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Relevant bibliographies by topics / Adjuvant de Freund

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Academic literature on the topic 'Adjuvant de Freund'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "Adjuvant de Freund"

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Near, Karen A., Anthony W. Stowers, Dragana Jankovic, and David C. Kaslow. "Improved Immunogenicity and Efficacy of the Recombinant 19-Kilodalton Merozoite Surface Protein 1 by the Addition of Oligodeoxynucleotide and Aluminum Hydroxide Gel in a Murine Malaria Vaccine Model." Infection and Immunity 70, no. 2 (2002): 692–701. http://dx.doi.org/10.1128/iai.70.2.692-701.2002.

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ABSTRACT Vaccination of mice with yeast-secreted Plasmodium yoelii-derived 19-kilodalton merozoite surface protein 1 (yMSP119) has been shown to afford protection from challenge with a lethal strain of P. yoelii. Sterile immunity can be achieved when MSP119 is emulsified in Freund adjuvant but not when it is adsorbed to aluminum hydroxide gel (alum). Because complete Freund adjuvant is not an acceptable adjuvant for use in humans, alternative adjuvants must be identified for formulating MSP119 as a vaccine for use in humans. To determine whether oligodeoxynucleotides with CpG motifs (ODN), rep

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Gaspar, Michael P., Genevieve Landes, Farinaz Safavi, and A. Lee Osterman. "Accidental Injection of Freund Complete Adjuvant With Mycobacterium Tuberculosis." Journal of Hand Surgery 43, no. 9 (2018): 873.e1–873.e4. http://dx.doi.org/10.1016/j.jhsa.2018.02.008.

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Foss, Dennis L., and Michael P. Murtaugh. "Mechanisms of vaccine adjuvanticity at mucosal surfaces." Animal Health Research Reviews 1, no. 1 (2000): 3–24. http://dx.doi.org/10.1017/s1466252300000025.

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AbstractThe vast majority of pathogens invade via mucosal surfaces, including those of the intestine. Vaccination directly on these surfaces may induce local protective immunity and prevent infection and disease. Although vaccine delivery to the gut mucosa is fraught with obstacles, immunization can be enhanced using adjuvants with properties specific to intestinal immunity. In this review, we present three general mechanisms of vaccine adjuvant function as originally described by Freund, and we discuss these principles with respect to intestinal adjuvants in general and to the prototypical mu

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Kumar, Vikas, F. A. Al-Abbasi, Amita Verma, Mohd Mujeeb та Firoz Anwar. "Umbelliferone β-d-galactopyranoside exerts an anti-inflammatory effect by attenuating COX-1 and COX-2". Toxicology Research 4, № 4 (2015): 1072–84. http://dx.doi.org/10.1039/c5tx00095e.

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Umbelliferone β-d-galactopyranoside (UFG) is a coumarin found in many plants. This study examines the anti-inflammatory potential of UFG on chronic inflammation induced by Complete Freund Adjuvant (CFA) in experimental rats.

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Shakya, Akhilesh Kumar, Ashok Kumar, and Kutty Selva Nandakumar. "Adjuvant properties of a biocompatible thermo-responsive polymer of N -isopropylacrylamide in autoimmunity and arthritis." Journal of The Royal Society Interface 8, no. 65 (2011): 1748–59. http://dx.doi.org/10.1098/rsif.2011.0114.

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To evaluate the thermo-responsive poly( N -isopropylacrylamide) (PNiPAAm) polymer as an adjuvant, we synthesized PNiPAAm through free radical polymerization and characterized it both in vitro and in vivo . The polymer when mixed with collagen type II (CII) induced antigen-specific autoimmunity and arthritis. Mice immunized with PNiPAAm–CII developed significant levels of CII-specific IgG response comprising major IgG subclasses. Antigen-specific cellular recall response was also enhanced in these mice, while negligible level of IFN-γ was detected in splenocyte cultures, in vitro . PNiPAAm–CII-

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STRASSBURGER, D., Y. IRLIN, H. CARP, et al. "Immune Features in Complete Freund Adjuvant-Treated CBA/J Mouse Model." American Journal of Reproductive Immunology 28, no. 3-4 (1992): 277–80. http://dx.doi.org/10.1111/j.1600-0897.1992.tb00814.x.

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Carpentier, A. F., T. Tran, F. Sejalon, et al. "The adjuvant effect of melanin is superior to Incomplete Freund adjuvant in a tumor subunit vaccine model." European Journal of Cancer 92 (March 2018): S2—S3. http://dx.doi.org/10.1016/j.ejca.2018.01.008.

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van Ommen, R., A. E. C. M. Vredendaal, M. de Gooyer, A. van Oudenaren та H. F. J. Savelkoul. "The Effect of IFN-γ, Alum and Complete Freund Adjuvant on TNP-KLH Induced Ig.G1, IgE and IgG2aResponses in Mice". Mediators of Inflammation 3, № 5 (1994): 387–92. http://dx.doi.org/10.1155/s0962935194000542.

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Adjuvants are considered to play an important role in directing the isotype and amount of antibodies produced upon immunization by conducting the development of either Th-1 or Th-2 cells upon T-cell stimulation. This is based on the different cytokine production patterns that were observed afterin vitroresttmulation of T cells isolated from mice immunized with antigen either adsorbed on alum or emulsified in complete Freund adjuvant (CFA). However, other studies suggest that primarily the type of antigen determines which isotypes are produced and to what extent. In these studies, however, IgE

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Stanislas-Leguern, Giséle, Roland Masse, Francis Jaubert, Jacques Chretien, and Gerard Huchon. "Pulmonary Gallium Uptake in Rats with Granulomatosis Induced by Complete Freund Adjuvant." Experimental Lung Research 14, no. 4 (1988): 445–58. http://dx.doi.org/10.3109/01902148809087820.

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Rajkapoor, B., V. Ravichandran ., M. Gobinath ., et al. "Effect of Bauhinia variegata on Complete Freund`s Adjuvant Induced Arthritis in Rats." Journal of Pharmacology and Toxicology 2, no. 5 (2007): 465–72. http://dx.doi.org/10.3923/jpt.2007.465.472.

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Dissertations / Theses on the topic "Adjuvant de Freund"

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Boivin, Sophie. "Modèle animal de sarcoïdose pulmonaire chez le rat par l'adjuvant de Freund complet : analyses de paramètres de l'inflammation et de l'efficacité d'un agoniste nicotinique comme thérapeutique." Thesis, Université Laval, 2007. http://www.theses.ulaval.ca/2007/24264/24264.pdf.

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Gomes, Raquel Pinheiro. "Atividade física no tratamento de artrite induzida por adjuvante de Freund : efeitos na nocicepção, edema e migração celular." Universidade do Estado de Santa Catarina, 2008. http://tede.udesc.br/handle/handle/382.

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Made available in DSpace on 2016-12-06T17:07:14Z (GMT). No. of bitstreams: 1 raquel.pdf: 914060 bytes, checksum: a82d971c1700ac78e8cc69f342332599 (MD5) Previous issue date: 2008-03-06<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Physical activity is thought to be beneficial to arthritis, delaying disability and/or improving joint function. The aim of the present study was to evaluate the effects of exercise on nociception, edema and cell migration in two groups of rats with CFA-induced arthritis, as well as verify whether the possible endogenous liberation of corticoids

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Cruz, Timilly Mayra Martins da. "Avalia??o dos efeitos anti-inflamat?rio e antiedematog?nico do gel Oxyflower? em modelo de edema de pata em ratos." UFVJM, 2017. http://acervo.ufvjm.edu.br/jspui/handle/1/1723.

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?rea de concentra??o: Cl?nica Odontol?gica.<br>Linha de pesquisa: Les?es inflamat?rias, c?sticas e neopl?sicas da cavidade bucal.<br>Na Folha de Rosto e Ficha Catalogr?fica da obra consta o t?tulo: "Avalia??o dos efeitos anti-inflamat?rio e antiedematog?nico do gel Oxyflower? em modelo de edema de pata induzido por adjuvante completo de Freund em ratos".<br>Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2018-05-22T17:57:16Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) timilliy_mayra_martins_cruz.pdf: 1084452 bytes, checksum:

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Oliveira, Patricia Gnieslaw de. "Efeito da administração do antagonista do receptor da bombesina/peptídeo liberador da gastrina RC-3095 na artrite induzida por CFA em ratos wistar." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/12628.

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O peptídeo liberador da gastrina (GRP), homólogo mamífero da bombesina (BN), é um neuropeptídeo com múltiplas ações biológicas, incluindo um importante papel na regulação da resposta imunológica e inflamatória. Está presente em altas concentrações no líquido sinovial de pacientes com artrite reumatóide (AR), paralelamente com os níveis de interleucina-6 (IL-6) e fator de necrose tumoral (TNF). RC-3095 é um antagonista sintético do receptor da BN/GRP que demonstrou modular a liberação de citocinas pró-inflamatórias (TNF e IL-1 ) e diminuir o infiltrado inflamatório em modelos experimentais de s

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Dubois, Dave. "Rôle de la substance P dans la régulation du récepteur opioïdergique delta." Mémoire, Université de Sherbrooke, 2010. http://savoirs.usherbrooke.ca/handle/11143/4076.

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À ce jour, les analgésiques de choix dans le traitement de la douleur sont toujours les composés opioïdergiques agissant sur le récepteur mu (MOPR), comme par exemple la morphine. Étant donné les effets secondaires indésirables observés avec ces agonistes, des alternatives ont été envisagées pour traiter la douleur adéquatement tout en réduisant les effets indésirables. Un rôle pour le récepteur opioïdergique delta (DOPR) a été proposé, car son activation engendre moins d'effets secondaires que MOPR. Cependant, la faible efficacité analgésique de ses agonistes limite son utilisation clinique.

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Philippe, Lionel. "Rôle de la substance P dans la régulation de l'anabolisme du cartilage : application aux antagonistes du recepteur NK1." Nancy 1, 1998. http://www.theses.fr/1998NAN10360.

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Murayama, Rafael Akira [UNESP]. "Contribuição ao estudo da osteoartrite secundária da articulação temporomandibular: estudo clínico - radiográfico retrospectivo em pacientes e modelo experimental em suínos." Universidade Estadual Paulista (UNESP), 2003. http://hdl.handle.net/11449/108381.

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Made available in DSpace on 2014-08-13T14:50:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2003Bitstream added on 2014-08-13T18:01:19Z : No. of bitstreams: 1 000188621.pdf: 2677751 bytes, checksum: 7dd7595889c35d6fe5c8b3e2e02a8999 (MD5)

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Silva, Morgana Duarte da. "Estudos comportamentais e farmacológicos com a diacereína no modelo de monoartrite induzida por adjuvante completo de freund (CFA) em ratos." Florianópolis, SC, 2009. http://repositorio.ufsc.br/xmlui/handle/123456789/92893.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.<br>Made available in DSpace on 2012-10-24T13:37:51Z (GMT). No. of bitstreams: 1 265366.pdf: 2761734 bytes, checksum: 0034f6e133cb9020706afbce0471d535 (MD5)<br>Osteoarthritis (OA) is the most prevalent form of rheumatic disease which affects joints like the knee, with pain as one of the most frequent symptoms among patients. Traditionally, drugs used for treatment of OA do not reduce joint damage, and have several side effects. A drug studied for this purpo

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Menezes, Raquel Rezende. "Monoartrite induzida por adjuvante completo de Freund em ratos Holtzman e avaliação dos efeitos induzidos pelo tratamento crônico com tiamina ou riboflavina." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/EMCO-9KKPMZ.

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Preclinical models of rheumatoid arthritis (RA) in rodents have been widely used to investigate the disease mechanisms and also to screen new drugs. Similarities with the human disease and predictive value for efficacy and safety are important criteria to choose a preclinical model of RA. Arthritis induced by adjuvant in rats is a preclinical model of RA with a well established predictive value for efficacy of antiarthritic drugs. Two injections of complete Freund adjuvante (CFA; Mycobacterium tuberculosis, 1 mg/mL) in the first day (one intradermal injection of 100 ìL into the tail base and o

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Santos, Daniella Soares dos. "Avaliação do efeito anti-inflamatório do toque terapêutico no modelo experimental de edema de pata induzido por adjuvante completo de Freund em camundongos." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/83/83131/tde-18072011-132224/.

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A dor é um dos sintomas que mais comprometem a produtividade, o bem estar e a qualidade de vida das pessoas, sobretudo dos idosos. Com o crescimento da utilização de Terapias Complementares para o seu tratamento surge a necessidade da realização de pesquisas que forneçam evidências sobre sua indicação e efetividade. Considerando a ampla utilização do Toque Terapêutico (TT) no tratamento complementar da dor decorrente de diversas condições clínicas e as críticas metodológicas aos resultados encontrados pelos autores, esta pesquisa buscou responder ao seguinte questionamento: Quais os efeitos do

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Book chapters on the topic "Adjuvant de Freund"

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White, R. G. "Immunopotentiation by Mycobacteria in Complete Freund-Type Adjuvant as the Failure of Normal Immunological Homeostasis." In Ciba Foundation Symposium 18 - Immunopotentiation. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470720011.ch4.

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Grubhofer, N. "Von Freunds Adjuvant zu Gerbu Vaccine Adjuvant." In Ersatz- und Ergänzungsmethoden zu Tierversuchen. Springer Vienna, 2000. http://dx.doi.org/10.1007/978-3-7091-6760-1_76.

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Leenaars, M., C. F. M. Hendriksen, M. A. Koedam, and E. Claassen. "Comparison of alternatives to Freund’s Complete Adjuvant." In Ersatz- und Ergänzungsmethoden zu Tierversuchen. Springer Vienna, 1997. http://dx.doi.org/10.1007/978-3-7091-6833-2_30.

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Shaha, C., S. Kaul, M. Kini, et al. "Immunization Against LHRH Without the Use of Freund’s Complete Adjuvant." In Immunological Approaches to Contraception and Promotion of Fertility. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5140-5_17.

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Barlas, A., H. Okamoto, and L. M. Greenbaum. "Increased Plasma Level of T-Kininogen in Rats Treated with Freund’s Adjuvant." In Kinins IV. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5143-6_9.

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Stewart-Tull, Duncan E. S. "Freund’s Complete and Incomplete Adjuvants, Preparation, and Quality Control Standards for Experimental Laboratory Animals Use." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-585-9_5.

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Semenenya, I. N., A. V. Gourine, and V. N. Gourine. "Prolonged “Slight” Fever in Rats Induced by Administration of Freund’s Complete Adjuvant: Effects of Indomethacin and NO-Related Drugs." In Thermal Balance in Health and Disease. Birkhäuser Basel, 1994. http://dx.doi.org/10.1007/978-3-0348-7429-8_53.

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Schwarzkopf, C., and B. Thiele. "Freund’s komplettes Adjuvans und mögliche Alternativen zur Gewinnung von IgY: Immunisierungsschemata, Titerentwicklung, Affinitätsreifung und biologische (Un-)Verträglichkeit." In Ersatz- und Ergänzungsmethoden zu Tierversuchen. Springer Vienna, 1997. http://dx.doi.org/10.1007/978-3-7091-6833-2_33.

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"Freund’s Complete Adjuvant." In Encyclopedia of Pain. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-28753-4_200832.

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"Complete Freund’s Adjuvant." In Encyclopedia of Pain. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-28753-4_200428.

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Conference papers on the topic "Adjuvant de Freund"

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Nasra, Julie, Kate L. Tomlinson, Matthew Catley, et al. "Development Of a Murine Model Of Lung Inflammation And Airway Hyperresponsiveness Driven By House Dust Mite In Complete Freund’s Adjuvant." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2842.

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Wernet, P., M. Haurand, W. Nüsing, E. M. Schneider, K. Jaschonek, and V. Ullrich. "Production and characterization of a murine monoclonal antibody against human thromboxane synthetase." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643382.

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Eicosanoids appear to have an important role in the actual momentary regulation of tissue blood flow. The function of constricting blood vessels by affecting the vascular tone has been assigned to thromboxane. Thromboxane synthetase, the enzyme responsible for the conversion of Prostaglandin-H2 into thromboxane A2, has been shown to be present in platelets, lung fibroblasts and the brain. Recently, thromboxane synthetase has been totally purified. The enzyme isolated from platelets appears to have a molecular weight of 58,800 Dalton and to belong to the group of cytochrome P450 proteins. In or

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