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Journal articles on the topic 'AGP'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Bindi, Luca, and Frank N. Keutsch. "Old defined minerals with complex, still unresolved structures: the case of stützite, Ag5−x Te3." Zeitschrift für Kristallographie - Crystalline Materials 233, no. 3-4 (2018): 247–53. http://dx.doi.org/10.1515/zkri-2017-2120.

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AbstractThe crystal structure of the mineral stützite, a relatively common silver telluride, was solved using intensity data collected using a crystal from the cotype material from the May Day mine, La Plata District, CO (USA). The study revealed that the structure is hexagonal, space groupP6̅, with cell parameters:a=13.454(2),c=8.459(1) Å andV=1326.0(5) Å3. The refinement of an anisotropic model led to anRindex of 0.0421 for 1950 independent reflections. In the crystal structure of stützite there are eight independent Te sites and eight Ag sites withZ=7. Only Ag5, Ag6, Ag7 and Ag8 form classi

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2

Kleczkowski, Leszek A., Per Villand, Anders Lönneborg, Odd-Arne Olsen, and Ernst Lüthi. "Plant ADP-Glucose Pyrophosphorylase -Recent Advances and Biotechnological Perspectives (A Review)." Zeitschrift für Naturforschung C 46, no. 7-8 (1991): 605–12. http://dx.doi.org/10.1515/znc-1991-7-817.

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Abstract Recent advances in studies on plant ADP -glucose pyrophosphorylase (AGP), the key enzyme of starch biosynthesis, are presented. AGP constitutesthe First committed and highly regulated step of starch synthesis in all plan ttissues. The importance of AGP in carbohydrate metabolism and several of its features, such as potent regulation by cellular effectors (3-phosphoglycerate and Pi), an unusual two subunit-types structure, tissue-specific and developmentally-regulated expression, and presence of the AGP -deficient mutants, make it an attractive, but complex, target forbiotechnological

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Zhou, Li, Oscar González Alvarez, Carmen Sans Mazon, Ling Chen, Huiping Deng, and Minghao Sui. "The roles of conjugations of graphene and Ag in Ag3PO4-based photocatalysts for degradation of sulfamethoxazole." Catalysis Science & Technology 6, no. 15 (2016): 5972–81. http://dx.doi.org/10.1039/c6cy00192k.

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Three different photocatalysts, namely silver phosphate (Ag<sub>3</sub>PO<sub>4</sub>; AGP), Ag<sub>3</sub>PO<sub>4</sub>-graphene (AGP–G) and Ag/Ag<sub>3</sub>PO<sub>4</sub>–graphene (AAGP–G), were fabricated by a chemical precipitation approach. The mechanism of AAGP–G to degrade SMX was explained in detail.

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Zhang, Xiao-Wei, Si-Yu Li, Ling-Ling Zhang, et al. "Structure and expression analysis of genes encoding ADP-glucose pyrophosphorylase large subunit in wheat and its relatives." Genome 59, no. 7 (2016): 501–7. http://dx.doi.org/10.1139/gen-2016-0007.

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ADP-glucose pyrophosphorylase (AGP), which consists of two large subunits (AGP-L) and two small subunits (AGP-S), controls the rate-limiting step in the starch biosynthetic pathway. In this study, a full-length open reading frame (ORF) of AGP-L gene (named as Agp2) in wheat and a series of Agp2 gene sequences in wheat relatives were isolated. The coding region of Agp2 contained 15 exons and 14 introns including a full-length ORF of 1566 nucleotides, and the deduced protein contained 522 amino acids (57.8 kDa). Generally, the phylogenetic tree of Agp2 indicated that sequences from A- and D-geno

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Miau, L. H., C. J. Chang, W. H. Tsai, and S. C. Lee. "Identification and characterization of a nucleolar phosphoprotein, Nopp140, as a transcription factor." Molecular and Cellular Biology 17, no. 1 (1997): 230–39. http://dx.doi.org/10.1128/mcb.17.1.230.

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Expression of the alpha-1 acid glycoprotein (AGP) gene (agp) is activated by a key transcription factor, AGP/enhancer-binding protein (AGP/EBP, commonly called C/EBP beta), in the liver during the acute-phase response. In addition to this positive regulation, agp is negatively regulated by nucleolin (T. H. Yang et al., Mol. Cell. Biol. 14:6068-6074, 1994). Other factors involve in positive regulation of the agp gene are poorly characterized. In a systematic search for factors that may interact with AGP/EBP, we have identified Nopp 140, a phosphoprotein of 140 kDa, by immunoaffinity chromatogra

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6

Ceciliani, Fabrizio, Vanessa Pocacqua, Cristina Lecchi та ін. "Differential expression and secretion of α1-acid glycoprotein in bovine milk". Journal of Dairy Research 74, № 3 (2007): 374–80. http://dx.doi.org/10.1017/s0022029907002646.

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α1-Acid glycoprotein (AGP) is a lipocalin that is produced mainly by the liver and secreted into plasma in response to infections and injuries. In this study, we evaluated AGP isoforms that can be detected in bovine milk. We found that milk-AGP content is made up of at least two isoform groups, a low MW group (44 kDa) that is produced in the mammary gland (MG-AGP), and a higher MW group (55–70 kDa), that is produced by somatic cells (SC-AGP). Identical SC-AGP isoforms can be found both in milk and blood PMN cells. Analysis of the mammary tissue cDNA showed that the sequence of the MG-AGP isofo

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Crestani, Bruno, Corinne Rolland, Bernard Lardeux та ін. "Inducible Expression of the α1-Acid Glycoprotein by Rat and Human Type II Alveolar Epithelial Cells". Journal of Immunology 160, № 9 (1998): 4596–605. http://dx.doi.org/10.4049/jimmunol.160.9.4596.

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Abstract α1-Acid glycoprotein (AGP) is a major acute phase protein in rat and human. AGP has important immunomodulatory functions that are potentially important for pulmonary inflammatory response. The liver is the main tissue for AGP synthesis in the organism, but the expression of AGP in the rat lung has not been investigated. We show that AGP mRNA was induced in the lung of dexamethasone-, turpentine-, or LPS-treated rats, whereas AGP mRNA was not detected in the lung of control rats. In the lung of animals treated intratracheally with LPS, in situ hybridization showed that AGP gene express

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8

Li, Xiaoping, Shudong Liu, Ji Li, Xiaohua Tan, Yilong Li, and Feng Wu. "Apparent Permeability Model for Gas Transport in Multiscale Shale Matrix Coupling Multiple Mechanisms." Energies 13, no. 23 (2020): 6323. http://dx.doi.org/10.3390/en13236323.

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Apparent gas permeability (AGP) is a significantly important parameter for productivity prediction and reservoir simulation. However, the influence of multiscale effect and irreducible water distribution on gas transport is neglected in most of the existing AGP models, which will overestimate gas transport capacity. Therefore, an AGP model coupling multiple mechanisms is established to investigate gas transport in multiscale shale matrix. First, AGP models of organic matrix (ORM) and inorganic matrix (IOM) have been developed respectively, and the AGP model for shale matrix is derived by coupl

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ATEMEZEM, Aurélie, Elisabeth MBEMBA, Roger VASSY, Hocine SLIMANI, Line SAFFAR та Liliane GATTEGNO. "Human α1-acid glycoprotein binds to CCR5 expressed on the plasma membrane of human primary macrophages". Biochemical Journal 356, № 1 (2001): 121–28. http://dx.doi.org/10.1042/bj3560121.

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We have reported previously that human α1-acid glycoprotein (AGP) inhibits the infection of human monocyte-derived macrophages (MDM) by R5 HIV-1, and that a disulphide-bridged peptide mimicking the clade B HIV-1 gp120 consensus V3 domain (V3Cs) binds specifically to CCR5 (the major co-receptor of R5 HIV strains) on these cells [Seddiki, Rabehi, Benjouad, Saffar, Ferriere, Gluckman and Gattegno (1997) Glycobiology 7, 1229–1236]. The present study demonstrates that AGP binds specifically to MDM at high- and low-affinity binding sites with Kd values of 16nM and 4.9μM respectively. The fact that h

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10

Fournier, Thierry, Najet Bouach, Christian Delafosse, Bruno Crestani та Michel Aubier. "Inducible Expression and Regulation of the α1-Acid Glycoprotein Gene by Alveolar Macrophages: Prostaglandin E2 and Cyclic AMP Act as New Positive Stimuli". Journal of Immunology 163, № 5 (1999): 2883–90. http://dx.doi.org/10.4049/jimmunol.163.5.2883.

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Abstract We have reported that α1-acid glycoprotein (AGP) gene expression was induced in lung tissue and in alveolar type II cells during pulmonary inflammatory processes, suggesting that local production of this immunomodulatory protein might contribute to the modulation of inflammation within the alveolar space. Because AGP may also be secreted by other cell types in the alveolus, we have investigated the expression and the regulation of the AGP gene in human and rat alveolar macrophages. Spontaneous AGP secretion by alveolar macrophages was increased 4-fold in patients with interstitial lun

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11

Lee, Y. M., L. H. Miau, C. J. Chang, and S. C. Lee. "Transcriptional induction of the alpha-1 acid glycoprotein (AGP) gene by synergistic interaction of two alternative activator forms of AGP/enhancer-binding protein (C/EBP beta) and NF-kappaB or Nopp140." Molecular and Cellular Biology 16, no. 8 (1996): 4257–63. http://dx.doi.org/10.1128/mcb.16.8.4257.

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Alpha-1 acid glycoprotein/enhancer-binding protein (AGP/EBP) (C/EBPbeta), a member of the C/EBP family, is one of the key transcription factors responsible for the induction of a wide array of genes, some of which are expressed during the acute-phase response. Both activator and repressor were shown to be encoded by the intronless agp/ebp or its rat and human homologs, which contain a common bZIP domain at their C-terminal regions. Expression of the AGP gene (agp) is regulated by AGP/EBP in liver during the acute-phase response. However, the molecular mechanism for this regulation is poorly un

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12

McCurdy, Teresa R., Varsha Bhakta, Louise J. Eltringham-Smith, Sharon Gataiance, Alison E. Fox-Robichaud, and William P. Sheffield. "Comparison of Methods for the Purification of Alpha-1 Acid Glycoprotein from Human Plasma." Journal of Biomedicine and Biotechnology 2011 (2011): 1–9. http://dx.doi.org/10.1155/2011/578207.

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Alpha-1 acid glycoprotein (AGP) is a highly glycosylated, negatively charged plasma protein suggested to have anti-inflammatory and/or immunomodulatory activities. Purification of AGP could be simplified if methods that exploit its high solubility under chemically harsh conditions could be demonstrated to leave the protein in its native conformation. Procedures involving exposure of AGP to hot phenol or sulphosalicylic acid (SSA) were compared to solely chromatographic methods. Hot phenol-purified AGP was more rapidly cleared from mice in vivo following intravenous injection than chromatograph

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13

Letlole, Bakang R., Ellen P. C. W. Damen та Christine Jansen van Rensburg. "The Effect of α-Monolaurin and Butyrate Supplementation on Broiler Performance and Gut Health in the Absence and Presence of the Antibiotic Growth Promoter Zinc Bacitracin". Antibiotics 10, № 6 (2021): 651. http://dx.doi.org/10.3390/antibiotics10060651.

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The use of antibiotic growth promoters (AGP) is common practice to improve broiler production and performance. The use of AGP is under discussion as it can induce bacterial resistance. The purpose of this study was to determine the impact of removing AGP from broiler feed and study the effect of feed additives. For those countries where in-feed AGP are still permitted, the effect of the products in the presence of AGP was evaluated. Half the number of male broilers received a diet free of AGP, whereas the other half received a diet supplemented with zinc bacitracin at 0.5 g/kg. Both diets were

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14

Baida, Samuel, Enda King, Shane Gore, Chris Richter, Andrew Franklyn-Miller, and Kieran Moran. "Movement Variability and Loading Characteristics in Athletes With Athletic Groin Pain: Changes After Successful Return to Play and Compared With Uninjured Athletes." Orthopaedic Journal of Sports Medicine 10, no. 10 (2022): 232596712211251. http://dx.doi.org/10.1177/23259671221125159.

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Background: Athletic groin pain (AGP) can lead to altered movement patterns during rapid deceleration and acceleration. However, the effect of AGP on movement variability and loading patterns during such actions remains less clear. Purpose: To investigate, using a continuous lateral hurdle hop task, how movement variability and magnitude measures of 3-dimensional (3D) kinematic, kinetic, and vertical ground-reaction force (vGRF) variables are (1) affected by AGP (AGP vs uninjured controls [CON]) and (2) changed after successful rehabilitation (AGP prerehabilitation vs AGP postrehabilitation vs

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15

Affandi, Aan. "Dampak Pelarangan Antibiotic Growth Promoters (AGP) Dalam Pakan Terhadap Produksi Dan Mortalitas Ayam Pedaging: Studi Kasus Di Farm Peternak Ayam Ras Pedaging Di Kabupaten Kuningan." Jurnal Nutrisi Ternak Tropis dan Ilmu Pakan 6, no. 1 (2024): 35–48. http://dx.doi.org/10.24198/jnttip.v6i1.51273.

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Pada tahun 2017 pemerintah mengeluarkan peraturan terkait pelarangan Antibiotic Growth Promoters (AGP) dalam pakan. Untuk mengetahui dampak aturan tersebut terhadap peternak dilakukan penelitian di perusahaan peternakan di Kabupaten Kuningan yang memiliki mitra peternak. Penelitian mengambil data produksi dari peternak ayam pedaging meliputi data rataan berat badan, feed intake (FI), feed convertion ratio (FCR), persentase kematian (mortalitas), indeks prestasi peternak (IP) dan efisiensi pakan (EP). Data diperoleh dari tiap siklus produksi dengan data sampel dari hasil produksi beberapa peter

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16

Correa, SS, GN Mauldin, GE Mauldin, and SC Mooney. "Serum alpha 1-acid glycoprotein concentration in cats with lymphoma." Journal of the American Animal Hospital Association 37, no. 2 (2001): 153–58. http://dx.doi.org/10.5326/15473317-37-2-153.

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Serum alpha 1-acid glycoprotein (AGP) concentrations were evaluated in nine cats with lymphoma. Twenty-five healthy cats were used as controls. Blood samples were obtained from cats with lymphoma prior to induction chemotherapy, one week following induction, at complete response, and at monthly intervals. The median pretreatment AGP concentration for the nine cats with lymphoma was significantly higher than the median AGP concentration for the 25 control cats. Remission serum AGP concentration was not significantly different from the pretreatment AGP concentration in the cats with lymphoma. Se

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17

Pukhalsky, A. L., S. D. Shyian, E. A. Kalashnikova, G. V. Shmarina, D. A. Pukhalskaya та N. V. Bovin. "Immunomodulating activities of a natural α1-acid glycoprotein and its carbohydrate chains attached to the Protein-Free Polymer". Mediators of Inflammation 7, № 2 (1998): 115–18. http://dx.doi.org/10.1080/09629359891270.

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Immunomodulating effects of a neoglycoconjugate created on the basis of α1-acid glycoprotein (AGP) carbohydrate chains and synthetic protein-free carrier have been investigated. It was demonstrated that this pseudo-AGP suppressed PHA- or anti-CD3 antibody-induced lymphocyte proliferation in a dosedependent manner. Pseudo-AGP revealed a similar antiproliferative effect as the natural AGP samples. Stimulation of the LPS-induced proinflammatory cytokine production by m ononuclear cells treated with both natural and pseudo-AGP has been also demonstrated. These data show that carbohydrate chains of

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Jackson, Owen, Oliver Taylor, David G. Adams, and J. Paul Knox. "Arabinogalactan Proteins Occur in the Free-Living Cyanobacterium Genus Nostoc and in Plant–Nostoc Symbioses." Molecular Plant-Microbe Interactions® 25, no. 10 (2012): 1338–49. http://dx.doi.org/10.1094/mpmi-04-12-0095-r.

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Arabinogalactan proteins (AGP) are a diverse family of proteoglycans associated with the cell surfaces of plants. AGP have been implicated in a wide variety of plant cell processes, including signaling in symbioses. This study investigates the existence of putative AGP in free-living cyanobacterial cultures of the nitrogen-fixing, filamentous cyanobacteria Nostoc punctiforme and Nostoc sp. strain LBG1 and at the symbiotic interface in the symbioses between Nostoc spp. and two host plants, the angiosperm Gunnera manicata (in which the cyanobacterium is intracellular) and the liverwort Blasia pu

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Ceciliani, Fabrizio, та Cristina Lecchi. "The Immune Functions of α1Acid Glycoprotein". Current Protein & Peptide Science 20, № 6 (2019): 505–24. http://dx.doi.org/10.2174/1389203720666190405101138.

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α1-acid glycoprotein (orosomucoid, AGP) is an Acute Phase Protein produced by liver and peripheral tissues in response to systemic reaction to inflammation. AGP functions have been studied mostly in human, cattle and fish, although the protein has been also found in many mammalian species and birds. AGP fulfils at least two set of functions, which are apparently different from each other but in fact intimately linked. On one hand, AGP is an immunomodulatory protein. On the other hand, AGP is one of the most important binding proteins in plasma and, beside modulating pharmacokinetics and pharma

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Levander, Louise, Peter Påhlsson, Magnus Grenegård та Peter Gunnarsson. "α1-acid glycoprotein (AGP)-induced platelet shape change involves the Rho/Rho kinase signalling pathway". Thrombosis and Haemostasis 102, № 10 (2009): 694–703. http://dx.doi.org/10.1160/th09-03-0156.

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Summaryα1-acid glycoprotein (AGP) is an acute-phase protein that contributes to inflammation processes.The role of AGP in platelet activation and thrombosis is, however, largely unknown.Therefore, we thoroughly investigated the effects of AGP on human platelets. Platelets were isolated from healthy volunteers and subsequently exposed to AGP. Platelet responses were monitored as change in light transmission, intracellular calcium concentration, light microscopy and protein phosphorylation by Western blot.We found that AGP induced platelet shape change independently of a second release of adenin

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Japutra, Bambang Rijanto, Ismoyowati Ismoyowati, and Novie Andri Setianto. "The Productivity of Non-AGP Broiler Small-Holder Businesses Based on Production, Economy and Social Demography." ANIMAL PRODUCTION 23, no. 2 (2021): 111–19. http://dx.doi.org/10.20884/1.jap.2021.23.2.96.

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The study investigated the productivity of smallholder broiler farming with and without AGP to identify the difference between the utilization and absence of antibiotic growth promoter (AGP) incorporated into the broiler feed based on production (feed efficiency and cumulative performance index), economy (farming capacity and income), and socio-demography (farmers’ education background, age, farming experience, and farming motivation) in Central Java Province. The study was conducted through a survey of broiler farmers in one partnership company. The data analysis included analysis of variance

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Hsiao, Sheng-Yuan, Yun-Ru Lai, Chia-Te Kung та ін. "α-1-Acid Glycoprotein Concentration as an Outcome Predictor in Adult Patients with Sepsis". BioMed Research International 2019 (12 червня 2019): 1–9. http://dx.doi.org/10.1155/2019/3174896.

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Background. α-1-Acid glycoprotein (AGP) is an acute-phase protein that plays a role in first-line defense against infection and is therefore elevated in sepsis. We tested the hypothesis that AGP levels increase initially in sepsis and decrease after antimicrobial therapy and that these levels may predict treatment outcomes. Methods. AGP, biomarkers widely used in clinical practice, and maximum 24-h acute physiology and chronic health evaluation (APACHE)-II scores upon emergency department (ED) admission were prospectively evaluated and compared. We further examined changes in AGP concentration

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Khiar, Habiba, Fatima Zahra Janani, M’hamed Sadiq, Ghadah M. Al-Senani, Salhah D. Al-Qahtani, and Noureddine Barka. "Barium-Impregnated Ag3PO4 for Enhanced Visible Light Photocatalytic Degradation of Methyl Orange." Ceramics 8, no. 2 (2025): 44. https://doi.org/10.3390/ceramics8020044.

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In this study, we highlight the use of the alkaline earth metal barium (Ba) for the impregnation of Ag3PO4 (AgP). AgP was synthesized via co-precipitation and subsequently impregnated with a Ba2⁺-containing solution, followed by hydrothermal treatment to obtain Ba-AgP. The addition of barium significantly influenced both the crystallinity and crystallite size. Ba impregnation enhanced the crystallinity of AgP and promoted the growth of its crystallites. It was confirmed that Ba2⁺ was homogeneously distributed on the surface of AgP, with only a slight effect on particle shape. Ba-impregnated Ag

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Boyle, Catherine A., Robert W. Coatney, Alexandra Wickham, Suman K. Mukherjee, and LaVonne D. Meunier. "Alpha-1 Acid Glycoprotein as a Biomarker for Subclinical Illness and Altered Drug Binding in Rats." Comparative Medicine 71, no. 2 (2021): 123–32. http://dx.doi.org/10.30802/aalas-cm-20-000088.

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Alpha-1 acid glycoprotein (AGP) is a significant drug binding acute phase protein that is present in rats. AGP levels are known to increase during tissue injury, cancer and infection. Accordingly, when determining effective drug ranges and toxicity limits, consideration of drug binding to AGP is essential. However, AGP levels have not been well established during subclinical infections. The goal of this study was to establish a subclinical infection model in rats using AGP as a biomarker. This information could enhance health surveillance, aid in outlier identification, and provide more inform

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Diarra-Mehrpour, M., J. Bourguignon, I. Leroux-Nicollet та ін. "The effects of 17α-ethynyloestradiol and of acute inflammation on the plasma concentration of rat α1-acid glycoprotein and on the induction of its hepatic mRNA". Biochemical Journal 225, № 3 (1985): 681–87. http://dx.doi.org/10.1042/bj2250681.

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We measured the serum concentration of alpha 1-acid glycoprotein (alpha 1-AGP) and we evaluated the content of its hepatic mRNA in rats after 17 alpha-ethynyloestradiol treatment or after turpentine-induced acute inflammation, or after both treatments performed simultaneously. We have also studied the affinity of serum alpha 1-AGP for concanavalin A under these conditions. Both types of stimuli induce a marked retention of the glycoprotein on free concanavalin A. The serum concentration of alpha 1-AGP is increased about 14-fold compared with that in control rats when a single pharmacological d

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Omar, Haneen, Roa’ Fardous, Yasser M. Alhindi та ін. "α1-Acid Glycoprotein-Decorated Hyaluronic Acid Nanoparticles for Suppressing Metastasis and Overcoming Drug Resistance Breast Cancer". Biomedicines 10, № 2 (2022): 414. http://dx.doi.org/10.3390/biomedicines10020414.

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Robust inflammation-suppressing nanoparticles based on α1-acid glycoprotein (AGP)-conjugated hyaluronic acid nanoparticles (AGP-HA NPs) were designed to regulate breast cancer cells’ sensitivity to chemotherapy and to suppress tumor metastasis. The successful conjugation between AGP and HA NPs was confirmed using FTIR, zeta potential, and UV–vis spectroscopy. In vitro studies on MCF-7 cells indicated the remarkable ability of AGP-HA NPs in suppressing migratory tumor ability by 79% after 24 h. Moreover, the efficacy study showed the high capability of AGP-HA NPs in modulating MDA-MB-231 cells

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Jørgensen, Heather G., Moira A. Elliott, Elaine K. Allan, Christine E. Carr, Tessa L. Holyoake та Kevin D. Smith. "α1-Acid glycoprotein expressed in the plasma of chronic myeloid leukemia patients does not mediate significant in vitro resistance to STI571". Blood 99, № 2 (2002): 713–15. http://dx.doi.org/10.1182/blood.v99.2.713.

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Abstract Despite the efficacy of STI571 (Glivec, Novartis, Basle, Switzerland) in treating chronic myeloid leukemia (CML), drug resistance has already been noted both in vitro and in vivo. As plasma proteins, including alpha-1-acid glycoprotein (AGP), may reduce drug efficacy through binding, AGP was investigated for its ability to interact with STI571. At all stages of CML, AGP plasma level was significantly higher than in normal controls (P &lt; .05). The glycoprotein was purified from normal plasma and individual chronic myeloid leukemia (CML) patients' plasma by low-pressure chromatogr

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Hsu, Hung-Cheng, Pei-Wen Liao, Hsiang-Tzu Lee, Wei-Chen Liu, and Mei-Lin Ho. "Silver Nanoplates for Colorimetric Determination of Xanthine in Human Plasma and in Fish Meat via Etching/Aggregation/Fusion Steps." Sensors 20, no. 20 (2020): 5739. http://dx.doi.org/10.3390/s20205739.

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Silver nanoplates (AgP) were prepared and used in a colorimetric method for the evaluation of Xanthine (Xan) in blood plasma and fish meat. The detection mechanism for Xan was observed to occur via etching of AgP particles/aggregation/fusion steps, resulting in a color change from blue to grey. First, the basic Xan solution is adsorbed through partial substitution of capping molecules around the AgP with Xan, and then intermolecular hydrogen bonds form between AgP and AgP. Subsequently, the titrant Xan solution further etches the AgP and finally fuses particles together. Owing to the step by s

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Rydén, Ingvar, Peter Påhlsson та Stefan Lindgren. "Diagnostic Accuracy of α1-Acid Glycoprotein Fucosylation for Liver Cirrhosis in Patients Undergoing Hepatic Biopsy". Clinical Chemistry 48, № 12 (2002): 2195–201. http://dx.doi.org/10.1093/clinchem/48.12.2195.

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Abstract Background: Increased fucosylation of serum glycoproteins has previously been reported in patients with liver disease. We analyzed α1-acid glycoprotein (AGP) fucosylation in serum samples from patients investigated for suspected liver disease to evaluate its value as a biochemical marker for liver cirrhosis. Methods: We used a novel lectin immunoassay adapted to the AutoDELFIA system to analyze AGP fucosylation in 261 consecutive patients admitted for liver biopsy at Malmö University Hospital in Southern Sweden. The results were compared with histopathologic findings. In addition, AG

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Gannon, Bryan M., Marshall J. Glesby, and Saurabh Mehta. "3394 Alpha-1-acid glycoprotein as outcome, independent predictor, and effect modifier in a randomized, placebo-controlled, factorial trial of recombinant human growth hormone and rosiglitazone in people living with HIV." Journal of Clinical and Translational Science 3, s1 (2019): 33. http://dx.doi.org/10.1017/cts.2019.80.

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OBJECTIVES/SPECIFIC AIMS: In a randomized controlled trial in participants with HIV infection, recombinant human growth hormone (rhGH) reduced visceral adipose tissue (VAT); addition of rosiglitazone to rhGH prevented the accompanying decline in insulin sensitivity (SI). Within this parent RCT, we sought to determine the effect of rosiglitazone and rhGH intervention on alpha-1-acid glycoprotein (AGP), a biomarker of inflammation. We also investigated AGP as an independent risk factor for SI and VAT changes along with any potential effect modification by AGP of the intervention. METHODS/STUDY P

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Shu, Jiantao, Mingkun Yang, Cheng Zhang, Pingfang Yang, Feng Ge, and Ming Li. "Improving the Genome Annotation of Rhizoctonia solani Using Proteogenomics." Current Genomics 22, no. 5 (2021): 373–83. http://dx.doi.org/10.2174/1389202922666211011143957.

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Background: Rhizoctonia solani is a pathogenic fungus that causes serious diseases in many crops, including rice, wheat, and soybeans. In crop production, it is very important to understand the pathogenicity of this fungus, which is still elusive. It might be helpful to comprehensively understand its genomic information using different genome annotation strategies. Methods: Aiming to improve the genome annotation of R. solani, we performed a proteogenomic study based on the existing data. Based on our study, a total of 1060 newly identified genes, 36 revised genes, 139 single amino acid varian

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van Dijk, W., O. Pos, M. E. van der Stelt та ін. "Inflammation-induced changes in expression and glycosylation of genetic variants of α1-acid glycoprotein. Studies with human sera, primary cultures of human hepatocytes and transgenic mice". Biochemical Journal 276, № 2 (1991): 343–47. http://dx.doi.org/10.1042/bj2760343.

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The relative occurrence of genetic variants of human alpha 1-acid glycoprotein (AGP) in relation to changes in glycosylation was studied in sera of patients with burn injury, media of cytokine-treated primary cultures of human hepatocytes and Hep 3B cells, and sera of transgenic mice expressing the human AGP-A gene. It is concluded (i) that the glycosylation of AGP was not dependent on its genetic expression and (ii) that both the variants determined by the AGP-A gene as well as by the AGP-B/B' genes are increased after inflammation or treatment with interleukins 1 and 6.

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Baumann, H., and L. E. Maquat. "Localization of DNA sequences involved in dexamethasone-dependent expression of the rat alpha 1-acid glycoprotein gene." Molecular and Cellular Biology 6, no. 7 (1986): 2551–61. http://dx.doi.org/10.1128/mcb.6.7.2551-2561.1986.

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Synthesis of rat alpha 1-acid glycoprotein (AGP), one of the major inflammation-induced plasma proteins, is positively regulated by dexamethasone. To define the dexamethasone-responsive genetic element, we isolated and tested AGP gene sequences for the ability to confer glucocorticoid induction to the bacterial chloramphenicol acetyltransferase (CAT) gene in L cells. A 141-base-pair region of the AGP gene, including 120 base pairs of DNA upstream from the start site of transcription and 21 base pairs of the 5' untranslated region, was sufficient for maximal CAT gene induction by dexamethasone.

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Lee, Y. M., W. H. Tsai, M. Y. Lai, D. S. Chen, and S. C. Lee. "Induction of liver alpha-1 acid glycoprotein gene expression involves both positive and negative transcription factors." Molecular and Cellular Biology 13, no. 1 (1993): 432–42. http://dx.doi.org/10.1128/mcb.13.1.432-442.1993.

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Expression of the alpha-1 acid glycoprotein (AGP) gene is liver specific and acute phase responsive. Within the 180-bp region of the AGP promoter, at least five cis elements have been found to interact with trans-acting factors. Four of these elements (A, C, D, and E) interacted with AGP/EBP, a liver-enriched transcription factor, as shown by footprinting analysis and by an anti-AGP/EBP antibody-induced supershift in a gel retardation assay. Modification of these sites by site-directed mutagenesis coupled with transfection analysis indicated that AGP/EBP binding to all of these sites resulted

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Lee, Y. M., W. H. Tsai, M. Y. Lai, D. S. Chen, and S. C. Lee. "Induction of liver alpha-1 acid glycoprotein gene expression involves both positive and negative transcription factors." Molecular and Cellular Biology 13, no. 1 (1993): 432–42. http://dx.doi.org/10.1128/mcb.13.1.432.

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Expression of the alpha-1 acid glycoprotein (AGP) gene is liver specific and acute phase responsive. Within the 180-bp region of the AGP promoter, at least five cis elements have been found to interact with trans-acting factors. Four of these elements (A, C, D, and E) interacted with AGP/EBP, a liver-enriched transcription factor, as shown by footprinting analysis and by an anti-AGP/EBP antibody-induced supershift in a gel retardation assay. Modification of these sites by site-directed mutagenesis coupled with transfection analysis indicated that AGP/EBP binding to all of these sites resulted

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36

Baumann, H., and L. E. Maquat. "Localization of DNA sequences involved in dexamethasone-dependent expression of the rat alpha 1-acid glycoprotein gene." Molecular and Cellular Biology 6, no. 7 (1986): 2551–61. http://dx.doi.org/10.1128/mcb.6.7.2551.

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Abstract:

Synthesis of rat alpha 1-acid glycoprotein (AGP), one of the major inflammation-induced plasma proteins, is positively regulated by dexamethasone. To define the dexamethasone-responsive genetic element, we isolated and tested AGP gene sequences for the ability to confer glucocorticoid induction to the bacterial chloramphenicol acetyltransferase (CAT) gene in L cells. A 141-base-pair region of the AGP gene, including 120 base pairs of DNA upstream from the start site of transcription and 21 base pairs of the 5' untranslated region, was sufficient for maximal CAT gene induction by dexamethasone.

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Astria, Muhammad Vicky, Lud Waluyo, Roimil Latifa, Moh Mirza Nuryadi, Rr Eko Susetyarini, and Mohd Affendi Labo. "In Silico Analysis of 14-Deoxy 11, 12-Didehydro Andrographolide (AGP 2) from Sambiloto (Andrographis paniculata) as Drug Candidate Against SARS-CoV-2." HAYATI Journal of Biosciences 30, no. 3 (2023): 480–90. http://dx.doi.org/10.4308/hjb.30.3.480-490.

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The outbreak of the COVID-19 pandemic in the world has urged researchers to develop a vaccine or therapeutic drugs to fight this virus. This study aimed to assay 14 deoxy-11,12-didehydroandrographolide (AGP 2) ability as an inhibitor of 3-chymotrypsin like-protease (3CLPro), Papain-like protease (PLPro), and RNA-dependent RNA-polymerase (RdRp), the viral proteins of SARS-CoV-2 and to evaluate it safeness as a drug candidate. In-silico technique was performed in this study to analyze the binding interaction, complex stability between protein and ligand, and drug-likeness properties. The protein

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Zaetang, Yuwadee, Athika Wongkvanklom, Saengsuree Pangdaeng, et al. "Performance of Auto Glass Powder-High Calcium Fly Ash Geopolymer Mortar Exposed to High Temperature." Civil Engineering Journal 11, no. 6 (2025): 2343–58. https://doi.org/10.28991/cej-2025-011-06-010.

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Waste glass enhances concrete sustainability by reducing virgin material use and recycling waste. In traditional concrete, it boosts strength through pozzolanic reactions, while in geopolymer concrete, it improves durability, insulation, and resistance to harsh conditions. This study investigated the viability of substituting auto glass powder (AGP) for high-calcium fly ash (FA) in geopolymer mortar formulations. AGP was utilized as a substitute for high-calcium FA at substitution levels ranging from 0% to 40% by weight. The study examined the physical properties, compressive strength, thermal

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Duarte, Marcos Elias, and Sung Woo Kim. "Phytobiotics from Oregano Extracts Enhance the Intestinal Health and Growth Performance of Pigs." Antioxidants 11, no. 10 (2022): 2066. http://dx.doi.org/10.3390/antiox11102066.

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This study aimed to investigate the effects of phytobiotics on the intestinal health and growth performance of pigs. Totals of 40 newly-weaned pigs with 6.4 ± 0.3 kg BW (Exp. 1) and 120 growing pigs with 27.9 ± 2.3 kg BW (Exp. 2) were allotted in RCBD in a 2 × 2 factorial arrangement. The factors were: antibiotics as growth promoter (AGP) and phytobiotics (PHY). Pigs were fed experimental diets during 21 d (Exp. 1) and 42 d (Exp. 2). Growth performance, health parameters, and nutrient digestibility were evaluated. In Exp. 1, AGP diet increased (p < 0.05) ADG and G:F compared with a diet wit

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McCurdy, Teresa R., Varsha Bhakta, Louise J. Eltringham-Smith, Sharon Gataiance, Alison E. Fox-Robichaud, and William P. Sheffield. "In VivoClearance of Alpha-1 Acid Glycoprotein Is Influenced by the Extent of Its N-Linked Glycosylation and by Its Interaction with the Vessel Wall." Journal of Biomedicine and Biotechnology 2012 (2012): 1–11. http://dx.doi.org/10.1155/2012/292730.

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Alpha-1 acid glycoprotein (AGP) is a highly glycosylated plasma protein that exerts vasoprotective effects. We hypothesized that AGP’s N-linked glycans govern its rate of clearance from the circulation, and followed the disappearance of different forms of radiolabeled human AGP from the plasma of rabbits and mice. Enzymatic deglycosylation of human plasma-derived AGP (pdAGP) by Peptide: N-Glycosidase F yielded a mixture of differentially deglycosylated forms (PNGase-AGP), while the introduction of five Asn to Gln mutations in recombinantPichia pastoris-derived AGP (rAGP-N(5)Q) eliminated N-lin

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Aween, Yousef Abdulsamie, Punniyakoti Veeraveedu Thanikachalam, Mallikarjuna Rao Pichika, Sagineedu Sreenivasa Rao, and Belal J. Muhialdin. "Anti-inflammatory and anti-oxidative activities of andrographolide determined using atherosclerosis induced mice in Malaysia." Natural and Applied Sciences International Journal (NASIJ) 5, no. 1 (2024): 154–67. http://dx.doi.org/10.47264/idea.nasij/5.1.10.

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Atherosclerosis and relative cardiovascular complications remain the main reasons for death worldwide. This study stimulated atherosclerosis in C57BL/6J mice using P-407 via intraperitoneal injection, and treatment with Andrographolide (AGP) (15, 30 and 45 mg/kg BW) was carried out for six weeks. The heart and aorta were harvested after six weeks and assessed using Enzyme-Linked Immunosorbent Assay (ELISA) and histological studies. The results demonstrated that the treatment with AGP reversed the effects of P-407 induced atherosclerosis. The doses of AGP correlated with the reduction of athero

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Fu, Yansong, Siyi Zhang, Xin Zeng, and Hong Qin. "Association Between Alpha-1-Acid Glycoprotein and Non-Alcoholic Fatty Liver Disease and Liver Fibrosis in Adult Women." Metabolites 15, no. 4 (2025): 280. https://doi.org/10.3390/metabo15040280.

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Background: Alpha-1-acid glycoprotein (AGP) is a glycoprotein synthesized mainly by the liver. Nonalcoholic fatty liver disease (NAFLD) and liver fibrosis (LF) are associated with metabolic disorders. The aim of this study was to examine the potential correlation between AGP and both NAFLD and LF. Methods: The data were derived from the 2017–2023 National Health and Nutrition Examination Survey (NHANES). The linear association between AGP and NAFLD and LF was examined by multivariate logistic regression models. Non-linear relationships were described by fitting smoothed curves and threshold ef

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Chang, C. J., T. T. Chen, H. Y. Lei, D. S. Chen, and S. C. Lee. "Molecular cloning of a transcription factor, AGP/EBP, that belongs to members of the C/EBP family." Molecular and Cellular Biology 10, no. 12 (1990): 6642–53. http://dx.doi.org/10.1128/mcb.10.12.6642-6653.1990.

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A C/EBP-like transcription factor, AGP/EBP, that binds to three distinct motifs in the 5'-flanking region of alpha 1-acid glycoprotein gene (AGP) has been identified. Here we report the cloning and properties of cDNA corresponding to mouse AGP/EBP. AGP/EBP and C/EBP share 87% amino acid sequence homology in the "leucine zipper" and its associated DNA-binding domains, while their sequences outside these domains and the sizes of their mRNAs are different. Unlike the limited expression of C/EBP in tissues and cells, AGP/EBP appears to be ubiquitously expressed in tissues like lung, spleen, kidney

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44

Chang, C. J., T. T. Chen, H. Y. Lei, D. S. Chen, and S. C. Lee. "Molecular cloning of a transcription factor, AGP/EBP, that belongs to members of the C/EBP family." Molecular and Cellular Biology 10, no. 12 (1990): 6642–53. http://dx.doi.org/10.1128/mcb.10.12.6642.

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A C/EBP-like transcription factor, AGP/EBP, that binds to three distinct motifs in the 5'-flanking region of alpha 1-acid glycoprotein gene (AGP) has been identified. Here we report the cloning and properties of cDNA corresponding to mouse AGP/EBP. AGP/EBP and C/EBP share 87% amino acid sequence homology in the "leucine zipper" and its associated DNA-binding domains, while their sequences outside these domains and the sizes of their mRNAs are different. Unlike the limited expression of C/EBP in tissues and cells, AGP/EBP appears to be ubiquitously expressed in tissues like lung, spleen, kidney

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45

Ishaq, Musarat, Shailesh Kumar, Hilal Varinli, et al. "Atmospheric gas plasma–induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis." Molecular Biology of the Cell 25, no. 9 (2014): 1523–31. http://dx.doi.org/10.1091/mbc.e13-10-0590.

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Atmospheric gas plasmas (AGPs) are able to selectively induce apoptosis in cancer cells, offering a promising alternative to conventional therapies that have unwanted side effects such as drug resistance and toxicity. However, the mechanism of AGP-induced cancer cell death is unknown. In this study, AGP is shown to up-regulate intracellular reactive oxygen species (ROS) levels and induce apoptosis in melanoma but not normal melanocyte cells. By screening genes involved in apoptosis, we identify tumor necrosis factor (TNF)–family members as the most differentially expressed cellular genes upon

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Gregg, Brittany A., Paxton A. Parker, Kathryn M. Waller та ін. "Effects of central and peripheral administration of an acute-phase protein, α-1-acid-glycoprotein, on feed intake and rectal temperature in sheep". Journal of Animal Science 97, № 12 (2019): 4783–91. http://dx.doi.org/10.1093/jas/skz336.

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Abstract In rodents, an acute-phase protein, α-1-acid-glycoprotein (AGP), was shown to provide a link between inflammation and suppression of feed intake by acting as a leptin receptor agonist. The objective of this study was to determine the effects of AGP on feed intake and rectal temperature in sheep. Ewes were ovariectomized, implanted with a cannula into a lateral ventricle of the brain, and kept indoors in individual pens. Feed intake and rectal temperature were determined for sheep in all experiments. In the first experiment, ewes (n = 4) received 1 of 4 treatments [0 (control), 0.012 (

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Yoo, Juyoung, Taejun Yoon, Yong-Beom Park, Sung Soo Ahn, and Sang-Won Lee. "The Clinical Utility of Serum Alpha-1-Acid Glycoprotein in Reflecting the Cross-Sectional Activity of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Single-Centre Retrospective Study." Medicina 60, no. 8 (2024): 1212. http://dx.doi.org/10.3390/medicina60081212.

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Background and Objectives: This study investigated whether serum alpha-1-acid glycoprotein (AGP) at diagnosis could reflect the cross-sectional activity represented by the Birmingham vasculitis activity score (BVAS) and further predict poor outcomes during follow-up in patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV). Materials and Methods: This study included 70 patients with AAV. Clinical data at diagnosis, including AAV-specific indices and acute-phase reactants such as erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), were reviewed. All-cause m

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Thalmeier, Sabine, Arne Güssow, Mia K. Häuser, Natali Bauer, and Katarina Hazuchova. "Cat alpha-1-acid glycoprotein enzyme-linked immunosorbent assay: performance characteristics and reference intervals." Journal of Feline Medicine and Surgery 25, no. 5 (2023): 1098612X2311628. http://dx.doi.org/10.1177/1098612x231162836.

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Objectives The aim of this study was to evaluate performance of a feline-specific ELISA for the measurement of alpha-1-acid glycoprotein (AGP) and to establish a reference interval (RI). Methods Surplus serum samples with low (~200 µg/ml), medium (~450 µg/ml) and high (~745 and 930 µg/ml) AGP concentrations were used to assess the intra- and inter-assay coefficients of variation (CVs). The quality goal for bioanalytical method validation was a CV of <20%. Linearity was assessed by serial dilution of a sample with a high AGP concentration. Spike recovery was evaluated by mixing samples with

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Mullen, Deborah M., Richard M. Bergenstal, Mary Johnson, et al. "AGP Reports for Glucose and Insulin Devices Qualitative Study: What Patients and Clinicians Want." Science of Diabetes Self-Management and Care 51, no. 3 (2025): 333–44. https://doi.org/10.1177/26350106251337486.

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Purpose The purpose of the 2-phase study was to determine patient/family and clinician design preference, usability, and comprehension of ambulatory glucose profile (AGP) reports Methods A cross-sectional research design employing 2 phases was conducted. Patients and parents (n = 139) reviewed an educational guide and AGP report during a clinician consultation. They were directed to identify glucose trends before answering a design preferences and usability survey. Clinicians (n = 17) completed questionnaires about patients and personal experiences, design preferences, and expected future usab

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Romanelli, Pierpaolo, Walter Bertazzolo, Andrea Prisciandaro, Andrea Leone, Ugo Bonfanti, and Saverio Paltrinieri. "Measurement of Feline Alpha-1 Acid Glycoprotein in Serum and Effusion Using an ELISA Method: Analytical Validation and Diagnostic Role for Feline Infectious Peritonitis." Pathogens 13, no. 4 (2024): 289. http://dx.doi.org/10.3390/pathogens13040289.

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Background: Alpha-1 acid glycoprotein (AGP) may support a clinical diagnosis of feline infectious peritonitis (FIP). In this study, we assessed the analytical and diagnostic performances of a novel ELISA method to measure feline AGP. Methods: AGP was measured in sera and effusions from cats with FIP (n = 20) or with other diseases (n = 15). Precision was calculated based on the coefficient of variation (CV) of repeated testing, and accuracy was calculated by linearity under dilution (LUD). Results: The test is precise (intra-assay CVs: <6.0% in individual samples, <15.0% in pooled sample

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