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Dissertations / Theses on the topic 'Airway epithelium'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 July 2024

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1

Shebani, Eyman. "Ultrastructural Studies of the Airway Epithelium in Airway Diseases." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6632.

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2

Stevens, Paul. "Intrinsic differences of the airway epithelium in childhood allergic asthma." University of Western Australia. School of Paediatrics and Child Health, 2009. http://theses.library.uwa.edu.au/adt-WU2010.0022.

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[Truncated abstract] Asthma affects millions of people worldwide and places a substantial burden on the healthcare system. Despite advances in our understanding of disease mechanisms and the role of respiratory viruses in asthma exacerbations, there is little known regarding the role of the epithelium in commonly observed structural changes in the airway wall. The epithelium of the airways provides an essential protective barrier between the environment and underlying structures and is responsible for the secretion of diverse compounds. Since it is likely that dysregulated epithelial character

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3

Scull, Margaret Adele Pickles Raymond J. "Myxovirus interaction with the human airway epithelium." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2009. http://dc.lib.unc.edu/u?/etd,2848.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2009.<br>Title from electronic title page (viewed Jun. 4, 2010). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Microbiology and Immunology." Discipline: Microbiology and Immunology; Department/School: Medicine.

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4

Wang, Jiahua. "The role of airway epithelium in airway inflammation and effect of corticosteroids." Thesis, Queen Mary, University of London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300175.

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5

Rowley, Jessica. "The interaction of Aspergillus fumigatus with the respiratory epithelium." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/the-interaction-of-aspergillus-fumigatus-with-the-respiratory-epithelium(0fc10449-977d-4f14-a169-172e8204fee4).html.

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Aspergillus fumigatus is a filamentous fungus and the main pathogen responsible for the often fatal respiratory condition, aspergillosis. Airway epithelial cells (AECs) are likely to be the first line of host defence that come into contact with the inhaled conidia of A. fumigatus. Recent evidence strongly suggests that the response of the airway epithelium to inhaled pathogens is pivotal in orchestrating immune responses by inducing phagocytic-like reactions and the secretion of inflammatory cytokines and antimicrobial peptides. However, the majority of previous work investigating A. fumigatus

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6

Fox, Emma. "Systemic delivery of DNA to the airway epithelium." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409742.

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7

Leahy, Rachel A. "Signal Transduction and Cellular Differentiation in Airway Epithelium." Kent State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=kent1352673026.

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8

FORTNER, CHRISTOPHER NEIL. "EPITHELIUM-DEPENDENT RELAXATION OF AIRWAY SMOOTH MUSCLE IS LINKED TO EPITHELIAL CHLORIDE CURRENTS." University of Cincinnati / OhioLINK, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=ucin983467525.

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9

Williams, M. T. S. "Impact of different CFTR Mutations on Airway Epithelium Function." Thesis, Queen's University Belfast, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527902.

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10

Jing, Yi. "Epithelial mechanisms in airway responses induced by hyperosmolarity." Morgantown, W. Va. : [West Virginia University Libraries], 2007. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=5054.

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Thesis (Ph. D.)--West Virginia University, 2007.<br>Title from document title page. Document formatted into pages; contains xiv, 155 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references.

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11

Nilsson, Harriet. "Studies of Tight Junctions and Airway Surface Liquid in Airway Epithelium with Relevance to Cystic Fibrosis." Doctoral thesis, Uppsala universitet, Institutionen för medicinsk cellbiologi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-99411.

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Cystic fibrosis (CF) is a multi-organ autosomal recessive disease of fluid-transporting epithelia, due to a mutation in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is a cAMP-regulated Cl-channel involved in various regulatory processes. Salt and water transport depend on CFTR and the epithelial sodium channel (ENaC), operating in concert with the paracellular pathway through the tight junctions (TJ). The ionic composition of the ASL has been assumed to be altered in CF, resulting in a fatal accumulation of viscous mucus in the airways. ASL s

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12

Armit, Christopher James. "p53 and responses to DNA damage in small airway epithelium." Thesis, University of Edinburgh, 2001. http://hdl.handle.net/1842/27777.

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The effects of p53 were investigated in a mouse model of acute lung injury and in short-term primary cultures of isolated Clara cells. Gene targeted mice, germline deficient in p53, were exposed to γ-irradiation and compared to wild type controls. The in vivo response was to DNA damage was characterised in terms of growth arrest, apoptosis, morphology, and gene expression. An acute stress response was observed in vivo, and localised to a subpopulation of the lung epithelium, the bronchiolar cells. p53 was stabilised in this population and was associated with transcriptional induction of Bax, b

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13

Stefanowicz, Dorota. "Profiling the epigenetic landscape of the airway epithelium in asthma." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/47071.

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The airway epithelium is the interface between the environment and the submucosa of the lung and thus is the first line of defense against inhaled exogenous agents. In addition to maintaining a structural barrier through homeostasis and repair, the airway epithelium is involved in co-ordination of the mucosal immune response to the inhaled environment. In asthma it is now understood that the airway epithelium is abnormal with dysregulation of genes integral to differentiation, proliferation, and inflammation. Alteration of the chromatin architecture through epigenetic modifications includin

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14

McGrogan, Ita. "Release and actions of prostaglandin E¦2 from canine airway epithelium." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0003/NQ42751.pdf.

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15

Amineh, Abbadi. "Hyaluronan Rafts on Airway Epithelial Cells." Cleveland State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=csu1407316041.

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16

Kao, Cheng-Yuan. "Molecular characterization of human airway epithelium innate immunity by IL-17 regulation /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2005. http://uclibs.org/PID/11984.

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17

Xenariou, Stefania. "Magnetofection and sonoporation to enhance non-viral gene transfer to airway epithelium." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433595.

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18

Johnston, Richard A. "Characterization of the airway epithelial bioelectric mechanisms associated with the effects of epithelium-derived relaxing factor in guinea-pig isolated trachea." Morgantown, W. Va. : [West Virginia University Libraries], 2000. http://etd.wvu.edu/templates/showETD.cfm?recnum=1776.

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Thesis (Ph. D.)--West Virginia University, 2000.<br>Title from document title page. Document formatted into pages; contains ix, 135 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 127-135).

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19

Fischer, Anthony John. "Augmenting antiviral host defense in the respiratory epithelium." Diss., University of Iowa, 2009. https://ir.uiowa.edu/etd/500.

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The airway epithelium has many roles in innate immunity including detection of pathogens and transmitting danger signals to other cell types. However, its role as a primary defender against infection is not well recognized. We have investigated methods of augmenting antiviral immunity by application of agents that stimulate viral killing, either in the extracellular space or within the cytoplasm. A recently described property of airway epithelial cells is direct oxidative killing of bacteria through the coordination of Duox and lactoperoxidase enzymes. We have exploited this property by supple

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20

Ang, Sherlynn. "Characterising and assessing the baseline functionality of the airway epithelium in preterm infants." Thesis, Ang, Sherlynn (2017) Characterising and assessing the baseline functionality of the airway epithelium in preterm infants. Honours thesis, Murdoch University, 2017. https://researchrepository.murdoch.edu.au/id/eprint/39878/.

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Introduction & Aims: Preterm birth rates have risen to over 8% in Australia. The lungs are one of the last organs to develop and therefore, the preterm lung is immature at birth. As effects of premature birth on airway cell function are unknown, we investigated whether preterm nasal epithelial cells (NECs) are inherently different to cells of full-term born infants. Methods: The NECs were obtained via brushing nine preterm born infants (5 males, average gestational age at birth 26.6 ± 2.4 weeks) aged 1.7 years corrected age and nine full-term born infants (5 males) aged 2.3 ± 0.2 years

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21

Relova, Anne-Jacqueline. "Mechanisms for and Effects of Airway Epithelial Damage in Asthma." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5312-0/.

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22

Shum, Bennett Oh Vic St Vincent's Clinical School UNSW. "Regulation of allergic asthma by fatty acid-binding proteins." Awarded by:University of New South Wales. St. Vincent's Clinical School, 2007. http://handle.unsw.edu.au/1959.4/27002.

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Fatty acid-binding proteins are small intracellular proteins with poorly defined functions in intracellular fatty acid transport. The adipocyte fatty acid-binding protein aP2 regulates systemic glucose and lipid metabolism. Using Affymetrix microarrays, we found that aP2, in addition to being abundantly expressed by adipocytes, is also expressed by airway epithelial cells. aP2 expression was markedly increased following stimulation of epithelial cells with the Th2 cytokines IL-4 and IL-13, and downregulated by the Th1 cytokine IFN-gamma. Regulation of aP2 mRNA expression by Th2 cytokines was d

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23

Millar, Büchner Pamela [Verfasser], and Marcus A. [Akademischer Betreuer] Mall. "Role of the epithelial Cl- channel SLC26A9 in the murine airway epithelium / Pamela Millar Büchner ; Betreuer: Marcus A. Mall." Heidelberg : Universitätsbibliothek Heidelberg, 2021. http://d-nb.info/1237270790/34.

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24

Farnell, Edward John. "Cloning, disruption and characterisation of Aspergillus fumigatus allergen proteases and their effect on airway epithelial cells." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/cloning-disruption-and-characterisation-of-aspergillus-fumigatus-allergen-proteases-and-their-effect-on-airway-epithelial-cells(cee1b5be-76cd-477c-bdb8-bdaa945d4e02).html.

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Allergen proteases from a number sources including the filamentous fungus A. fumigatus, are thought to be important in the development of severe asthma through protease dependent interactions with the respiratory epithelium. The first aim of the thesis was to determine the effect of a variety of growth substrates on the secretion of proteases from different strains of A. fumigatus. The second aim was to investigate the effects of recombinant allergen proteases Asp f 5 and Asp f 13 expressed in the P. pastoris protein expression system and crude A. fumigatus culture supernatants on airway epith

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25

Leir, Shih-Hsing. "ICAM-1 and CD44 expression in human bronchial epithelium and the role of CD44 isoforms in cell adhesion, migration, and repair." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323933.

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26

Nakatsuka, Yoshinari. "Pulmonary Regnase-1 orchestrates the interplay of epithelium and adaptive immune systems to protect against pneumonia." Kyoto University, 2018. http://hdl.handle.net/2433/235979.

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27

Nordenhäll, Charlotta. "Airway effects of diesel exhaust in healthy and asthmatic subjects." Doctoral thesis, Umeå universitet, Lungmedicin, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-96901.

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Several epidemiological studies have revealed an association between particulate matter (PM) pollution and various health effects. Importantly, there is evidence to suggest that individuals with pre-existing respiratory disease, such as asthma, are more sensitive to elevated ground levels of particulate matter as compared to healthy subjects. Among the various sources of PM pollution, diesel powered vehicles have been identified as important contributors. The aim of this thesis was to investigate the airway effects of experimental chamber exposure to diesel exhaust (DE) in healthy and asthmati

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28

Wilson, Kirsty. "Modelling the airway epithelium in vitro as a tool for understanding pulmonary innate defence mechanisms." Thesis, University of Sheffield, 2015. http://etheses.whiterose.ac.uk/13496/.

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The airway epithelium forms a continuous barrier from the nose to the alveoli and serves a variety of functions. Multiple functionally distinct cell types are involved in these processes. The innate defence functions require a patent airway epithelium, with infections often associated with epithelial defects and phenotypic alterations that are themselves associated with multiple lung diseases. Non-typeable Haemophilus influenzae (NTHi) and respiratory syncytial virus (RSV) are frequently identified in the airways in a range of respiratory diseases These pathogens often trigger exacerbations an

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29

Yahaya, Badrul H. "Analysis of time-dependent transcriptomic and phenotypic changes associated with repair and regeneration in the airway epithelium." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4800.

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The airway epithelium demonstates the ability to quickly repair following physical injury. The morphologic features of this dynamic repair process have been well characterised at the anatomic and cellular level using a number of animal model systems and these studies have provided a solid foundation upon which our understanding of normal repair is build. With the advent of molecular and bioinformatic tools and resources the opportunity exists to extend the value of these models in defining the molecular pathways and interactions that underlay the normal repair process. This thesis represents a

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30

Murphy, Desmond Michael. "The potential role of the airway epithelium and novel therapeutic strategies in post-transplant obliterative bronchiolitis." Thesis, University of Newcastle Upon Tyne, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485564.

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Long-term survival of lung transplant recipients is limited by development of chronic allograft rejection, manifesting as bronchiolitis obliterans syndrome (BOS), and affecting over 50% of patients surviving more than 5 years post transplant. Unfortunately, current strategies in the management of BOS have had limited impact on its development and progression. The histological lesion of BOS, obliterative bronchiolitis (OB), is characterised by bronchiolar epithelial activation, airway leukocyte infiltration and fibro-proliferation, leading to obliteration of bronchioles through deposition of co

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31

Tcacencu, Ion. "Regenerative medicine of the airway cartilage : a morphological and immunohistochemical study with focus on cricoid cartilage defects treated with BMP 2 /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-345-0/.

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32

Ayers, M. "The effect of tobacco smoke on renewal mechanisms in airway epithelium and changes induced by N-acetylcysteine." Thesis, Imperial College London, 1988. http://hdl.handle.net/10044/1/46947.

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33

Tully, Jane Elizabeth. "Classical and alternative nuclear factor-kappaB in epithelium: impacts in allergic airway disease and avenues for redox regulation." ScholarWorks @ UVM, 2014. http://scholarworks.uvm.edu/graddis/500.

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Nuclear Factor kappaB (NF-êB) is a transcription factor whose activation is increased in settings of allergic asthma. At least two parallel NF-êB pathways exist: the classical pathway, which plays a role in inflammation and cell survival, and the alternative pathway, which regulates lymphoid cell development and organogenesis. The classical NF-êB pathway regulates inflammatory responses derived from lung epithelial cells; however, the role of the alternative pathway in lung epithelial cells remains unclear. We demonstrate that both classical and alternative NF-êB are activated in lung epith

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34

Moisey, Elizabeth Jane. "The innate immune response of large and small airway epithelium to respiratory pathogens in chronic obstructive pulmonary disease." Thesis, University of Newcastle upon Tyne, 2016. http://hdl.handle.net/10443/3443.

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Chronic obstructive pulmonary disease (COPD) is a smoking‐related inflammatory lung disease in which small airways remodelling contributes to loss of lung function. Bacterial colonisation in clinically stable COPD patients may play a role in persisting inflammation despite smoking cessation. I propose that the innate immune response from small airway epithelium is more potent than from large airway epithelium, an effect which may be dampened by cigarette smoke, favouring persistent bacterial colonisation in COPD. Nineteen patients with COPD and eleven healthy volunteers were recruited for inve

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35

Alonso, Pedro A. "Regional differences in the response of the hamster airway epithelium to elastase: In vivo and In vitro studies." Thesis, Boston University, 1994. https://hdl.handle.net/2144/37997.

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Thesis (Ph.D.)--Boston University<br>PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>The hamster model of experimental chronic bronchitis comprises a persistent increase in the proportion of bronchial granulated secretory cells after a single intratracheal instillation of elastase. This granu

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36

Shao, Xingguo. "Identification of a Tans-differentiation factor, Rad, a small Ras-like GTP-binding protein, in the regulation of epithelial cell differentiation in human airway epithelium /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2003. http://uclibs.org/PID/11984.

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37

Acciani, Thomas H. "EGF Receptor Signaling and Diesel Exhaust Particle Exposure in Asthma Pathogenesis." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1428068959.

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38

Campbell, Sara J. "Mechanisms of Moraxella catarrhalis Induced Immune Signaling in the Pulmonary Epithelium." University of Toledo Health Science Campus / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=mco1268141520.

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39

Bhandari, Anita [Verfasser]. "Impact of cigarette smoke exposure on the airway epithelium of Drosophila melanogaster to model COPD-like phenotypes / Anita Bhandari." Kiel : Universitätsbibliothek Kiel, 2019. http://d-nb.info/1181096731/34.

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40

Perng, Diahn-Warng. "The proinflammatory actions of mast cell tryptase and agonists of protease activated receptor 2 on the human airway epithelium." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327262.

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41

Machala, Anna. "Rhinovirus infection of the human airway epithelium : in vitro characterization of viral replication, inflammatory response, and immunemodulating effects of echinacea." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/31854.

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Rhinoviruses (RVs) are the leading cause of upper-respiratory tract infections in humans. To date relatively little is known about the mechanism of RV infection and no cure or prevention exists. Mounting evidence shows that RV replicates very little in its host airway epithelial cells leading researchers to hypothesize that the illness associated with RV infection is the result of the host's immune response, but not necessarily RV replication. This study characterized RV infection in vitro in terms of viral replication, viral RNA, and pro-inflammatory cytokine/chemokine secretion over t

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42

Larson, Shawnessy Dawn. "The distribution of the neural components within the airway epithelium in healthy animals and animals exposed to allergens and/or ozone /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2003. http://uclibs.org/PID/11984.

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43

CARBONE, ANNALUCIA. "Isolation of human amniotic stem cells from term placenta and their in vitro differentation in airway epithelium to correct CF phenotype." Doctoral thesis, Università degli Studi di Cagliari, 2012. http://hdl.handle.net/11584/266062.

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Cystic fibrosis (CF) is a lethal autosomal recessive disorder due to mutations in the CF transmembrane conductance regulator (CFTR) gene, a cAMP-dependent chloride channel expressed on the apical side of epithelial cells. Although CF involves many organs with secretory/absorptive properties, including the liver, the main cause of morbidity and mortality is a chronic inflammatory lung disease. Because of its monogenic nature, and since the lung is easily accessible, CF has been a target disease for gene-based therapeutic intervention; however, this approach has given unsatisfied results in t

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44

Servetnyk, Zhanna. "Functional Aspects of Epithelia in Cystic Fibrosis and Asthma." Doctoral thesis, Uppsala University, Department of Medical Cell Biology, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8905.

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<p>The cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP activated chloride channel in the apical membrane of epithelial cells, is defective in patients with cystic fibrosis (CF). Research efforts are focused on chloride channel function in order to find a cure for the disease.</p><p>Genistein increased chloride transport in normal and delF508-CFTR cultured airway epithelial cells without cAMP stimulation. Prior pretreatment with phenylbutyrate did not affect the rate of the genistein-stimulated chloride efflux in these cells.</p><p>S-nitrosoglutathione is an endogenous bronch

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45

Pandey, Sumali. "Lung mucosal response to repeated inhalational insults with immunomodulatory agents in a murine model of fungal asthma| Airway epithelium takes the center stage." Thesis, North Dakota State University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3603972.

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<p> Asthma is a debilitating disease of the lungs affecting 235 million people worldwide. Fungus-associated asthma leads to a particularly severe type of disease, and exposure to environmental fungi and their products is unavoidable due to the ubiquitous nature of fungal species. Besides being allergenic, fungi are opportunistic pathogens, and anti-fungal and/or allergic pathways may be modified through repeated inhalation of immunomodulatory agents, affecting the outcome of fungus-induced asthma. </p><p> Our aim in this project was to investigate the extent to which repeated inhalation of

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Pandey, Sumali. "Lung Mucosal Response to Repeated Inhalational Insults with Immunomodulatory Agents in a Murine Model of Fungal Asthma: Airway Epithelium Takes the Center Stage." Diss., North Dakota State University, 2013. https://hdl.handle.net/10365/26759.

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Asthma is a debilitating disease of the lungs affecting 235 million people worldwide. Fungus-associated asthma leads to a particularly severe type of disease, and exposure to environmental fungi and their products is unavoidable due to the ubiquitous nature of fungal species. Besides being allergenic, fungi are opportunistic pathogens, and anti-fungal and/or allergic pathways may be modified through repeated inhalation of immunomodulatory agents, affecting the outcome of fungus-induced asthma. Our aim in this project was to investigate the extent to which repeated inhalation of immunomodulator

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47

Ruiz, Garcia Sandra. "Appréhender l'hétérogénéité cellulaire et la dynamique de différenciation des épithéliums des voies aériennes au moyen de signatures transcriptionnelles sur cellule unique." Thesis, Université Côte d'Azur (ComUE), 2018. http://www.theses.fr/2018AZUR4204/document.

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Les voies aériennes humaines sont bordées d'un épithélium pseudostratifié composé principalement de cellules basales et de cellules pyramidales parmi lesquelles figurent les cellules sécrétrices de mucus et les cellules multiciliées. Toutes ces cellules contribuent à la clairance mucociliaire des voies respiratoires. Cet épithélium se régénère lentement dans des conditions homéostatiques, mais il est capable de se régénérer rapidement après agression grâce à des processus de prolifération, de migration, de polarisation et de différenciation. Chez les patients atteints de maladies respiratoires

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48

Österlund, Camilla. "Activation of lung epithelial cells by group 2 mite allergens." Doctoral thesis, Umeå universitet, Lungmedicin, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-51619.

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Throughout many parts of the world house dust mites (HDM) are considered as a major source of indoor aeroallergens and they are powerful inducers of allergic diseases. Proteolytic HDM allergens are recognised as being able to directly activate respiratory epithelial cells and thereby actively participate in innate immune responses. Although several major HDM allergens lack proteolytic activity, their possible ability to similarly interact with epithelial cells is not known. The overall aim of this thesis was therefore to elucidate if and how major non-proteolytic group 2 allergens from differe

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49

Steiert, Sabrina [Verfasser], Carsten [Akademischer Betreuer] Schmidt-Weber, and Klaus [Akademischer Betreuer] Schümann. "Evaluation of Anti-inflammatory Potential of Tesalin on Airway Epithelium and Innate Immune Effector Cells / Sabrina Steiert. Betreuer: Carsten Schmidt-Weber. Gutachter: Carsten Schmidt-Weber ; Klaus Schümann." München : Universitätsbibliothek der TU München, 2016. http://d-nb.info/1091562113/34.

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50

Ruiz, Garcia Sandra. "Appréhender l'hétérogénéité cellulaire et la dynamique de différenciation des épithéliums des voies aériennes au moyen de signatures transcriptionnelles sur cellule unique." Electronic Thesis or Diss., Université Côte d'Azur (ComUE), 2018. http://www.theses.fr/2018AZUR4204.

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Les voies aériennes humaines sont bordées d'un épithélium pseudostratifié composé principalement de cellules basales et de cellules pyramidales parmi lesquelles figurent les cellules sécrétrices de mucus et les cellules multiciliées. Toutes ces cellules contribuent à la clairance mucociliaire des voies respiratoires. Cet épithélium se régénère lentement dans des conditions homéostatiques, mais il est capable de se régénérer rapidement après agression grâce à des processus de prolifération, de migration, de polarisation et de différenciation. Chez les patients atteints de maladies respiratoires

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