Academic literature on the topic 'Adiponectin/leptin'

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Journal articles on the topic "Adiponectin/leptin"

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Zhao, Shangang, Christine M. Kusminski, and Philipp E. Scherer. "Adiponectin, Leptin and Cardiovascular Disorders." Circulation Research 128, no. 1 (2021): 136–49. http://dx.doi.org/10.1161/circresaha.120.314458.

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The landmark discoveries of leptin and adiponectin firmly established adipose tissue as a sophisticated and highly active endocrine organ, opening a new era of investigating adipose-mediated tissue crosstalk. Both obesity-associated hyperleptinemia and hypoadiponectinemia are important biomarkers to predict cardiovascular outcomes, suggesting a crucial role for adiponectin and leptin in obesity-associated cardiovascular disorders. Normal physiological levels of adiponectin and leptin are indeed essential to maintain proper cardiovascular function. Insufficient adiponectin and leptin signaling
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Bocian-Jastrzębska, Agnes, Anna Malczewska-Herman, Violetta Rosiek, and Beata Kos-Kudła. "Assessment of the Role of Leptin and Adiponectinas Biomarkers in Pancreatic Neuroendocrine Neoplasms." Cancers 15, no. 13 (2023): 3517. http://dx.doi.org/10.3390/cancers15133517.

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Data on the possible connection between circulating adipokines and PanNENs are limited. This novel study aimed to assess the serum levels of leptin and adiponectin and their ratio in patients with PanNENs and to evaluate the possible relationship between them and PanNEN’s grade or stage, including the presence of metastases. The study group consisted of PanNENs (n = 83), and healthy controls (n = 39). Leptin and adiponectin measurement by an ELISA assay was undertaken in the entire cohort. The serum concentration of adiponectin was significantly higher in the control group compared to the stud
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Jardé, T., F. Caldefie-Chézet, N. Goncalves-Mendes, et al. "Involvement of adiponectin and leptin in breast cancer: clinical and in vitro studies." Endocrine-Related Cancer 16, no. 4 (2009): 1197–210. http://dx.doi.org/10.1677/erc-09-0043.

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Obesity is a risk factor for breast cancer development. A recent hypothesis suggests that the adipokines, adiponectin and leptin, are involved in breast cancer development. This prompted us to investigate the role of adiponectin and leptin in mammary carcinogenesis. Adiponectin receptors (AdipoR1 and AdipoR2) and leptin receptor (Ob-Rt, representing all the isoforms of Ob-R) proteins were detected by immunohistochemistry in in situ ductal carcinoma, invasive ductal malignancy, and healthy adjacent tissue. In addition, mRNA expression of adiponectin, AdipoR1, AdipoR2, leptin, Ob-Rt, and Ob-Rl (
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Mi, Jie, Mercedes Nancy Munkonda, Ming Li, et al. "Adiponectin and Leptin Metabolic Biomarkers in Chinese Children and Adolescents." Journal of Obesity 2010 (2010): 1–10. http://dx.doi.org/10.1155/2010/892081.

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Objective. To evaluate leptin and adiponectin as biomarkers of metabolic syndrome (MS) risk factors even in nonobese children/adolescents.Methods. Serum leptin, adiponectin, leptin:adiponectin ratio, lipids, glucose, and insulin concentrations as well as body size parameters and pubertal development were evaluated in a large population of Chinese children/adolescents (n=3505, 6–18 years, 1722 girls and 1783 boys).Results. Leptin concentration increased while adiponectin decreased with obesity, both were influenced by pubertal development. Central obesity had an additive effect on leptin levels
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K, Selthofer-Relatić, Radić R, Stupin A, et al. "Leptin/adiponectin ratio in overweight patients – gender differences." Diabetes and Vascular Disease Research 15, no. 3 (2018): 260–62. http://dx.doi.org/10.1177/1479164117752491.

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Objective: Obesity-related atherosclerosis is a systemic disease with a background connected to multiple metabolic-neurohumoral pathways. The leptin/adiponectin ratio has been suggested as an atherosclerotic marker in obese patients. The aim of this study was to assess (1) the significance of the L/A ratio in overweight subjects, (2) the relation with anthropometric/metabolic parameters and (3) gender difference. Method: The study included 80 adult males and females, overweight, non-diabetic patients. Biochemical blood analysis and anthropometric and cardiovascular measurements were performed.
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Ambarwati, Ria, Damai Santosa, Eko Adhi Pangarsa, et al. "High Leptin and Low Adiponectin Levels in The Metabolic Syndrome Patients with Malignancy." Indonesian Biomedical Journal 15, no. 5 (2023): 297–303. http://dx.doi.org/10.18585/inabj.v15i5.2567.

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BACKGROUND: Metabolic syndrome (MetS), which is characterized by insulin resistance, adipocyte accumulation, and obesity, has been linked to malignancy development. Both leptin, an adipose tissue-produced cytokine-like hormone, and adiponectin, a hormone secreted by adipose tissue, play roles in the progression of MetS. However, the presence of leptin and adiponectin is also assumed to be associated with cancer proliferation. Therefore, it is necessary to investigate the profile of leptin and adiponectin levels in MetS patients with malignancy and non-malignancy.METHODS: This was a cross-secti
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Mednova, Irina A., Anastasiia S. Boiko, Elena G. Kornetova, et al. "Adipocytokines and Metabolic Syndrome in Patients with Schizophrenia." Metabolites 10, no. 10 (2020): 410. http://dx.doi.org/10.3390/metabo10100410.

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The adipokines leptin, adiponectin, tumor necrosis factor-alpha (TNF-α), and interleukin 6 (IL-6) might be associated with metabolic syndrome (MetS) in patients with schizophrenia. In the present study, we attempted to confirm the results of previous reports and assessed their MetS-related correlation with body fat composition and biochemical parameters. We measured in 46 patients with schizophrenia and MetS serum levels of adiponectin insulin, leptin, TNF-α and IL-6 and compared these levels to those of patients with schizophrenia without MetS. The MetS patients had significantly increased le
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Vega, Gloria Lena, and Scott M. Grundy. "Metabolic Risk Susceptibility in Men Is Partially Related to Adiponectin/Leptin Ratio." Journal of Obesity 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/409679.

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Background. High adiponectin/leptin ratio may be protective from metabolic risks imparted by high triglyceride, low HDL, and insulin resistance.Methods. This cross-sectional study examines plasma adipokine levels in 428 adult men who were subgrouped according to low (<6.5 μg/mL)and high (≥6.5 μg/mL)adiponectin levels or a low or high ratio of adiponectin/leptin.Results. Men with high adiponectin/leptin ratio had lower plasma triglyceride and higher HDL cholesterol than those with low ratio. Similarly, those with high adiponectin/leptin ratio had lower TG/HDL cholesterol ratio and HOMA2-IR t
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Tonelli, Adriano R., Wassim H. Fares, Wael Dakkak, Youlan Rao, Xuan Zhou, and Raed A. Dweik. "Do single or sequential measurements of leptin and adiponectin in plasma have prognostic value in pulmonary arterial hypertension?" Pulmonary Circulation 7, no. 3 (2017): 727–29. http://dx.doi.org/10.1177/2045893217717219.

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Leptin (a neuroendocrine peptide that enhances metabolism and acts on the hypothalamus to suppress appetite) and adiponectin (a protein that has insulin-sensitizing, anti-inflammatory, and antiproliferative properties) are involved in the pathobiology of pulmonary arterial hypertension (PAH). We hypothesized that plasma leptin and adiponectin as well as the leptin/adiponectin ratio are abnormal in PAH patients and their levels track with disease severity and functional changes during follow-up. We tested this hypothesis in a cohort of patients included in the 16-week, international, multicente
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Matovic, Sara, Christoph Rummel, Elena Neumann, Jennifer McGrath, and Jean-Philippe Gouin. "Adverse Childhood Experiences Influence Longitudinal Changes in Leptin But Not Adiponectin." Biopsychosocial Science and Medicine 87, no. 2 (2025): 118–28. https://doi.org/10.1097/psy.0000000000001366.

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Objective Adverse childhood experiences (ACEs) are associated with a greater risk of obesity and cardiometabolic disease. Adipokines, including leptin and adiponectin, play vital roles in biological processes linked to obesity and cardiometabolic risk. The adiponectin/leptin ratio may represent a marker of impaired hormonal regulation of adipose tissue. Prior cross-sectional studies suggest patterns of higher plasma leptin and lower adiponectin among adults who have experienced ACEs. This study addresses whether ACEs influence longitudinal changes in leptin, adiponectin, and the adiponectin/le
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Dissertations / Theses on the topic "Adiponectin/leptin"

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Ahire, Shwetal. "Maternal adiposity and plasma concentrations of leptin and adiponectin." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1250701408.

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Ahire, Shwetal V. "Maternal adiposity and the plasma concentration of leptin and adiponectin." Cincinnati, Ohio : University of Cincinnati, 2009. http://rave.ohiolink.edu/etdc/view.cgi?acc_num=ucin1250701408.

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Thesis (M.S.)--University of Cincinnati, 2009.<br>Advisor: Debra Krummel. Title from electronic thesis title page (viewed Oct. 20, 2009). Includes abstract. Keywords: pregnancy; skinfold; leptin; adiponectin; obesity. Includes bibliographical references.
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McMath, Arden Lee. "Associations Between Physical Activity Level and Adiponectin/Leptin Ratios in Older Adults." Miami University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=miami1556816283317575.

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Rausch, Jamie Ann. "Secondary Data Analysis Investigating Effects of Marine Omega-3 Fatty Acidson Circulating Levels of Leptin and Adiponectin in Older Adultswith Chronic Venous Leg Ulcers." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu158652907707218.

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Pratap, Anishchal Anshil. "Analysis of adiponectin, leptin and their receptor expression in the 5XFAD mouse model of Alzheimer’s disease." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/24135.

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Alzheimer’s disease (AD) is a neurodegenerative disorder that primarily affects individuals over 65 years of age. Pathological hallmarks of the disease include amyloid plaques and neurofibrillary tangles. Individuals with metabolic syndromes such as obesity and type-2 diabetes share similar pathologies with AD patients including insulin resistance, cortical atrophy and neuroinflammation. Adipocyte-derived leptin and adiponectin regulates metabolism, energy expenditure and satiety via their receptors, LepR, AdipoR1 and AdipoR2, respectively. Impaired leptin and adiponectin signalling causes met
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Barsnick, Rosa. "Hormones of Energy Metabolism in Critically Ill Foals: Insulin, Glucagon, Leptin, Adiponectin, Ghrelin and Growth Hormone." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1275523617.

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Jacobson, Sofie. "Severe sepsis : epidemiology and sex-related differences in inflammatory markers." Doctoral thesis, Umeå universitet, Anestesiologi och intensivvård, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-96214.

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Background.  Sepsis is a syndrome associated with high mortality rates, substantial morbidity and high costs of care. The incidents of sepsis is reported to be high and controversy exists whether gender affect severity or outcome. Little is known about factors determining suscepti­bility for developing the syndrome and severity of the syndrome once developed. Early detection and adequate antibiotic administration are the mainstay of treatment and means to identify patients with particular high risk of adverse outcome are desirable. There are data to suggest that the course of sepsis and outcom
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Dinca, Madalina, Maria-Corina Serban, Amirhossein Sahebkar, et al. "Does vitamin D supplementation alter plasma adipokines concentrations? A systematic review and meta-analysis of randomized controlled trials." Elsevier B.V, 2016. http://hdl.handle.net/10757/605887.

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We aimed to elucidate the role of vitamin D supplementation on adipokines through a systematic review and a meta-analysis of randomized placebo-controlled trials (RCTs). The search included PUBMED, Scopus, Web of Science and Google Scholar through July 1st, 2015. Finally we identified 9 RCTs and 484 participants. Meta-analysis of data from 7 studies did not find a significant change in plasma adiponectin concentrations following vitamin D supplementation (mean difference [MD]: 4.45%, 95%CI: -3.04, 11.93, p=0.244; Q=2.18, I(2)=0%). In meta-regression, changes in plasma adiponectin concentration
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Nickisch, Sabine. "Glukosetoleranz 24 Stunden postpartal und deren Beziehung zu anthropometrischen Daten sowie Adipozytokinserumkonzentrationen." Doctoral thesis, Universitätsbibliothek Leipzig, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-101180.

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Während der Schwangerschaft vollziehen sich im Körper der Frau verschiedene Adaptionsmechanismen, um eine bestmögliche Versorgung für das heranwachsende Kind zu gewährleisten. Bei fortschreitender Gravidität entwickelt sich eine physiologische Insulinresistenz. Gelingt es den maternalen Betazellen des Pankreas‘ nicht, diese zu kompensieren, kann eine diabetische Stoffwechsellage bis hin zur Ausbildung eines Gestationsdiabetes (GDM) entstehen. Adipozytokine beeinflussen direkt lokale und periphere metabolische, endokrinologische sowie immunologische Prozesse. Inwieweit sie in der Gravidität ei
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Will, Katja [Verfasser]. "Untersuchungen zum Einfluss der Adipokine Adiponectin und Leptin auf das Wachstum porciner Skelettmuskelzellen in vitro / Katja Will." Greifswald : Universitätsbibliothek Greifswald, 2014. http://d-nb.info/1053684789/34.

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Books on the topic "Adiponectin/leptin"

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Neumann, Elena, Klaus Frommer, and Ulf Müller-Ladner. Acute-phase responses and adipocytokines. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0058.

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Adipokines, also called adipocytokines, are highly bioactive substances mainly expressed by adipose tissue. In addition to adipocytes, different cell types resident in various tissues produce adipokines under pathophysiological conditions. Adipokines include a growing number of pluripotent molecules such as adiponectin, resistin, leptin, and visfatin. Since distinct effects of adipokines on inflammation have been described, their influence on the (innate) immune system has been investigated in rheumatology, gastroenterology, and endocrinology. This review gives an overview on the current knowl
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Book chapters on the topic "Adiponectin/leptin"

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Engin, Atilla. "Adiponectin Resistance in Obesity: Adiponectin Leptin/Insulin Interaction." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-63657-8_15.

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Laron, Zvi, and Hannah Kanety. "Adiponectin and Leptin in Laron Syndrome." In Laron Syndrome - From Man to Mouse. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-11183-9_16.

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Yu, Jerry Zhong, Kamyar Kalantar-Zadeh, and Connie M. Rhee. "Adiponectin and Leptin in Kidney Disease Patients." In Endocrine Disorders in Kidney Disease. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-97765-2_20.

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Brakenhielm, Ebba, and Yihai Cao. "Leptin, Adiponectin, and Other Adipokines in Regulation of Adipose Tissue Angiogenesis." In Angiogenesis in Adipose Tissue. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-8069-3_10.

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Fantuzzi, Giamila. "Adipokines: Leptin and Adiponectin in the Regulation of Inflammatory and Immune Responses." In Adipose Tissue and Adipokines in Health and Disease. Humana Press, 2014. http://dx.doi.org/10.1007/978-1-62703-770-9_6.

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Lenz, Anne M., and Frank Diamond. "The Importance of the Adiponectin and Leptin Relationship in In Utero and Infant Growth." In Handbook of Growth and Growth Monitoring in Health and Disease. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-1795-9_169.

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Bronsky, J., and K. Mitrova. "Adiponectin, adipocyte fatty acid-binding protein and leptin in human breast milk and impact in the infant." In Handbook of dietary and nutritional aspects of human breast milk. Wageningen Academic Publishers, 2013. http://dx.doi.org/10.3920/978-90-8686-764-6_21.

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Tu, Hong. "Leptin/Adiponectin." In Handbook of Biologically Active Peptides. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-385095-9.00072-5.

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Gavrila, A., D. Barb, and C. S. Mantzoros. "Leptin, Adiponectin, Resistin, Ghrelin." In Encyclopedia of Stress. Elsevier, 2007. http://dx.doi.org/10.1016/b978-012373947-6.00543-2.

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GAVRILA, A., D. BARB, and C. MANTZOROS. "Leptin, Adiponectin, Resistin, Ghrelin." In Encyclopedia of Stress. Elsevier, 2007. http://dx.doi.org/10.1016/b978-012373947-6/00543-2.

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Conference papers on the topic "Adiponectin/leptin"

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Nicolaou, N., J. Joseph, and I. N. Bruce. "AB0277 Leptin and adiponectin levels in rheumatoid arthritis patients." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.1189.

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Kryfti, Maria, Vasilis Galenterides, Katerina Dimakou, Michail Toumbis, and Gourgoulianis Konstantinos. "Effects of smoking cessation on serum leptin and adiponectin levels." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa1883.

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Jeong, Y.-J., H.-Y. Jeong, J.-G. Bong, S.-H. Park, J.-H. Choi, and H.-K. Oh. "P4-09-17: Leptin and Adiponectin Expression in Breast Cancer." In Abstracts: Thirty-Fourth Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 6‐10, 2011; San Antonio, TX. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/0008-5472.sabcs11-p4-09-17.

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Andersson, Lars I., Anna James, Barbro Dahlen, Sven-Erik Dahlen, Apostolos Bossios, and On Behalf Of Bioair Consortium. "Oral steroids induce leptin and adiponectin in subjects with airway obstructive diseases." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa3346.

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Oliveira, E. S., F. M. Kattah, N. Figueiredo, et al. "Association of Adiponectin, Leptin, and Daytime Sleepiness in Women with Severe Obesity." In XIX Congresso Brasileiro do Sono. Thieme Revinter Publicações Ltda., 2023. http://dx.doi.org/10.1055/s-0043-1770259.

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Yabushita, Hiromitsu, Keita Iwasaki, Taiki Ueno, and Akihiko Wakatsuki. "Abstract 4738: Clinicopathological roles of adiponectin receptor and leptin receptor in endometrial carcinoma." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4738.

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Azrad, Maria, Barbara A. Gower, Gary R. Hunter, and Tim R. Nagy. "Abstract B81: Racial differences in serum adiponectin and leptin before and after weight loss." In Abstracts: AACR International Conference on Frontiers in Cancer Prevention Research‐‐ Nov 7-10, 2010; Philadelphia, PA. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1940-6207.prev-10-b81.

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Howell, DL, NL Lugogo, S. Degan, et al. "Leptin Levels and Adiponectin Receptor Expression Are Increased in the Airways of Obese Asthmatics." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a2515.

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Galiutina, O., S. Shevchuk, Y. Seheda, and I. Kuvikova. "AB0130 Serum leptin and adiponectin levels in rheumatoid arthritis patients, their association with inflammatory process." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.5343.

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Ashktorab, Hassan, Akbar Soleimani, Alexandra Nichols та ін. "Abstract 3130: Adiponectin, Leptin, IGF1 and TNFα serum biomarker as noninvasive diagnosis of colon adenoma". У Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-3130.

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Reports on the topic "Adiponectin/leptin"

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Yuan, Qihang. Association of circulating leptin level, adiponectin level and risk of pancreatic cancer: a combination of traditional and dose-response meta-analysis. INPLASY - International Platform of Registered Systematic Review Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.4.0138.

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