Relevant bibliographies by topics / Age dependence of neurogenesis after stroke

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Academic literature on the topic 'Age dependence of neurogenesis after stroke'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Age dependence of neurogenesis after stroke"

1

Adamczak, Joanna, Markus Aswendt, Christina Kreutzer, et al. "Neurogenesis upregulation on the healthy hemisphere after stroke enhances compensation for age-dependent decrease of basal neurogenesis." Neurobiology of Disease 99 (December 20, 2016): 47–57. https://doi.org/10.1016/j.nbd.2016.12.015.

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Abstract Stroke is a leading cause of death and disability worldwide with no treatment for the chronic phase available. Interestingly, an endogenous repair program comprising inflammation and neurogenesis is known to modulate stroke outcome. Several studies have shown that neurogenesis decreases with age but the therapeutic importance of endogenous neurogenesis for recovery from cerebral diseases has been indicated as its ablation leads to stroke aggravation and worsened outcome. A detailed characterization of the neurogenic response after stroke related to ageing would help to develop novel a
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2

Pintana, Hiranya, Grazyna Lietzau, Ingrid Lovise Augestad, et al. "Obesity-induced type 2 diabetes impairs neurological recovery after stroke in correlation with decreased neurogenesis and persistent atrophy of parvalbumin-positive interneurons." Clinical Science 133, no. 13 (2019): 1367–86. http://dx.doi.org/10.1042/cs20190180.

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Abstract Type 2 diabetes (T2D) hampers stroke recovery though largely undetermined mechanisms. Few preclinical studies have investigated the effect of genetic/toxin-induced diabetes on long-term stroke recovery. However, the effects of obesity-induced T2D are mostly unknown. We aimed to investigate whether obesity-induced T2D worsens long-term stroke recovery through the impairment of brain’s self-repair mechanisms – stroke-induced neurogenesis and parvalbumin (PV)+ interneurons-mediated neuroplasticity. To mimic obesity-induced T2D in the middle-age, C57bl/6j mice were fed 12 months with high
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3

Kathner-Schaffert, Carolin, Lina Karapetow, Madlen Günther, et al. "Early Stroke Induces Long-Term Impairment of Adult Neurogenesis Accompanied by Hippocampal-Mediated Cognitive Decline." Cells 8, no. 12 (2019): 1654. http://dx.doi.org/10.3390/cells8121654.

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Stroke increases neurogenesis in the adult dentate gyrus in the short term, however, long-term effects at the cellular and functional level are poorly understood. Here we evaluated the impact of an early stroke lesion on neurogenesis and cognitive function of the aging brain. We hypothesized that a stroke disturbs dentate neurogenesis during aging correlate with impaired flexible learning. To address this issue a stroke was induced in 3-month-old C57Bl/6 mice by a middle cerebral artery occlusion (MCAO). To verify long-term changes of adult neurogenesis the thymidine analogue BrdU (5-Bromo-2′-
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4

Adamczak, Joanna, Markus Aswendt, Christina Kreutzer, et al. "Neurogenesis upregulation on the healthy hemisphere after stroke enhances compensation for age-dependent decrease of basal neurogenesis." Neurobiology of Disease 99 (March 2017): 47–57. http://dx.doi.org/10.1016/j.nbd.2016.12.015.

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5

Мякотных, В. С., Е. С. Остапчук, and О. М. Хромцова. "SEXUAL ACTIVITY: DEPENDENCE ON AGE, GENDER, VARIOUS CARDIOVASCULAR DISEASES AND CEREBRAL STROKE." Успехи геронтологии, no. 3 (August 2, 2021): 384–95. http://dx.doi.org/10.34922/ae.2021.34.3.007.

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Целью представленного исследования явилось определение места и роли сексуальных расстройств у представителей разного пола и возраста в развитии фоновой для церебрального инсульта патологии и формировании клинической картины острого периода инсульта и его последствий. Детально рассматривали вопросы интимной жизни 111 пациентов (58 мужчин и 53 женщины) в предшествовавшие инсульту периоды и определяли возможные связи с клиническими особенностями острого периода инсульта. У 77 из этих 111 пациентов изучали динамику сексуальных нарушений в связи с особенностями функционального дефекта, сформировавш
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6

Lieschke, Simone, Bozena Zechmeister, Matteo Haupt, et al. "CCL11 Differentially Affects Post-Stroke Brain Injury and Neuroregeneration in Mice Depending on Age." Cells 9, no. 1 (2019): 66. http://dx.doi.org/10.3390/cells9010066.

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CCL11 has recently been shown to differentially affect cell survival under various pathological conditions including stroke. Indeed, CCL11 promotes neuroregeneration in neonatal stroke mice. The impact of CCL11 on the adult ischemic brain, however, remains elusive. We therefore studied the effect of ectopic CCL11 on both adolescent (six-week) and adult (six-month) C57BL6 mice exposed to stroke. Intraperitoneal application of CCL11 significantly aggravated acute brain injury in adult mice but not in adolescent mice. Likewise, post-stroke neurological recovery after four weeks was significantly
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7

Joundi, Raed A., Gustavo Saposnik, Rosemary Martino, Jiming Fang, and Moira K. Kapral. "Development and Validation of a Prognostic Tool for Direct Enteral Tube Insertion After Acute Stroke." Stroke 51, no. 6 (2020): 1720–26. http://dx.doi.org/10.1161/strokeaha.120.028949.

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Background and Purpose— We aimed to create a novel prognostic risk score to estimate outcomes after direct enteral tube placement in acute stroke. Methods— We used the Ontario Stroke Registry and linked databases to obtain clinical information on all patients with direct enteral tube insertion after ischemic stroke or intracerebral hemorrhage from July 1, 2003 to June 30, 2010 (derivation cohort) and July 1, 2010 to March 31, 2013 (validation cohort). We used multivariable regression to assign scores to predictor variables for 3 outcomes after tube placement: favorable outcome (discharge modif
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8

Baubekov, A. A., T. K. Tajibayev, Ye M. Miyerbekov, et al. "S100B PROTEIN CONTENT IN ISCHEMIC STROKE AND ITS PROGNOSTIC VALUE IN PATIENTS SUBJECTED TO INVASIVE INTERVENTIONS." BULLETIN OF SURGERY IN KAZAKHSTAN, no. 3 (October 1, 2023): 23–28. http://dx.doi.org/10.35805/bsk2023iii004.

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The aim of the study is to determine the levels of the S100B protein in patients with ischemic stroke and evaluate its relationship with the size of brain tissue damage, stroke severity, and clinical outcomes. Materials and methods.The study included 113 patients with acute ischemic stroke, hospitalized within the first day after its onset and subjected to invasive treatment. 101 men and 12 women were examined, including 32 at the age of 50-60, 64 at the age of 61-70, 17 at the age of 71-80. parameters and degree of functional deviations according to the NIHSS scale. Results. The content of S1
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9

Broomfield, Niall, Matthew Walters, and Robert M. West. "Carer strain in post-stroke emotionalism: a cross-sectional analysis." BMJ Open 14, no. 12 (2024): e084079. https://doi.org/10.1136/bmjopen-2024-084079.

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ObjectivesPost-stroke emotionalism (PSE) is a common, under-researched neurologic symptom of stroke, characterised by frequent crying episodes not under usual social control. Currently, there are no data on carer strain in the context of emotionalism after stroke. We aimed to explore the degree of carer strain in carers of individuals with diagnosed PSE compared with carers of individuals with stroke but no PSE to examine whether carer strain varies with particular characteristics of the cared for individual (patient age, sex, social deprivation, stroke type, functional status, mood status) an
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10

Yamaguchi, Susumu, Nobutaka Horie, Katsuya Satoh, et al. "Age of donor of human mesenchymal stem cells affects structural and functional recovery after cell therapy following ischaemic stroke." Journal of Cerebral Blood Flow & Metabolism 38, no. 7 (2017): 1199–212. http://dx.doi.org/10.1177/0271678x17731964.

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Cell transplantation therapy offers great potential to improve impairments after stroke. However, the importance of donor age on therapeutic efficacy is unclear. We investigated the regenerative capacity of transplanted cells focusing on donor age (young vs. old) for ischaemic stroke. The quantities of human mesenchymal stem cell (hMSC) secreted brain-derived neurotrophic factor in vitro and of monocyte chemotactic protein-1 at day 7 in vivo were both significantly higher for young hMSC compared with old hMSC. Male Sprague-Dawley rats subjected to transient middle cerebral artery occlusion tha
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Books on the topic "Age dependence of neurogenesis after stroke"

1

Leys, Didier, Charlotte Cordonnier, and Valeria Caso. Stroke. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0067.

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Stroke is a major public health issue. Many are treatable in the acute stage, provided patients are admitted soon enough. The overall incidence of stroke in Western countries is approximately 2400 per year per million inhabitants, and 80% are due to cerebral ischaemia. The prevalence is approximately 12 000 per million inhabitants. Stroke is associated with increased long-term mortality, handicap, cognitive and behavioural impairments, recurrence, and an increased risk of other types of vascular events. It is of major interest to take the heterogeneity of stroke into account, because of differ
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Leys, Didier, Charlotte Cordonnier, and Valeria Caso. Stroke. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0067_update_001.

Full text
Abstract:
Stroke is a major public health issue. Many are treatable in the acute stage, provided patients are admitted soon enough. The overall incidence of stroke in Western countries is approximately 2400 per year per million inhabitants, and 80% are due to cerebral ischaemia. The prevalence is approximately 12 000 per million inhabitants. Stroke is associated with increased long-term mortality, handicap, cognitive and behavioural impairments, recurrence, and an increased risk of other types of vascular events. It is of major interest to take the heterogeneity of stroke into account, because of differ
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3

Leys, Didier, Charlotte Cordonnier, and Valeria Caso. Stroke. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0067_update_002.

Full text
Abstract:
Stroke is a major public health issue. Many are treatable in the acute stage, provided patients are admitted soon enough. The overall incidence of stroke in Western countries is approximately 2400 per year per million inhabitants, and 80% are due to cerebral ischaemia. The prevalence is approximately 12 000 per million inhabitants. Stroke is associated with increased long-term mortality, handicap, cognitive and behavioural impairments, recurrence, and an increased risk of other types of vascular events. It is of major interest to take the heterogeneity of stroke into account, because of differ
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