Academic literature on the topic 'Adverse reaction to medications'

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Journal articles on the topic "Adverse reaction to medications"

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Bibave, Kiran H. Tambe Ayush K.* Gangarde Atharv S. Vyavahare Sakshi S. Bandal Vaishnavi P. Dhas Sushma S. "Adverse Drug Reaction Reported To Injection Calcium Gluconate." International Journal in Pharmaceutical Sciences 2, no. 3 (2024): 828–36. https://doi.org/10.5281/zenodo.10853399.

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In the modern day, adverse drug reactions (ADR) are one of the most important subjects to evaluate. The World Health Organization (WHO) defines an adverse drug reaction (ADR) as any unpleasant and inadvertent reaction to a drug that happens at dosages used in humans for disease prophylaxis, diagnosis, or therapy; or for altering physiological function. This definition intentionally leaves out therapeutic failures, overdoses, drug abuse, noncompliance, and medication errors.  Furthermore, it has been considered a noteworthy adverse event that arises from a medical product-related intervent
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Eghbali-Zarch, Maryam, Reza Tavakkoli-Moghaddam, Fatemeh Esfahanian, Amir Azaron, and Mohammad Mehdi Sepehri. "A Markov decision process for modeling adverse drug reactions in medication treatment of type 2 diabetes." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 233, no. 8 (2019): 793–811. http://dx.doi.org/10.1177/0954411919853394.

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Type 2 diabetes has an increasing prevalence and high cost of treatment. The goal of type 2 diabetes treatment is to control patients’ blood glucose level by pharmacological interventions and to prevent adverse disease-related complications. Therefore, it is important to optimize the medication treatment plans for type 2 diabetes patients to enhance the quality of their lives and to decrease the economic burden of this chronic disease. Since the treatment of type 2 diabetes relies on medication, it is vital to consider adverse drug reactions. Adverse drug reaction is undesired harmful reaction
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Kandolf-Sekulović, Lidija, and Tatjana Radević. "Cutaneous Adverse Drug Reactions / Dematološka neželjena dejstva lekova." Serbian Journal of Dermatology and Venerology 4, no. 2 (2012): 61–76. http://dx.doi.org/10.2478/v10249-012-0005-8.

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Abstract Adverse drug reactions may be defined as undesirable clinical manifestations resulting from administration of a particular drug; this includes reactions due to overdose, predictable side effects, and unanticipated adverse manifestations. Adverse drug effects on the skin are among the most frequent reactions and, according to a study, account for approximately 14% of all adverse drug reactions. However, the incidence of cutaneous adverse effects in general population is unknown. Systemic drug administration results in various cutaneous adverse reactions, and medications used in the tre
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danjuma, mohammed, Bhagya Sree, Unwam Jumbo, et al. "Outcome of COVID-19 Positive Patients with type 2 Diabetes and Polypharmacy: an Examination of a Tertiary Hospital Cohort." Yemen Journal of Medicine 4, no. 1 (2025): 117–22. https://doi.org/10.63475/yjm.v4i1.0051.

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Background: COVID-19-positive patients are at increased risk of adverse clinical outcomes, with type 2 diabetes cohorts at substantially higher risk compared to the general population. The additional role of diabetic and non-diabetic polypharmacy in these patients' clinical course has remained unexamined. In this study we have comprehensively examined the role of polypharmacy in the determination of mortality outcomes in patients with COVID-19 clinical syndrome. Methods: We retrospectively examined case notes and electronic records of N = 497 patients with type 2 diabetes and COVID-19 infectio
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Speicher, Leigh, Sheena Crosby, and Michael J. Schuh. "Pharmacogenomics Testing Confirmation of Carbamazepine Induced DRESS Reaction of an HLA-A*31:01 Positive, Polypharmacy Patient." INNOVATIONS in pharmacy 12, no. 4 (2021): 20. http://dx.doi.org/10.24926/iip.v12i4.4341.

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Pharmacogenomics (PGx) melds well with polypharmacy as another tool to identify medication related problems (MRPs) more specifically so they may be solved most effectively. PGx can pre-emptively assist in medication selection, medication dosing or identify better medications for patients already taking a medication. PGx can also confirm suspect medications of causing MRPs such as adverse drug reactions (ADRs) or drug interactions. In this case, PGx testing confirmed presence of a serious human leukocyte antigen (HLA) drug reaction with eosinophilia and systemic symptoms (DRESS) after a suspect
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Yogita D. Pol, Yogita D. Pol, Omkar A. Devade Omkar A. Devade, Prathamesh Narale Prathamesh Narale, Sahil S. Gole Sahil S.Gole, and Dipali Sirsam Dipali Sirsam. "A Review on Adverse Drug Reaction." International Journal of Pharmaceutical Research and Applications 10, no. 3 (2025): 566–72. https://doi.org/10.35629/4494-1003566572.

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Adverse Drug Reactions (ADRs) are unintended and harmful responses to medications that occur at normal therapeutic doses. They represent a significant challenge in clinical practice, contributing to increased morbidity, prolonged hospital stays, and additional healthcare costs. ADRs can range from mild allergic reactions to severe, life-threatening conditions, and they are a leading cause of patient safety concerns worldwide. Effective detection, monitoring, and reporting systems—such as pharmacovigilance—are essential for minimizing risks associated with drug therapy. This abstract highlights
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Gomes, Daniel, Maria Teresa Herdeiro, Inês Ribeiro-Vaz, Pedro Lopes Ferreira, and Fátima Roque. "Adverse Drug Reactions and Potentially Inappropriate Medication in Older Patients: Analysis of the Portuguese Pharmacovigilance Database." Journal of Clinical Medicine 11, no. 8 (2022): 2229. http://dx.doi.org/10.3390/jcm11082229.

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Criteria have been developed to identify potentially inappropriate medications that can enhance adverse reactions, highly prevalent in older patient’s therapy. This study aimed to identify potentially inappropriate medications within the adverse drug reactions reported in the Portuguese pharmacovigilance system, characterizing the reports where inappropriate medications were identified. INFARMED, I.P. provided all adverse drug reactions reported from January to December 2019 in 65-year-old and older patients. Adverse drug reactions were characterized according to the System Organs Classes, ser
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Shrivastava, Pranjul, and Syed Sajid Ali Syed Sabir Ali. "Assessing the effectiveness of state-level pharmacy laws on opioid prescribing practices." Journal of Neonatal Surgery 14, no. 1S (2025): 323–28. https://doi.org/10.52783/jns.v14.1540.

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Despite their positive impacts on health, medications can have negative side effects because of adverse drug reactions (ADRs). Physicians, pharmacists, and nursing staff have a duty to use caution while prescribing medication. Patients are becoming more conscious of drug-related issues in today's consumer-driven world, and they want to be included in the decision-making process for many elements of their prescription and health care. This study concludes that polypharmacy, a history of bad drug responses, and coexisting illnesses are independent predictors of adverse drug reactions. Elderly pe
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Ashish, kumar* Abhishek Shrivastava Dr. Jitendra Banweer. "Adverse Drug Reaction Monitoring." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 1996–2001. https://doi.org/10.5281/zenodo.15389007.

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Adverse drug reactions (ADRs) are unintended and harmful effects of medications that pose a significant threat to patient safety. Monitoring and reporting these reactions is a critical component of pharmacovigilance, aiming to ensure safe and effective drug use. This article highlights the importance of ADR monitoring, outlines the systems and methods used globally and in India, and discusses the need for increased awareness and collaboration among healthcare professionals. Strengthening ADR monitoring can reduce drug-related risks, improve therapeutic outcomes, and enhance public health.
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Truong, Mimi, Wubshet Tesfaye, Kamal Sud, et al. "Drug-Related Problems and Sick Day Management Considerations for Medications that Contribute to the Risk of Acute Kidney Injury." Journal of Clinical Medicine 13, no. 2 (2024): 343. http://dx.doi.org/10.3390/jcm13020343.

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Background: Medication use during acute illness increases the risk of experiencing drug related problems (DRPs), including acute kidney injuries. It is recommended that potentially nephrotoxic medications are withheld during acute illness, including sulfonylureas, angiotensin converting enzyme inhibitors, diuretics, metformin, angiotensin receptor blockers, non-steroidal anti-inflammatories and sodium glucose co-transporter 2 inhibitors (SADMANS). It is unknown if Australian pharmacists currently provide sick day medication management advice regarding SADMANS medications. Hence, we aimed to id
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Dissertations / Theses on the topic "Adverse reaction to medications"

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Alves, Lilian Dias dos Santos. "Reações adversas à medicamentos associadas à prescrição de medicamentos potencialmente inapropriadas em idosos um estudo coorte /." Botucatu, 2019. http://hdl.handle.net/11449/181389.

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Orientador: Paulo José Fortes Villas Boas<br>Resumo: Introdução: A prescrição de Medicamentos Potencialmente Inapropriados (MPIs) é altamente prevalente em idosos e estes frequentemente estão associados à maior risco de interações medicamentosas, aumento das admissões hospitalares e Reações Adversas à Medicamentos (RAM), podendo ser prejudiciais à saúde do idoso. Objetivo: Analisar a prevalência de MPI em idosos em uma unidade de internação de hospital terciário e associação com a ocorrência de RAM durante a hospitalização. Material e Métodos: Trata-se de um estudo longitudinal, do tipo coorte
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McKnight, David. "Medication incidents in a private hospital : frequency, type, causes and outcomes." Thesis, Curtin University, 2011. http://hdl.handle.net/20.500.11937/1254.

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Background: Medication Safety has become a major health issue in Australia and internationally. Medication use is a part of most people lives with around seven in ten Australians and nine in ten older Australians having taken at least one medication over a two week period. But the taking of medications is not devoid of risk to the patient and a subsequent cost to society. This risk of an adverse outcome can be due to a predictable or idiosyncratic direct effect of the medication (adverse drug reaction) or a breakdown in the systems involved in the management of medications (medication incident
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Star, Kristina. "Safety of Medication in Paediatrics." Doctoral thesis, Uppsala universitet, Institutionen för folkhälso- och vårdvetenskap, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-197323.

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Background: In paediatrics, the limited documentation to guide medication, the lack of suitable dosage forms, and the continuous development in childhood present a scenario where safety of medication is a particular challenge. Aim: To explore reported adverse drug reactions (ADRs) and the challenges in prescribing and administering medicines in paediatrics, in order to identify and suggest areas needing international surveillance within medication safety and improvement in the clinical setting. Methods: Four exploratory studies were conducted. Worldwide reporting of suspected ADRs (individual
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Torelly, Ethel Maris Schroder. "Avaliação de efetividade, custos e eventos adversos de bombas de infusão de medicamentos : um ensaio clínico randomizado." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2009. http://hdl.handle.net/10183/24263.

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Objetivo: Este estudo objetivou avaliar a precisão de infusões de medicamentos em dois modelos de Bomba de Infusão (BI), de equipo específico do fabricante e de equipo universal, a concordância entre estes dois modelos e sua relação de custo e efetividade. Método: Foi realizado um ensaio clínico randomizado em pacientes internados em um hospital geral universitário de 740 leitos. As unidades de internação foram randomizadas através de sorteio simples para cada modelo de equipamento e os pacientes foram incluídos de acordo com indicação de uso de BI, conforme protocolo institucional. Os tipos d
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Ferret, Laurie. "Anticoagulants oraux, réutilisation de données hospitalières informatisées dans une démarche de soutien à la qualité des soins." Thesis, Lille 2, 2015. http://www.theses.fr/2015LIL2S016/document.

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Introduction :Les anticoagulants oraux soulèvent des problématiques majeures en termes de risque hémorragique et de bon usage. L’informatisation du dossier médical offre la possibilité d’accéder à de grandes bases de données que l’on peut exploiter de manière automatisée. L’objectif de ce travail est de montrer comment la réutilisation de données peut permettre d’étudier des problématiques liées aux anticoagulants et accompagner une démarche d’assurance de la qualité des soins. MéthodesCe travail a été réalisé sur les données informatisées (97 355 séjours) d’un centre hospitalier général. Pour
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Motter, Fabiane Raquel. "Desenvolvimento de critérios explícitos adaptados à realidade brasileira para avaliação do uso de medicamentos potencialmente inapropriados para idosos." Universidade do Vale do Rio dos Sinos, 2018. http://www.repositorio.jesuita.org.br/handle/UNISINOS/7150.

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Submitted by JOSIANE SANTOS DE OLIVEIRA (josianeso) on 2018-08-08T13:48:43Z No. of bitstreams: 1 Fabiane Raquel Motter_.pdf: 88399023 bytes, checksum: 3b609e9bf1fb7252cd2973a8db6869be (MD5)<br>Made available in DSpace on 2018-08-08T13:48:43Z (GMT). No. of bitstreams: 1 Fabiane Raquel Motter_.pdf: 88399023 bytes, checksum: 3b609e9bf1fb7252cd2973a8db6869be (MD5) Previous issue date: 2018-03-20<br>CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>UNISINOS - Universidade do Vale do Rio dos Sinos<br>O uso de Medicamentos Potencialmente Inapropriados (MPIs) em idosos pode
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Nita, Yunita. "Adverse drug reaction reporting in Australian hospitals." Thesis, Curtin University, 2002. http://hdl.handle.net/20.500.11937/1234.

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Adverse drug reactions (ADRs) are known to be a major cause of morbidity and mortality. However, only a small proportion are reported. An increase in the number and quality of reports by improving ADR reporting systems in hospitals, could improve patient outcomes and save healthcare costs. The first part of this project was to review the ADR reporting systems in Australian hospitals and to determine factors contributing to the ADR reporting rate. Data were collected by a postal, self-administered questionnaire. Questionnaires were sent to 299 chief pharmacists of Australian hospitals listed in
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Nita, Yunita. "Adverse drug reaction reporting in Australian hospitals." Curtin University of Technology, School of Pharmacy, 2002. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=14052.

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Adverse drug reactions (ADRs) are known to be a major cause of morbidity and mortality. However, only a small proportion are reported. An increase in the number and quality of reports by improving ADR reporting systems in hospitals, could improve patient outcomes and save healthcare costs. The first part of this project was to review the ADR reporting systems in Australian hospitals and to determine factors contributing to the ADR reporting rate. Data were collected by a postal, self-administered questionnaire. Questionnaires were sent to 299 chief pharmacists of Australian hospitals listed in
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Hennings, Steven. "Preventable Adverse Drug Events Avoided with the Implementation of “Smart” Infusion Technology." The University of Arizona, 2009. http://hdl.handle.net/10150/623911.

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Class of 2009 Abstract<br>OBJECTIVES: To compare possible differences in the proportion of serious potential ADEs associated with high-risk medications that were avoided by the use of AID technology in adult and pediatric ICU patients and to investigate the proportion of serious ADEs associated with high-risk medications as identified by root cause analyses (RCA) that occurred before and after AID implementation. METHODS: Study Site: This retrospective study was conducted at a tertiary care, academic medical center in Tucson Arizona. Design: This was a two-part retrospective study involving d
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Roberts, Pauline Isobel. "Adverse drug reaction monitoring and the community pharmacist." Thesis, University of Bradford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335542.

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Books on the topic "Adverse reaction to medications"

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Joseph, Dasta, and SpringerLink (Online service), eds. High-Risk IV Medications in Special Patient Populations. Springer-Verlag London Limited, 2011.

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U, Wintroub Bruce, ed. Adverse cutaneous reactions to medication. Williams & Wilkins, 1996.

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L, Tornatore Frank, ed. Reactions to psychotropic medication. Plenum Medical Book Co., 1987.

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Council for International Organizations of Medical Sciences. Working Group VIII. Practical aspects of signal detection in pharmacovigilance: Report of CIOMS Working Group VIII. CIOMS, 2010.

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Hoffmann, Richard P. Drug death: A danger of hospitalization : an expose of life-threatening adverse drug reactions and medication errors in hospitals. Thomas, 1989.

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1975-, Ernst Carrie L., and American Psychiatric Publishing, eds. Managing the side effects of psychotropic medications. American Psychiatric Pub., 2012.

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Inc, ebrary, ed. Patient safety informatics: Adverse drug events, human factors and IT tools for patient medication safety. IOS Press, 2011.

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Center for Drugs and Biologics (U.S.). Division of Drug and Biological Products Experience., ed. COSTART: Coding symbols for thesaurus of adverse reaction terms. 2nd ed. Department of Health and Human Services, Food and Drug Administration Center for Drugs and Biologics Division of Drug and Biological Products Experience, 1985.

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J, Waters William. Rhode Island Adverse Drug Reaction Reporting Project: Final report. RI Dept. of Health, Office of Health Policy, 1988.

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Center for Drug Evaluation and Research (U.S.). Office of Epidemiology and Biostatistics., ed. COSTART: Coding symbols for thesaurus of adverse reaction terms. 4th ed. National Technical Information Service, 1993.

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Book chapters on the topic "Adverse reaction to medications"

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Ferrari, Anna, and Peer Carsten Tfelt-Hansen. "Headache as an Adverse Reaction to Medication." In Handbook of Headache. Springer Milan, 2011. http://dx.doi.org/10.1007/978-88-470-1700-9_51.

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Zernig, Gerald, Sabine Bischinger, and Christoph Hiemke. "Adverse Drug Reactions, Intoxications and Interactions of Neuropsychotropic Medications." In NeuroPsychopharmacotherapy. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-56015-1_8-1.

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Zernig, Gerald, Sabine Bischinger, and Christoph Hiemke. "Adverse Drug Reactions, Intoxications and Interactions of Neuropsychotropic Medications." In NeuroPsychopharmacotherapy. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-62059-2_8.

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Dodiuk-Gad, Roni P., Wen-Hung Chung, and Neil H. Shear. "Adverse Medication Reactions." In Clinical and Basic Immunodermatology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-29785-9_25.

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Sequeira, Adrian, Andrew Abreo, and Kenneth Abreo. "Contrast and Medication Adverse Reactions." In Interventional Nephrology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-81155-6_29.

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Naylor, Robert. "The incidence of adverse events, adverse drug reactions (ADRs) and medication errors in hospitals." In Medication Errors. CRC Press, 2024. http://dx.doi.org/10.1201/9781315376394-2.

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Ferner, Robin E., and Sarah E. Mcdowell. "Fatal Medication Errors and Adverse Drug Reactions." In Mann's Pharmacovigilance. John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118820186.ch31.

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Scherrmann, Jean-Michel, Kim Wolff, Christine A. Franco, et al. "Adverse Reaction." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_4039.

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Naylor, Robert. "The incidence of adverse drug-induced events/reactions and medication errors in primary care." In Medication Errors. CRC Press, 2024. http://dx.doi.org/10.1201/9781315376394-3.

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Naylor, Robert. "The stages at which adverse drug-induced events/reactions and medication errors occur in hospitals." In Medication Errors. CRC Press, 2024. http://dx.doi.org/10.1201/9781315376394-4.

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Conference papers on the topic "Adverse reaction to medications"

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Chandra, Mohit, Siddharth Sriraman, Gaurav Verma, et al. "Lived Experience Not Found: LLMs Struggle to Align with Experts on Addressing Adverse Drug Reactions from Psychiatric Medication Use." In Proceedings of the 2025 Conference of the Nations of the Americas Chapter of the Association for Computational Linguistics: Human Language Technologies (Volume 1: Long Papers). Association for Computational Linguistics, 2025. https://doi.org/10.18653/v1/2025.naacl-long.553.

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Gope, Monika, and John Wang. "Using LLMs to Extract Adverse Drug Reaction (ADR) from Short Text." In 18th International Conference on Health Informatics. SCITEPRESS - Science and Technology Publications, 2025. https://doi.org/10.5220/0013160700003911.

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K, Prabhu, and Kanagasabapathy T. "Adverse Drug Reaction (ADR) Prediction using Integrated Machine Learning and Deep Learning Approaches." In 2024 4th International Conference on Soft Computing for Security Applications (ICSCSA). IEEE, 2024. https://doi.org/10.1109/icscsa64454.2024.00022.

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Li, Yufeng, Wenchao Zhao, Bo Dang, et al. "Research on Adverse Drug Reaction Prediction Model Combining Knowledge Graph Embedding and Deep Learning." In 2024 4th International Conference on Machine Learning and Intelligent Systems Engineering (MLISE). IEEE, 2024. http://dx.doi.org/10.1109/mlise62164.2024.10674360.

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Peng, Qiong, and Yafeng Ren. "A Hybrid Neural Network Model with Entity-related Knowledge for Adverse Drug Reaction Detection." In 2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2024. https://doi.org/10.1109/bibm62325.2024.10822078.

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Weng, Heng, Bo Xiao, Wei Zhou, and Yini Luo. "Real-World Drug-Adverse Reaction Prediction of Combined use of TCM Formula Granules and Western Medicine." In 2024 11th International Conference on Behavioural and Social Computing (BESC). IEEE, 2024. https://doi.org/10.1109/besc64747.2024.10780482.

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Rahman, Mohammad Mizanur. "Biodegradable SPC Polyurethane Coating." In CORROSION 2020. NACE International, 2020. https://doi.org/10.5006/c2020-14721.

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Abstract Self-polishing coatings (SPC) are widely being used in marine structures to protect metals from fouling. After restrictions on using toxic metals, coating industry are seeking environmentally-friendly SPC coatings that maintain their performance over extended periods. Unfortunately, most of the commercial SPC coatings contain different toxic materials, besides their performance is inadequate to prevent fouling under adverse conditions. The main mechanism of SPC coating is to facilitate the continuous renewal of the surface and the release of active compound via a hydrolysis reaction o
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Alakhali, Khaled, Ali Alshami, Abdullah Al-dahbali, Yaser Al-Worafi, Khairyani Khalid, and Faiz Mohammed. "The Role of the Clinical Pharmacist in A Case of Losartan-Induced Faintness and Dysarthria." In 5th International Conference on Biomedical and Health Sciences. Cihan University-Erbil, 2024. http://dx.doi.org/10.24086/biohs2024/paper.1343.

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Background: A common first-line antihypertensive the medication losartan has excellent absorption after being taken orally and undergoes extensive first-pass metabolic processes. Losartan commonly produces feelings of dizziness, headaches, lethargy, nausea, vomiting, impaired vision, and anaemia as side effects. Case summary: We discuss the case of a 59-year-old Yemeni lady who consumed losartan and had fainting and dysarthria. The patient was started on 50 mg daily oral losartan monotherapy for mild hypertension. After 12 days of utilizing the medication, she relocated to the emergency depart
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Rădulescu, Ionuţ Dragoș, Letiția Dobri Mirona, Codrina Moraru, Petronela Nechita, Ciprian Vlad, and Cezar Bichescu. "PHARMACOLOGICAL ADD-ON TREATMENTS IN MANAGING ANTIPSYCHOTIC-INDUCED WEIGHT GAIN." In The European Conference of Psychiatry and Mental Health "Galatia". Archiv Euromedica, 2023. http://dx.doi.org/10.35630/2022/12/psy.ro.24.

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Introduction: One of the most common antipsychotic (AP) related adverse drug reactions is weight gain, with a large proportion of patients started on AP even from the onset of schizophrenia, ending up gaining considerable weight. Aim: The study was designed to research current evidence for reducing weight gain through pharmacological supplementation or other practical interventions, in patients treated with APs. Method: A review of the published works found on MEDLINE and PubMed from 2015 to 2019 was done, concentrating mostly on research that specifically examined changes in body weight in in
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Floares, Doris, Diana Obistioiu, Anca Hulea, Ersilia Alexa, and Isidora Radulov. "THUJA OCCIDENTALIS AND PLATYCLADUS ORIENTALIS ANTIMICROBIAL ACTIVITY." In 23rd SGEM International Multidisciplinary Scientific GeoConference 2023. STEF92 Technology, 2023. http://dx.doi.org/10.5593/sgem2023v/6.2/s25.57.

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The rise of bacterial resistance to currently employed antibiotics is causing growing concerns for public health. The emergence of highly resistant bacterial strains results in the ineffectiveness of antibiotic treatments against many bacterial infections. As a result, there is an ongoing quest for new antimicrobial agents. This pursuit can take two main directions: one involves the design and synthesis of novel agents, while the other involves exploring natural sources to uncover previously undiscovered antimicrobial compounds. Herbal medications, particularly, have garnered renewed interest
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Reports on the topic "Adverse reaction to medications"

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Dong, Yi, LiJia Liu, Jianing Liu, Tianqi Liao, Jieru Zhou, and Huaien Bu. Incidences of Adverse Reactions in BNT162b2: A Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.1.0043.

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Review question / Objective: This study searched PubMed, Cochrane Library, Web of Science, Embase Electronics, and other databases to collect healthy adults aged 16 and older, subjects with no previous history of COVID-19 infection, A randomized controlled trial of Pfizer's vaccine BNT162b2 versus placebo. Using RevMan5.4 software, meta-analysis was conducted to compare the effects of injection of BNT162b2 and placebo on the incidence of adverse reactions in healthy adults over 16 years of age. Main indexes include total incidence of adverse reactions, the incidence of local adverse reactions
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Wu, Xin. The efficacy and safety of anti-CD20 antibody treatments in relapsing multiple sclerosis: a systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.6.0075.

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Review question / Objective: The objectives of this systematic review were to evaluate the efficacy and safety of the three existing anti-CD20 antibodies for the treatment of relapsing multiple sclerosis and to aid clinicians in choosing medications. Eligibility criteria: We set the inclusion criteria as follows: (1) study type: RCT; (2) language restriction: only available in English; (3) participants: patients ≥18 years of age diagnosed with relapsing MS, whether with a relapsing–remitting course or a secondary progressive course; (4) intervention: anti-CD20 antibody treatments including ocr
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Cooper, Dawn, Miranda Davies, Robert Platt, and Saad Shakir. Case-level causality assessment methodologies, their application, utility, and limitations in determining possible adverse drug reaction: A Scoping review protocol. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.1.0108.

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Treadwell, Jonathan R., Mingche Wu, and Amy Y. Tsou. Management of Infantile Epilepsies. Agency for Healthcare Research and Quality (AHRQ), 2022. http://dx.doi.org/10.23970/ahrqepccer252.

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Objectives. Uncontrolled seizures in children 1 to 36 months old have serious short-term health risks and may be associated with substantial developmental, behavioral, and psychological impairments. We evaluated the effectiveness, comparative effectiveness, and harms of pharmacologic, dietary, surgical, neuromodulation, and gene therapy treatments for infantile epilepsies. Data sources. We searched Embase®, MEDLINE®, PubMed®, the Cochrane Library, and gray literature for studies published from January 1, 1999, to August 19, 2021. Review methods. Using standard Evidence-based Practice Center me
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LI, Min, Ying SHEN, Liangzhen XIE, Fengjuan HAN, and Fangyuan LIU. Risk of adverse drug reaction of hematological system associated with poly (ADP-ribose) polymerase (PARP) inhibitors in the treatment of ovarian cancer: a meta-analysis of published trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.11.0140.

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Selph, Shelley S., Andrea C. Skelly, Tracy Dana, et al. Psychosocial and Pharmacologic Interventions for Disruptive Behavior in Children and Adolescents: A Systematic Review. Agency for Healthcare Research and Quality, 2025. https://doi.org/10.23970/ahrqepcsrdisruptive.

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Objectives. To determine the most effective treatments for clinically significant disruptive behaviors in children and adolescents. Data sources. Ovid® MEDLINE®, the Cochrane Library, PsycINFO®, and Embase® databases were searched from 2014 to July 22, 2024. Additionally, we reviewed all studies included in the prior 2015 Agency for Healthcare Research and Quality review. Review methods. We dual reviewed abstracts and full-text articles; data extraction was checked by a second reviewer; risk of bias and strength of evidence were assessed by two reviewers; and disagreements were resolved by con
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Ding, Yukang, Xixia Chen, and Yongpeng Ge. Inflammatory myopathy following coronavirus disease 2019 vaccination: a systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.9.0084.

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Review question / Objective: Reports of unexpected side effects have accompanied the vaccination of larger proportions of the population against coronavirus disease 2019 (COVID-19), including a few cases of inflammatory myopathy (IM). In a bid to improve understanding of the clinical course of vaccine complications, a systematic review of reported cases of IM following COVID-19 vaccination has been conducted. Condition being studied: Safety concerns have surrounded the vaccines since their development, with common adverse effects including local reaction at the site of injection and diverse no
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Lahav, Ori, Albert Heber, and David Broday. Elimination of emissions of ammonia and hydrogen sulfide from confined animal and feeding operations (CAFO) using an adsorption/liquid-redox process with biological regeneration. United States Department of Agriculture, 2008. http://dx.doi.org/10.32747/2008.7695589.bard.

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The project was originally aimed at investigating and developing new efficient methods for cost effective removal of ammonia (NH₃) and hydrogen sulfide (H₂S) from Concentrated Animal Feeding Operations (CAFO), in particular broiler and laying houses (NH₃) and hog houses (H₂S). In both cases, the principal idea was to design and operate a dedicated air collection system that would be used for the treatment of the gases, and that would work independently from the general ventilation system. The advantages envisaged: (1) if collected at a point close to the source of generation, pollutants would
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Introduction to MedDRA Labeling Grouping (MLG): a standardized approach to grouping adverse reactions in product safety labels. Council for International Organizations of Medical Sciences (CIOMS), 2024. http://dx.doi.org/10.56759/hmku5307.

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The Medical Dictionary for Regulatory Activities (MedDRA) is a terminology developed by the International Council for Harmonisation (ICH). While it is useful for precise coding of adverse events of medicines for data analysis, its high granularity can obscure the communication of adverse reactions in product labeling for healthcare practitioners. Many sponsors and regulators have therefore begun to develop their own approaches to clustering similar adverse reaction terms in medical product prescribing information on a product-by-product basis. However, there are no agreed-upon conventions that
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Severe Cutaneous Adverse Reactions. A consensus by a CIOMS Working Group. CIOMS, 2025. https://doi.org/10.56759/lrty1600.

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In clinical practice, there is mounting concern about the burden of SCAR in relation to novel biologics as well as the increasing cost of diagnosis and management. This consensus report provides unique insights and the latest thinking from renowned experts on this important topic. The skin is among the parts of the body most commonly affected by adverse drug reactions (ADRs). Cutaneous ADRs affect 2% to 3% of all hospitalized patients and have a wide spectrum of clinical manifestations, are caused by various medicinal products, and result from different pathophysiologic mechanisms. Hence, thei
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