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1

Klebensberger, Janosch. "Detergent-induced cell aggregation in Pseudomonas aeruginosa." [S.l. : s.n.], 2007. http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-26614.

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2

Östman, Johan. "Mechanisms involved in amyloid induced cytotoxicity." Doctoral thesis, Umeå universitet, Molekylärbiologi (Teknat- och Medfak), 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-541.

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Amyloidoses comprise a group of diseases where normal or mutated protein precipitates into amyloid fibrils. The deposition of fibrils causes dysfunction of organs and toxicity to nervous tissue. Up to date, 24 different proteins and peptides are known to be able to form amyloid fibrils. The most well known are Amyloid beta peptide and Prione protein causing Alzheimer’s disease and Creutzfeld Jacob’s disease respectively. The aims of this thesis were to investigate the structural properties of cytotoxic amyloid and examine the mechanisms involved. The model protein mostly used in the studies wa
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3

Menzen, Tim Andreas. "Temperature-induced unfolding, aggregation, and interaction of therapeutic monoclonal antibodies." Diss., Ludwig-Maximilians-Universität München, 2014. http://nbn-resolving.de/urn:nbn:de:bvb:19-175200.

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4

Nyström, Roger. "Aggregation of calcium carbonate dispersions induced by electrolytes and polyelectrolytes /." Åbo : Åbo akademi University, 2004. http://catalogue.bnf.fr/ark:/12148/cb40124838x.

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5

Knight, Grady C. "The molecular chaperone α-crystallin protects proteins from UV-induced aggregation". Diss., Georgia Institute of Technology, 1999. http://hdl.handle.net/1853/30486.

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6

Xu, Meisheng. "The field-induced aggregation and magneto-optical properties in magnetic fluids." Thesis, London South Bank University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300592.

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7

Dong, Yujie. "Synthesis, photophysical properties and applications of aggregation-induced emission materials based on cyanostilbene moiety." HKBU Institutional Repository, 2016. https://repository.hkbu.edu.hk/etd_oa/313.

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The concept of "aggregation-induced emission" (AIE) effect has induced a great deal of attention these days. Now, exploration of new AIE-active molecular system and multiple high technique applications for AIE materials are the two research hotspots. Cyanostilbene, as a classical structural unit in photoelectric functional materials, also exhibited this unique luminescence behavior. The research background was illustrated in Chapter 1, which mainly introduced the development of this subject. In this project, Chapter 2 and Chapter 3 presented two classes of functionalized AIE-active molecules b
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Yu, Wai Hong. "Synthesis, Characterization and application studies of new aggregation-induced emission (AIE)-active materials." HKBU Institutional Repository, 2018. https://repository.hkbu.edu.hk/etd_oa/496.

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The structural design, synthesis and characterization of luminogens with aggregation-induced emission (AIE) properties are studied in this thesis. The remarkable emission properties, thermal stability and biocompatibility of the AIE-active materials demonstrate the promising applications in bioimaging and organic light-emitting diodes (OLEDs).;Chapter 1 introduces the existence of aggregation-caused quenching (ACQ) effect in most conventional organic dyes as well as phosphorescent transitional metal complexes. Discovery of AIE and its mechanical study allow further exploration of usage in orga
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Brummitt, Rebecca K. "Urea-induced dissociation of non-native aggregates of alpha-Chymotrypsinogen A kinetics, thermodynamics, and competing pathways /." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 103 p, 2008. http://proquest.umi.com/pqdweb?did=1597632641&sid=12&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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Photchanachai, Songsin. "Studies on Molecular Aggregation and Degradation of Food Proteins Induced by High-Temperature Treatments." Kyoto University, 2003. http://hdl.handle.net/2433/148327.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第10507号<br>農博第1380号<br>新制||農||882(附属図書館)<br>学位論文||H15||N3862(農学部図書室)<br>UT51-2003-U477<br>京都大学大学院農学研究科応用生命科学専攻<br>(主査)教授 北畠 直文, 教授 小川 正, 教授 吉川 正明<br>学位規則第4条第1項該当
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Cassidy, James. "Parsing The Aggregation- and Photodegradation-Induced Effects of Rhodamine-Sensitized Tio2 and Zro2 Films." W&M ScholarWorks, 2017. https://scholarworks.wm.edu/etd/1499450063.

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The impact of rhodamine aggregates on the photophysical properties of rhodamine dyes adsorbed to TiO2 were investigated using diffuse reflectance spectroscopy, steady-state fluorescence, and time-correlated single photon counting (TCSPC). Photocatalyzed de-alkylation of rhodamine dyes containing tertiary amine groups (5-ROX, R101, and RB) was observed on TiO2, which resulted in a ~50 nm hypsochromic shift. Therefore, concentration dependent diffuse reflectance spectra of R560/TiO2 samples, which contained primary amines, demonstrated the formation of H- and J-aggregates at the expense of the m
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Suenaga, Kazumasa. "Precise Control of Highly-Efficient Solid-Emissive Property of Boron Ketoiminate." Kyoto University, 2019. http://hdl.handle.net/2433/242531.

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付記する学位プログラム名: 充実した健康長寿社会を築く総合医療開発リーダー育成プログラム<br>Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(工学)<br>甲第21793号<br>工博第4610号<br>新制||工||1718(附属図書館)<br>京都大学大学院工学研究科高分子化学専攻<br>(主査)教授 田中 一生, 教授 秋吉 一成, 教授 大内 誠<br>学位規則第4条第1項該当
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13

Xu, Alan. "Atomic scale characterisation of radiation damage and radiation induced precipitation in tungsten-rhenium alloys." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:1ae33661-c81f-4e77-a80c-bc12ed9123d9.

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Tungsten is considered the prime candidate material for plasma facing components within fusion reactors. However, exposure of tungsten to neutron flux brings about transmutation of tungsten into by-products: Re, Os and Ta. Under increasing levels of radiation damage, irradiation induced clustering/precipitation takes place that embrittles and thus reduces lifetime of such tungsten components. This thesis was undertaken to explore this subject on a deeper level. There are three components to this study. The first part considers the effect of Re content on irradiation induced clustering. Lab-mad
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14

Ohtani, Shunsuke. "Creation of Emissive and Functional Materials Based on Fused-Boron Complexes." Kyoto University, 2021. http://hdl.handle.net/2433/261618.

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15

Andersson, Karin, M. Pokrzywa, Ingrid Dacklin, and Erik Lundgren. "Inhibition of TTR aggregation-induced cell death : a new role for serum amyloid P component." Umeå universitet, Institutionen för molekylärbiologi (Medicinska fakulteten), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-65622.

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BACKGROUND: Serum amyloid P component (SAP) is a glycoprotein that is universally found associated with different types of amyloid deposits. It has been suggested that it stabilizes amyloid fibrils and therefore protects them from proteolytic degradation. METHODOLOGY/PRINCIPAL FINDINGS: In this paper, we show that SAP binds not only to mature amyloid fibrils but also to early aggregates of amyloidogenic mutants of the plasma protein transthyretin (TTR). It does not inhibit fibril formation of TTR mutants, which spontaneously form amyloid in vitro at physiological pH. We found that SAP prevents
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Tabuchi, Arata. "Direct demonstration of involvement of protein kinase Cα in the Ca[2+]-induced platelet aggregation". Kyoto University, 2003. http://hdl.handle.net/2433/148479.

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Ling, Karen Kar Yun. "The role of P2Y1̳ nucleotide receptor in agrin-induced AChR aggregation at the neuromuscular junctions /." View Abstract or Full-Text, 2002. http://library.ust.hk/cgi/db/thesis.pl?BIOL%202002%20LING.

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Thesis (M. Phil.)--Hong Kong University of Science and Technology, 2002.<br>On t.p. "1̳" is subscript. Includes bibliographical references (leaves 114-141). Also available in electronic version. Access restricted to campus users.
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18

Merg, Martina [Verfasser]. "Aggregation during biopharmaceutical production of antibodies induced by UV radiation and interface exposure / Martina Merg." Ulm : Universität Ulm, 2017. http://d-nb.info/1131710495/34.

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19

Arribat, Mathieu. "Acides aminés phosphole ou silole : vers de nouvelles sondes fluorescentes pour un marquage de peptide innovant." Thesis, Montpellier, 2018. http://www.theses.fr/2018MONTS144.

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La première partie de ces travaux de thèse concerne la synthèse d’acides aminés phosphole par formation d’une liaison P-C. Les propriétés de fluorescence (absorption, émission et rendement quantique) sont modulées à la fois par les différents substituants présents sur le phosphore (BH3, O, S…) ainsi que par le squelette aromatique du phosphole. Des couplages peptidiques modèles réalisés en solution et sur support solide démontrent la possibilité d’intégrer ces acides aminés dans des peptides d’intérêts. La deuxième partie concerne la synthèse de nouveaux phospholes fonctionnalisés ainsi que d’
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20

Ito, Shunichiro. "Synthesis and Photophysical Properties of Functional Luminescent Materials Based on β-Diiminate Complexes Composed of Main-Group Metals". Doctoral thesis, Kyoto University, 2020. http://hdl.handle.net/2433/245840.

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京都大学<br>0048<br>新制・課程博士<br>博士(工学)<br>甲第22155号<br>工博第4659号<br>新制||工||1727(附属図書館)<br>京都大学大学院工学研究科高分子化学専攻<br>(主査)教授 田中 一生, 教授 秋吉 一成, 教授 古賀 毅<br>学位規則第4条第1項該当<br>Doctor of Philosophy (Engineering)<br>Kyoto University<br>DGAM
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Dong, Lei. "Conception et synthèse de glyco-sondes fluorescentes pour des applications en détection." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE1153/document.

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Avec le progrès scientifique et les besoins sociétaux, diverses méthodes de détection spécifiques et sensibles des métaux, des protéines et d’autres biomolécules sont largement utilisées dans la protection de l’environnement, la surveillance des maladies, la pharmacothérapie, la production agricole, l’industrie et d’autres domaines importants. Les sondes fluorescentes sont largement développées sur la base des phénomènes de transfert d’énergie (ICT, PET, FRET) et appliquées par exemple à la détection de contaminants ou à l'imagerie cellulaire. Mais l’effet d’agrégation (ACQ) atténue généraleme
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Nylander, Sven. "Thrombin/ADP-induced platelet activation and drug intervention /." Linköping : Univ, 2005. http://www.bibl.liu.se/liupubl/disp/disp2005/med885s.pdf.

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23

Menzen, Tim Andreas [Verfasser], and Wolfgang [Akademischer Betreuer] Frieß. "Temperature-induced unfolding, aggregation, and interaction of therapeutic monoclonal antibodies / Tim Andreas Menzen. Betreuer: Wolfgang Frieß." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2014. http://d-nb.info/1060632438/34.

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Lau, Wai Sum. "Synthesis, characterization and application studies of cyanostilbene-based molecular materials with aggregation-induced emission (AIE) characteristics." HKBU Institutional Repository, 2014. https://repository.hkbu.edu.hk/etd_oa/70.

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The molecular design, synthesis, spectroscopic and photophysical characterization of a series of cyanostilbene-based compounds are studied in this thesis. The thermal, electrochemical and aggregation induced emission (AIE) properties of these cyanostilbene-based compounds, as well as their application in organic lighting-emitting diodes, live cell imaging, chemical vapor sensor were investigated. Chapter 1 gives a brief introduction on the aggregation-caused quenching (ACQ) behavior of the conventional organic luminogens and the discovery and proposed mechanism of AIE phenomenon. Furthermore
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Wang, Jin-Hui. "Rhenium complexes based on triazolyl derivatives : from synthesis, structural and theoretical characterization to application as radiopharmaceuticals or fluorophores." Thesis, Toulouse 3, 2017. http://www.theses.fr/2017TOU30329/document.

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Les complexes de rhénium jouent un rôle important dans le domaine de la médecine nucléaire. Si pendant longtemps le rhénium a été utilisé comme modèle structural du technétium-99m, les caractéristiques physiques prometteuses des isotopes 186Re et 188Re, font des complexes de 186/188Re des candidats prometteurs en tant que radiopharmaceutiques thérapeutiques. De même, les propriétés intéressantes de photoluminescence des complexes de rhénium non-radioactifs en font d'excellents outils comme catalyseurs, matériaux luminescents et capteurs d'imagerie. Dans ce travail, notre objectif était (i) de
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Tominaga, Masato. "Functional π-Conjugated Materials Based on Structure of o-Carborane". 京都大学 (Kyoto University), 2014. http://hdl.handle.net/2433/188607.

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Weir, Steven. "Effect of fermentation media on the polymer-induced aggregation of microorganisms and the effect on subsequent centrifugation." Thesis, University of Huddersfield, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261466.

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28

Upamali, Karasinghe A. Nadeeka. "Carbazole-Based, Self-Assembled, Π-Conjugated Systems As Fluorescent Micro And Nanomaterials - Synthesis, Photophysical Properties, Emission Enhancement And Chemical Sensing". Bowling Green State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1323099511.

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Dong, Wenyue [Verfasser]. "The Design and Synthesis of Conjugated Polymers with Aggregation-Induced Emission and Their Application in Fluorescence Sensing / Wenyue Dong." Wuppertal : Universitätsbibliothek Wuppertal, 2015. http://d-nb.info/1076929885/34.

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Dewsbury, Bryan M. "Artificially induced aggregation of fauna and their effects on nutrient regimes and primary producers in an oligotrophic subtropical estuary." FIU Digital Commons, 2006. http://digitalcommons.fiu.edu/etd/2786.

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In order to investigate the role of faunal aggregations in concentrating nutrients in the oligotrophic landscape of Florida Bay, I manipulated faunal densities in Florida Bay sea grass beds by constructing artificial reefs. The effects of reefs and faunal aggregations on nutrient availability and benthic community structure were assessed. Over a year-long sampling period, artificial reefs had an average population of 50 fishes and crustaceans of various species. Faunal aggregation resulted in significant sediment organic matter decreases and sediment phosphorus increases. Plots with high fauna
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Yoshii, Ryosuke. "Synthesis of Highly-Functional Polymers Using Characteristics of Four-Coordinated Boron-Complexes with Boron-Nitrogen Bonds." 京都大学 (Kyoto University), 2014. http://hdl.handle.net/2433/188610.

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McKeon, Kristin Dianne. "Albumin Adsorption: Inferences of Protein Interactions Measured by Sedimentation both Between Species and Induced by Denaturing." Thesis, Virginia Tech, 2008. http://hdl.handle.net/10919/32082.

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Biological development and progression are managed by a diverse macromolecular group called proteins. Protein structure results from a complex folding process that leads to a final active form. This protein state is susceptible to changes in the surrounding environment and an incorrect structure can be produced. Changes in the protein conformation can lead to the formation of protein aggregates. Adsorption of proteins onto surfaces is utilized in many research analyses, but is capable of irreversibly changing the protein structure and causing aggregation. Albumin is a plasma protein that adsor
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Abeyawardhane, Dinendra L. "Biometal-Induced Structural Consequences of α-Synuclein – the Parkinson’s Disease Protein". VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/5909.

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The pre-synaptic protein α-Synuclein (αS) is often linked to the pathology of Parkinson’s disease (PD), an age-related neurodegenerative disorder. Lewy bodies, the cytopathological hallmarks of PD, are found to be rich in aggregates of misfolded αS protein. Metal dyshomeostasis has also been linked to PD due to the accumulation of iron in the substantia nigra pars compacta, and diminished copper levels reported in this same region. Metal dyshomeostasis in the brain coupled with oxidative stress can enhance the aggregation of αS. Recently, it was confirmed that mammalian αS is universally acety
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Shorikova, D. V. "The collagen-induced platelet aggregation and artery status in patients with arterial hypertension and heart failure with preserved ejection fraction." Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18601.

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Viglianti, L. "THE HETEROARYLETHENES: SYNTHESIS, ELECTROCHEMISTRY AND INVESTIGATION ON THE AGGREGATION-INDUCED EMISSION OF A PROMISING CLASS OF MOLECULES WITH LUMINESCENT PROPERTIES." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/338784.

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The present research has been aimed on the synthesis and to the electrochemical and photophysical investigation of the HeteroArylEthene class constituted by the DiThienylEthene DTE, TriThienylEthene TrTE, TetraThienylEthene TTE, DiFurylEthene DFE, TriFurylEthene TrFE and TetraFurylEthene TFE. The study includes as a benchmark the analogous phenyl-based series which was already well known concerning the synthesis the photophysical properties and the applications. A very limited knowledge was so far available concerning the heteroaryl-based ethenes. Among the investigated systems, TFE and TrTE
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Deng, Jiun-Ping, and 鄧君屏. "Shear induced aggregation in liquid suspensions." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/77288998096356858609.

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碩士<br>長庚大學<br>化工與材料工程研究所<br>93<br>The aggregation of an initially well-dispersed suspension of particulates due to shear-induced collision is examined in laminar flow and in turbulent flow. Experiments in laminar flow are conducted by a cone-and-plate device on latex particles suspended in aqueous glycerol while experiments in turbulent flow are conducted by stirred tank. The corresponding shear rate in laminar flow and in turbulent flow is calculated as a function of the stirring rate. The rate of aggregation growth is measured as a function of time for different constant shear rate and suspe
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Lee, Tai-chun, and 李岱軍. "Conformation Induced Molecular Aggregation in Poly(3-hexylthiophene)." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/54207782765945143457.

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碩士<br>輔仁大學<br>化學系<br>98<br>In this research, we’d like to study the morphology of P3HT in solution by controlling spin rate in solution state and also its morphology in films. UV-Vis and PL were used to monitor the state of aggregation under different shear force. Viscosity measurements were conducted to elucidate molecular conformation of P3HT in solution and to explain the results from UV-Vis and X-ray measurements. We found morphology of films prepared by aggregation of P3HT itself in solution was different from that prepared by extra shear force. Aggregation of P3HT itself in solution was
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Lin, Li-yang, and 林利陽. "Polypeptides containing luminescent units with aggregation-induced emission property." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/j25965.

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碩士<br>國立中山大學<br>材料與光電科學學系研究所<br>103<br>First chapter: Tetraphenylthiophene (TP) with aggregation-enhanced emission (AEE) property was used as terminal fluorophore of the water-soluble poly(γ-propargyl-L-glutamate) (PPLG)-based polymers of TP-PPLG-g-MEO2. In this study, we research various TP-PPLG-g-MEO2 affect aggregation of luminescence. In water, when concentration of TP-PPLG-g-MEO2 achieve CMC, TP-PPLG-g-MEO2 will aggregation to nanoparticle and suddenly increasing emission, and when heating over LCST, TP-PPLG-g-MEO2 will contract and also enhance emission. We use TP-PPLG-g-MEO2 “salt out ef
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Chang, Jui-Wen, and 張瑞文. "Aggregation-Induced Emission Characteristics of Tetraphenylethene-Capped Dipeptide Materials." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/43nzds.

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碩士<br>國立交通大學<br>材料科學與工程學系所<br>103<br>Supramolecular self-assembly hydrogel materials is ubiquitous in materials science and biology. Self-assembly provides routes to a range of materials with regular structures. And others advantages to developed in this process. In this thesis, we developed the novel dipeptide supramolecular hydrogel with self-assembly gelation enhanced fluorescence emission. Tetraphenylethene (TPE) is almost non-emissive when molecularly dissolved in solution but turns to be highly fluorescent in aggregate states. The hydrogelator was constructed by using the TPE as the hydr
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Lee, Ying-Nung, and 李怡儂. "Aggregation of SARS-CoV membrane protein induced by heat." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/31279254307817598750.

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碩士<br>慈濟大學<br>分子生物及細胞生物研究所<br>92<br>Severe acute respiratory syndrome (SARS) is a new respiratory illness caused by the infection of a novel coronavirus called SARS-CoV. Previous studies in our laboratory found that SARS-CoV membrane protein could be easily detected using Western blotting in non-denaturing condition but not in regular denaturing condition. Using Western blotting analysis and in vitro transcription /translation system (isotope-labeled), the aggregated membrane protein with the thermal denaturation (different temperature or different boiling time) was detected in the stacking ge
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Lin, Ya-Lin, and 林雅琳. "Platelet Aggregation Induced by Serotype Polysaccharide from Streptococcus mutans." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/15726071971429304067.

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碩士<br>國立臺灣大學<br>微生物學研究所<br>90<br>Abstract Infective endocarditis is characterized by the formation of vegetation, which is composed mainly of fibrin-platelet matrix, on damaged heart valves. Many bacterial proteins along with bacteria are able to activate platelets, and therefore play a crucial role in the pathogenesis because local activation of platelets contributes to the formation of vegetation. Using platelet aggregometry, we demonstrated in this study that Streptococcus mutans could aggregate platelets in rabbit platelet-rich plasma preparation in an irreversible and saturatio
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Huang, Pai-Ching, and 黃百慶. "Dexmedetomidine Enhances Adenosine Diphosphate-Induced Platelet Aggregation and Activation." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/77082214881544956058.

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碩士<br>中國醫藥大學<br>臨床醫學研究所碩士班<br>100<br>As an integral part in hemostasis, platelet has also been proved to play an important role in inflammation. Platelet activation was the very first step to participate in either hemostasis or inflammation. Many factors or molecules have been demonstrated as platelet stimulants. More and more platelet receptors were then discovered as well. The complicated networks of these receptor functions were composed of several distinct pathways. We could measure the different chemical products or physical phenomenons and thereby study the possible pathways in which wer
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Hsieh, Meng-Chieh, and 謝孟潔. "Aggregation Induced Photodynamic Therapy Enhancement of Binary Photosensitizers system." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/08756709360896622089.

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碩士<br>國立中興大學<br>生醫工程研究所<br>100<br>For the purpose to enhance the efficiency of PDT (photodynamic therapy) and extend its application; the binary system complexes were designed and synthesized with conjugating a chromophore (3, 6-bis-(1-methyl-4-vinyl- pyridinium) carbazole diiodide, BMVC) to mono-, bis- and trishydroxyl photosensitizers, respectively. BMVC plays the role of cancer cells recognizer; AIEE (aggregation-induced emission enhancement) generator and FRET (Fluorescence Resonance Energy Transfer) donor. The self assembling properties of these binary conjugates result in different degre
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Chen, Jyun-Wei, and 陳俊瑋. "Novel Aggregation-Induced Emission Fluorophores Applied on Cellular Studies." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/88facz.

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博士<br>國立中興大學<br>化學工程學系所<br>106<br>In this study, we focused on developing the newly organic molecules on the therapy and diagnosis of cancers. In the experiments, we synthesized some simple fluorescent organic molecules and enhanced their performances in the cells by the unique properties of Aggregation-Induced Emission (AIE). First, we synthesized an asymmetric 1, 6-disubstituted naphthalene (NV-12P), which can generate particular reactive oxygen species to undergo type I photodynamic therapy under irradiation. Furthermore, this compound can specifically localize in mitochondria in cancer cel
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Mandal, Kuheli. "Fluorescent Bioimaging Probe from Aggregation Induced Emission Active Molecule." Thesis, 2019. http://hdl.handle.net/10821/8341.

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LIN, YUN-RU, and 林韻茹. "Investigation of Aggregation-Induced-Emission Behavior for Tetraphenylethylene-Based Polymer." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/j97wv6.

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碩士<br>逢甲大學<br>化學工程學系<br>105<br>In this study, we successfully synthesized a small molecules with tetraphenylethylene as the basic structure and the correspounding polymer. Two methods were tested when small molecules was synthesized. The product synthesized by McMurry reaction found to be a good method for the synthesis of small molecules. The molecules were polymerized to obtain the corresponding macromolecule materials. Then, the absorption spectra, fluorescence spectra, aggregation-induced emission effect and quantum yield were measured, respectively. The results showed that the absorption
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Chang, Jean-Yun, and 張景雲. "TGF-beta induced aggregation of trafficking protein TRAPPC6A and apoptosis." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/77836481218037923263.

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碩士<br>國立成功大學<br>分子醫學研究所<br>97<br>Protein aggregation is central to the development of neurodegeneration such as Alzheimer’s disease. Here, we isolated a TGF-beta1-induced trafficking protein particle complex 6A, designated TPC6Adelta, which binds tumor suppressor WOX1 (also named WWOX or FOR). Compared to the wild type (22 kDa), TPC6Adelta has an N-terminal truncation of amino acid 29-42. TPC6A is a component of transport protein particle (TRAPP) complex in vesicle trafficking from ER to the Golgi complex in yeast. In contrast, mammalian TPC6A mainly localizes in the nuclei and at the per
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Przybycien, Todd Michael. "Structure, Function and Aggregation Kinetics in Salt-Induced Protein Precipitation." Thesis, 1989. https://thesis.library.caltech.edu/686/3/przybycien-tm_1989.pdf.

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<p>Salt-induced precipitation is a biological separation technique that exposes proteins to unnatural environments. Macromolecular-scale issues of activity, structure, and aggregation have been addressed as a function of governing parameters.</p> <p>The effects of salt type and concentration on protein solubility and recoverable activity were studied using α-chymotrypsin (αCT) as a model protein and five salts spanning the lyotropic series. Unaccounted for salt-protein interactions and changes in protein physical properties were the likely source of discrepencies between the experimental an
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(9748970), Hengming Qiu. "DNA Signal Induced Fusion And Aggregation Behaviors of Synthetic Cells." Thesis, 2020.

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This thesis investigates the use of engineered DNA to program fusion and aggregation behaviors of artificial cells, mimicking biological cells and their important functions. To achieve this goal, we construct synthetic cells from engineered lipids and DNA to recognize and process intercellular signals.<div><br></div><div>Cell fusion is regulated by snap receptor (SNARE) proteins in mammalian cells. The zippering of SNARE proteins exerts forces to the adjacent cell membrane and induces membrane fusion. The hybridization of membrane anchored DNA can induce fusion in a simil
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CHEN, PIN-RUEI, and 陳品叡. "Aggregation-induced emission in tetrasubstituted tetraphenylethene derivatives: synthesis and characterization." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/kj8s8y.

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碩士<br>逢甲大學<br>化學工程學系<br>107<br>Luminescent materials with aggregation-induced emission (AIE) properties have attracted many people's interest in recent years due to their application in, optoelectronic components, fluorescent probes, chemical sensor, and biosensor. Tetraphenylethene (TPE) is a compound that often used to investigate luminescence properties with significant AIE. In this study, TPE derivatives 9, 14, 15, 16, 18a-d with tetra-substituted structure were successfully synthesized, and their absorption spectra, fluorescence spectra, aggregation-induced luminescence, liquid fluorescen
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