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1

Alves, Lilian Dias dos Santos. "Reações adversas à medicamentos associadas à prescrição de medicamentos potencialmente inapropriadas em idosos um estudo coorte /." Botucatu, 2019. http://hdl.handle.net/11449/181389.

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Orientador: Paulo José Fortes Villas Boas<br>Resumo: Introdução: A prescrição de Medicamentos Potencialmente Inapropriados (MPIs) é altamente prevalente em idosos e estes frequentemente estão associados à maior risco de interações medicamentosas, aumento das admissões hospitalares e Reações Adversas à Medicamentos (RAM), podendo ser prejudiciais à saúde do idoso. Objetivo: Analisar a prevalência de MPI em idosos em uma unidade de internação de hospital terciário e associação com a ocorrência de RAM durante a hospitalização. Material e Métodos: Trata-se de um estudo longitudinal, do tipo coorte
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2

McKnight, David. "Medication incidents in a private hospital : frequency, type, causes and outcomes." Thesis, Curtin University, 2011. http://hdl.handle.net/20.500.11937/1254.

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Background: Medication Safety has become a major health issue in Australia and internationally. Medication use is a part of most people lives with around seven in ten Australians and nine in ten older Australians having taken at least one medication over a two week period. But the taking of medications is not devoid of risk to the patient and a subsequent cost to society. This risk of an adverse outcome can be due to a predictable or idiosyncratic direct effect of the medication (adverse drug reaction) or a breakdown in the systems involved in the management of medications (medication incident
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3

Star, Kristina. "Safety of Medication in Paediatrics." Doctoral thesis, Uppsala universitet, Institutionen för folkhälso- och vårdvetenskap, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-197323.

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Background: In paediatrics, the limited documentation to guide medication, the lack of suitable dosage forms, and the continuous development in childhood present a scenario where safety of medication is a particular challenge. Aim: To explore reported adverse drug reactions (ADRs) and the challenges in prescribing and administering medicines in paediatrics, in order to identify and suggest areas needing international surveillance within medication safety and improvement in the clinical setting. Methods: Four exploratory studies were conducted. Worldwide reporting of suspected ADRs (individual
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4

Torelly, Ethel Maris Schroder. "Avaliação de efetividade, custos e eventos adversos de bombas de infusão de medicamentos : um ensaio clínico randomizado." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2009. http://hdl.handle.net/10183/24263.

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Objetivo: Este estudo objetivou avaliar a precisão de infusões de medicamentos em dois modelos de Bomba de Infusão (BI), de equipo específico do fabricante e de equipo universal, a concordância entre estes dois modelos e sua relação de custo e efetividade. Método: Foi realizado um ensaio clínico randomizado em pacientes internados em um hospital geral universitário de 740 leitos. As unidades de internação foram randomizadas através de sorteio simples para cada modelo de equipamento e os pacientes foram incluídos de acordo com indicação de uso de BI, conforme protocolo institucional. Os tipos d
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5

Ferret, Laurie. "Anticoagulants oraux, réutilisation de données hospitalières informatisées dans une démarche de soutien à la qualité des soins." Thesis, Lille 2, 2015. http://www.theses.fr/2015LIL2S016/document.

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Introduction :Les anticoagulants oraux soulèvent des problématiques majeures en termes de risque hémorragique et de bon usage. L’informatisation du dossier médical offre la possibilité d’accéder à de grandes bases de données que l’on peut exploiter de manière automatisée. L’objectif de ce travail est de montrer comment la réutilisation de données peut permettre d’étudier des problématiques liées aux anticoagulants et accompagner une démarche d’assurance de la qualité des soins. MéthodesCe travail a été réalisé sur les données informatisées (97 355 séjours) d’un centre hospitalier général. Pour
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6

Motter, Fabiane Raquel. "Desenvolvimento de critérios explícitos adaptados à realidade brasileira para avaliação do uso de medicamentos potencialmente inapropriados para idosos." Universidade do Vale do Rio dos Sinos, 2018. http://www.repositorio.jesuita.org.br/handle/UNISINOS/7150.

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Submitted by JOSIANE SANTOS DE OLIVEIRA (josianeso) on 2018-08-08T13:48:43Z No. of bitstreams: 1 Fabiane Raquel Motter_.pdf: 88399023 bytes, checksum: 3b609e9bf1fb7252cd2973a8db6869be (MD5)<br>Made available in DSpace on 2018-08-08T13:48:43Z (GMT). No. of bitstreams: 1 Fabiane Raquel Motter_.pdf: 88399023 bytes, checksum: 3b609e9bf1fb7252cd2973a8db6869be (MD5) Previous issue date: 2018-03-20<br>CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>UNISINOS - Universidade do Vale do Rio dos Sinos<br>O uso de Medicamentos Potencialmente Inapropriados (MPIs) em idosos pode
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7

Nita, Yunita. "Adverse drug reaction reporting in Australian hospitals." Thesis, Curtin University, 2002. http://hdl.handle.net/20.500.11937/1234.

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Adverse drug reactions (ADRs) are known to be a major cause of morbidity and mortality. However, only a small proportion are reported. An increase in the number and quality of reports by improving ADR reporting systems in hospitals, could improve patient outcomes and save healthcare costs. The first part of this project was to review the ADR reporting systems in Australian hospitals and to determine factors contributing to the ADR reporting rate. Data were collected by a postal, self-administered questionnaire. Questionnaires were sent to 299 chief pharmacists of Australian hospitals listed in
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8

Nita, Yunita. "Adverse drug reaction reporting in Australian hospitals." Curtin University of Technology, School of Pharmacy, 2002. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=14052.

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Adverse drug reactions (ADRs) are known to be a major cause of morbidity and mortality. However, only a small proportion are reported. An increase in the number and quality of reports by improving ADR reporting systems in hospitals, could improve patient outcomes and save healthcare costs. The first part of this project was to review the ADR reporting systems in Australian hospitals and to determine factors contributing to the ADR reporting rate. Data were collected by a postal, self-administered questionnaire. Questionnaires were sent to 299 chief pharmacists of Australian hospitals listed in
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9

Hennings, Steven. "Preventable Adverse Drug Events Avoided with the Implementation of “Smart” Infusion Technology." The University of Arizona, 2009. http://hdl.handle.net/10150/623911.

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Class of 2009 Abstract<br>OBJECTIVES: To compare possible differences in the proportion of serious potential ADEs associated with high-risk medications that were avoided by the use of AID technology in adult and pediatric ICU patients and to investigate the proportion of serious ADEs associated with high-risk medications as identified by root cause analyses (RCA) that occurred before and after AID implementation. METHODS: Study Site: This retrospective study was conducted at a tertiary care, academic medical center in Tucson Arizona. Design: This was a two-part retrospective study involving d
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10

Roberts, Pauline Isobel. "Adverse drug reaction monitoring and the community pharmacist." Thesis, University of Bradford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335542.

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11

Kondo, Naoya. "Prescription of potentially inappropriate medications to elderly hemodialysis patients: prevalence and predictors." Kyoto University, 2015. http://hdl.handle.net/2433/195962.

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12

Bracken, Louise. "Avoiding adverse drug reactions in children : development of the Liverpool Adverse Drug Reaction Avoidability Assessment Tool." Thesis, University of Liverpool, 2015. http://livrepository.liverpool.ac.uk/2038179/.

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Adverse drug reactions (ADRs) are common in children. They contribute significantly to patient morbidity, mortality and hospitalisation costs. There is limited data on the avoidability of ADRs in children and wide variation in avoidability rates has been reported. There is currently no standardised method for determining avoidability and many of the established tools are not suitable or designed for use in paediatrics. The aim of this thesis was to develop and test a new avoidability assessment tool that is suitable for use in paediatrics. The stimulus for this work was difficulty using other
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13

Litell, Munjanja Yvonne. "Medication Reconciliation in the Elderly." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/6236.

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Medication therapy is the most prevalent and critical intervention of health delivery and the source of most errors in healthcare. Medication errors and associated adverse drug events (ADE) have serious health and economic ramifications, and in elderly patients ADE are the leading cause of morbidity and mortality. Medication reconciliation is the process of evaluating current medication treatment to manage the risk and optimize the outcomes of medication treatment by detecting, solving, and preventing ADEs. This education project answered the question whether education provided to long term ca
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14

Pham, Minh H. "Signal Detection of Adverse Drug Reaction using the Adverse Event Reporting System: Literature Review and Novel Methods." Scholar Commons, 2018. http://scholarcommons.usf.edu/etd/7218.

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One of the objectives of the U.S. Food and Drug Administration is to protect the public health through post-marketing drug safety surveillance, also known as Pharmacovigilance. An inexpensive and efficient method to inspect post-marketing drug safety is to use data mining algorithms on electronic health records to discover associations between drugs and adverse events. The purpose of this study is two-fold. First, we review the methods and algorithms proposed in the literature for identifying association drug interactions to an adverse event and discuss their advantages and drawbacks. Second,
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15

Norén, G. Niklas. "Statistical methods for knowledge discovery in adverse drug reaction surveillance." Doctoral thesis, Stockholm University, Department of Mathematics, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-6764.

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<p>Collections of individual case safety reports are the main resource for early discovery of unknown adverse reactions to drugs once they have been introduced to the general public. The data sets involved are complex and based on voluntary submission of reports, but contain pieces of very important information. The aim of this thesis is to propose computationally feasible statistical methods for large-scale knowledge discovery in these data sets. The main contributions are a duplicate detection method that can reliably identify pairs of unexpectedly similar reports and a new measure for highl
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Norén, G. Niklas. "Statistical methods for knowledge discovery in adverse drug reaction surveillance /." Stockholm : Department of Mathematics, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-6764.

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17

Green, Christopher Francis. "Hospital pharmacists and their role in adverse drug reaction reporting." Thesis, Liverpool John Moores University, 2000. http://researchonline.ljmu.ac.uk/5124/.

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18

Hildebrand, Bengt E. "Neurobiological basis of the nicotine withdrawal reaction : an experimental analysis /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-3874-1/.

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19

Almalki, Ziyad S. "Prevalence, Predictors, and Economic Impact of Drug-Drug Interaction Associated with Antipsychotic Medications among Adults in United States." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1491563282412964.

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20

Iessa, N. "Detecting suicide as an adverse drug reaction : association between suicide and montelukast." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1416397/.

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The hypothesised association between leukotriene receptor antagonists (LTRA) and suicide is not clear. In this thesis, causality assessments of Individual Case Safety Reports (ICSRs) and a novel pharmaco-vigilance method using electronic healthcare records (EHRs) are used to examine the strength of this hypothesis. This thesis is also the first to describe the application of the self-controlled case series (SCCS) methodology to the study of suicide and LTRA using UK primary care data. There are 5 components: 1) an initial screening of VigiBase, a global database of ICSRs for drugs associated w
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21

Cox, Anthony R. "An examination of adverse drug reaction reporting to the yellow card scheme." Thesis, Aston University, 2007. http://publications.aston.ac.uk/11068/.

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Chief pharmacists in 209 hospitals were surveyed about ADR reporting schemes, the priority given to ADR reporting, and attitudes towards ADR reporting. ADR reporting had a low managerial priority. Local reporting schemes were found to be operating in 37% trusts, but there were few plans to start new schemes. Few problems were discovered by the introduction of pharmacist ADR reporting. Chief pharmacists had concerns about the competence of hospital pharmacists to detect ADRs and were in favour of increased training. Lack of time on wards, and recruitment difficulties were suggested as reasons f
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22

Bäckström, Martin. "Spontaneous reporting of adverse drug reactions : possibilities and limitations /." Umeå : Farmakologi och klinisk neurovetenskap, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-525.

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23

Tang, Huaxiu. "Detecting Adverse Drug Reactions in Electronic Health Records by using the Food and Drug Administration’s Adverse Event Reporting System." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1470753258.

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24

Dahlberg, Gunnar. "Implementation and evaluation of a text extraction tool for adverse drug reaction information." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-134063.

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Inom ramen för Världshälsoorganisationens (WHO:s) internationella biverkningsprogram rapporterar sjukvårdspersonal och patienter misstänkta läkemedelsbiverkningar i form av spontana biverkningsrapporter som via nationella myndigheter skickas till Uppsala Monitoring Centre (UMC). Hos UMC lagras rapporterna i VigiBase, WHO:s biverkningsdatabas. Rapporterna i VigiBase analyseras med hjälp av statistiska metoder för att hitta potentiella samband mellan läkemedel och biverkningar. Funna samband utvärderas i flera steg där ett tidigt steg i utvärderingen är att studera den medicinska litteraturen fö
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25

Bezerra, Milena Pontes Portela. "Study of adverse events in an accredited secondary hospital of CearÃ: an approach to risk management." Universidade Federal do CearÃ, 2011. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7401.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>Study of adverse events in an accredited secondary hospital of CearÃ: an approach to risk management. Author: Milena Pontes Portela Beserra. Supervisor: ProfÂ. Dr Marta Maria de FranÃa Fonteles. [Master degreeâs dissertation. Post Graduation in Pharmaceutical Science. Department of Pharmacy â Federal University of CearÃ]. BACKGROUND: Hospital Risk Management acts in the prevention, detection, control or eliminate risks that could cause harm to patients, in Brazil this concept was implemented in 2001 by the National Agency for Sani
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Murphy, Kate. "Clozapine, concomitant medications and consumers: Assessing the accuracy of medication records and the lived experience of people prescribed clozapine under shared care arrangements." Thesis, Griffith University, 2018. http://hdl.handle.net/10072/381000.

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Schizophrenia is a serious long-term mental illness associated with significant morbidity and mortality. Clozapine is the most effective antipsychotic medication for the treatment of schizophrenia, however, due to potentially life-threatening haematological adverse effects, its use is restricted to people who have not responded to an adequate trial of at least two other antipsychotic medications. The high risk of adverse effects, associated mandatory monitoring and prescribing restrictions all mean that clozapine consumers often continue to be managed in a secondary care public mental health (
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Sousa, Mariana de Oliveira Brizeno de. "Intensive Monitoring of Adverse Reaction Related to Oxacillin in Patients Hospitalized in Fortaleza - CearÃ." Universidade Federal do CearÃ, 2004. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=320.

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FundaÃÃo de Amparo à Pesquisa do Estado do CearÃ<br>The large use of oxacillin in Brazilian hospitals and the ausence of scientific data confirming its safety, justify the necessity of carrying out well âstructured studies, identifying the existence of possible triggering factors of the reactions. AIM: To study the use of oxacillin and the occurrence of adverse reactions in two different groups, identifying risk factors associated. METHODS: Children using oxacillin were monitorized from October 2000 to July 2001 in the Universitary Hospital Walter CantÃdio (HUWC), as well as ones under treatme
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Al, dweik Rania. "Spontaneous Adverse Drug Reaction Reporting by Health Consumers in Canada: A Multi-Methods Study." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34942.

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Monitoring adverse drug reactions (ADRs) through pharmacovigilance is vital to health consumer safety. Health Canada accepts ADR reports from physicians, health consumers, lawyers and manufacturer. This study uses a multi-methods approach to evaluate health consumers ADR reporting to pharmacovigilance programs. Methods: Guided by Risk Perception Theory, this study involved three phases. 1) A systematic review to identify factors influencing health consumer ADR reporting 2) An observational study to compare health consumer and physician ADR reports received by Health Canada from 2000-2014
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Dubrall, Diana Ivonne [Verfasser]. "Analyses of Spontaneous Adverse Drug Reaction Databases Using Descriptive and Inferential Statistics / Diana Dubrall." Bonn : Universitäts- und Landesbibliothek Bonn, 2020. http://d-nb.info/1221669001/34.

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Choe, David, Matthew Stevens, Christina Summy, and Richard Herrier. "Optimizing Patient Adverse Drug Reaction History Through the Use of Structured Open Ended Questions." The University of Arizona, 2014. http://hdl.handle.net/10150/614206.

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Class of 2014 Abstract<br>Specific Aims: To assess if the use of three targeted open ended questions elicited more adverse drug reactions (ADRs) and allergies than found in the electronic medical record. Subjects: Inpatients at the University of Arizona Medical Center (UAMC) in Tucson, AZ that were 18 years or older and agreed to participate in the study. Methods: Data was collected usi
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Dubrall, Diana [Verfasser]. "Analyses of Spontaneous Adverse Drug Reaction Databases Using Descriptive and Inferential Statistics / Diana Dubrall." Bonn : Universitäts- und Landesbibliothek Bonn, 2020. http://d-nb.info/1221669001/34.

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32

Mayne, Rensche. "Community pharmacists’ knowledge, attitude and practices on adverse drug reaction reporting in South Africa." University of the Western Cape, 2018. http://hdl.handle.net/11394/6697.

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>Magister Scientiae - MSc<br>Pharmacovigilance involves the management of sub-standard drugs, medication errors, ―off-licence‖ drugs, abuse and misuse, lack of efficacy, poisoning, adverse drug reactions (ADRs), drug interactions, expired stock destruction and drug-related mortality. Regulators and the pharmaceutical industry rely on healthcare professionals, including pharmacists, to report ADRs. The majority of pharmacists work in retail community pharmacies and they are often the first point of contact when ADRs are experienced, since self-medication, misuse of over-the-counter (OTC)
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Gomes, Adriana Parente. "IncidÃncia de ReaÃÃes Adeversas a Medicamentos em Hospital de Ensino no Nordeste do Brasil." Universidade Federal do CearÃ, 2004. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=8453.

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FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico<br>INTRODUÃÃO: ReaÃÃes adversas a medicamentos - RAM constituem causa de morbi-mortalidade em pacientes hospitalizados, pÃem em risco a vida do paciente e representam aumento no tempo de internaÃÃo e nos custos hospitalares. OBJETIVOS: Determinar a incidÃncia de reaÃÃes adversas a medicamentos no Hospital UniversitÃrio Walter CantÃdio - HUWC, investigar quais os fatores que podem estar associados a esses eventos e propÃr medidas de prevenÃÃo ou reduÃÃo do impacto negativo dessas reaÃÃes. MÃTODOS: Estudo observacional, analÃ
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Roux, Leanne. "Pharmacovigilance: the responsibility of pharmaceutical companies to protect patients from drug-related harms." Thesis, University of the Western Cape, 2014. http://hdl.handle.net/11394/4234.

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>Magister Scientiae - MSc<br>Healthcare professionals (HCPs) have a primary role to play in the detection, assessment and spontaneous reporting of adverse drug reactions (ADRs). An improvement of their related knowledge, attitude and practice concerning pharmacovigilance and ADR reporting is vital. The objective of the study was to determine whether or not pharmacovigilance training, provided by a Pharmaceutical Company, would improve HCP’s perceptions and adherence to pharmacovigilance and ADR reporting. A quasi-experimental research design was used. A total of 44 HCPs participated in the stu
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Jolivot, Pierre-Alain. "Latrogénie médicamenteuse et admissions en réanimation : investigation des principales causes." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066463/document.

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Les événements indésirables médicamenteux (EIM) regroupent à la fois les effets indésirables des médicaments (ADR : Adverse Drug Reactions), considérés comme non évitables et les erreurs médicamenteuses (EM), considérées comme évitables. L’objectif de cette thèse est d’étudier les EIM conduisant à une admission en réanimation.Dans un premier temps, nous avons effectué une revue systématique de la littérature portant sur l’incidence des hospitalisations en réanimation pour EIM. Au total, 11 études ont été intégrées. L’incidence des EIM nécessitant une admission en réanimation variait de 0,37 à
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Monaco, Dominick, Jose Romero, and Jesus Solis. "A Comprehensive Literature Review of Non-­‐cough Adverse Drug Reactions (ADRs) Associated With Angiotensin." The University of Arizona, 2010. http://hdl.handle.net/10150/623789.

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Class of 2010 Abstract<br>OBJECTIVES: To comprehensively review medical literature and report angiotension converting enzyme inhibitors (ACE-­‐I) adverse drug reactions including, incidences, mechanism of action, predisposing conditions, and report prevention and treatments. METHODS: This was a descriptive retrospective study of data related to ACE-­‐I adverse drug reactions other than ACE-­‐I induced cough. It was to review the ADR that accompany with the use of ACE-­‐I. Literature obtained through search engines MEDLINE and OVID SP available through the Arizona Health and Science Library at
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O'Brien, Michelle University of Ballarat. "A study of multiple perspectives and knowledge in adverse drug reaction decision-making : Volume 1." University of Ballarat, 2004. http://archimedes.ballarat.edu.au:8080/vital/access/HandleResolver/1959.17/12769.

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Injury and illness associated with drugs are major problems in Australia and around the world, despite significant developments in the area of adverse drug reaction (ADR) decision support technology. The aims of this thesis are: to investigate the ADR decision domain; to determine factors that may assist in the prevention, detection and management of ADRs; and, to inform the pre-requirements analysis phase of the development of decision support systems. An approach has been taken that permits open and grounded study of the decision environment. This approach can then be used to frame and infor
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O'Brien, Michelle. "A study of multiple perspectives and knowledge in adverse drug reaction decision-making : Volume 1." Thesis, University of Ballarat, 2004. http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/36308.

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Injury and illness associated with drugs are major problems in Australia and around the world, despite significant developments in the area of adverse drug reaction (ADR) decision support technology. The aims of this thesis are: to investigate the ADR decision domain; to determine factors that may assist in the prevention, detection and management of ADRs; and, to inform the pre-requirements analysis phase of the development of decision support systems. An approach has been taken that permits open and grounded study of the decision environment. This approach can then be used to frame and infor
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O'Brien, Michelle. "A study of multiple perspectives and knowledge in adverse drug reaction decision-making : Volume 1." University of Ballarat, 2004. http://archimedes.ballarat.edu.au:8080/vital/access/HandleResolver/1959.17/14606.

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Injury and illness associated with drugs are major problems in Australia and around the world, despite significant developments in the area of adverse drug reaction (ADR) decision support technology. The aims of this thesis are: to investigate the ADR decision domain; to determine factors that may assist in the prevention, detection and management of ADRs; and, to inform the pre-requirements analysis phase of the development of decision support systems. An approach has been taken that permits open and grounded study of the decision environment. This approach can then be used to frame and infor
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40

Moses, Geraldine Michelle. "Increasing the frequency, quality and breadth of adverse drug reaction reporting by consumers and health professionals /." [St. Lucia, Qld.], 2005. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18939.pdf.

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41

Segomotso, Nametso Patience. "Knowledge, attittudes and practices of healthcare professionals towards adverse drug reaction reporting in Mafikeng Provincial Hospital." Thesis, University of Limpopo ( Medunsa Campus), 2011. http://hdl.handle.net/10386/424.

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Thesis (MPH)--University of Limpopo, 2011.<br>Abstract Background: Prevention, monitoring and reporting of adverse drug reactions is still a challenge among healthcare professionals. Even though some adverse drug reactions are minor and can be resolved quickly some can cause permanent disability or death. A recent South African study in a secondary hospital found that 6.3% of medical admissions were due to adverse drug reactions, which is similar to proportions found in developed countries. It is the responsibility of the healthcare professionals to detect, investigate, manage and report adve
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Al-Alhazmi, Naif N. N. "Role of pharmacists in adverse drug reaction reporting in Holy City of Makkah, Saudi Arabia : characterisation of models for evaluating pharmacovigilance in the Holy City of Makkah and attitude and awareness of pharmacists towards Adverse Drug Reaction Reporting." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/6254.

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Health care systems in Saudi Arabia and elsewhere play a significant role in the lives of individuals as well as society at large. Although healthcare aims at enhancing the quality of life it can sometimes happen that treatment itself can lead to a diminution of the quality of life due to unexpected adverse effects. These problems may cause therapeutic failures or even drug-related morbidity and mortality. Consequently there is a need to have in place a system, conventionally known as Pharmacovigilance. The aims of Pharmacovigilance are to identify, quantify and continuously monitor all drug u
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Guzzo, Giovanni Carvalho. "Profile of adverse events in bioequivalence trials at the Clinical Pharmacology Unit since 2000 to 2003." Universidade Federal do CearÃ, 2004. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=146.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>The inexistence of medicines that act only in one target cell leads to a possible interaction at others cell structures which are not related to their therapeutic action, coming to the appearance of adverse drug reactions (ADR). The Pharmacovigillance System may lead to a better ADR analysis at a health or research institution, making itself essential for adverse events (AE) registering throughout clinical trials and more efficient investigation and notification afterwards. With the objective of evaluation of AE registered duri
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Pinheiro, Luis Correia. "Vigilância activa de eventos após vacinação." Master's thesis, Faculdade de Ciências Médicas. Universidade Nova de Lisboa, 2008. http://hdl.handle.net/10362/4843.

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A vigilância de efeitos indesejáveis após a vacinação é complexa. Existem vários actores de confundimento que podem dar origem a associações espúrias, meramente temporais mas que podem provocar uma percepção do risco alterada e uma consequente desconfiança generalizada acerca do uso das vacinas. Com efeito as vacinas são medicamentos complexos com características únicas cuja vigilância necessita de abordagens metodológicas desenvolvidas para esse propósito. Do exposto se entende que, desde o desenvolvimento da farmacovigilância se tem procurado desenvolver novas metodologias que sejam conco
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Osho, Folasade Monisola. "Knowledge, attitudes and practices of adverse drug reaction reporting among nurses in a tertiary hospital in South West Nigeria." University of the Western Cape, 2018. http://hdl.handle.net/11394/6906.

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Magister Public Health - MPH<br>Background: Healthcare providers are critical to collecting information on drug safety and successful adverse drug reaction (ADR) reporting. The roles of doctors and pharmacists have been recognized as important to voluntary ADR reporting and their roles are consistently being investigated. However, despite the strategic role of nurses in medicine administration, their role in ADR reporting has not been widely explored, particularly in sub-Saharan African countries. Aim: To assess the knowledge, attitudes and practice of ADR reporting amongst nurses in Lagos
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Figueiredo, PatrÃcia Mandali de. "UtilizaÃÃo da flutamida em indicaÃÃes nÃo aprovadas pela ANVISA: aspectos referentes à seguranÃa, efetividade, avaliaÃÃo do risco e estratÃgias para contornÃ-lo." Universidade Federal do CearÃ, 2004. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7987.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>nÃo hÃ<br>A Flutamida à um medicamento anti-androgÃnico nÃo esterÃide aprovado para o tratamento do cÃncer de prÃstata. Seu efeito hepatotÃxico foi conhecido desde o inÃcio do perÃodo de comercializaÃÃo, hà mais de 10 anos. Em marÃo e junho de 2002, a Unidade de FarmacovigilÃncia da ANVISA recebeu as primeiras comunicaÃÃes de Ãbitos por hepatite fulminante associados ao uso da substÃncia (medicamento manipulado) em jovens do sexo feminino. A literatura mundial nunca registrara caso semelhante. O objetivo deste trabalho foi revisa
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Gouws, Stephanus Andries. "The impact of hospital surveillance programmes on the incidence of adverse drug reaction reporting in a South African teaching hospital." Master's thesis, University of Cape Town, 1989. http://hdl.handle.net/11427/27186.

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Post-marketing surveillance refers to any non-experimental or observational study, method, or monitoring strategy that is applied to obtain information on drug experience (primarily adverse) after a drug has been approved for clinical use. One of the major problems in post-marketing surveillance studies is the lack or under-reporting of drug experiences by health care professionals. This study was developed to describe the impact of three different prescription event monitoring programmes on the reporting of adverse drug reactions (ADR's) in the hospital situation. The intensive ADR monitoring
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Bui, Thu-Tam T. "A pharmaceutical risk management model." Oklahoma City : [s.n.], 2006.

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Zhang, Yi. "Application of Hyper-geometric Hypothesis-based Quantication and Markov Blanket Feature Selection Methods to Generate Signals for Adverse Drug Reaction Detection." University of Cincinnati / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1353343669.

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Thörnqvist, Maud. "Sjuksköterskans uppföljning av läkemedel i kommunens äldreomsorg : en empirisk studie med kvantitativ ansats." Thesis, Högskolan Dalarna, Omvårdnad, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:du-4209.

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Bakgrund: Det är en vanlig arbetsuppgift för sjuksköterskan att följa upp effekt och eventuella biverkningar av läkemedelsbehandling för återkoppling till ordinerande läkare. I och med att sjuksköterskan i den kommunala äldrevården har en konsultativ roll, är informationen mellan henne och vårdpersonalen, som är nära patienten dygnet om, mycket viktig. Denna del av läkemedelskedjan är av central betydelse för att minska onödigt lidande för den äldre patienten i form av läkemedelsrelaterade problem. Syfte: Att kartlägga hur sjuksköterskan i kommunens äldreomsorg följer upp läkemedelsordinatione
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