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Journal articles on the topic 'Advanced-aged elderly'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Lee, Bora, Seung Min Park, Jisun Huh, et al. "The Necessity of Establishing a Specialist Program for Geriatric Dentistry for the Elderly of Korea Based on their General Health Status." Journal of The Korean Dental Association 57, no. 10 (2019): 579–87. http://dx.doi.org/10.22974/jkda.2019.57.10.003.

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Korea became an aged society as of 2018, and will have plunged into a super-aged society by 2025. For the dental treatment of elderly patients, their general conditions are to be considered to make appropriate treatment plans and strategies, based on advanced knowledge of geriatric dentistry and clinical experience. In this study, the social demand for geriatric dental specialists for the treatment of the elderly of Korea is investigated by looking at their general health conditions, ADL (Activities of Daily Living), and IADL (Instrumental Activities of Daily Living), along with the review of

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Meng, Zhaojun, and Yujuan He. "Exploration of Theoretical Dimensions and Practical Pathways for Medical Social Work Intervention in Elderly Care Services for The Advanced-Aged Under the Background of Active Aging." International Journal of Social Science and Human Research 08, no. 05 (2025): 2805–11. https://doi.org/10.5281/zenodo.15355074.

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With the accelerating process of population aging, the demand for elderly care services has surged dramatically. Proactively addressing population aging and promoting the high-quality development of aging-related initiatives and industries are not only inherent requirements for building a socialist active aging society with Chinese characteristics in the new era but also a crucial driver for comprehensively optimizing elderly care services in both urban and rural areas. From the perspective of active aging, this study analyzes the theoretical dimensions of medical social work intervention in e

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Biryukova, Elena V. "Type 2 diabetes mellitus in elderly patients treated with endocrinologists in clinical practice." Diabetes mellitus 22, no. 6 (2020): 582–91. http://dx.doi.org/10.14341/dm10315.

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A large-scale epidemic of type 2 diabetes mellitus (T2DM) is observed with advanced ageing worldwide. The prevalence of T2DM significantly increases with age. Therefore, this review aimed to summarise the data on T2DM in advanced and older aged patients. The primary geriatric syndromes, which should be considered for the management of older patients (cognitive impairment, sarcopenia, orthostatic hypotension, falls, urinary incontinence, senile asthenia, etc.), are presented. The causes of the high risk for hypoglycaemia in elderly patients are analysed. Improving the treatment for T2DM is a pr

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Hiriscau, Elisabeta Ioana, Elena-Cristina Buzdugan, Ligia-Ancuta Hui, and Constantin Bodolea. "Exploring the Relationship between Frailty, Functional Status, Polypharmacy, and Quality of Life in Elderly and Middle-Aged Patients with Cardiovascular Diseases: A One-Year Follow-Up Study." International Journal of Environmental Research and Public Health 19, no. 4 (2022): 2286. http://dx.doi.org/10.3390/ijerph19042286.

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The association between frailty, disability in activities of daily living (ADL), polypharmacy, and quality of life (QoL) in middle-aged patients with cardiovascular disease (CVD) is little investigated. This study sought (a) to explore this association comparatively in elderly and middle-aged hospitalized patients with CVD and (b) to determine which domains of ADL and QoL might improve the frailty prediction. A one-year follow-up study including 90 elderly (≥65 years old) and 89 middle-aged patients (40–65 years old) was conducted. At baseline, frailty assessment was performed based on the Fri

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Liu, Xiao-Li, and Lun-Lan Li. "Survey on hospice care attitude of family members of advanced cancer patients at different ages." World Journal of Clinical Cases 12, no. 21 (2024): 4626–31. http://dx.doi.org/10.12998/wjcc.v12.i21.4626.

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BACKGROUND Hospice care plays an important role in improving the quality of life of advanced cancer patients, but controversy remains over whether age affects the attitudes of family members toward hospice care. AIM To investigate the attitudes of family members of advanced cancer patients of different ages toward hospice care. METHODS The study participants were 175 family members of patients with advanced cancer from January 2020 and October 2022. The participants were divided into youth (< 40 years, n = 65), middle-aged (40–60 years, n = 59), and elderly (> 60 years, n = 51) groups. R

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Joyce, Evan, Michael T. Bounajem, Jonathan Scoville, et al. "Middle meningeal artery embolization treatment of nonacute subdural hematomas in the elderly: a multiinstitutional experience of 151 cases." Neurosurgical Focus 49, no. 4 (2020): E5. http://dx.doi.org/10.3171/2020.7.focus20518.

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OBJECTIVEThe incidence of already common chronic subdural hematomas (CSDHs) and other nonacute subdural hematomas (NASHs) in the elderly is expected to rise as the population ages over the coming decades. Surgical management is associated with recurrence and exposes elderly patients to perioperative and operative risks. Middle meningeal artery (MMA) embolization offers the potential for a minimally invasive, less morbid treatment in this age group. The clinical and radiographic outcomes after MMA embolization treatment for NASHs have not been adequately described in elderly patients. In this p

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Sabha, Madieha, and Khushbu Bashir. "Fertility, conception and complications in elderly primigravidas a comparative study: observational study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 12, no. 7 (2023): 2119–22. http://dx.doi.org/10.18203/2320-1770.ijrcog20231920.

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Background: Incidence of elderly primigravida has increased now days, due to rising education level, effective means of birth control and high carrier goals. The women who conceived at advanced age (>35 years) for first time is defined as elderly primigravida. Indian standard is fixed at more than 30 years by Dutta 2013. These women are high risk for maternal and foetal complication and outcome. The study was done to assess pregnancy outcome in elderly primigravida. Methods: This was a prospective comparative study done in 180 patients over a period of 18 months from September 2017 to March

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Zhou, Zhi, and Yanchun Wang. "Analysis of the Treatment for Advanced Microsatellite Stable Colorectal Cancer in Middle-Aged and Elderly People." Oncology Treatment Discovery 2, no. 1 (2024): 17–22. http://dx.doi.org/10.26689/otd.v2i1.6374.

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Microsatellite stabilized (MSS) rectal cancer is a highly prevalent cancer in the middle-aged and elderly population. There exists some expertise in detecting and evaluating the chemotherapy effect in advanced colorectal cancer patients. Multiple studies have combined targeted therapy, chemotherapy, and immunotherapy as a breakthrough. Programmed cell death protein 1 (PD-1) inhibitors have certain therapeutic effects in the treatment of MSS rectal cancer patients. The combination of PD-1 inhibitors and furoquinib can improve the disease control rate (DCR) and progression- free survival (PFS) i

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Sheng Li, Yuchen Yin, and Marzudi Md Yunus. "Elderly People in the Digital Cultural Environment: Social media use, environmental stress, and intergenerational interaction." Environment-Behaviour Proceedings Journal 10, no. 31 (2025): 433–39. https://doi.org/10.21834/e-bpj.v10i31.6643.

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Digitalization and population aging are profoundly reshaping contemporary Chinese society, with 14.3% of internet users now aged 60 and above. This study examines elderly Chinese individuals' adaptation to the digital environment through a survey of 205 participants aged 60 and above. Findings reveal widespread basic digital usage (88.78% use smartphones) but limited advanced engagement. While intergenerational support is the primary learning channel (87.32%), significant barriers exist, including communication difficulties and psychological concerns. Digital services' age-friendliness (satisf

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Oba, A., Y. H. A. Wu, C. H. Lieu, et al. "Outcome of neoadjuvant treatment for pancreatic cancer in elderly patients: comparative, observational cohort study." British Journal of Surgery 108, no. 8 (2021): 976–82. http://dx.doi.org/10.1093/bjs/znab092.

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Abstract Background Use of neoadjuvant therapy for elderly patients with pancreatic cancer has been debatable. With FOLFIRINOX (folinic acid, 5-fluorouracil, irinotecan, oxaliplatin) or gemcitabine plus nab-paclitaxel (GnP) showing tremendous effects in improving the overall survival of patients with borderline resectable and locally advanced pancreatic cancer, there is no definitive consensus regarding the use of this regimen in the elderly. Methods This study evaluated the eligibility of elderly patients with borderline resectable or locally advanced pancreatic cancer for neoadjuvant therapy

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Dai, Huiying, and Pooja Solanki. "Leveraging Artificial Neural Networks for Mining Nursing Talents in Elderly Care." International Journal of Healthcare Information Systems and Informatics 19, no. 1 (2024): 1–14. https://doi.org/10.4018/ijhisi.363591.

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As the elderly population continues to grow, there is an increasing demand for specialized nursing care. This paper presents a study focusing on the data mining of nursing talents for the elderly utilizing artificial neural network (ANN) technology. By leveraging advanced data analysis, the research aims to optimize nursing talent allocation and utilization in aged care facilities. Through comprehensive analysis of nursing skills, experience, and patient care outcomes, this study provides data-driven insights and predictive modeling to enhance the administration of nursing talents. The finding

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Goto, Shigeru, Toshiaki Nakano, Chao-Long Chen, King-Wah Chiu, Li-Wen Hsu, and Seiko I. "Application of Artificial Sunlight for the Elderly as a Possible Environmental Nursing Practice." POJ Nursing Practice & Research | Volume 2- Issue 1 – 2018 2, no. 1 (2018): 1–5. http://dx.doi.org/10.32648/2577-9516/2/1/002.

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Aging and aged societies have arrived in many countries where significant development of medicine and the economy has been achieved. Japan is a highly aged society with a shortage of carers both at home and in long-term care settings. In fact, more persons of advanced age who do not need intensive care in hospitals strongly desire health care to be delivered in their own home with their family. Environmental nursing practice, which means that nurses improve the environment of patients or the elderly properly in accordance with healthcare considerations, is currently playing a more important ro

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임안나 and 박영숙. "Effects of Advanced Middle-Aged People's Life Satisfaction on Elderly Life Commencement Age Awareness." Korean Journal of Local Government & Administration Studies 29, no. 3 (2015): 349–64. http://dx.doi.org/10.18398/kjlgas.2015.29.3.349.

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Hata, Masaharu. "Radiation therapy for elderly patients with uterine cervical cancer: feasibility of curative treatment." International Journal of Gynecologic Cancer 29, no. 3 (2019): 622–29. http://dx.doi.org/10.1136/ijgc-2018-000077.

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As the average lifespan lengthens worldwide, and the older adult population increases, the number of elderly patients with uterine cervical cancer is increasing. Because intensive and invasive treatments, including surgery, are frequently unacceptable in elderly patients, cancer treatments for these patients must be carefully considered. Elderly patients have undergone radiation therapy as less-invasive curative treatment, and it has been shown to be safe and effective for local control of cervical cancer in this population, even among patients aged ≥80 years treated with curative radiation do

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Vitale, Carolina, Antonio Galderisi, Angelantonio Maglio, et al. "Diagnostic yield and safety of C-TBNA in elderly patients with lung cancer." Open Medicine 11, no. 1 (2016): 477–81. http://dx.doi.org/10.1515/med-2016-0084.

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AbstractConventional transbronchial needle aspiration (C-TBNA) is a minimally invasive technique used primarily in the diagnosis and staging of lung cancer. Currently lung cancer is mostly considered a disease of the elderly and the management of this disease in older patients is a growing concern.In this study we aimed to assess the diagnostic yield and safety of C-TBNA in elderly patients.A retrospective review of 88 consecutive C-TBNA procedures for nodal staging in suspected or confirmed primary lung cancer or pathological confirmation in suspected advanced lung cancer was performed. Patie

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Amin, Fiza, Tavseef Ahmad Tali, Rifat Ara, and Huda Amin. "Maternal age and pregnancy outcomes in elderly mothers." International Journal of Research in Medical Sciences 11, no. 9 (2023): 3373–75. http://dx.doi.org/10.18203/2320-6012.ijrms20232795.

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Background: Aim of the study was to compare pregnancy outcomes between women aged 40 or older and those aged 20 to 39 years. Methods: The retrospective cohort study was conducted at SKIMS medical college, Srinagar between March 2020 to April 2022 in which hospital records of 170 patients who delivered during the study period were analysed. Results: Among patients of 40 years old and above, obstetric complications are significantly more frequent, with an increased risk of gestational diabetes, pre-eclampsia, gestational hypertension and caesarean delivery. Fetal risk of IUGR, prematurity was si

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Park, Hee-Jung, Ji Yong Ahn, Hwoon-Yong JUNG, et al. "Clinical characteristics and outcomes for gastric cancer patients over age 80: A retrospective case-control study." Journal of Clinical Oncology 33, no. 3_suppl (2015): 30. http://dx.doi.org/10.1200/jco.2015.33.3_suppl.30.

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30 Background: The average human life expectancy is increasing worldwide, thus proportion of elderly gastric cancer patients are also increasing. In this study, we investigated the clinical and oncologic outcomes of gastric cancer in patients over 80 years old through a case-control study. Methods: From January 2004 to December 2010, 291 patients aged over 81 years old (case group) were diagnosed and treated with gastric cancer at the Asan Medical Center. During the same period, 291 patients aged 18 to 80 years old were selected as control group. The clinical findings, histopathological parame

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Ikawa, Fusao, Nobuaki Michihata, Soichi Oya, Hideo Yasunaga, and Nobutaka Horie. "Surgical Risk in Elderly Patients with Meningiomas in Japan." Journal of Clinical Medicine 13, no. 10 (2024): 2882. http://dx.doi.org/10.3390/jcm13102882.

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Background/Objective: No guidelines indicate surgical risk factors for the elderly because of the lack of data from general neurosurgeons. To better understand the management of surgical risk in elderly patients with meningiomas based on a national database in Japan. Methods: Results of surgically treated meningiomas were explored in 8138 patients registered in the Diagnosis Procedure Combination database in Japan during 2010–2015. Age (<65, 65–74, and ≥75 years), sex, Barthel index (BI), medical history, tumor location, oral medication prescriptions on admission, and stroke complications w

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Sabin, Huda. "Robotic Solutions, Usefulness & Obstacles in Elderly Care [Part I: The Developed Nations]." Research and Reviews: Advancement in Robotics 4, no. 3 (2022): 1–8. https://doi.org/10.5281/zenodo.5833187.

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<em>As a blessing of better and advanced medical consciousness, today there is rise in life anticipation. Again this pandemic situation has pinpointed the crucial fact of prioritizing the medical and health services in every respect, especially for the most helpless citizens of our society, the elderly inhabitants. This study perceives assistive robotic use, thus the Healthcare Robots to be a good solution to the problems of the aged which can be achieved through implementing assistive technology and artificial intelligence in the healthcare sector. Research works in many developed nations are

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Hiramatsu, Makoto. "Improving Outcome in Geriatric Peritoneal Dialysis Patients." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 23, no. 2_suppl (2003): 84–89. http://dx.doi.org/10.1177/089686080302302s18.

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Objective Few data are available about elderly patients on peritoneal dialysis (PD). In the present study, we reviewed our experience with patients aged 70 years or more at the start of peritoneal dialysis (PD). Design This retrospective study was conducted at a single center in Japan. Patients and Methods Of 222 patients managed using PD at our hospital between 1991 and 2001 (including 219 cases of PD first), 150 patients were aged under 70 years and 72 patients were 70 years of age or older. For the two groups of patients, we determined clinical data, erythropoietin and PD prescriptions, rea

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Yamashita, Daisuke, Victoria Flanary, Shinobu Yamaguchi, et al. "CBMS-01 Mechanism of brain tumor malignancy caused by aging and social isolation." Neuro-Oncology Advances 2, Supplement_3 (2020): ii3. http://dx.doi.org/10.1093/noajnl/vdaa143.013.

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Abstract The rise in population aging worldwide is causing an unparalleled increase in death from many cancers, including glioblastoma (GBM). In advanced countries, the number of elderly people living alone is increasing due to the rapid aging of the population and the socialization of nuclear families. Here, we explored the impact of aging and social isolation on GBM tumorigenesis. In normal brain tissue, aging promoted pathways related to cytokines and inflammation, which were further promoted by social isolation. In tumor tissues, the expression of neuron/synapse-related genes was significa

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Zheng, Fang, Xiaojing Tang, and Xinyue Zhang. "Analysis of Daily Life, Spiritual Comfort, and Fall Safety Care Needs of Elderly People in Urban and Rural Areas." Journal of Clinical and Nursing Research 9, no. 1 (2025): 157–63. https://doi.org/10.26689/jcnr.v9i1.9497.

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Objective: To examine the daily life care, spiritual comfort, and fall safety care needs of the elderly in urban and rural areas of Tangshan, along with their influencing factors. Methods: From August 2022 to April 2023, an investigation was conducted among urban and rural elderly individuals aged over 75 years in Tangshan City using the Activities of Daily Living Scale, the Revised Community Elderly Fall Risk Assessment Tool, and the Loneliness Scale. Results: The study included 750 urban and 740 rural elderly individuals aged over 75 years. Matrix analysis revealed a significant proportion o

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Kwak, Yeunhee, Yoonjung Kim, and Haekyung Chung. "Sex-Associated Differences in the Handgrip Strength of Elderly Individuals." Western Journal of Nursing Research 42, no. 4 (2019): 262–68. http://dx.doi.org/10.1177/0193945919856304.

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This study aimed to identify sex-specific factors associated with handgrip strength in elderly individuals. The analysis cohort comprised 1,197 men and 1,384 women aged ≥65 years. In men, factors associated with low handgrip strength included advanced age; low body mass index; low frequency of performing flexibility exercises; limited self-care ability (which is a measure of the health-related quality of life); and the presence of diabetes, stroke, or osteoporosis ( R² = 0.285, F = 7.52, p < .001). In women, the factors included advanced age, low body mass index, low frequency of performing

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Roberts, Anjeanette, Christopher Paddock, Leatrice Vogel, Emily Butler, Sherif Zaki, and Kanta Subbarao. "Aged BALB/c Mice as a Model for Increased Severity of Severe Acute Respiratory Syndrome in Elderly Humans." Journal of Virology 79, no. 9 (2005): 5833–38. http://dx.doi.org/10.1128/jvi.79.9.5833-5838.2005.

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ABSTRACT Advanced age has repeatedly been identified as an independent correlate of adverse outcome and a predictor of mortality in cases of severe acute respiratory syndrome (SARS). SARS-associated mortality may exceed 50% for persons aged 60 years or older. Heightened susceptibility of the elderly to severe SARS and the ability of SARS coronavirus to replicate in mice led us to examine whether aged mice might be susceptible to disease. We report here that viral replication in aged mice was associated with clinical illness and pneumonia, demonstrating an age-related susceptibility to SARS dis

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Pompii, O. O., and E. S. Pompii. "ANALYSIS OF THE PREVALENCE AND STRUCTURE OF PERIODONTAL TISSUE DISEASES AMONG ELDERLY PEOPLE IN THE RIVNE REGION." Ukrainian Dental Almanac, no. 4 (December 25, 2024): 28–32. https://doi.org/10.31718/2409-0255.4.2024.05.

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The article presents the results of a survey of elderly residents in the Rivne region to determine the prevalence of periodontal diseases. Objective. To analyze the prevalence and structure of periodontal tissue diseases among elderly patients in the Rivne region. Materials and methods. A total of 500 individuals aged 60 to 75 were examined and divided into three age groups: group I included 183 individuals aged 60-64, group II consisted of 153 patients aged 65-69, and group III included 164 residents aged 70-75. All participants underwent clinical and radiological examinations, and a clinical

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Mattioli, R., L. Imperatori, V. Casdei, et al. "Efficacy and safety of vinorelbine in elderly patients (aged > 70 years) with advanced NSCLC." Lung Cancer 21 (September 1998): S50. http://dx.doi.org/10.1016/s0169-5002(98)90122-2.

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Shweta Sharma, Shishram Saini, Rizwana Shaheen, Asmita Arun, Neetu Gehlot, and Kirti Gupta. "Study of fetal and maternal outcome and associated risk factors in elderly primigravida pregnant women at tertiary care center in Western Rajasthan." Asian Journal of Medical Sciences 16, no. 5 (2025): 66–70. https://doi.org/10.71152/ajms.v16i5.4451.

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Background: Elderly primigravida is one aged 35 or more at first delivery. Elderly primigravida combines the concerns of advanced maternal age with those of obstetrically untested primigravida. While the risks related to multiple pregnancy and previous pregnancy are not applicable, there is an added dimension of precious pregnancy reflecting concern this pregnancy maybe the one and only opportunity to have a child. Aims and Objectives: The aims and objectives of the study are to determine antenatal complications among elderly primigravida woman and maternal and fetal outcome associated with pr

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L, Atroune. "Pituitary Adenoma in the Elderly." Neuroscience and Neurological Surgery 8, no. 05 (2021): 01–07. http://dx.doi.org/10.31579/2578-8868/168.

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Given advances and wide availability of neuroimaging coupled with longer life span, higher numbers of elderly patients with pituitary adenomas are being seen who are potential surgical or medical therapy candidates. Our study concerns 07 cases of Pituitary adenoma in patients aged more than 70 years old, collected in Mustapha Pasha’s neurosurgery department in Algiers for a period of 18 years (from 2000 to 2018). Pituitary adenoma is not considered a disease of advanced age; its incidence is rated around 3–4%. The average age of patients was 72 years old, slightly more common in females and re

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Pegu, Bhabani, and Bhanu Pratap Singh Gaur. "Elderly primigravida and a comparative analysis of their pregnancy outcome with younger primigravida." International Journal of Research in Medical Sciences 6, no. 11 (2018): 3478. http://dx.doi.org/10.18203/2320-6012.ijrms20184402.

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Background: Though pregnancy and child birth is a normal physiological process but a woman with advanced age is a risk factor for adverse pregnancy outcome. This study was conducted to find out the proportion of elderly primigravida and to compare their pregnancy outcome with that in younger primigravida of aged 20-25yrs.Methods: A retrospective study was carried out over a period of two years in a tertiary care hospital of Meghalaya. Secondary data on obstetrics outcome of 54 elderly primigravida aged ≥35 years (study group) was compared to 120 younger primigravida (control group) of aged 20-

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Ploylearmsang, Chanuttha, Chutamat Somboon, Utoomporn Namdee, and Saithip Suttiruksa. "Managing health care needs of the elderly through an elderly care manager: Thailand." F1000Research 11 (June 21, 2022): 680. http://dx.doi.org/10.12688/f1000research.122555.1.

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Background: This mixed method research aimed to investigate health needs of older people and the attributes of the Elderly Care Managers (ECMs), and to evaluate the outcomes of two ECMs coordination. Methods: Three phases were: 1) a field survey of the health needs of 94 older persons; 2) group discussions between ten relevant persons involved in ECMs characteristics; 3) two ECMs coordinating with health-related agencies and measuring the outcomes of older people who needed assistance. Results: 63.1% of the participants had difficulties with their health, 12.8% of them had no caregiver, 26.6%

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Shia, Ben-Chang, Lei Qin, Kuan-Chou Lin, et al. "Outcomes for Elderly Patients Aged 70 to 80 Years or Older with Locally Advanced Oral Cavity Squamous Cell Carcinoma: A Propensity Score–Matched, Nationwide, Oldest Old Patient–Based Cohort Study." Cancers 12, no. 2 (2020): 258. http://dx.doi.org/10.3390/cancers12020258.

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Purpose: Although clinicians encounter patients aged ≥70 years with locally advanced oral cavity squamous cell carcinoma (LA-OCSCC), no evidence is available to facilitate decision making regarding treatment for this elderly population. Methods: We selected elderly (≥70 years) patients from the Taiwan Cancer Registry database who had received a diagnosis of LA-OCSCC. Propensity score matching was performed. Cox proportional hazards model curves were used to analyze all-cause mortality in patients in different age groups receiving different treatments. Results: The matching process yielded a fi

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Shiba, Takahiko, Daisuke Sasaki, Juanna Xie, Chia-Yu Chen, Hiroyuki Tanaka, and Shigemi Nagai. "Association Between Mastication Pattern, Periodontal Condition, and Cognitive Condition—Investigation Using Large Database of Japanese Universal Healthcare System." Big Data and Cognitive Computing 9, no. 2 (2025): 43. https://doi.org/10.3390/bdcc9020043.

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The decline in oral health commonly occurs as a natural consequence of aging or due to various pathological factors. Tooth loss, which diminishes masticatory ability, has been associated with negative impacts on cognitive function. This observational study analyzed dental and medical records from Japan’s Universal Healthcare System (UHCS) national database to investigate the relationship between cognitive and oral disorders, focusing on periodontitis and decreased tooth-to-tooth contact between the maxillary and mandibular arches. A descriptive data analysis evaluated diagnostic codes for Alzh

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Kontola, K., P. Oksanen, H. Huhtala, I. Helavirta, and T. Ilus. "DOP011 Colectomy rates of newly diagnosed Finnish Ulcerative Colitis patients are decreasing." Journal of Crohn's and Colitis 19, Supplement_1 (2025): i101. https://doi.org/10.1093/ecco-jcc/jjae190.0050.

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Abstract Background The effect of biological medication on colectomies is still unclear. Our aim was to determine colectomy risk in newly diagnosed Finnish ulcerative colitis (UC) patients and compare the risk of prebiological and biological era. Methods We used the registry of Social Insurance Institution of Finland to find newly diagnosed UC patients. Data on colectomies were collected from the Finnish Institute for Health and Welfare. Patients were stratified according to the UC diagnosis year and the availability of biological medication in Finland to three groups: 2000-2005 (prebiological

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Hukkinen, Tanja, Tobias Olenius, Selja Koskensalo, Anna Lepistö, Laura Koskenvuo, and Camilla Böckelman. "Short- and Long-Term Survival among Elderly Colorectal Cancer Patients in Finland, 2006–2015: A Nationwide Population-Based Registry Study." Cancers 16, no. 1 (2023): 135. http://dx.doi.org/10.3390/cancers16010135.

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This population-based registry study aimed to report 30-day and one-year postoperative survival, five-year overall survival (OS), and disease-specific survival (DSS) among elderly (≥75 years old) colorectal cancer (CRC) patients. All new colorectal cancer cases from 2006–2015 were included and followed until death or the end of follow-up (end of 2016). Among 27,088 CRC patients, 11,306 patients were ≥75 years old. Among patients ≥ 75 years, 36.8% (n = 4160) had right-sided colon cancer, 21.9% (n = 2478) left-sided colon cancer, and 32.3% (n = 3650) rectal cancer. In this study population, 932

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Riseberg, David. "Treating Elderly Patients with Hormone Receptor–Positive Advanced Breast Cancer." Clinical Medicine Insights: Oncology 9 (January 2015): CMO.S26067. http://dx.doi.org/10.4137/cmo.s26067.

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As the overall population ages, the proportion of elderly patients (aged ≥65 years) with breast cancer also increases. Studies have shown that elderly patients with hormone receptor–positive breast cancer can derive as much benefit from treatment as do younger patients, yet they remain underrepresented in clinical trials and are often undertreated in clinical practice. Treatment decisions for older patients should not be based solely on chronologic age; a patient's physiologic functioning and comorbidities must also be taken into consideration. For recurrent or metastatic disease, systemic tre

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Mulroy, Eoin, and Luciana Pelosi. "079 Nerve ultrasound cross sectional area does not correlate with electrodiagnostic carpal tunnel severity in the very elderly." Journal of Neurology, Neurosurgery & Psychiatry 89, no. 6 (2018): A32.2—A32. http://dx.doi.org/10.1136/jnnp-2018-anzan.78.

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IntroductionUltrasound measurement of median nerve cross-sectional area (CSA) at the wrist has emerged as an accurate and useful complement to electrophysiology in the diagnosis of carpal tunnel syndrome (CTS).AANEM, 2012 A number of studies have also shown a positive correlation between median nerve CSA and electrodiagnostic severity. After noting absence of the expected nerve enlargement on ultrasound in some very elderly patients, we sought to correlate nerve ultrasound and electrodiagnostic findings in a very elderly population and to compare this with a population of younger patients.Meth

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De Fretes, Elzina Dina, and Tri Juniarti. "Factor Determinant Implementation Vaccines for the Elderly." Science Midwifery 10, no. 4 (2022): 2503–9. http://dx.doi.org/10.35335/midwifery.v10i4.700.

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The elderly are vulnerable and at-risk groups exposed to the Covid 19 virus. However, the number of achievements immunization in the elderly is still relatively low compared to group age other. Various factors cause this thing. Destination study this to know the factors that influence implementation vaccine in advanced age. This research is an analytical research observation with an approach to a cross-sectional study. This research was carried out in the working area of Fakfak City Health Centre within six months for the elderly aged more than 60 years old as many as 30 selected respondents u

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Carneiro, Jair Almeida, Rafael Rodrigues Cardoso, Meiriellen Silva Durães, et al. "Frailty in the elderly: prevalence and associated factors." Revista Brasileira de Enfermagem 70, no. 4 (2017): 747–52. http://dx.doi.org/10.1590/0034-7167-2016-0633.

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ABSTRACT Objective: to know the prevalence and factors associated with frailty in elderly assisted by the Centro Mais Vida de Referência em Assistência à Saúde do Idoso (Mais Vida Health Reference Center for the Elderly) in the North of Minas Gerais, Brazil. Method: cross-sectional study, with sampling by convenience. Data collection occurred in 2015. Demographic and socioeconomic variables, morbidities, use of health services and the score of the Edmonton Frail Scale were analyzed. The adjusted prevalence ratios were obtained by multiple analysis of Poisson regression with robust variance. Re

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Chikhladze, Nana, Nino Tebidze, Tamar Chabukiani, et al. "The Attitudes, Needs, and Requirements at End of Life in the Republic of Georgia (Comparative Analysis of Groups of Patients With Cancer and Elders)." Journal of Palliative Care 33, no. 4 (2018): 252–59. http://dx.doi.org/10.1177/0825859718779455.

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Introduction: In developing a model of palliative care, the attitudes, needs, and requirements of its beneficiaries recognizing the limited remaining life expectancy need to be met. We aimed to map and compare these issues at the end of life in the groups of patients with advanced cancer and elderly individuals. Materials and Methods: The prospective study based on the analysis of semistructured interviews was conducted. Fifty individuals aged older than 85 and 50 incurable patients with advanced cancer were studied. Transcripts of interviews were analyzed qualitatively (the interviews were di

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Berretta, M., A. Bearz, S. Frustaci, et al. "FOLFOX2 in the Treatment of Advanced Colorectal Cancer: A Comparison Between Elderly and Middle Aged Patients." Journal of Chemotherapy 20, no. 4 (2008): 503–8. http://dx.doi.org/10.1179/joc.2008.20.4.503.

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Yoshimura, N., S. Kudoh, T. Kimura, S. Mitsuoka, and K. Hirata. "Phase II study of docetaxel and carboplatin in elderly patients with advanced non-small cell lung cancer." Journal of Clinical Oncology 24, no. 18_suppl (2006): 17013. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.17013.

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17013 Background: Single-agent chemotherapy has been considered as standard treatment for elderly patients with non-small cell lung cancer (NSCLC). However recent subset analyses suggest that platinum-based combination chemotherapy may be safely administered to the elderly with good performance status (PS). We evaluated the efficacy and safety of carboplatin and docetaxel in a phase II study of elderly patients aged 70 years or older. Methods: Chemotherapy-naive patients aged ≥70 years with advanced NSCLC (IIIB-IV), ECOG performance status (PS) of 0 or 1, a measurable lesion, and adequate orga

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Smitha, K1, B. T. Veena, Varadarajan Reethu, and Sushma. "A Comparative Study of Pregnancy Outcome in Elderly Primigravida and Younger Primigravida." International Journal of Current Pharmaceutical Review and Research 16, no. 01 (2024): 96–101. https://doi.org/10.5281/zenodo.10990816.

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AbstractBackground: Societal changes in maternal age demographics, marked by increased educational andprofessional pursuits, necessitate an in-depth examination of pregnancy outcomes for elderly primigravida.Understanding the complexities surrounding advanced maternal age is crucial for tailoring effective antenatalcare and interventions to ensure favorable maternal and neonatal outcomes.Objective: This study aims to compare pregnancy outcomes between elderly primigravida (≥35 years) andyounger primigravida.Methods: A 18-month comparative observational study at Kempegowda Institute of Medic

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Vatansever, Sinan, and Birsen Altay. "Being old during the COVID-19 pandemic in Turkey — a case study." Health Promotion & Physical Activity 25, no. 4 (2024): 31–36. http://dx.doi.org/10.55225/hppa.541.

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Pandemics affect millions of people and cause many deaths worldwide. Undoubtedly, the most affected vulnerable group in the epidemic has been the elderly. The elderly population is a very heterogeneous population with various combinations of geriatric syndromes, comorbidities, and disabilities. According to the WHO report, 89% of the mortality in the COVID-19 virus is seen in individuals aged 65 and over, called the elderly. For older people, the risk of transmission is higher due to the health conditions associated with aging. The weak immune system in the elderly and the advanced state of ch

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Pryce, I. G., R. D. Griffiths, R. M. Gentry, et al. "The Nature and Severity of Disabilities in Long-Stay Psychiatric In-patients in South Glamorgan." British Journal of Psychiatry 158, no. 6 (1991): 817–21. http://dx.doi.org/10.1192/bjp.158.6.817.

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Long-stay psychiatric in-patients in South Glamorgan were reviewed using the MRC Needs for Care assessment. The majority were middle aged or elderly and were severely disabled, with problems encompassing symptoms/behavioural difficulties, social skills, and physical health. In most, long-standing psychiatric illness was compounded by physical illness and cognitive deficits as age advanced, producing care needs that were greater than existing community services could meet.

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Lee, Dayong, Tae Hun Kim, and Taek Sang Lee. "Effectiveness of Obliterative Surgery in Managing Advanced Apical Prolapse in Elderly Women: A 20-Years of Single Surgeon’s Experience." Journal of Clinical Medicine 14, no. 9 (2025): 3101. https://doi.org/10.3390/jcm14093101.

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Objectives: The aim of this study was to evaluate the surgical outcomes, therapeutic efficacy, and psychological satisfaction of the Le Fort partial colpocleisis (LFC) procedure, an obliterative surgical treatment option, in elderly women with advanced apical prolapse, based on the 20-year surgical experience of a single surgeon. Methods: A retrospective cohort study was conducted on 81 women aged 60 and older who underwent LFC for advanced apical prolapse at a single institution from 2006 to 2025. Baseline characteristics, comorbidities, perioperative outcomes, complications, and patients’ sa

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Schild, Steven E., Philip J. Stella, Susan M. Geyer, et al. "The Outcome of Combined-Modality Therapy for Stage III Non–Small-Cell Lung Cancer in the Elderly." Journal of Clinical Oncology 21, no. 17 (2003): 3201–6. http://dx.doi.org/10.1200/jco.2003.12.019.

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Purpose: The North Central Cancer Treatment Group performed a phase III trial to determine whether chemotherapy plus either bid radiation therapy (RT) or daily (qd) RT resulted in a better outcome for patients with stage III non–small-cell lung cancer (NSCLC). No difference in survival was identified between the two arms. This secondary analysis was performed to examine the relationship between patient age and outcome. Patients and Methods: Two hundred forty-six patients were randomized to receive etoposide plus cisplatin and either RT qd or split-course RT bid. This retrospective study compar

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Bianchi, W., F. Maggiolo, and H. Ohnmeiss. "Ciprofloxacin in Elderly Patients with Underlying Chronic Diseases." Journal of International Medical Research 16, no. 5 (1988): 386–93. http://dx.doi.org/10.1177/030006058801600508.

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Age is not as important in predisposing to infections as are the associated problems peculiar to certain age groups. Factors such as the advanced age of the patients combined with the presence of chronic disease reduce their resistance to infection. This study comprises 212 elderly patients (aged 65–98 years) who were treated with 500–1000 mg/day ciprofloxacin for 1–18 days. Despite the high incidence of associated chronic diseases, microbiology showed that infections were eradicated in 88.5%. Clinical resolution occurred in 75.5% of patients and clinical failure occurred in 6.1%. Treatment wa

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Okawa, Yohei. "The Impact of Nutritional Therapy on Gastrointestinal Motility in Older Adults." Healthcare 11, no. 21 (2023): 2829. http://dx.doi.org/10.3390/healthcare11212829.

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Japan is becoming a superaged society, and nutrition therapy for the elderly population is very important. Elderly individuals often have multiple diseases and are prone to malnutrition. Furthermore, functional constipation, diarrhoea, faecal incontinence, etc., may occur despite no organic abnormality of digestive tract function. Due to these disabilities, the resulting malnutrition, and the slow recovery, it is often difficult for elderly individuals to reintegrate into society. Secondary or incorrect nutritional management increases complications, decreases physical function and worsens the

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Maciejczyk, Mateusz, Anna Zalewska, and Jerzy Robert Ładny. "Salivary Antioxidant Barrier, Redox Status, and Oxidative Damage to Proteins and Lipids in Healthy Children, Adults, and the Elderly." Oxidative Medicine and Cellular Longevity 2019 (December 5, 2019): 1–12. http://dx.doi.org/10.1155/2019/4393460.

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Despite the proven role of oxidative stress in numerous systemic diseases and in the process of aging, little is still known about the salivary redox balance of healthy children, adults, and the elderly. Our study was the first to assess the antioxidant barrier, redox status, and oxidative damage in nonstimulated (NWS) and stimulated (SWS) saliva as well as blood samples of healthy individuals at different ages. We divided 90 generally healthy people into three equally numbered groups based on age: 2–14 (children and adolescents), 25–45 (adults), and 65–85 (elderly people). Antioxidant enzymes

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Chou, Chao-Liang, Chun-Chieh Liu, Tzu-Wei Wu, et al. "Predictability of Cardiovascular Risk Scores for Carotid Atherosclerosis in Community-Dwelling Middle-Aged and Elderly Adults." Journal of Clinical Medicine 13, no. 9 (2024): 2563. http://dx.doi.org/10.3390/jcm13092563.

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The assessment of future risk of cardiovascular diseases (CVD) is strongly recommended for all asymptomatic adults without CVD history. Carotid atherosclerosis (CA) is a preclinical phenotype of CVDs. However, data on estimated future CVD risks with respect to preclinical atherosclerosis are limited. This community-based study aimed to assess the relationships between predicted CVD risks and CA. Methods: We enrolled 3908 subjects aged 40–74 years without CVD history and calculated their 10-year CVD risks using the Framingham Risk Score (FRS) and the Pooled Cohort Equations (PCE). Carotid plaqu

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