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Dissertations / Theses on the topic 'Advanced oxidation protein products'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 March 2023

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1

DA, DALT L. "Caratterizzazione delle AOPP (Advanced Oxidation Protein Products) come indicatori di stress ossidativo e processi infiammatori nella bovina." Doctoral thesis, Università degli studi di Padova, 2011. http://hdl.handle.net/11577/3427417.

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The aim of this study was to characterize markers of oxidation of proteins in cattle, developing the assay method of AOPP (advanced oxidation protein products). Using standard commercial proteins (Bovine serum Albumin, bovine g-Globuline), oxidations In vitro were performed with chlorinated oxidant (hypochlorous acid) and hydroperoxide (cumene hydroperoxide) determining the relationship between AOPP and carbonyl groups by spectrophotometric and Western blotting analysis. The conformational changes of the standards were observed by one-dimensional electrophoresis kept in non-reducing condit

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Mamada, Sukamto Salang. "Studies on the Toxicity of Mixtures of Haloacetates and Ethanol in AML-12 Cells." University of Toledo Health Science Campus / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=mco1396531704.

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3

Bordignon, Milena. "Relationship between AOPP (Advanced Oxidation Protein Products) and bovine neutrophils "in vitro": AOPP production by neutrophils and AOPP effects on neutrophils ROS production and viability." Doctoral thesis, Università degli studi di Padova, 2013. http://hdl.handle.net/11577/3422657.

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The aim of the present study was to evaluate the relationship between AOPP (Advanced oxidation protein products) and bovine neutrophils 'in vitro'. For this purpose AOPP were produced "in vitro" by oxidizing bovine serum albumin with HOCl (hypochlorous acid) and bovine neutrophils were isolated from whole blood of dairy cattles. AOPP-BSA were incubated with freshly isolated bovine neutrophils, unstimulated and stimulated with PMA a strong activator of the respiratory burst. Neutrophils ROS production and viability were measured by luminol-amplified chemiluminescence and by MTT and lactate dehy

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4

Torbitz, Vanessa Dorneles. "AVALIAÇÃO DO FIBRINOGÊNIO COMO UMA NOVA FONTE PARA A FORMAÇÃO IN VITRO DE PRODUTOS PROTEICOS DE OXIDAÇÃO AVANÇADA." Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/6031.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Oxidative stress is characterized by an imbalance between the production of free radicals, particularly reactive oxygen species (ROS), and the defense capacity of the organism against these species, leading to a progressive oxidative damage. Proteins are considered to be the primary target for oxidative damage, since they are major components of biological systems and may neutralize 50 to 75% of free radicals. Recently, a new class of compounds formed as a result of oxidative stress was described, referred to as advanced oxidation

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Bochi, Guilherme Vargas. "FRUTOSE-1,6-BISFOSFATO E N-ACETILCISTEÍNA ATENUAM A FORMAÇÃO DE PRODUTOS PROTEICOS DE OXIDAÇÃO AVANÇADA, UMA NOVA CLASSE DE MEDIADORES INFLAMATÓRIOS, IN VITRO." Universidade Federal de Santa Maria, 2012. http://repositorio.ufsm.br/handle/1/8982.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The assessment of biomarkers of reactions involving reactive oxygen species have the potential not only to determine the extent of oxidative damage, but also to predict the effectiveness of therapeutic strategies aimed at reducing or preventing the damage promoted by oxidative stress. Recently, it has been described and characterized a new class of compounds formed in consequence of oxidative stress, designated as advanced oxidation protein products (AOPP). The accumulation of AOPP was first described in patients with chronic renal

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ASTORI, EMANUELA. "IN VITRO AND IN VIVO APPROACHES TO STUDY OXIDATIVE STRESS, ANEMIA AND DYSBIOSIS IN CHRONIC KIDNEY DISEASE." Doctoral thesis, Università degli Studi di Milano, 2021. http://hdl.handle.net/2434/818976.

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CKD is diagnosed when there’s a decreased kidney function shown by a GFR less than 60 ml / min (established for a reference man with 1.73 m² body surface area), or markers of kidney damage, or both, of at least 3 months duration. The severity of complications increases in parallel with the GFR decline. We focused on three comorbidities extremely common in CKD patients: oxidative stress and inflammation; anemia and dysbiosis. We investigated these CKD comorbidities both with in vitro and in vivo approaches. More in detail, regarding in vivo studies, we measured oxidative stress biomarkers in a

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7

Leitemperguer, Michele Rodrigues. "AVALIAÇÃO DOS NÍVEIS DE ALBUMINA MODIFICADA PELA ISQUEMIA, UM NOVO BIOMARCADOR DE ESTRESSE OXIDATIVO, EM PACIENTES COM ARTRITE REUMATOIDE." Universidade Federal de Santa Maria, 2013. http://repositorio.ufsm.br/handle/1/5990.

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Rheumatoid arthritis (RA) is a chronic inflammatory, autoimmune disease, characterized by peripheral and symmetrical polyarthritis that leads to joint destruction and deformity due to erosion of cartilage and bone. This is a common disease that affects approximately 1% of the world population and is more common in women than men, however, its peak incidence occurs between the fourth and sixth decades of life. Large amounts of reactive oxygen species (ROS) have been identified in the synovial fluid of RA patients, and such large amounts may lead to oxidative damage of hyaluronic acid, lipid, ca

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8

Danieli, Karina. "AVALIAÇÃO DO ESTRESSE OXIDATIVO ATRAVÉS DA DETERMINAÇÃO DE PRODUTOS DA OXIDAÇÃO AVANÇADA DE PROTEÍNAS (AOPP) EM PACIENTES COM ANEMIA MICROCÍTICA E HIPOCRÔMICA." Universidade Federal de Santa Maria, 2011. http://repositorio.ufsm.br/handle/1/5927.

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The etiology of anemia is characterized by abnormal hemoglobin synthesis. Iron deficiency is characterized by microcytic and hipochromic red cells and low serum ferritin, being the most prevalent nutritional deficiency worldwide, responsible for iron deficiency anemia (FA). Anemia of chronic disease (ACD) is considered a clinical syndrome associated with chronic inflammation, infectious disease, neoplastic or traumatic, being the second most frequent cause of anemia. The severity of anemia correlates with the degree of pathology. Both have functional iron deficiency. The objective of th

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9

Ostendorp, Thorsten. "Structure and function of the metal-binding protein S100B and its interaction with the receptor for advanced glycation end products." [S.l. : s.n.], 2006. http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-23752.

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10

Olvera, Vargas Hugo. "Study on the fate of pharmaceuticals in aqueous media : synthesis, characterization and detection of biotic and abiotic transformation products using electrochemical advanced oxidation processes and bioconversions." Thesis, Paris Est, 2014. http://www.theses.fr/2014PEST1179/document.

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La pollution des eaux superficielles et souterraines par des composés organiques est bien connue comme une préoccupation majeure de l'environnement dans de nombreux pays. Si les polluants prioritaires sont actuellement surveillés par la directive cadre européenne sur l'eau, il est désormais urgent de prendre en considération les nouveaux polluants dérivés de principes actifs des produits pharmaceutiques et d'identifier leurs produits de transformation à risque. Ce travail de thèse propose une étude globale sur l'état et l'avenir des produis pharmaceutiques dans l'environnement, sur l'exemple d

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11

Ren, Yimin. "Consequences of the interaction of amyloid beta with amyloid binding alcohol dehydrogenase and the receptor for advanced glycation end products." Thesis, St Andrews, 2008. http://hdl.handle.net/10023/503.

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12

Teles, Luana Duarte. "Avaliação da liberação de AGEs (Advanced Glycation End Products) e características sensorias em carne de frango e bovina em diferentes métodos de cocção." Universidade do Vale do Rio dos Sinos, 2014. http://www.repositorio.jesuita.org.br/handle/UNISINOS/4738.

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Submitted by Fabricia Fialho Reginato (fabriciar) on 2015-08-24T23:44:58Z No. of bitstreams: 1 LuanaTeles.pdf: 317432 bytes, checksum: 2fbd7369c410c0b3afac913a4136f4f0 (MD5)<br>Made available in DSpace on 2015-08-24T23:44:58Z (GMT). No. of bitstreams: 1 LuanaTeles.pdf: 317432 bytes, checksum: 2fbd7369c410c0b3afac913a4136f4f0 (MD5) Previous issue date: 2014-07-30<br>Nenhuma<br>As práticas alimentares têm sido objeto de estudo das Ciências da Saúde, principalmente, evidenciando a relação entre a dieta e algumas doenças crônicas. Dessa forma, é importante a identificação de formas alternati

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13

Sgroi, Massimiliano. "Formation and Control of N-Nitrosodimethylamine (NDMA) in Wastewater Reclaimed for Indirect Potable Reuse." Doctoral thesis, Università di Catania, 2014. http://hdl.handle.net/10761/1498.

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A large variety of disinfection by-products (DBPs) are formed during water treatment processes using chlorination. Disinfection with chloramines is often used to significantly reduce the formation of regulated DBPs. However, chloramination favours the formation of N-nitrosamines, which are emerging by-products of health concern. Of all the nitrosamines, N-nitrosodimethylamine (NDMA) has been most commonly detected in drinking water and wastewater. Nitrosamines can also be produced using different disinfectants, including chlorine dioxide and ozone. Wastewater often contains considerable concen

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14

Garzon, D. "HIGH RESOLUTION MASS SPECTROMETRIC STRATEGIES FOR DETECTION OF PROTEINS AND PEPTIDES COVALENTLY MODIFIED BY ELECTROPHILIC XENOBIOTICS AND ENDOGENOUS INTERMEDIATES." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/250677.

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Non enzymatic protein covalent modifications are involved in the toxic effects induced by electrophilic xenobiotics as well as by endogenous cytotoxic oxidation by-products. Aim of my Ph.D work was to set-up MS methods for the identification, characterization and quantification of non-enzymatic covalently modified proteins and peptides in biological matrices. To reach this goal both tandem MS and high resolution approaches were employed due to the wealth of structural and molecular information that these techniques can provide. As a first step the MS methods were applied for understanding in

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Guix, Ràfols Francesc Xavier. "Study of the pathophysiological role of nitric oxide on the amyloid-induced toxicity attending to the biochemical modifications and cellular damages." Doctoral thesis, Universitat Pompeu Fabra, 2009. http://hdl.handle.net/10803/7162.

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Aquesta tesi demostra que el peroxinitrit produït com a conseqüència del pèptid beta-amiloide (A) contribueix l'augment de la relació A42/A40 que ocorre a la malaltia d'Alzheimer. L'A42 contribueix a l'aparició de la malaltia degut a la seva major toxicitat (quan es compara amb l'A40) que resulta d'una gran estabilitat i capacitat agregativa. A més el peroxinitrit incrementa la toxicitat d'aquest degut a què potencia la seva agregació en forma d'oligomers altament tòxics. De fet els oligomers formats de nitro-A42 presenten una major toxicitat que

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16

Ferrando, Climent Laura. "Analysis of chemotherapy drugs and related compounds in aquatic environment: removal, transformation and risk evaluation in eco-friendly and advanced technologies." Doctoral thesis, Universitat de Girona, 2016. http://hdl.handle.net/10803/400719.

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In order to evaluate the increasing environmental and human risk of anticancer drugs in the environment, more information needs to be gathered about their presence, their toxicity, bioaccumulation and persistence. In addition, their removal performance in conventional wastewater treatment facilities and in alternative treatments needs further investigation efforts. The aim of this thesis is to fill knowledge gaps and provide tools for a better assessment about the presence and fate of anticancer drugs in the urban water cycle. The work presented hereby includes three main objectives: i) to dev

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17

Jelena, Molnar Jazić. "Efekti odabranih unapredenih procesa oksidacije i koagulacije na sadržaj prirodnih organskih materija u vodi." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2011. http://dx.doi.org/10.2298/NS20111010MOLNAR.

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Cilj ovog rada bio je da se u laboratorijskim uslovima ispitaju efekti odabranihunapredenih procesa oksidacije (Fenton proces, ozonizacija, TiO2-katalizovana ozonizacija,perokson proces i TiO2-katalizovan perokson proces) i koagulacije na sadržaj i strukturuprirodnih organskih materija u vodi, kao prekursora dezinfekcionih nusprodukata hlora.Karaterizacija POM frakcionisanjem pre i nakon navedenih oksidacionih tretmana ikoagulacije izvr&scaron;ena je u cilju ispitivanja mehanizama oksidacije i uklanjanja POM, kao iutvrdivanja promene reaktivnosti prekursorskog materijla DBP (trihalometana i ha

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18

Mirjana, Petronijević. "Uticaj oksidacionih procesa na bazi ozona, vodonik-peroksida i UV zračenja na sadržaj i reaktivnost prirodnih organskih materija u vodi." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2019. https://www.cris.uns.ac.rs/record.jsf?recordId=110672&source=NDLTD&language=en.

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Cilj  istraživanja  u  okviru  ove  doktorske  disertacije  je  utvrđivanje  efekata  različitihoksidacionih procesa na bazi ozona, vodonik-peroksida i UV zračenja na sadržaj i reaktivnost prirodnih  organskih  materija  (POM)  u  različitim  vodenim  matriksima.  Ispitivanja  su sprovedena  na  a)  podzemnoj  vodi  sa  teritorije  Kikinde  i  Temerina  (prirodni  matriks)  i  b) sintetičkom  vodenom  matriksu  (rastvoru&

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19

Wilde, Marcelo Luís. "Βeta-bloqueadores em efluente hospitalar: ocorrência, degradação por processos avançados de oxidação e identificação de subprodutos". Universidade Federal de Santa Maria, 2011. http://repositorio.ufsm.br/handle/1/4215.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>β-Blockers are an important group of prescription drugs; as a consequence of the large and continuous use, they are commonly found in the environment. This study assessed, preliminary, the inherent risk of the β-blockers Atenolol, Metoprolol and Propranolol, mostly used in the University Hospital of Santa Maria (HUSM), and showed that Propranolol has high Risk Quotient (RQ) of 0.56. HPLC-FLD and SPE methodologies were developed and optimized with the aid of experimental design in order to analyze the occurrence of β-blockers in t

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20

Fang, Wei-Kai, and 方暐凱. "Impacts of Advanced Oxidation Processes (AOPs) on Disinfection By-products Formation from Swimming Pools Water." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/zrj886.

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碩士<br>國立臺灣大學<br>環境衛生研究所<br>105<br>Chlorine-based disinfectants are widely used in swimming pools to maintain water quality and inhibit the spreads of waterborne diseases. During chlorination, natural organic matter (NOM) and swimmers-derived organic matter (such as perspiration and urine) will react with chlorine to generate disinfection by-products (DBPs) such as trihalomethanes (THMs), haloacetic acids (HAAs), haloacetonitriles (HANs) and which are harmful to human health. However, owing to the cost of maintenance and management, most of swimming pools use recirculation system and seldom rep

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Zakiyanov, Oskar. "Nové biomarkery u pacientů s onemocněním ledvin." Doctoral thesis, 2014. http://www.nusl.cz/ntk/nusl-338466.

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Chronic kidney disease (CKD) and acute kidney injury (AKI) are major public health problems. It is important to be able to identify those at high risk of adverse outcome, CKD progression and associated cardiovascular disease. The aim of the thesis was to study novel promising biomarkers, their relationship to kidney function, chronic inflammation and/or cardiovascular risk - placental growth factor (PlGF), pregnancy associated plasma protein A (PAPP-A), matrix metalloproteinase 2 (MMP-2), matrix metalloproteinase 9 (MMP-9), soluble receptor for advanced glycation end products (sRAGE), calcium

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22

Chen, Shie-chun, and 陳世宗. "Control and Formation of Chlorinated and Carbonyl Disinfection By-Products Using Advanced Oxidation Processes Combining with the Biological Fluidized-Bed Process." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/59436967415420829496.

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碩士<br>逢甲大學<br>環境工程與科學所<br>91<br>Abstract Chlorination is the most conventional process in drinking water treatment for a century. However, many types of halogenic disinfection by-products (DBPs), such as trihalomethanes (THMs) and haloacetic acids (HAAs), have been detected in the finished water and demonstrated to be carcinogenic and mutagenic chemicals having an negative impact on human health. Oxidation of organics in water by ozonation or advanced oxidation processes (AOPs) would be able to initiate the generation of great amount of carbonyl compounds and bromate ions, which have been fo

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23

Chin, Adeline S. "Evaluation of the removal of disinfection by-products precursors in Seymour water with ozone, UV and the advanced oxidation process ozone-UV." Thesis, 2003. http://hdl.handle.net/2429/15301.

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This research evaluated the treatment potential of ozone (O3), ultraviolet irradiation (UV) and the combined O3-UV advanced oxidation process (AOP) in the removal of two classes of disinfection byproduct (DBP) precursors (quantified as the trihalomethane formation potential (THMFP) and haloacetic acid formation potential( HAAFP)) from water samples obtained from the Seymour Reservoir near Vancouver, Canada. The water from this source, which provides 40% of the drinking water for the Greater Vancouver Regional District, is characterized by low pH (6.4) and low total organic carbon (1.3 —

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Lin, Yi-Pai, and 林依蓓. "Amyloid Precursor Protein (APP) Expression Is Regulated by Advanced Glycation End Products (AGEs) in SH-SY5Y Neuroblastoma Cell Line." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/51707117203570302128.

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碩士<br>長榮大學<br>醫學研究所<br>96<br>There are approximately 25 million Alzheimer’s disease (AD) patients in the world, and about 60％ of dementia patients were caused by AD in Taiwan. Senile plaques which are accumulated by amyloid beta (Aβ) and neurofibrillary tangles (NFTs) are the major hallmarks in the brain of AD patients. Some evidences have shown that inflammation and reactive oxygen species (ROS) increase in AD patients’ brain. But the pathogenesis of AD is unclear. Some risk factors of AD have been reported that include age, sex, genetics and chronic disease. The epidemiological studies have

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25

Thum, Wai-Yee, and 覃尉宜. "Involvement of p38 Mitogen-Activated Protein Kinase in Advanced Glycosylation End Products-Induced Cyclooxygenase-2 Expression in RAW 264.7 Macrophages." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/59460576888616367804.

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碩士<br>台北醫學院<br>生物醫學技術研究所<br>89<br>Advanced glycosylation end products (AGEs) have been implicated in the structural and functional alterations of proteins that occur during aging and long-term diabetes. In the present study, murine RAW 264.7 macrophages were incubated with poly-L-lysine (PLL)-AGEs to examine cyclooxygenase-2 (COX-2) protein expression. Treatment of RAW 264.7 cells with PLL-AGEs caused a dose-dependent increase in COX activity as reflected by PGE2 secretion (measured in the presence of exogenous arachidonic acid). Furthermore, treatment of RAW 264.7 cells with PLL-AGEs induc

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Nagarnaik, Pranav Mukund. "Source Characterization and Pretreatment Evaluation of Pharmaceuticals and Personal Care Products in Healthcare Facility Wastewater." Thesis, 2011. http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9316.

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Healthcare facility wastewaters are a potentially important and under characterized source of pharmaceuticals and personal care products to the environment. In this study the composition and magnitude of pharmaceuticals and personal care products (PPCPs) released into a single municipality’s wastewater system from a hospital, a nursing care facility, an assisted living facility and an independent living facility are presented for 54 pharmaceuticals, 8 hormones and 31 Alkylphenol ethoxylates (APEOs). Chemical oxidation using molecular ozone and advanced oxidation processes (AOPs) (UV-hydrogen

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Fernandes, Joana Cristina Taveira. "Water treatment with boron-doped diamond electrodes – A review on by-products formation." Master's thesis, 2021. http://hdl.handle.net/10362/118283.

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The formation and identification of by-products is crucial for understanding the possible environmental and public health risks of applying electrochemical advanced oxidation processes (EAOPs) in water treatment, involving boron-doped diamond (BDD) anodes. Despite the substantial research work concerning the use of BDD technology in water treatment review articles with a specific focus on by-products formation and their hazardous effects in the major environmental fields of application in water treatment are not available. This comprehensive review provides the current knowledge on

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Crosina, Quinn Kathleen. "A Bench-scale Evaluation of the Removal of Selected Pharmaceuticals and Personal Care Products by UV and UV/H₂O₂ in Drinking Water Treatment." Thesis, 2006. http://hdl.handle.net/10012/2632.

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A bench-scale study of the degradation of four selected pharmaceuticals and personal care products (PPCPs) was carried out using UV and UV/H₂O₂ treatment employing low pressure (LP) and medium pressure (MP) lamps. The target substances included the pharmaceutical compounds ibuprofen, naproxen, and gemfibrozil, along with the bactericide triclosan. There were four main objectives of the study, as follows: to evaluate the removal of the target compounds using UV irradiation alone and UV/H₂O₂, to determine the reaction kinetics for direct and indirect photolysis of each selected compound, to det

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McClintock, Carlee Suzanne Patterson. "Development of an Electrochemical Technique for Oxidative Surface Mapping to Investigate Solution-Phase Protein Dynamics with High Performance Mass Spectrometry and Advanced Informatics." 2010. http://trace.tennessee.edu/utk_graddiss/728.

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Oxidative protein surface mapping has gained popularity over recent years within the mass spectrometry (MS) community for gleaning information about the solvent accessibility of folded protein structures. The hydroxyl radical targets a wide breadth of reactive amino acids with a stable mass tag that withstands subsequent MS analysis. A variety of techniques exist for generating hydroxyl radicals, with most requiring sources of radiation or caustic oxidizing reagents. The purpose of this research was to evaluate the novel use of electrochemistry for accomplishing a comparable probe of protei

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Ostendorp, Thorsten Dag [Verfasser]. "Structure and function of the metal-binding protein S100B and its interaction with the receptor for advanced glycation end products / vorgelegt von Thorsten Dag Ostendorp." 2007. http://d-nb.info/983615985/34.

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Yang, Pei-Chen, та 楊珮禎. "Nuclear factor kappa B (NF-κB) proteasomal degradation by C-terminus of Hsc70-interacting protein (CHIP) protects cardiomyocytes from advanced glycation end- products (AGEs) - mediated apoptosis". Thesis, 2015. http://ndltd.ncl.edu.tw/handle/zkh6u9.

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Chang, Yu-Ling, and 張玉玲. "The Study of Food Intake Advanced Glycation End-products(AGEs) and Relationship of Serum of AGEs、C-Reactive Protein and HOMA-IR in the East Community on the TaichungCity." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/27244293518401394802.

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碩士<br>中國醫藥大學<br>營養學系碩士班<br>97<br>The formation and accumulation of advanced glycation end-products (AGEs) were believed to activate the complication of diabetes and being the risk factors of aging diseases. There were two aims in our study: (1) Estimate for common food AGEs intake in the east community on the Tiachung city and exploring the correlation between food AGEs intake and serum AGEs. (2) Study the effects of serum AGEs and insulin resistant、inflammation. We recruit 121 communities popular and collect the questionnaire of life-style and 24-hour diet record data and had the anthropometr

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