of a prostatic adenoma, 2 months previously, both without antibiotic prophylaxis; no other possible entry sites were found and no history of other invasive procedures. After initiation of antibiotic therapy according to antibiotic susceptibility testing, we decided to remove the right ventricular passive fixation lead along with the vegetation and pacemaker generator; because of severe lead adhesions in the costoclavicular region, and especially in the right ventricle, we needed mechanical sheaths to remove the abundant fibrous tissue that encompassed the lead. After a difficult, but successful, lead extraction along with a large vegetation and 6 weeks’ antibiotic therapy, the clinical and biological evolution was favorable, without reappearance of symptoms. While very late lead endocarditis is a rarity, late lead-related infective endocarditis (more than 12 months elapsed since implant) is not an exception; this is why we find that endocarditis prophylaxis should be reconsidered in certain patient categories, our patient being proof that procedures with neglectable endocarditis risk according to the guidelines can lead to bacterial endocarditis.
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46

Ursaru, Andreea Maria, Cristian Mihai Haba, Ștefan Eduard Popescu, Daniela Crișu, Antoniu Octavian Petriș, and Nicolae Dan Tesloianu. "A Rare Entity–Percutaneous Lead Extraction in a Very Late Onset Pacemaker Endocarditis: Case Report and Review of Literature." Diagnostics 11, no. 1 (January 9, 2021): 96. http://dx.doi.org/10.3390/diagnostics11010096.

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The number of infections related to cardiac implantable electronic devices (CIEDs) has increased as the number of devices implanted around the world has grown exponentially in recent years. CIED complications can sometimes be difficult to diagnose and manage, as in the case of lead-related infective endocarditis. We present the case of a 48-year-old male diagnosed with Staphylococcus aureus device-related infective endocarditis, 12 years after the implant of a single chamber pacemaker. A recent history of the patient includes two urinary catheterizations due to obstructive uropathy in the context of a prostatic adenoma, 2 months previously, both without antibiotic prophylaxis; no other possible entry sites were found and no history of other invasive procedures. After initiation of antibiotic therapy according to antibiotic susceptibility testing, we decided to remove the right ventricular passive fixation lead along with the vegetation and pacemaker generator; because of severe lead adhesions in the costoclavicular region, and especially in the right ventricle, we needed mechanical sheaths to remove the abundant fibrous tissue that encompassed the lead. After a difficult, but successful, lead extraction along with a large vegetation and 6 weeks’ antibiotic therapy, the clinical and biological evolution was favorable, without reappearance of symptoms. While very late lead endocarditis is a rarity, late lead-related infective endocarditis (more than 12 months elapsed since implant) is not an exception; this is why we find that endocarditis prophylaxis should be reconsidered in certain patient categories, our patient being proof that procedures with neglectable endocarditis risk according to the guidelines can lead to bacterial endocarditis.
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47

Mashkova, T. A., I. I. Chirkova, O. N. Yamshchikov, I. Yu Revyakin, V. A. Ershova, and A. A. Pudovkin. "Endogenous intoxication in chronic pathology of pharynx in children." Russian Otorhinolaryngology 20, no. 3 (2021): 94–101. http://dx.doi.org/10.18692/1810-4800-2021-3-94-101.

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A review of scientific Russian and foreign articles devoted to the development of endogenous intoxication in chronic inflammatory pathology of the lymphoepithelial pharyngeal ring is carried out. Chronic tonsillitis and adenoiditis in children are one of the unsolved issues in otorhinolaryngology. Chronic tonsillitis is a chronic inflammation of the palatine tonsils characterized by recurrent exacerbations in the form of tonsillitis and a general toxic-allergic reaction. Adenoid vegetation is a pathological hypertrophy of the pharyngeal tonsil. Chronic adenoiditis is a chronic polyetiologic disease, which is based on a violation of the physiological immune processes of the pharyngeal tonsil. In children, one cannot talk about an isolated inflammation of the pharyngeal tonsil, since as a result of exposure to antigens, an immune response arises, which involves all structures of the lymphoepithelial pharyngeal ring in the process, therefore some authors distinguish the term «adenotonsillitis». With pronounced activation of microflora in the nasopharynx and oropharynx, the body’s resistance to pathogenic microorganisms decreases, as a result of which decay products and toxins damage the vascular endothelium, disrupt their permeability and, penetrating through the epithelial barrier, contribute to the development of chronic intoxication and sensitization of the body. Endogenous intoxication is a polyetiologic and polypathogenetic syndrome characterized by the accumulation of endogenous toxins in tissues and biological fluids. Diagnostics of the endogenous intoxication severity includes a number of clinical and laboratory indicators and immunological markers. But, despite the constant improvement of the research methods, the issue of endotoxicosis diagnosis in chronic tonsillitis and adenoiditis remains insufficiently studied. As a result of the inadequate diagnosis, there is often a simultaneous removal of the pharyngeal and palatine tonsils, which in turn can lead to irreversible consequences.
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Urík, Milan, Michal Bartoš, Soňa Šikolová, Jana Jančíková, Klára Perceová, Jiří Jarkovský, Eva Klabusayová, Petr Štourač, and Petr Jabandžiev. "Risk Factors for Postoperative Bleeding after Adenoidectomy." Children 8, no. 3 (March 21, 2021): 242. http://dx.doi.org/10.3390/children8030242.

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IMPORTANCE: Postoperative bleeding is a common and potentially life-threatening complication. Precise identification of risk factors in addition to the basic ones, such as coagulation parameters, is certainly very desirable. OBJECTIVE: The aim of this study was to identify other possible risk factors for bleeding after adenoidectomy in children. DESIGN: This observational prospective study enrolled children undergoing adenoidectomy from October 2019 to February 2020, then evaluated the influence of possible risk factors for bleeding. SETTING: Tertiary pediatric otorhinolaryngology center. PARTICIPANTS: A total of 288 children aged 0–18 years undergoing adenoidectomy for recurrent upper respiratory tract infections, recurrent acute otitis media, secretory otitis media, and obstructive sleep apnea syndrome. MAIN OUTCOMES AND MEASURES: Increased blood pressure and time of surgery were identified as risk factors for bleeding after adenoidectomy. RESULTS: Elevated systolic (p = 0.046), diastolic (p = 0.012), and mean arterial blood pressure (p = 0.007) (Mann–Whitney U test) as adjusted for age-specific distributions and with corrections for height and weight, as well as time length of surgery (p < 0.001) (Fisher’s exact test) were revealed as statistically significant risk factors for postoperative bleeding. Atmospheric pressure, surgeon’s level of experiences, chronic inflammatory content in adenoid vegetation (AV), size of AV, recidivism of AV, recurrent infections of the upper respiratory tract, type of anesthesia, long-term using of drugs, and positive coagulation questionnaire or pathology in standard coagulation tests were not found to be risk factors for bleeding after adenoidectomy. CONCLUSIONS AND RELEVANCE: In this prospective study within a well-defined population of children, we evaluated increased blood pressure and time of surgery as risk factors for bleeding after adenoidectomy. These data bring new information that complements current knowledge in this field.
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"Homoeopathy little better than placebo in adenoid vegetations." Focus on Alternative and Complementary Therapies 3, no. 1 (June 14, 2010): 16–17. http://dx.doi.org/10.1211/fact.1998.00015.

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Dmitrova, Evgeniia, Oleksandr Smiyan, Viktoria Holubnycha, Kateryna Smiian, Tatiana Bynda, Yurii Reznychenko, Ihor Vysotsky, et al. "STATE OF IMMUNITY IN PRESCHOOLERS WITH ACUTE RESPIRATORY VIRAL INFECTIONS ASSOCIATED WITH ADENOID VEGETATIONS." Proceedings of the Shevchenko Scientific Society. Medical Sciences 65, no. 2 (December 29, 2021). http://dx.doi.org/10.25040/ntsh2021.02.17.

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Introduction. Acute respiratory infections are the most common infectious diseases worldwide among children of different age groups. Materials and methods. 59 children between the ages of 3 and 7 participated in the study. The first group included 22 patients with an acute respiratory viral infection, the second one consisted of 23 patients with acute respiratory viral infections associated with adenoid vegetation, and 14 apparently healthy children were included in the control group. Immunology research was conducted during the acute period of the disease. Statistical processing of received data was done with the standard statistical software EZR 1.41. Results. After the research, most of the patients with acute respiratory viral infections were identified an actual increase in CD3+, CD4+, CD8+, CD22+- cells and IgA, IgM in the blood serum. Simultaneously, in patients with acute respiratory viral infections associated with adenoid vegetation during the acute period, the increase in total lymphocytes was identified due to CD4+, CD8+, CD22+ cells and IgG. A comparative analysis of the study results of both groups of patients showed that children from the second group had a significantly higher level of CD3+- cells, while the CD22+- lymphocytes, IgA, IgM and IgG were significantly lower from the similar indicators of the first group. Conclusions. The acute period of the disease in children with acute respiratory viral infections, associated with adenoid vegetation, had an imbalance in both the cell and the immune system's humoral component
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