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1

Nwokoma, Ngozi Joy, Mark G. Swindells, Karoline Pahl, et al. "Pediatric Advanced Appendicitis." Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 19, no. 2 (2009): 110–13. http://dx.doi.org/10.1097/sle.0b013e31819ce3aa.

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2

Pogorelić, Zenon, Jakov Mihanović, Stipe Ninčević, Bruna Lukšić, Sara Elezović Baloević, and Ozren Polašek. "Validity of Appendicitis Inflammatory Response Score in Distinguishing Perforated from Non-Perforated Appendicitis in Children." Children 8, no. 4 (2021): 309. http://dx.doi.org/10.3390/children8040309.

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Background: This prospective observational study aimed to evaluate the validity of appendicitis inflammatory response (AIR) score in differentiating advanced (perforated) from simple (non-perforated) appendicitis in pediatric patients. Methods: A single-center prospective cross-sectional study was conducted between 1 January 2019 until 1 May 2020 including 184 pediatric patients who underwent appendectomy. Based on the intraoperative finding of advanced (n = 38) or simple (n = 146) appendicitis the patients were divided into two groups. Recipient-operator curve (ROC), with calculation of sensi
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3

Garfield, Jamie L., Robert H. Birkhahn, Theodore J. Gaeta, and William M. Briggs. "Diagnostic Pathways and Delays on Route to Operative Intervention in Acute Appendicitis." American Surgeon 70, no. 11 (2004): 1010–13. http://dx.doi.org/10.1177/000313480407001117.

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The purpose of this study was to determine the elements associated with delay in the evaluation of acute appendicitis at a community teaching hospital. We performed a retrospective chart review of patients undergoing operative exploration for presumed appendicitis in a 12-month period. Cases were categorized by the presence or absence of advanced radiographic imaging. Demographic information and time intervals from triage to operative incision were compared. One hundred twenty-four patients underwent operative exploration for presumed appendicitis. Forty-one patients had no advanced imaging, 6
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4

Lane, John S., Paul J. Schmit, Charles F. Chandler, Robert S. Bennion, and Jesse E. Thompson. "Ileocecectomy is Definitive Treatment for Advanced Appendicitis." American Surgeon 67, no. 12 (2001): 1117–22. http://dx.doi.org/10.1177/000313480106701201.

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Although appendectomy is the most commonly performed emergency operation septic complications of appendectomy remain a major source of morbidity. Historically, advanced appendicitis has been treated by appendectomy with cecostomy and/or drainage tubes. Our objective was to evaluate the use of ileocecal resection for the immediate treatment of advanced appendicitis. We examined the cases of all patients undergoing ileocecal resection for appendicitis from August 1989 through April 2000. There were 92 patients (60 male and 32 female) with a median age of 34 (range 6–71). Abdominal pain was prese
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5

Tavakoli, Amin, Paul Wadensweiler, Elizabeth Blumenthal, Eric Kuncir, Roozbeh Houshyar, and Taylor Brueseke. "Medical management of appendicitis in early-term pregnancy." BMJ Case Reports 13, no. 8 (2020): e234252. http://dx.doi.org/10.1136/bcr-2020-234252.

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A 19-year-old G1 at 37 weeks presented with acute non-ruptured appendicitis. Her advanced gestational age and surgical anatomy presented a complex surgical scenario. She was treated with intravenous antibiotics and induction of labour, which resulted in resolution of the appendicitis and an uncomplicated vaginal delivery at early term. This case is an example that appendicitis occurring in early-term pregnancy can be successfully managed with intravenous antibiotics, but this is a complex clinical scenario with a limited evidence base to make management decisions. Future studies of medical man
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6

ATASSI, KATHERINE A. "Appendicitis." Nursing 32, no. 8 (2002): 96. http://dx.doi.org/10.1097/00152193-200208000-00074.

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7

Santosh Mishra, Archan Ghimire, Rajesh Poudel, Sagun Thapa, Sanjay Shrestha та Pradip Chhetri. "Evaluation and Comparison of the Accuracy and Efficacy of Alvarado and Appendicitis Inflammatory Response Scoring in Acute Appendicitis". Journal of Universal College of Medical Sciences 11, № 01 (2023): 27–31. http://dx.doi.org/10.3126/jucms.v11i01.54622.

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INTRODUCTION
 Acute appendicitis (AA) is one of the most common causes of acute abdominal pain. Early surgery for acute appendicitis may lead to inadequate evaluation of differential diagnoses of acute abdominal pain and increases the chances of negative appendectomy, whereas delaying it leads to potential complications. Appendicitis inflammatory response (AIR) score, has been created to overcome shortcomings of the Alvarado score. In this, a mathematical model focused on detecting perforated appendicitis has been used. Unlike previously reported scores, this included C-reactive protein (C
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8

Lapsa, Sintija, Arturs Ozolins, Ilze Strumfa, and Janis Gardovskis. "Acute Appendicitis in the Elderly: A Literature Review on an Increasingly Frequent Surgical Problem." Geriatrics 6, no. 3 (2021): 93. http://dx.doi.org/10.3390/geriatrics6030093.

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With increased life expectancy and the growing total population of elderly patients, there has been rise in the number of cases of acute appendicitis in elderly people. Although acute appendicitis is not the most typical pathological condition in the elderly, it is not uncommon. Most of these patients require surgical treatment, and as with any acute surgical pathology in advanced age, treatment possibilities are affected by comorbidities, overall health status, and an increased risk of complications. In this literature review we discuss differences in acute appendicitis in the elderly populat
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9

Tehrani, Hassan Y., James G. Petros, R. Ravi Kumar, and Quyen Chu. "Markers of Severe Appendicitis." American Surgeon 65, no. 5 (1999): 453–55. http://dx.doi.org/10.1177/000313489906500515.

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Appendicitis is a common surgical disease that often presents with vague, inconclusive symptoms. Despite the development of technologically advanced diagnostic modalities, perforation has usually occurred before the surgeon sees the patient. Morbidity, length of stay, and hospital costs associated with appendiceal perforation have not changed markedly in the past 50 years. To evaluate prognostic markers for severe appendicitis, we reviewed 18 years’ worth of records of patients with appendicitis who were admitted to St. Elizabeth's Medical Center of Boston and found that the combination of his
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10

Tsang, TT. "The Strategy of a Shorter Course of Postoperative Intravenous Antibiotics for Advanced Appendicitis in Children." International Journal of General Medicine & Surger 2, no. 1 (2018): 1–5. https://doi.org/10.5281/zenodo.2639178.

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Objective: Antibiotic treatment is standard after appendectomy for advanced appendicitis in children with the aim to reduce postoperative complications. However, the evidence for deciding the duration of administration of the intravenous antibiotics (IVA) is limited. We present our experience focussing on the duration of IVA and the strategy for managing the complications. Methods: Retrospective review of patients undergoing an emergency appendectomy supervised by the senior surgeon (TT) over an 11-year period (2006-16) was done. Patient records were reviewed for operative findings, duration o
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11

Redfern, Vicky, and Gerri Mortimore. "Appendicitis: a clinical review." Gastrointestinal Nursing 20, no. 6 (2022): 22–29. http://dx.doi.org/10.12968/gasn.2022.20.6.22.

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Right iliac fossa pain is a daily encounter for advanced clinical practitioners (ACPs) working in the acute surgical setting, who are in an optimal position to provide holistic, quality patient-centred care for these individuals. The ACP role cannot be underestimated in this patient group; using the ACP's autonomous, adaptive capabilities and high level of critical thinking, they can improve patient experience and outcomes. This clinical review discusses the challenge of diagnosing appendicitis in people who present with right iliac fossa pain. In the first author's experience as a trainee ACP
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12

Ikonen, J., M. Juhola, M. Eskelinen, and E. Pesonen. "Parameters for a Knowledge Base for Acute Appendicitis." Methods of Information in Medicine 33, no. 02 (1994): 220–26. http://dx.doi.org/10.1055/s-0038-1635012.

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Abstract:Acute appendicitis is the most common cause of acute abdomen requiring surgical intervention. The clinical diagnosis of acute appendicitis is not always easy due to variable symptomatology, particularly at the onset. The contributions of history-taking and physical examination in the diagnosis of acute appendicitis was studied in connection with the Research Committee of the World Organization of Gastroenterology (OMGE) survey of acute abdominal pain. Especially the suitability of diagnostic parameters in the construction of an expert system for automatic decision making was studied.
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13

Pfadt, Ellen, and Dorothy S. Carlson. "Acute appendicitis." Nursing 39, no. 12 (2009): 72. http://dx.doi.org/10.1097/01.nurse.0000365033.56020.71.

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14

Kishe AS, Chilonga KS, Msuya D, et al. "A comparative study of Appendicitis inflammatory response (AIR) score with Alvarado score in diagnosis of acute appendicitis at KCMC Hospital." World Journal of Biology Pharmacy and Health Sciences 19, no. 2 (2024): 017–26. http://dx.doi.org/10.30574/wjbphs.2024.19.2.0479.

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Background: Acute appendicitis is an acute inflammation of the appendix, most resulted from obstruction of the lumen of the appendix. It is one of the most common causes of acute abdomen. Although a very common and long-known phenomenon, appendicitis remains a diagnostic challenge for most surgeons. Objective: To compare the validity of Appendicitis Inflammatory Response Score with Alvarado score in diagnosis of acute appendicitis at KCMC Hospital. Methods: A prospective hospital based cross sectional study done over a period of six months (September 2016 to March 2017). Patients were admitted
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15

Dr., Tapas Ghosh, Arpan Dey Dr., and Sudipto Konar Dr. "Spectrum of Clinical Presentations in Different Variants of Acute Appendicitis." International Journal of Research and Review 6, no. 5 (2019): 364–69. https://doi.org/10.5281/zenodo.3989507.

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Acute appendicitis is the commonest abdominal emergency. It is mainly a disease of teenagers and young adults affecting the most productive section of the population. So prolongation of morbidity due to negative laparotomy is unwanted and at the same time delay in diagnosis of acute appendicitis is apprehended. The present study was conducted on 75 histologically proved cases of acute appendicitis. Detailed clinical, morphological and histopathological features were studied. Abdominal pain was present in all patients and right iliac fossa was the usual site of abdominal pain. A significant num
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16

Kong, V., C. Aldous, J. Handley, and D. Clarke. "The cost effectiveness of early management of acute appendicitis underlies the importance of curative surgical services to a primary healthcare programme." Annals of The Royal College of Surgeons of England 95, no. 4 (2013): 280–84. http://dx.doi.org/10.1308/003588413x13511609958415.

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Introduction Appendicitis in the developing world is a cause of significant preventable morbidity. This prospective study from a regional hospital in South Africa constructs a robust cost model that demonstrates the cost effectiveness of an efficient curative surgical service in a primary healthcare-orientated system. Methods A prospective audit of all patients with acute appendicitis admitted to Edendale Hospital was undertaken from September 2010 to September 2011. A microcosting approach was used to construct a cost model based on the estimated cost of operative and perioperative interventi
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17

Sakai, S., K. Kobayashi, J. Nakamura, S. Toyabe, and K. Akazawa. "Accuracy in the Diagnostic Prediction of Acute Appendicitis Based on the Bayesian Network Model." Methods of Information in Medicine 46, no. 06 (2007): 723–26. http://dx.doi.org/10.3414/me9066.

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Summary Objectives : The diagnosis of acute appendicitis is difficult, and a diagnostic error will often lead to either a perforation or the removal of a normal appendix. In this study, we constructed a Bayesian network model for the diagnosis of acute appendicitis and compared the diagnostic accuracy with other diagnostic models, such as the naive Bayes model, an artificial neural network model, and a logistic regression model. Methods : The data from 169 patients, who suffered from acute abdominal pain and who were suspected of having an acute appendicitis, were analyzed in this study. Nine
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18

Santos, David, Yi-Ju Chiang, and Brian Badgwell. "Appendicitis in Cancer Patients is often Observed and Can Represent Appendiceal Malignancy." American Surgeon 82, no. 10 (2016): 1028–32. http://dx.doi.org/10.1177/000313481608201038.

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Appendectomy is standard of care for uncomplicated appendicitis, but cancer patients may not be optimal surgical candidates. Interval appendectomy is controversial, and appendiceal malignancy is rare. Study objectives were to review the role of surgery, observation, and interventional radiology (IR)-guided drainage in patients with appendicitis and advanced malignancy. Retrospective review was performed on cancer patients presenting to a tertiary academic cancer center from January 1, 2001 to December 31, 2014. Patients diagnosed with appendicitis were assigned to observation, surgery, and IR
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19

John, S. D. "The use of advanced imaging for appendicitis in children." Emergency Radiology 7, no. 6 (2000): 331–38. http://dx.doi.org/10.1007/pl00011853.

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20

Kishe, AS, KS Chilonga, D. Msuya, et al. "A comparative study of Appendicitis inflammatory response (AIR) score with Alvarado score in diagnosis of acute appendicitis at KCMC Hospital." World Journal of Biology Pharmacy and Health Sciences 19, no. 2 (2024): 017–26. https://doi.org/10.5281/zenodo.14991975.

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Background: Acute appendicitis is an acute inflammation of the appendix,&nbsp;most resulted from obstruction of the lumen of the appendix. It is one of the most common causes of acute abdomen. Although a very common and long-known phenomenon, appendicitis remains a diagnostic challenge for most surgeons. <strong>Objective:</strong>&nbsp;To compare the validity of Appendicitis Inflammatory Response Score with Alvarado score in diagnosis of acute appendicitis at KCMC Hospital. <strong>Methods:</strong>&nbsp;A prospective hospital based cross sectional study done over a period of six months (Sept
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21

Shekherdimian, Shant, and Daniel Deugarte. "Transumbilical Laparoscopic-Assisted Appendectomy: An Extracorporeal Single-Incision Alternative to Conventional Laparoscopic Techniques." American Surgeon 77, no. 5 (2011): 557–60. http://dx.doi.org/10.1177/000313481107700513.

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Recently the use of a single umbilical incision to perform an appendectomy has been described. The purpose of this study was to review our initial experience with transumbilical laparoscopic-assisted appendectomy (TULAA) in the pediatric population. A retrospective review of all pediatric patients treated for appendicitis over a 10-month period was performed. The surgical technique involved using a standard 3-mm or 5-mm trocar for visualization and insufflation. A dissecting/grasping instrument was used adjacent to the trocar through the same incision. Patient demographics, operative findings
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22

Ashutosh, Chavan. "Role of Early Surgical Intervention in the Acute Appendicitis: A Prospective Analysis." International Journal of Pharmaceutical and Clinical Research 16, no. 9 (2024): 494–97. https://doi.org/10.5281/zenodo.13904575.

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<strong>Background and Aim:&nbsp;</strong>Accurate diagnosis of acute appendicitis based on symptoms is essential in minimizing morbidity and mortality associated with perforation and other complications. This study aimed to explore the important factors that surgeons take into account when making decisions regarding suspected appendicitis cases.&nbsp;<strong>Material and Methods:&nbsp;</strong>The study included a total of one hundred patients, with a predominance of male participants. During the operation, the surgeon described the macroscopic appearance and assessed the severity of the appe
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23

Sousa-Rodrigues, Célio Fernando de, Amauri Clemente da Rocha, Amanda Karine Barros Rodrigues, Fabiano Timbó Barbosa, Fernando Wagner da Silva Ramos, and Sérgio Henrique Chagas Valões. "Correlation between the Alvarado Scale and the macroscopic aspect of the appendix in patients with appendicitis." Revista do Colégio Brasileiro de Cirurgiões 41, no. 5 (2014): 336–39. http://dx.doi.org/10.1590/0100-69912014005007.

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Objective: To evaluate the possible association between the scale of Alvarado (EA) and macroscopic appearance (MA) of the appendix in patients with acute appendicitis.Methods: after receiving the diagnosis of acute appendicitis, EA data were collected. During appendectomy, MA data were collected. Data from patients without appendicitis were excluded. The Spearman correlation test was used to compare EA with Appendix MA (p &lt; 0.05). Other variables were represented by simple frequency. The confidence interval (CI) of 95% was calculated for the correlation test.Results: Data were collected fro
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Abinasha, Mohapatra, Sahu Sunil, and Shekhar Mishra Himansu. "Retrospective Clinical Study of Acute Appendicitis in COVID-19 Pandemic: A Study of 100 Cases." International Journal of Pharmaceutical and Clinical Research 15, no. 8 (2023): 312–14. https://doi.org/10.5281/zenodo.11473947.

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<strong>Background:&nbsp;</strong>Acute appendicitis is having around 7% probability of occurrence over one&rsquo;s lifetime. Acute appendicitis is a common gastro-intestinal disease affecting 5.7&ndash;57 per 1lakh individual each year with the highest incidence in children and adolescents. Acute appendicitis is the most common reason for emergency abdominal surgery and must be distinguished from other causes of abdominal pain.&nbsp;<strong>Aim and Objective:</strong>&nbsp;To compare the clinical presentation, grade of presentation and post-operative complication of acute appendicitis before
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Kaplan, Carl, Raizada Vaid, and Michael Secko. "Identification of Pediatric Retrocecal Appendicitis Using Point of Care Ultrasound (POCUS)." POCUS Journal 10, no. 01 (2025): 192–95. https://doi.org/10.24908/pocusj.v10i01.17744.

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Acute appendicitis is the most common pediatric surgical emergency. Diagnosis may be made by targeted point of care ultrasound (POCUS) of the right lower quadrant (RLQ) abdomen. This can be performed by trained emergency physicians and has similar accuracy to ultrasound performed by radiology technologists and interpreted by radiologists (RADUS) [1,2]. Pediatric patients with appendicitis may present without classical clinical signs and symptoms. Retrocecal appendicitis is often diagnosed late at perforation due to the anatomical position limiting diagnosis with ultrasound, despite the high pr
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Bhatt, Somya, Rahul Saxena, Manish Pathak, et al. "Determining Surgeon’s Accuracy in Predicting the Severity of Appendicitis in Children: A Comparison Between Clinical Diagnosis and Intraoperative Findings." Journal of Indian Association of Pediatric Surgeons 30, no. 4 (2025): 469–76. https://doi.org/10.4103/jiaps.jiaps_248_24.

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ABSTRACT Background: Appendicitis is one of the most common surgical emergencies in children. Despite the availability of a plethora of advanced diagnostic imaging, diagnosis of acute appendicitis in young children remains a challenge. Materials and Methods: This prospective observational study compared the surgeon’s diagnosis with the intraoperative findings in the 78 children who underwent a laparoscopic appendectomy at a tertiary center over a duration of 18 months. After the clinical evaluation of the child, the surgeon was asked to fill out a pro forma. The delineation of complicated from
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Inamullah, Tejeswi S. Gutti, Mohammad Burhan Khan, Affan Asim, and Syed Muhammad Ali. "Appendicitis in the Geriatric Population: A Literature Review." International Journal of Innovative Research in Medical Science 9, no. 11 (2024): 690–94. http://dx.doi.org/10.23958/ijirms/vol09-i11/1997.

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Objective: This literature review examines the unique characteristics, challenges, and management strategies for appendicitis in the geriatric population, an age group often facing atypical symptom presentations and increased morbidity and mortality rates. Methods: A systematic review was conducted across multiple academic databases, including PubMed, Medline, and Google Scholar, to identify relevant articles on appendicitis in elderly patients, published upto June 2024. Keywords such as "appendicitis," "geriatric," "elderly," and "appendectomy" were used to retrieve studies examining the epid
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Maffezzoni, Deborah, Enrico Barbierato, and Alice Gatti. "Data-Driven Diagnostics for Pediatric Appendicitis: Machine Learning to Minimize Misdiagnoses and Unnecessary Surgeries." Future Internet 17, no. 4 (2025): 147. https://doi.org/10.3390/fi17040147.

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Pediatric appendicitis remains a challenging condition to diagnose accurately due to its varied clinical presentations and the non-specific nature of symptoms, particularly in younger patients. Traditional diagnostic approaches often result in delayed treatments or unnecessary surgical interventions, highlighting the need for more robust diagnostic tools. In this study, we explore the potential of machine learning (ML) algorithms to improve the diagnosis, management, and prediction of appendicitis severity in pediatric patients. Using a dataset of pediatric patients with suspected appendicitis
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Malik, Huma, Muhammad Amjad Chaudhry, Tooba Iqbal, Samra Riaz, Sunnia Abbasi, and Syed Khurrum Hussain Shah. "Role of Neutrophil-to-Lymphocyte Ratio as a Diagnostic Marker in Acute Appendicitis." Biological and Clinical Sciences Research Journal 6, no. 5 (2025): 209–12. https://doi.org/10.54112/bcsrj.v6i5.1745.

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Acute appendicitis is the most frequent abdominal surgical emergency worldwide. In Pakistan, where access to advanced imaging is limited in many healthcare settings, timely diagnosis remains challenging. The neutrophil-to-lymphocyte ratio (NLR) has emerged as a potential inflammatory biomarker to assist in the diagnosis of acute appendicitis. Objective: To evaluate the diagnostic accuracy of the neutrophil-to-lymphocyte ratio in predicting histopathologically confirmed acute appendicitis in patients presenting with clinical suspicion. Methods: A prospective observational study was conducted of
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Aritonang, Febria Valentine, Sanjaya Soebagio, and Yan Aditya. "Perbedaan jumlah leukosit darah antara pasien apendisitis akut dan apendisitis perforasi sebagai prediktor diagnosis di RSUD Pulang Pisau, Kalimantan Tengah, Indonesia." Intisari Sains Medis 13, no. 1 (2022): 289–92. http://dx.doi.org/10.15562/ism.v13i1.1297.

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Background. Not all health facilities in Indonesia have an advanced supporting examination to determine patients with acute appendicitis and perforated appendicitis. Several recent studies have shown there are differences in leukocyte count between patients with acute appendicitis and perforated appendicitis, which can be used as a predictor in diagnosing appendicitis and perforated appendicitis. Methods. This study used an observational analytic research method with a cross sectional approach to 40 patients. Data were taken from the appendicitis patients' medical records at Pulang Pisau Hospi
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Mooney, Janice, and Jonathan Hodgkinson. "Diagnosing acute appendicitis: a case study." British Journal of Nursing 33, no. 18 (2024): 876–83. http://dx.doi.org/10.12968/bjon.2023.0187.

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Advanced clinical practitioners (ACPs) are experienced health professionals educated to master's level. They are accountable for the assessment, diagnosis and treatment of individuals, and are responsible for making complex decisions. The case study presented in this article critically analyses the consultation involving a male patient in his sixties with a 2-day history of abdominal pain, who was referred by his GP to a surgical assessment unit. Analysis was carried out using the Calgary-Cambridge Model. The article discusses history-taking, abdominal examination and differential diagnoses, a
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Huang, Nana, Yishan Lu, Rui Wang, Ping Gao, and Ge Liu. "Clinical benefits of FOLFOXIRI combined with bevacizumab for advanced-stage primary signet ring cell carcinoma of the appendix: A case report." Medicine 102, no. 31 (2023): e34412. http://dx.doi.org/10.1097/md.0000000000034412.

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Rationale: Signet-ring cell carcinoma, which is an infrequent type of colorectal cancer. Abdominal pain is the primary presenting complaint of patients with acute appendicitis. It is difficult to diagnose patients with appendiceal carcinomas accompanying with symptoms of acute appendicitis. Patient Concerns: A 33-year-old female patient was admitted to our hospital, with chief complaints of “bilateral pelvic space-occupying lesions for 1 month, aggravated abdominal distension, and she accompanied with diarrhea for 3 days.” Diagnosis: The patient was with primary signet ring cell carcinoma of t
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33

Walker, Charles, Ali Moosavi, Katelyn Young, et al. "Factors Associated with Failure of Nonoperative Management for Complicated Appendicitis." American Surgeon 85, no. 8 (2019): 865–70. http://dx.doi.org/10.1177/000313481908500840.

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In recent years, nonoperative management of complicated appendicitis has become more common. Patients managed nonoperatively do well, but there is a paucity of literature on patients who fail nonoperative management. The purpose of this study was to examine the overall failure rate, morbidity associated with failure, and potential predictors of failure in nonop management of appendicitis. This is a descriptive retrospective review of patients from a single hospital system who were diagnosed with advanced appendicitis and underwent nonop management between January 1, 2007, and November of 2017.
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Procope, Beverly. "LAPAROSCOPIC VERSUS OPEN SURGERY FOR SUSPECTED APPENDICITIS." Gastroenterology Nursing 43, no. 2 (2020): 200–202. http://dx.doi.org/10.1097/sga.0000000000000508.

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35

Ali Khan, Amjad, Abdul Shaheed Asghar, Muhammad Ishaq, and Israr Ahmed Akhund. "APPENDICULAR DISEASES;." Professional Medical Journal 24, no. 08 (2017): 1114–19. http://dx.doi.org/10.29309/tpmj/2017.24.08.960.

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Acute appendicitis is a common cause of acute surgical abdomen and manyappendectomies are performed daily. All disease processes involving appendix will present asacute appendicitis. Clinically diagnosed acute appendicitis is treated by urgent appendectomy.As most of the removed appendices will reveal acute suppurative inflammation, therefore,appendectomy specimens are not usually submitted for histopathological examination unlessthe surgeon notices advanced disease or grossly recognizable abnormalities. Objectives: Thepurpose of this study is; 1, to explore the spectrum of diseases affecting
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36

Phan-Mai, Tuong-Anh, Truc Thanh Thai, Thanh Quoc Mai, Kiet Anh Vu, Cong Chi Mai, and Dung Anh Nguyen. "Validity of Machine Learning in Detecting Complicated Appendicitis in a Resource-Limited Setting: Findings from Vietnam." BioMed Research International 2023 (April 14, 2023): 1–8. http://dx.doi.org/10.1155/2023/5013812.

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Background. Complicated appendicitis, a potentially life-threatening condition, is common. However, the diagnosis of this condition is mainly based on physician’s experiences and advanced diagnostic equipment. This study built and validated machine learning models to facilitate the detection of complicated appendicitis. Methods. A retrospective cohort study was conducted based on medical charts of all patients undergoing a laparoscopic appendectomy at a city hospital during 2016-2020. The synthetic minority over-sampling technique (SMOTE) was used to adjust for the imbalance. Multiple classifi
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T, Kara, Karabulut YY, Bozdoğan AR, and Yüksek GE. "A Case of Collision Tumor of MALT Lymphoma and Poorly Differentiated Adenocarcinoma Diagnosed Incidentally After Appendectomy for a Clinical Presentation of Acute Appendicitis." Journal of Clinical Case reports and Images 1, no. 2 (2019): 1–7. http://dx.doi.org/10.14302/issn.2641-5518.jcci-18-2552.

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This report presents a case of collision tumors of low-grade B-cell lymphoma and poorly differentiated adenocarcinoma in the caceum of a 63-year-old woman. Lymphoma was diagnosed incidentally after appendectomy for a clinical presentation of acute appendicitis. Imaging follow-up demonstrated mesenteric lymphadenopathy and liver lesions, and all surgically resected regional mesenteric lymph nodes and liver biopsy were found to be infiltrated by both mucosa-associated lymphoid tissue (MALT) lymphoma and adenocarcinoma. Systemic chemotherapy was administered for advanced colonic adenocarcinoma wi
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38

Do‐Wyeld, Montgommery, Thomas P. Cundy, Stefan Court‐Kowalski, et al. "Improving quality and efficiency of care for advanced appendicitis in children." ANZ Journal of Surgery 91, no. 7-8 (2021): 1497–503. http://dx.doi.org/10.1111/ans.16929.

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39

Fallon, Sara C., Saif F. Hassan, Emily L. Larimer, et al. "Modification of an evidence-based protocol for advanced appendicitis in children." Journal of Surgical Research 185, no. 1 (2013): 273–77. http://dx.doi.org/10.1016/j.jss.2013.05.088.

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Bachur, Richard G., Kara Hennelly, Michael J. Callahan, and Michael C. Monuteaux. "Advanced Radiologic Imaging for Pediatric Appendicitis, 2005-2009: Trends and Outcomes." Journal of Pediatrics 160, no. 6 (2012): 1034–38. http://dx.doi.org/10.1016/j.jpeds.2011.11.037.

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Snelling, Carolyn M. H., Dan Poenaru, and John W. Drover. "Minimum postoperative antibiotic duration in advanced appendicitis in children: a review." Pediatric Surgery International 20, no. 11-12 (2004): 838–45. http://dx.doi.org/10.1007/s00383-004-1280-x.

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Schmittenbecher, Peter. "Minimum postoperative antibiotic duration in advanced appendicitis in children: a review." Journal of Pediatric Surgery 40, no. 7 (2005): 1216. http://dx.doi.org/10.1016/j.jpedsurg.2005.03.088.

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43

Pourmalek, Paria, X. Shao, P. Pourmalek, and N. Taheri. "Perforated Appendicitis in a Nursing Home Resident with Advanced Multiple Sclerosis." Journal of the American Medical Directors Association 19, no. 3 (2018): B7. http://dx.doi.org/10.1016/j.jamda.2017.12.030.

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Obinwa, Obinna, Nicola Motterlini, Michael Cassidy, Tom Fahey, and John Flynn. "Risk factors associated with advanced appendicitis and complications after childhood appendectomy." International Journal of Surgery 10, no. 8 (2012): S63. http://dx.doi.org/10.1016/j.ijsu.2012.06.334.

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45

Stockman, J. A. "Advanced Radiologic Imaging for Pediatric Appendicitis, 2005-2009: Trends and Outcomes." Yearbook of Pediatrics 2014 (2014): 171–73. https://doi.org/10.1016/j.yped.2012.08.007.

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46

Corrêa Neto, Isaac José Felippe, Amanda Gambi Robles, Victor Keniti Gomes Nishiyama, et al. "Retrospective Study of Patients Submitted to Appendectomy in a Tertiary Hospital: Is There a Difference between the Public and Supplementary Health System?" Journal of Coloproctology 44, no. 01 (2024): e27-e32. http://dx.doi.org/10.1055/s-0044-1779602.

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Abstract Introduction Appendicitis is the surgical disease with the highest prevalence in emergency rooms. Its clinical and/or surgical complications are associated with the time course of symptoms, age, comorbidities, and stages of the disease. Objectives To analyze the demographic and clinical data of patients who underwent appendectomy for acute appendicitis in a tertiary referral hospital in the city of São Paulo and compare these data between services provided by the Public and Supplementary Health System. Methodology Retrospective analysis of data from electronic medical records of patie
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Konjevod, Janja, Vanja Djukic, Tomislav Vukic, et al. "A Rare Case of Idiopathic Omental Necrosis in a Young Adult: Diagnostic Challenges and Management." Medical Archives 79, no. 3 (2025): 237. https://doi.org/10.5455/medarh.2025.79.237-240.

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Background: Idiopathic omental infarction (IOI) is a rare cause of acute abdominal pain that can clinically mimic more common conditions, such as acute appendicitis. IOI occurs due to vascular compromise of the greater omentum, leading to ischemia, pain, and often necrosis. Preoperative diagnosis remains challenging due to nonspecific clinical and laboratory findings, as well as the fact that clinicians rarely include IOI as a “usual suspect” in the differential diagnosis. Therefore, the condition is commonly identified intraoperatively. Objective: The aim of this article was to present a rare
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Alotaibi, Abdulrahman M., Leena H. Moshref, Rana H. Moshref, and Lina S. Felemban. "Analysis of 190 Female Patients after Appendectomy." Obstetrics and Gynecology International 2021 (November 27, 2021): 1–6. http://dx.doi.org/10.1155/2021/8036970.

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This study is a retrospective cohort review carried out at a single, private tertiary center. We included 190 female patients who underwent surgery for acute appendicitis between January 2016 and December 2018. Two groups of patients were analyzed based on the pregnancy. The main outcome measures were complication rate and risk of abortion during or after surgery. Out of 190 female patients, eight of them were pregnant (4.2%). The pregnant group more significantly underwent ultrasound investigation compared to the nonpregnant group. Complicated appendicitis present in two pregnant patients at
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O., Eboreime, and I. Asogun Z. "Tube Caecostomy: A Veritable Alternative in the Surgical Treatment of Advanced Appendicitis." British Journal of Medicine & Medical Research 21, no. 6 (2017): 1–5. https://doi.org/10.9734/BJMMR/2017/32682.

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<strong>Background:</strong> Advanced appendicitis poses a serious challenge to surgeons in poor resource settings and it is associated with a higher morbidity and mortality. <strong>Objective:</strong> To report the outcome of tube-caecostomy in the prevention of fistula formation after appendicectomy for appendicular mass, abscess or gangrenous appendix. <strong>Methods:</strong> A retrospective study involving all patients diagnosed with appendix mass, abscess and gangrenous appendix admitted into Central Hospital Benin City from October 2005 to October 2010. Data was collated from patient’
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Sooltan, Abdool Rahim, and Elina Sor. "Acute Appendicitis for a Patient with Situs Inversus." AIJR Synopsis 1, no. 1 (2025): 4–6. https://doi.org/10.21467/synopsis.1.1.2.

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Introduction: There was a considerable increase in scientific literature on acute appendicitis with situs inversus within the past few years in the field of surgical science. A comprehensive approach that includes advanced imaging techniques, like MRI and CT, may enhance diagnostic accuracy by providing a clearer depiction of anatomical variations [1]. The objective of this research was to analyse the perspectives of situs inversus implementation in acute appendicitis. Methodology: For this study, we reviewed 50 articles in English published in the time frame 2010-2024 from the PubMed, Google
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