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1

King, B. F., and J. H. Szurszewski. "Peripheral reflex pathways involving abdominal viscera: transmission of impulses through prevertebral ganglia." American Journal of Physiology-Gastrointestinal and Liver Physiology 256, no. 3 (1989): G581—G588. http://dx.doi.org/10.1152/ajpgi.1989.256.3.g581.

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In neurophysiological terms, divergence describes the transmission of impulse traffic from a single afferent line, through an integrating nervous system, and out into multiple efferent lines. This feature has been ascribed to the vertebrate central nervous system and invertebrate ganglionic systems but has not yet been associated with the autonomic nervous system in mammals. Therefore, this study investigated the degree of divergence of afferent impulse traffic through a mammalian autonomic ganglion, the inferior mesenteric ganglion (IMG) in guinea pig. Multiunit discharges were recorded extra
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2

Ivanichev, G. A., N. G. Starosel'tseva, A. R. Gainutdinov, R. G. Esin, L. Zh Mindubaeva, and G. I. Safiullina. "Polysynaptic reflex complexes in clinical neurology." Kazan medical journal 81, no. 5 (2022): 372–78. http://dx.doi.org/10.17816/kazmj96274.

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The results of the study of spinobulbospinal reflex during 25 years in healthy people and in various nervous system diseases with affection of afferent and efferent systems, subcortical formations of brain and muscles (facial muscle contracture, miofascial pain syndrome) are given. It is shown that the inconstancy of many reflex characteristics (latency, amplitude, response duration, manifestation) is its basic property in normal conditions. In central nervous system pathology the stabilization of the m entioned parameters comes showing disorder of the program of formation and performance of m
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3

Fried, K., and M. Devor. "End-Structure of Afferent Axons Injured in the Peripheral and Central Nervous System." Somatosensory & Motor Research 6, no. 1 (1988): 79–99. http://dx.doi.org/10.3109/08990228809144642.

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4

Overton, J. M., G. Davis-Gorman, and L. A. Fisher. "Central nervous system cardiovascular actions of CRF in sinoaortic-denervated rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 258, no. 3 (1990): R596—R601. http://dx.doi.org/10.1152/ajpregu.1990.258.3.r596.

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Studies were performed in unrestrained conscious Sprague-Dawley rats to examine the central nervous system (CNS) mechanism by which corticotropin-releasing factor (CRF) produces simultaneous elevations of arterial pressure and heart rate. To test the hypothesis that CRF inhibits ongoing impulse transmission through and/or transmitter release from the CNS terminations of baroreceptor afferents, the cardiovascular effects of intracerebroventricular administration of CRF were compared in rats subjected to prior sham surgery (Sham) or sinoaortic denervation (SAD). Resting levels of arterial pressu
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5

Henke, Austin M., Zackery J. Billington, and David R. Gater. "Autonomic Dysfunction and Management after Spinal Cord Injury: A Narrative Review." Journal of Personalized Medicine 12, no. 7 (2022): 1110. http://dx.doi.org/10.3390/jpm12071110.

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The autonomic nervous system (ANS), composed of the sympathetic and parasympathetic nervous systems, acts to maintain homeostasis in the body through autonomic influences on the smooth muscle, cardiac muscles, blood vessels, glands and organs of the body. The parasympathetic nervous system interacts via the cranial and sacral segments of the central nervous system, and the sympathetic nervous system arises from the T1–L2 spinal cord segments. After a spinal cord injury (SCI), supraspinal influence on the ANS is disrupted, leading to sympathetic blunting and parasympathetic dominance resulting
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6

Trasia, Reqgi First, Samsul Mustofa, Endang Purwaningsih, and Sri Wahyu Herlinawati. "ASPEK NEUROSAINS DALAM PATOFISIOLOGI PRURITUS NOKTURNAL." EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan 1, no. 2 (2024): 64–77. http://dx.doi.org/10.62335/2cyt9p58.

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Itching at night in scabies patients is considered a very disturbing symptom. It is known that the main role of the itch sensation and subsequent motor response is to remove environmental influences from the skin, especially arthropods. The purpose of this article is to provide an understanding of the overall physiology and associated pathophysiology of itch. This article focuses on the neuronal aspect, as the nervous system is necessary to perceive the sensation of itch, as well as the multidirectional connections between the nervous and immune systems that influence the transmission of itch
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7

NEIMAN, ALEXANDER B., and DAVID F. RUSSELL. "STOCHASTIC DYNAMICS OF ELECTRORECEPTORS IN PADDLEFISH." Fluctuation and Noise Letters 04, no. 01 (2004): L139—L149. http://dx.doi.org/10.1142/s0219477504001744.

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Electroreceptors in paddlefish serve as accessible and well-defined biological models for studying the functional roles in sensory nervous systems of noisy oscillations and the nonlinear phenomena associated with them, including synchronization, noise-induced transitions, and noise-induced bursting. The spontaneous dynamics of paddlefish electroreceptors show two oscillatory modes: one associated with 26 Hz oscillations in the sensory epithelia, and another with 30-65 Hz periodicities of afferent terminals. This novel type of organization of peripheral sensory receptors, with two distinct type
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8

Reardon, Colin, Kaitlin Murray, and Alan E. Lomax. "Neuroimmune Communication in Health and Disease." Physiological Reviews 98, no. 4 (2018): 2287–316. http://dx.doi.org/10.1152/physrev.00035.2017.

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The immune and nervous systems are tightly integrated, with each system capable of influencing the other to respond to infectious or inflammatory perturbations of homeostasis. Recent studies demonstrating the ability of neural stimulation to significantly reduce the severity of immunopathology and consequently reduce mortality have led to a resurgence in the field of neuroimmunology. Highlighting the tight integration of the nervous and immune systems, afferent neurons can be activated by a diverse range of substances from bacterial-derived products to cytokines released by host cells. While a
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9

Cairns, B. E., J. Liu та H. Wong. "Expression of α1 adrenergic receptor subtypes by afferent fibers that innervate rat masseter muscle". Scandinavian Journal of Pain 16, № 1 (2017): 167. http://dx.doi.org/10.1016/j.sjpain.2017.04.010.

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Abstract Aims In temporomandibular disorders sufferers, muscle pain is more severe in individuals who have undergone a traumatic stress. Why stress exacerbates masticatory muscle pain in these individuals is not known. One possibility is that under conditions of stress there is an interaction between the sympathetic and sensory nervous systems. This study investigated whether trigeminal ganglion neurons that innervate the masseter muscle express α1 adrenergic receptor subtypes to identify whether a direct interaction between the sympathetic and sensory nervous systems is feasible. Methods Mass
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10

Chernjavsky, Alex, and John Moody. "Spontaneous Development of Modularity in Simple Cortical Models." Neural Computation 2, no. 3 (1990): 334–54. http://dx.doi.org/10.1162/neco.1990.2.3.334.

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The existence of modular structures in the organization of nervous systems (e.g., cortical columns, patches of neostriatum, and olfactory glomeruli) is well known. However, the detailed dynamic mechanisms by which such structures develop remain a mystery. We propose a mechanism for the formation of modular structures that utilizes a combination of intrinsic network dynamics and Hebbian learning. Specifically, we show that under certain conditions, layered networks can support spontaneous localized activity patterns, which we call collective excitations, even in the absence of localized or spat
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11

Papir-Kricheli, Dalia, and Marshall Devor. "Abnormal Impulse Discharge in Primary Afferent Axons Injured in the Peripheral versus the Central Nervous System." Somatosensory & Motor Research 6, no. 1 (1988): 63–77. http://dx.doi.org/10.3109/08990228809144641.

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12

Shimizu, Nobutaka, Tetsuichi Saito, Naoki Wada, et al. "Molecular Mechanisms of Neurogenic Lower Urinary Tract Dysfunction after Spinal Cord Injury." International Journal of Molecular Sciences 24, no. 9 (2023): 7885. http://dx.doi.org/10.3390/ijms24097885.

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This article provides a synopsis of current progress made in fundamental studies of lower urinary tract dysfunction (LUTD) after spinal cord injury (SCI) above the sacral level. Animal models of SCI allowed us to examine the effects of SCI on the micturition control and the underlying neurophysiological processes of SCI-induced LUTD. Urine storage and elimination are the two primary functions of the LUT, which are governed by complicated regulatory mechanisms in the central and peripheral nervous systems. These neural systems control the action of two functional units in the LUT: the urinary b
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13

Meier, Bettina A., Marion U. Goebel, Claudia Gierse, Michael S. Exton, and Manfred Schedlowski. "Klassische Konditionierung von Immunfunktionen: Mechanismen und klinische Relevanz." Zeitschrift für Medizinische Psychologie 11, no. 2 (2002): 83–93. https://doi.org/10.3233/zmp-2002-11_2_06.

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Die Klassische Konditionierung von Funktionen des Immunsystems belegt eindrucksvoll die wechselseitige Kommunikation zwischen dem Nervensystem, dem Hormonsystem und dem Immunsystem. Die vornehmlich tierexperimentellen Befunde zeigen, das humorale und zelluläre Immunfunktionen mit Hilfe des Konditionierungsparadigmas sowohl supprimiert als auch stimuliert werden können. Dabei scheinen insbesondere adrenerge und opioiderge Transmitter und Rezeptorsysteme die afferente und efferente Informationsvermittlung zwischen Nervensystem und Immunsystem im Rahmen der Konditionierung von immunologischen Fun
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14

Hudson, Arthur J. "Pain Perception and Response: Central Nervous System Mechanisms." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 27, no. 1 (2000): 2–16. http://dx.doi.org/10.1017/s0317167100051908.

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ABSTRACT:Although several decades of studies have detailed peripheral and ascending nociceptive pathways to the thalamus and cerebral cortex, pain is a symptom that has remained difficult to characterize anatomically and physiologically. Positron emission tomography (PET) and functional magnetic imaging (fMRI) have recently demonstrated a number of cerebral and brain stem loci responding to cutaneous noxious stimuli. However, intersubject variability, both in the frequency and increased or decreased intensity of the responses, has caused uncertainty as to their significance. Nevertheless, the
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15

Filatova, Ye G., and L. A. Kazantseva. "Contribution of nonspecific systems of the brain to the pathogenesis of thyroid diseases." Problems of Endocrinology 40, no. 6 (1994): 26–29. http://dx.doi.org/10.14341/probl12188.

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Ten patients with diffuse toxic goiter, 12 nd degree, ten ones with hypothyrosis of medium severity, and a group of healthy controls were examined. Manifest emotional, personality, and vegetative disorders were revealed in patients of both groups, as well as changes in the electrical activity of the brain and in status of the afferent systems of the brain, this being indicative of marked dysfunction of nonspecific cerebral systems in patients with thyroid diseases. Anxiety depressive emotional disorders and activation of the in-depth compartments of the membranous reticular complex were reveal
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16

He, Wei, Xiaoyu Wang, Hong Shi, et al. "Auricular Acupuncture and Vagal Regulation." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/786839.

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Auricular acupuncture has been utilized in the treatment of diseases for thousands of years. Dr. Paul Nogier firstly originated the concept of an inverted fetus map on the external ear. In the present study, the relationship between the auricular acupuncture and the vagal regulation has been reviewed. It has been shown that auricular acupuncture plays a role in vagal activity of autonomic functions of cardiovascular, respiratory, and gastrointestinal systems. Mechanism studies suggested that afferent projections from especially the auricular branch of the vagus nerve (ABVN) to the nucleus of t
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17

Henriksen, Jens H., Helmer Ring-Larsen, and Niels Juel Christensen. "Sympathetic Nervous Regulation in Patients with Cirrhosis: Pathogenesis of Fluid Retention and Formation of Ascites." Canadian Journal of Gastroenterology 5, no. 3 (1991): 103–11. http://dx.doi.org/10.1155/1991/245757.

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Increased circulating noradrenaline in patients with cirrhosis is due to enhanced sympathetic nervous activity and is not merely the result of decreased clearance of catecholamines. There is a direct relation between the level of arterial norndrenaline and severity of cirrhosis, increased portal pressure and fluid accumulation; patients with the hepatorenal syndrome exhibit the highest values of plasma noradrenaline. In patients with cirrhosis, the kidneys have been identified as an important source of noradrenaline ‘spillover’ into plasma, which indicates enhanced sympathetic nervous activity
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18

Martino, Bussa, Lucia M., Mascaro A., Cuffaro L., Bontà T., and Rinaldi S. "Pathophysiology of Complex Regional Pain Syndrome Type I: Update." International Journal of Anesthesiology & Research 3, no. 7 (2015): 141–46. https://doi.org/10.19070/2332-2780-1500035.

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Background: Complex regional pain syndrome type I (CRPS I), also known as reflex sympathetic dystrophy (RSD), develops as disabling painful disorder following a trauma or surgery to a limb. We provide a review based on the current literature concerning the epidemiology and pathophysiology of CRPS I. Possible pathophysiological mechanisms of CRPS I are inflammation, sy mpathetic-afferent coupling and cortical changes. Methods: A literature search was conducted using, as electronic bibliographic database, Medline from 1980 until today. Results: CRPS I is a multifactorial disorder
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19

Fildes, R. D., and J. L. Atkins. "Substance P decreases fluid absorption in the renal proximal tubule." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 272, no. 5 (1997): R1396—R1401. http://dx.doi.org/10.1152/ajpregu.1997.272.5.r1396.

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Substance P is a neuropeptide found principally in the central nervous system and peripheral afferent nerve fibers. It is widely distributed in the body, and its local release is thought to have important effects in the normal physiology and pathophysiology of several organ systems. Substance P releases histamine from mast cells and nitric oxide from endothelial cells. Systemic infusion of substance P causes a brisk natriuresis. Previously, proximal tubule transport in the kidney was measured in vivo during the infusion of substance P. Transport was inhibited. This could have been a direct act
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20

Lemajic-Komazec, Slobodanka, and Zoran Komazec. "Initial evaluation of vertigo." Medical review 59, no. 11-12 (2006): 585–90. http://dx.doi.org/10.2298/mpns0612585l.

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Dizziness is one of the most common reasons patients visit their physicians. Balance control depends on receiving afferent sensory information from several sensory systems: vestibular, optical and proprioceptive. Bioelectric signals, generated by body movements in the semicircular canals and in the otolithic apparatus, are transported via the vestibular nerve to the vestibular nucleus. All four vestibular nuclei, located bilaterally in medial longitudinal fasciculus, are linked with central nervous system structures. These central nervous system structures are involved in maintaining visual st
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21

Stepanov, A. V., A. B. Seleznev, D. B. Ponomarev, V. Ya Apchel, and A. S. Ovchinnikova. "Neuroimmunoendocrine support of general biological organism reactions to adverse external factors." Bulletin of the Russian Military Medical Academy 22, no. 4 (2020): 196–200. http://dx.doi.org/10.17816/brmma62828.

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This paper presents the summarized information on the mechanisms of neuroimmunoendocrine organism reaction to external adverse impacts (irrespective of their etymology), and on the key elements in these reactions development. It is found that adverse external factors are responsible for a change of an organisms functional state, involving neuroendocrinal and immune systems in the (stress) reaction formation. Neuroendocrinal and immune systems act like coordinators of the intersystemic and interorgan relations in the setting of both adaptive and pathological processes. The combination of feed-f
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22

Rusanova, Dina V., Oleg L. Lakhman, and Natalya V. Slivnitsyna. "Comprehensive assessment of the nervous system in patients with vibration disease associated with the combined effects of local and general vibration." Russian Journal of Occupational Health and Industrial Ecology 65, no. 3 (2025): 150–57. https://doi.org/10.31089/1026-9428-2025-65-3-150-157.

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Introduction. Under the influence of industrial vibration, disorders form in various body systems, including the central nervous system (CNS). It is advisable to detect changes in the structures of the nervous system by conducting electroneuromyography (ENMG) with testing of sensory and motor axons with F-wave registration, determination of somatosensory evoked potentials, peripheral transcranial magnetic stimulation. The study aims to provide a comprehensive assessment of the structures of the nervous system (peripheral nerves, spinal cord neurons, thalamic region, cortical representation) in
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23

Schwartz, Gary J. "Integrative capacity of the caudal brainstem in the control of food intake." Philosophical Transactions of the Royal Society B: Biological Sciences 361, no. 1471 (2006): 1275–80. http://dx.doi.org/10.1098/rstb.2006.1862.

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The caudal brainstem nucleus of the solitary tract (NTS) is the initial central nervous system (CNS) terminus for a variety of gastrointestinal mechanical, nutrient chemical and gut peptide signals that limit the amount of food consumed during a meal. It receives neuroanatomical projections from gut vagal and non-vagal visceral afferents that mediate the CNS representation of these meal-stimulated gut feedback signals, and is reciprocally connected to a range of hypothalamic and limbic system sites that play significant roles in the neural processing of meal-related stimuli and in determining
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24

Saidel, William M. "Coherence in nervous system design: the visual system of Pantodon buchholzi." Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 355, no. 1401 (2000): 1177–81. http://dx.doi.org/10.1098/rstb.2000.0662.

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One of the more unusual visual systems of the Actinopterygii is that of Pantodon buchholzi (Osteoglossomorpha: Osteoglossidae). Its adaptations associate neuroanatomy at different levels of the visual system with ecological and behavioural correlates and demonstrate that the visual system of this fish has adapted for simultaneous vision in air and water. The visual field is divided into three distinct areas: for viewing into the water column, into air, and for viewing the aquatic reflection from the underside of the water surface. Cone diameters in different retinal areas correlate with the di
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25

Brooks, V. L., and J. W. Osborn. "Hormonal-sympathetic interactions in long-term regulation of arterial pressure: an hypothesis." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 268, no. 6 (1995): R1343—R1358. http://dx.doi.org/10.1152/ajpregu.1995.268.6.r1343.

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The importance of the sympathetic nervous system in short-term regulation of arterial pressure is well accepted. However, the question of whether neural systems participate in long-term control of pressure has been debated for decades and remains unresolved. The principal argument against such a control system is that arterial baroreceptors adapt to sustained changes in arterial pressure. In addition, denervation of baroreceptors has minimal to no effect on basal levels of arterial pressure chronically. This argument assumes, however, that baroreceptors provide the primary chronic feedback sig
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26

Korneva, E. A. "Pathways of neuro-immune communication: past and present time, clinical application." Medical Immunology (Russia) 22, no. 3 (2020): 405–18. http://dx.doi.org/10.15789/1563-0625-pon-1974.

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Fundamental studies in neuroimmunophysiology are the keystone for development of new therapeutic approaches to the treatment of infectious, allergic, oncologic and autoimmune diseases. The achievements in this field allowed approving new treatment methods based on irritation of afferent and efferent fibers of autonomic nerves. That became possible due to numerous studies of pathways between the immune and nervous systems performed over last two decades. The milestones in the history of neuroimmune communication research are represented here. The immune system organs – bone marrow, thymus and s
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27

Uglev, E. I., O. O. Muravsky, and Yu B. Lisun. "HEART RATE VARIABILITY IN ANESTHESIOLOGICAL PRACTICE." PAIN, ANAESTHESIA & INTENSIVE CARE, no. 1(94) (March 31, 2021): 20–24. http://dx.doi.org/10.25284/2519-2078.1(94).2021.230609.

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Introduction. Patient safety in optimal working conditions of the surgeon is the main task of the anesthesiology service. Neurovegetative homeostasis is the goal of the anesthesiologist [9, 19, 20, 49]. Full-fledged examination, identification of clear contraindications, extended monitoring; ensure joint and effective work of the team. The depth of anesthesia depends on a significant number of exogenous and endogenous factors. Many methods are used to assess the function of the cardiovascular system, which contributes to the performance of safe anesthesia. Much depends on the effect of the dru
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28

Katayama, Yoichi, James D. Glisson, Donald P. Becker, and Ronald L. Hayes. "Concussive head injury producing suppression of sensory transmission within the lumbar spinal cord in cats." Journal of Neurosurgery 63, no. 1 (1985): 97–105. http://dx.doi.org/10.3171/jns.1985.63.1.0097.

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✓ This study examines the effects of concussive levels of a fluid-percussion head injury on sensory transmission within the lumbar spinal cord of the cat. Primary afferent depolarization (PAD) was suppressed for 2 to 5 minutes following injury, as assessed by dorsal root potentials and augmentation of antidromic dorsal root potentials, both evoked by stimulation of adjacent dorsal roots. Polysynaptic reflex discharges in ventral root potentials evoked by dorsal root stimulation were also profoundly suppressed during this same period, even when spontaneous and monosynaptic reflex discharges wer
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29

de Jonge, Wouter J. "The Gut’s Little Brain in Control of Intestinal Immunity." ISRN Gastroenterology 2013 (April 4, 2013): 1–17. http://dx.doi.org/10.1155/2013/630159.

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The gut immune system shares many mediators and receptors with the autonomic nervous system. Good examples thereof are the parasympathetic (vagal) and sympathetic neurotransmitters, for which many immune cell types in a gut context express receptors or enzymes required for their synthesis. For some of these the relevance for immune regulation has been recently defined. Earlier and more recent studies in neuroscience and immunology have indicated the anatomical and cellular basis for bidirectional interactions between the nervous and immune systems. Sympathetic immune modulation is well describ
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30

Shevchenko, Oksana I. "Modern ideas about the state of neurofunctional activity of the brain under the professional influence of physical and chemical factors." Russian Journal of Occupational Health and Industrial Ecology 64, no. 3 (2024): 172–81. http://dx.doi.org/10.31089/1026-9428-2024-64-3-172-181.

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The article provides an overview of modern scientific approaches to assessing the state of neurofunctional activity of the brain under the professional influence of physical and chemical factors is presented, carried out using bibliographic databases Scopus, MedLine, Web of Science, PubMed, The Cochrane Library, RSCI, Cyberleninka, Google Academy, Index Copernicus, SJR, Science Direct, Arxiv.Org. The work reflects the results of research by domestic and foreign scientists stating the fact of violations of neurobioelectric activity, cerebral hemodynamics, afferent conductive structures, cytokin
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Schmitt, Oliver, Christian Nitzsche, Peter Eipert, Vishnu Prathapan, Marc-Thorsten Hütt, and Claus Hilgetag. "Reaction-diffusion models in weighted and directed connectomes." PLOS Computational Biology 18, no. 10 (2022): e1010507. http://dx.doi.org/10.1371/journal.pcbi.1010507.

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Connectomes represent comprehensive descriptions of neural connections in a nervous system to better understand and model central brain function and peripheral processing of afferent and efferent neural signals. Connectomes can be considered as a distinctive and necessary structural component alongside glial, vascular, neurochemical, and metabolic networks of the nervous systems of higher organisms that are required for the control of body functions and interaction with the environment. They are carriers of functional epiphenomena such as planning behavior and cognition, which are based on the
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32

Shvalev, V. N. "The global impact of Kazan neurohistochemical school and its founder professor A.N. Mislavsky; cherishing the traditions in further studies." Kazan medical journal 94, no. 3 (2013): 424–29. http://dx.doi.org/10.17816/kmj2200.

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Kazan school of neurohistology has a 150 years history. It became famous while headed by Aleksandr Nikolaevich Mislavsky. Honoured scientist of Russian Federation, Professor A.N. Mislavsky headed the faculty of histology of Kazan Medical Institute since 1921 till 1958. Well-known physicians V.S. Zimnitsky and I.M. Oxman worked under A.N. Mislavsky’s supervision, studying innervation of respiratory, gastrointestinal, urinary and other organ systems. An utterly new data on afferent and efferent nerve elements ratios in digestive tract, including concept of type 1 and 2 Dogiel cells were internat
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33

Rabbitt, R. D. "Semicircular canal biomechanics in health and disease." Journal of Neurophysiology 121, no. 3 (2019): 732–55. http://dx.doi.org/10.1152/jn.00708.2018.

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The semicircular canals are responsible for sensing angular head motion in three-dimensional space and for providing neural inputs to the central nervous system (CNS) essential for agile mobility, stable vision, and autonomic control of the cardiovascular and other gravity-sensitive systems. Sensation relies on fluid mechanics within the labyrinth to selectively convert angular head acceleration into sensory hair bundle displacements in each of three inner ear sensory organs. Canal afferent neurons encode the direction and time course of head movements over a broad range of movement frequencie
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34

Fox, Kevin, Helen Wallace, and Stanislaw Glazewski. "Is there a thalamic component to experience–dependent cortical plasticity?" Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 357, no. 1428 (2002): 1709–15. http://dx.doi.org/10.1098/rstb.2002.1169.

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Sensory deprivation and injury to the peripheral nervous system both induce plasticity in the somatosensory system of adult animals, but in different places. While injury induces plasticity at several locations within the ascending somatosensory pathways, sensory deprivation appears only to affect the somatosensory cortex. Experiments have been performed to detect experience–dependent plasticity in thalamic receptive fields, thalamic domain sizes and convergence of thalamic receptive fields onto cortical cells. So far, plasticity has not been detected with sensory deprivation paradigms that ca
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35

Morozova, M. P., A. D. Kurenkova, and B. A. Umarova. "The Role of Mast Cell-Neuron Tandem in the Regulation of Cardiac Function in Cardiovascular Pathologies." Российский физиологический журнал им И М Сеченова 110, no. 3 (2024): 349–74. http://dx.doi.org/10.31857/s0869813924030031.

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This review is consisted of new data about participation of mast cells (MCs) in the regulation of cardiac function in the development of some cardiovascular pathologies. In norm the number of MCs in the heart is very small compared to their number in barrier tissues. They are responsible for homeostasis of cardiac tissue and ensuring the interaction of the organ with the nervous and endocrine systems throughout the life of the organism. Pathological processes in the heart are accompanied by the development of inflammation reaction. MCs fulfil a significant role in the all stages of inflammatio
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36

Zhang, Sujuan, Yi Liu, Shiying Li, Feng Ye, Robert D. Foreman, and Jiande D. Z. Chen. "Effects of electroacupuncture on stress-induced gastric dysrhythmia and mechanisms involving autonomic and central nervous systems in functional dyspepsia." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 319, no. 1 (2020): R106—R113. http://dx.doi.org/10.1152/ajpregu.00256.2019.

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Electroacupuncture (EA) is widely used as an effective method to treat stress-related disorders. However, its mechanisms remain largely unknown. The aim of this study was to investigate the effects and mechanisms of EA on gastric slow wave (GSW) dysrhythmia and c-Fos expression in the nucleus of the solitary tract (NTS) induced by stress in a rodent model of functional dyspepsia (FD). Rats in the neonatal stage were treated using intragastric iodoacetamide. Eight weeks later, the rats were implanted with electrodes in the stomach for the measurement of GSW and electrodes into accupoints ST36 f
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Slater, Cody, Yuxiang Liu, Evan Weiss, Kunpeng Yu, and Qi Wang. "The Neuromodulatory Role of the Noradrenergic and Cholinergic Systems and Their Interplay in Cognitive Functions: A Focused Review." Brain Sciences 12, no. 7 (2022): 890. http://dx.doi.org/10.3390/brainsci12070890.

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The noradrenergic and cholinergic modulation of functionally distinct regions of the brain has become one of the primary organizational principles behind understanding the contribution of each system to the diversity of neural computation in the central nervous system. Decades of work has shown that a diverse family of receptors, stratified across different brain regions, and circuit-specific afferent and efferent projections play a critical role in helping such widespread neuromodulatory systems obtain substantial heterogeneity in neural information processing. This review briefly discusses t
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Лахман, Oleg Lakhman, Катаманова, et al. "CHARACTERISTICS OF DISTURBANCES IN NEUROPHYSIOLOGICAL AND PSYCHO-EMOTIONAL STATUS OF PATIENTS WITH VIBRATION DISEASE IN THE POSTEXPOSURE PERIOD." Бюллетень Восточно-Сибирского научного центра Сибирского отделения Российской академии медицинских наук 1, no. 6 (2016): 98–102. http://dx.doi.org/10.12737/23770.

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The article presents the results of the studies of the central and peripheral nervous systems, psychoemotional status of patients with vibration disease associated with exposure to the local vibration in the post-exposure period. The stud-ies were performed in patients with vibration disease (n=18) who do not work in the contact with the local vibration at present. The mean age of the patients was 50.7±5.4years, the mean length of service in the contact with local vibration –17.9±2.8years, the mean post-exposure period – 5.2±2.2years. 30male persons having no contact with industrial hazard wer
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Reetz, Kathrin, Imis Dogan, Christian Hohenfeld, et al. "Nonataxia symptoms in Friedreich Ataxia." Neurology 91, no. 10 (2018): e917-e930. http://dx.doi.org/10.1212/wnl.0000000000006121.

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ObjectiveTo provide a systematic evaluation of the broad clinical variability in Friedreich ataxia (FRDA), a multisystem disorder presenting mainly with afferent ataxia but also a complex phenotype of nonataxia symptoms.MethodsFrom the large database of the European Friedreich’s Ataxia Consortium for Translational Studies, 650 patients with genetically confirmed FRDA were included. Detailed data of medical history documentation, questionnaires, and reports on clinical features were analyzed to provide in-depth description of the clinical profile and frequency rates of phenotypical features wit
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Persson, P. B., H. Ehmke, W. W. Kohler, and H. R. Kirchheim. "Identification of major slow blood pressure oscillations in conscious dogs." American Journal of Physiology-Heart and Circulatory Physiology 259, no. 4 (1990): H1050—H1055. http://dx.doi.org/10.1152/ajpheart.1990.259.4.h1050.

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All physiological feedback systems (e.g., in arterial pressure control) tend to oscillate in a characteristic manner. Mechanoreceptors can effectively buffer resulting fluctuations in arterial blood pressure. In this study arterial and cardiopulmonary receptors were interrupted in eight conscious foxhounds by sectioning the afferent pathways to the central nervous system. In response, three major peaks were detected in the blood pressure power spectrum: in addition to the well-known rhythms reflecting heart rate and respiration, very slow oscillating waves with a cycle length of 20 +/- 4 min a
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Melehin, A. I. "Remote psychological assistance for chronic visceral pain associated with irritable bowel syndrome." Russian Journal of Telemedicine and E-Health 8, no. 1 (2022): 58–68. http://dx.doi.org/10.29188/2712-9217-2022-8-1-58-68.

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Chronic visceral pain, which increases with stress, is a hallmark of functional gastrointestinal disorders, such as irritable bowel syndrome (IBS). Modern pharmacological interventions, diets for patients with chronic visceral pain are usually insufficient, and many of them are fraught with undesirable side effects and short remission. Modern protocols of cognitive behavioral therapy of the third wave, which are available in a remote format, show efficiency, cost-effectiveness in relieving chronic visceral pain caused by stress. The article describes the specifics of the third wave of CBT in r
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Gardiner, S. M., T. Bennett, and T. P. O'Neill. "Synthetic capsaicin reversibly impairs vasopressin-mediated blood pressure recovery." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 257, no. 6 (1989): R1429—R1435. http://dx.doi.org/10.1152/ajpregu.1989.257.6.r1429.

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The vasopressin-mediated recovery of arterial pressure observed in adult rats following pharmacological blockade of the sympathetic nervous and renin-angiotensin systems is reduced by neonatal capsaicin treatment. We now demonstrate a similar but reversible effect following treatment of adult Wistar or Sprague-Dawley rats with N-vanillylnonanamide (50 mg/kg sc). One day after treatment, Wistar, but typically not Sprague-Dawley, rats had lost weight and exhibited increased sensitivity to the anesthetic effects of methohexital sodium. In both strains, captopril treatment caused hypotension. Afte
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Kurganskiy, A. M. "Integration of functional systems theory, properties of the nervous system, and a triple-network model of the brain in understanding temperaments." Novye issledovania, no. 2(82) (2025): 122–31. https://doi.org/10.46742/2072-8840-2025-82-2-122-131.

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The study is devoted to the integrative approach that links temperament with the blocks of the functional systems theory. Three key behavioral blocks are identified that successively replace each other: Block 1: Attention/analysis (afferent synthesis); Block 2: Action (programming and control); Block 3: State of rest (after accepting the result and triggering the acceptor of the result of the action). Based on this, hypothetically temperament is considered as a manifestation of the features of the transition between these blocks in the process of the behavioral cycle. In this case, a melanchol
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Hooper, S. L., M. Moulins, and L. Nonnotte. "Sensory input induces long-lasting changes in the output of the lobster pyloric network." Journal of Neurophysiology 64, no. 5 (1990): 1555–73. http://dx.doi.org/10.1152/jn.1990.64.5.1555.

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1. A long-lasting restructuring of the pyloric neural network of the lobster stomatogastric nervous system (STS) by a multisynaptic sensory afferent is described. This restructuring can be obtained either by mechanical stimulation of the pyloric region of the stomach or by brief high-frequency electrical stimulation of a nerve that innervates this region, the lateral posterolateral nerve (lpln). Electron microscopy shows that this nerve contains several thousand very small fibers (approximately 0.3 microns diam), the activation of some subset of which is responsible for the effects of lpln sti
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Raja-Khan, Nazia, Elisabet Stener-Victorin, XiaoKe Wu, and Richard S. Legro. "The physiological basis of complementary and alternative medicines for polycystic ovary syndrome." American Journal of Physiology-Endocrinology and Metabolism 301, no. 1 (2011): E1—E10. http://dx.doi.org/10.1152/ajpendo.00667.2010.

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Polycystic ovary syndrome (PCOS) is a common endocrine disorder that is characterized by chronic hyperandrogenic anovulation leading to symptoms of hirsutism, acne, irregular menses, and infertility. Multiple metabolic and cardiovascular risk factors are associated with PCOS, including insulin resistance, obesity, type 2 diabetes, hypertension, inflammation, and subclinical atherosclerosis. However, current treatments for PCOS are only moderately effective at controlling symptoms and preventing complications. This article describes how the physiological effects of major complementary and alter
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Dobrodeeva, L. K., A. V. Samodova, V. P. Patrakeeva, S. N. Balashova, and M. Yu Strekalovskaya. "Increased Concentrations of Dopamine in the Blood and the State of the Immune System in Practically Healthy Residents of the Northern Territories." Fiziologiâ čeloveka 50, no. 5 (2024): 95–105. http://dx.doi.org/10.31857/s0131164624050107.

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The numerous effects of dopamine are predetermined by the fact that it, being a chemical precursor of noradrenaline, is secreted in nervous tissue, in the adrenal medulla, kidneys, intestines, and APUD cells (Apudocytes). The purpose of the work is to study the effectiveness of immune reactions at elevated concentrations of dopamine in the blood of practically healthy residents of the northern territories. The results of an immunological examination of 1064 practically healthy people aged 25-55 years living in the Arkhangelsk and Murmansk regions, as well as in the Nenets Autonomous Okrug, the
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Campos-Ríos, Ana, Lola Rueda-Ruzafa, Salvador Herrera-Pérez, Paula Rivas-Ramírez, and José Antonio Lamas. "Tetrodotoxin: A New Strategy to Treat Visceral Pain?" Toxins 13, no. 7 (2021): 496. http://dx.doi.org/10.3390/toxins13070496.

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Visceral pain is one of the most common symptoms associated with functional gastrointestinal (GI) disorders. Although the origin of these symptoms has not been clearly defined, the implication of both the central and peripheral nervous systems in visceral hypersensitivity is well established. The role of several pathways in visceral nociception has been explored, as well as the influence of specific receptors on afferent neurons, such as voltage-gated sodium channels (VGSCs). VGSCs initiate action potentials and dysfunction of these channels has recently been associated with painful GI conditi
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Brune, Anthony, and Daniel Gold. "Acute Visual Disorders—What Should the Neurologist Know?" Seminars in Neurology 39, no. 01 (2019): 053–60. http://dx.doi.org/10.1055/s-0038-1677007.

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AbstractNormal vision requires coordination of precisely controlled and coordinated eye movements and normal function of a large cortical and subcortical sensory network. Given the required precision of the system and wide anatomic distribution of the motor and sensory visual systems, vision can be disrupted by a variety of central and peripheral nervous system disorders. While many of these may be relatively benign or have no proven therapy, several may be isolated presentations or harbingers of more serious neurologic conditions. Both monocular and binocular vision losses may be isolated pre
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Roh, Young Hak. "Neuropathic Pain: How to Assess and Treat a Maladaptive Pain Response." Archives of Hand and Microsurgery 25, no. 3 (2020): 238–47. http://dx.doi.org/10.12790/ahm.20.0018.

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Neuropathic pain is associated with primary lesion or dysfunction of the peripheral and central nerve systems, affecting up to 10% of the general population. Although both nociceptive pain and neuropathic pain utilize the same nervous system pathways, physiologic differences exist in the pathologic mechanism, clinical presentation, and treatments. Ectopic activity in primary afferent fibers, excitatory and inhibitory somatosensory signaling, nociceptive neuron alterations, and central pain modulation have been implicated in neuropathic pain. These neuropathic mechanisms are associated with the
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Travagli, R. Alberto, Gerlinda E. Hermann, Kirsteen N. Browning, and Richard C. Rogers. "III. Activity-dependent plasticity in vago-vagal reflexes controlling the stomach." American Journal of Physiology-Gastrointestinal and Liver Physiology 284, no. 2 (2003): G180—G187. http://dx.doi.org/10.1152/ajpgi.00413.2002.

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Vago-vagal reflex circuits modulate digestive functions from the oral cavity to the transverse colon. Previous articles in this series have described events at the level of the sensory receptors encoding the peripheral stimuli, the transmission of information in the afferent vagus, and the conversion of this data within the dorsal vagal complex (DVC) to impulses in the preganglionic efferents. The control by vagal efferents of the postganglionic neurons impinging on the glands and smooth muscles of the target organs has also been illustrated. Here we focus on some of the mechanisms by which th
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