Academic literature on the topic 'Aging Cyclic AMP Response Element-Binding Protein'

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Journal articles on the topic "Aging Cyclic AMP Response Element-Binding Protein"

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Atadja, P. W., K. F. Stringer, and K. T. Riabowol. "Loss of serum response element-binding activity and hyperphosphorylation of serum response factor during cellular aging." Molecular and Cellular Biology 14, no. 7 (1994): 4991–99. http://dx.doi.org/10.1128/mcb.14.7.4991.

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Human diploid fibroblasts undergo a limited number of population doublings in vitro and are used widely as a model of cellular aging. Despite growing evidence that cellular aging occurs as a consequence of altered gene expression, little is known about the activity of transcription factors in aging cells. Here, we report a dramatic reduction in the ability of proteins extracted from the nuclei of near-senescent fibroblasts to bind the serum response element which is necessary for serum-induced transcription of the c-fos gene. In contrast, the activities of proteins binding to the RNA polymeras
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Atadja, P. W., K. F. Stringer, and K. T. Riabowol. "Loss of serum response element-binding activity and hyperphosphorylation of serum response factor during cellular aging." Molecular and Cellular Biology 14, no. 7 (1994): 4991–99. http://dx.doi.org/10.1128/mcb.14.7.4991-4999.1994.

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Human diploid fibroblasts undergo a limited number of population doublings in vitro and are used widely as a model of cellular aging. Despite growing evidence that cellular aging occurs as a consequence of altered gene expression, little is known about the activity of transcription factors in aging cells. Here, we report a dramatic reduction in the ability of proteins extracted from the nuclei of near-senescent fibroblasts to bind the serum response element which is necessary for serum-induced transcription of the c-fos gene. In contrast, the activities of proteins binding to the RNA polymeras
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Kim, Hyo Geun, and Myung Sook Oh. "Memory-enhancing effect of Mori Fructus via induction of nerve growth factor." British Journal of Nutrition 110, no. 1 (2012): 86–94. http://dx.doi.org/10.1017/s0007114512004710.

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Fruits rich in phytochemicals have been shown to improve memory by protecting or enhancing neuronal functions mediated by neurotrophic factors, such as nerve growth factor (NGF), in the hippocampus. Mori Fructus (Morus alba L., Moraceae), also called mulberry, is used as a food, dietary supplement and an anti-ageing agent in traditional Oriental medicine. It is also known to contain abundant flavonoid compounds and to exhibit various pharmacological effects. The present study was performed to evaluate the memory-enhancing effect of Mori Fructus extract (ME) in mice, with a focus on NGF regulat
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Thome, Johannes, Fritz A. Henn, and Ronald S. Duman. "Cyclic AMP response element-binding protein and depression." Expert Review of Neurotherapeutics 2, no. 3 (2002): 347–54. http://dx.doi.org/10.1586/14737175.2.3.347.

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Reusch, Jane E. B., and Dwight J. Klemm. "Cyclic AMP Response Element-Binding Protein in the Vessel Wall." Circulation 108, no. 10 (2003): 1164–66. http://dx.doi.org/10.1161/01.cir.0000084296.45158.50.

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Sato-Bigbee, Carmen, and Robert K. Yu. "Presence of a Cyclic AMP Response Element-Binding Protein in Oligodendrocytes." Journal of Neurochemistry 60, no. 6 (1993): 2106–10. http://dx.doi.org/10.1111/j.1471-4159.1993.tb03495.x.

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Muneer, Iqra, Muhammad T. ul Qamar, Kishver Tusleem, Sadaf Abdul Rauf, Hafiz M. J. Hussain, and Abdul R. Siddiqi. "Discovery of selective inhibitors for cyclic AMP response element-binding protein." Anti-Cancer Drugs 30, no. 4 (2019): 363–73. http://dx.doi.org/10.1097/cad.0000000000000727.

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Carlstrom, Luke, Zun-ji Ke, James R. Unnerstall, Rochelle S. Cohen, and Subhash C. Pandey. "Estrogen Modulation of the Cyclic AMP Response Element-Binding Protein Pathway." Neuroendocrinology 74, no. 4 (2001): 227–43. http://dx.doi.org/10.1159/000054690.

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Qin, LiMei, Ron Bouchard, and Subbiah Pugazhenthi. "Regulation of cyclic AMP response element-binding protein during neuroglial interactions." Journal of Neurochemistry 136, no. 5 (2016): 918–30. http://dx.doi.org/10.1111/jnc.13497.

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Shankar, Deepa B., Jerry C. Cheng, and Kathleen M. Sakamoto. "Role of cyclic AMP response element binding protein in human leukemias." Cancer 104, no. 9 (2005): 1819–24. http://dx.doi.org/10.1002/cncr.21401.

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Dissertations / Theses on the topic "Aging Cyclic AMP Response Element-Binding Protein"

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Watt, William C. "Neuroplasticity in olfactory sensation /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/6252.

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Warwick, Helen Katharine. "Regulation of the cyclic AMP response element binding protein (CREB) by group I metabotropic glutamate receptors." Thesis, University of Leicester, 2005. http://hdl.handle.net/2381/29945.

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Initially, experiments investigated mGlu1/5 receptor signalling in recombinant CHO-lac cell lines, where receptor expression is under inducible control. Key differences in the signalling characteristics of the two receptor subtypes were apparent. Thus, whilst mGlula receptors activated a small, yet robust cyclic AMP response in the recombinant cell lines, mGlu5a receptors failed to stimulate significant cyclic AMP accumulation. Furthermore, in agreement with previous reports the patterns of Ca2+-mobilization activated by receptor stimulation also differed in these cells, with the mGlula recept
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Impey, Soren. "The role of CREB-dependent gene expression in neuronal plasticity and memory formation /." Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/6268.

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Rosenberg, Charles Dan. "Altération du facteur de transcription cyclic adenosine monophosphate responsive element binding protein [CREB] au cours de la tumorigenèse du cortex surrénalien." Paris 6, 2003. http://www.theses.fr/2003PA066293.

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Athos, Jaime Ian. "Calcium-stimulated signal transduction in long-term memory formation and neural plasticity /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/10641.

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Sanches, Talita Rojas Cunha. "Vias intracelulares da ação do Sildenafil no diabetes insipidus induzido pelo lítio." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/5/5148/tde-27082012-163342/.

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Os pacientes que usam lítio (Li) para tratamento do transtorno bipolar frequentemente apresentam poliúria e deficiência de concentração urinária, sintomas do Diabetes Insipidus Nefrogênico (DIN). Animais tratados com Li apresentam baixos níveis de produção de adenosina monofosfato cíclico (AMPc) em resposta ao hormônio antidiurético (HAD). O Sildenafil (Sil), um inibidor da fosfodiesterase 5 (PDE5), eleva os níveis intracelulares de guanosina monofosfato cíclico (GMPc), levando a inserção de aquaporina 2 (AQP2) na membrana plasmática das células do ducto coletor. Portanto, inibidores de PDE po
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Matlhagela, Keikantse. "Regulation of the sodium(+),potassium(+)-ATPase beta 1 gene by prostaglandin E(1): An interaction of cyclic adenosine 3'5'-monophosphate response element binding protein (CREB) and specificity protein 1 (Sp1) is critical for prostaglandin E(1)-dependent activation of the beta 1 promoter /." 2005. http://proquest.umi.com/pqdweb?did=982802751&sid=8&Fmt=2&clientId=39334&RQT=309&VName=PQD.

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Thesis (Ph.D.)--State University of New York at Buffalo, 2005.<br>Title from PDF title page (viewed on May 11, 2006) Available through UMI ProQuest Digital Dissertations. Thesis adviser: Taub, Mary. Includes bibliographical references.
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Book chapters on the topic "Aging Cyclic AMP Response Element-Binding Protein"

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Tanaka, K., S. Nogawa, D. Ito, et al. "Cyclic AMP Response Element Binding Protein Phosphorylation May Be Closely Associated with Neuroprotective Mechanisms After Focal Ischemia in Rat Brain." In Maturation Phenomenon in Cerebral Ischemia IV. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-59446-5_18.

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Leonard, Martin O., Susan O'Reilly, Katrina M. Comerford, and Cormac T. Taylor. "Identification of Cyclic AMP Response Element-Binding Protein-Dependent Transcriptional Responses in Hypoxia by Microarray Analysis." In Oxygen Sensing. Elsevier, 2004. http://dx.doi.org/10.1016/s0076-6879(04)81033-4.

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Royer, C., TFG Lucas, MFM Lazari, and CS Porto. "Estrogens Increase Cyclic AMP Response Element Binding Protein (CREB) Phosphorylation and Cyclin D1 Expression in Rat Sertoli Cells." In Posters I. Endocrine Society, 2010. http://dx.doi.org/10.1210/endo-meetings.2010.part2.p1.p2-21.

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Conference papers on the topic "Aging Cyclic AMP Response Element-Binding Protein"

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Cheung, Tracy M., and George A. Truskey. "Aging Endothelial Cells Exhibit Decreased Response to Atheroprotective Shear Stress." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14402.

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As endothelial cells (ECs) age, morphological and physiological changes occur that may alter macromolecular transport and cause subsequent disease development. ECs in atherosclerotic regions exhibit high cell turnover and high levels of oxidative stress due to transient flow patterns and low and oscillating shear stress. This leads to replicative or stress-induced senescence. Resveratrol indirectly reverses senescence-associated phenotypes via competitive inhibition of cAMP-degrading phosphodiesterases (PDEs). Elevated levels of membrane-associated cAMP activate the cyclic AMP-regulated guanos
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Park, Hee Sun, Sunhyae Jang, Hye Rim Cha, et al. "Abstract A18: Silver nanoparticles induce apoptosis by regulation of cyclic AMP response element-binding protein in lung cancer cells." In Abstracts: AACR International Conference on Frontiers in Cancer Prevention Research‐‐ Nov 7-10, 2010; Philadelphia, PA. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1940-6207.prev-10-a18.

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Park, Hee Sun, Sunhyae Jang, Hye Rim Cha, et al. "Abstract 4785: Silver nanoparticles induce apoptosis in squamous lung cancer cell by regulation of cyclic AMP response element-binding protein: regulating its upstream oxidative stress-dependent Ras signaling pathways." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-4785.

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