Academic literature on the topic 'Adenosine triphosphatase genes Expression'

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Journal articles on the topic "Adenosine triphosphatase genes Expression"

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Dvorak, Pavel, Martin Pesta, and Pavel Soucek. "ABC gene expression profiles have clinical importance and possibly form a new hallmark of cancer." Tumor Biology 39, no. 5 (2017): 101042831769980. http://dx.doi.org/10.1177/1010428317699800.

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Adenosine triphosphate–binding cassette proteins constitute a large family of active transporters through extracellular and intracellular membranes. Increased drug efflux based on adenosine triphosphate–binding cassette protein activity is related to the development of cancer cell chemoresistance. Several articles have focused on adenosine triphosphate–binding cassette gene expression profiles (signatures), based on the expression of all 49 human adenosine triphosphate–binding cassette genes, in individual tumor types and reported connections to established clinicopathological features. The ai
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Ojamaa, K., A. M. Samarel, J. M. Kupfer, C. Hong, and I. Klein. "Thyroid hormone effects on cardiac gene expression independent of cardiac growth and protein synthesis." American Journal of Physiology-Endocrinology and Metabolism 263, no. 3 (1992): E534—E540. http://dx.doi.org/10.1152/ajpendo.1992.263.3.e534.

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Prior studies have demonstrated the importance of hemodynamic loading in mediating thyroxine (T4)-induced cardiac hypertrophy. Direct cellular effects of thyroid hormone have been implicated in modulating the expression of the myosin heavy chain (MHC) genes and the slow sarcoplasmic reticulum calcium adenosine triphosphatase (SR Ca(2+)-ATPase) gene. In the present report, administration of T4 for 72 h did not stimulate growth of the hemodynamically unloaded heterotopic isograft. The synthetic rates of total cardiac proteins and MHC in the isograft remained significantly lower at 64 and 53% of
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Habib, Tania, Heon Park, Mark Tsang, et al. "Myc stimulates B lymphocyte differentiation and amplifies calcium signaling." Journal of Cell Biology 179, no. 4 (2007): 717–31. http://dx.doi.org/10.1083/jcb.200704173.

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Deregulated expression of the Myc family of transcription factors (c-, N-, and L-myc) contributes to the development of many cancers by a mechanism believed to involve the stimulation of cell proliferation and inhibition of differentiation. However, using B cell–specific c-/N-myc double-knockout mice and Eμ-myc transgenic mice bred onto genetic backgrounds (recombinase-activating gene 2−/− and Btk−/− Tec−/−) whereby B cell development is arrested, we show that Myc is necessary to stimulate both proliferation and differentiation in primary B cells. Moreover, Myc expression results in sustained
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Davis, Lowell, James Musso, Divya Soman, Samantha Louey, Jonathan W. Nelson, and Sonnet S. Jonker. "Role of adenosine signaling in coordinating cardiomyocyte function and coronary vascular growth in chronic fetal anemia." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 315, no. 3 (2018): R500—R508. http://dx.doi.org/10.1152/ajpregu.00319.2017.

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Fetal anemia causes rapid and profound changes in cardiac structure and function, stimulating proliferation of the cardiac myocytes, expansion of the coronary vascular tree, and impairing early contraction and relaxation. Although hypoxia-inducible factor-1α is sure to play a role, adenosine, a metabolic byproduct that increases coronary flow and growth, is implicated as a major stimulus for these adaptations. We hypothesized that genes involved in myocardial adenosine signaling would be upregulated in chronically anemic fetuses and that calcium-handling genes would be downregulated. After ste
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Aubier, M., and N. Viires. "Calcium ATPase and respiratory muscle function." European Respiratory Journal 11, no. 3 (1998): 758–66. http://dx.doi.org/10.1183/09031936.98.11030758.

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The sarcoplasmic reticulum (SR) of striated muscle is a highly specialized intracellular membrane system that plays a key role in the contraction-relaxation cycle of muscle. Its primary function is the regulation of cytoplasmic Ca2+ concentration. A key element in this regulation is the Sarco(endo)plasmic reticulum Ca2+-adenosine triphosphatase (SERCA), which by sequestering Ca2+ into the SR, induces and maintains relaxation. It has been extensively studied with respect to structure and mechanism of action, and more recently to gene expression. Three separate genes encode five SERCA isoforms,
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Li, Jiajia, Xionghui Li, Hong Huang, et al. "Role of SERCA3 in the Prognosis and Immune Function in Pan-Cancer." Journal of Oncology 2022 (November 4, 2022): 1–12. http://dx.doi.org/10.1155/2022/9359879.

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The sarcoendoplasmic reticulum calcium adenosine triphosphatase (ATPase) 3 (SERCA3), a member of the SERCA protein family, is located at the endoplasmic reticulum. Its main function is to pump Ca2+ into the endoplasmic reticulum and is involved in maintaining intracellular calcium homeostasis and signal transduction, which are very important factors impacting cancer development and progression. However, the specific role of SERCA3 in cancer remains unclear. Our study, for the first time, comprehensively analyzed the SERCA3 expression profile in multiple cancers and its prognostic value in diff
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Nemtsova, M. V., and I. V. Bure. "Targeting of the SWI/SNF chromatin remodeling complex in cancer therapy." Advances in Molecular Oncology 10, no. 1 (2023): 8–17. http://dx.doi.org/10.17650/2313-805x-2023-10-1-8-17.

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Chromatin remodeling is the one of the main epigenetic ways of gene expression regulation both in normal cells and in oncological diseases. Genes encoding protein subunits of SWI/ SNF remodeling complexes often mutate and/or change their expression in human tumors, affecting the expression programs of many genes during carcinogenesis, which is associated with the occurrence and progression of cancer. Today, there are no therapeutic drugs that could directly change the structure of chromatin because of complexity of this process with involvement of a large number of genes, proteins, non-coding
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Mahajan, Milind C., та Sherman M. Weissman. "DNA-dependent adenosine triphosphatase (helicaselike transcription factor) activates β-globin transcription in K562 cells". Blood 99, № 1 (2002): 348–56. http://dx.doi.org/10.1182/blood.v99.1.348.

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Correct developmental regulation of β-like globin gene expression is achieved by preferential transcription of a gene at a given developmental stage, silencing of other β-like gene promoters, and competition among these promoters for interaction with the locus control region (LCR). Several evolutionarily conserved DNA elements in the promoters of the β-like genes and LCR have been studied in detail, and the role of their binding factors has been investigated. However, the β-globin promoter includes additional evolutionarily conserved sequences of unknown function. The present study examined th
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Varchenko, O., M. Kuchuk, M. Parii, and Y. Symonenko. "Matching of the GFP Gene Expression Levels by Different Terminator Sequences Regulation." Mikrobiolohichnyi Zhurnal 82, no. 6 (2020): 74–83. http://dx.doi.org/10.15407/microbiolj82.06.074.

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The ability to express foreign genes in plant cells provides a powerful tool for studying the function of specific genes. In addition, the creation of genetically modified plants may provide new important features that are useful for industrial production or pharmaceutical applications. One of the key parameters for the development of a high level of heterologous genes expression is the efficiency of terminators used in genetic engineering, since the level of gene expression depends on its choice. Aim. Study of the gfp gene expression regulation in Nicotiana rustica L. tissues by different ter
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Singer, Thomas D., Koreen M. Clements, Jeffrey W. Semple, et al. "Seawater tolerance and gene expression in two strains of Atlantic salmon smolts." Canadian Journal of Fisheries and Aquatic Sciences 59, no. 1 (2002): 125–35. http://dx.doi.org/10.1139/f01-205.

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The seawater tolerance of Atlantic salmon (Salmo salar) smolts reared under identical hatchery conditions was assessed in two Norwegian strains: AquaGen and Imsa. Plasma ion levels were disrupted in both strains following seawater exposure, but these disruptions were more profound in the AquaGen fish. To investigate the mechanisms underlying these differences, we measured gill Na+,K+-adenosine triphosphatase (ATPase) activity and mRNA levels of Na+,K+-ATPase α-subunit and two isoforms of the cystic fibrosis transmembrane conductance regulator (CFTR). Gill Na+,K+-ATPase activity rose significan
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Dissertations / Theses on the topic "Adenosine triphosphatase genes Expression"

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Jain, Nishant Rajkumar. "Characterization and functional analysis of the P2Y₂R gene promoter." Diss., Columbia, Mo. : University of Missouri-Columbia, 2006. http://hdl.handle.net/10355/4629.

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Thesis (M.S.)--University of Missouri-Columbia, 2006.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on April 21, 2009) Includes bibliographical references.
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Reifur, Larissa. "Structural and thermodynamic studies of the ATPase subunit 6 mRNA/gRNA complex in Trypanosoma brucei." Diss., Connect to online resource - MSU authorized users, 2008.

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Thesis (PH.D.)--Michigan State University. Comparative Medicine and Integrative Biology, 2008.<br>Title from PDF t.p. (viewed on Aug. 11, 2009) Includes bibliographical references. Also issued in print.
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Fazzio, Thomas G. "Isw2 complex slides nucleosomes to create repressive chromatin structure in vivo /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/5092.

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Fortier, Louis-Charles. "Cloning and characterization of the genes encoding Oenococcus oeni H+-ATPase and Cu+-ATPase." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=36927.

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Two enzymatic systems from the lactic acid bacterium Oenococcus oeni, isolated from wine, have been studied. The first one is the H+-ATPase for which the activity was characterized under various conditions of growth. The activity gradually increased by l.6 to 1.9-fold upon inoculation at pH 3.5. The H+-ATPase activity did not vary significantly in function of the growth rate or with and without malic acid. However, acidification of the medium in the absence of malic acid induced the activity by 1.5 to 2.2-fold depending on the initial pH. The partially cloned H+-ATPase genes shared high homolo
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Jaskelioff, Mariela. "Mechanistic Analysis of Chromatin Remodeling Enzymes: a Dissertation." eScholarship@UMMS, 2003. https://escholarship.umassmed.edu/gsbs_diss/55.

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The inherently repressive nature of chromatin presents a sizeable barrier for all nuclear processes in which access to DNA is required. Therefore, eukaryotic organisms ranging from yeast to humans rely on a battery of enzymes that disrupt the chromatin structure as a means of regulating DNA transactions. These enzymes can be divided into two broad classes: those that covalently modify histone proteins, and those that actively disrupt nucleosomal structure using the free energy derived from ATP hydrolysis. The latter group, huge, multisubunit ATP-dependent chromatin remodeling factors, are emer
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Vendrell, Arasa Alexandre. "SCF cdc4 regulates msn2 and msn4 dependent gene expression to counteract hog1 induced lethality." Doctoral thesis, Universitat Pompeu Fabra, 2009. http://hdl.handle.net/10803/7153.

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L'activació sostinguda de Hog1 porta a una inhibició del creixement cel·lular. En aquest treball, hem observat que el fenotip de letalitat causat per l'activació sostinguda de Hog1 és parcialment inhibida per la mutació del complexe SCFCDC4. La inhibició de la mort causada per l'activació sostinguda de Hog1 depèn de la via d'extensió de la vida. Quan Hog1 s'activa de manera sostinguda, la mutació al complexe SCFCDC4 fa que augmenti l'expressió gènica depenent de Msn2 i Msn4 que condueix a una sobreexpressió del gen PNC1 i a una hiperactivació de la deacetilassa Sir2. La hiperactivació de Sir2
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Munn, Alan Leslie. "Expression and functional analysis of spinach chloroplast ATP synthase subunits in Escherichia coli K12." Phd thesis, 1988. http://hdl.handle.net/1885/141184.

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Mason, John G. "Isolation and characterization of cDNAs and the gene coding for the [gamma]-subunit of spinach chloroplast ATP synthase." Phd thesis, 1989. http://hdl.handle.net/1885/141085.

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Mackenzie, Susan Margaret. "Studies of the white and scarlet proteins of Drosophila melanogaster." Phd thesis, 1999. http://hdl.handle.net/1885/148021.

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Books on the topic "Adenosine triphosphatase genes Expression"

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International, Seminar/Workshop on the Molecular Structure Function and Assembly of ATP Synthases (1987 Honolulu Hawaii). Molecular structure, function, and assembly of the ATP synthases. Plenum Press, 1989.

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Marzuki, Sangkot. Molecular Structure, Function, and Assembly of the Atp Synthesis: International Seminar. Springer, 1990.

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Book chapters on the topic "Adenosine triphosphatase genes Expression"

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G, E. B. "Expression and Localization of A2a and Al-Adenosine Recretor Genes in the Rat Carotid Body and Petrosal Ganglia." In Oxygen Sensing. Springer US, 2002. http://dx.doi.org/10.1007/0-306-46825-5_53.

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Hayashi, Taro, Katsunori Ogoh, and Hirobumi Suzuki. "Imaging Promoter Assay of Adenylyl Cyclase A Gene in Dictyostelium discoideum during Fruiting Body Formation by Dual-Color Bioluminescence Microscopy." In Bioluminescence - Technology and Biology. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.101485.

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Cyclic adenosine monophosphate (cAMP), which is derived from adenosine triphosphate through adenylyl cyclase A (acaA), acts as an intracellular secondary messenger and an extracellular chemotactic substance in important biological processes. In the social amoebae Dictyostelium discoideum, cAMP mediates cell aggregation, development, and differentiation to spore and stalk cells during fruiting body formation. The acaA gene is transcribed under the control of three different alternative promoters. This study aimed to develop a promoter assay for acaA in D. discoideum using bioluminescence micros
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Villela-Peña, Atenas, and Miguel Guillermo Flores Padilla. "Lactic Acidosis and Lymphoma." In Advances in Hematological Malignancies [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.110341.

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Warburg effect in tumor cells describes the increased rate of glucose metabolism in anaerobic conditions and a secondary lactic acid production, known as aerobic glycolysis. The reason to engage in this metabolic pathway is that neoplastic cells need adenosine triphosphate (ATP) and other metabolites to keep growing via anaerobic glycolysis, and this is faster than the tricarboxylic acid cycle; besides, the anaerobic glycolysis avoids the apoptosis mediated by reactive oxygen species (anoikis). The Warburg effect is different in each type of tumor, for example, lymphoma, ovarian, and lung canc
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Candotti, Fabio, and Alain Fischer. "Gene Therapy." In Primary Immunodeficiency Diseases. Oxford University PressNew York, NY, 2006. http://dx.doi.org/10.1093/oso/9780195147742.003.0048.

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Abstract As currently practiced, gene therapy can be defined as the transfer of exogenous genes to somatic cells of a patient in order to correct an inherited or acquired gene defect, or to introduce a new function or trait. In the last 15 years, gene therapy has moved from the speculative stage to clinical applications as clinical gene transfer protocols have been applied to inherited genetic defects, malignancies, and infectious diseases. Primary immunodeficiciency diseases (PIDs), especially severe combined immunodeficiency (SCID) disorders, have played a major role in this process as they
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Reports on the topic "Adenosine triphosphatase genes Expression"

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Osathanon, Thanaphum. Gene expression profile of continuous and intermittent compressive stress treated human periodontal ligament cells. Faculty of Dentistry Chulalongkorn University, 2019. https://doi.org/10.58837/chula.res.2019.7.

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Mechanical force regulates periodontal ligament cell (PDL) behavior. However, different force types lead to distinct PDL responses. Here, we report that pretreatment with an intermittent compressive force (ICF), but not a continuous compressive force (CCF), promoted human PDL (hPDL) osteogenic differentiation as determined by osteogenic marker gene expression and mineral deposition in vitro. ICF-induced osterix (OSX) expression was inhibited by cycloheximide and monensin. Although CCF and ICF significantly increased extracellular adenosine triphosphate (ATP) levels, pretreatment with exogenous
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