Academic literature on the topic 'Adenosine Deaminase; Rhubarb; Cancer'

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Journal articles on the topic "Adenosine Deaminase; Rhubarb; Cancer"

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Zahide, Esra Durak, Büber Süleyman, Devrim Erdinç, Kocaoğlu Hilmi, and Durak İlker. "Aquoeus Extract from Rhubarb Plant Inhibits Adenosine Deaminase Activity in Cancerous and Non Cancerous Human Gastric and Colon Tissues." Journal of Progressive Research in Chemistry 1, no. 1 (2015): 9–13. https://doi.org/10.5281/zenodo.3970308.

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Aim: Investigation of possible effects of rhubarb extract on adenosine deaminase (ADA) activity in cancerous and non cancerous human gastric and colon tissues to obtain information about possible mechanism of anti cancer action of rhubarb. Materials and methods: Cancerous and non cancerous human gastric and colon tissues removed from patients by surgical operations were used in the studies. The extracts were prepared in distilled water. Before and after treatment with the extracts, ADA activities in the tissue homogenates were measured. Results: ADA activity was found to be higher in gastric t
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Zhulai, Galina, Eugenia Oleinik, Mikhail Shibaev, and Kirill Ignatev. "Adenosine-Metabolizing Enzymes, Adenosine Kinase and Adenosine Deaminase, in Cancer." Biomolecules 12, no. 3 (2022): 418. http://dx.doi.org/10.3390/biom12030418.

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The immunosuppressive effect of adenosine in the microenvironment of a tumor is well established. Presently, researchers are developing approaches in immune therapy that target inhibition of adenosine or its signaling such as CD39 or CD73 inhibiting antibodies or adenosine A2A receptor antagonists. However, numerous enzymatic pathways that control ATP-adenosine balance, as well as understudied intracellular adenosine regulation, can prevent successful immunotherapy. This review contains the latest data on two adenosine-lowering enzymes: adenosine kinase (ADK) and adenosine deaminase (ADA). ADK
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Shatova, O. P., Eu V. Butenko, Eu V. Khomutov, D. S. Kaplun, I. Eu Sedakov, and I. I. Zinkovych. "Metformin impact on purine metabolism in breast cancer." Biomeditsinskaya Khimiya 62, no. 3 (2016): 302–5. http://dx.doi.org/10.18097/pbmc20166203302.

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Large-scale epidemiological and clinical studies have demonstrated the efficacy of metformin in oncology practice. However, the mechanisms of implementation of the anti-tumor effect of this drug there is still need understanding. In this study we have investigated the effect of metformin on the activity of adenosine deaminase and respectively adenosinergic immunosuppression in tumors and their microenvironment. The material of the study was taken during surgery of breast cacer patients receiveing metformin, and also patients which did not take this drug. The adenosine deaminase activity and su
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Namiot, Z., A. Kemona, J. Stasiewicz, M. Marcinkiewicz, A. Namiot, and J. Gorski. "Adenosine deaminase activity in gastric cancer." Cancer Letters 82, no. 1 (1994): 95–98. http://dx.doi.org/10.1016/0304-3835(94)90151-1.

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Journal, Baghdad Science. "Chemotherapy Effects on the Activities of Some Purine Metabolic Enzymes in Sera of Ovarian Cancer Patients." Baghdad Science Journal 7, no. 3 (2010): 1166–73. http://dx.doi.org/10.21123/bsj.7.3.1166-1173.

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Adenosine deaminase (ADA; Ec: 3.5.4.4), 5´- Nucleotidase (5´– NT; Ec: 3.1.3.5), and AMP – amino hydrolase (AMP – deaminase AMPDA; Ec: 3.5.4.6) activities were measured in sera of ovarian cancer patients before surgery, and after chemotherapy. The results indicated that ADA specific activity increased significantly (P
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Al-Shammaree, Shatha Abd AL Wadood. "Chemotherapy Effects on the Activities of Some Purine Metabolic Enzymes in Sera of Ovarian Cancer Patients." Baghdad Science Journal 7, no. 3 (2010): 1166–73. http://dx.doi.org/10.21123/bsj.2010.7.3.1166-1173.

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Adenosine deaminase (ADA; Ec: 3.5.4.4), 5´- Nucleotidase (5´– NT; Ec: 3.1.3.5), and AMP – amino hydrolase (AMP – deaminase AMPDA; Ec: 3.5.4.6) activities were measured in sera of ovarian cancer patients before surgery, and after chemotherapy. The results indicated that ADA specific activity increased significantly (P
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Yildirim, Zeki, H. Canan Hasanoglu, Ömer Akyol, Münire Gokirmak, and Nurhan Köksal. "Serum adenosine deaminase activities in lung cancer and mesothelioma." Clinical Biochemistry 32, no. 4 (1999): 283–85. http://dx.doi.org/10.1016/s0009-9120(99)00013-2.

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Wang, Lin, Luz M. Londono, Jessica Cowell, et al. "Targeting Adenosine with Adenosine Deaminase 2 to Inhibit Growth of Solid Tumors." Cancer Research 81, no. 12 (2021): 3319–32. http://dx.doi.org/10.1158/0008-5472.can-21-0340.

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YOKOYAMA, M. M., and I. TSUBOI. "Adenosine Deaminase Isoenzymes and HIV/HTLV-1 Infections." JNCI Journal of the National Cancer Institute 80, no. 9 (1988): 698. http://dx.doi.org/10.1093/jnci/80.9.698.

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Lee, Su-Chan, Lujain Alaali, HyukJean Kwon, Mohammed Rigi, and Charles G. Eberhart. "Abstract 1868: Targeting adenosine deaminase enhances anticancer effects of 3'-deoxyadenosine in uveal melanoma." Cancer Research 82, no. 12_Supplement (2022): 1868. http://dx.doi.org/10.1158/1538-7445.am2022-1868.

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Abstract Uveal melanoma, which arises from melanocytes located in the uveal tract, is one of the most common primary intraocular cancers. GNAQ and GNA11 mutations, which are detected most of primary uveal melanoma, activate MAPK signaling pathway, increasing cancer cell proliferation, tumor progression and growth. BAP1 mutation is highly associated with liver metastasis and death. However, there are no good therapeutic compounds for uveal melanoma treatment in clinic. 3’-deoxyadenosine (cordycepin) is an adenosine analog which inhibits growth of several types of cancer. However, its anticancer
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Dissertations / Theses on the topic "Adenosine Deaminase; Rhubarb; Cancer"

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Samee, Abdus. "An analysis of the ADAT1 (adenosine deaminase, tRNA- specific 1) gene in cancer." Thesis, Keele University, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530765.

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Books on the topic "Adenosine Deaminase; Rhubarb; Cancer"

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Kate, Johannes ten. Adenosine deaminase complexing protein as a marker in cancer studies. [s.n.], 1985.

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Book chapters on the topic "Adenosine Deaminase; Rhubarb; Cancer"

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Sarin, P. S., A. Thornton, and D. Sun. "Terminal Transferase and Adenosine Deaminase Activities in Human Neoplasia: Their Role in Modulating Cancer Treatment." In New Experimental Modalities in the Control of Neoplasia. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5242-6_14.

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Russo, Michele, Teresa Pizzella, Gaetano Liguori, Salvatore Nardiello, and Bruno Galanti. "Changes in Lymphocyte Adenosine Deaminase and Purine Nucleoside Phosphorylase Levels in Lung Cancer after Radical Surgery." In Purine and Pyrimidine Metabolism in Man V. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5104-7_85.

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"Adenosine Deaminase." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_90.

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Avci, Aslihan, and Ilker Durak. "Tomato Juice, Prostate Cancer and Adenosine Deaminase Enzyme." In Tomatoes and Tomato Products. CRC Press, 2008. http://dx.doi.org/10.1201/9781439843390-23.

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Avci, Aslihan, and Ilker Durak. "Tomato Juice, Prostate Cancer and Adenosine Deaminase Enzyme." In Tomatoes and Tomato Products. Science Publishers, 2008. http://dx.doi.org/10.1201/9781439843390-c23.

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Svensjo, Tor, Feng Yao, Bohdan Pomahac, and Elof Eriksson. "Gene therapy applications of growth factors." In Growth Factors and Receptors. Oxford University PressOxford, 1998. http://dx.doi.org/10.1093/oso/9780199636471.003.0010.

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Abstract Gene therapy (GTh) involves transfer of DNA to somatic cells with the purpose of getting those cells to express certain proteins or antisense RNA. Currently all protocols for GTh are experimental, but with the ultimate goal of curing patients. Remarkable progress has marked the field of GTh in the past decade. Since the first Recombinant DNA Advisory Committee (RAC) approved treatment that employed gene transfer (GTr) to study and treat human disease (1) the number of clinical trials involving GTh has increased exponentially, and as of March 1996 there were 145 approved human GTh prot
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Friedmann, Theodore. "Finally—breakthrough success?" In The Origin and Development of Genetic Therapies. Oxford University PressNew York, 2025. https://doi.org/10.1093/med/9780197689974.003.0019.

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Abstract The first virus-based gene therapy to reach the commercial market was Gendicine, a Chinese product intended to express the tumor suppressor gene p53 in patients with head and neck cancer. Despite its use in large clinical studies in China, Gendicine and similar agents being studied in the United States did not achieve approval or broad use. The first credible apparent success in Western medical settings came in 2002 in studies of the X-linked form of severe immunodeficiency disease (SCID) being carried out by Fischer in Paris and colleagues in London. But despite very exciting disease
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Conference papers on the topic "Adenosine Deaminase; Rhubarb; Cancer"

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Saatci, Ozge, Luz Marina Londoño, Renee Clift, et al. "Abstract A84: Clinical correlates and rationale for PEGylated adenosine deaminase 2 as a novel cancer immunotherapy." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 17-20, 2019; Boston, MA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm19-a84.

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