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1

Stegmann, Hartmut B., Klaus Stolze, and Klaus Scheffler. "ESR-und ENDOR-Untersuchungen der Autoxidationsprodukte des Adrenalons und analoger Verbindungen / ESR and ENDOR Investigations of the Autoxidation Products of Adrenalone and Related Compounds." Zeitschrift für Naturforschung B 41, no. 6 (1986): 776–80. http://dx.doi.org/10.1515/znb-1986-0617.

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Abstract The signs of the proton coupling constants of adrenalone semiquinone and related compounds were determined by ENDOR and TRIPLE resonance studies, thereby verifying the increment system described in our previous paper [2], Comparison of the spin-distribution of several substituted acylcatechols showed the conformational influence on the coupling constants due to mesomeric interaction of the carbonyl group with the aromatic π-system. Adrenalone and other N -monosubstituted catecholamines showed rather stable secondary radi­cals after the decay of the primary semiquinone radical. They we
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2

Jahandari, Shokoofe, Mohammad Ali Taher, and Hassan Karimi-Maleh. "A first adrenalone electrochemical sensor using a gold-nanoparticle/poly(pyrrole) composite-modified graphite electrode." Analytical Methods 11, no. 20 (2019): 2658–62. http://dx.doi.org/10.1039/c8ay02765j.

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In this study, a pencil graphite electrode (PGE) modified with a composite of polypyrrole and Au nanoparticles (Au-NPs/PP/PGE) was developed and evaluated as a novel electrochemical sensor for the determination of adrenalone for the first time.
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3

Sârbu, Costel, and Dorina Casoni. "Comprehensive evaluation of biogenic amines and related drugs’ antiradical activity using reactive 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical." Open Chemistry 11, no. 5 (2013): 679–88. http://dx.doi.org/10.2478/s11532-013-0210-y.

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AbstractA comprehensive study of biogenic amines and related drugs as free radical scavengers and potential antioxidants was carried out using the stable free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH·). The results of the effect of test duration and the relative concentration on the ability of the compounds to scavenge the DPPH· were investigated and discussed. The antiradical activity of amines was compared with the activity of some reference antioxidants (phenols, phenolic acids, flavonols and other antioxidants). Some particular insights related to the mechanism of reactivity toward the
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4

He, Zhixian, Jinyue Wang, Xing Wang, and Yv Dong. "The Study of the Transport Mechanism of Isorhynchophylline in Liver." Evidence-Based Complementary and Alternative Medicine 2022 (January 19, 2022): 1–8. http://dx.doi.org/10.1155/2022/3867323.

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To investigate the transport mechanism of isorhynchophylline (IRN) by using the specific inhibitors of organic cation transporters (OCTs) and organic anion transporting polypeptides (OATPs) and attempt illustrate the metabolic mechanism of IRN in the liver. All animals were randomly divided into three groups: control group (only inject IRN), RIF group (inject IRN and rifampicin), and ADR group (inject IRN and adrenalone). The control group was injected with IRN via the caudal vein. The RIF group was injected with rifampicin (RIF) by gavage, and after 1 h, IRN was injected into the caudal vein.
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5

Kirchhoefer, Ross D., Gerard M. Sullivan, and James F. Allgire. "Analysis of USP Epinephrine Injections for Potency, Impurities, Degradation Products, and d-Enantiomer by Liquid Chromatography, Using Ultraviolet and Electrochemical Detectors." Journal of AOAC INTERNATIONAL 68, no. 2 (1985): 163–65. http://dx.doi.org/10.1093/jaoac/68.2.163.

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Abstract A liquid chromatographic (LC) method was adapted for the determination of epinephrine and related impurities in intravenous and cardiac injections; ultraviolet (UV) and electrochemical detectors (EC) were used in series. Epinephrine was determined and related impurities, i.e., adrenalone, epinephrine sulfonic acid, and norepinephrine, were detected directly in a small portion of the injection solution. Diastereoisomers of the epinephrine enantiomers were prepared by derivatization and determined by LC with a UV detector. The recovery of epinephrine added to epinephrine injection was 1
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6

Mohr, Siegfried, Gert Heller, Ulrich Timper, and Karl-Heinz Woller. "Neue Untersuchungen an Borsäureestern von Brenzcatechin und einiger Catecholamine in wäßriger Lösung und an Feststoffen / New Investigations of Boric Acid Esters of Catechole and of Some Catecholamines in Aqueous Solutions and on Solids." Zeitschrift für Naturforschung B 45, no. 3 (1990): 308–22. http://dx.doi.org/10.1515/znb-1990-0306.

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The orthoborate ion [B(OH)4]⁻ in aqueous solutions between pH 5 and 12 forms stable boric acid esters with catechole and the catecholamines DOPA, α-methyldopa, dopamine, noradrenaline, adrenaline, and adrenalone. The stoichiometries of the esters in solution, their dependence of pH value and concentration were evaluated by 11B NMR spectra and confirmed by Raman investigations in the catechole system. Additionally, Raman spectra and crystal structure investigations on solid crystalline esters confirm these results. The 1:1 esters show in the 11B NMR spectrum a chemical shift δ of around 8.1 ppm
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7

Pšeničny, Andreja. "Razvoj Vprašalnika sindroma adrenalne izgorelosti (SAI) in preverjanje izhodišča recipročnega modela izgorelosti." Psihološka obzorja 16, no. 2 (2007): 47–81. https://doi.org/10.20419/2007.16.225.

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V prispevku predstavljamo oblikovanje novega Vprašalnika sindroma adrenalne izgorelosti (SAI). Nastal je na osnovi Recipročnega modela izgorelosti s povezovanjem podatkov iz strokovnih virov ter raziskovalnega dela v okviru Inštituta za razvoj človeških virov iz Ljubljane. Oblikovali smo vprašalnik, ki razlikuje med posameznimi stopnjami izgorelosti in njihovimi značilnimi znaki. Cilj raziskave, ki smo jo s tem vprašalnikom in Vprašalnikom zadovoljenosti potreb izvedli na 225 osebah, je bilo: (i) preveriti razlike v stopnji izgorelosti med demografskimi skupinami, (ii) ugotoviti razlike v pris
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8

Kovalchuk, Y. P., O. O. Dovban, A. M. Kanga, and G. A. Ushakovа. "Short-term effect of adrenalin on S-100b and N-CAM level in the different rat brain areas." Visnyk of Dnipropetrovsk University. Biology, medicine 6, no. 2 (2015): 119–24. http://dx.doi.org/10.15421/021522.

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The level of adrenalin grows under stress conditions, sense of danger, anxiety, fear, trauma, burns and shock. In high concentrations adrenaline increases the speed of protein catabolism. Working through the circulatory system, adrenaline affects almost all the functions of organs, causing the body mobilization to counter stressful situations. Due to ELISA the astrocytes-specific protein (S-100b) and neural cell adhesion molecule (N-CAM) were studied. S-100b is produced mainly by astrocytes іn the brain and depending on the concentration it causes trophic or toxic effect on the neurons and gli
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9

a, Isehunwa, Grace Olufunmilayo, Shittu b, et al. "THE ROLE OF ADRENERGIC RECEPTORS IN THE ACTION OF ADRENALINE ON PLASMA LACTATE, GLUCOSE, LIVER, AND SKELETAL MUSCLE GLYCOGEN IN THE COMMON AFRICAN TOAD BUFO REGULARIS." International Journal of Advanced Research 11, no. 01 (2023): 275–82. http://dx.doi.org/10.21474/ijar01/16017.

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In mammals, the roles of liver and skeletal muscle glycogen in adrenaline-induced hyperglycaemia are well known. However, in amphibians, there is limited information on the relative contribution of liver and skeletal muscle glycogen in adrenaline-induced hyperglycaemia. This study investigated the effects of adrenaline on blood glucose, plasma lactate, liverand skeletal muscle glycogen and the role of adrenergic receptors in the common African toad, bufo regularis. One hundred and twenty-five adult common African toads (70-100g) of both sexes were randomly collected and used in the study.Blood
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10

Gołaszewska, Agata. "Znaczenie adrenaliny w mechanizmie aktywacji ludzkich płytek krwi." Acta Haematologica Polonica 50, no. 2 (2019): 65–73. http://dx.doi.org/10.2478/ahp-2019-0012.

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StreszczenieZakrzepy i zatory stanowią obecnie główną bezpośrednią przyczynę zgonów u hospitalizowanych pacjentów w krajach rozwiniętych. Szczególnie istotną rolę w procesie krzepnięcia, jak również w stanach patologicznej nadkrzepliwości, odgrywają płytki krwi. Jednym z fizjologicznych aktywatorów płytek krwi o stosunkowo mało poznanym mechanizmie działania jest adrenalina (epinefryna). Co istotne, warunki predysponujące do pojawienia się we krwi podwyższonego stężenia adrenaliny korelują ze zwiększonym ryzykiem epizodów zakrzepowych. Ludzkie płytki krwi posiadają w swej błonie plazmatycznej
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11

MUHAMMAD NOVID, MUHAMMAD NOVID, and Nanang Indardi. "PENGARUH PANDEMI COVID-19 TERHADAP JUMLAH PENGUNJUNG WAHANA PERMAINAN PACU ADRENALIN REGENTAR DI KAWASAN WISATA UMBUL SIDOMUKTI DI KABUPATEN SEMARANG TAHUN 2020." Journal of Sport Science and Fitness 9, no. 1 (2023): 1–10. http://dx.doi.org/10.15294/jssf.v9i1.59169.

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Covid-19 memberikan dampak yang besar terhadap sektor pariwisata, terutama olahraga rekreasi. Wahana permainan pacu adrenaline Ragentar di Kawasan wisata Umbul Sidomukti merasakan dampak menurunnya jumlah pengunjung di tahun 2020. Berdasarkan hasil analisis jumlah pengunjung ditahun 2019 masih relatif tinggi jika dibandingakan tahun 2020. Penelitian ini bertujuan untuk mengetahui pengaruh pandemi covid-19 terhadap jumlah pengunjung Wahana Permainan Pacu Adrenalin Ragentar. Jenis penelitian kuantitatif yaitu analisa data yang digunakan berdasarkan perhitungan statistik dengan pengumpulan, pengo
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12

Luck, MR, and M. Munker. "Beta adrenoceptors mediate the catecholamine-induced stimulation of oxytocin secretion from cultured bovine granulosa cells." Reproduction, Fertility and Development 3, no. 6 (1991): 715. http://dx.doi.org/10.1071/rd9910715.

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Bovine granulosa cells were treated in culture with alpha- and beta-adrenoceptor ligands to determine the receptor subtype mediating their response to catecholamines. The secretion of oxytocin by granulosa cells in serum-free medium was measured on the fourth day of culture (during the period of acquisition of a luteal phenotype). Cultures were performed in the presence of 0.5 mM ascorbic acid, which increased hormone output and potentiated the response to catecholamines. The effects of adrenaline and noradrenaline on oxytocin secretion were concentration-dependent; maximum stimulation was ove
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13

Kamaluddin, Azlan, Mohd Hashairi Fauzi, SA Syed Hussein, Hardawani Mohd Hussein, Fatahul Laham Mohamed, and Norzuraini Abu Bakar. "2 Handfuls of Medication in 2 Hours Just to Let Him Talk." Bangladesh Journal of Medical Science 13, no. 2 (2014): 209–11. http://dx.doi.org/10.3329/bjms.v13i2.16100.

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Repeated dose of adrenaline in anaphylaxis is limited evidence in clinical setting. Hence, the usage is depending on physician best interest and knowledge. We reported a case of repeated doses of adrenalin was given through nebulizer and intravenous in anaphylaxis. We believed the unusual circumstances of this case was likely to be repeated on some readers' clinical practice and this mode of treatment is an adjunct to consider in such cases especially in Emergency Department (ED). DOI: http://dx.doi.org/10.3329/bjms.v13i2.16100 Bangladesh Journal of Medical Science Vol.13(2) 2014 p.209-211
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14

Afshar, Safoora, Hassan Ali Zamani, and Hassan Karimi-Maleh. "NiO/SWCNTs coupled with an ionic liquid composite for amplified carbon paste electrode; A feasible approach for improving sensing ability of adrenalone and folic acid in dosage form." Journal of Pharmaceutical and Biomedical Analysis 188 (September 2020): 113393. http://dx.doi.org/10.1016/j.jpba.2020.113393.

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15

Bilovol, A. M., S. G. Tkachenko, and A. A. Berehova. "COMPARATIVE CHARACTERISTICS OF INDICATORS OF NEUROENDOCRINE REGULATION IN PATIENTS WITH LICHENOID DERMATOSES." Dermatology and Venerology, no. 1-2 (2022): 14–16. http://dx.doi.org/10.33743/2308-1066-2022-1-2-14-16.

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The aim is to study the indicators of neuroendocrine regulation in patients with chronic lichenoid dermatoses. Materials and methods. Studies of neuroendocrine system indicators were performed in two groups of patients: 1–60 patients with psoriasis, 2–56 patients with lichen planus, the control group consisted of 15 healthy individuals, whose indicators were considered normal. Determination of serotonin, histamine, histaminase, corticotropin, adrenaline in the serum of patients was performed by enzyme-linked immunosorbent assay. Results. There was a reliable increase in mean serum serotonin le
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16

Guha, Abhijit, Charles H. Tator, and Ian Piper. "Effect of a calcium channel blocker on posttraumatic spinal cord blood flow." Journal of Neurosurgery 66, no. 3 (1987): 423–30. http://dx.doi.org/10.3171/jns.1987.66.3.0423.

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✓ The normal rat spinal cord blood flow (SCBF) has been shown to increase after administration of nimodipine, a calcium channel blocker. The present study investigates the capability of nimodipine to improve SCBF, as measured by the hydrogen clearance technique, after a 53.0-gm clip compression injury to the T-1 segment of the rat spinal cord. The profound drop in mean systemic arterial blood pressure (MSAP) after cervical cord injury precluded any improvement in posttraumatic SCBF by nimodipine alone. Hence, in a randomized controlled study with five rats per group, pressor agents (whole bloo
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17

Kis, Erika. "A comparative study of adrenalin and fluocinolon induced oxidative stress in male wistar rats." Studia Universitatis Babeş-Bolyai Biologia 65, no. 2 (2020): 5–18. http://dx.doi.org/10.24193/subbbiol.2020.2.01.

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Hormone secretion by the hypothalamic-pituitary-adrenocortical (HPA) axis is modulated by multiple factors which include the circadian rhythm, various types of stressors and glucocorticoids. Treatment with synthetic glucocorticoids as e.g. dexamethasone or dermocorticosteroids and repeated immobilization stress, decreases the total body weight gain of animals by disturbing the HPA axis function and accelerating the catabolism of the organism. Synthetic glucocorticoids are widely used as anti-inflammatory and anti-allergic drugs. Neverteheless, their administration may cause side effects in the
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18

Baloch, Naseer Khan, Nusrat Jafri, and Ahmed Danyal. "ADRENALINE;." Professional Medical Journal 21, no. 06 (2014): 1157–60. http://dx.doi.org/10.29309/tpmj/2014.21.06.2163.

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There is no doubt that the effects of the catecholamines of the heart are mainly due to the stimulation of β-adrenoceptors but in the mid 1960’ s the first evidence was presented that a-adrenoceptors mediating positive inotrpoism exists also in the myocardium beside well established β -adrenoceptors. In our observation adrenaline shows a positive inotropic response. The response of adrenaline in presence of metoprolol (β1blocker) showed negative inotropic effect.
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19

Fessenden, Marissa. "Adrenaline." Scientific American 308, no. 4 (2013): 84. http://dx.doi.org/10.1038/scientificamerican0413-84c.

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20

Burki, Talha Khan. "Adrenaline." Lancet Diabetes & Endocrinology 1 (August 2013): s19. http://dx.doi.org/10.1016/s2213-8587(13)70023-8.

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21

Pouwels, Sjaak, Emschka Johannes, and Juan Pablo Scarano-Pereira. "Effects of Intravenous Versus Intraosseous Adrenalin Administration on Morbidity and Mortality After Out-of-Hospital Cardiac Arrest: A Systematic Review." Medicina 61, no. 4 (2025): 680. https://doi.org/10.3390/medicina61040680.

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Background and Objectives: Out-of-hospital cardiac arrest (OHCA) is a common manifestation of heart disease and a leading cause of death in western societies with an overall survival rate of 10%. Guidelines generally prefer the peripheral intravenous (IV) access as the first option for OHCA patients, leaving the intraosseous (IO) route for patients in which IV access is not feasible or unsuccessful. This systematic review will purely focus on the clinical differences between adrenaline administered via the IO route compared to the IV route and its effects on morbidity and mortality after OHCA.
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22

Braatvedt, G. D., M. D. Flynn, A. Stanners, M. Halliwell та R. J. M. Corrall. "Splanchnic blood flow in man: evidence for mediation via a β-adrenergic mechanism". Clinical Science 84, № 2 (1993): 201–7. http://dx.doi.org/10.1042/cs0840201.

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1. Superior mesenteric artery blood flow was examined by Doppler ultrasound in six male subjects aged 19–23 years during the infusion of saline (control), 10 and 40 ng of adrenaline min−1 kg−1 for 30 min, or propranolol and 10 ng of adrenaline min−1kg−1 for 30 min, on four separate occasions. 2. Adrenaline infusion resulted in significant peak mean (SEM) rises in circulating adrenaline concentrations during the infusion period only [control, 0.20 (0.05) nmol/l; 10 ng of adrenaline min−1 kg−1, 1.37 (0.29) nmol/l; 40 ng of adrenaline min−1kg−1, 3.73 (0.40) nmol/l; 10 ng of adrenaline min−1kg−1 a
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23

Meyerholz, H. H., A. Gardemann, and K. Jungermann. "Control of glycogenolysis and blood flow by arterial and portal adrenaline in perfused liver." Biochemical Journal 275, no. 3 (1991): 609–16. http://dx.doi.org/10.1042/bj2750609.

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In isolated liver from fed rats, simultaneously single-pass-perfused via both the hepatic artery (80 mmHg, 30-35% flow) and the portal vein (10 mmHg, 70-65% flow), adrenaline was infused either singly or jointly via the hepatic artery or the portal vein in the absence or presence of the alpha 1-blocker prazosin and the beta 2-blocker butoxamine. It was found that: (1) arterial adrenaline caused increases in glucose and lactate output which were slower in onset, smaller in peak height but longer in duration than did portal adrenaline; (2) arterial adrenaline elicited a much more pronounced decr
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24

García, M. C., and J. Escamilla-Sánchez. "Positive inotropic effect of adrenaline on potassium contractures in tonic skeletal muscle fibres of the frog." Canadian Journal of Physiology and Pharmacology 72, no. 12 (1994): 1580–85. http://dx.doi.org/10.1139/y94-227.

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K+ contractures were elicited in small bundles of tonic skeletal muscle fibres of the frog. Adrenaline (1 μM) increased the amplitude of K+ contractures in a [K+]o-dependent manner: maximal effects were produced between 20 and 60 mM [K+]o. In contrast, we found no effect of adrenaline on K+ contractures of twitch fibres. The potentiating effect of adrenaline depended on [Ca2+]o. Increasing [Ca2+]o from 1.8 to 10 mM doubled the positive inotropic effect of adrenaline. In a nominally Ca2+ free saline, adrenaline had no potentiating effect. The Ca2+ channel blockers nifedipine (20 μM) and Ni2+ (1
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Higuchi, Hitoshi, Akiko Yabuki, Minako Ishii-Maruhama, Yumiko Tomoyasu, Shigeru Maeda, and Takuya Miyawaki. "Hemodynamic Changes by Drug Interaction of Adrenaline With Chlorpromazine." Anesthesia Progress 61, no. 4 (2014): 150–54. http://dx.doi.org/10.2344/0003-3006-61.4.150.

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Abstract Adrenaline (epinephrine) is included in dental local anesthesia for the purpose of vasoconstriction. In Japan, adrenaline is contraindicated for use in patients receiving antipsychotic therapy, because the combination of adrenaline and an antipsychotic is considered to cause severe hypotension; however, there is insufficient evidence supporting this claim. The purpose of the present study was to clarify the changes in hemodynamics caused by drug interaction between adrenaline and an antipsychotic and to evaluate the safety of the combined use of adrenaline and an antipsychotic in an a
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26

Milena, Radaković, Đelić Ninoslav, Stevanović Jevrosima, et al. "The Investigation of DNA Damage Induced by Adrenaline in Human Lymphocytes in Vitro/Ispitivanja Oštećenja DNK Izazvanih Adrenalinom U Limfocitima Čoveka in Vitro." Acta Veterinaria 64, no. 3 (2014): 281–92. http://dx.doi.org/10.2478/acve-2014-0027.

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Abstract Adrenaline is a neurotransmitter and hormone that plays an important role in physiological regulatory mechanisms. The objective of this study was to assess primary DNA damage in isolated human lymphocytes exposed to adrenaline using the in vitro comet assay. Dose-response of human lymphocytes was determined at concentration range of adrenaline from 0.01 μM to 300 μM for various treatment times (1h, 2h, 4h and 24h). The obtained results showed that adrenaline induced DNA damage at concentration range from 5 μM to 300 μM after 1h, 2h and 4h of treatment. The slightest DNA damage was obs
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27

Bjerre-Bastos, J., C. Sejersen, H. B. Nielsen, et al. "AB0984 CHANGES IN PLASMA VOLUME WHEN MEASURING BIOCHEMICAL MARKERS OF JOINT TISSUE TURNOVER IN RELATION TO ACUTE PHYSICAL ACTIVITY." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1618.1–1618. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2774.

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BackgroundPhysical activity can induce acute changes in plasma volume (PV) and thereby influence concentration of plasma constituents, such as biochemical markers1,2. However, it remains undocumented to what extent PV changes occur during physical exercise in osteoarthritis (OA) patients.ObjectivesInvestigating the direct course and magnitude of PV changes during and after weight-bearing (WB) and non-weight-bearing (NWB) exercise, adrenaline-induced cardiovascular stress and resting in an OA population.MethodsData originates from the EFEX-OA-02 study (Reg. no.: NCT04542668), which explored bio
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Aziz, Bara’a Mahir, Islam Al-Talibi, Shalan Mufleh Darak, Ali Abdulmuttalib Mohammed, and Haitham Alnori. "Tranexamic acid versus adrenaline-soaked pledgets for the reduction of intraoperative bleeding in functional endoscopic sinus surgery." Polski Merkuriusz Lekarski 52, no. 1 (2024): 36–41. http://dx.doi.org/10.36740/merkur202401106.

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Aim: To examine the impact of locally applied tranexamic acid and adrenaline, separately and in combination, on intraoperative blood loss and surgical field quality during functional endoscopic sinus surgery. Materials and Methods: The study involved 40 patients with chronic rhinosinusitis. They were divided into two groups. Group I received adrenaline alone in one side and a mixture of adrenaline and tranexamic acid in the other side. Group II received adrenaline alone in one side and tranexamic acid in the otherside. Parameters like surgery time, blood loss, and surgical field quality were s
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Chethan, L., Kumar P. Harish, Ramesh Kumar Sharma, and Sandhya Yaddanapudi. "Comparison of blood loss at the donor site & Acute cardiovascular effects by using adrenaline infiltration and topical adrenaline during skin graft harvest." Journal of Clinical and Investigative Surgery 7, no. 1 (2022): 56–61. http://dx.doi.org/10.25083/2559.5555/7.1.10.

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Background. Burn surgery is associated with high blood loss to both the donor and recipient site. Although various techniques for reducing intraoperative blood loss have been described, topical adrenaline and adrenaline infiltration have significantly reduced blood loss. The present study compared blood loss to the donor site and acute cardiovascular effects (such as heart rate/ HR and blood pressure/ BP), by using adrenaline infiltration and topical adrenaline while harvesting the skin graft in the same patient, but in a different place. Materials and Methods. It is a prospective study that i
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Lalau Keraly, C., J. D. Vickers, R. L. Kinlough-Rathbone, and J. F. Mustard. "Involvement of phosphoinositide metabolism in potentiation by adrenaline of ADP-induced aggregation of rabbit platelets." Biochemical Journal 242, no. 3 (1987): 841–47. http://dx.doi.org/10.1042/bj2420841.

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Changes in phosphoinositide metabolism were examined in washed rabbit platelets stimulated with 0.5 microM-ADP, 50 microM-adrenaline, or ADP and adrenaline in combination. Adrenaline does not stimulate platelet aggregation when used alone, but does potentiate aggregation stimulated by ADP. In platelets prelabelled with [32P]Pi and [3H]glycerol, adrenaline was found to potentiate the ADP-induced changes in platelet phospholipids, causing larger increases in the amount and labelling of phosphatidylinositol 4-phosphate (PIP) and phosphatidic acid than was observed with ADP alone. The combination
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31

Eldadah, Basil A., Sandra L. Pechnik, Courtney S. Holmes, Jeffrey P. Moak, Ahmed M. Saleem, and David S. Goldstein. "Failure of propranolol to prevent tilt-evoked systemic vasodilatation, adrenaline release and neurocardiogenic syncope." Clinical Science 111, no. 3 (2006): 209–16. http://dx.doi.org/10.1042/cs20060017.

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In patients with neurocardiogenic syncope, head-up tilt often evokes acute loss of consciousness accompanied by vasodilatation, increased plasma adrenaline and systemic hypotension. Since hypotension increases adrenaline levels and adrenaline can produce skeletal muscle vasodilatation by activating β2 receptors, adrenaline might induce a positive feedback loop precipitating circulatory collapse. We hypothesized that propranolol, a non-selective β-blocker, would prevent adrenaline-induced vasodilatation and thereby prevent syncope. Eight subjects with recurrent neurocardiogenic syncope and prev
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32

Hellstrand, K., S. Hermodsson, and O. Strannegård. "Evidence for a beta-adrenoceptor-mediated regulation of human natural killer cells." Journal of Immunology 134, no. 6 (1985): 4095–99. http://dx.doi.org/10.4049/jimmunol.134.6.4095.

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Abstract Pretreatment of lymphocytes (16 hr, 37 degrees C) with adrenaline at final concentrations of 10(-7) to 10(-9) M, followed by removal of the drug, increased natural killer (NK) cell activity vs K562 leukemic cells in a 4-hr 51Cr-release assay. The most efficient concentration of adrenaline was 10(-8) M; mean increase of NK activity over base-line activity for all donors examined was 30%. However, the individual response to adrenaline pretreatment was variable; in some donors, the effect was equal to maximal interferon (IFN) stimulation. Effects of adrenaline pretreatment were consisten
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Thompson, Jane M., B. Gunnar Wallin, Gavin W. Lambert, Garry L. Jennings, and Murray D. Esler. "Human Muscle Sympathetic Activity and Cardiac Catecholamine Spillover: No Support for Augmented Sympathetic Noradrenaline Release by Adrenaline Co-Transmission." Clinical Science 94, no. 4 (1998): 383–93. http://dx.doi.org/10.1042/cs0940383.

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1. Evidence from animal studies indicates that circulating adrenaline may be taken up into sympathetic nerves, facilitating the release of noradrenaline. To test whether adrenaline acts as a co-transmitter in humans we studied eight healthy men (aged 19–23 years) during isometric handgrip before and after an adrenaline infusion (1–3 μg/min for > 30 rain). Sympathetic activity was assessed using radiotracer kinetic techniques to measure total and cardiac spillovers of noradrenaline and adrenaline, and microneurography to measure muscle sympathetic activity. 2. During the adrenaline infusion
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34

Rudenko, M. Y., I. А. Berseneva, M. P. Deberdeev, et al. "Adrenaline heart." CARDIOMETRY, no. 22 (May 25, 2022): 106–7. http://dx.doi.org/10.18137/cardiometry.2022.22.106107.

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The role of adrenaline in the body, especially in athletes, is considered. Special attention is paid to the cardiovascular system performance in conditions of the continuous release of adrenaline. The ECG shape and the possible therapy in case of adrenaline heart are discussed.
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35

Keohane, M., and S. R. Luney. "Adrenaline 0.5%?" Anaesthesia 56, no. 8 (2001): 799–820. http://dx.doi.org/10.1046/j.1365-2044.2001.02181-31.x.

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36

WEBSTER, N. R., and W. HINTON. "Topical adrenaline." Anaesthesia 41, no. 4 (1986): 435. http://dx.doi.org/10.1111/j.1365-2044.1986.tb13244.x.

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37

Gwinnutt, C. L., and W. D. Lord. "Nebulised adrenaline." Anaesthesia 42, no. 3 (1987): 320–21. http://dx.doi.org/10.1111/j.1365-2044.1987.tb03059.x.

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38

Choudhry, A. K. "Nebulised adrenaline." Anaesthesia 42, no. 3 (1987): 321–22. http://dx.doi.org/10.1111/j.1365-2044.1987.tb03060.x.

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Child, C. S. B. "Nebulised adrenaline." Anaesthesia 42, no. 3 (1987): 322. http://dx.doi.org/10.1111/j.1365-2044.1987.tb03061.x.

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40

Livesey, J. R., and W. F. de Mello. "Nebulized adrenaline." Journal of Laryngology & Otology 104, no. 10 (1990): 840. http://dx.doi.org/10.1017/s0022215100114069.

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41

Regent, Lynne, and Danielle Johnson. "Adrenaline autoinjectors." Clinical & Experimental Allergy 50, no. 6 (2020): 652–53. http://dx.doi.org/10.1111/cea.13615.

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42

Buchko, O., V. Havryliak, O. Yaremkevych, R. Konechna, and N. Ohorodnyk. "Metabolic processes in the organism of animals under the action of plant extract." Regulatory Mechanisms in Biosystems 10, no. 2 (2019): 149–58. http://dx.doi.org/10.15421/021922.

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The possibility of increasing metabolism and resistance in an organism of animals under the influence of biologically active substances of natural origin is considered in the paper. In the current study, we investigated the effect of 40% ethanolic extract of common nettle (Urtica dioica L.) on hematologic indexes (hemoglobin concentration, erythrocytes and leukocytes content), protein metabolism (total protein, aspartate aminotransferase (AST), alanine aminotransferase activities (ALT)), glutathione metabolism (peroxidase (GP), glutathione reductase (GR) and reduced glutathione content (GSH)),
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43

Górski, Jan, and Małgorzata Knapp. "Udział hormonów w regulacji metabolizmu substratów energetycznych w czasie wysiłku." Kosmos 69, no. 4 (2021): 765–75. http://dx.doi.org/10.36921/kos.2020_2716.

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Głównymi substratami energetycznymi w czasie wysiłku są glukoza i wolne kwasy tłuszczowe (FFA), zaś aminokwasy zużywane są tylko w niewielkim stopniu. W czasie wysiłku aktywowany jest proces rozkładu glikogenu w wątrobie i w pracujących mięśniach. Glikogenoliza w wątrobie aktywowana jest przez glukagon i adrenalinę, natomiast w kurczących się mięśniach przez jony wapnia. Adrenalina pełni rolę wspomagającą. Glukagon i kortyzol zwiększają proces glukoneogenezy w wątrobie. Głównym enzymem lipolitycznym jest lipaza triglicerydowa tłuszczowa (ATGL). Istniejące dane wskazują, że za aktywację tego en
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44

Indrasana, Praba. "POTENSI WISATA KINAHREJO YANG BERKELANJUTAN, Dusun Kinahrejo, Umbulharjo, Sleman, Yogyakarta." Jurnal Arsitektur KOMPOSISI 12, no. 1 (2018): 27. http://dx.doi.org/10.24002/jars.v12i1.1644.

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Abstract: Dusun Kinahrejo has diverse and interesting regional characteristics, with a dynamic regional order in the development of tourist areas. Kinahrejo hamlet is located in an area prone to eruption of Merapi, which is on the slopes of Mount Merapi Umbulharjo village, Cangkringan, Sleman. The declining interest of tourists during the visit in 2015 has an impact on the sustainability of the tourism potential and the economy of the people who rely heavily on the tourism sector. So the passion of the attraction of existing tourism potential needs to be improved and new potential that can inc
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FRANCH, Jesper, Rune ASLESEN, and Jørgen JENSEN. "Regulation of glycogen synthesis in rat skeletal muscle after glycogen-depleting contractile activity: effects of adrenaline on glycogen synthesis and activation of glycogen synthase and glycogen phosphorylase." Biochemical Journal 344, no. 1 (1999): 231–35. http://dx.doi.org/10.1042/bj3440231.

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We investigated the effects of insulin and adrenaline on the rate of glycogen synthesis in skeletal muscles after electrical stimulation in vitro. The contractile activity decreased the glycogen concentration by 62%. After contractile activity, the glycogen stores were fully replenished at a constant and high rate for 3 h when 10 m-i.u./ml insulin was present. In the absence of insulin, only 65% of the initial glycogen stores was replenished. Adrenaline decreased insulin-stimulated glycogen synthesis. Surprisingly, adrenaline did not inhibit glycogen synthesis stimulated by glycogen-depleting
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46

Sirota, T. V. "Standardization and regulation of the rate of the superoxide-generating adrenaline autoxidation reaction used for evaluation of pro/antioxidant properties of various materials." Biomeditsinskaya Khimiya 62, no. 6 (2016): 650–55. http://dx.doi.org/10.18097/pbmc20166206650.

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The superoxide-generating reaction of adrenaline autoxidation is widely used for determination of the activity of superoxide dismutase and pro/antioxidant properties of various materials. There are two variants of the spectrophotometric registration of the products of this reaction. The first is based on registration of adrenochrome, as adrenaline autooxidation product at 347 nm; the second employs nitro blue tetrazolium (NBT) and registration of diformazan, a product of NBT reduction at 560 nm. In the present work, recommendations for the standardization of the reaction rate in both variants
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47

Tsuchiya, Yugo, Fiona C. Denison, Richard B. Heath, David Carling, and David Saggerson. "5′-AMP-activated protein kinase is inactivated by adrenergic signalling in adult cardiac myocytes." Bioscience Reports 32, no. 2 (2011): 197–209. http://dx.doi.org/10.1042/bsr20110076.

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In adult rat cardiac myocytes adrenaline decreased AMPK (AMP-activated protein kinase) activity with a half-time of approximately 4 min, decreased phosphorylation of AMPK (α-Thr172) and decreased phosphorylation of ACC (acetyl-CoA carboxylase). Inactivation of AMPK by adrenaline was through both α1- and β-ARs (adrenergic receptors), but did not involve cAMP or calcium signalling, was not blocked by the PKC (protein kinase C) inhibitor BIM I (bisindoylmaleimide I), by the ERK (extracellular-signal-regulated kinase) cascade inhibitor U0126 or by PTX (pertussis toxin). Adrenaline caused no measur
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48

Al-Damluji, S., D. Cunnah, A. Grossman, et al. "Effect of adrenaline on basal and ovine corticotrophin-releasing factor-stimulated ACTH secretion in man." Journal of Endocrinology 112, no. 1 (1987): 145–50. http://dx.doi.org/10.1677/joe.0.1120145.

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ABSTRACT Six normal male subjects were given, in single blind random order on six separate occasions, i.v. bolus doses of synthetic ovine corticotrophin-releasing factor-41 (oCRF-41; 25 and 50 μg) with and without adrenaline (3 μg/min) i.v. for 150 min, the adrenaline infusions alone and saline placebo. The adrenaline infusions resulted in plasma adrenaline concentrations of 4·33 ± 0·82 (s.e.m.) nmol/l and were associated with an increase in blood glucose, heart rate and systolic blood pressure and a reduction of diastolic blood pressure. Despite these evident biological effects at several sit
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49

Fellows, I. W., I. A. MacDonald, T. Bennett, and D. P. O'Donoghue. "Effect of intravenous infusion of adrenaline on the cardiovascular responses to distal body subatmospheric pressure in man." Clinical Science 75, no. 4 (1988): 389–94. http://dx.doi.org/10.1042/cs0750389.

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1. On two separate occasions, at least 1 week apart, seven young healthy male subjects received intravenous infusions of either adrenaline [0.27 nmol (50 ng) min−1 kg−1] or saline (154 mmol/l NaCl), plus ascorbic acid (5.68 mmol/l), over 30 min. 2. On each occasion, the subjects were exposed to distal body subatmospheric pressure (DBSP), 0 to 50 mmHg (0 to 6.65 kPa) in 10 mmHg (1.33 kPa) steps, before infusion, during the final 15 min of the infusion, and at 15 min and 30 min after the cessation of the infusion. 3. Venous adrenaline concentrations of 2.85 ±0.22 nmol/l were achieved during the
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50

BRAITHWAITE, B. D., G. J. ROBINSON, and P. D. BURGE. "Haemostasis During Carpal Tunnel Release Under Local Anaesthesia: A Controlled Comparison of a Tourniquet and Adrenaline Infiltration." Journal of Hand Surgery 18, no. 2 (1993): 184–86. http://dx.doi.org/10.1016/0266-7681(93)90103-m.

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A randomized controlled comparison of tourniquet and local adrenaline infiltration for control of bleeding was performed in patients undergoing bilateral carpal tunnel release under local anaesthesia. Visual analogue scores for intra-operative pain were substantially greater for tourniquet (mean score 4.7) than for adrenaline (2.2). Incomplete control of bleeding was responsible for longer operating time and for the surgeons’ perception of slightly greater operative difficulty with the use of adrenaline. There were no complications attributable to the use of adrenaline. The use of adrenaline-c
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