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1

New Jersey. Legislature. Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center. Meeting of the Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center: Testimony regarding the therapy program of the Adult Diagnostic and Treatment Center. The Task Force, 1995.

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2

New Jersey. Legislature. Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center. Report of the Joint Task Force to Study the Adult Diagnostic and Treatment Center. New Jersey State Legislature, Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center, 1995.

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3

New Jersey. Legislature. Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center. Meeting of the Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center: Testimony regarding therapy and programs. The Task Force, 1994.

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4

New Jersey. Legislature. Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center. Meeting of the Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center: Testimony from superintendent and treatment staff : [November 1, 1994, Avenel, New Jersey]. Office of Legislative Services, Public Information Office, Hearing Unit, 1994.

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5

New Jersey. Legislature. Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center. Meeting of the Joint Legislative Task Force to Study the Adult Diagnostic and Treatment Center: Testimony regarding the reorganization of the ADTC therapy program : [February 1, 1995, Woodbridge, New Jersey]. Office of Legislative Services, Public Information Office, Hearing Unit, 1995.

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6

Adult ADHD: Diagnostic assessment and treatment. Springer, 2013.

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7

University of the State of New York. Office of Audit Services. Audit report, Sullivan County, audit of the Sullivan Diagnostic Treatment Center preschool program. University of the State of New York, State Education Dept., Office of Audit Services, 2000.

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8

Brenda, Freishtat, Zoltan Barbara, and Siev Ellen, eds. Perceptual and cognitive dysfunction in the adult stroke patient: A manual for evaluation and treatment. SLACK, 1986.

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9

Selecting effective treatments: A comprehensive, systematic guide to treating adult mental disorders. Jossey-Bass Publishers, 1990.

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10

J.J. Sandra Sandra Kooij. Adult ADHD: Diagnostic Assessment and Treatment. Springer, 2015.

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11

Johnston, MD, Michael, Harold Adams Jr., MD, and Ali Fatemi, MD, MBA. Neurobiology of Disease. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.001.0001.

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Neurobiology of Disease includes nearly 200 brief but substantial survey chapters on all the major disorders of the nervous system in both adults and children from the perspective of cutting edge neurobiology that is relevant to diagnosis and treatment. The chapters are written mostly by clinicians who are experts and thought leaders in their fields, and who are also active participants in clinical and/or basic research. Readers can find information about recent discoveries that are having a clinical impact, as well as reliable information about the new genetic discoveries that are driving diagnosis as well as being targets for therapeutic research. The book’s editors, Michael Johnston at Johns Hopkins and the Kennedy Krieger Institute, and Harold Adams at the University of Iowa, are respected international authorities in pediatric neurology and adult neurology, respectively, with substantial records of teaching and scholarship. Ali Fatemi, who trained in pediatric neurology and neurogenetics at Massachusetts General and is head of the Moser Center for Leukodystrophies, brings expertise in clinical and research neurogenetics to the editorial team.
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12

Jongsma, Arthur E. Jr, Gregory A. Hinrichsen, and Deborah W. Frazer. Older Adult Psychotherapy Treatment Planner, with DSM-5 Updates, 2nd Edition. Wiley & Sons, Incorporated, John, 2014.

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13

Arthur, E. Jr Jongsma, Gregory A. Hinrichsen, and Deborah W. Frazer. Older Adult Psychotherapy Treatment Planner, with DSM-5 Updates, 2nd Edition. Wiley & Sons, Incorporated, John, 2014.

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14

Older Adult Psychotherapy Treatment Planner, with DSM-5 Updates, 2nd Edition. Wiley & Sons, Incorporated, John, 2014.

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15

Embid, Cristina, and Josep M. Montserrat. Obstructive sleep apnea and upper airway resistance syndrome. Edited by Sudhansu Chokroverty, Luigi Ferini-Strambi, and Christopher Kennard. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199682003.003.0016.

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The prevalence of sleep apnea–hypopnea syndrome (SAHS) is about 2–8% in the adult population. A number of studies have shown associations with arterial hypertension, cardiovascular mortality, and traffic accidents. Given this prevalence and the increasing awareness of SAHS in the medical community as well as in the general population, the demand for consultations and diagnostic studies has increased in recent years. Access to diagnostic testing is difficult, however, with long waiting lists. Therefore, there is growing interest in diagnostic methods and approaches involving all levels of the heath system, from primary care to hospital sleep units. This chapter reviews the pathophysiology of the upper airway and how it is possible to measure its disruption in order to diagnose SAHS. It also summarizes clinical implications and overall treatment strategies.
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16

LaHue, Sara, and Morris Levin. Emergency Neurology. 2nd ed. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190064303.001.0001.

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Neurological emergencies, either presenting in the emergency department, arising in hospitalized patients, or presenting in the field are among the most worrisome of all medical situations. Neurologists are trained in best approaches to these emergencies, which include such diverse presentations as severe headache, transient neurologic deficits, altered consciousness and coma, severe vertigo and balance problems, uncontrolled seizures, radicular and facial pain, and posttraumatic conditions. However, as time is often “the enemy” as ER physicians commonly say, diagnostic and treatment dilemmas are particularly challenging in the field of emergency neurology. This volume attempts, as do all the offerings in Oxford University Press’s What Do I Do Now series, to present straightforward but thorough roadmaps for handling the most common and worrisome impasses faced by neurologists and other providers in the topic area. Illustrative cases in cerebrovascular, epileptic, infectious, inflammatory, metabolic, traumatic, neoplastic, and structural conditions are presented with recommendations for best approaches to differential diagnosis, diagnostic testing, and management decision-making in important challenges faced in both adult and pediatric cases. Each case contains a brief summary of key information. The reader is encouraged to imagine the case under discussion, formulate a differential diagnosis, plan diagnostic testing, and begin thinking about best management approaches. Then read Drs. LaHue’s and Levin’s approach to the situation. At the end of each chapter is a list of key points to remember in the topic and a selection of resources for further reading.
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17

Fye, W. Bruce. Beyond Mid-Century. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199982356.003.0012.

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Specialization in medicine grew in popularity after World War II when federal grants stimulated research into organ-specific diseases and the development of new diagnostic and treatment technologies. Mayo Clinic’s time-honored model of care involved having every internal medicine specialist devote significant time to general diagnosis. Mayo’s cardiologists produced a strategic plan in 1964 in which they expressed concern that this philosophy compromised their role as heart specialists. In 1965 Mayo’s internal medicine training program came under fire from a national group that insisted that it conform to the standard academic medical center model. This resulted in the creation of a Department of Medicine, which reduced the autonomy and influence of subspecialty sections such as cardiology. In 1969 Mayo decided to seek philanthropic support to help launch a medical school and to support its research and training programs. Despite Mayo’s changing structure, its main focus remained patient care rather than research.
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18

Doss, Julia L., and Jeffrey Mark Robbins. The Roles of the Patient and Family. Edited by Barbara A. Dworetzky and Gaston C. Baslet. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190265045.003.0016.

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Psychogenic nonepileptic seizures (PNES) is a complicated disorder to both diagnose and treat. While challenging to manage, the physical symptoms represent only a part of the treatment of PNES. This chapter addresses how to approach the family and the patient from the first diagnostic encounter to the evolving process of outpatient treatment. In addition, working with pediatric and adult patients differs significantly. Pediatric patients with PNES must develop tools for improved management of their symptoms first and then proceed to working on underlying stressors. For adult patients, making the connection between symptoms and underlying stressors is an ongoing process that is woven throughout the course of treatment. Both an adult and a child case are presented to further illustrate these dynamics.
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19

Tejerina, Eva, and Andrés Esteban. Post-mortem examination in the ICU. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0391.

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Autopsy has long been regarded as a valuable and reliable tool to improve quality of medical care by monitoring diagnostic accuracy and treatment of the critically-ill patients. However, post-mortem examination rates have fallen worldwide during the past decades. Unexpected findings at autopsy contribute to the increasing pool of medical knowledge and may allow the development of strategies for the early detection of diagnoses, leading to better patient care. Several studies have shown that major discrepancies are frequent, and in 5–40% of all hospitalized patients, and in 7–32% of adult intensive care patients a treatable condition that might have altered outcome, had it been recognized, is identified at post-mortem examination. Despite technological improvements in medicine, the percentage of missed diagnoses had not changed over time. Autopsy provides a ‘gold standard’ to assess the accuracy of diagnostic tests and also offers relevant information for the advance of medical knowledge and the description of new disease entities. The health care system as a whole can benefit enormously from autopsy data, the autopsy providing information unavailable by any other method, and should be considered in every patient who dies in the intensive care unit.
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20

Viscardi, Rose M., and Ken B. Waites. Ureaplasma urealyticum and Ureaplasma parvum. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190604813.003.0022.

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The Mycoplasma species Ureaplasma parvum and Ureaplasma urealyticum colonize the human adult urogenital tract and are not typically associated with disease. Perinatal transmission, however, has been implicated in the pathogenesis of preterm birth, chorioamnionitis, and other complications of extreme prematurity, including neonatal pneumonitis, bronchopulmonary dysplasia (BPD), meningitis, and necrotizing enterocolitis (NEC). This chapter reviews the biology of these organisms. Epidemiologic and experimental evidence supporting a role for ureaplasmas in the pathogenesis of neonatal disease, clinical manifestations of infection in the infant, current microbiologic diagnostic methods, and the present status of treatment options are reviewed. Macrolide antibiotic therapy is controversial for infected infants, and current concepts regarding candidates for treatment are discussed. Key unanswered questions that need to be addressed in future research studies are also suggested.
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21

Daley, Dennis C., and Antoine B. Douaihy. Managing Substance Use Disorder. Oxford University Press, 2019. http://dx.doi.org/10.1093/med-psych/9780190926717.001.0001.

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This practitioner guide reviews screening, assessment, and treatment of substance use disorders (SUDs). It is designed to accompany Managing Your Substance Use Disorder: Client Workbook and A Family Guide to Coping with Substance Use Disorders. The latter guide was added because each person with a SUD affects the family and concerned significant others. The information and strategies that the authors present can be used with clients who have any type of SUD. The guide focuses on strategies to reduce or stop substance use and change behaviors that challenge recovery. The information presented is derived from research, clinical, and recovery literature and from the authors’ extensive experience developing and managing a large continuum of clinical services, providing direct care, conducting quality improvement initiatives, participating in clinical trials, and teaching all disciplines in a large medical center and the community. This guide discusses professional approaches and attitudes toward individuals with SUDs, assessment, diagnostic formulation, psychosocial and pharmacotherapeutic treatments, and mutual support programs. It provides an overview of the recovery and relapse processes and practical strategies to address issues associated with SUDs. This guide is for practitioners from any discipline who encounter individuals with SUDs in addiction, mental health, psychiatric, private practice, or other settings such as social services and the criminal justice system. Even medical practitioners who do not specialize in addiction treatment can benefit from the information in this guide because individuals with SUDs are found in all types of healthcare settings.
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22

Hamblin, Rebecca J., Jennifer Moonjung Park, Monica S. Wu, and Eric A. Storch. Variable Insight in OCD. Edited by Christopher Pittenger. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228163.003.0013.

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Individuals with obsessive-compulsive disorder (OCD) often have good insight into the irrational nature of their obsessions and the excessive character of their compulsions, but insight exists along a continuum and is markedly poor in some patients. This chapter reviews the assessment and phenomenological correlates of variable insight in OCD in both pediatric and adult populations. It reviews the definition of insight and its relationship to the evolution of diagnostic criteria for obsessive-compulsive disorder, as well as the major assessment tools used to measure and quantify insight for clinical and research purposes. The relationships between insight and clinical characteristics of OCD, including symptom severity, comorbidity, and treatment response are reviewed, followed by a review of neurobiological correlates of insight and the relationship between poor insight and schizophrenia spectrum disorders.
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23

Hjalgrim, Henrik, Ellen T. Chang, and Sally L. Glaser. Hodgkin Lymphoma. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0039.

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Hodgkin lymphoma (HL) is a malignant neoplasm of the lymphatic system. The malignant cell clone derives from germinal center B lymphocytes in ~98% of cases, the rest being of T-lymphocyte origin. Each year, HL is diagnosed in roughly 66,000 individuals worldwide. HL is curable with modern therapy in the vast majority of patients, with five-year survival rates exceeding 90% for early-stage disease. However, so far this excellent prognosis has been achieved at the expense of a high incidence of severe long-term treatment complications such as secondary malignancies, and endocrine and cardiovascular diseases. In affluent Western countries, HL occurrence follows a distinctive and unusual bimodal age distribution, with one incidence peak among adolescents and younger adults and another in older adults. In socioeconomically less affluent populations, in contrast, the adolescent and younger-adult incidence peak is less pronounced, whereas incidence of HL in young boys may be higher than in affluent populations.
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