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Dissertations / Theses on the topic 'African Trypanosomiases'

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Published: 4 June 2021

Last updated: 1 February 2022

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1

Kashiwazaki, Yoshihito. "A new immunodiagnosis for African trypanosomiases." Thesis, University of Liverpool, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359033.

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2

Rossi, B. C. "Macrophage function in African trypanosomiasis." Thesis, Brunel University, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.373784.

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3

Milligan, Paul. "Population dynamics of African trypanosomiasis." Thesis, University of Salford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306017.

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4

Bailey, Wendi. "The diagnosis of human African trypanosomiasis." Thesis, University of Liverpool, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260319.

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5

Hublart-Sinsoillier, Marylène. "Hypogonadisme et trypanosomiase africaine." Lille 1, 1989. http://www.theses.fr/1989LIL10127.

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Parmi les éléments cliniques et biologiques caractérisant la maladie du sommeil, l'apparition d'un hypogonadisme représente un élément de grande fréquence. Notre possibilité de réaliser des explorations, par des dosages radioimmunologiques des hormones sexuelles sur un nombre significatif de malades infectes par trypanosoma brucei gambiense, a permis de mesurer l'importance du dysfonctionnement endocrinien. Par des explorations dynamiques de l'axe gonadotrope, une origine supra ou extra hypophysaire à l'hypogonadisme peut être évoquée. L'adaptation sur le modèle animal, nous a permis d'explore

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6

Kroubi, Maya. "Développement de formulations colloïdales antiparasitaires pour traiter la trypanosomiase africaine." Thesis, Lille 2, 2010. http://www.theses.fr/2010LIL2S043/document.

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Cette thèse porte sur le développement d’une formulation colloïdale de diminazène (DMZ) à l’aide de nanoparticules polysaccharidiques cationiques (NP+) pour le traitement de la Trypanosomiase Africaine (TA).Nous avons étudié dans un premier temps le procédé de chargement des NP+ en DMZ base. Nous avons constaté que l’ajout de phospholipides dans la matrice des NP+ est nécessaire à l’association de DMZ. La quantité de phospholipide est d’ailleurs le facteur limitant de l’indice de saturation des NP+ en DMZ. Afin de ne pas dégrader le principe actif, lors de son chargement, le procédé choisi est

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7

Hoste, Christian. "Elevage et trypanosomiase animale africaine." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37605971k.

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8

Matemba, Lucas E. "Epidemiology of human African trypanosomiasis in western Tanzania." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/24915.

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This thesis started by reviewing the existing sleeping sickness historical records in Tanzania with the aim of exploring the evidence for the existence of <i>Trypanosoma brucei gambiense </i>in Tanzania. Findings from the available historical data did not provide sufficient evidence for the existence of <i>T. b. gambiense </i>sleeping sickness in Tanzania.<br> The thesis further estimated under-reporting of <i>T. b. rhodesiense </i>in endemic areas of Tanzania using an established model. Using data from a 2000-2004 outbreak of <i>T. b. rhodesiense </i>in Urambo, the model predicts 46% underrep

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9

Felu, Cécile. "Characterisation of the mechanism of human serum resistance in T.b.gambiense." Doctoral thesis, Universite Libre de Bruxelles, 2006. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210844.

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The two human pathogenic sub-species T.b.gambiense and T.b.rhodesiense can be distinguished from the morphologically identical T.b.brucei by their ability to infect humans, enabling them to cause sleeping sickness. This is because they are resistant to lysis by the lytic factor (APOL-I) present in normal human serum (NHS). In T.b.rhodesiense resistance to this lytic factor is due to a truncated VSG gene termed SRA which blocks lysis by interacting with APOL-I in the lysosome. SRA does not exist in T.b.gambiense. The search for a similar truncated VSG gene lead to the identification of a T.b.ga

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10

au, ngiles@anhb uwa edu, and Natalie Giles. "Exploitation of the Protein Tubulin For Controlling African Trypanosomiasis." Murdoch University, 2005. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20060315.191003.

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This thesis presents the results of an investigation into the structural protein, tubulin, as a potential target for anti-trypanosomatid drug discovery and vaccine development. Recombinant alpha- and beta- tubulin proteins from Trypanosoma brucei rhodesiense were expressed as soluble fusion proteins in an E. coli expression system. The recombinant alpha- and beta- tubulins were used to determine the nature of binding of novel trifluralin analogues EPL-AJ 1003, 1007, 1008, 1016 and 1017. Native tubulin from rats was used to determine the extent of binding to mammalian tubulin. The results of th

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11

Giles, Natalie. "Exploitation of the protein tubulin for controlling African trypanosomiasis." Giles, Natalie (2005) Exploitation of the protein tubulin for controlling African trypanosomiasis. PhD thesis, Murdoch University, 2005. http://researchrepository.murdoch.edu.au/40/.

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This thesis presents the results of an investigation into the structural protein, tubulin, as a potential target for anti-trypanosomatid drug discovery and vaccine development. Recombinant alpha- and beta- tubulin proteins from Trypanosoma brucei rhodesiense were expressed as soluble fusion proteins in an E. coli expression system. The recombinant alpha- and beta- tubulins were used to determine the nature of binding of novel trifluralin analogues EPL-AJ 1003, 1007, 1008, 1016 and 1017. Native tubulin from rats was used to determine the extent of binding to mammalian tubulin. The results of th

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12

Eltayeb, Ragaa Abdelkhalig. "Immunopathology and signalling molecules involved during experimental African trypanosomiasis /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4382-6/.

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13

Giles, Natalie Lydia. "Exploitation of the protein tubulin for controlling African trypanosomiasis /." Access via Murdoch University Digital Theses Project, 2005. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20060315.191003.

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14

Acup, Christine Amongi. "Epidemiology and control of human African trypanosomiasis in Uganda." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/16246.

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Poverty and disease are bound together in rural communities of sub-Saharan Africa (SSA) exacerbated by weak social services and conflict. The infectious disease burden in SSA combines the neglected tropical diseases (NTDs) and the 'big three' (malaria, HIV/AIDS and tuberculosis), so-called because they attract more global attention and hence funding. NTDs include human African trypanosomiasis (HAT or sleeping sickness), first noticed by the outside world during the slave trade era and later in the 2-th century by widespread epidemics of disease across the tsetse fly belt. HAT describes two dis

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15

Cecchi, Giuliano. "Biogeographical patterns of African trypanosomoses for improved planning and implementation of field interventions." Doctoral thesis, Universite Libre de Bruxelles, 2011. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209787.

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Spatially-explicit information is essential for planning and implementing interventions against vector-borne diseases. This is also true for African trypanosomoses, a group of diseases of both humans and animals caused by protozoa of the Genus Trypanosoma, and transmitted by tsetse flies (Genus Glossina).<p>In this thesis the knowledge gaps and the requirements for an evidence-based decision making in the field of tsetse and trypanosomoses are identified, with a focus on georeferenced data and Geographic Information Systems (GIS). Datasets, tools and analyses are presented that aim to fill som

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16

Kaushik, Radhey Shyam. "Macrophage cytokines as correlate of differential resistance to African trypanosomiasis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0014/NQ37893.pdf.

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17

Gould, Matthew K. "Putative phosphodiesterase inhibitors as potential new chemotherapies against African Trypanosomiasis." Thesis, University of Glasgow, 2009. http://theses.gla.ac.uk/1410/.

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African trypanosomiasis is a disease caused by the Kinetoplastida parasites Trypanosoma brucei rhodesiense and T. b. gambiense. The distribution of the disease is split geographically with T. b. rhodesiense found in eastern sub-Saharan Africa and T. b. gambiense in the west of the continent. Current treatment for this fatal disease is wholly unsatisfactory with problems such as extreme toxicity, affordability and the emergence of resistance. The case for the generation of new potential chemotherapies is compelling and urgent. Phosphodiesterase (PDE) enzymes degrade the secondary signalling mol

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18

Giordani, Federica. "New approaches to fluorescence-based diagnostics for human African trypanosomiasis." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2454/.

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In the absence of any vaccine, prophylactic drug and effective vector control, the fight against human African trypanosomiais (HAT) is based on the the combination of active case-finding and consequent drug treatment of identified positive cases. Unfortunately, low sensitivity and specificity of current diagnostic techniques often result in misdiagnosis, leaving infected patients without cure or exposing them to inappropriate chemotherapy protocols, which use dangerous and expensive drugs. The development of more efficient, simple, cheap and field-robust diagnostic tests is, therefore, urgentl

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19

Gichuki, Charity Wangui. "The role of astrocytes in the neuropathogenesis of African trypanosomiasis." Thesis, University of Glasgow, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294595.

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20

Sullivan, Lauren. "Discovery and development of diagnostic biomarkers for human African trypanosomiasis." Thesis, University of Dundee, 2012. https://discovery.dundee.ac.uk/en/studentTheses/e6c3197a-849b-4148-8326-58a2b13f5072.

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Human African Trypanosomiasis (HAT) or African Sleeping Sickness is a disease prevalent in many parts of Sub-Saharan Africa. HAT is a parasitic infection caused by two species, <em>Trypanosoma brucei gambiense</em> and <em>T. b. rhodesiense</em>. Clinical diagnosis is not sufficient as symptoms from other endemic diseases, such as Malaria, are similar. Currently the diagnosis of <em>T. b. gambiense</em> infection mainly relies on the Card Agglutination Test for Trypanosomiasis (CATT), which has severe limitations. Other diagnostic tests for <em>T. b. gambiense</em> and <em>T. b. rhodesiense</e

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21

Park, Suh Yeong. "Modeling Tsetse Fly Host Preference and African Trypanosomiasis in Cameroon." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1306862287.

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22

Mabbott, Neil A. "Nitric oxide : host-protective or host-destructive during African trypanosomiasis." Thesis, University of Aberdeen, 1995. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU543723.

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The aims of the research presented in this thesis were concerned with investigating the effect of inducible nitric oxide (NO) synthase expression during Trypanosoma brucei infections on both host and parasite. NO was shown to exhibit a potent cytostatic effect on parasite proliferation. Oxyhaemoglobin is a potent scavenger of NO. The cytostatic effects of NO on the trypanosomes were completely prevented through the addition of erythrocytes to the cultures. This implies that in the host blood-stream, NO is unlikely to be involved in the eradication of the parasites. Through the adoptive transfe

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23

Pedron, Julien. "Synthèse et étude de l'activité anti-kinétoplastidés de nouvelles 8-nitroquinoléin-2(1H))-ones bioactivées par les nitroréductases de type 1." Thesis, Toulouse 3, 2018. http://www.theses.fr/2018TOU30190/document.

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Les kinétoplastidés sont des protozoaires flagellés responsables de maladies tropicales négligées mortelles telles que la leishmaniose viscérale (L. donovani et L. infantum) ou la trypanosomiase humaine africaine (T. brucei), pour lesquelles les traitements disponibles sont très limités. Depuis quelques années, on observe un regain d'intérêt pour le développement de nitrohétérocycles aromatiques anti-infectieux tels que le delamanide et le féxinidazole. De récentes études indiquent que l'activité anti-kinétoplastidés de ces dérivés repose sur leur bioactivation sélective par des nitroréductase

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24

Stebeck, Caroline Elizabeth. "The identification and characterization of two unique membrane-associated molecules of African trypanosomes." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1996. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq21950.pdf.

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25

Ammar, Zeinab. "Caractérisation de l' interaction entre les trypanosomes africains et les cellules endothéliales : activation, inflammation et rôle des trans-sialidases." Thesis, Bordeaux 2, 2013. http://www.theses.fr/2013BOR22057/document.

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La trypanosomose est la maladie parasitaire la plus dévastatrice en Afrique, et affecte à la fois les hommes et le bétail. Vu l’inefficacité des stratégies de contrôle actuelles, une stratégie alternative dite “anti-maladie” a été proposée dans le cadre de la trypanosomose animale. Elle vise à neutraliser les effets de la maladie plutôt qu’à éliminer le parasite. Une telle stratégie nécessite une meilleure compréhension du développement de la pathologie ainsi qu’une caractérisation détaillée des facteurs de virulence impliqués. Dans ce contexte, nous nous sommes intéressés à l’étude de l’inter

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26

Hamadien, Maha. "Parasite signalling and host responses in experimental and human African trypanosomiasis /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-266-3.

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27

Ebiloma, Godwin Unekwuojo. "Identification of new lead compounds for the treatment of African trypanosomiasis." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8340/.

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28

Akiode, Olukemi Adejoke. "Examination and management of human African Trypanosomiasis propagation using geospatial techniques." Thesis, Abertay University, 2014. https://rke.abertay.ac.uk/en/studentTheses/9419b401-6604-4530-9938-57ab03234e67.

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Human African Trypanosomiasis (HAT) is a vector-borne disease transmitted by the bite of the tsetse fly that results in high human morbidity and mortality. The propagation of the disease has been linked to environmental factors, and understanding the vector’s habitat is vital to its control. There is no HAT vaccine, but biological control of the vector has been successful in reducing HAT incidence. However, in recent years the disease has re-emerged and spread. Due to insufficient knowledge of HAT endemic foci, the disease management remains challenging. To achieve effective deployment of cont

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29

Jones, Amy. "Melarsoprol cyclodextrin inclusion complexes for the treatment of human African trypanosomiasis." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2713/.

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Human African trypanosomiasis (HAT) is a parasitic disease caused by the protozoan parasites T. b. rhodesiense and T. b. gambiense. The disease is currently endemic in 36 sub-Saharan countries with an estimated 60 million people at risk from the infection. The disease progresses through two stages; an early or haemolymphatic stage where the parasites are confined to the peripheral compartment and a late or encephalitic stage where the parasites penetrate the blood-brain barrier (BBB) and invade the CNS. Without treatment the disease is invariably fatal but at present chemotherapy is reliant on

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30

Liu, Yajuan. "A role of sympathetic nervous system in immunomodulation of early experimental African trypanosomiasis /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-113-X/.

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31

Jacquot, Laurence. "Les traitements de la trypanosomose africaine humaine : les données actuelles de la thérapeutique." Paris 5, 1990. http://www.theses.fr/1990PA05P124.

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32

Whitecavage, Kellie Ann. "The characterization of a novel and essential trypanosome protein." Click here for download, 2008. http://proquest.umi.com/pqdweb?did=1490081941&sid=1&Fmt=2&clientId=3260&RQT=309&VName=PQD.

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33

Barrett, John Charles. "Economic issues in trypanosomiasis control : case studies from Southern Africa." Thesis, University of Reading, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385554.

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34

Silva, Achani Madushika. "Energetic basis of inappetence in an experimental murine infection of African Trypanosomiasis." Thesis, University of Aberdeen, 2015. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=230060.

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Trypanosoma brucei is the vector of African trypanosomiasis in both domestic animals (nagana) and sleeping sickness in humans (Human African Trypanosomiasis). These protozoan parasites are transmitted by the bite of infected tsetse flies (Glossina sp.). African trypanosome infections cause parasite-induced anorexia (PIA) and cachexia in livestock, experimental animals and in humans, and are of economic, veterinary and medical importance in sub-Saharan Africa. The overall aim of this project was to characterise the phenomenon of inappetence in relation to overall energy budget in African trypan

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35

Sharafeldin, Ahmed. "Immunological studies in the brain and signaling pathways in experimental African trypanosomiasis /." Stockholm : [Karolinska institutets bibl.], 2001. http://diss.kib.ki.se/2001/91-7349-072-5/.

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36

Cox, Andrew Paul. "Epidemiological analysis of host populations with widespread sub-patent infections : African trypanosomiasis." Thesis, University of Edinburgh, 2007. http://hdl.handle.net/1842/1560.

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The epidemiological study of pathogens largely depends on three technologies, serology, microscopy and the polymerase chain reaction (PCR). Serological methods are unable to differentiate between current and past infections. Microscopy has historically been the mainstay of epidemiological study. In recent times the use of microscopy has been in decline, as it has been shown to have an inherent lack of sensitivity and specificity and produces many false negative results. PCR is now the method of choice for screening samples for the presence or absence of pathogens. Although PCR is widely regard

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37

Checci, Francesca. "Gambiense human African trypanosomiasis transmission dynamics and the impact of disease detection." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.536845.

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38

Palmer, Jennifer Jacqueline. "Utilisation of human African trypanosomiasis passive screening services in post-conflict Sudan." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.557286.

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39

Baker, Nicola Louise. "Screening for new natural drugs and drug resistance determinants in African trypanosomiasis." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590629.

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40

Force-Barge, Pierre. "La trypanosomiase humaine au Congo en 1990." Montpellier 1, 1991. http://www.theses.fr/1991MON11075.

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41

Ayed, Zoulikha. "Trypanosome humaine africaine : détection d'autoanticorps anti-neurofilaments et anti-tubulines : essai d'immunisation contre la trypanosomose expérimentale." Limoges, 1999. http://www.theses.fr/1999LIMO117G.

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La Trypanosomose Humaine Africaine (THA)à T. B. Gambiense est caractérisée par une atteinte du système nerveux central (phase II) dont la pathogénie, encore indéterminée, pourrait relever de phénomènes auto-immuns. L'étude du répertoire immunitaire de patients atteints de THA en phase lymphatico-sanguine (phase I) et en phase II, nous a permis de mettre en évidence dans le sérum et dans le LCR de ces patients la présence conjointe d'autoanticorps dirigés contre deux protéines du cytosquelette cellulaire. Il s'agit d'anticorps dirigés contre des protéines de filaments intermédiaires spécifiques

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Ngo, Nonga Sylvie. "Une nouvelle thérapeutique de la trypanosomose africaine humaine : l'éflornithine." Paris 5, 1993. http://www.theses.fr/1993PA05P053.

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43

Lane-Serff, Harriet. "Structural insights into innate immunity against African trypanosomes." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:3a1415e6-3df4-42dd-827b-d05edb2137be.

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The haptoglobin-haemoglobin receptor (HpHbR) is expressed by the African try- panosome, T. brucei, whilst in the bloodstream of the mammalian host. This allows ac- quisition of haem, but also results in uptake of trypanolytic factor 1, a mediator of in- nate immunity against non-human African trypanosomes. Here, the structure of HpHbR in complex with its ligand, haptoglobin-haemoglobin (HpHb), is presented, revealing an elongated binding site along the membrane-distal half of the receptor. A ~50° kink allows the simultaneous binding of two receptors to one dimeric HpHb, increasing the effi

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Nalunkuma, Kazibwe Anne J. "Factors influencing the spread and selection of drug resistance in Human African Trypanosomiasis." Thesis, University of Glasgow, 2008. http://theses.gla.ac.uk/381/.

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A growing problem with drug resistance in Human African Trypanosomiasis has necessitated the implementation of screening programmes to monitor for its spread. This thesis describes the study of several factors that can influence the selection and propagation of drug resistance in T. brucei. Human African Trypanosomiasis (HAT) is caused by T. brucei gambiense and T. brucei rhodesiense. The few drugs used for the treatment of the disease are either toxic, cause severe side effects or suffer from parasite resistance. The T. brucei P2 transporter, which is encoded by the gene TbAT1, mediates uptak

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45

O'Doherty, Oran Gilliland. "Synthesis of novel trypanosome alternative oxidase inhibitors for the treatment of African trypanosomiasis." Thesis, University of Sussex, 2016. http://sro.sussex.ac.uk/id/eprint/64718/.

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African trypanosomiasis is a protozoan infection affecting tens of thousands of people and millions of livestock animals across sub-Saharan Africa. In humans the disease is fatal without chemotherapeutic intervention and in animals it causes a severe anaemia that greatly impairs productivity. Available drug compounds are difficult to administer and unacceptably toxic. A natural product, ascofuranone, inhibits a key trypanosome specific respiratory enzyme, trypanosome alternative oxidase, and was shown over a decade ago to be trypanocidal using both in vitro and in vivo experiments. The compoun

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46

Steketee, Pieter Christiaan. "Investigating the mode of action of AN5568, a novel therapeutic against African trypanosomiasis." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7478/.

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The protozoan parasite Trypanosoma brucei is the causative agent of Human African Trypanosomiasis (HAT) and Nagana disease in mammals. These diseases present a major socioeconomic burden to large areas of sub-Saharan Africa. Current therapeutics involve complex and toxic regimens which can lead to fatal side-effects. In addition, there is evidence for drug resistance emerging in the field. Hence, there is a desperate need for novel therapies. Benzoxaboroles are a novel class of boron-containing compounds under development for use against a wide spectrum of diseases. AN5568 is a lead compound f

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47

TEMPORÃO, Adriana Beatriz Oliveira. "Different models of DNA immunization as strategy for vaccine development against African Trypanosomiasis." Master's thesis, Instituto de Higiene e Medicina Tropical, 2016. http://hdl.handle.net/10362/19048.

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A tripanosomose Africana, também conhecida como Doença do Sono, causada pelo protozoário Trypanosoma brucei, é uma doença tropical negligenciada. Esta doença pode ser controlada, tal como foi provado no passado; no entanto, o crescente número de pessoas afectadas e em risco torna o desenvolvimento de uma vacina uma prioridade. T. brucei é capaz de evadir constantemente o sistema imunitário do hospedeiro, devido ao seu extraordinário mecanismo de defesa, que lhe proporciona uma grande variação antigénica. Devido a este mecanismo de defesa tem sido muito difícil de desenvolver uma vacina eficaz

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48

Hickey, Meghan C. "Exploring an unusual beta-hydroxybutyrate dehydrogenase from Trypanosoma brucei." Click here for download, 2010. http://proquest.umi.com.ps2.villanova.edu/pqdweb?did=2011158651&sid=1&Fmt=7&clientId=3260&RQT=309&VName=PQD.

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49

Jamnadass, Harmanjeet Ramni. "Identification and characterisation of an extrachromosomal element from a multidrug-resistant isolate of Trypanosoma brucei brucei." Thesis, Brunel University, 1995. http://bura.brunel.ac.uk/handle/2438/4314.

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Drug resistance together with difficulties involved in the development of new trypanocides are a major problem in the present control of African trypanosomiasis. DNA based diagnostics for drug resistance would overcome problems in the identification of drug-resistant populations and contribute to effective control measures. However, this requires a detailed knowledge of the mode of action and the mechanisms by which trypanosomes can overcome the toxic effects of trypanocides. In this study, a search for molecular differences between a multidrug-resistant isolate of Trypanosoma brucei brucei, C

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Amevigbe, Dotse Dzabli Martin. "Les anticorps anti-cérébrosides au cours de la trypanosomose humaine africaine et expérimentale du mouton (ovis aries)." Limoges, 1992. http://www.theses.fr/1992LIMOA101.

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