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Dissertations / Theses on the topic 'Ageing'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Abdullah, Syed Zaki. "Membrane ageing due to chemical cleaning agent." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/46862.

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Sodium hypochlorite is commonly used as a cleaning agent to remove adsorbed foulants from PVDF-based micro/ultra filtration membranes in water and wastewater treatment applications. Although effective for fouling control, extended sodium hypochlorite exposure can affect the physical/chemical characteristics and hinder the treatment performance of these membranes. In the present study, experiments were conducted to comprehensively quantify the effects of sodium hypochlorite exposure on changes in the physical/chemical characteristics and the filtration performances of blended PVDF-based support

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2

Hall, Nicola. "Modulation of ageing characteristics with an anti-ageing compound." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:4cc41454-5b9f-41e9-b7fc-62f33b05cf15.

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Investigating the cellular processes anti-ageing compounds interact with can identify genes and pathways involved in ageing. The macrolide lactone FK506 was identified in a phenotypic screen as extending lifespan in yeast and C. elegans through an unknown mechanism. FK506 also ameliorates neurodegeneration and age-related weight gain in rodents. Here, the mechanism of action of FK506 has been investigated in two experimental systems: C. elegans and 3T3-L1 mouse adipocytes. As the general mechanisms of ageing are well conserved between C. elegans and mammals, C. elegans has been used to underst

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3

Richardson, Cassandra. "Awareness in ageing." Thesis, University of Southampton, 2008. https://eprints.soton.ac.uk/66450/.

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Deficits in awareness are found in diseases of ageing, and with acute and traumatic brain injury. Despite investigations of awareness in ageing patient populations, little is known about any potential effects of normal ageing on awareness. The Hierarchies of Processing model (Stuss, Picton & Alexander, 2001) provided a theoretical framework for an investigation of different types of awareness in healthy ageing. Four empirical studies are reported in this thesis. An investigation of sensory processing using ERP components found that older adults had reduced attentional capture of auditory stimu

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4

Maaskant, Marianne Adriana. "Mental handicap and ageing." Dwingeloo : Maastricht : KAVANAH ; University Library, Maastricht University [Host], 1993. http://arno.unimaas.nl/show.cgi?fid=6582.

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5

Deans, Karen. "Ageing of Saccharomyces cerevisiae." Thesis, Heriot-Watt University, 1997. http://hdl.handle.net/10399/663.

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6

Pennington, Elisabeth Anne. "Temporal memory in ageing." Thesis, University of Warwick, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247969.

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7

Newman, Tracey Anne. "Ageing and Alzheimer's disease." Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246220.

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8

Harvey, Jessica. "Ageing and health literacy." Thesis, Canterbury Christ Church University, 2018. http://create.canterbury.ac.uk/17653/.

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Background: Older people are more likely to have poorer health literacy skills, experience more health problems and worse health outcomes compared to younger people. Aims: The aim of the study was to explore whether age differences between older people’s and younger people’s performance on a health literacy task would reduce with multimodal health information, presented by video, compared with unimodal information presented by audio and text on its own. Method: 24 older adults and 25 younger adults completed a test predictive of intelligence and an experimental task where they were shown infor

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9

Brümmer, Laura. "Ageing and emotion regulation." Thesis, University of Southampton, 2009. https://eprints.soton.ac.uk/153301/.

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The thesis commences with a review of trends in declining psychological disorders as a person ages. These findings are understood in terms of differences between older and younger adults’ emotion processing. Socio-emotional selectivity theory is introduced as one account of these age differences. Literature is reviewed which illustrates how certain emotion regulation strategies are utilised differently in older and younger adults. The consequences of these emotion regulation strategies on affect, cognition and mental and physical health are illustrated. Inconsistencies and gaps in the literatu

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10

Enegela, Odagboyi. "Ageing of overhead conductors." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/ageing-of-overhead-conductors(77eb04ae-7a95-4443-bc62-ba0de2664590).html.

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Overhead conductors used in the transmission of power in grids around the world are generally subjected to ageing, which is the time-based change of their properties. Important properties such as corona discharge, audible noise, hydrophobicity and corrosion are usually considered and investigated. On some conductors such as the aluminium conductor steel reinforced (ACSR), a reduction in audible noise over exposure time to the service environment has been noted to occur. However, the converse has been observed for the gap-type thermal resistant aluminium conductor steel reinforced (GTACSR or “M

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11

Megale, Rodrigo Zunzarren. "Musculoskeletal pain and ageing." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/19884.

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Musculoskeletal pain is a complex phenomenon involving biomechanics, inflammation and central pain processing pathways. The ageing process and ageing-related conditions can affect the course of musculoskeletal pain; conversely, the presence of pain can affect the ageing process, contributing to increased risks of adverse health outcomes. Despite the importance of managing pain in older adults, questions remain in terms of the best approach as the use of analgesics in this population is associated with increased risks of adverse events. This thesis contributes to the current knowledge of how ag

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12

ARIGONI, LUIZA BECK. "DESIGN AND AGEING: GUIDING CONCEPTS FOR THE ACTIVITY OF DESIGN TOWARDS HEALTHY AGEING." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2017. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=33798@1.

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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO<br>CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO<br>Com o aumento da longevidade populacional, é natural que diversas áreas do saber e da atuação humana estejam voltando suas atenções ao envelhecimento, em abordagens múltiplas e mesmo antagônicas. Nesse cenário, o objetivo deste trabalho é apontar possíveis caminhos para a atividade do design em um mundo em envelhecimento. Porque o design é uma atividade interdisciplinar e seu processo se dá em parceria de campos distintos da atuação humana, o primeiro passo foi investigar o qu

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13

Mason, Janet. "The biology of ageing : pro- and anti-ageing signals from the reproductive system." Thesis, University of East Anglia, 2013. https://ueaeprints.uea.ac.uk/47949/.

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This context of this thesis is that ageing is characterised by the accumulation of random cellular damage leading to a decrease in reproductive function and survival, which ends in death. The antagonistic pleiotropy theory for ageing suggests selection favours genes with positive effects on early life even if detrimental effects are observed in later life, indicating a trade-off between lifespan and reproductive output. Ageing, however, is a complex genetic trait and strong interactions between genes that influence longevity and environment including with diet, stress and pharmacological facto

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14

Pg, Hj Mohd Yassin D. K. Hayati Bte. "Novel template ageing techniques to minimise the effect of ageing in biometric systems." Thesis, University of Kent, 2016. https://kar.kent.ac.uk/58398/.

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Effect of ageing on biometric systems and particularly its impact on face recognition systems. Being biological tissue in nature, facial biometric trait undergoes ageing. As a result developing biometric applications for long-term use becomes a particularly challenging task. Despite the rising attention on facial ageing, longitudinal study of face recognition remains an understudied problem in comparison to facial variations due to pose, illumination and expression changes. Regardless of any adopted representation, biometric patterns are always affected by the change in the face appearance due

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15

LA, ROCCA STEFANIA. "THE IMPORTANCE OF BEING OLDEST: AGEISM AND MEMORY IN THE AGEING SOCIETY." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2021. http://hdl.handle.net/10281/325877.

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Dal 2002, anno in cui l’Organizzazione mondiale della Sanità ha sancito i principi per promuovere politiche economiche e di welfare orientate all’Active Ageing, anche la letteratura in campo psicologico operante nel settore dell’invecchiamento si è mossa in accordo con questi principi. La tesi di dottorato presenta degli studi inerenti l’invecchiamento che vertono su due tematiche principali: da un lato i fattori psicosociali nell’invecchiamento intesi come atteggiamento e percezione della propria età; dall’altro i processi cognitivi maggiormente colpiti nell’invecchiamento sano, in particolar

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16

Alfaqawi, Rami Mohammed S. "Investigation into ageing and the effect of hydrated lime on mastics and mixture ageing." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/52304/.

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Age hardening of bitumen is one of the key factors determining the lifetime of an asphalt pavement. When the bitumen is excessively aged, the asphalt mixture will become brittle and its ability of supporting traffic-induced stresses and strains may significantly reduce, which can easily cause some cracking damage to the bound layer of a pavement. As bitumen is always in contact with mineral fillers in asphalt mixtures, the mechanisms of oxidative ageing of binders are significantly influenced by the physical and chemical interaction between fillers and the bitumen. For a long while, attempts t

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17

Camacho, Barcia María Lucía. "Vitamin K & healthy ageing." Doctoral thesis, Universitat Rovira i Virgili, 2020. http://hdl.handle.net/10803/670246.

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La transició demogràfica cap a una societat més envellida ha esdevingut un desafiament per l’economia social global, especialment pels sistemes de salut públics. Per tal de millorar la qualitat de vida fins un procés d’envelliment més saludable, son necessàries evidències que suportin diferents promotors de salut en condicions relacionades amb l’edat. Prèviament, s’ha suggerit que la vitamina K podria desenvolupar un paper modulador en el procés de l’envelliment i els mecanismes relacionats amb l’edat, com l’estrès oxidatiu, la inflamació i la resistència a la insulina. No obstant, l’evidència

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18

McLaughlin, Deirdre P. "Ageing and epilepsy : psychosocial impact /." [St. Lucia, Qld.], 2005. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe19068.pdf.

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19

Meyer, Christine. "Planning for an Ageing Population." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-89298.

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The majority of local areas in the UK are faced with an ageing population. Popular retirement destinations in coastal and more rural areas are particularly affected. The thesis aims to find out how local areas strategically tackle these demographic shifts. The British government has issued strategic guidance for local areas, but as yet little is known about how actual responses look. The literature has largely focused on good practice compilations. Consequently, the thesis attempts to analyse in depth local areas’ experiences in planning for an ageing population. The main research question is:

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20

Cook, Joanna Clare. "Ageing and inhibition in memory." Thesis, University of Southampton, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288442.

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21

Crowley, Christopher Keith Aerospace Civil &amp Mechanical Engineering Australian Defence Force Academy UNSW. "Meeting the ageing aircraft challenge." Awarded by:University of New South Wales - Australian Defence Force Academy. School of Aerospace, Civil and Mechanical Engineering, 2004. http://handle.unsw.edu.au/1959.4/38679.

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&quotMeeting the ageing aircraft challenge&quot is not just about safety, not just about effectiveness, and not just about economy of support. It is about proactive and reactive optimization of all three service goals throughout long life cycles that span 20 or 30 years, or more, and typically, beyond the originally intended design life. It is therefore about organizational attitudes towards ongoing trend analysis and condition monitoring, and pervading cost benefit assessments of all forms of human innovation across what the author describes as 'the eight sustaining disciplines for long aero

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22

Crisi, Giovanna M. "Autoimmunity and effect of ageing." [Maastricht : Maastricht : Universiteit Maastricht] ; University Library, Maastricht University [Host], 1999. http://arno.unimaas.nl/show.cgi?fid=8571.

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23

Johansson, Lars S. "Bitumen ageing and hydrated lime /." Stockholm, 1998. http://www.lib.kth.se/abs98/joha0528.pdf.

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24

Riley, M. Louise. "Alcohol, aldehydes, ageing and cataract." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260233.

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25

Papakonstantinou, Lida. "Physical activity, exercise and ageing." Thesis, University of Newcastle Upon Tyne, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556012.

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Ageing refers to a multidimensional process of physical, psychological, and social change of an organism over time. As life expectancy increases the prevalence of ageing related diseases raises. Thus, it becomes essential to distinguish the contributions to health and disease of ageing per se and lifestyle. It is well established that increased physical activity can protect against metabolic diseases and reduce mortality. However, methods of inducing a durable increase in daily physical activity are not well established and there are particular difficulties in bringing about long term changes

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26

Garner, Philippa Elizabeth. "Bone ageing and structural disconnection." Thesis, University of Leeds, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590273.

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Bone is dynamic and adaptable. It has been suggested that each region has an intrinsic hypothetical 'mechanostat' (Frost, 1987), although the histological basis has yet to be clearly defined. To gain further insight, the phenomenon of connection and disconnection is explored within the calcifying protist Spirostomum ambiguum, and at three key structural hierarchical tissue levels of the human skeleton; the cancellous bone network, the osteocyte network and the periosteal Sharpey's fibre arrays. The tissue used was from elderly subjects; cadaveric vertebral bodies, and femoral heads after hip r

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27

Hughes, Catherine Frances. "B-vitamins and healthy ageing." Thesis, University of Ulster, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551554.

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B-vitamin deficiency may contribute to age-related diseases. Low/deficient vitamin B 12 status is of particular concern in older people despite the fact that intakes of B 12 typically far exceed current recommendations. Pernicious anaemia accounts for a very small proportion of low/deficient status, however, a much more prevalent problem is food-bound vitamin B 12 malabsorption. Proton pump inhibitor [PPI] drugs are acid suppressant drugs which reduce gastric acid secretion [hypochlorhydria] and could thus potentially reduce the absorption of food-bound vitamin B 12. Using an experimental mode

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28

Allen, George. "Modelling the evolution of ageing." Thesis, University of York, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516608.

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29

Elliot, Trevor. "Geochemical indicators of groundwater ageing." Thesis, University of Bath, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278513.

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30

McAuley, Mark Thomas. "Systems modelling of human ageing." Thesis, University of Newcastle Upon Tyne, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437936.

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31

Mankouri, Hocine William. "DNA helicases and yeast ageing." Thesis, University of Liverpool, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367550.

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32

Hoffman, Elizabeth. "Epigenetics and genetics of ageing." Thesis, University of Southampton, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396775.

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33

Lawrie, Louisa. "Adult ageing and emotion perception." Thesis, University of Aberdeen, 2018. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=239235.

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Older adults are worse than young adults at perceiving emotions in others. However, it is unclear why these age-related differences in emotion perception exist. The studies presented in this thesis investigated the cognitive, emotional and motivational factors influencing age differences in emotion perception. Study 1 revealed no age differences in mood congruence effects: sad faces were rated as more sad when participants experienced negative mood. In contrast, Study 2 demonstrated that sad mood impaired recognition accuracy for sad faces. Together, findings suggested that different methods o

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34

McNulty, Clare. "Ageing, inflammation and cardiovascular function." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6541/.

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Age is associated with the development of multi-system function loss including the musculoskeletal, immune and cardiovascular system, as well as body composition changes. These age-related alterations lead to frailty development and disease progression, reducing quality of life. A major lifestyle change occurring in later years is reduced physical activity levels. This thesis sought to examine the associations between physical activity and multi-system function loss in a cohort of elderly individuals, and to better understand the neural mechanisms underpinning the circulatory responses to exer

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35

Phillipson, Kate. "Ageing and crystallisation of polycaprolactone." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6540/.

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Partially crystalline polycaprolactone stored at different temperatures well above the glass transition temperature is found to age with the development of further crystallinity and an increase in melting point, yield stress and elastic modulus with time. The changes in mechanical properties are accounted for by the increased crystallinity, and the increase in melting point to an increase in lamellae thickness. Over the temperature range studied, the rate of ageing increase with temperature and the dependence of stem length on the square root of storage time observed are both consistent with d

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36

Blaudin, de Thé Francois-Xavier. "Engrailed, an anti-ageing homeoprotein." Thesis, Paris 6, 2015. http://www.theses.fr/2015PA066204/document.

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Les homéoprotéines sont des facteurs de transcription morphogénétiques qui ont des fonctions cellulaire et non cellulaire-autonomes. Par exemple, En1 et En2 (Engrailed/En) sont importants pour le développement des neurones dopaminergiques du mésencéphale (mDA) et cruciaux pour leur maintien chez l'adulte. Les souris En1+/- présentent une dégénération progressive et spécifique des neurones mDA de la Substantia Nigra pars compacta (SNpc), rappelant la maladie de Parkinson. De plus, l'infusion d'En dans plusieurs modèles de la maladie sauve ces neurones. Dans le modèle MPTP, cela passe par l'augm

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37

Davis, Luke M. "Predictive modelling of bone ageing." Thesis, University of East Anglia, 2013. https://ueaeprints.uea.ac.uk/45085/.

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Bone age assessment (BAA) is a task performed daily by paediatricians in hospitalsworldwide. The main reasons for BAA to be performed are: fi�rstly, diagnosis of growth disorders through monitoring skeletal development; secondly, prediction of final adult height; and fi�nally, verifi�cation of age claims. Manually predicting bone age from radiographs is a di�fficult and time consuming task. This thesis investigates bone age assessment and why automating the process will help. A review of previous automated bone age assessment systems is undertaken and we investigate why none of these systems h

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38

Khojah, Sohair Mohammed. "Ageing in the mammalian brain." Thesis, University of Glasgow, 2015. http://theses.gla.ac.uk/6244/.

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With a globally ageing population diseases associated with this natural process are becoming major issues worldwide. Research into the process of ageing and its concomitant issues is rapidly expanding; the need for new tools and models to investigate this rapidly expanding arena of research is paramount. The discovery of a spontaneous mutation in the AS rat strain which introduces a premature stop mutation into the gene encoding protein kinase C γ (PKCγ) lead to the development of a model for one such age related disorder, Parkinson's disease. Consequently, this model has been selected to inve

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39

Harris, Mathew Alan. "Navigational strategy switching in ageing." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/10066.

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With advancing age, many cognitive faculties deteriorate, and navigation abilities may be among those most affected. The majority of previous work investigating navigation impairments in ageing has focused on allocentric processing, attributing deficits to hippocampal dysfunction. However, real-world navigation is dependent upon numerous different strategies, as well as the ability to flexibly switch between them. Outside the context of navigation, it has been demonstrated that strategy switching, thought to be coordinated by regions of prefrontal cortex and the locus coeruleus-noradrenergic s

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40

Pearman, Charles. "Arrhythmogenesis in the ageing atria." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/arrhythmogenesis-in-the-ageing-atria(9bfce19e-4d3d-4139-8a7d-7a8c72589ffa).html.

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Atrial Fibrillation (AF) is rare amongst young people whilst epidemic in the elderly. Whilst much is known about the pathophysiology of AF, the mechanisms underlying the vulnerability to AF amongst older people in incompletely understood. Young (< 18 months, first quintile of life) and old (> 8 years, last quintile of life) Welsh mountain sheep were used to investigate changes in atrial electrophysiology with age. Old sheep were more vulnerable to induced AF than young sheep. On the surface ECG, p-wave duration increased with age suggesting increasing atrial size. The corrected sinus node reco

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41

Pereira, Andreia Sofia Boanova Vieira. "Population ageing and monetary policy." Master's thesis, Instituto Superior de Economia e Gestão, 2016. http://hdl.handle.net/10400.5/11996.

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Mestrado em Economia Monetária e Financeira<br>O envelhecimento da população altera a dinâmica das principais variáveis macroeconómicas com implicações para a condução da política monetária e estabilidade dos preços. O presente trabalho pretende analisar as principais tendências demográficas e de que forma influenciam o ambiente económico onde a política monetária é conduzida, causando direta ou indiretamente movimentos indesejados nas taxas de inflação. Recorrendo a uma técnica polinomial, estimamos a relação empírica entre a estrutura etária e a inflação para um painel de 24 países da OCDE d

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42

Mok, Robert. "Working memory in healthy ageing." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:36594546-962e-4f81-ad91-589dcd96f029.

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This thesis is concerned with the age-related changes in working memory (WM), and the inter-individual differences in cognitive and neural mechanisms that correspond to healthy versus poor ageing of WM function. The first half of this thesis focusses on the age-related decline in WM and whether preserved top-down attentional control could mitigate such deficits. In Chapter 2, I present a functional MRI study showing that older adults reliably recruit brain networks that subserve cognitive control, which work in concert with the task relevant sensory areas during effective selective WM. In Chap

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43

Yu, Xiong. "Ageing mechanisms in composite insulators." Thesis, University of Manchester, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685301.

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This thesis presents investigations of field-aged composite silicone rubber insulators, which have been deployed for 15 years on a 400 k V transmission line in a coastal region of the UK. Extensive measurements of their hydrophobicity, as detennined by contact angle, are given along with a description of their appearance. The hydrophobicity change varies from the low voltage end to the high voltage end with the lowest contact angles being found in the middle of the string. The sheds also aged differently around their circumference and this was reflected in discoloration differences on differen

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44

Ertas, Hasan. "Ageing of silica in HPLC." Thesis, Loughborough University, 1998. https://dspace.lboro.ac.uk/2134/33118.

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This study may be divided into two sections which cover different aspects of the reproducibility problems encountered in HPLC. In the first, the study has involved the separation of basic drugs, on different manufacturer's reversed-phase columns in conjunction with an acid buffered acetonitrile/water gradient. The retention reproducibility of each drug was assessed and compared on the basis of the retention index scale of 1-nitroalkanes. The effect of changing gradient run time on the reproducibility of the retention values of the 1-nitroalkanes was demonstrated on reversed-phases of different

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45

Mills, David H. "Electroluminescence and ageing of polyethylene." Thesis, University of Southampton, 2012. https://eprints.soton.ac.uk/338950/.

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Electrical insulation is known to age when under electrical stress. One cause of this is thought to relate to the movement and build up of charge within the insulation. The emission of a low level of light from polymeric materials when under electrical stressing is shown to occur before the onset of currently detectable material degradation. This light is termed electroluminescence (EL)and under an ac electric field is thought to relate to the interaction of charge in close proximity to the electrode-polymer interface. Understanding the cause of this light emission gives a very high resolution

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46

Dao, Ngoc Long. "Impulse ageing of polymeric materials." Thesis, University of Southampton, 2011. https://eprints.soton.ac.uk/201099/.

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Impulse over-voltage is a common phenomenon in electric power systems. A switching impulse is created by a switching surge or local fault while a lightning impulse is due to direct lightning strike to high voltage plant such as an overhead line. Both impulse events create travelling waves in the system, damaging insulation components and equipment. This work is concerned with the hypothesis that lightning impulses can lead to accelerated ageing of extruded polymeric cables. The results show that there may well be a reduction in electric field strength of the insulation of a power cable that ex

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47

Meyer, Christine. "Planning for an Ageing Population." Doctoral thesis, Leibniz-Institut für ökologische Raumentwicklung e.V, 2011. https://tud.qucosa.de/id/qucosa%3A26060.

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The majority of local areas in the UK are faced with an ageing population. Popular retirement destinations in coastal and more rural areas are particularly affected. The thesis aims to find out how local areas strategically tackle these demographic shifts. The British government has issued strategic guidance for local areas, but as yet little is known about how actual responses look. The literature has largely focused on good practice compilations. Consequently, the thesis attempts to analyse in depth local areas’ experiences in planning for an ageing population. The main research question is:

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48

Sung, Chang Hoon. "Coping with ageing in Korea." Paris, Institut d'études politiques, 2003. http://www.theses.fr/2003IEPP0022.

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Burns, David. "Ageing in the zebrafish heart." Thesis, University of Newcastle upon Tyne, 2014. http://hdl.handle.net/10443/2705.

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Abstract:

With advancing age there is a progressive decline in the function of the heart. In humans reductions in stroke volume and cardiac output occurs often resulting in cardiac disease and subsequent death. The pathology found in the heart due to advancing age is attributed to a reduction in cardiomyocytes which causes cardiac dysfunction and heart disease, leading to heart failure. Zebrafish are a valuable tool in studying ageing and heart disease. As zebrafish age they gradually senesce. This is similar to humans and other mammals. However the response of the zebrafish heart to ageing has not been

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50

Pararasa, Chathyan. "Fatty acids, monocytes and ageing." Thesis, Aston University, 2013. http://publications.aston.ac.uk/20894/.

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Abstract:

Elevated free fatty acids (FFA) are a feature of ageing and a risk factor for metabolic disorders such as cardiovascular disease (CVD) and type-2 diabetes (T2D). Elevated FFA contribute to insulin resistance, production of inflammatory cytokines and expression of adhesion molecules on immune cells and endothelial cells, risk factors for CVD and T2D. Molecular mechanisms of FFA effects on monocyte function and how FFA phenotype is affected by healthy ageing remain poorly understood. This thesis evaluated the effects of the two major FFA in plasma, oleate and palmitate on monocyte viability, cel

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