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1

Hollister, J., and Suzanne Bowyer. "Adverse Side Effects of Corticosteroids." Seminars in Respiratory and Critical Care Medicine 8, no. 04 (1987): 400–405. http://dx.doi.org/10.1055/s-2007-1012680.

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2

Mary, AN Seles Xavier, Das Mazumder Mithila, and Pavan Kumar S. "A Mixed Cohort Study on Adverse Events Following Pentavalent Vaccine and Its Perception among Parents." International Journal of Current Pharmaceutical Review and Research 15, no. 12 (2023): 470–74. https://doi.org/10.5281/zenodo.11520808.

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Background and Objective: Vaccination stands as one of the most effective strategies for disease preventionand place and pivotal role in family and public health. Vaccines significantly reduce morbidity and mortalityamong children. However, despite its benefits vaccination can occasionally result in some adverse effects.Furthermore, while the vast majority of children experience no adverse effects to a vaccine, a small percentagemay exhibit mild to severe side effects such as fever, redness and soreness of the injection site to convulsion andencephalopathy. Being informed about these potential
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3

MacKrill, Kate, Greg D. Gamble, Debbie J. Bean, Tim Cundy, and Keith J. Petrie. "Evidence of a Media-Induced Nocebo Response Following a Nationwide Antidepressant Drug Switch." Clinical Psychology in Europe 1, no. (1) (2019): e29642. https://doi.org/10.32872/cpe.v1i1.29642.

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<b>Background</b>: In 2017, patients on a generic or branded antidepressant venlafaxine were switched to a new generic formulation (Enlafax). In February and April 2018, two major NZ media outlets ran stories about the new generic being less effective and causing specific side effects. This study aimed to examine the effect of the media coverage on drug side effects reported to the national Centre for Adverse Reactions Monitoring (CARM) and whether the specific symptoms reported in the media increased compared to side effects not reported in the media. <b>Method</b>: We analysed monthly advers
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4

FLAKER, GREG C., and DOUGLAS CHAPMAN. "Adverse Side Effects Associated with Mexiletine." Clinical Progress in Electrophysiology and Pacing 4, no. 6 (1986): 602–7. http://dx.doi.org/10.1111/j.1540-8167.1986.tb01740.x.

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5

Huang, Liang-Chin, Xiaogang Wu, and Jake Y. Chen. "Predicting adverse side effects of drugs." BMC Genomics 12, Suppl 5 (2011): S11. http://dx.doi.org/10.1186/1471-2164-12-s5-s11.

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6

Rowe, Jonathan A., Matthew G. Hattenhauer, and David C. Herman. "Adverse Side Effects Associated With Latanoprost." American Journal of Ophthalmology 124, no. 5 (1997): 683–85. http://dx.doi.org/10.1016/s0002-9394(14)70907-9.

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7

Robertson, Deborah. "Side effects and adverse drug reactions." Nurse Prescribing 15, no. 10 (2017): 512–14. http://dx.doi.org/10.12968/npre.2017.15.10.512.

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8

Pichler, W. J. "Adverse side-effects to biological agents." Allergy 61, no. 8 (2006): 912–20. http://dx.doi.org/10.1111/j.1398-9995.2006.01058.x.

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9

Beaumont, G., S. Kasper, J. O'Hanlon, and J. Mendlewicz. "Antidepressant side effects and adverse reactions." Depression 2, no. 3 (1994): 138–44. http://dx.doi.org/10.1002/depr.3050020305.

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10

Hsu, Hsiu-Ling. "Side Effects of COVID-19 Vaccinations." Clinical Pathology & Research Journal 8, no. 1 (2024): 1–3. http://dx.doi.org/10.23880/cprj-16000183.

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In December 2020, the first COVID-19 vaccinations were granted emergency use permission in the US.1.2 billion vaccination doses have been delivered worldwide. However, some individuals are hesitant to get the COVID-19 vaccine due to safety concerns and unwanted effects. In randomized clinical trials of COVID-19 vaccinations, side effects reported included injection site discomfort, redness, swelling, as well as systemic symptoms such as weariness, headache, muscle or joint pain. Serious adverse events were infrequent. Although the majority of side effects were moderate, research found that 50%
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11

M.C. Besag, Frank. "Editorial (Adverse Effects, Adverse Events and Side-Effects: Does the Terminology Matter?" Current Drug Safety 6, no. 1 (2011): 1–2. http://dx.doi.org/10.2174/157488611794479964.

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12

Kotra, Vijay Kumar. "A Study on Adverse Effects of Antiepileptic Drugs in a Tertiary Care Hospital." International Journal of Toxicological and Pharmacological Research 13, no. 11 (2023): 121–23. https://doi.org/10.5281/zenodo.10998489.

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<strong>Background:</strong>&nbsp;A study was planned to overlook the adverse effects of antiepileptic drugs in tertiary care hospital&nbsp;<strong>Methods:</strong>&nbsp;It is a cross sectional study conducted on total of 184 patients in the medical department of tertiary care hospital. The data was entered in Microsoft excel. Inclusion criteria includes patients who are diagnosed with epilepsy and are aged greater than 17 years.&nbsp;<strong>Results:</strong>&nbsp;Among 184 patients 56.5% were male and 43.4% were female. About 43% were treated with monotherapy and &nbsp;And 57% were treated
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13

SATISH, S. VILAS PAI* RAMAKRISHNA SHABARAYA A. "A Study To Identify The Prevelance Of Covid – 19 Vaccine Related Adverse Events/ Side- Effects Among General Public In Dakshina Kannada." International Journal in Pharmaceutical Sciences 1, no. 11 (2023): 378–84. https://doi.org/10.5281/zenodo.10154149.

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The widespread distribution of COVID-19 vaccines has been a critical public health measure in mitigating the impact of the pandemic. Monitoring vaccine safety and understanding the prevalence of vaccine-related adverse events and side effects is essential for maintaining public trust and ensuring effective vaccination campaigns. This study was aimed to investigate the prevalence of adverse events and side effects associated with COVID-19 vaccinations among the general public&nbsp; &nbsp;in the Dakshina Kannada region. The data were gathered from a convenience sample of 1000 people each from th
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14

ESLAMI, Behnaz, Mehdi HABIBZADEH MOTLAGH, Zahra REZAEI, Mohammad ESLAMI, and Mohammad AMIN AMINI. "UNSUPERVISED DYNAMIC TOPIC MODEL FOR EXTRACTING ADVERSE DRUG REACTION FROM HEALTH FORUMS." Applied Computer Science 16, no. 1 (2020): 41–59. http://dx.doi.org/10.35784/acs-2020-04.

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The relationship between drug and its side effects has been outlined in two websites: Sider and WebMD. The aim of this study was to find the association between drug and its side effects. We compared the reports of typical users of a web site called: "Ask a patient" website with reported drug side effects in reference sites such as Sider and WebMD. In addition, the typical users' comments on highly-commented drugs (Neurotic drugs, Anti-Pregnancy drugs and Gastrointestinal drugs) were analyzed, using deep learning method. To this end, typical users' comments on drugs' side effects, during last
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15

Cookson, John. "Side-effects of Antidepressants." British Journal of Psychiatry 163, S20 (1993): 20–24. http://dx.doi.org/10.1192/s0007125000292325.

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The adverse effects of antidepressants include their pharmacological side-effects, toxic effects, interactions with other drugs, and symptoms occurring during their withdrawal. The focus of this paper is on the pharmacological side-effects.
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16

Kovalenko, E. I., I. B. Kononenko, A. V. Snegovoi, O. P. Grebennikova, and L. V. Manzyuk. "Adverse effects of adjuvant endocrine therapy." Medical Council, no. 10 (July 19, 2018): 64–69. http://dx.doi.org/10.21518/2079-701x-2018-10-64-69.

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Hormonal therapy is a highly effective and well tolerable treatment of hormone-responsive breast cancer. However, it has some side effects that can affect quality of life and lead to treatment discontinuation. Common side effects of tamoxifen and aromatase inhibitors are discussed in this article: menopausal, gynecological symptoms, cardiovascular and musculoskeletal adverse events. Some of them are preventable and manageable. In order to maintain good quality of life during treatment the oncologists should pay more attention to the side effects that lead to it’s deterioration and not be too a
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17

Brown, RB, J. Levin, and A. Morris. "Adverse effects of antibiotics." Journal of the American Podiatric Medical Association 79, no. 10 (1989): 500–504. http://dx.doi.org/10.7547/87507315-79-10-500.

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Adverse reactions to antibiotics comprise a number of classes of reactions, including toxicity, side effects, and allergy. Each one of these differs in its implication for treatment of the patient. The authors discuss some of the more common and unusual reactions to antibiotics frequently used in the practice of podiatric medicine.
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18

Attardo, Silvia, Olimpia Musumeci, Daniele Velardo, and Antonio Toscano. "Statins Neuromuscular Adverse Effects." International Journal of Molecular Sciences 23, no. 15 (2022): 8364. http://dx.doi.org/10.3390/ijms23158364.

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Statins are drugs widely prescribed in high-risk patients for cerebrovascular or cardiovascular diseases and are, usually, safe and well tolerated. However, these drugs sometimes may cause neuromuscular side effects that represent about two-third of all adverse events. Muscle-related adverse events include cramps, myalgia, weakness, immune-mediated necrotizing myopathy and, more rarely, rhabdomyolysis. Moreover, they may lead to peripheral neuropathy and induce or unmask a preexisting neuromuscular junction dysfunction. A clinical follow up of patients assuming statins could reveal early side
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19

Nehad, J. Ahmed. "GASTROINTESTINAL SIDE EFFECTS OF ANTIFUNGALS: A NARRATIVE REVIEW." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 04 (2019): 7302–7. https://doi.org/10.5281/zenodo.2633205.

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<strong><em>Introduction</em></strong><em>: Antifungals are used to treat different fungal infections which affect different body part. Systemic antifungals may result in many adverse effects especially gastrointestinal adverse effects. The Aim of these study is to illustrate the common and serious adverse effects of antifungals on gastrointestinal system.</em> <strong><em>Methodology</em></strong><em>: contains 3 parts, searching Micromedex, searching the Web of Science and searching Cochrane library for the adverse effects of antifungals.&nbsp; </em> <strong><em>Results and Discussion</em></
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20

Korah, Mejo C., Junaid Rahman Pv, R. Rajeswari, Ahana Behanan, Elizabeth Phoeba Paul, and T. Sivakumar. "ADVERSE EFFECTS AND SIDE EFFECTS ON VITAMIN THERAPY: A REVIEW." Asian Journal of Pharmaceutical and Clinical Research 10, no. 5 (2017): 19. http://dx.doi.org/10.22159/ajpcr.2017.v10i5.17014.

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Vitamins are essential to our day to day life. Its shortage in our body can cause many disorders, decreased enzyme activities also affects the genetic factors. Vitamins should be supplied through the diet in the required amount. If it is not supplied properly, vitamin tablets will be prescribed. And also vitamin tablets are the co-medication for therapies like anticancer, anti tubercular, anti viral anti HIV treatments. Many news papers reported that vitamin therapies are causing major health problems like nephro/ urolithiasis, it can increases mortality rates in smokers by increasing the risk
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21

Pepperell, Roger J. "Beneficial and adverse side‐effects of hormonal contraception." Medical Journal of Australia 144, no. 4 (1986): 169–70. http://dx.doi.org/10.5694/j.1326-5377.1986.tb128348.x.

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22

Pfiffner, Linda J., and George J. DuPaul. "Possible Adverse Side Effects of School Behavioral Interventions." ADHD Report 26, no. 1 (2018): 10–13. http://dx.doi.org/10.1521/adhd.2018.26.1.10.

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23

Stojic-Vukanic, Zorica, Nevena Arsenovic-Ranin, Jelena Antic-Stankovic, and Marina Milenkovic. "Adverse side-effects of biological agents: Hypersensitivity reactions." Arhiv za farmaciju 64, no. 6 (2014): 457–72. http://dx.doi.org/10.5937/arhfarm1406457s.

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24

O'Donnell, James. "Adverse Effects of Corticosteroids." Journal of Pharmacy Practice 2, no. 4 (1989): 256–66. http://dx.doi.org/10.1177/089719008900200410.

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Currently, adrenal corticosteroids (steroids) are used for a wide variety of clinical conditions. Steroids are known to cause many pathologic effects, including chemically induced diabetes, psychological changes, musculoskeletal (including avascular) necrosis, suppression of the adrenals, and significant effects on the eye. Considering the important risk factors involved with the use of these toxic, yet essential medications, pharmacists have a serious responsibility to monitor their use for indications, dosage, interactions, and side effects.
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25

Carter, Barry L., Jerold C. Woodhead, Katherine J. Cole, and Gary Milavetz. "Gastrointestinal Side Effects with Erythromycin Preparations." Drug Intelligence & Clinical Pharmacy 21, no. 9 (1987): 734–38. http://dx.doi.org/10.1177/106002808702100914.

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This study was designed to determine the incidence and severity of gastrointestinal (GI) side effects in patients taking erythromycin. More patients complained of GI side effects with the enteric-coated tablet (70.8 percent) than with the stearate (51.4 percent) or the ethylsuccinate (48.9 percent) salts. The enteric-coated tablet was associated with a higher incidence of individual adverse reactions; more patients discontinued it because of adverse GI effects. These data demonstrate a high incidence of GI side effects to erythromycin. Additionally, GI side-effect incidence appears to be highe
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26

Hirai, Risako, Motoki Kei, and Yoshihiro Uesawa. "Comprehensive Analysis of Strong Opioid Side Effects in Palliative Care Using the SIDER Database." Journal of Clinical Medicine 14, no. 5 (2025): 1410. https://doi.org/10.3390/jcm14051410.

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Background/Objectives: There exist multiple opioid-based treatments in palliative care, each with distinct side effect profiles. When adverse events occur, switching opioids can help maintain effective pain management. However, owing to limited clinical evidence, no comprehensive guidelines exist for opioid switching. This study employed the Side Effect Resource (SIDER) database, which aggregates adverse event data from clinical trials and package inserts, to analyze the side effects of five commonly used “strong opioids” in palliative care in Japan, namely morphine, fentanyl, oxycodone, hydro
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27

Gautam, Sachin, Simerjot Kaur, Dalip Gupta, and Vimal Bharti. "Side Effect Profiling of Anti-Retroviral (ART) Drugs." Himalayan Journal of Medicine and Surgery 02, no. 01 (2021): 1–5. https://doi.org/10.47310/hjms.2021.v02i01.014.

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Background: There is a growing need to evaluate adverse effects of ART on patients, so it is important to document adverse effects of antiretroviral therapy for early diagnosis, proper management and prevention in future and hence this was planned to study the toxicity profile towards the commonly used first-line antiretroviral drugs. Material and Methods: This study was conducted in a tertiary care hospital of Shimla, Himachal Pradesh from 1st July 2019 to 30th June 2020. All consecutive patients presenting in the ART center of IGMC Shimla were recruited. A detailed history with duration of s
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Moreira, Bernardo, Sigride Thomé-Souza, and Kette Valente. "Late side-effects of valproate and lamotrigine." Journal of Epilepsy and Clinical Neurophysiology 13, no. 4 (2007): 187–89. http://dx.doi.org/10.1590/s1676-26492007000400008.

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Lamotrigine (LTG) is a generally well-tolerated antiepileptic drug with broad-spectrum efficacy in several forms of partial and generalized epilepsy. Adverse effects of lamotrigine are usually associated with introduction and titration. This risk increases in children and in the co-medication with valproate. Herein, we report four patients with late adverse-effects, under the co-medication valproate and LTG, not related to drug introduction or titration. This study demonstrates that late side-effects without apparent etiology in children, adolescents and adults in chronic use of LTG, especiall
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Chen, Y. H., Y. T. Shih, C. S. Chien, and C. S. Tsai. "Predicting adverse drug effects: A heterogeneous graph convolution network with a multi-layer perceptron approach." PLOS ONE 17, no. 12 (2022): e0266435. http://dx.doi.org/10.1371/journal.pone.0266435.

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We apply a heterogeneous graph convolution network (GCN) combined with a multi-layer perceptron (MLP) denoted by GCNMLP to explore the potential side effects of drugs. Here the SIDER, OFFSIDERS, and FAERS are used as the datasets. We integrate the drug information with similar characteristics from the datasets of known drugs and side effect networks. The heterogeneous graph networks explore the potential side effects of drugs by inferring the relationship between similar drugs and related side effects. This novel in silico method will shorten the time spent in uncovering the unseen side effect
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Tejaswini, S. Usha, Padmini Gangadhar, and Srinivasan Kavitha. "Ocular Adverse Effects of Antiglaucoma Medications." Delhi Journal of Ophthalmology 33, no. 2 (2023): 118–20. https://doi.org/10.4103/dljo.dljo_90_23.

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Antiglaucoma medications form the cornerstones of glaucoma management, often preferred as the first line. However, the adverse reactions associated with topical antiglaucoma medications are quite common and could be a cause for poor compliance. The adverse reactions of the topical antiglaucoma medications can either be localized to the eye and periorbital area or can be systemic. Ocular side effects can result either from the preservatives such as benzalkonium chloride or could be a side effect of the drug molecule itself. They could cause significant discomfort to the patient and hence knowin
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31

Cheon, Dae Young, and Sang-Ho Jo. "Adverse effects of statin therapy and their treatment." Cardiovascular Prevention and Pharmacotherapy 4, no. 1 (2022): 1–6. http://dx.doi.org/10.36011/cpp.2022.4.e4.

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Statins are one of the most widely used drugs worldwide as first-line drugs for the treatment of hyperlipidemia and the prevention and treatment of cardiovascular diseases. Most of the side effects of statins are known to be mild, and mainly hepatotoxicity and various muscle symptoms are known. Recently, there have been studies on concerns about an increase in the incidence of diabetes after using statins, but it was found that the benefits sufficiently outweigh the risk of side effects. Therefore, the use of statins in the appropriate group should be actively performed, and it seems that the
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32

Steinhart, Yael, Ziv Carmon, and Yaacov Trope. "Warnings of Adverse Side Effects Can Backfire Over Time." Psychological Science 24, no. 9 (2013): 1842–47. http://dx.doi.org/10.1177/0956797613478948.

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33

Valejo Coelho, Margarida Moura, and Margarida Apetato. "The dark side of the light: Phototherapy adverse effects." Clinics in Dermatology 34, no. 5 (2016): 556–62. http://dx.doi.org/10.1016/j.clindermatol.2016.05.005.

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34

Aubin, François, Franck Carbonnel, and Daniel Wendling. "The complexity of adverse side-effects to biological agents." Journal of Crohn's and Colitis 7, no. 4 (2013): 257–62. http://dx.doi.org/10.1016/j.crohns.2012.06.024.

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35

Veerendar, Chitte, and Shwetha Kumari G. "Averse Drug Effects of Atypical Antipsychotics in Schizophrenia Cases." International Journal of Pharmaceutical and Clinical Research 16, no. 4 (2024): 311–15. https://doi.org/10.5281/zenodo.11176468.

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<strong>Introduction:&nbsp;</strong>Atypical antipsychotics are more preferable than typical antipsychotics due to their superior safety profile and lower likelihood of causing extrapyramidal side effects. The occurrence of adverse drug reactions from atypical antipsychotics has a detrimental effect on the overall quality of life and need specific care over the course of therapy. The current research aimed to evaluate the effectiveness of atypical antipsychotics and their influence on individuals with schizophrenia.&nbsp;<strong>Material and Methods:</strong>&nbsp;We included a cohort of 120 i
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G, Siddesha, Justina M. Steefan, and A. Naveen. "Adverse Effects of Antipsychotic Drugs - A Review." International Journal of Research and Review 10, no. 9 (2023): 153–56. http://dx.doi.org/10.52403/ijrr.20230916.

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Antipsychotic drugs which are also known as Neuroleptics are group of psychotropic drugs or psychopharmacological agents1 that are primarily used to manage psychoses including delusions, hallucinations, paranoia, or disordered thought. Besides their antipsychotic action, they had been reported to have some adverse effects which can be seen in Cardiovascular system, Metabolic system, Skeletal and Muscular system, Cognitive and Emotional side effects, and Sexual dysfunction. These adverse effects were mainly observed when they used for longer duration or taken in larger doses or with sudden chan
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37

Licht, C. "Rare adverse effects of Electro Convulsive Therapy." European Psychiatry 66, S1 (2023): S1017—S1018. http://dx.doi.org/10.1192/j.eurpsy.2023.2161.

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IntroductionECT’s most common side effects are headache, memory impairment, and cardiovascular changes [1]. We report the unusual case of unilateral eyelid swelling and cheek flushing as a side effect of ECT in a depressed but otherwise healthy patient.ObjectivesThe patient is a 53-year-old woman with a recurrent depressive disorder for 15 years with a current major depressive episode without psychotic symptoms. With therapy resistance to mirtazapine (60 mg/d) and lithium (675 mg/d; 0.75 mmol/l), an ECT series with a total of seven sessions were performed. Treatment was performed with right un
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Cretu, Ioana, Bogdan Cretu, Catalin Cirstoiu, et al. "Rheumatological Adverse Events Following Immunotherapy for Cancer." Medicina 58, no. 1 (2022): 94. http://dx.doi.org/10.3390/medicina58010094.

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Background and Objectives: The occurrence of rheumatological side effects in a patient after receiving immunotherapy for cancer is becoming increasingly common. Oncologists often fail to diagnose and refer affected patients to rheumatologists. This paper presents the various rheumatological adverse events that occur after immunotherapy in patients as well as their treatment and evolution. Materials and Methods: A total of 36 patients were monitored between November 2018 and March 2020. The oncologist monitoring the immunotherapy-treated patients identified the occurrence of musculoskeletal sid
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Karmel, Sara, and Željko Jovanović. "Some factors influencing underreporting of suspected vaccine side effects." Paediatria Croatica 67, no. 3-4 (2023): 65–70. http://dx.doi.org/10.13112/pc.2023.11.

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Reporting suspected adverse reactions allows monitoring of vaccine safety and identification of new, rare or serious adverse reactions that may not have been observed during clinical trials. When an adverse reaction is suspected, health professionals have a legal obligation and patients have the opportunity to report it to the relevant bodies such as the Croatian Agency for Medicinal Products and Medical Devices in order to contribute to a broader understanding of the potential risks and benefits of vaccines. Improving patient education, communication, trust and empowerment may be key to encou
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Akcal, Omer, Semiha Bahceci Erdem, and Ilke Taskirdi. "A Rare Side Effect of IVIG: Diarrhea." Pediatric Academic Case Reports 1, no. 1 (2022): 17–20. http://dx.doi.org/10.61107/pacr.2022.012.

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Intravenous immunoglobulin (IVIG), which is primarily immunoglobulin G (IgG), is used in the treatment of many diseases. While it is generally well tolerated, some adverse effects may be seen in different systems during IVIG treatment. The adverse effects of IVIG infusion are typically mild and related to the infusion rate. The formation of the immunoglobulin aggregates that lead to the activation of the complement system can be prevented by decreasing the infusion rate, and mild adverse effects may be overcome. In rare cases, however, severe life-threatening adverse effects may develop, such
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Rakesh, Kumar, Anil Mini, Singh Parihar Durlav, Garhpale Anshul, Panda Sampurna, and Panda Babita. "A Cross-sectional Assessment of Gwalior Residents' Reports of Adverse Reactions to the COVID-19 Immunization." Indian Journal of Science and Technology 15, no. 44 (2022): 2386–92. https://doi.org/10.17485/IJST/v15i44.772.

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Abstract <strong>Objectives:</strong>&nbsp;Many people around the world are worried about the safety and adverse effects of the coronavirus SARS CoV2 vaccine. The study&rsquo;s goal was to document the side effects experienced by Gwalior residents who had received vaccinations. The other objective includes, to evaluate the potential risk factors associated with Covishield and Covaxin vaccination.&nbsp;<strong>Methods:</strong>&nbsp;Participants who had received one or both doses of any of the provided vaccines were surveyed using a cross-sectional survey (Covaxin, Covishield). The study enroll
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42

Mercadante, Sebastiano. "Opioid Analgesics Adverse Effects: The Other Side of the Coin." Current Pharmaceutical Design 25, no. 30 (2019): 3197–202. http://dx.doi.org/10.2174/1381612825666190717152226.

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Background: Opioids are the cornerstone of the management of cancer pain. However, the development of adverse effects may compromise the opioid response. They include nausea and vomiting, constipation, drowsiness, sleep disorders, cognitive dysfunction, myoclonus, pruritus, dysuria, dependence and the development of aberrant behaviors, respiratory depression, and some endocrine responses. Methods: The goal of this paper is to identify the most common opioid-related adverse effects, their pathophysiology, and proposing the possible treatments. This narrative review will describe how these adver
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43

Ziff, M. F. "Documented Clinical Side-Effects to Dental Amalgam." Advances in Dental Research 6, no. 1 (1992): 131–34. http://dx.doi.org/10.1177/08959374920060010601.

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Since all dental restorative materials are foreign substances, their potential for producing adverse health effects is determined by their relative toxicity and bioavailability, as well as by host susceptibility. Adverse health effects to dental restoratives may be local in the oral cavity or systemic, depending on the ability of released components to enter the body and, if so, on their rate of absorption. The medical scientific community is now in general agreement that patients with dental amalgam fillings are chronically exposed to mercury, that the average daily absorption of mercury from
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Xiang, Elaine, Jian Ni, Brett Glotzbecker, Jacob Laubach, Robert Soiffer, and Anne M. McDonnell. "Evaluating the adverse effects of melphalan formulations." Journal of Oncology Pharmacy Practice 25, no. 7 (2018): 1631–37. http://dx.doi.org/10.1177/1078155218804042.

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Introduction For multiple myeloma patients who respond to primary therapy, autologous hematopoietic stem cell transplant (HSCT) is considered standard of care with high-dose melphalan for transplant candidates. There are now two different melphalan formulations available, including a propylene glycol containing (PG-MEL) product and a propylene glycol-free (PG-free MEL) product. Although considered bioequivalent, there remains limited literature directly evaluating the adverse events between the two agents. We seek to assess the tolerability and severity of side effects between the two formulat
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Gherghel, Doina. "Systemic side effects of ocular medication – 4." Optician 2020, no. 11 (2020): 8393–1. http://dx.doi.org/10.12968/opti.2020.11.8393.

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Dr Doina Gherghel concludes her review of the adverse effects of ophthalmic drugs with a further look at intravitreal drugs and those used during surgical procedures (C 76604, one distance learning CET point suitable for optometrists and therapeutic optometrists)
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Georgiyeva, K., and P. Blake. "CARDIOVASCULAR SIDE EFFECTS OF COLON CANCER THERAPY." Sciences of Europe, no. 99 (August 22, 2022): 20–24. https://doi.org/10.5281/zenodo.7014308.

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Colon cancer and cardiovascular diseases present the major two causes of death worldwide, with colon cancer being the second most prevalent cancer in the United States. Furthermore, the treatment therapy used in different types of cancer often leads to cardiovascular side effects which affect the quality of life of patients receiving colon cancer treatment therapy. The field of cardio-oncology has emerged to study the cardiovascular side effects of cancer treatment therapy. The cardiovascular side effects of most used treatment therapies in colon cancer are discussed. This review studies the s
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Ryu, Hyewon. "Management of the adverse effects of targeted therapy for cancer." Journal of the Korean Medical Association 66, no. 2 (2023): 105–11. http://dx.doi.org/10.5124/jkma.2023.66.2.105.

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Background: Advances in genomics and molecular biology over the past 20 years have resulted in numerous approved molecular targeted cancer therapies. The two main approaches for targeted cancer therapy are monoclonal antibodies and small molecules. Targeted therapy is expected to exert few side effects, but a new class of toxicities has been reported. Thus, the classical chemotherapy-induced toxicities of alopecia, myelosuppression, mucositis, nausea, and vomiting have been replaced in patients receiving targeted therapies by dermatologic, cardiovascular, gastrointestinal, endocrine, ocular, a
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Khanday, Suheena, Mohd Afsahul Kalam, and Shameem Ahmad Rather. "ADVERSE EFFECT OF UNANI PHARMACOPOEIAL FORMULATION HABB-E-KARANJAWA." Indian Journal of Unani Medicine 15, no. 01 (2022): 73–75. http://dx.doi.org/10.53390/ijum.2022.15113.

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Pharmacovigilance (PV), which is also known as drug safety. It is the pharmacological science relating to the detection, assessment, understanding and prevention of adverse effects, particularly long term, and short term side effects of medicines [1]. The key role of this field of medicine is to ensure the safe reception of drugs, examining the adverse side effects reported by patients. The compound causing side effects in the drug need to be identified and the remedy to counteract the side effect should be explored. This study was carried out at Regional Research Institute of Medicine (RRIUM)
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Batishcheva, Galina A., Olga A. Zhdanova, Tatyana L. Nastausheva, and Yury N. Chernov. "Characteristics of adverse side effects of corticosteroid therapy in children with nephrotic syndrome and methods of pharmacological correction." Research Results in Pharmacology 5, no. (1) (2019): 37–43. https://doi.org/10.3897/rrpharmacology.5.33831.

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Introduction: The article discusses the issues of the long-term glucocorticosteroid therapy in children with nephrotic syndrome that results in severe adverse side effects. Methods: This retrospective study included 89 case reports of patients with nephrotic syndrome, aged 1–18, who received treatment at Voronezh Regional Pediatric Hospital №1 in 1999–2014. The children's BMI Z-score was calculated from neasured height and weight. The authors considered therapeutical complications revealed through clinical-laboratory and instrumentation examination. Results and discussion: Long-term administra
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Sarde, Atharva, Mayur Badgujar, Gargee Athayle, and Prof Shilpa Sondkar. "Predictive Analysis of Adverse Drug effects using Machine Learning." International Journal for Research in Applied Science and Engineering Technology 10, no. 12 (2022): 868–75. http://dx.doi.org/10.22214/ijraset.2022.48058.

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Abstract: The objective of this work is to develop machine learning (ML) methods that can accurately predict adverse drug reactions (ADRs) using databases like SIDER (Side Effect Research) and OFFSIDES (Government medical records). In this paper, three Machine Learning algorithms SVM (Support Vector Machine), Random Forest, and Gradient boosted trees are implemented on the datasets to predict various disorders caused due to adverse effects, and the performance is evaluated based on performance metrics such as average precision, recall, accuracy, f1 binary, f1 macro, and f1 micro. Finally, the
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