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1

Behera, Biswanath, Rashmi Kumari, Debasis Gochhait, Arjuna Babu Sathya, and Devinder Mohan Thappa. "Dermoscopy of adenoma sebaceum." Journal of the American Academy of Dermatology 76, no. 2 (2017): S86—S88. http://dx.doi.org/10.1016/j.jaad.2016.05.023.

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2

Swaroop, MR, KC Nischal, CM Rajesh Gowda, NU Umashankar, HB Basavaraj, and BD Sathyanarayana. "Radiofrequency ablation of adenoma sebaceum." Journal of Cutaneous and Aesthetic Surgery 1, no. 2 (2008): 89. http://dx.doi.org/10.4103/0974-2077.44166.

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3

BUNDEY, SARAH, G. DUTTON, and R. S. WELLS. "TUBEROSE SCLEROSIS WITHOUT ADENOMA SEBACEUM." Journal of Intellectual Disability Research 14, no. 3 (2008): 243–49. http://dx.doi.org/10.1111/j.1365-2788.1970.tb01120.x.

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4

Babu, Ch Madhu, Padmaja P, Raghu Kiran B, and Yaswanth T. "ROLE OF RADIOFREQUENCY ABLATION IN ADENOMA SEBACEUM." Journal of Evidence Based Medicine and Healthcare 3, no. 30 (2016): 1368–69. http://dx.doi.org/10.18410/jebmh/2016/312.

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5

Naeem, Ume Hani, Mohammad Noor, and Fawad Rahim. "Tuberous Sclerosis Complex." Khyber Journal of Medical Sciences 14, no. 1 (2021): 59–62. https://doi.org/10.70520/kjms.v14i1.255.

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Tuberous Sclerosis Complex (TSC) is a rare, autosomal dominant, neurocutaneous disease characterized by the development of benign tumors that affect the brain, skin, retina, and other viscera. The clinical presentation is variable between and within families with respect to the number and severity of clinical manifestations. Nearly all patients have one or more dermatological manifestations, the most common being adenoma sebaceum, and most patients have epilepsy. The classic triad of facial adenoma sebaceum, epilepsy, and cognitive deficit (Vogt triad) is present only in one-third of the patie
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6

Khanna, Rakesh, and Milind Borde. "Mania in a Five-Year-Old Child with Tuberous Sclerosis." British Journal of Psychiatry 155, no. 1 (1989): 117–19. http://dx.doi.org/10.1192/bjp.155.1.117.

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A five-year-old girl presented with mania and adenoma sebaceum. Later she developed grand mal seizures, and EEG revealed a prominent right temporal focus. It is important to consider tuberous sclerosis as aetiologically related to mood disorders.
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7

Krishnan, Prasad, and SachinkumarMaheshbhai Patel. "Adenoma sebaceum: Dermatological finding unmasking central nervous system pathology." Journal of Pediatric Neurosciences 11, no. 4 (2016): 378. http://dx.doi.org/10.4103/1817-1745.199465.

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8

Park, Yoon-Kee, and Seung Kyung Hann. "Cluster growths in adenoma sebaceum associated with tuberous sclerosis." Journal of the American Academy of Dermatology 20, no. 5 (1989): 918–20. http://dx.doi.org/10.1016/s0190-9622(89)70108-0.

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9

Sakuma, T., C. Ueno, and K. Kawano. "Adenoma Sebaceum der Caruncula Lacrimalis: Bericht über zwei Fälle." Klinische Monatsblätter für Augenheilkunde 226, no. 05 (2009): 432–33. http://dx.doi.org/10.1055/s-0028-1109159.

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10

WHEELAND, RONALD G., PHILIP L. BAILIN, GARY R. KANTOR, NEIL P. J. WALKER, and JOHN L. RATZ. "Treatment of Adenoma Sebaceum with Carbon Dioxide Laser Vaporization." Journal of Dermatologic Surgery and Oncology 11, no. 9 (1985): 861–64. http://dx.doi.org/10.1111/j.1524-4725.1985.tb03555.x.

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11

Kaufman, Andrew J., Roy C. Grekin, John K. Geisse, and Ilona J. Frieden. "Treatment of adenoma sebaceum with the copper vapor laser." Journal of the American Academy of Dermatology 33, no. 5 (1995): 770–74. http://dx.doi.org/10.1016/0190-9622(95)91814-0.

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12

F.N, Raghavendra, Ramu Ramu, Sagar C. Hiremath, Jeffrey Joy Panicker, Arpitha S.V, and P. Thulasinadh. "CASE REPORT OF TUBEROUS SCLEROSIS IN PATIENT PRESENTED WITH VASAMOL CONSUMPTION." International Journal of Advanced Research 13, no. 06 (2025): 491–95. https://doi.org/10.21474/ijar01/21109.

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Tuberous sclerosis complex (TSC) is a rare genetic neurocutaneous syndrome characterized by glial tumors in the brain and retina, fibromas in various organs, and a classic triad of epilepsy, intellectual disability, and adenoma sebaceum. However, nearly 50% of affected individuals have normal intelligence, and 15% do not experience seizures. Neurological symptoms typically appear in childhood, while skin manifestations often emerge later. We present the case of a 31 year-old woman diagnosed with TSC, who initially sought medical attention for vasamol consumption. The patient developed rhabdomy
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13

Bhatkar, Sanat, and Aastha Takkar. "Focal gigantism in tuberous sclerosis." International Journal of Epilepsy 04, no. 01 (2017): 104–5. http://dx.doi.org/10.1016/j.ijep.2017.02.001.

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AbstractA 38 year lady had recurrent generalized and myoclonic seizures since 6 years of age. On examination she had facial adenoma sebaceum and periungal fibromas, cutaneous angiofibromas on the back. Contrast enhanced magnetic Resonance Imaging of brain was suggestive of multiple cortical tubers with sub ependymal nodules consistent with the diagnosis of Tuberous sclerosis. Focal hypertrophy of the skin of the dorsal aspect of the left hand with focal gigantism was noted.
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14

Ramesh, Kanumury, and Paruchuri Naga Manvi. "A case of Giant Renal Angiomyolipoma in Tuberous Sclerosis Complex." International Surgery Journal 5, no. 10 (2018): 3422. http://dx.doi.org/10.18203/2349-2902.isj20184102.

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ABSTRACT:Angiomyolipomas also referred to as renal hamartoma is a benign lesion.They are either sporadic or associated with syndromes like tuberous sclerosis. Here we present a case of 58yrs old male patient, who presented with left sided abdominal pain for 1month.On examination over face Adenoma Sebaceum was present.Ultrasound abdomen and contrast enhanced computed tomography showed bilateral renal angiomyolipoma with aneurysm over left side.On plain computed tomography of head subependymal calcifications were present.Left Nephrectomy was done and histopathology revealed Angiomyolipoma.
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15

FINCH, HINDSON, and COTTERILL. "Successful treatment of adenoma sebaceum with the potassium titanyl phosphate laser." Clinical and Experimental Dermatology 23, no. 5 (1998): 201–3. http://dx.doi.org/10.1046/j.1365-2230.1998.00371.x.

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16

Weston, Jane, David B. Apfelberg, Morton R. Maser, Harvey Lash, and David White. "Carbon Dioxide Laserbrasion for Treatment of Adenoma Sebaceum in Tuberous Sclerosis." Annals of Plastic Surgery 15, no. 2 (1985): 132–37. http://dx.doi.org/10.1097/00000637-198508000-00007.

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17

Bundey, Sarah, G. Button, and R. S. Wells. "A NOTE ON A CASE OF “TUBEROSE SCLEROSIS WITHOUT ADENOMA SEBACEUM”." Journal of Intellectual Disability Research 16, no. 1-2 (2008): 67. http://dx.doi.org/10.1111/j.1365-2788.1972.tb01573.x.

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18

El-Musa, Kusai A., Ramzi S. Shehadi, and Sameer Shehadi. "Extensive facial adenoma sebaceum: successful treatment with mechanical dermabrasion: case report." British Journal of Plastic Surgery 58, no. 8 (2005): 1143–47. http://dx.doi.org/10.1016/j.bjps.2005.04.021.

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19

Grohmann, Martin, Stefan Benedikt, Abigail Forbes, and Ivo Justich. "Ablation of facial adenoma sebaceum using the Versajet™ Hydrosurgery System." European Journal of Plastic Surgery 41, no. 1 (2017): 93–96. http://dx.doi.org/10.1007/s00238-017-1347-2.

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20

Mostafa, Khan Golam, Choudhury Habibur Rasul, Nitya Nanda Baruri, and Razia Sultana. "Tuberous sclerosis misdiagnosed as epilepsy." Bangladesh Medical Journal Khulna 46, no. 1-2 (2014): 31–33. http://dx.doi.org/10.3329/bmjk.v46i1-2.18238.

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Tuberous sclerosis (TS) is a rare genodermatoses characterized by neurological symptoms and hamartomas in multiple organs including brain, skin, kidney, eyes, heart, lungs & G.I tract. The classic triad of epilepsy, adenoma sebaceum and mental retardation usually occurs in one third of the patients, thus requiring high index of suspicion to diagnose TS. Otherwise it may easily be misdiagnosed as epilepsy or neurofibromatosis. Here we present a case of tuberous sclerosis in 11 year old girl misdiagnosed as epilepsy because of her convulsions. A comprehensive medical history including family
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21

SHINDO, Yasuko, Junichi AKIYAMA, and Yoshio TAKASE. "Collagen synthesis in cultured non-epithelial cells derived from adenoma sebaceum in pringle disease." Nishi Nihon Hifuka 49, no. 4 (1987): 683–86. http://dx.doi.org/10.2336/nishinihonhifu.49.683.

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22

Kim, Sanggu, Preeti Kumari Chaudhary, Sachin Upadhayaya, Kwang Won Seo, and Soochong Kim. "Histopathological and Immunohistochemical Characterization of Sebaceous Adenoma and Epithelioma in Dogs." Animals 14, no. 10 (2024): 1457. http://dx.doi.org/10.3390/ani14101457.

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Sebaceous gland tumors are neoplasms originating from the sebaceous gland and are the third most common type of skin tumor, accounting for 21–35% of all cutaneous neoplasms in dogs. According to their histopathological characteristics, sebaceous gland tumors can be classified into adenoma as a benign tumor and epithelioma as a malignant tumor. Sebaceous epithelioma is distinguished from sebaceous adenoma by containing 90% or more reserve cells. However, this simple numerical criterion is insufficient to histologically distinguish between epitheliomas and adenomas. In addition, sebaceoma in hum
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23

Dowerah, Swagata, and Munmun Harlalka. "A histopathological study of sebaceous neoplasms and related lesions at a tertiary care centre." International Journal of Research in Medical Sciences 7, no. 5 (2019): 1894. http://dx.doi.org/10.18203/2320-6012.ijrms20191696.

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Background: Sebaceous lesions have intrigued pathologists and dermatologist alike causing a great deal of diagnostic confusion. Tumors and tumor like conditions of the sebaceous glands include sebaceous hyperplasia, Nevus sebaceus of Jadassohn, sebaceous adenoma, sebaceoma and sebaceous carcinoma.Methods: A three-year study of all lesions with sebaceous differentiation was carried out in the histopathology section of a tertiary care hospital to study the spectrum of lesions showing sebaceous differentiation. Patient records were noted, and paraffin embedded sections stained with haematoxylin a
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24

Bhatt, Ruchita. "Retinal Hamartomas in a case of Tuberous Sclerosis." VIMS Health Science Journal 8, no. 1 (2021): 43–46. http://dx.doi.org/10.46858/vimshsj.8109.

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A 21 year old male patient suffering from epilepsy came for fundoscopic evaluation. Right eye showed a flat, smooth surfaced well circumscribed, non-calcified translucent lesion of 1 disc dioptre size, inferior to the optic disc, obscuring underlying vessels & an opaque, calcified,yellow white lesion having irregular surface & margins with mulberry appearance, elevated, supero-nasal to the disc, obscuring the underlying vessels. Adenoma sebaceum, periungual fibromas, Ash leaf macules were seen on general physical examination suggestive of tuberous sclerosis. MRI brain revealed subepend
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25

Ali, M., Zeba Un-Naher, GM Faruk Hossain, Zahida Zabber, and Shafiqul Islam. "Tuberous Sclerosis - A Case Report." Journal of Science Foundation 9, no. 1-2 (2013): 59–63. http://dx.doi.org/10.3329/jsf.v9i1-2.14648.

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The aim of this case report was to present a typical case of tuberous sclerosis. On 28 April 2012 a 8 year old female student reported as out patient of Ophthalmology Department, BSMMU, Dhaka. After taking history from the patient, ocular and systemic examinations were done. This patient had recurrent attacks of convulsion since 2 months of age and blurring of vision for 3 months. Ocular examination revealed fundus astrocytomas and patchy iris hypo-pigmentation. Systemic examination present with adenoma sebaceum. For diagnosis purpose, she was advised for investigation. CT scan of brain-Multip
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26

Verma Saluja, Komal, Priyanka Sangar, Drishya Pillai, and Chetan Prakash Suman. "Tuberous sclerosis complex: one disorder, three generations and an assortment of radiological and clinical presentations." BMJ Case Reports 18, no. 1 (2025): e261774. https://doi.org/10.1136/bcr-2024-261774.

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This case report presents markedly different clinical and radiological manifestations of the same disease in a family over three consecutive generations with varying treatment strategies. The index case/proband primarily presented with gastrointestinal symptoms, including diarrhoea, bleeding per rectum and seizures. Further evaluation revealed bilateral renal angiomyolipoma and cerebral subependymal nodules, in conjunction with facial adenoma sebaceum, periungual fibromas and hypomelanotic ash-leaf macules. Genetic testing confirmed the diagnosis of tuberous sclerosis complex, identifying a mu
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27

Henkes, H., J. Richter, A. Kretschmer, P. Benz, G. Brill, and W. Dewes. "Tuberöse Sklerose: Erweiterung der Diagnostik durch MR-Tomographie und Computertomographie." Nuklearmedizin 31, no. 05 (1992): 192–98. http://dx.doi.org/10.1055/s-0038-1629622.

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ZusammenfassungEs wird über 10 Kinder und eine 22jährige Erwachsene mit tuberöser Sklerose berichtet. Neben der Erhebung des internistischen und neurologischen Status wurden die Patienten computer- und kernspintomographisch untersucht. Alle 10 Kinder hatten zerebrale Krampfanfälle, nur 8 Hautveränderungen (Adenoma sebaceum, white spots), 4 ein Rhabdomyom des Herzens, 4 Astrozytome der Retina und nur 4 wiesen die vollständige Trias der Erkrankung mit Epilepsie, Hautveränderungen und geistiger/körperlicher Entwicklungsverzögerung auf. Die erwachsene Patientin war an einer Abortivform der tuberös
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28

Dakson, A., and P. McNeely. "P.050 NICO-assisted neuroendoscopic management of enlarging subependymal giant cell astrocytoma in tuberous sclerosis complex: a case report." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 45, s2 (2018): S28. http://dx.doi.org/10.1017/cjn.2018.152.

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Background: Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous syndrome classically associated with mental disability, seizure disorder and adenoma sebaceum, among other anomalies. One of the major causes of mortality and morbidity in adults is the exclusive occurrence of subependymal giant cell astrocytoma (SEGA) which responds in at least 35% of cases to everolimus, mTOR inhibitor. However, drug treatment is associated with 33% rate of adverse events and requires long-term treatment Methods: In this report, we present a case of 49-year old female with TSC and a left enl
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Chabalala, W. T., K. Bojosi, T. Maphane, and A. Olashore. "Neuropsychiatric Manifestations of Tuberous Sclerosis in a young adult male in a Psychiatry Hospital in Botswana: a case report." European Psychiatry 67, S1 (2024): S495—S496. http://dx.doi.org/10.1192/j.eurpsy.2024.1027.

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IntroductionTuberous sclerosis complex (TSC) is a disorder that affects multiple systems and was first described in 1880. Its symptoms include seizures, intellectual disability, and adenoma sebaceum. TSC is caused by mutations in the TSC1 and TSC2 genes and is inherited in an autosomal dominant manner.ObjectivesThis report highlights a case of a patient with an unusual psychological presentation evaluated in a psychiatric hospital.MethodsThe patient presented with psychotic features and abnormal behavior. A physical examination showed neurocutaneous lesions. After assessment a diagnosis of Tub
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30

Barron, Cynthia Reyes, and Bruce R. Smoller. "GLUT1 Expression in Cutaneous Sebaceous Lesions Determined by Immunohistochemical Staining Patterns." Dermatopathology 8, no. 3 (2021): 258–64. http://dx.doi.org/10.3390/dermatopathology8030031.

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GLUT1 is a membrane associated carrier protein that functions in the physiologic transport of glucose across cell membranes. Multiple studies have shown an increased GLUT1 expression in various tumor types and a role in cancer prognosis. The aim of this study was to determine whether cutaneous sebaceous lesions have a differential expression of GLUT1 by immunohistochemistry (IHC). GLUT1 IHC was performed on excision specimens of ten cases of sebaceous carcinoma, nine of sebaceoma, ten of sebaceous adenoma, and ten of sebaceous hyperplasia. Intense, diffuse cytoplasmic staining was observed in
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31

Dincă, Octavian Marius, Mihai Bogdan Bucur, George Cristian Vlădan, Valentin Nicolae Varlas, and Alexandru Bucur. "An Extremely Rare Case of Sebaceous Adenoma Involving the Parotid Gland." Diagnostics 12, no. 5 (2022): 1232. http://dx.doi.org/10.3390/diagnostics12051232.

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Sebaceous adenoma is an extremely rare tumor located in the parotid gland. In the English literature, less than 10 cases have been reported. Sebaceous adenoma represents 0.5% of all monomorphic adenomas. The authors are presenting a case of sebaceous adenoma of the parotid gland in a 65-year-old female who presented a mass on the left parotid area that had been gradually enlarging for one year without symptoms of pain. On imaging (ultrasound), a well-defined mass lesion in the left parotid area was seen. Histopathological findings were consistent with sebaceous adenoma. Surgical excision is cu
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32

Somashekara, K. G., S. Lakshmi, and N. S. Priya. "A rare case of sebaceous adenoma of the palate, with literature review." Journal of Laryngology & Otology 125, no. 7 (2011): 750–52. http://dx.doi.org/10.1017/s0022215111000582.

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AbstractObjective:We present the first reported case of sebaceous adenoma of the palate, to our knowledge.Method:Case report and review of the English language literature, with a focus on the pathological spectrum of sebaceous glands.Case report:A woman presented with a growth on the hard palate, which was excised and examined. Histopathological analysis showed features of sebaceous adenoma. Further evaluation with Sudan Black B special stains and Ki 67 immunohistochemistry was performed.Conclusion:Sebaceous adenomas in the oral cavity are very rare, with only 10 cases previously reported in t
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33

Kashkary, Suhail Mohammed, Saood Faisal Almutairi, Alzahraa Ahmed Alkhars, et al. "Sebaceous gland diseases: clinical picture risk factors and treatment." International Journal Of Community Medicine And Public Health 10, no. 10 (2023): 3904–9. http://dx.doi.org/10.18203/2394-6040.ijcmph20233130.

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Sebaceous glands are present in almost every part of the skin or body except the palms and soles, and the primary function of these glands involves the generation of sebum. However, numerous diseases, both benign and malignant, have been linked to abnormal sebaceous gland activity. Sebaceous gland disorders are a class of widespread dermatological conditions with numerous aetiologies. Diseases in which the primary involvement is associated with sebaceous glands comprise conditions such as steatocystoma, sebaceous gland hyperplasia, sebaceoma, sebaceous adenoma, nevus sebaceous, and sebaceous c
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34

Fatema, Kanij, Mizanur Rahman, Shaheen Akhter, and Roushan Jahan. "Tuberous sclerosis complex associated neuropsychiatric disorder in children: experience sharing from a tertiary care hospital." International Journal of Contemporary Pediatrics 8, no. 6 (2021): 961. http://dx.doi.org/10.18203/2349-3291.ijcp20212034.

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Background: Tuberous sclerosis complex (TSC) is a genetic disorder where there is multisystem involvement. Most important manifestations are neurological and psychiatric disorders. These disorders should be detected timely and addressed adequately. The common psychiatric disorders are autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), intellectual disability (ID), learning disorder etc. This study has been done to describe the pattern of psychiatric disorders in children with TSC.Methods: This is an observational study taken place in a tertiary care hospital taken
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35

Kumar, R., D. Milford, L. Kerecuk, and SG Philip. "G115(P) Use of mTOR inhibitors in children with tuberous sclerosis complex for renal angiomyolipomatosis – does it have secondary benefits on seizures and adenoma sebaceum?" Archives of Disease in Childhood 101, Suppl 1 (2016): A64.2—A64. http://dx.doi.org/10.1136/archdischild-2016-310863.111.

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36

Papadimitriou, Ilias, Efstratios Vakirlis, Elena Sotiriou, Katerina Bakirtzi, Aimilios Lallas, and Demetrios Ioannides. "Sebaceous Neoplasms." Diagnostics 13, no. 10 (2023): 1676. http://dx.doi.org/10.3390/diagnostics13101676.

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Sebaceous neoplasms describe a group of tumors with sebaceous differentiation commonly seen in lesions located primarily in the face and neck. The majority of these lesions are benign, while malignant neoplasms with sebaceous differentiation are uncommon. Sebaceous tumors present a strong association with the Muir–Torre Syndrome. Patients suspected with this syndrome should undergo neoplasm excision, followed by histopathologic and additional immunohistochemistry and genetics examinations. Clinical and dermoscopic features of the sebaceous neoplasms, as well as management procedures collected
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37

Sewoyo, Palagan Senopati, and Willy Moris Nainggolan. "Sebaceous Adenoma Case in a Golden Retriever Dog." Journal of Applied Veterinary Science And Technology 4, no. 2 (2023): 122–26. http://dx.doi.org/10.20473/javest.v4.i2.2023.122-126.

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Background: Sebaceous adenoma is a benign tumour originating from the skin's sebaceous glands. These tumours can arise in older and middle-aged dogs, typically on various body parts, head, and extremities. The tumours can manifest as either lumps or ulcers. Ulcers may develop when the animal scratches the tumour mass. Purpose: Increase the insight and ability of veterinary practitioners in diagnosing and providing information regarding the treatment of sebaceous adenomas. Case: A nine-year-old Golden retriever dog was brought to the Bali Veterinary Clinic with a complaint of a lateral wound on
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38

Gupta, Siddharth, Rahul Bhowate, and Shirish S. Degwekar. "Clinical and Radiological Findings Related to Tuberous Sclerosis Complex: A Case Report." Journal of Contemporary Dental Practice 9, no. 4 (2008): 85–91. http://dx.doi.org/10.5005/jcdp-9-4-85.

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Abstract Aim The aim of this report is to present the intraoral and extraoral clinical features of a young female patient with tuberous sclerosis complex (TSC) who exhibited multiple hamartomas of various organ systems including a fibromatous growth on the gingiva. Background TSC is a rare neurocutaneous syndrome exhibiting multiple hamartomatous proliferations that may involve multiple organs such as the brain, kidney, heart, eyes, lungs and skin. Oral manifestations such as enamel pitting and fibromatous growth of the gingiva are commonly seen in patients with TSC. Report A 16-year-old femal
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39

Scotti, B., E. Campione, and E. Dika. "Unmasking sebaceous tumors. Dermoscopic characteristics of sebaceous adenoma, sebaceoma and sebaceous carcinoma: a systematic review." EJC Skin Cancer 3 (2025): 100659. https://doi.org/10.1016/j.ejcskn.2025.100659.

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40

Elmore, Robert A., Mary K. Dick, and Poonam K. Sharma. "Muir-Torre syndrome: the curious case of wobbly microsatellites and their mucosal Lynch." International Journal of Research in Dermatology 5, no. 3 (2019): 646. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20193244.

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<p>MSH2 mismatch repair gene is commonly associated with Lynch syndrome; however, Lynch syndrome’s phenotypic variant, Muir-Torre syndrome is a lesser known entity comprising a spectrum of benign to malignant sebaceous neoplasms and is often the first etiology of a more significant prodromal syndrome. Both syndromes encompass gastrointestinal, genitourinary tract, and prostatic pathologies. We present a 15-year patient progression starting with new sebaceous hyperplasia and congenital melanocytic nevus skin lesions presenting in a 38-year-old caucasian male. After approximately four year
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41

Baker, Gabrielle M., M. Angelica Selim, and Mai P. Hoang. "Vulvar Adnexal Lesions: A 32-Year, Single-Institution Review From Massachusetts General Hospital." Archives of Pathology & Laboratory Medicine 137, no. 9 (2013): 1237–46. http://dx.doi.org/10.5858/arpa.2012-0434-oa.

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Context.—Because the skin and modified mucosal surfaces of the vulvar region contain dense apocrine glands and anogenital mammary-like glands, in addition to eccrine glands and folliculosebaceous units, benign as well as malignant lesions derived from these adnexal structures are, not surprisingly, found in the vulva. However, their incidence occurring in the vulva has not been reported, to our knowledge. Objective.—To determine the incidence of various vulvar adnexal lesions. Design.—We performed a retrospective review (1978–2010) of the cases at our institution. Results.—A total of 189 vulva
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42

Herr, Gyula, Mária Szenes, Györgyi Hohl, et al. "A jéghegy csúcsa: multiplex faggyúmirigy-eredetű bőrtumor coloncarcinomában. Muir–Torre-szindróma." Orvosi Hetilap 156, no. 24 (2015): 979–84. http://dx.doi.org/10.1556/650.2015.30165.

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Muir–Torre syndrome is a rare genodermatosis with autosomal dominant inheritance. The syndrome is considered to be a subtype of the hereditary nonpolyposis colorectal cancer (or Lynch-syndrome). In two-third of the cases, it develops as the consequence of germline mutations in mismatch-repair genes – most commonly MutS Homolog-2 and MutL Homolog-1. Its diagnosis can be established if at least one sebaceous tumor (sebaceoma, sebaceous adenoma, epithelioma, carcinoma or basal-cell carcinoma with sebaceous differentiation) and/or keratoacanthoma and at least one internal neoplasm are present. Her
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Terrell, Shaundre, Robyn Wetter, Garth Fraga, Thelda Kestenbaum, and Daniel J. Aires. "Penile sebaceous adenoma." Journal of the American Academy of Dermatology 57, no. 2 (2007): S42—S43. http://dx.doi.org/10.1016/j.jaad.2006.12.020.

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Niu, Dongfeng, Yanhua Bai, Qian Yao, et al. "Expression and Significance of AQP3 in Cutaneous Lesions." Analytical Cellular Pathology 2021 (October 26, 2021): 1–6. http://dx.doi.org/10.1155/2021/7866471.

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Aquaporin 3 (AQP3) is the membrane channel of water and involved in fluid homeostasis. The aim of this study was to reveal the expression and significance of AQP3 in cutaneous lesions. We analyzed AQP3 mRNA levels using RT-PCR in 311 cutaneous lesions and confirmed AQP3 expression in these lesions by immunohistochemistry. AQP3 mRNA was detected in normal epidermis, seborrheic keratosis, solar keratosis, Bowen’s disease, squamous cell carcinoma, eccrine poroma, apocrine carcinoma, and sebaceoma; however, AQP3 mRNA was absent in basal cell carcinoma, nevocellular nevus, or malignant melanoma. By
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45

Pooja, V. Patil. "Sebaceous Adenoma of Eyelid." International Journal of Medical and Pharmaceutical Research 4, no. 3 (2023): 77–79. https://doi.org/10.5281/zenodo.7927775.

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<strong>Aims</strong>: To report a case of Sebaceous Adenoma of eyelid in 30 years old male and its diagnosis and management. <strong>Case Report</strong>: We described a case of 30yr old male patient presented to our hospital complaining of swelling over medial part of the left lower eyelid since 1year. Patient was suspected as left eye sebaceous cyst. He underwent complete surgical excision with histopathological examination of the sample. <strong>Result</strong>: We diagnosed the case postoperatively as a Sebaceous Adenoma of left eyelid based on histopathological examination. <strong>Concl
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Yasui, S., I. Ando, A. Kukita, H. Hino, and K. Ohara. "DF3 (CA15-3) antibody as a marker of cutaneous adnexal tumors." Acta Dermato-Venereologica 74, no. 2 (1994): 98–100. http://dx.doi.org/10.2340/0001555574183187.

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DF3(CA15-3) monoclonal antibody detects the 20 amino acid sequence of epithelial mucin. In normal cutaneous tissue DF3 antibody exhibits strong and constant positive reactivity with sebaceous and secretory segments of eccrine and apocrine sweat glands. All epidermal tumors are DF3 negative but poorly differentiated squamous cell carcinoma. Various adnexal tumors such as eccrine hidrocystoma, tubular apocrine adenoma, syringocystadenoma papilliferum, eccrine poroma, eccrine spiradenoma, clear cell hidradenoma, mixed cell tumor, eccrine porocarcinoma, extramammary Paget's disease and adenoid cys
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Yang, Yu, Shweta Dhar, Jennifer Taylor, and Bhuvaneswari Krishnan. "Papillary Renal Cell Carcinoma in Lynch/Muir-Torre Syndrome with Germline Pathogenic Variant in MSH6 and Molecular Analysis." Journal of Kidney Cancer and VHL 8, no. 2 (2021): 8–19. http://dx.doi.org/10.15586/jkcvhl.v8i2.175.

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Lynch syndrome (LS) is an autosomal dominant inherited disorder due to pathogenic variations in the mismatch repair genes, which predisposes to malignancies, most commonly colon and endometrial carcinoma. Muir-Torre syndrome is a subset of LS with cutaneous sebaceous adenoma and keratoacanthoma in addition to the malignancies. Renal cell carcinoma (RCC) in patients with LS is extremely rare. Only 26 cases have been reported and among them, only two cases of papillary RCC. We report a case of synchronous papillary RCC and colonic adenocarcinoma in an 85-year-old male with Lynch/Muir-Torre syndr
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Tok, Levent, Ozlem Yalcin Tok, Mehmet Argun, I. Metin Ciris, Sirin Baspinar, and Alime Gunes. "Corneal Limbal Sebaceous Adenoma." Cornea 33, no. 4 (2014): 425–27. http://dx.doi.org/10.1097/ico.0000000000000075.

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Han, Bo Sook, and Min Joung Lee. "A Case of Sporadic Eyelid Sebaceous Adenoma." Journal of the Korean Ophthalmological Society 63, no. 8 (2022): 707–11. http://dx.doi.org/10.3341/jkos.2022.63.8.707.

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Purpose: To report a case of sebaceous adenoma, which is a rare benign eyelid tumor.Case summary: A 45-year-old male presented with a visible mass on his left upper eyelid that had recurred 2 months ago. The mass had been resected 2 years ago. When the upper eyelid was everted, the tarsal portion of the mass was visible as a whitish papillary lesion. An incisional biopsy was done for pathological diagnosis and sebaceous adenoma was confirmed based on histopathological examinations. Subsequently, complete excision of the mass and eyelid reconstruction were performed under general anesthesia. Im
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Raizada, R. M., and N. U. Khan. "Aural sebaceous adenomas." Journal of Laryngology & Otology 100, no. 12 (1986): 1413–16. http://dx.doi.org/10.1017/s0022215100101203.

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