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1

POROMAA, INGER SUNDSTRÖM, and BIRGITTA SEGEBLADH. "Adverse mood symptoms with oral contraceptives." Acta Obstetricia et Gynecologica Scandinavica 91, no. 4 (2012): 420–27. http://dx.doi.org/10.1111/j.1600-0412.2011.01333.x.

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2

Corso, Diane M., Frank Pucino, James M. DeLeo, Karim A. Calis, and Joseph F. Gallelli. "Development of a Questionnaire for Detecting Potential Adverse Drug Reactions." Annals of Pharmacotherapy 26, no. 7-8 (1992): 890–96. http://dx.doi.org/10.1177/106002809202600704.

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OBJECTIVE: To develop a comprehensive list of symptoms categorized by body system as part of a questionnaire for detecting potential adverse drug reactions. DATA SOURCES: A preliminary list of symptoms in lay terminology was extracted from the “Side Effects” section of all drug monographs contained in the United States Pharmacopeia Dispensing Information (USP DI) computerized database ( Volume II, Advice for the Patient) using natural language processing software. The list was sorted alphabetically and duplicate terms were eliminated. Symptoms were then categorized by body system or anatomic r
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Key, Amanda, Addie Pederson, Jared Sant, and Coby Ray. "Teprotumumab-associated hearing-related adverse events." Southwest Respiratory and Critical Care Chronicles 12, no. 50 (2024): 24–29. http://dx.doi.org/10.12746/swrccc.v12i50.1261.

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This study aims to provide a review of the existing literature on teprotumumab (Tepezza)-associated hearing-related adverse effects. A review of PubMed and Embase was conducted using keywords “teprotumumab,” “tepezza,” “hearing disorder[s],” “hearing loss,” and “ototoxicity.” These search results were filtered to include all clinical trials, observational studies, case reports, and case series relevant to the topic of teprotumumab-associated hearing disorders. Data collection from the 15 included studies consisted of: sample size, number and percentage of hearing disorders reported, types of h
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Fromme, Erik K., Kristine M. Eilers, Motomi Mori, Yi-Ching Hsieh, and Tomasz M. Beer. "How Accurate Is Clinician Reporting of Chemotherapy Adverse Effects? A Comparison With Patient-Reported Symptoms From the Quality-of-Life Questionnaire C30." Journal of Clinical Oncology 22, no. 17 (2004): 3485–90. http://dx.doi.org/10.1200/jco.2004.03.025.

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Purpose Adverse events in chemotherapy clinical trials are assessed and reported by clinicians, yet clinician accuracy in assessing symptoms has been questioned. We compared patient reporting of eight symptoms using a validated instrument, the European Organization for the Research and Treatment of Cancer Quality-of-Life Questionnaire C30 (QLQ-C30 or QLQ) with physicians' reporting of the same symptoms in the study's adverse events log. Patients and Methods Thirty-seven men with metastatic, androgen-independent prostate cancer enrolled onto a phase II trial of weekly calcitriol and docetaxel c
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Aladwan, Shirin, Jennifer J. Harrison, David F. Blackburn, Jeff Taylor, Tom D. Blydt-Hansen, and Holly Mansell. "A Canadian Survey on Adverse Symptoms Experienced by Solid Organ Transplant Recipients." Progress in Transplantation 30, no. 3 (2020): 254–64. http://dx.doi.org/10.1177/1526924820933821.

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Introduction: Adverse symptoms experienced by solid organ transplant recipients remain largely unexplored despite their purported frequency. Objective: To characterize patient perspectives on adverse symptoms, identifying the most problematic symptoms and the perceived cause and treatability, and to evaluate their impact on quality of life (QoL) and medication adherence. Methods: An electronic survey was distributed to members of the Canadian Transplant Association, to characterize perceptions on symptom experience (Modified Transplant Symptom Occurrence and Distress Scale), and QoL (Short For
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LEVITAN, ROBERT D. "Do Adverse Life Events Trigger Atypical Symptoms?" American Journal of Psychiatry 165, no. 4 (2008): 533. http://dx.doi.org/10.1176/appi.ajp.2008.07121958.

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Fernando, Regina. "Adverse physical symptoms in radiographers practising ultrasound." Radiography 2, no. 2 (1996): 91–97. http://dx.doi.org/10.1016/s1078-8174(96)90001-2.

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Upthegrove, Rachel, Christine Chard, Lisa Jones, et al. "Adverse childhood events and psychosis in bipolar affective disorder." British Journal of Psychiatry 206, no. 3 (2015): 191–97. http://dx.doi.org/10.1192/bjp.bp.114.152611.

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BackgroundThere has been increasing interest in the association between childhood trauma and psychosis. Proposals for potential mechanisms involved include affective dysregulation and cognitive appraisals of threat.AimsTo establish if, within bipolar disorder, childhood events show a significant association with psychosis, and in particular with symptoms driven by dysregulation of mood or with a persecutory content.MethodData on lifetime-ever presence of psychotic symptoms were determined by detailed structured interview with case-note review (n= 2019). Childhood events were recorded using a s
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Ritsner, M., I. Modai, O. Rivkin, E. Bystrov, J. Nehamkin, and A. Ponizovsky. "Distress Scale for Adverse Symptoms: A new instrument for measuring the relationship between adverse drug symptoms and associated distress." European Neuropsychopharmacology 9 (September 1999): 258. http://dx.doi.org/10.1016/s0924-977x(99)80258-2.

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10

Seresirikachorn, K., J. Mullol, K. Limitlaohaphan, V. Asvapoositkul, and K. Snidvongs. "Leukotriene receptor antagonist addition to intranasal steroid: systematic review and meta-analysis." Rhinology journal 59, no. 1 (2021): 2–9. http://dx.doi.org/10.4193/rhin20.126.

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Background: Intranasal corticosteroids (INCS) and leukotriene receptor antagonist (LTRA) have different mechanisms of action. The combination of INCS and LTRA (INCS+LTRA) are utilized to control the allergic rhinitis (AR) symptoms. The effects of this com- bination have not been made evident yet. Methodology: Randomized controlled trials studying the effects of INCS+LTRA vs INCS in monotherapy on rhinoconjunctivitis symptoms in patients with AR were included. Data were pooled for meta-analysis. The outcomes were nasal symptoms, ocular symptoms, disease-specific quality of life (QOL), and adver
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Shenoy, B., N. McArdle, J. Walsh, et al. "O006 Major adverse cardiovascular events in severe Obstructive Sleep Apnoea: Associations with symptom subtypes and symptom burden." Sleep Advances 4, Supplement_1 (2023): A2—A3. http://dx.doi.org/10.1093/sleepadvances/zpad035.006.

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Abstract Background Obstructive sleep apnoea (OSA) is a heterogeneous disorder with certain phenotypes at increased risk of major adverse cardiovascular events (MACE). We investigated whether symptom subtypes and/or symptom burden are useful predictors of MACE risk in severe OSA. Method In a longitudinal sleep clinic cohort with apnoea-hypopnoea index ≥30 events/hour (n=1767), we investigated 19 OSA-related symptoms across four symptom domains (upper airway [UA], insomnia and disturbed sleep, morning, and daytime sleepiness) and the Epworth Sleepiness Scale score. Latent class analysis identif
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Lee, Eun Hye, and Yong Hyun Jang. "Cutaneous adverse drug reactions." Journal of the Korean Medical Association 66, no. 1 (2023): 41–47. http://dx.doi.org/10.5124/jkma.2023.66.1.41.

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Background: Cutaneous adverse drug reactions are common and produce easily identifiable clinical symptoms. These may range from mild maculopapular rashes to severe reactions associated with systemic disease.Current Concepts: The most common presentation of a drug eruption is in the form of a maculopapular rash or exanthematous skin eruption, followed by fixed drug eruptions and urticaria. Severe cutaneous adverse drug reactions include Stevens-Johnson syndrome/toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug-induced hypersensitivity syndrome/drug reaction with e
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Zhong, Xiaobo, Emerson A. Lim, Dawn L. Hershman, et al. "ReCAP: Identifying Severe Adverse Event Clusters Using the National Cancer Institute’s Common Terminology Criteria for Adverse Events." Journal of Oncology Practice 12, no. 3 (2016): 245–46. http://dx.doi.org/10.1200/jop.2015.006106.

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CONTEXT & QUESTION ASKED: Exploring the relationship among adverse events is important because those that arise from a common mechanism are amenable to a common intervention, which can improve symptom management, quality of life, and treatment adherence. To date, symptom cluster studies have used patient-reported data, which are not always available in clinical trials. In this study, we proposed using the National Cancer Institute Common Terminology Criteria for Adverse Events (CTCAE) to identify adverse event clusters because the CTCAE are collected as standard practice and can therefore
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Bower, Julienne E. "Behavioral Symptoms in Patients With Breast Cancer and Survivors." Journal of Clinical Oncology 26, no. 5 (2008): 768–77. http://dx.doi.org/10.1200/jco.2007.14.3248.

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Behavioral symptoms are a common adverse effect of breast cancer diagnosis and treatment and include disturbances in energy, sleep, mood, and cognition. These symptoms cause serious disruption in patients' quality of life and may persist for years after treatment. Patients need accurate information about the occurrence of these adverse effects as well as assistance with symptom management. This review considers four of the most common behavioral sequelae of breast cancer, namely fatigue, sleep disturbance, depression, and cognitive impairment. Research on the prevalence, mechanisms, and treatm
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Hadji, P. "Menopausal symptoms and adjuvant therapy-associated adverse events." Endocrine Related Cancer 15, no. 1 (2008): 73–90. http://dx.doi.org/10.1677/erc-07-0193.

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Carver, Charles S. "Generalization, Adverse Events, and Development of Depressive Symptoms." Journal of Personality 66, no. 4 (1998): 607–19. http://dx.doi.org/10.1111/1467-6494.00026.

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Pincus, T., and N. Steen Krogh. "FRI0587 A NEW APPROACH TO EARLY DETECTION OF ADVERSE EVENTS OF HIGH-RISK MEDICATIONS USING A STRUCTURED, STANDARD, PROTOCOL DRIVEN WEEKLY REMOTE ELECTRONIC MDHAQ 60-SYMPTOM CHECKLIST." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 898–99. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4942.

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Background:A multidimensional health assessment questionnaire (MDHAQ) includes RAPID3, which distinguishes active from control treatments in rheumatoid arthritis clinical trials, and documents change comparably to disease-specific indices in all diseases studied. The MDHAQ also includes a standard, structured 60-symptom checklist, to recognize comorbidities, provide a review of systems, and serve on a fibromyalgia assessment screening tool (FAST3) as a clue to identify patients with fibromyalgia. A new MDHAQ application is to recognize adverse events to high-risk medications on a standard, str
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Friedlander, Michael Leonard, Martin Stockler, Rachel O’Connell, et al. "Symptom Burden and Outcomes of Patients With Platinum Resistant/Refractory Recurrent Ovarian Cancer: A Reality Check." International Journal of Gynecologic Cancer 24, no. 5 (2014): 857–64. http://dx.doi.org/10.1097/igc.0000000000000147.

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BackgroundThe aim of chemotherapy in patients with platinum resistant ovarian cancer is palliation. Patients’ experience of symptoms is not well documented, and the impact of treatment on symptoms has not been evaluated in clinical trials. We report symptom burden and treatment outcomes from stage 1 of the Gynecological Cancer Intergroup (GCIG) Symptom Benefit Study.MethodsOne hundred twenty-six patients receiving palliative chemotherapy completed 5 validated health-related quality-of-life questionnaires before starting treatment and before each cycle. They also reported their expected and per
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Polimeni, Giovanni, Paola Cutroneo, Adele Gallo, Salvatore Gallo, Edoardo Spina, and Achille P. Caputi. "Rabeprazole and Psychiatric Symptoms." Annals of Pharmacotherapy 41, no. 7-8 (2007): 1315–17. http://dx.doi.org/10.1345/aph.1k134.

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Objective: To report the case of a patient who developed marked anxiety associated with episodes of panic attacks after starting rabeprazole therapy. Case Summary: An otherwise healthy 55-year-old woman was prescribed rabeprazole 20 mg/day administered in the morning tor persistent symptoms of dyspepsia. Ten days later, she presented with a 7 day history of marked anxiety associated with panic attacks, night terror (pavor nocturnus), episodic mental confusion, and attention deficit. Within 2 days of discontinuing rabeprazole, the patient recovered completely from the neuropsychiatric manifesta
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Collomb, Bastien, Amélie Dubromel, Anne Gaëlle Caffin, et al. "Assessment of Patient Reported Outcomes (PROs) in Outpatients Taking Oral Anticancer Drugs Included in the Real-Life Oncoral Program." Cancers 14, no. 3 (2022): 660. http://dx.doi.org/10.3390/cancers14030660.

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Background In previous studies, patient-reported outcomes (PROs) have been shown to improve survival in cancer patients. The aim of the present study was to assess symptoms potentially related to adverse events experienced by cancer outpatients treated by oral anticancer agents (OAAs) using PROs. Methods Between September 2018 and May 2019, outpatients starting OAAs were included in a 12-week follow-up to assess 15 symptoms listed in the National Cancer Institute PRO Common Terminology Criteria for Adverse Events, using a 5-point scale of severity or frequency. Patients were requested to alert
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Khan, Qamar J., Anne P. O'Dea, and Priyanka Sharma. "Musculoskeletal Adverse Events Associated with Adjuvant Aromatase Inhibitors." Journal of Oncology 2010 (2010): 1–8. http://dx.doi.org/10.1155/2010/654348.

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Musculoskeletal symptoms including arthralgia and myalgia occur frequently in aging women, particularly during the transition to menopause, when plasma estrogens precipitously decline. In postmenopausal women (PMW) with breast cancer, third-generation aromatase inhibitors (AIs) as adjuvant hormonal therapy have proven to be more effective, and to have a more predictable side effect profile, than tamoxifen. However, AIs further reduce plasma estrogens in PMW, exacerbating musculoskeletal symptoms. Clinical trial data have shown significantly higher incidences of arthralgia and myalgia with AIs
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St. George, E. J., J. Kudhail, J. Perks, and P. N. Plowman. "Acute symptoms after gamma knife radiosurgery." Journal of Neurosurgery 97 (December 2002): 631–34. http://dx.doi.org/10.3171/jns.2002.97.supplement_5.0631.

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Object. The purpose of this study was to examine the widely held assumption that early-onset symptoms after gamma knife radiosurgery (GKS) are uncommon. The study was designed to include all types of morbidity and not just those that lead to neurological dysfunction. It was hoped that the results of the study could lead to a more rational follow-up protocol. Methods. Data regarding adverse events were collected prospectively (within 2–3 weeks post-GKS) by telephone interview from 47 of the first 65 patients who could be reached. Immediate adverse events were defined as any new or unexpected sy
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Schroeder, K., S. Abu Mehsen, I. Castrejon, and T. Pincus. "FRI0517 POSSIBLE EARLY DETECTION OF ADVERSE EVENTS USING A STRUCTURED, STANDARD, 60-SYMPTOM CHECKLIST ON A MULTIDIMENSIONAL HEALTH ASSESSMENT QUESTIONNAIRE (MDHAQ)." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 857.2–858. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4771.

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Background:Adverse events of medications are reported to account for 5% of hospital admissions in the USA, including 10% in the elderly, despite extensive warnings to patients by health professionals and pharmacies concerning the problem. Some adverse events are relatively obvious, such as a severe rash or severely abnormal laboratory test. However, many adverse events are common symptoms, such as headache or fatigue, which may not necessarily be recognized as adverse events, particularly in elderly patients with many comorbidities. In clinical trials and other clinical research, a structured,
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Dr., Kyoung Suk Lee. "A Study of Heart failure events of survival as a Composite of Heart Failure, Physical and Depressive Symptoms." International Journal for Indian Science and Research Volume-1, Issue-3 (2022): 14–25. https://doi.org/10.5281/zenodo.7109353.

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Heart failure (HF) is a growing healthcare concern associated with adverse issues and stunning healthcare expenditures. In addition to traditional threat factors (e.g., age and comorbidities), cerebral status is honoured as a significant predictor of issues. Depressive symptoms are related to poor prognostic and quality of life in cases with HF. therefore, it's important for health care providers to fete and manage depressive symptoms meetly in the HF population. Depressive symptoms are common in cases with HF, with a frequency from 30 to 51. This large variability might be related to the
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Brasić, James Robert, Jacqueline Y. Barnett, Brian B. Sheitman, et al. "Behavioral Effects of Clomipramine on Prepubertal Boys With Autistic Disorder and Severe Mental Retardation." CNS Spectrums 3, no. 10 (1998): 39–46. http://dx.doi.org/10.1017/s1092852900006647.

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AbstractIn an open nonblind clinical trial, clomipramine was administered to five previously medicated prepubertal boys with autistic disorder and severe mental retardation unmanageable due to behavior and motor problems. Although all five boys initially displayed marked behavioral symptom reduction, they developed behavioral newotoxicity necessitating discontinuation of clomipramine for all five and immediate hospitalization for three. Serious adverse effects included increased seizure frequency and symptoms of a serotonin syndrome. Our findings indicate that clomipramine enhances adaptive be
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Maguire, Roma, Cees van Berkel, Julie Cowie, Robert L. Blake, and Nora Kearney. "Predictive modeling of adverse events in chemotherapy." Journal of Clinical Oncology 30, no. 15_suppl (2012): e19617-e19617. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e19617.

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e19617 Background: Patients with cancer receiving chemotherapy are at risk of developing severe or life threatening adverse events (AEs). The aim of this study was to develop and test a risk model for six common toxicities based on a detailed analysis of daily self-reported symptoms. The retrospective study was performed on a data set of 33 breast cancer patients who self reported symptoms over multiple therapy cycles. The monitored symptoms were diarrhoea, hand-foot syndrome, mucositis, nausea, vomiting and fatigue. Methods: The data analysis focused on four toxicity aspects: the occurrence p
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Weber, Cynthia A., Megan R. Leloux, Barry L. Carter, Karen B. Farris, and Yinghui Xu. "Reduction in Adverse Symptoms as Blood Pressure Becomes Controlled." Pharmacotherapy 28, no. 9 (2008): 1104–14. http://dx.doi.org/10.1592/phco.28.9.1104.

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Oka, Takakazu, Yoko Tamagawa, Sota Hayashida, Yuko Kaneda, Naoki Kodama, and Sadatoshi Tsuji. "Rikkunshi-to attenuates adverse gastrointestinal symptoms induced by fluvoxamine." BioPsychoSocial Medicine 1, no. 1 (2007): 21. http://dx.doi.org/10.1186/1751-0759-1-21.

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&NA;. "Ebastine: alleviates symptoms of hayfever without significant adverse effects." Inpharma Weekly &NA;, no. 725 (1990): 6–7. http://dx.doi.org/10.2165/00128413-199007250-00013.

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Hogenauer, Alfred F., and Matthew Devine. "Adverse reaction to rifampin mimicking symptoms of pulmonary tuberculosis." American Journal of Health-System Pharmacy 52, no. 20 (1995): 2339–40. http://dx.doi.org/10.1093/ajhp/52.20.2339.

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Samuelsson, Karin, and Erik Änggård. "Prolonged Symptoms of Brain Dysfunction- Adverse Effect of Levodopa." Acta Medica Scandinavica 200, no. 1-6 (2009): 143–44. http://dx.doi.org/10.1111/j.0954-6820.1976.tb08211.x.

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Flowers, Nicole T., Valerie J. Edwards, Robert F. Anda, and Vincent J. Felitti. "508 Adverse Childhood Experiences and Gastrointestinal Symptoms in Adulthood." Gastroenterology 138, no. 5 (2010): S—73. http://dx.doi.org/10.1016/s0016-5085(10)60334-4.

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Korlipara, Krishnarao, Susan E. Gould, Natalie A. Taylor, and Anthony Chandler. "Serotonin antagonism reduces the adverse symptoms of beta blockade." Cardiovascular Drugs and Therapy 4, no. 1 (1990): 127–31. http://dx.doi.org/10.1007/bf00053444.

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Bhavnani, Suresh K., Weibin Zhang, Sandra Hatch, Randall Urban, and Christopher Tignanelli. "364 Identification of Symptom-Based Phenotypes in PASC Patients through Bipartite Network Analysis: Implications for Patient Triage and Precision Treatment Strategies." Journal of Clinical and Translational Science 6, s1 (2022): 68. http://dx.doi.org/10.1017/cts.2022.207.

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OBJECTIVES/GOALS: Approximately 10% of COVID-19 patients experience multiple symptoms weeks and months after the acute phase of infection. Our goal was to use advanced machine learning methods to identify PASC phenotypes based on their symptom profiles, and their association with critical adverse outcomes, with the goal of designing future targeted interventions. METHODS/STUDY POPULATION: Data. All COVID-19 outpatients from 12 University of Minnesota hospitals and 60 clinics. Independent variables consisted of 20 CDC-defined PASC symptoms extracted from clinical notes using NLP. Covariates inc
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Cont, Celine, Annaliis Lehto, Nathalie Stute, et al. "Safety of Deep Repetitive Transcranial Magnetic Stimulation (drTMS) against Medical Refractory Symptoms in Parkinson Syndromes: First German Real-World Data with a Specific H5 Coil." Neurology International 14, no. 4 (2022): 1024–35. http://dx.doi.org/10.3390/neurolint14040082.

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So far, deep repetitive transcranial magnetic stimulation (drTMS) has shown promising results as an add-on treatment for Parkinson’s disease (PD) but not for non-idiopathic Parkinson Syndromes (PS). We aimed to investigate the safety and feasibility of drTMS application in patients with different Parkinson Syndromes and medical refractory symptoms. Multifaceted real-world data (n = 21) were retrospectively analyzed regarding adverse effects as well as short-term effects of the drTMS treatment on patients’ self-rated symptom severity and motor, cognitive, and emotional functions. The drTMS trea
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Keller, Matthew C., and Randolph M. Nesse. "The evolutionary significance of depressive symptoms: Different adverse situations lead to different depressive symptom patterns." Journal of Personality and Social Psychology 91, no. 2 (2006): 316–30. http://dx.doi.org/10.1037/0022-3514.91.2.316.

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D’Andrea, Mark A., and G. Kesava Reddy. "Adverse Health Complaints of Adults Exposed to Benzene After a Flaring Disaster at the BP Refinery Facility in Texas City, Texas." Disaster Medicine and Public Health Preparedness 12, no. 2 (2017): 232–40. http://dx.doi.org/10.1017/dmp.2017.59.

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AbstractObjectiveThe objective of this study was to assess the adverse health symptoms experienced by adult subjects who were exposed to benzene after a flaring disaster at the BP refinery in Texas City, Texas.MethodsA total of 2162 adults aged 18 years or older and exposed to benzene were included. Using the patients’ medical charts, we collected and analyzed data on health complaints as well as the patients’ serum levels of beta-2-microglobulin and urinary excretion of phenol.ResultsA total of 11,368 health symptom complaints were reported in 2162 adults exposed to benzene. Neurological symp
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Zoorob, Dani, Amanda S. Deis, and Kathryn Lindsay. "Refractory Sexual Arousal Subsequent to Sacral Neuromodulation." Case Reports in Obstetrics and Gynecology 2019 (April 2, 2019): 1–4. http://dx.doi.org/10.1155/2019/7519164.

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Background. Sacral neuromodulation has become a widely used treatment for lower urinary tract symptom and dysfunction. It has been observed to benefit sexual function in the domains of arousal and desire. Studies have yet to report markedly increased arousal symptoms as an adverse effect. Case. We present the case of a 57-year-old woman who developed symptomatic persistent genital arousal following implantation of a neuromodulator. Despite device reprogramming, a trial of the device being shut off, and eventual device removal, she continued to have residual new-onset undesired genital hyper-ar
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Matthews, Julie S., and James B. Adams. "Ratings of the Effectiveness of 13 Therapeutic Diets for Autism Spectrum Disorder: Results of a National Survey." Journal of Personalized Medicine 13, no. 10 (2023): 1448. http://dx.doi.org/10.3390/jpm13101448.

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This study presents the results of the effectiveness of 13 therapeutic diets for autism spectrum disorder from 818 participants of a national survey, including benefits, adverse effects, and symptom improvements. The average Overall Benefit of diets was 2.36 (0 = no benefit, 4 = great benefit), which was substantially higher than for nutraceuticals (1.59/4.0) and psychiatric/seizure medications (1.39/4.0), p < 0.001. The average Overall Adverse Effects of diets was significantly lower than psychiatric/seizure medications (0.10 vs. 0.93, p < 0.001) and similar to nutraceuticals (0.16). Au
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Desai, Saral, Tejasvi Kainth, Garima Yadav, et al. "Role of Psychosomatic Symptoms in COVID-19 Vaccine Hesitancy." Vaccines 11, no. 5 (2023): 922. http://dx.doi.org/10.3390/vaccines11050922.

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Vaccination against COVID-19 is one of the highly effective preventative strategies to reduce morbidity and mortality associated with COVID-19 infection. The rapid approval of COVID-19 vaccination due to the raging pandemic, media coverage, anti-vaccination groups, and concerns about adverse effects associated with vaccination has given rise to COVID-19 vaccine hesitancy. Current evidence suggests that psychosomatic and nocebo-related adverse effects account for a significant proportion of common adverse effects following COVID-19 vaccination. The most common adverse effects are headache, fati
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Gouttebarge, Vincent, Haruhito Aoki, and Gino Kerkhoffs. "Symptoms of Common Mental Disorders and Adverse Health Behaviours in Male Professional Soccer Players." Journal of Human Kinetics 49, no. 1 (2015): 277–86. http://dx.doi.org/10.1515/hukin-2015-0130.

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Abstract To present time, scientific knowledge about symptoms of common mental disorders and adverse health behaviours among professional soccer players is lacking. Consequently, the aim of the study was to determine the prevalence of symptoms of common mental disorders (distress, anxiety/depression, sleep disturbance) and adverse health behaviours (adverse alcohol behaviour, smoking, adverse nutrition behaviour) among professional soccer players, and to explore their associations with potential stressors (severe injury, surgery, life events and career dissatisfaction). Cross-sectional analyse
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Pongpitpitak, Nitchamon, Nahathai Wongpakaran, Tinakon Wongpakaran, and Weerapong Nuansri. "Buffering Effect of Perseverance and Meditation on Depression among Medical Students Experiencing Negative Family Climate." Healthcare 10, no. 10 (2022): 1895. http://dx.doi.org/10.3390/healthcare10101895.

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Background and objective: Thirty percent of Thai medical students experienced depression. Two of the crucial factors related to depression involved borderline personality disorder symptoms and adverse family experiences, while positive strengths were documented to prevent depression. This study aimed to investigate the role of perseverance and meditation on depression; Methods: Two hundred and forty−three medical student participants completed the following measurements: the core symptom index (CSI−D) to measure depression, the family climate questionnaire to measure family experience, the per
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Tongsantia, Umakorn, Sunisa Chaiklieng, Pornnapa Suggaravetsiri, Sari Andajani, and Herman Autrup. "Factors Affecting Adverse Health Effects of Gasoline Station Workers." International Journal of Environmental Research and Public Health 18, no. 19 (2021): 10014. http://dx.doi.org/10.3390/ijerph181910014.

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This cross-sectional study examined the risk factors affecting adverse health effects from benzene exposure among gasoline station workers in Khon Kean province, Thailand. An interview questionnaire of adverse symptoms relating to benzene toxicity was administered to 151 workers. Area samplings for benzene concentration and spot urine for tt-muconic acid (tt-MA), a biomarker of benzene exposure, were collected. The factors associated with adverse symptoms were analysed by using multiple logistic regression. It was found that these symptoms mostly affected fuelling workers (77.5%), and the dete
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Boisgontier, Matthieu P., Dan Orsholits, Martina von Arx, et al. "Adverse Childhood Experiences, Depressive Symptoms, Functional Dependence, and Physical Activity: A Moderated Mediation Model." Journal of Physical Activity and Health 17, no. 8 (2020): 790–99. http://dx.doi.org/10.1123/jpah.2019-0133.

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Background: Adverse childhood experiences, depressive symptoms, and functional dependence are interrelated. However, the mechanisms underlying these associations remain unclear. The authors investigated the potential of depressive symptoms to mediate the effect of adverse childhood experiences on functional dependence in older age and whether physical activity moderated this mediation. Method: Data from 25,775 adults aged 62 (9) years from the Survey of Health Ageing and Retirement in Europe were used in adjusted linear mixed-effects models to test whether depressive symptoms mediated the asso
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Srisuriyachanchai, Warisara, Anthony R. Cox, and Narumol Jarernsiripornkul. "Patients’ Identification, Management and Prevention of Adverse Drug Reactions: A Cross-Sectional Survey of Patients with Severe Adverse Drug Reactions." Journal of Clinical Medicine 13, no. 14 (2024): 4165. http://dx.doi.org/10.3390/jcm13144165.

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Background: Few studies have been conducted on how patients identify, manage, and prevent severe adverse drug reactions (ADRs). This study aimed to explore the reasoning that patients use to identify symptoms of severe ADRs and the methods they employ to manage and prevent them. Methods: A cross-sectional survey using structured telephone interviews was administered to patients with a self-assessed severe ADR and to patients with serious skin ADRs from a hospital medical record database (in-patient and out-patient) from 1 September 2016 to 1 September 2019. Patients identified via the medical
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Kraft, Brage, Rune Jonassen, Alexandre Heeren, Catherine Harmer, Tore Stiles, and Nils Inge Landrø. "Attention Bias Modification in Remitted Depression Is Associated With Increased Interest and Leads to Reduced Adverse Impact of Anxiety Symptoms and Negative Cognition." Clinical Psychological Science 7, no. 3 (2019): 530–44. http://dx.doi.org/10.1177/2167702618822480.

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Using a computational network approach, we reanalyzed data from a randomized controlled trial of attention bias modification (ABM) tasks on residual depression symptoms. The main aim was to characterize the symptom-to-symptom changes following ABM. ABM was associated with improvements in interest, which was in turn associated with improvements in other depression symptoms. Although there were no changes in the global network strength following ABM, the comparison with symptom change in the ABM and control group suggests that ABM leads to a reduction of the association between anxiety, depresse
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Anderson, Susan P., Dylan M. Zylla, Deepa M. McGriff, and Tom J. Arneson. "Impact of Medical Cannabis on Patient-Reported Symptoms for Patients With Cancer Enrolled in Minnesota’s Medical Cannabis Program." Journal of Oncology Practice 15, no. 4 (2019): e338-e345. http://dx.doi.org/10.1200/jop.18.00562.

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PURPOSE: Minnesota’s medical cannabis program is unique, in that it routinely collects patient-reported scores on symptoms. This article focuses on changes in symptom severity reported by patients with cancer during their first 4 months of program participation. MATERIALS AND METHODS: Patients with cancer in Minnesota’s medical cannabis program reported symptoms (anxiety, lack of appetite, depression, disturbed sleep, fatigue, nausea, pain, and vomiting) at their worst over the last 24 hours before each medical cannabis purchase. Baseline scores on each of the eight symptoms were statistically
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Hutchings, K. R., B. K. Hutchings, B. Ratnakaran, and A. S. Kablinger. "Donepezil-induced psychosis: a cautionary report of a rare adverse reaction." European Psychiatry 66, S1 (2023): S357—S358. http://dx.doi.org/10.1192/j.eurpsy.2023.778.

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IntroductionDonepezil is an acetylcholinesterase inhibitor approved by the Food and Drug Administration for the treatment of dementia in Alzheimer’s disease. While it is not curative for Alzheimer’s disease, donepezil has been shown to improve symptoms and slow disease progression; however, cases of rare psychiatric adverse effects, including hallucinations, mania, and increased confusion, have been reported. This report presents a case of donepezil-induced psychosis, which quickly resolved following cessation of the offending medication.ObjectivesTo illustrate a unique case of donepezil-induc
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de Bock, Sanne, Walter Szweryn, Thijs Jansen, et al. "Characteristics and Clinical Management Strategy of Petrous Apex Cholesterol Granulomas." Cancers 15, no. 4 (2023): 1313. http://dx.doi.org/10.3390/cancers15041313.

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Purpose: To evaluate the clinical characteristics of petrous apex cholesterol granulomas (PACG) and assess outcomes after different treatment strategies. Method: A consecutive case series of 34 patients with a PACG. Main outcomes were PACG growth, symptoms, and the outcomes of different treatment strategies: wait-and-scan (WS) and surgical drainage. Results: Thirty-four patients were analyzed; mean follow-up time was 7.1 years. Twenty-one patients (61.7%) showed symptoms, mostly more than one. Most symptoms reported were cranial nerve palsy (58.8%) and headache (35.3%). Twenty-one patients (61
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Cox, Amanda L., and Scott H. Sicherer. "Classification of adverse food reactions." Journal of Food Allergy 2, no. 1 (2020): 3–6. http://dx.doi.org/10.2500/jfa.2020.2.200022.

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Foods can induce adverse reactions by a variety of mechanisms. An understanding of the characteristic signs and symptoms and the related mechanisms of adverse food reactions allows the clinician to efficiently diagnose and treat patients. Adverse reactions to foods can be classified based on whether there is a nonimmunologic or immunologic basis for symptoms. Food intolerance, or a nonimmunologic reaction, includes a range of responses to foods that result primarily from an individual’s intrinsic inability to metabolize a component of the food, e.g., lactose sugar in dairy products. Other noni
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