Academic literature on the topic 'Adult Diagnostic and Treatment Center'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Adult Diagnostic and Treatment Center.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Adult Diagnostic and Treatment Center"
1
Zgoba, Kristen M., Wayne R. Sager, and Philip H. Witt. "Evaluation of New Jersey's Sex Offender Treatment Program at the Adult Diagnostic and Treatment Center: Preliminary Results." Journal of Psychiatry & Law 31, no. 2 (2003): 133–64. http://dx.doi.org/10.1177/009318530303100202.
Full textAbstract:
This study examined 10-year sexual and non-sexual offense recidivism for sex offenders released from New Jersey's general prison system and from the Adult Diagnostic and Treatment Center (ADTC), New Jersey's correctional facility and treatment center for repetitive-compulsive sexual offenders. The study found that sexual offenders released from the ADTC had significantly lower rates of committing both non-sexual offenses and any offense, compared with the general prison population of sex offenders. For both groups, the 10-year sexual offense reconviction rates were relatively low, 8.6% for the ADTC offenders and 12.7% for the general prison sexual offenders, while reoffense rates for non-sexual offenses were 25.8% and 44.1% for ADTC and general prison sex offenders, respectively.
2
Egeli, B., and S. Ugurlu. "POS1369 ADULT-ONSET STILL’S DISEASE: A SINGLE-CENTER EXPERIENCE." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 966.2–966. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3280.
Full textAbstract:
Background:Adult-Onset Still’s disease (AOSD) is an autoinflammatory condition characterized by fever, rash, and arthritis. The diagnosis of AOSD is made by excluding common causes of fever of unknown origin which are infections, malignancies, autoimmune conditions and medication adverse effects. As it is a diagnostic challenge, further data on highlighting clinical and laboratory findings are necessary on guiding clinicians.Objectives:Our main objective is to present our single tertiary center experience of patients diagnosed with AOSD.Methods:This retrospective study was conducted at a tertiary rheumatology center. Patients were diagnosed with AOSD using Yamaguchi’s criteria and followed between 2007 and 2020. Demographic, clinical and laboratory information was retrieved from the patient chars. Treatment-related and prognostic information were also noted with additional information from phone call interviews.Results:The study includes 69 patients (23 M, 46 F). The mean age of diagnosis was 33.86±14.3. The presenting signs and symptoms of the patients are shown in Figure 1. The laboratory findings supporting the diagnosis at initial encounter are summarized in Table 1. The mean corticosteroid dose at initial diagnosis was 29.7±18 mg. In addition to corticosteroid treatment these patients were followed with different glucocorticoid-sparing agents. Methotrexate was the choice of treatment in 54 patients with the mean dose of 14.5±3.43 mg. Eight patients were treated with leflunomide, seven with anti-TNF agents, seven with tocilizumab, nineteen with anakinra and four with canakinumab.Figure 1.The presenting signs and symptoms of the patientsConclusion:In conclusion, the most common presenting symptoms in our AOSD cohort were fever and salmon-colored rash. In the differential diagnosis of fever of unknown origin especially with rash, AOSD should be considered. Corticosteroid was the main treatment modality. In patients who are unresponsive to conventional immunosuppressive treatment, biologic agents can be an alternative.Table 1.The laboratory findings at initial encounterMean ± Standard DeviationFerritin (ng/mL)3179.46±6503.56ESR (mm/h)77.43±28.47CRP (mg/L)102.29±70.39Leukocyte Count (cells/L)13147.3±4640.9ESR (mm/h)80±28.48CRP (mg/L)105.15±54.67Leukocyte Count (cells/L)12427.14±6530.43Disclosure of Interests:None declared
3
Dzhordzhikiya, R. K., I. I. Vagizov, G. I. Kharitonov, I. V. Bilalov, and M. N. Mukharyamov. "Changes in tactics and treatment results in congenital heart diseases in adults during the last 15 years (investigation based on the data of cardio-surgical departments of the Republic of Tatarstan)." Kazan medical journal 96, no. 4 (2015): 623–28. http://dx.doi.org/10.17750/kmj2015-623.
Full textAbstract:
Aim. To summarize and to distinguish the features of diagnosis and treatment of congenital heart diseases in adults characteristic for the contemporary cardio surgery, by a retrospective study of case reports.
 Methods. The study analyzed the medical charts of 245 adults with congenital heart diseases treated in the Cardio surgical department №2 of the Interregional Clinical and Diagnostic Center between 2007 and 2015 years. The comparison group included 701 adult patients with congenital heart diseases treated in the Kazan Center of Cardiovascular surgery between 1987 and 1997.
 Results. The prevalence of congenital heart diseases in adults remains significant. In recent years, the share of operations for these diseases is 5.4% of all cardiac interventions. The most frequent pathology is atrial septal defects. The most frequent complications of septal defects are tricuspidal valve insufficiency (83%) and pulmonary hypertension (77%). Comorbidities include: hypertensive heart disease (36%), cardiac arrhythmias (31%) and ischemic heart disease (33%). The number surrendered surgeries decreased from 28.8% in 1997 to 3.7% in 2014. Postoperative mortality has decreased from 3.3% to 1%. Nowadays a significant amount of operations (56%) is transcatheter occlusion. There is an experience of such surgeries in defects of secondary atrial septum and patent ductus arteriosus.
 Conclusion. Congenital heart diseases in adults are characterized by severe impairment of haemodynamics, leading to arterial pulmonary hypertension and tricuspid insufficiency, therefore, require early diagnostics and timely treatment before the onset of complications. 68% of such adult patients suffer from comorbidities that increase the risk of surgical interventions. Endovascular surgeries are low invasive, have minimal complication rate and produce good immediate and long-term results.
4
Petryaykina, E. E., I. O. Shchederkina, I. P. Vitkovskaya, et al. "Primary pediatric stroke center in the multidisciplinary pediatric hospital. New reality in pediatrics." City Healthcare 1, no. 1 (2020): 15–30. http://dx.doi.org/10.47619/2713-2617.zm.2020.v1i1;15-30.
Full textAbstract:
Background. The increase in the number of diagnosed strokes in children, significant distinctive features and complexity of diagnosis, treatment and prevention of cerebrovascular diseases in children compared with adults, the impossibility of direct extrapolation of therapeutic recommendations from adult practice to pediatrics required the creation of specialized primary centers of pediatric stroke in Russia. Purpose. The purpose of this article is to describe the experience of organizing a Center for the treatment of children and adolescents with cerebrovascular diseases (hereinafter referred to as the Center) on the basis of the multidisciplinary pediatric hospital of the Morozovskaya Children's City Clinical Hospital of Moscow Healthcare Department, the introduction of modern methods of diagnosis and treatment of strokes in pediatrics, the organization of preventive measures, maintaining the city register of children's stroke, coordinating the provision of medical care to children with cerebrovascular diseases at various levels in the city of Moscow. Materials and methods. The presented experience of organizing and operating the Center covers the period from 2014 to 2019. Researchers used descriptive, statistical, and comparative analysis to demonstrate the Center's performance and justify proposed improvements in diagnostics, management of pediatric patients with cerebrovascular disease, and relapse prevention. Results. In the course of the organization and operation of the Center, there was assessed the frequency of children's strokes in the city: in 2015 - 6.59 cases per 100 thousand of the child population of Moscow; in 2016 - 6.51 per 100 thousand; in 2017 - 6.43 per 100 thousand and in 2018 - 5.86 per 100 thousand. There were improved: the diagnostics of cerebrovascular pathology and its algorithm, modern reperfusion methods of treatment (thrombolysis, thromboextraction) were introduced into practice, outpatient observation. The equipment and trained specialists concentration on the basis of the Center allowed the creation of the Center "full cycle". Maintaining the city register of pediatric stroke made it possible to compare Russian data with those available in the literature and to establish international cooperation with the International Pediatric Stroke Organization. Conclusion. The establishment of the Center is an important example of interdisciplinary interaction in pediatrics. The City Register of Pediatric Stroke will make it possible to assess the problem of childhood stroke in Moscow. The accumulated organizational, medical and diagnostic, scientific, international and educational experience of the Center can be introduced in other regions of the Russian Federation to improve the provision of medical care to children and to solve the most important problem - preserving the health of the country's child population.
5
Vlasova, A. V., T. A. Tenovskaya, L. V. Dymnova, et al. "Primary pediatric stroke center in the multidisciplinary pediatric hospital. New reality in pediatrics." City Healthcare 1, no. 1 (2020): 51–59. http://dx.doi.org/10.47619/2713-2617.zm.2020.v1i1;51-59.
Full textAbstract:
Background. The increase in the number of diagnosed strokes in children, significant distinctive features and complexity of diagnosis, treatment and prevention of cerebrovascular diseases in children compared with adults, the impossibility of direct extrapolation of therapeutic recommendations from adult practice to pediatrics required the creation of specialized primary centers of pediatric stroke in Russia. Purpose. The purpose of this article is to describe the experience of organizing a Center for the treatment of children and adolescents with cerebrovascular diseases (hereinafter referred to as the Center) on the basis of the multidisciplinary pediatric hospital of the Morozovskaya Children’s City Clinical Hospital of Moscow Healthcare Department, the introduction of modern methods of diagnosis and treatment of strokes in pediatrics, the organization of preventive measures, maintaining the city register of children’s stroke, coordinating the provision of medical care to children with cerebrovascular diseases at various levels in the city of Moscow. Materials and methods. The presented experience of organizing and operating the Center covers the period from 2014 to 2019. Researchers used descriptive, statistical, and comparative analysis to demonstrate the Center’s performance and justify proposed improvements in diagnostics, management of pediatric patients with cerebrovascular disease, and relapse prevention. Results. In the course of the organization and operation of the Center, there was assessed the frequency of children’s strokes in the city: in 2015 - 6.59 cases per 100 thousand of the child population of Moscow; in 2016 - 6.51 per 100 thousand; in 2017 - 6.43 per 100 thousand and in 2018 - 5.86 per 100 thousand. There were improved: the diagnostics of cerebrovascular pathology and its algorithm, modern reperfusion methods of treatment (thrombolysis, thromboextraction) were introduced into practice, outpatient observation. The equipment and trained specialists concentration on the basis of the Center allowed the creation of the Center «full cycle». Maintaining the city register of pediatric stroke made it possible to compare Russian data with those available in the literature and to establish international cooperation with the International Pediatric Stroke Organization. Conclusion. The establishment of the Center is an important example of interdisciplinary interaction in pediatrics. The City Register of Pediatric Stroke will make it possible to assess the problem of childhood stroke in Moscow. The accumulated organizational, medical and diagnostic, scientific, international and educational experience of the Center can be introduced in other regions of the Russian Federation to improve the provision of medical care to children and to solve the most important problem - preserving the health of the country’s child population.
6
Thomas, John, Prasanth Thangavel, Wei Yan Peh, et al. "Automated Adult Epilepsy Diagnostic Tool Based on Interictal Scalp Electroencephalogram Characteristics: A Six-Center Study." International Journal of Neural Systems 31, no. 05 (2021): 2050074. http://dx.doi.org/10.1142/s0129065720500744.
Full textAbstract:
The diagnosis of epilepsy often relies on a reading of routine scalp electroencephalograms (EEGs). Since seizures are highly unlikely to be detected in a routine scalp EEG, the primary diagnosis depends heavily on the visual evaluation of Interictal Epileptiform Discharges (IEDs). This process is tedious, expert-centered, and delays the treatment plan. Consequently, the development of an automated, fast, and reliable epileptic EEG diagnostic system is essential. In this study, we propose a system to classify EEG as epileptic or normal based on multiple modalities extracted from the interictal EEG. The ensemble system consists of three components: a Convolutional Neural Network (CNN)-based IED detector, a Template Matching (TM)-based IED detector, and a spectral feature-based classifier. We evaluate the system on datasets from six centers from the USA, Singapore, and India. The system yields a mean Leave-One-Institution-Out (LOIO) cross-validation (CV) area under curve (AUC) of 0.826 (balanced accuracy (BAC) of 76.1%) and Leave-One-Subject-Out (LOSO) CV AUC of 0.812 (BAC of 74.8%). The LOIO results are found to be similar to the interrater agreement (IRA) reported in the literature for epileptic EEG classification. Moreover, as the proposed system can process routine EEGs in a few seconds, it may aid the clinicians in diagnosing epilepsy efficiently.
7
Rosenberg, Anna G. W., Minke R. A. Pater, Kirsten Davidse, et al. "What Every Internist Should Know About Rare Genetic Syndromes in Order to Prevent Needless Diagnostics, Missed Diagnoses and Medical Complications: Five-Year Experience of Internal Medicine for Complex Rare Genetic Syndromes." Journal of the Endocrine Society 5, Supplement_1 (2021): A513—A514. http://dx.doi.org/10.1210/jendso/bvab048.1050.
Full textAbstract:
Abstract Introduction: Patients with complex rare genetic syndromes (CRGS) have, by definition, combined medical problems affecting multiple organ systems. Intellectual disability (ID) is often part of the syndrome. During childhood, most patients with CRGS receive multidisciplinary (MD) and specialized pediatric care in tertiary centers. As improvement of medical care has improved life expectancy, more and more patients are now reaching adult age. While the complexity of the syndromes persist into adulthood, adequate multidisciplinary syndrome-specific care is rarely available for adults with CRGS. Although multiple organ systems are usually affected, internists are rarely involved. Pediatricians have expressed the urgent need for adequate, syndrome-specific, MD tertiary healthcare for adults with CRGS. Methods: In 2015 we have launched the Center for Adults with CRGS, a specialized MD outpatient clinic (MOPC) within the Endocrinology unit of the department of Internal Medicine. As adult manifestations are unknown for most CRGS, all CRGS patients who visit our MOPC undergo a systematic health screening (followed by treatment, if indicated). Before visiting the MOPC, caregivers fill out a medical questionnaire. We gathered the physical complaints, medication use and missed diagnoses of 726 adults with CRGS. Results: Between 2015 and 2020, 256 males and 470 females with over 60 syndromes visited the Center for Adults with CRGS. The main features of this population, as compared with general internal medicine patients, were intellectual disability, polypharmacy and use of psychotropic drugs. Missed diagnoses were common and many patients had undergone extensive diagnostic tests for symptoms that could actually be explained by their syndrome. Fatigue (52%), abdominal discomfort (23%) and hypertension (10%) were among the most frequent reasons for referral to Internal Medicine. Based on the literature and our clinical findings, 73% of the syndromes was associated with endocrine problems. We provide an algorithm for the clinical approach to CRGS adults, in order to prevent unnecessary diagnostics as well as missed diagnoses. Conclusion: Our overview of 726 adults with CRGS shows that missed diagnosed and needless invasive tests are common in this patient population. As more and more CRGS patients are now reaching adult age and transfer to Internal Medicine, internists and endocrinologists should be aware of the special needs of adults with CRGS and of the medical pitfalls. Knowledge about syndrome-specific health problems and multidisciplinary expert care is crucial to prevent the personal and financial burden of unnecessary diagnostics and under- and overtreatment.
8
Esaulenko, Elena Vladimirovna, and Anastasiya Aleksandrovna Sukhoruk. "Liver transplantation in children and adults." Pediatrician (St. Petersburg) 6, no. 3 (2015): 98–103. http://dx.doi.org/10.17816/ped6398-103.
Full textAbstract:
The article presents an analysis of modern domestic and foreign literature on the problems of liver transplantation in children and adults. Liver transplantation is performed for more than 50 years and it has become a reliable, rational way, and sometimes the only life-saving treatment for children and adults suffering from diffuse liver disease or unresectable tumors. Currently, the Russian Federation opened 14 centers for liver transplantation (in Moscow, St. Petersburg, Belgorod, Krasnodar, Irkutsk, Novosibirsk, Yekaterinburg and Nizhniy Novgorod), which is performed annually 200-240 operations. Estimated demand for the provision of this service is much higher: 52-64 center, and 2000-2500 operations per year. However, liver transplantation in children performs only in two centers in Moscow. Possibility of timely planning of liver transplantation in children of any age has now become a reality, but with a very limited capacity. Recently there has been improvement in diagnostic capabilities to identify various congenital and acquired diseases of the liver in children requiring liver transplantation. We can already predict the increase in demand for this type of surgery. In the North-Western Federal District is a center in which possible liver transplantation in adults, while the children’s opportunities for transplantation in the region do not have. The reasons leading to liver transplantation in children and adults are different. In adult practice dominated by cirrhosis in the outcome of chronic viral hepatitis B and C, whereas in children biliary atresia and congenital metabolic disorders.
9
Gallucci, Fernando, Ilaria Ronga, Francesco Di Pietto, Gerardino Amato, Rosario Buono, and Generoso Uomo. "Adult bacterial myositis: report of a single-center series of 26 cases." Italian Journal of Medicine 10, no. 3 (2016): 226. http://dx.doi.org/10.4081/itjm.2016.667.
Full textAbstract:
Bacterial infections involving muscle are quite uncommon and generally require specific predisposing factors. Bacterial myositis is more rarely described in the typical kind of patients observed in Internal Medicine (presence of multiple co-morbidities, partial/limited immune-deficiency, advanced age). Twenty-six patients suffering from bacterial myositis (8 women and 18 men; mean age 58.5 years, range 27-82) observed in a single Internal Medicine Unit were reported. Muscles involved were ileopsoas, thigh, paravertebral, gluteus, calf, forearm and rectus abdomen. Simultaneous presence of arthritis was registered in 17 patients and all patients presented relevant comorbidity. Main cultured bacteria were <em>Staphylococcus aureus, Escherichia coli</em>, other Gram-negative bacteria, <em>Streptococcus spp.</em> Multi-drug-resistance was observed in 14 out 26 (53.8%). Computed tomography, ultrasound and magnetic resonance imaging were utilized for diagnostic purposes. Antibiotic treatment was administered to all patients. Surgical debridement and drainage were performed in 12 patients; 7 patients were treated with percutaneous aspiration and drainage. At discharge, relevant functional impairment was present in 17 patients (65.3%). Four patients died (in-hospital mortality 7.6%, global mortality at three months 15.3%). Management of bacterial myositis is difficult and its prognosis is poor. In the near future, this demanding infection will be more frequently observed in Internal Medicine setting as comorbidity, which is very often the main characteristic of these patients.
10
Janssen, Nico A. F., Roger J. M. Brüggemann, Monique H. Reijers, et al. "A Multidisciplinary Approach to Fungal Infections: One-Year Experiences of a Center of Expertise in Mycology." Journal of Fungi 6, no. 4 (2020): 274. http://dx.doi.org/10.3390/jof6040274.
Full textAbstract:
Invasive fungal diseases (IFDs) often represent complicated infections in complex patient populations. The Center of Expertise in Mycology Radboudumc/CWZ (EMRC) organizes a biweekly multidisciplinary mycology meeting to discuss patients with severe fungal infections and to provide comprehensive advice regarding diagnosis and treatment. Here, we describe the patient population discussed at these meetings during a one-year period with regards to their past medical history, diagnosis, microbiological and other diagnostic test results and antifungal therapy. The majority of patients discussed were adults (83.1%), 62.5% of whom suffered from pulmonary infections or signs/symptoms, 10.9% from otorhinolaryngeal infections and/or oesophagitis, 9.4% from systemic infections and 9.4% from central nervous system infections. Among children, 53.8% had pulmonary infections or signs/symptoms, 23.1% systemic fungal infections and 23.1% other, miscellaneous fungal infections. 52.5% of adult patients with pulmonary infections/symptoms fulfilled diagnostic criteria for chronic pulmonary aspergillosis (CPA). Culture or polymerase chain reaction (PCR) demonstrated fungal pathogens in 81.8% of patients, most commonly Aspergillus. A multidisciplinary mycology meeting can be a useful addition to the care for patients with (I)FDs and can potentially aid in identifying healthcare and research needs regarding the field of fungal infections. The majority of patients discussed at the multidisciplinary meetings suffered from pulmonary infections, predominantly CPA.
Dissertations / Theses on the topic "Adult Diagnostic and Treatment Center"
1
van, Zyl Karina Marie. "Adults living with stimulant abuse and bipolar disorder: Experiences of service users at treatment centres." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/62665.
Full textAbstract:
The goal of the study was to explore how adults living with stimulant abuse and bipolar disorder experience treatment at treatment centres in the Gauteng Province. As the study was aimed at gaining an in-depth understanding of the lived experiences of service users in terms of treatment, a qualitative research approach was implemented. The research findings were aimed at adding knowledge to the field of social work, which could contribute to the development of treatment programmes and possible policy changes that could positively impact the recovery of individuals living with a dual-diagnosis, specifically the dual-diagnosis of bipolar disorder and stimulant abuse. A phenomenological research design was used as it allowed the researcher to discover and report on the details pertaining to the participants' experiences in terms of the treatment they received. The phenomenological research design also enabled the researcher to describe the commonalities and discords expressed by participants in relation to the phenomenon. The sampling process for the research study took place in three phases. In the first phase, purposive sampling was implemented to select three substance abuse treatment centres in the Gauteng Province, and more specifically the Tshwane Metropolitan Municipality. The second phase of sampling was also purposive sampling, where inclusion criteria were supplied to a social worker at each treatment centre who identified possible participants. During the third phase of sampling, possible participants were approached and informed of the study and ultimately four (N=4) individuals volunteered to participate in the study. Data was collected through the use of semi-structured one-on-one interviews which were guided by an interview schedule. Data gathered during the literature review and interviews were analysed through the process of thematic analysis and aimed at answering the research question "How do adults living with stimulant abuse and bipolar disorder experience services at treatment centres in the Gauteng Province?" The key findings indicate that admission to in-patient treatment programmes, for both stimulant abuse and psychiatric care, was prevalent among all participants, but re-occurring admissions to substance abuse treatment was more evident. Stimulants were primarily used as a means of coping with moods and emotions, as unstable mood patterns and emotions persisted regardless of the pharmacological treatment for bipolar disorder. The most helpful component of treatment which aided participants in managing their mood was counselling. When stimulants were not available and counselling was insufficient, other means of achieving psychological relieve were employed by participants, such as exercise, nicotine use, sweets and caffeine. The role of religion and spirituality in treatment is not clear, but all participants believe that religion and spirituality should be included in treatment. The need for education in terms of bipolar disorder, addictive behaviours, lifestyle changes and coping mechanisms were mentioned by most participants. In addition to education provided by professionals, participants expressed a need for sharing experiences with individuals that have managed to recover from bipolar disorder and/or stimulant abuse. When treatment plans and goals are set participants believe that they and their family should be included, a factor relevant to in-patient and reintegration services. With regards to in-patient treatment programmes, the psychosocial-cultural environment created within the physical environment was also mentioned as a component that needs to be considered. In order to deliver services that allow for the effective treatment and reintegration of individuals that abuse stimulants and are diagnosed with bipolar disorder the following recommendations are made: 1) Interventions, including prevention and early interventions, should be developed based on research findings focused on dual-diagnosis, to ensure that concurrent treatment and reintegration is achieved and sustained, thus promoting recovery, or the management, of both disorders. 2) Education in terms of stimulant addiction, cross-addiction, bipolar disorder, lifestyle changes, coping skills, as well as the interplay between these factors should be included in treatment programmes, however, education should be expanded to service providers and extended to family members too. 3) The role of religion and spirituality as part of dual-diagnosis treatment should be considered. 4) Treatment and support groups that focus on the specific dual-diagnosis of stimulant use and bipolar disorder, should be developed as part of in-patient treatment programmes, as well as supporting out-patient programmes, which could improve long-term recovery. 5) The physical and the psychosocial environments which are conducive to the recovery of dual-diagnosis patients should be established, as these environments could possibly be replicated, for example at home, and could ensure long-term recovery. 6) Service users and their families should be included in decisions regarding treatment planning and reintegration, as inclusion in this area of treatment could promote compliance to treatment. However, it should be stated that many of these recommendations are dependent on governing bodies, such as the Department of Social Development and the Department of Health, who are responsible for changing, developing and monitoring policies guiding treatment, which has a direct impact on the long-term recovery of individuals living with this dual-diagnosis. Future research studies that can contribute to understanding this phenomenon can focus on 1) Repeating the study within other private and government based treatment centres across South Africa in order to determine whether treatment needs differ or whether it presents the same results. 2) Comparing studies from different centres and areas of South Africa in order to establish treatment needs of individuals diagnosed with a dual-diagnosis. 3) Research should be done to determine the actual prevalence of the dual-diagnosis of stimulant abuse and bipolar disorder in South Africa, focused on admissions in both substance abuse treatment centres and psychiatric treatment facilities. 4) Treatment programmes developed from research findings should be implemented, and research should be conducted on the effectiveness of treatment. 5) Research on different combinations of dual-diagnosis is necessary to determine how treatment needs differ, as this will ensure the development of appropriate treatment. Individuals working at treatment centres (for both substance abuse and psychiatric disorders) should be aware of the needs of dual-diagnosis patients, and be educated on this phenomenon. 6) It is recommended that research should be done with the staff of psychiatric treatment centres, as well as staff at substance abuse treatment centres, to determine their views and knowledge in terms of dual-diagnosis. 7) Research focussed on the costs of not treating dual-diagnosis should be conducted. When the actual costs of non-treatment are established, government agencies and the private sector might be more prone to support treatment strategies. 8) Intervention strategies focused on families of dual-diagnosis patients should be implemented and the impact of these interventions on both patients and families should be researched. 9) More research in terms of this dual-diagnosis is necessary as this could allow for the development of effective treatment strategies that could lower relapse and readmission rates.<br>Mini Dissertation (MSW)--University of Pretoria, 2017.<br>Social Work and Criminology<br>MSW<br>Unrestricted
2
Hunter, Robert A. (Robert Allan). "Evaluation of the Preparation for Adult Living Training Program for Severely Emotionally Disturbed Adolescents in a Residential Treatment Center." Thesis, University of North Texas, 1993. https://digital.library.unt.edu/ark:/67531/metadc278755/.
Full textAbstract:
The purpose of this study was to determine the effectiveness of the Preparation for Adult Living skills training program by measuring the learning gains and learning outcomes of students participating in the training. The quasi-experimental posttest control group design was used. A treatment sample of twelve students received the Preparation for Adult Living training. A nontreatment sample was selected by matching the characteristics of educational and reading level and the gender of twelve students with no previous independent living skills training with those of the treatment sample. Students in the treatment sample were tested for learning gains using the Preparation for Adult Living Test. Both the treatment and nontreatment sample were tested using the post-training Preparation for Adult Living Scale to determine the level of their learning outcomes. The Preparation for Adult Living Test results were analyzed using the t-test for correlated samples of pretests and posttests. The t-test for independent samples was used to analyze the Preparation for Adult Living Scale results to determine the students' learning outcomes. A Pearson r correlation coefficient was calculated for Preparation for Adult Living Scale scores to determine if a relationship existed between employment and the life coping skills of the treatment sample. The findings indicated that no learning gains were made during the training, but that the training had an impact on the students' post-training life-coping skills. A strong relationship was found between the specific life-coping and employment skills of the treatment sample. Investigation of the reliability and validity of the Preparation for Adult Living Test and Scale instruments was recommended.
3
LASURE-BRYANT, DANIELLE RENEE. "CORRELATES OF GLOBAL ASSESSMENT OF FUNCTIONING (GAF) SCORES FOR OLDER ADULT USERS OF A COMMUNITY MENTAL HEALTH CENTER." University of Cincinnati / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1030105772.
Full text
4
Lee, Jung-Ah. "A review of the management of patients at risk for or diagnosed with venous thromboembolism (VTE) at an academic medical center, and the cost-effectiveness of diagnostic strategies for VTE /." Thesis, Connect to this title online; UW restricted, 2008. http://hdl.handle.net/1773/7224.
Full text
5
MIAO-PING, CHEN, and 陳妙平. "Exploration of the relapse determinants of male adult drug addicts ~ The study conducted in Taipei Drug Abuser Treatment Center." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/51936036853415246455.
Full textAbstract:
碩士<br>輔仁大學<br>社會工作學系<br>93<br>Exploration of the relapse determinants of male adult drug addicts
~ The study conducted in Taipei Drug Abuser Treatment Center
Abstract
The purpose of this research is to explore the factors that cause the relapse of drug addicts. The participants of this study are ten court-ordered adults who are immured at Taipei Drug Abuser Treatment Center. This study is a qualitative research that generalizes a conclusion from interviewing ten drug abusers.
The results of this research reveal that the determinants of relapse can be categorized into two kinds. One is retrospective, and another is prospective. The retrospective relapse determinants also can be differentiated into the previous determinants and the catalytic determinants. Then, the retrospective and prospective relapse determinants are separated into two categories: intra-personal determinants and external-environmental determinants. Next are the detail contents.
一、Retrospective Relapse Determinants
（一）The Previous Relapse Determinants
1. Intra-personal determinants
(1) Craving for drug and lack of coping skills.
(2) The irrational or erroneous belief of the drug.
(3) No motivation or weak commitment to abstinence.
(4) Meaninglessness of life.
2. External-environmental determinants
(1) The effect of life frustration.
(2) The influence of interpersonal relationship.
(3) Problems with the law.
(4) Reduction of external monitor.
(5) Codependence in the family.
（二）The Catalytic Relapse Determinants
1. Intra-personal determinants
(1) Continuing craving for drug and lack of coping skills.
(2) The irrational or erroneous belief of the drug.
(3) No motivation or weak commitment to abstinence.
(4) Rationalizations for using the drug.
(5) Low self-efficacy to abstinence.
(6) The effect of alcohol.
(7) Seeking release from internal conflict.
2. External-environmental determinants
(1) The negative emotion that result from the life frustration.
(2) Social pressure and demand.
(3) Availability of drug.
(4) Testing the drug for the various reasons.
(5) Financial capability.
二、Prospective Relapse Determinants
（一） Intra-personal determinants
1. Have no confidence and skills to abstinence from drugs.
2. To suffer from drug craving.
3. Meaninglessness of life.
（二）External-environmental determinants
1. The influence of interpersonal relationship.
2. The family factors.
3. Unexpected life frustration.
4. Have drug-related event.
5. Financial capability.
6. Surrounded by the drugs for life.
7. Problems with the law.
Finally, we hope that the result of this research will provide the consultation to the practice workers who treat the addicts. That will contribute to develop the therapeutic programs and prevent relapse, thus, it will reduce the social problems and the cost.
6
Lin, Chiung-Tsung, and 林炯璁. "A Study of The Emergency Department of a Tertiary Care Medical Center in Central Taiwan Adult Patients Diagnostic Values of Procalcitonin, Lactate and High-sensitivity C-reactive Protein with Blood Cultures." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/x2526v.
Full textAbstract:
博士<br>亞洲大學<br>生物資訊與醫學工程學系<br>106<br>Sepsis has a high mortality rate that can be effectively decreased with early treatment, but the initial diagnosis is difficult. Blood culture is the diagnostic standard for bacterial sepsis, however, blood culture, including identification and antibiotic sensitivity test, requires at least 12- 48 h; hence the development of early-stage diagnosis is critical. C-reactive protein (CRP) or white blood cell (WBC) values are commonly used as a basis for diagnosis, but since they have low specificity, other new markers are needed. In the past decade, procalcitonin (PCT) has been used as an early diagnostic tool. This study focuses on the prediction differences between PCT, lactate, and high-sensitivity C-reactive protein (hs-CRP) and bacterial blood culture of adults with bacterial sepsis in the emergency department. The detection capabilities for gram-positive and gram-negative bacteria are discussed separately. The results of this study show that procalcitonin has an acceptable discriminative ability for bacterial blood culture and a better discriminative ability for gram-negative bacteremia（AUR=0.786 area under the ROC curve）when compared with lactate and high-sensitivity C-reactive protein. It can also for distinguishing blood bacterial culture results of contamination and positivity. High-sensitivity C-reactive protein at a cutoff of 0.8 mg/dL provides poor prediction of positive bacterial culture and it is unable to distinguish for all positive pathogen from contaminants.
Books on the topic "Adult Diagnostic and Treatment Center"
1
New Jersey. Legislature. Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center. Meeting of the Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center: Testimony regarding the therapy program of the Adult Diagnostic and Treatment Center. The Task Force, 1995.
Find full text
2
New Jersey. Legislature. Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center. Report of the Joint Task Force to Study the Adult Diagnostic and Treatment Center. New Jersey State Legislature, Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center, 1995.
Find full text
3
New Jersey. Legislature. Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center. Meeting of the Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center: Testimony regarding therapy and programs. The Task Force, 1994.
Find full text
4
New Jersey. Legislature. Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center. Meeting of the Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center: Testimony from superintendent and treatment staff : [November 1, 1994, Avenel, New Jersey]. Office of Legislative Services, Public Information Office, Hearing Unit, 1994.
Find full text
5
New Jersey. Legislature. Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center. Meeting of the Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center: Testimony regarding the reorganization of the ADTC therapy program : [February 1, 1995, Woodbridge, New Jersey]. Office of Legislative Services, Public Information Office, Hearing Unit, 1995.
Find full text
7
University of the State of New York. Office of Audit Services. Audit report, Sullivan County, audit of the Sullivan Diagnostic Treatment Center preschool program. University of the State of New York, State Education Dept., Office of Audit Services, 2000.
Find full text
8
Brenda, Freishtat, Zoltan Barbara, and Siev Ellen, eds. Perceptual and cognitive dysfunction in the adult stroke patient: A manual for evaluation and treatment. SLACK, 1986.
Find full text
9
Selecting effective treatments: A comprehensive, systematic guide to treating adult mental disorders. Jossey-Bass Publishers, 1990.
Find full text
10
J.J. Sandra Sandra Kooij. Adult ADHD: Diagnostic Assessment and Treatment. Springer, 2015.
Find full textBook chapters on the topic "Adult Diagnostic and Treatment Center"
1
Markham, David E. "Diagnostic strategy for adult soft tissue sarcomas." In Cancer Treatment and Research. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2319-8_2.
Full text
2
Fontana, Giovanni A., Guja Bernacchi, and Alessio Fabbrizzi. "Diagnostic Approach in Adult Patients with Chronic Cough." In Cough: Pathophysiology, Diagnosis and Treatment. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-48571-9_10.
Full text
3
"ADULT DIAGNOSTIC ASSESSMENT." In Treatment Planning for Person-Centered Care. Elsevier, 2005. http://dx.doi.org/10.1016/b978-012044155-6/50019-2.
Full text
4
Boterberg, Tom, Karin Dieckmann, Helen Woodman, and Mark Gaze. "Cancer services for children, teenagers, and young adults." In Radiotherapy and the Cancers of Children, Teenagers, and Young Adults, edited by Tom Boterberg, Karin Dieckmann, and Mark Gaze. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198793076.003.0002.
Full textAbstract:
Chapter 2 discusses cancer services for children, teenagers, and young adults. Paediatric and teenage and young adult practice covers an age range from babies through adolescence to maturity. Oncological services should be age and developmentally appropriate. As cancers in this age group are rare and different from common adult malignancies, specialist treatment should be limited to regional centres with the required expertise. Multidisciplinary teams with diagnostic, therapeutic, and supportive-care expertise are needed. As decision-making can be challenging, wider discussions are sometimes required to select the best treatment option. The aim is to maximize the chance of cure with the fewest late effects. Radiotherapy for children and young people is complex and requires a team approach including specialist radiographers and radiation oncologists, as well as support from paediatric medical, nursing, and anaesthetic staff. Enrolment into clinical trials is the standard of care. Paediatric radiation oncologists should be involved in these trials.
5
Mosher, Pamela J., and Anna C. Muriel. "Depression, anxiety, and delirium." In Oxford Textbook of Palliative Care for Children, edited by Richard Hain, Ann Goldman, Adam Rapoport, and Michelle Meiring. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198821311.003.0024.
Full textAbstract:
The assessment and treatment of psychological disorders such as depression, anxiety, and delirium can prove challenging in paediatric palliative care (PPC). Clinicians face the difficulties of distinguishing among symptoms of disease progression, medical side effects, and ‘normal’ psychological distress; the roles of cognitive and emotional development; and the lack of standardized assessment measures. Because research in this area is limited, recommendations often are extrapolated from adult palliative care (PC), or paediatric psychiatric or psychological literature in populations without life-threatening conditions. Patient- and family-centred care require that we address these symptoms, which may not meet clear diagnostic criteria, but significantly impair quality of life (QOL). Careful history taking, active listening, and close observation are essential in unearthing psychological symptoms. Collaboration with mental health professionals is recommended whenever possible, to provide specialist assessment and inform non-pharmacological and psychopharmacological treatment. Clinicians must incorporate limited data with clinical judgement and consultation to guide interventions that best reduce suffering and improve quality of life.
6
Sherbourne, Karen. "Teenage and young adult cancer." In Oxford Handbook of Cancer Nursing, edited by Mike Tadman, Dave Roberts, and Mark Foulkes. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198701101.003.0035.
Full textAbstract:
There is increasing recognition that teenagers and young adults (TYAs) are a distinct group from children and older adults and have their own unique needs. This chapter explores the particular issues that affect this group, including late diagnosis, psychosocial impact, family concerns, late effects of treatment, and end-of-life care issues. The role of primary treatment centres is discussed. This provides expertise in young persons' cancer and treatment and specialist support, including youth workers, clinical psychologists, and specialist nurses. Nursing support is explored, and helpful hints are given on how to manage and support patients in this group.
7
Pearce, Linda, and Samantha Prigmore. "Understanding Asthma." In Adult Nursing Practice. Oxford University Press, 2012. http://dx.doi.org/10.1093/oso/9780199697410.003.0012.
Full textAbstract:
The aim of this chapter is to provide nurses with the knowledge to be able to assess, manage, and care for people with asthma in an evidence-based and person-centred way. The chapter will provide a comprehensive overview of the causes, risk factors, and impact of asthma, before exploring best practice to deliver care, as well as to prevent or minimize further ill-health. Nursing assessments and priorities are highlighted throughout, and the nursing management of the symptoms and common health problems associated with asthma can be found in Chapters 15 and 22, respectively. In the absence of a standardized definition of asthma, it is accurately described as:…Airway inflammation and hyper-responsiveness characterised by widespread reversible narrowing of the airways, which varies either spontaneously or in response to treatment. (British Thoracic Society/Scottish Intercollegiate Guidelines Network, 2009)…The clinician diagnosis of asthma is based on symptoms, patient history, lung function testing (including peak expiratory flow rate diary), and the demonstration of an efficacious response to a trial of inhaled therapy. An estimated 5.4 million people in the UK are receiving treatment for asthma (Lung and Asthma Information Agency, 2006). In 2006–07, there were 67,077 hospital admissions for asthma in England, over 40% of which were for children under the age of 15 (Asthma UK, 2010). Asthma is estimated to cost the NHS £1 billion per year. With one in five households affected, asthma accounts for at least 12.7 million workdays lost each year (Asthma UK, 2005). In 2008, there were 1,071 deaths in England and Wales due to asthma (Office for National Statistics, 2009). Atopy is a genetically based condition in which individuals have a tendency to hypersensitivity in their reaction to allergens and other triggers. The reaction is usually immediate and localized, and manifests in diseases such as asthma, hay fever, and contact dermatitis. Genetic studies (Holloway et al., 2010) investigating atopy and asthma have shown linkages to many chromosomal locations indicating genetic heterogeneity (having different characteristics and qualities). There is genetic control over the ability to produce significant quantities of immunoglobulin E (IgE), a blood plasma protein that activates allergic reactions by acting as an antibody, when exposed to environmental allergens.
8
Prigmore, Samantha, and Jane Scullion. "Understanding Chronic Obstructive Pulmonary Disease." In Adult Nursing Practice. Oxford University Press, 2012. http://dx.doi.org/10.1093/oso/9780199697410.003.0015.
Full textAbstract:
The aim of this chapter is to provide nurses with the knowledge to be able to assess, manage, and care for people with chronic obstructive pulmonary disease (COPD) in an evidence-based and person-centred way. The chapter will provide a comprehensive overview of the causes, risk factors, and impact of COPD, before exploring best practice to deliver care, as well as to prevent or minimize further ill-health. Nursing assessments and priorities are highlighted throughout, and the nursing management of the symptoms and common health problems associated with COPD can be found in Chapters 2, 15, 18, and 22, respectively. Chronic obstructive pulmonary disease (COPD) is predominantly caused by smoking and is characterized by airflow obstruction that is not fully reversible (National Institute for Health and Clinical Excellence (NICE), 2010). This broad definition embraces previously used definitions such as chronic bronchitis, emphysema, and chronic asthma. Historically, perceptions of the treatment for and care of the patient with COPD were negative, because of the chronic nature of this progressive disease, which was often viewed as self-inflicted through its links with smoking. Current emphasis, regardless of aetiology, is that it is both preventable and treatable (National Institute for Health and Clinical Excellence (NICE), 2010). Currently around 1 million UK citizens are diagnosed with COPD; prevalence data are higher, at 1.7 million (Britton, 2003). This appears to be underreported because it is thought that there could be as many as another 2 million people currently undiagnosed (British Lung Foundation, 2006). COPD is already a significant burden of disease area, with expectations that, by 2020, it will be the third largest cause of mortality (Murray and Lopez, 1997). Reasons for increasing prevalence include that:… ● an ageing population increases the likelihood of chronic disease development; ● diagnosis of COPD is better guided by both national and international COPD guidelines, with inclusion in the Quality and Outcomes Framework (QOF) in general practice bringing financial incentives for maintaining COPD registers and improving COPD care; ● increasing public awareness leads to more people seeking help on symptom presentation; ● more women being diagnosed, correlating to more women smoking, perhaps owing to greater social acceptability; ● other as yet unknown causes....
9
"Emerging Issues in the Emerging Adult Substance Use Field." In Emerging Adults and Substance Use Disorder Treatment, edited by Douglas C. Smith. Oxford University Press, 2017. http://dx.doi.org/10.1093/med-psych/9780190490782.003.0012.
Full textAbstract:
Nearly two decades of research exist that use emerging adulthood as an organizing developmental construct to describe individuals ages 18–29. Yet, much remains to be learned regarding how to best provide effective substance use disorder prevention and treatment services to this population. This chapter argues that emerging adults should be considered a special population worthy of additional research and clinical program development efforts. Additionally, it provides one clinical scientist’s views on priority research and clinical practice areas that may improve substance use disorder treatment and prevention services to emerging adults. These priority research areas include increasing access and retention of emerging adults in substance use treatment, improving the diagnostic classification of substance use problems with emerging adults, monitoring macro-level trends with marijuana and opiate use among emerging adults, and gaining a better understanding of whether developmental constructs thought to be unique to emerging adults predict the onset, course, or treatment response of substance use disorders.
10
Thompson, Paul. "The adult patient." In Oxford Textbook of Rheumatology. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0003.
Full textAbstract:
The adult patient gives the trainee rheumatologist insight into the wide range of musculoskeletal problems faced by our patients, the many different clinical pictures they present, and how their disorders evolve over time. Using clinical vignettes to stimulate thought and evidence-based articles and reviews to underpin the text the chapter covers patients with mono-, oligo-, and polyarthritis, regional soft tissue and myofascial pain, polymyalgia, and systemic autoimmune rheumatological conditions. The importance of disease classification for helping prognosis and treatment strategies is contrasted with the difficulty of fitting many of our patients into a diagnostic pigeon hole. Particular emphasis is placed on the need for the rheumatologist to take a holistic approach to the subject and to remember that outcome depends not only on the disease but also the person affected.
Conference papers on the topic "Adult Diagnostic and Treatment Center"
1
Gupta, Sahil, Rasmi Palassery, Santhosh K. Devadas, Vinayak Maka, and Nalini Kilara. "Epidemiology of Adolescent and Young Adult Cancers in a Tertiary Hospital in South India." In Annual Conference of Indian Society of Medical and Paediatric Oncology (ISMPO). Thieme Medical and Scientific Publishers Pvt. Ltd., 2021. http://dx.doi.org/10.1055/s-0041-1735371.
Full textAbstract:
Abstract Introduction There has been an increase in the incidence of malignancies in young Indians, and there is no data reflecting the trend and profile of adolescent and young adult (AYA) cancers. Objectives This study was aimed to ascertain the epidemiology of AYA cancers in a tertiary care center in south India and the trend of AYA cancers during the past 9 years. Materials and Methods All patients aged 15 to 39 years with the diagnosis of cancer who were registered and received treatment with M.S. Ramaiah Hospital during a 9-year period from January 2011 to December 2019 were included. Basic demographic information on age, gender was available along with address and contact information. Using cancer site and morphology codes, the cancers were grouped by the ICD-O coding system of AYA cancers and their clinical information on disease and treatment status were collected retrospectively and analyzed. Results Of the total 946 registered AYA cancer patients, majority of AYA cancer were in age group of 35 to 39 years (39%) and females (58%). When analyzing the data and dividing the AYA population into early (15–24 years) and late (25–39 years), we found that whereas the majority of the patients had hematolymphoid malignancies (48%) in the early group (15–24 years), the late group (25–39 years) had more carcinomas (68%). The percentage distribution of AYA cancers among the study population, lymphoma and leukemia contribute 11% and 15%, respectively, to the patient load and still the carcinomas formed the bulk (58%) of the population. It is interesting to know that breast, genitourinary, and gastrointestinal (GI) malignancies constituted 17.75%, 14.16%, and 14.69% individually. Conclusion AYA oncology consists of a heterogeneous population and the profile differs by geography, sex, and other factors. There has been limited improvement in the past decade but there is a lot more to be done. To assess the problem, we have to identify and characterize the problem and look at the epidemiology of this population. This will require multicenter and international studies with focus on improving outcomes as in pediatric inspired ALL protocols. The trials should be started at local levels to ensure maximum participation. We need to generate data on epidemiology and channel our resources properly to save this precious but so called lost tribe of oncology.
2
Thrull, Michael, Sebastian Bröckling, Christoph Schliemann, et al. "Diagnostic latency and pulmonary morbidity in adult patients with primary immunodeficiency (PID): A single center experience." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.oa2906.
Full text
3
Buchem, Ilona, Susan Vorwerg, Oskar Stamm, Kristian Hildebrand, and Yvonne Bialek. "Gamification in Mixed-Reality Exergames for Older Adult Patients in a Mobile Immersive Diagnostic Center: A Pilot Study in the BewARe Project." In 2021 7th International Conference of the Immersive Learning Research Network (iLRN). IEEE, 2021. http://dx.doi.org/10.23919/ilrn52045.2021.9459337.
Full text
4
Kondo, T., Y. Okada, A. Shibata, et al. "THU0577 Tocilizumab monotherapy for adult onset still's disease – results of 52-week treatment of a prospective, single-center, single-arm, open trial." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.4922.
Full text
5
Close, Natasha, Julia Dilley, and Janet Baseman. "Poison Center Reports of Cannabis Exposures among Children in Washington State, 2016." In 2020 Virtual Scientific Meeting of the Research Society on Marijuana. Research Society on Marijuana, 2021. http://dx.doi.org/10.26828/cannabis.2021.01.000.20.
Full textAbstract:
Washington State began legal cannabis retail sales in 2014. Legalization of adult use cannabis and retail sales may result in more cannabis products in homes and opportunities for accidental exposures among young children. Consumption of cannabis by young children can result in significant adverse health effects. This study examined details of cannabis exposure events involving children under age 12 that were reported to the Washington State Poison Center (WAPC) during January – December 2016. Redacted charts were obtained from the WAPC “Toxicall” database. 50 eligible events were identified. Structured data were used to describe child age and gender and to obtain information about the involved products, route of administration, exposure setting, and clinical effects. Additional information about the exposure event was available in case notes; qualitative methods were used to develop themes and categorize the cases. Most exposure events (62%) were for children ages 0-2, and 26% were for ages 3-5. None of the exposures were reported as intentional. Of those where the source of the product could be determined (N=29) either a parent (n=20, 69%) or grandparent (n=6, 21%) was the most common source. Nearly all (94%) exposures occurred at the patient’s home and involved a single substance (90%). Of those that noted the type (N=13), 85% indicated that the cannabis was obtained for medical purposes. Most exposures were by ingestion (86%), and edibles were the most often reported form (52% of 41 cases with product specified). Nearly all edibles were brownies, cookies, and candies (96%). Baked goods were reported to be both homemade and purchased. Three cases were exposures to cannabidiol (CBD) among children being treated for seizures by their parents: one was the result of a therapeutic error, one an adverse reaction, and one an unintentional exposure. A single child was reported as exposed through breastmilk. Of those with known medical outcomes (N=33), nearly all caused no or minor clinical effects (78%), and nearly all had symptoms for less than 24 hours, most commonly lethargy and drowsiness (50%), but five children were hospitalized for non-critical care and one child with a history of seizures, who was given CBD oil containing THC, required intensive care and intubation. Risk for accidental exposures to cannabis among young children may be increasing as legal cannabis markets become more common. Although most exposures do not cause long-lasting harms, some children can experience significant harm requiring medical intervention. Caregivers of young children are advised to safely store cannabis products in the home so that they are out of reach of children, and to use caution and consult with a healthcare provider about use of cannabis products for medical treatment of a child or adult use while breastfeeding. Clinicians may play a role by screening for household cannabis use among parents and other caregivers, and advising about safe home practices. Continued regulatory approaches to limit exposure, such as limits on THC potency and single-serving packaging designs, may also be useful.
6
Киреева, Виктория, Viktoriya Kireeva, Ю. Усольцев, et al. "Intermediate results 2016 of a search study of translational diagnostic methods Mitochondrial dysfunction in patients with chronic myocardial ischemia and/or head Brain." In Topical issues of translational medicine: a collection of articles dedicated to the 5th anniversary of the day The creation of a department for biomedical research and technology of the Irkutsk Scientific Center Siberian Branch of RAS. INFRA-M Academic Publishing LLC., 2017. http://dx.doi.org/10.12737/conferencearticle_58be81ec94893.
Full textAbstract:
Purpose of the study. To rate prognostic properties of changes in mitochondrial DNA concentration in the blood plasma of patients with chronic cerebral ischemia and ischemic heart disease in relation to the disease and the effectiveness of the therapy. Materials and methods. The study involved patients suffering from coronary heart disease (CHD) and chronic cerebral ischemia (CCI) with stable and unstable atherosclerotic plaques, who have signed informed consent to the data processing within the framework of scientific research. The patients were admitted to the hospital for examination and treatment of CHD and CCI in Cardiology and Neurology Unit of the Hospital of ISC SB RAS. The subjects underwent laboratory and instrumental examination and analysis of the level of free circulating serum mitochondrial DNA by real-time PCR (copies/ml). The examination results considered as satisfactory were compared with the mtDNA levels before and after the treatment. Results. The average value of the mtDNA levels before and after the treatment in patients of neurological and cardiological profile were significantly different: 1 093 686 copies/ml vs 418 046 copies/ml, respectively (p = 0.02). Unlike women, men mtDNA levels statistically significantly (p = 0.03) decreased after the treatment. We revealed statistically significant differences in mtDNA level indicators before and after the treatment, depending on the definition of the series (p = 0.0010) for rank test Kruskal – Wallis test. The results of the proposed research will help to identify prognostic factors of destabilization of cell damage and plaques in endothelial dysfunction, atherosclerosis and its complications, to conduct clinical test of the method for predicting and diagnostics of cellular damage in chronic ischemia on a background of atherosclerosis.
7
Gopan, Gayatri, Geetha Narayanan, Sreejith G. Nair, et al. "Outcome of Treatment in Elderly Myeloma—A Single-Centre Experience." In Annual Conference of Indian Society of Medical and Paediatric Oncology (ISMPO). Thieme Medical and Scientific Publishers Pvt. Ltd., 2021. http://dx.doi.org/10.1055/s-0041-1735368.
Full textAbstract:
Abstract Introduction Multiple myeloma (MM) accounts for approximately 1% of all cancers and 10% of all hematologic malignancies. In our institution, we see around 200 patients with myeloma every year. We present our experience with multiple myeloma in the patients aged more than 60 years. Objectives This is a retrospective study of 300 newly diagnosed multiple myeloma patients above 60 years of age treated in the Department of Medical Oncology, Regional Cancer Center, Thiruvananthapuram, Kerala, India, during the period between 2014 and 2017. The medical records of the patients were studied and following data were collected: demographic and clinical details, diagnostic and staging workup, primary treatment, response assessment, relapse, and survival. Survival was estimated using the Kaplan–Meier method. Results A total of 300 patients were included in the study. The median age was 66 years with a male-to-female ratio of 1.4:1. The common clinical presentations were backache (134), fatigue (49), lower respiratory infection (20), and paraparesis (14). Monoclonal protein was immunoglobulin (Ig)-G in 199 patients (66.6%), IgA in 52 patients (17.4%), IgM in 2 patients, and IgD in 1 patient. Light-chain disease was seen in 42 patients (14%). One hundred and sixty patients (53.5%) had ISS stage III. Only 285 patients received treatment, of which 203 (67.8%) received bortezomib-based regimen, - bortezomib and dexamethasone (BD; 33.4%); bortezomib, lenalidomide, and dexamethasone (BLD; 19.7%); bortezomib, cyclophosphamide, and dexamethasone (VCD; 8.7%); bortezomib, thalidomide, and dexamethasone (BTD; 2.3%); and bortezomib, melphalan, and prednisolone (3.7%). Nonbortezomib-based regimens used were melphalan and prednisolone (MP) alone or with thalidomide or lenalidomide (15%), lenalidomide and dexamethasone (LD; 10.4%), and thalidomide and dexamethasone (TD; 2%). Response assessment was done as per IMWG guidelines. Fifty-seven (26.3%) patients achieved complete response (CR), 94 (43.3%) achieved very good partial response (VGPR), 19 (8.8%) attained partial response (PR), 15 (5.6%) had stable disease, and 46 (15.4%) developed progressive disease. With bortezomib-based regimens, 119 patients (58.3%) achieved CR/VGPR, and with non-bortezomib based regimens, 42 patients (51.2%) achieved CR/VGPR. One hundred and forty-three patients (47.8%) received maintenance therapy of which 79 received maintenance with bortezomib, 49 with lenalidomide, and 15 with thalidomide. The average duration of maintenance was 24 months. Second-line chemotherapy regimens were used in 37 patients. Agents used were MP, LD, TD, and VCD. With second-line treatment, 15 patients achieved VGPR, 10 patients achieved partial response, and 25 patients developed progressive disease. Third-line chemotherapy regimens were used in 22 patients and the regimens used were pomalidomide and dexamethasone, MP, TD, LD, vincristine, doxorubicin, and dexamethasone and carfilzomib and dexamethasone. At a median follow-up of 34 months, the 2-year overall survival (OS) was 68%. The median progression-free survival was 21 months. The 2-year OS for patients receiving initial bortezomib-based regimen was 67.8% and non-bortezomib based regimen was 68% which was similar. Conclusion In this study, CR/VGPR rates and 2-year OS in patients treated with bortezomib and non-bortezomib based regimens were not statistically significant.
8
Апарцин, Константин, and Konstantin Apartsin. "The results of fundamental and translational research carried out In the Department of Biomedical Research and Technology of the SBRAS INC in 2012-2016." In Topical issues of translational medicine: a collection of articles dedicated to the 5th anniversary of the day The creation of a department for biomedical research and technology of the Irkutsk Scientific Center Siberian Branch of RAS. INFRA-M Academic Publishing LLC., 2017. http://dx.doi.org/10.12737/conferencearticle_58be81eca22ad.
Full textAbstract:
The results of basic and translational research of the Department of Biomedical Research and Technology of Irkutsk Scientific Center of the Siberian Branch of the Russian Academy of Sciences in 2012–2016 The paper presents the results of interdisciplinary research carried out in 2012–2016. The review includes the study of molecular mechanisms of pathogenesis of reparative regeneration, experimental substantiation of methods of diagnosis and prognosis of systemic disturbances of regeneration process, carrying out clinical trials of medicinal products and the formation of observational studies in the field of personalized medicine, the preparation of practical recommendations on the testing of previously developed surgical methods of prevention or correction of postoperative recovery disorders. New data are obtained on the role of the MAP-kinase cascade in the process of regeneration of muscle tissue. It has been established, that with a significant increase of VEGF concentration at the site of the repair of ischemic myocardium, progenitor cells with the CD34+CD45+ phenotype appear, which opens up prospects for the development of biotechnology to restore the damaged myocardium with its own pool of progenitor cells. The new data on the role of growth factors in the post-infarction remodeling are found. It has been revealed, that in local increase of selenium concentration low intensity of mineralization of forming callus in the area of the damage is observed and the formation of bone regeneration slows down. Prospects for the use of nanocomposites of elemental selenium for modulation of reparative response are marked. The dynamics of the level of free circulating mitochondrial DNA (mtDNA) of blood in the early stages of experimental dyslipidemia has been studied. Atherogenic blood factors do not have a significant effect on the release of the mtDNA from dyslipidemia target cells. On the model of acute small-focal myocardial ischemia, we revealed the increase in the mtDNA levels. Prospects of broadcast of diagnostic mtDNA monitoring technology in myocardial ischemia have been marked. The mtDNA monitoring was first tested as a molecular risk pattern in acute coronary syndrome. In survived patients, the concentration of freely circulating mtDNA in blood plasma was 164 times lower. The probability of death of the patient with a high level of mtDNA (over 4000 copies/mL) was 50 % (logit analysis). Methodological level of translational research in the ISC SB RAS has increased due to effective participation in international multi-center clinical trials of drugs, mainly direct anticoagulants: fondaparinux, edoksabana, betriksabana. “Feedback broadcast” of the results of clinical trials of p38-kinase inhibitor, was carried out in the process of changing the model (initially – neuropathic pain) for coronary atherosclerosis. Technologies of pharmacogenetic testing and personalized treatment of diseases in the employees of the Irkutsk Scientific Center were applied. Step T2. Previously developed at the Irkutsk State Medical University and the Irkutsk Scientific Center of Surgery and Traumatologies approaches to surgical prevention and medicinal correction of postoperative hyposplenism were translated into practical health care. Thus, these results obtained in different areas of translational medicine will determine scientific topics of the department in future research cycle.
Reports on the topic "Adult Diagnostic and Treatment Center"
1
Schnabel, Filipina, and Danielle Aldridge. Effectiveness of EHR-Depression Screening Among Adult Diabetics in an Urban Primary Care Clinic. University of Tennessee Health Science Center, 2021. http://dx.doi.org/10.21007/con.dnp.2021.0003.
Full textAbstract:
Background Diabetes mellitus (DM) and depression are important comorbid conditions that can lead to more serious health outcomes. The American Diabetes Association (ADA) supports routine screening for depression as part of standard diabetes management. The PHQ2 and PHQ9 questionnaires are good diagnostic screening tools used for major depressive disorders in Type 2 diabetes mellitus (DM2). This quality improvement study aims to compare the rate of depression screening, treatment, and referral to behavioral health in adult patients with DM2 pre and post-integration of depression screening tools into the electronic health record (EHR). Methods We conducted a retrospective chart review on patients aged 18 years and above with a diagnosis of DM2 and no initial diagnosis of depression or other mental illnesses. Chart reviews included those from 2018 or prior for before integration data and 2020 to present for after integration. Sixty subjects were randomly selected from a pool of 33,695 patients in the clinic with DM2 from the year 2013-2021. Thirty of the patients were prior to the integration of depression screening tools PHQ2 and PHQ9 into the EHR, while the other half were post-integration. The study population ranged from 18-83 years old. Results All subjects (100%) were screened using PHQ2 before integration and after integration. Twenty percent of patients screened had a positive PHQ2 among subjects before integration, while 10% had a positive PHQ2 after integration. Twenty percent of patients were screened with a PHQ9 pre-integration which accounted for 100% of those subjects with a positive PHQ2. However, of the 10% of patients with a positive PHQ2 post-integration, only 6.7 % of subjects were screened, which means not all patients with a positive PHQ2 were adequately screened post-integration. Interestingly, 10% of patients were treated with antidepressants before integration, while none were treated with medications in the post-integration group. There were no referrals made to the behavior team in either group. Conclusion There is no difference between the prevalence of depression screening before or after integration of depression screening tools in the EHR. The study noted that there is a decrease in the treatment using antidepressants after integration. However, other undetermined conditions could have influenced this. Furthermore, not all patients with positive PHQ2 in the after-integration group were screened with PHQ9. The authors are unsure if the integration of the depression screens influenced this change. In both groups, there is no difference between referrals to the behavior team. Implications to Nursing Practice This quality improvement study shows that providers are good at screening their DM2 patients for depression whether the screening tools were incorporated in the EHR or not. However, future studies regarding providers, support staff, and patient convenience relating to accessibility and availability of the tool should be made. Additional issues to consider are documentation reliability, hours of work to scan documents in the chart, risk of documentation getting lost, and the use of paper that requires shredding to comply with privacy.
2
Center for Plant Health Science and Technology Accomplishments, 2007. U.S. Department of Agriculture, Animal and Plant Health Inspection Service, 2008. http://dx.doi.org/10.32747/2008.7296841.aphis.
Full textAbstract:
This past year’s hard work and significant changes have enabled CPHST—a division of the U.S. Department of Agriculture (USDA), APHIS Plant Protection and Quarantine (PPQ) program—to be an organization more capable and better aligned to support and focus on PPQ’s scientific needs. In 2007, CPHST developed the first PPQ strategic plan for CPHST. The plan shows where CPHST is going over the next 5 years, how it is going to get there, and how it will know if it got there or not. Moreover, CPHST plan identifies critical elements of PPQ’s overall strategic plan that must be supported by the science and technology services CPHST provides. The strategic plan was followed by an operational plan, which guarantees that the strategic plan is a living and breathing document. The operational plan identifies the responsibilities and resources needed to accomplish priorities in this fiscal year and measures our progress. CPHST identifies the pathways by which invasive plant pests and weeds can be introduced into the United States. CPHST develops, adapts, and supports technology to detect, identify, and mitigate the impact of invasive organisms. CPHST helps to ensure that the methods, protocols, and equipment used by PPQ field personnel are effective and efficient. All the work of CPHST is identified under one of the five program areas: Agricultural Quarantine Inspection and Port Technology, Molecular Diagnostics and Biotechnology, Response and Recovery Systems Technology, Risk and Pathway Analysis, and Survey Detection and Identification. CPHST scientists are leaders in various fields, including risk assessment, survey and detection, geographic information systems (GIS), molecular diagnostics, biocontrol techniques, methods and treatment, and mass rearing of insects. The following list outlines some of CPHST’s efforts in 2007: Responding to Emergencies, Developing and Supporting Technology for Treatments, Increasing Diagnostic Capacity, and Supporting Trade.