Dissertations / Theses on the topic 'Ainu'
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Iori, Matteo. "Gli Ainu del Giappone." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/16083/.
Full textTeshima, Takemasa. "Toward the shattering of the myth of the mono-ethnic state : Japan, the Ainu, and the rights of indigenous peoples /." Thesis, Connect to this title online; UW restricted, 1995. http://hdl.handle.net/1773/10708.
Full textAakre, Bjørn Magne. "Ainu A culture of silence?" 名古屋大学大学院教育発達科学研究科 技術・職業教育学研究室, 2009. http://hdl.handle.net/2237/12377.
Full textTajima, Masakazu. "Complex predicate formation in Ainu." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=56904.
Full textThis thesis argues that a word is composed of lexical constituents and post-lexical constituents, and that the post-lexical constituents can incorporate into a verb, to form the complex predicate. This formational process is subject to syntactic constraints and principles. Therefore, I claim that the principles of universal grammar are also operative to word formation. This hypothesis will throw a new light upon the area of language acquisition of complex predicates.
Fukasawa, Yuriko. "Ainu archaeology as ethnohistory : iron technology among the Saru Ainu of Hokkaido in the 17th century." Thesis, University of Cambridge, 1995. https://www.repository.cam.ac.uk/handle/1810/272749.
Full textFukasawa, Yuriko. "Ainu archaeology as ethnohistory : iron technology among the Saru Ainu of Hokkaido, Japan, in the 17th century /." Oxford : J. & E. Hedges : Archaeopress, 1998. http://catalogue.bnf.fr/ark:/12148/cb370812928.
Full textYaguchi, Yujin. "The Ainu in United States-Japan relations." W&M ScholarWorks, 1999. https://scholarworks.wm.edu/etd/1539720321.
Full textSinatra, Natalia Francesca <1995>. "AINU MOSIR: IL LUNGO CAMMINO VERSO IL RICONOSCIMENTO GIURIDICO DELLO STATUS DI INDIGENOUS PEOPLE E LA TEORIZZAZIONE DELLA “NAZIONE AINU”." Master's Degree Thesis, Università Ca' Foscari Venezia, 2019. http://hdl.handle.net/10579/15969.
Full textOgawa, Masashi, and 小川正志. "Revival of cultural tradition amongst two ethnic minorities: Ainu in Japan and aborigines in Taiwan." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1995. http://hub.hku.hk/bib/B31950851.
Full textFrey, Christopher J. "Ainu schools and education policy in nineteenth-century Hokkaido, Japan." [Bloomington, Ind.] : Indiana University, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3292445.
Full textTitle from dissertation home page (viewed May 28, 2008). Source: Dissertation Abstracts International, Volume: 68-11, Section: A, page: 4636. Adviser: Heidi Ross.
Coulter-Pultz, Jude. "Exploring narratives in Ainu history through analysis of bear carvings." Thesis, Indiana University, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10119500.
Full textThe dominant narrative mode in Ainu studies today stresses an activist agenda that, although worthwhile, limits the potential for new research in the field. In this thesis, I analyze historical accounts of the development of Ainu bear carvings as a case study of the characteristics of the dominant activist mode and present an alternate narrative in order to demonstrate the need for a variety of approaches to Ainu research.
The activist narrative mode is structured to engender sympathy for Ainu people and respect for their cultural heritage. Activist accounts of Ainu bear carvings often claim that the carvers were pressured by the Japanese tourist industry to violate religious taboos against producing realistic depictions of bears. In this way, the carvings serve as a symbol of oppression of Ainu people under Japanese imperialism. At the same time, activist scholars state that the Ainu bear carvings followed a linear progression from tourist souvenirs to respected works of “fine art.” Thus, the carvings also reinforce optimistic projections regarding the future status of Ainu culture and socioeconomic condition.
My alternate narrative focuses on the complexities and ambiguities in the field and avoids judging events in moral or sympathetic terms. I explore a broad range of contextual issues, tracing the regional production of wooden bears from the paleolithic ancestors of Ainu people, examining the role of bears and woodcarving in Ainu culture, analyzing Ainu interactions with Japan, Russia, and other neighboring empires, and investigating the commodification of bear carvings as tourist souvenirs.
Activist narratives have contributed a wealth of valuable research to the field of Ainu studies and remain a useful tool for promoting social and cultural equality for Ainu people. However, automatic conformity to the dominant activist mode perpetuates the obfuscation of certain details in Ainu history, including the diversity within Ainu and Japanese cultures and institutions, instances of political cooperation between Ainu and Japanese communities, and unanswered questions regarding the complex development of Ainu cultural practices and beliefs. Although any historical account (including this thesis) inherently simplifies its subjects, varying our narrative approach helps us to identify and fill some of the gaps.
Corso, Elia Dal. "Ainu Evidentiality - a Semantico-Pragmatic Analysis and a Morphosyntactic Account." Doctoral thesis, SOAS University of London, 2018. http://hdl.handle.net/10278/3716752.
Full textOgawa, Masashi. "Revival of cultural tradition amongst two ethnic minorities Ainu in Japan and aborigines in Taiwan /." Click to view the E-thesis via HKUTO, 1995. http://sunzi.lib.hku.hk/hkuto/record/B31950851.
Full textBattipaglia, Sabrina. "The Ainu Ethnicity in Contemporary Japan: Museums, Parks and Reconstructed Villages." Doctoral thesis, Universitat Autònoma de Barcelona. Programa de Doctorat en Traducció i Estudis Interculturals, 2021. http://hdl.handle.net/10803/673324.
Full textEsta investigación se centra en la representación de la cultura tradicional ainu en museos al aire libre, parques culturales y pueblos reconstruidos en el Japón actual. Su principal objetivo es explorar cómo estos lugares están contribuyendo a la redefinición de la cultura ainu a través de prácticas de turistificación y mercantilización. La tesis sostiene que, más allá de las connotaciones negativas asociadas a estas prácticas, los museos al aire libre, los parques culturales y los pueblos reconstruidos pueden operar como vehículos complejos en los que la identidad ainu se negocia continuamente a través de la recreación y representación de su cultura tradicional. En este sentido, la tesis revisa los relatos históricos sobre los ainu, la conciencia política moderna y la revitalización cultural de sus comunidades, y la recepción de su cultura en Europa, específicamente, en Italia, a través de la consideración histórica de su influencia en el coleccionismo de arte, y su representación contemporánea en las obras del intelectual italiano Fosco Maraini y su importante papel en la difusión de la cultura ainu más allá de Japón. La musealización y la turistificación pueden formar parte de un proceso de mercantilización de la tradición cultural ainu cuyas consecuencias pueden parecer problemáticas y esencialmente negativas. Sin embargo, esta tesis sostiene que también hay un lado constructivo en este proceso, no exento de problemáticas, mediante el cual la cultura tradicional puede combinarse con elementos contemporáneos más fácilmente accesibles y transformarse en bienes comercializables con fines turísticos que preserven su existencia. A nivel metodológico, la tesis aplica las herramientas investigadoras del análisis histórico y los estudios culturales, integrando el análisis documental con algunas técnicas de investigación propias del análisis social, especialmente la entrevista.
This research focuses on the representation of Ainu traditional culture in open museums, cultural parks, and reconstructed villages in contemporary Japan. Its main objective is to explore how these places are contributing to the redefinition of Ainu culture through touristification and commodification practices. The thesis contends that, beyond the negative connotations associated to these practices, open museums, cultural parks, and reconstructed villages can operate as complex vehicles in which Ainu identity is continuously negotiated through the recreation and representation of its traditional culture. In this sense, the thesis reviews the historical accounts on the Ainu, the modern political awareness and cultural revitalization of their communities, and the reception of their culture in Europe, specifically, in Italy, through the historical consideration of its influence on art collecting, and its contemporary representation in the works of the Italian intellectual Fosco Maraini and his important role in the dissemination of Ainu culture beyond Japan. Musealization and touristification may indeed be part of a process of commodification of Ainu cultural traditions, one which can come across as problematic and quintessentially negative. However, this thesis argues that there is also a constructive side to this process by means of which, while unquestionably implying a form of compromise, traditional culture can be combined with more easily accessible contemporary elements and transformed into marketable goods for touristic purposes that preserve its existence. At the methodological level, the thesis applies the research tools of historical analysis and cultural studies, integrating the documentary analysis with some research techniques of social analysis, especially the interview.
Universitat Autònoma de Barcelona. Programa de Doctorat en Traducció i Estudis Interculturals
Leopardi, Federico <1994>. "Il ruolo delle scuole nella salvaguardia delle lingue Ainu e Ryūkyū." Master's Degree Thesis, Università Ca' Foscari Venezia, 2019. http://hdl.handle.net/10579/14176.
Full textCederlöf, Adam. "Samerna och ainu – två urfolks rätt och ickerätt till mark under koloniseringen." Thesis, Stockholms universitet, Avdelningen för japanska, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-119930.
Full textTanaka, Sakurako. "The Ainu of Tsugaru, the indigenous history and shamanism of northern Japan." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ48593.pdf.
Full textSiddle, Richard Matthew. "Racialisation and resistance : the evolution of Ainu-Wajin relations in modern Japan." Thesis, University of Sheffield, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296760.
Full textPolimeni, Rosario Maria <1991>. "Preservazione della lingua Ainu e language policy nel Giappone moderno e contemporaneo." Master's Degree Thesis, Università Ca' Foscari Venezia, 2018. http://hdl.handle.net/10579/13542.
Full textShapiro, Jonathan Chira. "Hyphenated Japan: Cross-examining the Self/Other dichotomy in Ainu-Japanese material culture." Oberlin College Honors Theses / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=oberlin1494762526392067.
Full textSjöberg, Katarina. "Mr. Ainu : cultural mobilization and the practice of ethnicity in a hierarchical culture /." Lund : Lund Univ, 1991. http://catalogue.bnf.fr/ark:/12148/cb37588919p.
Full textDal, Corso Elia <1989>. "Giapponese e Ainu: due lingue a contatto - Analisi di alcuni aspetti sintattico-funzionali." Master's Degree Thesis, Università Ca' Foscari Venezia, 2013. http://hdl.handle.net/10579/3867.
Full textConsolaro, Carolina <1992>. "Il "Poroto Kotan Ainu Museum" di Shiraoi: etnografia di un museo in trasformazione." Master's Degree Thesis, Università Ca' Foscari Venezia, 2020. http://hdl.handle.net/10579/16263.
Full textSjöberg, Katarina V. "The return of the Ainu : cultural mobilization and the practice of ethnicity in Japan /." Chur (Switzerland) : Harwood, 1993. http://catalogue.bnf.fr/ark:/12148/cb37440621g.
Full textBibliogr. p. 205-215. Glossaire. Index.
Wallner, Dominik [Verfasser], and Judit [Akademischer Betreuer] Árokay. "Die epische Erzähltradition der Ainu: Götterlieder (kamuy yukar) und Heldenepen (yukar) / Dominik Wallner ; Betreuer: Judit Árokay." Heidelberg : Universitätsbibliothek Heidelberg, 2021. http://d-nb.info/1235144291/34.
Full textFryzlewicz, Malgorzata. "The role of sound recordings in the revitalisation of minority languages of the Ainu People (Japan) and the West Frisians (the Netherlands)." Thesis, University of Plymouth, 2017. http://hdl.handle.net/10026.1/8638.
Full textClercq, Lucien. "Transformations socioculturelles des Aïnous du Japon : rapports de pouvoir, violence et résistance aborigène à Hokkaidô." Thesis, Paris, EHESS, 2017. http://www.theses.fr/2017EHES0040/document.
Full textThis research of ethnology studies the relationships of power between the Ainu, Japanese society and the Japanese State, and more specifically tries to shift the point of view of the majority concerning Aborigines and colonial conquest by studying the sociocultural transformations of the Ainu across the slow acquisition of Ezo by Japan. By studying historical archives combined with the data of ethnological fieldwork, it focuses on what the Ainu say about themselves and a past marked by the trauma of their incorporation into the Japanese national body after a long process of acculturation, which has relegated them to a precarious rank as an ethno-cultural minority. Both Japanese and Western historiographies concerning the colonization of the former island of Ezo, rely heavily on the conquerors’ perspective. These unilateral views obscure the existence of the Ainu’s own historiography, mostly silenced because of their forced material subordination. This allowed the colonial power to describe them as a vanished primitive people despite the fact that they created an exceptional international trading network in the past and possess a long history of resistance to domination. These archives and data from extended ethnographic fieldwork can help us to better understand this community and the events that shaped its history and that of Japan, and the long sequences of transformations of their respective socio-cultural and political organizations. Considering both the annexation of Ezo, as well as the long preparation that preceded it, the study of this set of data sheds light on the patterns of the colonial and postcolonial power’s governmentality, and efforts to manipulate the Ainu for political purposes, after having dehumanized and objectified them. This ethno-historical essay, in accordance with the more specific field of anthropology of violence in colonial and postcolonial contexts (violence can be symbolic when it takes on the occasional traits of racial discrimination and denial of existence, or ethnic, such as during the period of physical anthropology experiments or the long period following the Former Aborigines Act in 1899), seeks to take into account the historicity of previously little studied bibliographic and ethnographic sources. It also relies on long-term fieldwork with the Ainu. The result is a reinterpretation of the production of a history of power based exclusively on the State’s views and thoughts that aimed to minimize the Ainu’s existence to the point of relegating it to mere anecdote or possibly even rendering it invisible in the country’s history. Besides this critical situation, it appears that the Ainu are the creators and the holders of a historicity that has been denied for too long in order to better dispossess them. The Ainu, through academic exploitation as subjects of physical anthropology, appear to have been used in order to assess the practical application of Western colonial ideals and to support the modernization and creation of a Japanese colonial empire. Struggling desperately to free themselves from the shackles of the Former Aborigines Act of 1899 and from socio-cultural and academic violence by reversing stereotypes of ethnicity, the Ainu have patiently managed to integrate into the international network of indigenous activism, developing a vast cultural reinvention program focused on the main principles of autochthony. These analyses seek to shed new light on the Ainu’s way of thinking, the contemporary strategies to obtain the concrete application of their indigenous rights which they have managed to develop despite an unfavorable context, and to respond and react to the socio-cultural transformations they have been facing up to the present
本民族学調査は、アイヌと日本の国家並び社会とのあいだに生じる権力関係を対象とし、日本による漸進的なアイヌモシリ(北海道)占有の過程における、アイヌの社会文化的変容の考察を通じて、先住民と植民地主義的征服に関する多数派の観点を相対化することが目指される。本調査では、歴史資料に加え、現地での民族学調査に基づくデータを扱うが、それは、アイヌが自身とその過去について行う証言を重視するためである。アイヌによって語られる過去は、長きにわたる異文化受容の過程の後に、日本の国体に吸収され、文化民族的少数者という不安定な地位に追いやられたことに起因する外傷の痕跡を色濃く残している。一方、蝦夷ヶ島の植民に関する日本と西洋の史書は、基本的に征服者の視点に基づいており、それによれば、アイヌは並外れた交易のネットワークを築いていたにも関わらず、その強制的な物質的従属ははるか以前に遡るとみなされたり、また時にアイヌは既に消滅したものとみなされたりもする。つまりこれらの史書では、アイヌ自身の視点は端から隠蔽されているのである。従って、アイヌの共同体について、また、アイヌの歴史と日本の歴史における挿話を生み出してきた諸事件について、さらには、アイヌと日本双方の社会文化的・政治的な組織の変容の論理的筋道についてよりよく理解するためには、歴史資料のみならず、長年に渡る民族誌学的調査のデータを検討することが必要となるであろう。そして、こうしたデータの総体を検討することにより、蝦夷地の併合以降、並びに、それに先行する長い準備期間という、統治性に関わる二つの期間において、まずはアイヌを物化し、次いで政治的な目的で利用するための権力が、どのように形成されたのかが明らかとなるであろう。より厳密にいうのであれば、本民族誌学的試論は、コロニアル、ポストコロニアル的な状況下における暴力についての人類学という特殊領域に属し(その暴力は、人種差別や存在の否認といった限定的表現をとるときには象徴的なものとなり、形質人類学的実験や先住民に関する法律が施行されていた時期には民族的なものとなる)、アイヌのもとでの長年のフィールドワークに基礎をおきながら、これまであまり研究されてこなかった文献や民族誌学的情報の歴史性を重視し、そうすることで、アイヌの偉業を瑣末事とみなし、時に国史から抹消するまでに過小評価してきた、国家の言説に基づく権力の歴史の産物を相対化することを目指している。強権的な歴史観においては、アイヌからの収奪を促進するため、アイヌの歴史性は否定されてきたが、実際にはアイヌは、歴史性の創造者でありまたその保持者であるというのが本調査での見解である。自らを襲う幾多の変動に対し、アイヌは決して受動的であったわけではない。アイヌの共同体はむしろ、度重なる異文化受容の試練に対して発揮された、闘争性と強靭な抵抗力とによって特徴付けられるのであり、それは、数々の英雄的人物(往年の戦争指導者、芸術家、作家そして今日の活動家)の行動が示すとおりである。また、単一民族を自称する国家の内部で、アイヌに対する行政法的な地位(「北海道旧土人」)が設けられたという事実からは、この後、他の併合地域にも適応され、修正されていくこととなる、植民地支配のための機構を理論化しようとする国家の意志を読み取ることが可能である。さらにアイヌは、西洋から輸入された現代日本の新たな学識の形成のために重要な役割を果たしたと考えられるが、それは、黎明期にあった日本の形質人類学の研究対象として、学術的に利用されることによってなのである。これらの法的な拘束や、社会文化的・学究的な暴力の束縛からの解放を求めて激しく抵抗するなかで、アイヌは、自然と融合した未開人といった固定観念の価値を自らに有利なように逆転すると共に、粘り強い活動の結果、積極行動主義をとる先住民たちの国際的なネットワークに連なることにも成功し、先住民性に関する諸原則に則りながら、文化を再発明するためのプログラムを練り上げている。2008年の国会決議によって、日本の先住民として認定された後も、アイヌはナショナリズムや内向的姿勢に陥ることなく、他の多くの先住民たちに倣いながら、人新世(anthropocène)という危機的な時代の最中、利潤追求の結果抑制が効かなくなったまま、地球規模で推し進められる経済的発展に脅かされた環境の守護者として、その地位を確立している。本調査における分析により、自身が置かれた不利な状況にも関わらず、今日も依然として強い影響を残す社会文化的な変容に対応し、対処していくため、これまでアイヌが練り上げてきた、今日の状況にも適う、極めて現代的な性格を有する彼らの思考とその戦略について、新たな理解がもたらされるであろう。
Kinnunen, V. V. (Vili-Valtteri), and J. (Jussi) Laitinen. "Yhteisopettajuus:kaksin aina kaunihimpi?" Bachelor's thesis, University of Oulu, 2018. http://urn.fi/URN:NBN:fi:oulu-201805091674.
Full textChartier-Kastler, Bénédicte. "La nephrotoxicité des AINS." Paris 5, 1988. http://www.theses.fr/1988PA05P170.
Full textGARRIGOU, FAGES LAURENCE, and VALERIE FARAUT. "Ventres aigus chez les plus de soixante ans." Bordeaux 2, 1988. http://www.theses.fr/1988BOR25145.
Full textAYMARD, FRANCINE. "L'ivresse aigue au service d'urgences de l'hopital saint joseph : a propos de 741 cas en 1985 et de 1073 cas en 1989." Lyon 1, 1990. http://www.theses.fr/1990LYO1M335.
Full textIMPERATORI, JOEL. "Narcan dans les intoxications ethyliques graves." Aix-Marseille 2, 1988. http://www.theses.fr/1988AIX20141.
Full textBARDIAUX, LAURENT. "Les urgences abdominales dans le service de chirurgie viscerale du c. H. U. De besancon en 1991 : a propos de 454 cas." Besançon, 1993. http://www.theses.fr/1993BESA3015.
Full textMedraj, Mamoun. "Phase equilibria in the AIN-AIO-YO system : utility in AIN processing." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=38082.
Full textBinary diagrams of A2O3-Y2O3, AlN-Al2O3, and AlN-Y2O3 were thermodynamically modeled in this work. The obtained Gibbs free energies of the components, stoichiometric phases and solution parameters were used for the calculation of the isothermal sections and liquidus surface of the AlN-Al2O 3-Y2O3 system. Phase evolutions, melting and solidifications in the Al2O3-Y2O3 phase diagram were investigated using x-ray diffraction and in situ high temperature neutron diffractometry. The phase diagram of AlN-Y2O 3 system was established and verified experimentally. The predicted ternary phase diagram for AlN-Al2O3-Y2O 3 was also verified experimentally using in situ high temperature neutron diffractometry and it has been constructed for the first time in this work.
A self-consistent thermodynamic database including all the phases in the AlN-Al2O3-Y2O3 system was developed during the course of this project. This database was used to explain the experimental results of AlN sintering. It has been found that the samples with high densities had lower liquid formation temperatures, and low thermal conductivity was related to the residual Al2O3 and high YAP (Al2O3.Y2O3) content.
Martin, Goubier Maryse. "Climat et aquaculture : application aux étangs de la Dombes." Lyon 3, 1991. http://www.theses.fr/1991LYO31015.
Full textThis work is a study of la dombes'climate and its influence on pond water management, in this french region covered with 10 000 ha of traditionnally managed fish ponds. First, a detailed survey of the regional climate is reported on, based upon observations and measurements from the national weather service. Different parameters are analysed : - rainfall and its geographical distribution, a very important parameter for pond fill up and water level maintenance during summer; - air temperature, which governs the water temperature, and determines the fish species which can be raised and the most favorable rearing periods in the year. - other climatic descriptors : solar radiation, wind characteristics and related processes like evaporation, factors affecting directly or indirectly the thermal structure of water bodies. These "local climate" features are then replaced in the pattern of low-level circulation, which governs climate characteristics in the temperate zone, and therefore in france. Weather successions in la dombes appear to be ordered by general airmass dynamics, and especially by the polar mobile highs. The latter are responsible at the same time for pressure variations, wind, temperature, cloudiness, rain, in brief for permanent weather variability. The local factors in the resulting weather is only responsible for some increase or reduction in
Karam, Simon. "Manifestations psychiatriques du lupus erythemateux aigu dissemine." Lille 2, 1992. http://www.theses.fr/1992LIL2M312.
Full textNavarri, Pascale. "L'investigation psychosomatique du lupus erythemateux aigu dissemine." Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20955.
Full textGRE, JEROME. "Le lupus erythemateux dissemine familial : a partir de deux observations cliniques." Bordeaux 2, 1988. http://www.theses.fr/1988BOR25151.
Full textLAURENTI, DANIELLE MARIE PAULINE. "Moments feconds : nevrose ou psychose ?" Aix-Marseille 2, 1993. http://www.theses.fr/1993AIX20154.
Full textRoth, Gwenaël. "Syndromes coronariens aigus en Guadeloupe : caractéristiques et prise en charge hospitalière de 91 cas consécutifs." Antilles-Guyane, 2007. http://www.theses.fr/2007AGUY0177.
Full textGuadeloupe is a Frençh island located in the west Indies where, accordlng to different studies, 23 to 32 % of the population suffers from hypertenslon, 6. 6 % from diabetes and 16 to 27% from obesity. However. Epidermiology of acute coronary syndromes and care of patient in Guadeloupe have not been described specifically yet. This retrospective study was carried out on cohort of 91 patients born ln the Caribbean and living in the Guadeloupe archipelago, hospitalized at the University Hospital of Pointe-à-Pitre for acute coronary syndrome (ACS) between october 2004 and october 2005. Risk factors (RF) are over-represented with overweight affecting 65%, high blood presure 63% dyslipidemia 50% and diabetes 33% of the poputation, respectively. On the other hand smoking rate is Iow, at 20% of the population. Lack of information among this population results in late initial care. Nevertheless, compIication and death rates remain within published standards. This study couId not be as complete as expected owing to its retrospective character and to the lack of uniform information available in the medical files. However, we have been able to demonstrate the prevalance or RF in patients suffering from ACS showing the importance of improving prevention it this high risk population
Ruiz, Soriano Joan. "Mecanisme Antioxidant de Compostos Antiinflamatoris no esteroïdals (AINE)." Doctoral thesis, Universitat de Barcelona, 2004. http://hdl.handle.net/10803/1804.
Full textL'estudi d'aquests mecanismes d'inhibició s'ha realitzat utilitzant mètodes indirectes de relació quantitativa estructura-activitat (QSAR) i mètodes directes per tècniques de docking (anclatge) i de molecular modeling (modelatge molecular) dels complexos [inhibidor-COX].
En els mètodes indirectes, en una primera etapa s'ha optimitzat la estructura molecular dels inhibidors per mètodes semiempírics MNDO, AM1, PM3 i mètodes ab inito (3-21G) i posteriorment a través de l'anàlisis conformacional dels grups químics que permeten la lliure rotació molecular s'han obtingut les conformacions de mínima energia. S'ha seleccionat la conformació possiblement bioactiva per superposició (fitting) amb el substracte àcid araquidònic. Finalment s'han calculat diferents propietats electròniques,de lipofilia i estèriques per les sèries de derivats en la conformació bioactiva. Com paràmetres electrònics s'han calculat les càrregues electròniques i la densitat electrònica en determinats àtoms i fragments moleculars, també s'ha calculat el moment dipolar "mi", les energies en els orbitals frontera HOMO-LUMO. Per avaluar la lipofilia s'ha calculat el ClogP. També s'ha representat el PEM i els mapes d'interacció GRID per diversos grups químics, així com les propietats de solvatació amb el programa AMSOL.
Com a resultat les activitats antiinflamatòries in vivo (disminució del volum de l'edema provocat per injecció de carragenina) i in vitro (IC50 ) per la inhibició de la COX correlacionen quantitativament amb la densitat electrònica "pi" dels anells aromàtics, així com amb el moment dipolar, indicant l'existència d'un primer procés de fixació a l'enzim a través del grup carboxílic i una posterior transferència electrònica entre el segon anell aromàtic i el receptor. Aquesta correlació ha estat corroborada amb la representació dels mapes de PEM, que diferencien a més el mecanisme d'inhibició temps dependent dels temps independent. Així els inhibidors temps dependents: àc. meclofenàmic, indometacina, diclofenac i flurbiprofèn entre altres presenten una distribució del PEM amb forma cònica sobre el primer anell aromàtic i amb el vèrtex localitzat en el grup carboxílic, mentre que els inhibidors temps independents: amfenac, fenclofenac, àc. mefenàmic, àc. flufenàmic, ibuprofèn i naxoprèn entre altres localitzen el PEM en el 1r. i 2n anells aromàtics.
Els mètodes directes de docking i molecular modelling també corroboren i diferencien aquests dos mecanismes d'inhibició: els inhibidors temps dependents estabilitzen la presència d'una xarxa de molècules d'aigua que possibilita el tancament del locus de la COX entre els residus Arg120 i Tyr355 afavorint la formació de ponts d'hidrogen entre els residus Glu524-Arg513 i Arg120-Tyr355, fet que explicaria que aquests compostos temps dependents romanguessin més temps en el centre actiu de l'enzim podent establir així unions complementàries amb residus específics (Val523, Tyr385).
Respecte al mecanisme antioxidant dels fenols i derivats del BHT s'ha verificant que aquests inhibidors actuarien mitjançant un mecanisme de captació de radicals, en aquest procés de neutralització intervindria el radical fenòxid, els derivats més actius tindrien més facilitat per formar aquest radical, el qual seria més estable que en els derivats pocs actius, així l'antiinflamatòria correlaciona amb l'entalpia de reacció delta-Hr per la formació del radical fenòxid a l'igual que la densitat electrònica en el punt crític de l'enllaç O-H. Les propietats de lipofilia també serien un factor determinant per la inhibició dual dels enzims COX i 5-LOX, tenint els compostos més actius un elevat ClogP, la inhibició de la COX2 humana pels fenols ha estat verificada pels mètodes de docking interaccionant el grup fenòlicamb la Ser530 i l'àrea hidrofòbica es localitzaria en un locus específic de l'enzim. En la inhibició de la 5-LOX seria important la interacció dels inhibidors amb l'àtom de ferro de l'enzim que resultaria reduït de d'estat fèrric a ferròs, fet que explicaria la capacitat d'inhibició dual COX i 5-LOX per aquests derivats. Finalment els dos models d'inhibició han estat validats amb sèries de compostos COX selectius i 5-LOX selectius.
Larigauderie, Laurence. "Etat confusionnel aigu chez la personne âgée hospitalisée." Bordeaux 2, 1996. http://www.theses.fr/1996BOR2M013.
Full textPaillet, Karine. "Le vertige aigu chez l'adulte et son traitement." Bordeaux 2, 1995. http://www.theses.fr/1995BOR2P052.
Full textDOISE, CHRISTINE. "Acidose metabolique au cours de l'asthme aigu grave." Lille 2, 1993. http://www.theses.fr/1993LIL2M367.
Full textRaffi, Dan Robert Jean-Michel. "Mopral et les AINS stratégie marketing en 2002 /." [S.l.] : [s.n.], 2006. http://theses.univ-nantes.fr/thesemed/PHraffi.pdf.
Full textJouan, Dominique. "Les manifestations ophtalmologiques du lupus érhytémateux aigu disséminé." Caen, 1990. http://www.theses.fr/1990CAEN3075.
Full textAmstatt, Benoît. "Croissance d’hétérostructures non-polaires de nitrure de Gallium plan m sur nitrure d’aluminium plan m sur carbure de silicium 6h plan m." Université Joseph Fourier (Grenoble), 2008. http://www.theses.fr/2008GRE10021.
Full textThis work reports on the growth and the structural and optical properties of non-polar m-plane GaN/AlN heterostructures deposited on m-plane 6H-SiC by Plasma Assisted Molecular Beam Epitaxy. We first studied AlN and GaN thick layers. The optimal growth conditions were achieved in metal-rich conditions. They both exhibit anisotropic surface morphology: stripped for AlN and slatted for GaN. Next, we studied the growth of GaN/AlN heterostructures. GaN quantum wells are obtained in N-rich conditions whereas GaN quantum wires or quantum dots are formed in Ga rich conditions by Stranski-Krastanow growth mode. The shape of these GaN nanostructures is depending on the strain state of the AlN buffer layer. Optical studies revealed a strong reduction of the internal electric field in m-plane GaN/AlN heterostructures. Finally, we focused on the shape evolution of wires and dots with the amount of GaN deposited. We demonstrated the existence of a dots to wires transition. It takes place above a critical size that can be controlled by the amount of GaN deposited or by the growth of superlattices
Puel, Vincent. "Echocardiographie et doppler a la phase initiale du rhumatisme articulaire aigu." Bordeaux 2, 1992. http://www.theses.fr/1992BOR23001.
Full textRICHARD, PASCAL. "Complications non traumatiques de l'ivresse ethylique de l'adulte : a propos de 297 cas." Angers, 1992. http://www.theses.fr/1992ANGE1039.
Full textJanah, Taoufik. "Sur quelques modes de réponses psychologiques et psychopathologiques à la maladie organique chronique chez l'adulte : cas du lupus érythémateux disséminé systémique (la maladie lupique) : esquisse d'une approche somatopsychologique." Paris 13, 1993. http://www.theses.fr/1993PA131032.
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