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Journal articles on the topic 'Alanine amino transferase'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

SihamAgmeeWadee and Mohammad Kailed Shindala. "Effect of Antihistamines (Fexofenadineand Chlopheneramine) on activity some hepatical enzymes by using fertilized hens eggs embryos as a model." Tikrit Journal of Pure Science 22, no. 1 (2023): 31–35. http://dx.doi.org/10.25130/tjps.v22i1.606.

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The aim of the present study was to investigate the effect of antihistamines(Chlorpheneramineand Fexofenadine) on (alkaline phosphatase, aspartate amino transpherase and alanine amino transferase) in tissue of fertilized hens eggs embryos as indicator to tissue damage. The injection of fertilized hen's eggs with antihistamines Fexofenadine at 12th day of incubation in doses (0,5,0,1mg/ egginto air sell)after 24 hour of treatment induce significantly decrease in tissues activity of alkaline phosphatase (ALP),aspartate amino transpherase (AST) and alanine amino transferase (ALT) compared with co

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2

Fowomola, M. A., and A. A. Akindahunsi. "EFFECTS OF SAND BOX (Hura crepitans) SEED MEALS ON RATS' LIVER AND SERUM ENZYME LEVELS." Continental J. Biomedical Sciences 4 (June 16, 2010): 50–54. https://doi.org/10.5281/zenodo.820481.

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The effect of <em>Hura crepitans</em> seed flour, incorporated at 10% (w/w) protein on liver and serum acid phosphatase (E.C. 3.1.3.2), alkaline phosphatase (E.C.3.1.3.1), aspartate – amino transferase activity (AST) (E.C.2.6.1.1) and alanine amino transferase activity (ALT) (E.C.2.6.1.2) activities were investigated. Generally, results of the toxicological investigation showed that acid phosphatase (ACP), alkaline phosphatase (ALP), aspartate amino transferase (AST) and alanine amino transferase (ALT) activities of liver and serum of rats fed on defatted cooked diet were not significantly dif

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3

Čobanović, Nikola, Sanja Dj Stanković, Mirjana Dimitrijević, et al. "Identifying Physiological Stress Biomarkers for Prediction of Pork Quality Variation." Animals 10, no. 4 (2020): 614. http://dx.doi.org/10.3390/ani10040614.

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This study assessed the potential use of various physiological stress biomarkers as indicators of carcass and meat quality traits in 240 pigs subjected to the standard marketing conditions and minimal stressful antemortem handling using Pearson correlations. The most important pork quality traits (pH and temperature, water holding capacity, and color) had limited correlations with stress metabolites (lactate, glucose), stress hormones (cortisol, adrenocorticotropic hormone), stress enzymes (creatine kinase, aspartate amino transferase, alanine amino transferase), electrolytes (sodium, chloride

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4

A., Rajeswari. "ENZYMATIC CHANGES DURING LETHAL AND SUBLETHAL EXPOSURES OF GLYPHOSATE (41% SL) ON FRESHWATER FISH CIRRHINUS MRIGALA." International Journal of Zoology and Applied Biosciences 6, no. 5 (2021): 248–55. https://doi.org/10.5281/zenodo.5707245.

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The lethal and sublethal effect of the Glyphosate (41% SL) on certain enzymes in tissue such as AAT (Aspartate Amino Transferase), ALAT (Alanine Amino Transferase), LDH (Lactate Dehydrogenase) and ACP (Acid Phosphatase) of the freshwater fish, Cirrhinus mrigala during and after the cessation of the exposure were observed. Ten fish were exposed chronically to lethal and sublethal concentrations for a period of 4 days were sacrificed and tissues such as brain, gill, liver, kidney and muscle were analysed for biochemical parameters and remaining five fish were maintained in clean well water for a

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5

Al-Rubaee, Eman A., Huda A. Kadum, and Mohammed S. Al-Braich. "Salivary aspartate amino transferase and alanine amino transferase of non-insulin-dependents (Type2) diabetic patients." Journal of the Faculty of Medicine Baghdad 52, no. 2 (2010): 212–14. http://dx.doi.org/10.32007/jfacmedbagdad.5221026.

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6

Canepari, S., V. Carunchio, A. M. Girelli, and A. Messina. "High performance liquid chromatography assay for alanine amino transferase." Chromatographia 32, no. 1-2 (1991): 23–26. http://dx.doi.org/10.1007/bf02262461.

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7

Eraso, A. J., and I. Albesa. "Elevation of alanine amino transferase and aspartate amino transferase produced by pyoverdin, a photolabile pigment ofpseudomonas fluorescens." Natural Toxins 6, no. 2 (1998): 61–65. http://dx.doi.org/10.1002/(sici)1522-7189(199804)6:2<61::aid-nt5>3.0.co;2-#.

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8

Akhter, Nilufa, Noorzahan Begum, and Sultana Ferdousi. "Some Aspects of Liver Function Status in G6PD Deficient Neonates and Its Relationship with G6PD." Journal of Bangladesh Society of Physiologist 7, no. 1 (2012): 36–40. http://dx.doi.org/10.3329/jbsp.v7i1.11158.

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Background: Neonatal jaundice is a common cause of newborn hospital admission. G6PD enzyme defects is one of the factor to develop neonatal hyperbilirubinemia, which may be related to abnormal liver function in this group of neonates.Objective: To observe some aspects of liver function status by measuring serum bilirubin and alanine amino transferase levels in G6PD deficient neonates and also their relationship with erythrocyte G6PD levels.Methods: The study was conducted on 30 male, term neonates with G6PD deficiency in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University

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9

Inyang, Iniobong R., Dudutari E. Patani, and Sylvester C. Izah. "The Effect of 2,4 Dimethylamine salt on the Blood, Liver and Muscle of Oryclotagus Cuniculus." Journal of Plant and Animal Ecology 1, no. 3 (2020): 21–28. http://dx.doi.org/10.14302/issn.2637-6075.jpae-20-3198.

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Aminoforce containing 720g/l of 2,4-dimethylamine salt induced changes on some enzymes and electrolytes in the male Oryclotagus cuniculus (New Zealand rabbit) were assayed. The organisms were exposed to varying sub-lethal concentrations of the toxicant (720g/l). The concentrations were prepared by pipetting 0.4mls, 0.8mls and 0.12mls making it up to 1.5L clean water in a metal container to make 2.0 mgl-1, 4.0 mgl-1 and 6.0 mgl-1. Aspartate amino transferase (AST), Alanine amino transferase (ALT) and Acid phosphatase (ACP) were assayed in the liver and blood. Results showed that aspartate amino

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10

Mohanad Hasan Mahmood Humadi Al-Izzi, Zaid Mohamad Mubarak, and Ismat Jamal Jamil. "Role of Adiponectin Hormone Concentrations and Some Immunological and Biochemical Parameters inAlloxan Induced Diabetic Male Rabbits and Diabetic Treated with Alpha Lipoic Acid and L-Carnitine." Tikrit Journal of Pure Science 22, no. 6 (2023): 46–51. http://dx.doi.org/10.25130/tjps.v22i6.789.

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This study was designed in order to estimate the effect of alloxan induced diabetes mellitus on adiponectin hormone concentration and some immunological and biochemical parameters of male domestic rabbits. The study involved (20) blood samples were divided into 4 groups : group one: adult normal healthy male rabbits as control group, group two: adult male rabbits with alloxan induced diabetes mellitus, group three: adult male rabbits with alloxan induced diabetes mellitus treated with alpha lipoic acid (100 mg/kg), group four: adult male rabbits with alloxan induced diabetes mellitus treated w

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11

Ngozika, B. Okwandu. "Effects of some anti-histamine on erythrocyte aspartate amino transferase and alanine amino transferase activities in Wistar albino rats." Indian Journal of Science and Technology 5, no. 7 (2012): 1–4. http://dx.doi.org/10.17485/ijst/2012/v5i7.8.

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12

Robertson, Lucy J. "Fluctuations in rat liver alanine-amino-transferase activity during experimental nippostrongylosis." Parasitology 98, no. 2 (1989): 301–6. http://dx.doi.org/10.1017/s0031182000062223.

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SUMMARYThe activity of the gluconeogenic enzyme, alanine-amino-transferase (ALT), in a preparation from the liver of rats was studied by means of an in vitro assay throughout the course of a primary infection of Nippostrongylus brasiliensis, established by a subcutaneous injection of approximately 4000 3rd-stage larvae. The activity was measured on days 1–14 p.i. in both uninfected and infected rats and a marked pattern in the enzyme's activity was observed. In infected rats, the activity increased from 1·46±0·19 U/g liver on day 1 p.i. to a peak on day 4 p.i. of 10·75±1·62 U/g liver, then dec

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13

Omar, Raffal A., and M. J. Eesa. "Comparative study for three protocols of general anesthesia in bucks." Iraqi Journal of Veterinary Medicine 41, no. 2 (2018): 15–23. http://dx.doi.org/10.30539/iraqijvm.v41i2.42.

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The aim of this study was to evaluate three regimens in induction and maintenance of general anesthesia in local breed bucks and the investigation of the best protocol of them based on different parameters. Eighteen healthy adult bucks weighing (27.50 ± 0.682 kg), aged (1.989 ± 0.135 years) were used. Animals were divided randomly into three equal groups to undergo pre-experiment preparation. All groups were premedicated intravenously with (0.5 mg/ kg) Diazepam, ten min. Later, the induction for first group was done by Propofol (3 mg/kg B.W), second group was done by Ketamine Hcl (2 mg/kg B.W)

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14

Lawlor, Debbie A., Mark Callaway, Corrie Macdonald-Wallis, et al. "Nonalcoholic Fatty Liver Disease, Liver Fibrosis, and Cardiometabolic Risk Factors in Adolescence: A Cross-Sectional Study of 1874 General Population Adolescents." Journal of Clinical Endocrinology & Metabolism 99, no. 3 (2014): E410—E417. http://dx.doi.org/10.1210/jc.2013-3612.

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Context: The impact of adolescent nonalcoholic fatty liver disease (NAFLD) on health, independent of fat mass, is unclear. Objective: The objective of the study was to determine the independent (of total body fat) association of ultrasound scan (USS)-determined NAFLD with liver fibrosis, insulin resistance, and dyslipidemia among healthy adolescents. Design: This was a cross-sectional analysis in participants from a UK birth cohort. Participants: One thousand eight hundred seventy-four (1059 female) individuals of a mean age of 17.9 years participated in the study. Main Outcomes: USS assessed

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15

Ahmed Mudher AL- khaykanee, AG Hamad, and Soura Alaa Hussein. "A review about liver function tests." GSC Biological and Pharmaceutical Sciences 30, no. 1 (2025): 213–17. https://doi.org/10.30574/gscbps.2025.30.1.0023.

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In general, Tests for liver function in the laboratory are those that help diagnose and treat patients with hepatic dysfunction. The liver is responsible for the metabolism of fats., proteins, and carbohydrates. As biochemical markers of liver dysfunction, a few end products of metabolic pathways and enzymes that are extremely sensitive to abnormalities could be employed. Serum bilirubin, Ceruloplasmin, α-fetoprotein, alkaline phosphatase, 5′ nucleotidase, aspartate amino transferase, alanine amino transferase, and gamma glutamyl transferase are a few of the biological. If a patient has one or

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16

Moon, Hyung-In. "Antidiabetic effects of dendropanoxide from leaves of Dendropanax morbifera Leveille in normal and streptozotocin-induced diabetic rats." Human & Experimental Toxicology 30, no. 8 (2010): 870–75. http://dx.doi.org/10.1177/0960327110382131.

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The present study evaluated the antidiabetic effect of Dendropanoxide (DP) from Dendropanax morbifera Leveille in normal and streptozotocin-induced diabetic rats. DP in the streptozotocin-induced diabetic rats showed significant hypoglycemic activity for 14 days significantly decreased the serum glucose, total cholesterol, triglycerides, urea, uric acid, creatinine, aspartate amino transferase (AST) and alanine amino transferase (ALT) while it increased the serum insulin in diabetic rats but not in normal rats (p < 0.05; at doses of 30, 60 and 100 mg/kg for 14 days). A comparison was made b

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17

Chen, Sheng-Yi, Jui-Hung Shien, and Hong Kean Ooi. "Serum Alpha-fetoprotein in Rabbits Experimentally Infected with Rabbit Haemorrhagic Disease Virus." Acta Veterinaria Brno 78, no. 3 (2009): 477–81. http://dx.doi.org/10.2754/avb200978030477.

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To investigate the change in serum alpha-fetoprotein (AFP) and its correlation with liver enzymes in hepatitis caused by rabbit haemorrhagic disease virus (RHDV), 15-week-old rabbits were experimentally infected with a Taiwan field isolate of the virus. After RHDV inoculation, it was observed that serum AFP increased significantly (p = 0.0082) together with significant elevation in serum aspartate amino transferase (AST), alanine amino transferase (ALT), γ-glutamyl transferase (γ-GT) and alkaline phosphatase (ALP). Rabbits that died tended to have high AFP values prior to death, the mean value

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18

Kumar, Parmod, Raveena Raveena, and Dar Muneed Hamid. "THE REVIEW ARTICLE ON LIVER FUNCTION TEST IN HUMAN BODY." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 07, no. 12 (2023): 1–11. http://dx.doi.org/10.55041/ijsrem27564.

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Laboratory Liver function tests (LFT) may be defined as the tests which are useful in the evaluation and treatment of patients with hepatic dysfunction. Theliver is of vital importance in intermediary metabolism, in the detoxification andin the elimination of toxic substances. The biochemical tests are useful in detecting the presence of liver disease. The test are also cheap, non- invasive and widely available and are of value in directing the use of other diagnostic tests such as liver biopsy and imaging. Some of the biochemical markers such asserum Bilirubin, SGPT or Alanine amino transfera

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19

Utu-Baku, A. B., G. O. Obochi, S. A. Inah, et al. "The Influence of Alcohol Kolanut Constituents on Liver Aspartate Amino Transferase and Alanine Amino Transferase Enzyme Activities on Albino Wistar Rats." International Journal of Biological Chemistry 3, no. 1 (2008): 25–29. http://dx.doi.org/10.3923/ijbc.2009.25.29.

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20

Gül, Abdullah, and Nazım Abdulkadir Kankılıç. "Association of Preoperative De Ritis Ratio (Aspartate Amino Transferase/Alanine Amino Transferase) and Tumour Histology in Patients with Primary Bladder Cancer." Bulletin of Urooncology 19, no. 3 (2020): 136–40. http://dx.doi.org/10.4274/uob.galenos.2020.1375.

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21

Udobre, Aniefiok, Edoho J. Edoho, Olorunfemi Eseyin, and Emmanuel I. Etim. "Effect of Artemisinin with Folic Acid on the Activities of Aspartate Amino Transferase, Alanine Amino Transferase and Alkaline Phosphatase in Rat." Asian Journal of Biochemistry 4, no. 2 (2009): 55–59. http://dx.doi.org/10.3923/ajb.2009.55.59.

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22

Goel, Ruchika, Debashish Danda, CE Eapen, and Sathish Kumar. "O10 Serum alanine amino transferase—a disease activity marker in inflammatory myositis?" Indian Journal of Rheumatology 6, no. 3 (2011): S3. http://dx.doi.org/10.1016/s0973-3698(11)60099-x.

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23

Nweke-okorocha, G. O., C. A. Chineke, and C. O. Joachim. "Effects of sex, polydactylism and rearing systems on serum biochemical indices of Fulani ecotype chickens in Southwestern Nigeria." Nigerian Journal of Animal Production 47, no. 1 (2020): 24–32. http://dx.doi.org/10.51791/njap.v47i1.175.

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An experiment was conducted to determine the effects of sex, polydactylism and rearing systems on blood serum biochemical indices of 30 Fulani ecotype chickens selected at random from 90 Fulani ecotype chickens raised under intensive management systems (deep litter and caged) for 16 weeks. Blood samples were collected from the birds at 11th and 16thweek was used for biochemical analyses. The parameters measured were Cholesterol, Total protein (TP), albumin (ALB), globulin (GB), aspartate amino transferase (AST), alanine amino transferase (ALT) and alkaline phosphate (ALP). The biochemical para

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24

Dube, Praveen, A. Shwetha, and B. B. Hosetti. "Impact of copper cyanide on the key metabolic enzymes of freshwater fish Catla catla (Hamilton)." Biotehnologija u stocarstvu 30, no. 3 (2014): 499–508. http://dx.doi.org/10.2298/bah1403499d.

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Short term toxicity experiments were conducted to study the effect of metal cyanide complex (copper cyanide) on the key metabolic enzymes viz., lactate dehydrogenase (LDH), succinate dehydrogenase (SDH), glucose-6 phosphate dehydrogenase (G6PDH), aspartate amino transferase (AST) alanine amino transferase (ALT), acid phosphatase (AcP) and alkaline phosphatase (ALP) activity in Catla catla juveniles. A total of 60 fingerlings were (2?0.5 cm; 1.5?0.2 g) exposed to two sublethal concentrations (0.253 and 0.152 mg/L) for a period of 15 days. Copper cyanide had significant (P> 0.05) effect on th

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25

Kort, Sheila A. R., Jeffrey Wickliffe, Arti Shankar, et al. "The Association between Mercury and Lead Exposure and Liver and Kidney Function in Pregnant Surinamese Women Enrolled in the Caribbean Consortium for Research in Environmental and Occupational Health (CCREOH) Environmental Epidemiologic Cohort Study." Toxics 10, no. 10 (2022): 584. http://dx.doi.org/10.3390/toxics10100584.

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Exposure to mercury (Hg) and lead (Pb) may have an effect on pregnant women. We assessed the effect of exposure to mercury and lead on liver and kidney functions in a subcohort of pregnant women who participated in the Caribbean Consortium for Research in Environmental and Occupational Health (CCREOH)—Meki Tamara, study. From 400 women aged 16–46 living in rural, urban, and interior regions of Suriname, we measured blood mercury and blood lead levels. Creatinine, urea, and cystatin C were measured to assess kidney function, and aspartate amino transferase (AST), alanine amino transferase (ALT)

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26

Inyang, I.R., S. Thomas, and E.I. Seiyaboh. "Impact of Fluazifop-p-butyl Exposure on Transferases and Phosphatase in Clarias gariepinus." Greener Journal of Biochemisty and Biotechnology 4, no. 1 (2017): 1–6. https://doi.org/10.15580/GJBB.2017.1.020817020.

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Careless use of pesticide poses animal and human health concerns globally. Pesticide can find their way into food chain, hence the need to examine the effect of fluazifop-P-butyl in <em>Clarias gariepinus. Clarias gariepinus</em> (mean length, 16.04±0.23cm, mean weight 94.05±0.60) were acclimatized to laboratory conditions for seven days and then exposed to varying concentrations of fluazifop-p-butyl in static bioassay for 30 days. Alanine amino transferase (ALT), aspartate amino transferase (AST), and Alkaline transferase (ALP), were evaluated in the liver and plasma.

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27

Pogorelova, Tatyana Nikolaevna, V. O. Gunko, A. A. Mikhelson, A. A. Nikashina, A. F. Mikhelson, and E. Yu Lebedenko. "THE ACTIVITY OF ENZYMES OF AMINO ACID METABOLISM OF THE PLACENTA IN DIFFERENT TERMS OF THE PHYSIOLOGICAL AND COMPLICATED PREGNANCY." Russian Clinical Laboratory Diagnostics 64, no. 5 (2019): 260–64. http://dx.doi.org/10.18821/0869-2084-2019-64-5-260-264.

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The activity of amino acid metabolism enzymes and the content of free amino acids in the placenta during physiological pregnancy and placental insufficiency (PI) were studied using spectrophotometric methods and ion-exchange chromatography. It was found that in PI placental activity of the studied enzymes: alanine-, cysteine-e, tyrosine-, glutamino- transferase, glutathione synthetase, glutamate dehydrogenase decreases at different periods of gestation. The opposite variations occur for aspartataminotranferase and glutaminase. Similar changes are detected for amino acids synthesized or used in

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28

G., Reetha, and Mahesh P. "Prevalence of non-alcoholic fatty liver disease among obese children in North Kerala, India." International Journal of Contemporary Pediatrics 4, no. 3 (2017): 1051. http://dx.doi.org/10.18203/2349-3291.ijcp20171726.

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Background: Obesity and related co-morbidities are increasing at an alarming pace all over the world. Non-alcoholic fatty liver disease (NAFLD) is the asymptomatic involvement of the liver mainly seen in obese individuals. NAFLD can progress to chronic liver disease and has to be identified early. The aims of our study were to determine the prevalence of nonalcoholic fatty liver disease among obese children in our local population. To determine the prevalence of abnormal liver enzymes in obese children.Methods: Cross sectional descriptive study in a tertiary care center among children aged 5-1

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29

A, Rajeswari, and Sunita K. "Enzymatic changes during lethal and sublethal exposures of Glyphosate (41% SL) on freshwater fish Cirrhinus mrigala." International Journal of Zoology and Applied Biosciences 6, no. 5 (2021): 248–55. http://dx.doi.org/10.55126/ijzab.2021.v06.i05.023.

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The lethal and sublethal effect of the Glyphosate (41% SL) on certain enzymes in tissue such as AAT (Aspartate Amino Transferase), ALAT (Alanine Amino Transferase), LDH (Lactate Dehydrogenase) and ACP (Acid Phosphatase) of the freshwater fish, Cirrhinus mrigala during and after the cessation of the exposure were observed. Ten fish were exposed chronically to lethal and sublethal concentrations for a period of 4 days were sacrificed and tissues such as brain, gill, liver, kidney and muscle were analysed for biochemical parameters and remaining five fish were maintained in clean well water for a

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30

Lodhi, Gaurav, Hemant Singh, Kamlesh Pant, and Zeashan Hussain. "Hepatoprotective effects of Calotropis gigantea extract against carbon tetrachloride induced liver injury in rats." Acta Pharmaceutica 59, no. 1 (2009): 89–96. http://dx.doi.org/10.2478/v10007-009-0002-2.

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Hepatoprotective effects ofCalotropis giganteaextract against carbon tetrachloride induced liver injury in ratsEthanolic extract (50 %) of stems ofCalotropis giganteaR. Br. (Asclepiadaceae) at doses of 250 and 500 mg kg-1were studied for hepatoprotective activity in male Wistar rats with liver damage induced using carbon tetrachloride, 2 mL kg-1twice a week. The protective effect ofC. giganteaextract was compared with the standard drug silymarin. Various biochemical parameters such as aspartate amino transferase (AST), alanine amino transferase (ALT), glutathione (GSH), lipid peroxide (LPO), s

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31

Khuda-Bukhsh, Anisur Rahman, Surajit Pathak, Bibhas Guha, et al. "Can Homeopathic Arsenic Remedy Combat Arsenic Poisoning in Humans Exposed to Groundwater Arsenic Contamination?: A Preliminary Report on First Human Trial." Evidence-Based Complementary and Alternative Medicine 2, no. 4 (2005): 537–48. http://dx.doi.org/10.1093/ecam/neh124.

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Groundwater arsenic (As) has affected millions of people globally distributed over 20 countries. In parts of West Bengal (India) and Bangladesh alone, over 100 million people are at risk, but supply of As-free water is grossly inadequate. Attempts to remove As by using orthodox medicines have mostly been unsuccessful. A potentized homeopathic remedy, Arsenicum Album-30, was administered to a group of As affected people and thereafter the As contents in their urine and blood were periodically determined. The activities of various toxicity marker enzymes and compounds in the blood, namely aspart

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32

Moraes, G., A. E. Altran, I. M. Avilez, C. C. Barbosa, and P. M. Bidinotto. "Metabolic adjustments during semi-aestivation of the marble swamp eel (Synbranchus marmoratus, Bloch 1795) - a facultative air breathing fish." Brazilian Journal of Biology 65, no. 2 (2005): 305–12. http://dx.doi.org/10.1590/s1519-69842005000200015.

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Metabolic changes, principally in intermediary metabolism and nitrogen excretion, were investigated in the marble swamp eel (Synbranchus marmoratus) after 15 and 45 days of artificially induced semi-aestivation. Glucose, glycogen, lactate, pyruvate, free amino acids, triglycerides, ammonia, urea, and urate contents were determined in liver, kidney, white muscle, heart, brain, and plasma. Lactate dehydrogenase, glutamate dehydrogenase, malate dehydrogenase, aspartate amino transferase, alanine amino transferase, glutamine synthase, ornithine carbamoyl transferase, and arginase enzymes were assa

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33

Shettima, AY, MA Tijani, K. Mekaron, O. Henry, B. Modu, and Y. Tijjani. "Effect of Methanolic Root Extract of Guiera senegalensis on Some Biochemical and Hematological Parameters in Albino Rats." Pharmaceutical and Chemical Journal 3, no. 2 (2016): 71–78. https://doi.org/10.5281/zenodo.13742785.

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The effect of the administration of methanolic extract of root of <em>Guiera senegalensis</em> on some biochemical and hematological parameters in Wister strain albino rats was investigated. After a period of about 28 days the rats given methanolic root extract of <em>Guiera senegalensis</em> showed no significant increase or decrease in the levels of the biochemical parameters compared to the rats receiving 2 ml of distilled water. That is the extract did not alter the levels of Aspartate transaminase (AST) Alanine transminase (ALT), alkaline phosphatase (ALP), Total protein and albumin. Also

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34

Syafa’ah, Lailis, Zulfatman Zulfatman, Ilham Pakaya, and Merinda Lestandy. "Comparison of Machine Learning Classification Methods in Hepatitis C Virus." Jurnal Online Informatika 6, no. 1 (2021): 73. http://dx.doi.org/10.15575/join.v6i1.719.

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The hepatitis C virus (HCV) is considered a problem to the health of societies are the main. There are around 120-130 million or 3% of the world's total population infected with HCV. Without treatment, most major infectious acute evolve into chronic, followed by diseases liver, such as cirrhosis and cancer liver. The data parameters used in this study included albumin (ALB), bilirubin (BIL), choline esterase (CHE), -glutamyl-transferase (GGT), aspartate amino-transferase (AST), alanine amino-transferase (ALT), cholesterol (CHOL), creatinine (CREA), protein (PROT), and Alkaline phosphatase (ALP

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35

Rosa, Guilherme, Danielli Mello, Rodrigo Gomes de Souza Vale, et al. "Acute effect of concurrent training on hematological and hepatic profile, and muscle injury markers in trained individuals." Retos 69 (July 6, 2025): 690–98. https://doi.org/10.47197/retos.v69.110879.

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Objective: to analyze the acute effect of concurrent training on hematological and hepatic profile, and muscle injury markers in trained individuals. Methodology: 11 trained males (27.0 ± 1.13 years old) were undergone to body composition, muscle strength, cardiorespiratory fitness evaluation and a concurrent training (CT) session. Blood samples of glucose (GLU), total cholesterol (TC), triglycerides (TG), HDL-cholesterol fraction (HDL), LDL-cholesterol fraction (LDL), gamma glutamyl transferase (GGT), alanine amino transferase (ALT), aspartate amino transferase (AST), urea (Ur), bilirubin (Bi

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Taher Al-Isawi, Jameelah Kadhim, and Essam Fadel Al-Jumaily. "Antioxidants and Hepatoprotective Study of a Purified Bauhinia Variegate Leaves and Flowers Against Carbon Tetrachloride-Induced Toxicity in Experimental Rats." Biomedical and Pharmacology Journal 12, no. 1 (2019): 411–22. http://dx.doi.org/10.13005/bpj/1655.

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This study was designed to investigate the hepatoprotective activity and antioxidant enzymes of purified Bauhinia variegate leaves extract and purified flowers extract were administered (200 mg/kg, orally once daily) to reduce the effect of carbon tetrachloride-damage in rat's liver for three weeks. Thereafter, the levels of some serum biochemical factors such as alanine amino transferase, aspartate amino transferase, alkaline phosphatase, and the activity of three different antioxidant enzymes (glutathione, superoxide dismutase, and catalase) were investigated. Liver homogenate can used to es

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Rahman, M. M., and S. Hossain. "Preventive Effect of Ganoderma lucidum on Paracetamol-induced Acute Hepatotoxicity in Rats." Journal of Scientific Research 5, no. 3 (2013): 573–78. http://dx.doi.org/10.3329/jsr.v5i3.14055.

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The effect of Ganoderma lucidum in paracetamol-induced acute hepatotoxicity was investigated on Wistar rats in the present study. Hepatotoxicity was induced by oral administration of paracetamol (500 mg/kg of body weight) for 7 consecutive days. The extent of liver damage was studied by assessing biochemical parameters comprising of plasma aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH), total bilirubin (TB) and total plasma total protein (TP). Oral administration of paracetamol significantly increased the plasma le

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Taha, T. A., E. I. Abdel-Gawad, and M. A. Ayoub. "Monthly variations in some reproductive parameters of Barki and Awassi rams throughout 1 year under subtropical conditions 2. Biochemical and enzymatic properties of seminal plasma." Animal Science 71, no. 2 (2000): 325–32. http://dx.doi.org/10.1017/s135772980005517x.

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AbstractFifteen sexually mature rams, five each of Barki, Awassi (I, imported from Syria) and Awassi (LB, locally born in Egypt) were used to study the biochemical and enzymatic properties of seminal plasma for 12 months. The biochemical analyses of ram seminal plasma indicated that the highest values of total protein, albumin (A), globulin (G), fructose, total lipids and cholesterol were recorded in late summer and early autumn, while A/G and AST/ALT ratios exhibited the lowest values. Lowest values of the same parameters were recorded in winter and late spring, while ratios of A/G and aspart

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Okoye, Ngozi Franca, and Esther Chinyere Nwowo. "The Amelioration of Cyanide Induced Liver Toxicity with Bentonite Using Wistar Rat as Experimental Model." Journal of Advances in Biology & Biotechnology 14, no. 1 (2017): 1–9. https://doi.org/10.9734/JABB/2017/34122.

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<strong>Aim: </strong>The objective of this study was to investigate the ameliorating effect of a natural bentonite found in Nigeria on liver enzymes of Wistar rat fed with cyanide from cassava waste water. The enzymes assayed were alkaline Phosphatase (ALP), alanine amino transferase (ALT) and aspartate amino transferase (AST). <strong>Materials and Methods: </strong>A total of 45 Wistar rats were used. The rats were divided into four groups and a control group. Each group had nine rats including the control. Groups 1, 2, 3, and 4 were given a daily dose of 0.4ml of cassava waste water contai

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H, El Mahdi, Abkhar Z, and Taourirte M. "Valuation of Dates Cores of the Southern Region of Morocco (Zagora): Isolation of Hemicellulose and Their Use in the Development of Biodegradable and Hydrophobic Film." Pharmaceutical and Chemical Journal 3, no. 2 (2016): 143–48. https://doi.org/10.5281/zenodo.13748880.

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The nuclei of dates, from domestic consumption or as waste from the agro-food sector (date tab, syrup, oi etc.) on a small or large scale, or simply contained in the inedible dates, which remain abandoned in palm trees, are a very interesting material for the production of high value added products. They consist mainly of plant cell walls (cellulose, hemicellulose and lignin) that represent 82% to 92% of the initial dried material. The purpose of this study is the extraction of hemicellulose from the nuclei of dates first, then their introduction with the starch in the development of biodegrad

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Ihendu, U., Atansuyi, A. J., and Chineke, C.A. "EFFECT OF SEX AND AGE ON MORPHOMETRIC, PHYSIOLOGICAL AND BLOOD PROFILE OF MIXED BRED RABBIT." Nigerian Journal of Agriculture and Agricultural Technology 4, no. 1 (2024): 216–26. http://dx.doi.org/10.59331/njaat.v4i1.645.

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This study was conducted to assess the morphometric, physiological and blood parameters of mixbred rabbits at different ages. One hundred and sixty rabbits comprising New Zealand White and Chinchilla Crossbreds were used. Body weight and body linear parameters were measured and recorded on weekly basis. Generalised Linear Model Procedure of SAS software was used to analyse the data set to examine the effects of sex and age on these parameters. The results indicated that sex significantly (P<0.05) affected morphometric and physiological parameters at 4, 8, 12, 32 and 48 weeks. Does (female r

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Sule, OJ, and ME Arhoghro. "Effect of Water Melon (Citrullus Lanatus) on Serum Glucose Level and Various Protein Parameters in Acetaminophen-Induced Wistar Albino Rats." Pharmaceutical and Chemical Journal 3, no. 2 (2016): 168–72. https://doi.org/10.5281/zenodo.13749332.

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The effect of aqueous extract of <em>Citrullus lanatus </em>(F) on acetaminophen-induced wistar albino rats was investigated. 25 male wistar rats were randomly shared into 5 groups of 5 rats per group and aqueous extract of <em>Citrullus lanatus</em> was administered orally to rats in groups 2 and 3 at 100 and 200mg/kg/per day respectively for twenty one days while, group4 received 100mg/kg body weight of vitamin C. Acetaminophen (1 mg/kg) was then administered to rat groups 2-5 daily for the same period of study. Blood samples were collected on the 22<sup>nd</sup> day of study and were used t

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Sree Veni, S. Manjula, and Sunita K. "Enzymatic changes in tissues of fish, Cirrhinus mrigala under lethal and sublethal exposure to cypermethrin (10% EC)." International Journal of Zoology and Applied Biosciences 7, no. 6S (2022): 52–62. http://dx.doi.org/10.55126/ijzab.2022.v07.i06.sp009.

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The effect of Cypermethrin (10% EC) formulations at sublethal and lethal concentrations on certain enzymes in tissue such as Aspartate Amino Transferase (AAT), Alanine Amino Transferase (ALAT), Acid Phosphatase (ACP)of the freshwater fish, Cirrhinus mrigala during and after the cessation of the exposure were observed. Ten fishes were exposed to the lethal and sublethal concentrations for a period of 4 days were sacrificed and tissues such as gill, kidney, liver, brain and muscle were analysed for biochemical parameters and remaining five fish were maintained in a clean well water for a period

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Suma, Sunjida Akter, and Qazi Shamima Akhter. "Effects of hyperthyroidism on serum alanine amino transferase and alkaline phosphatase levels in liver." Journal of Bangladesh Society of Physiologist 16, no. 1 (2021): 44–48. http://dx.doi.org/10.3329/jbsp.v16i1.54352.

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Background: Hyperthyroidism is one of the most common endocrine disorders. Thyroid hormones are essential for normal metabolic function of body cells including the liver cells. Again, metabolism of thyroid hormones takes place in liver. Therefore, hyperthyroidism may affect liver cells and causes change in hepatic enzymes level. Objective: To assess serum alanine aminotransferase (ALT) and alkaline phosphatase (ALP) levels in hyperthyroid patients. Methods: This cross sectional study was conducted in the Department of Physiology of Dhaka Medical College from July 2016 to June 2017. Total numbe

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Memon, Ghulam Rasool, Abdul Rahim Siyal, and Syeda Momina Muhammad. "Incidentally detected asymptomatic HBV positive subjects with slightly raised liver alanine amino transferase (alt)." JMMC 7, no. 1 (2019): 16–18. http://dx.doi.org/10.62118/jmmc.v7i1.11.

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Introduction: One third of world population (Two billion people) has been infected with hepatitis B virus. It is one of the most common infectious diseases among the world’s leading cause of death. HBV induced chronic liver disease is also an important precursor for the development of hepatocellular carcinoma even in absence of cirrhosis. Many subjects are un aware of viruses that are the cause of hepatitis except when they have been fully involved by the disease and it has become apparent with significant signs and symptoms. Objective: To discuss raised liver Alanine amino transferase (

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Kort, Sheila, Jeffrey Wickliffe, Arti Shankar, Hannah H. Covert, Maureen Lichtveld, and Wilco Zijlmans. "Association between Liver and Kidney Function and Birth Outcomes in Pregnant Surinamese Women Exposed to Mercury and Lead in the Caribbean Consortium for Research in Environmental and Occupational Health (CCREOH) Environmental Epidemiologic Cohort Study." Journal of Xenobiotics 14, no. 3 (2024): 1051–63. http://dx.doi.org/10.3390/jox14030059.

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Exposure to mercury (Hg) and lead (Pb), in combination with liver and kidney impairment, may result in adverse birth outcomes. From 408 women in the age range of 16 to 46 years, living in rural and urban areas in the interior of Suriname, we looked at the association between adverse birth outcomes and exposure to Hg and Pb in combination with liver and kidney function. This group of women represented a subcohort of pregnant women who participated in the Caribbean Consortium for Research in Environmental and Occupational Health (CCREOH)—Meki Tamara study. Liver function was assessed by measurin

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Mohseni, Mahmoud, Melika Ghelichpour, Mir Hamed Sayed Hassani, Zabih Ollah Pajand, and Reza Ghorbani Vaghei. "Effects of Dietary Thiamine Supplementation on Growth Performance, Digestive Enzymes’ Activity, and Biochemical Parameters of Beluga, Huso huso, Larvae." Journal of Applied Ichthyology 2023 (May 30, 2023): 1–10. http://dx.doi.org/10.1155/2023/6982536.

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Thiamine is a crucial nutrient in larval stage of fish, and thus, the present study aimed at evaluating the effects of dietary thiamine supplementation on survival, growth performance, and biochemical parameters of beluga, Huso huso, larvae. The fish larvae (50 ± 4.5 mg) were fed diets containing 0 (control), 5, 10, and 20 mg/kg thiamine for 26 days from 18 days after hatching to 44 days after hatching. Thiamine significantly increased the larvae survival, growth rate, digestive enzymes activity, and whole body protein and ash but decreased the whole body lipid and moisture P < 0.001 ). Als

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Jwaid, Kareem H., Majid S. Jabir, and Uday M. Nayef. "Toxicity of Porous Silicon Nanoparticles on Liver of Mice." Al-Mustansiriyah Journal of Science 28, no. 3 (2018): 209. http://dx.doi.org/10.23851/mjs.v28i3.552.

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Nanoparticles are a special group of materials with unique features and extensive application in diverse fields. The present work demonstrates the toxicity impact of porous silicon nanoparticles (PSNPs) on kidney parameter which is prepared by electrochemical etching method. the synthesis of porous silicon nanoparticles are conformed by using structural and optical properties from through scanning electron microscope and atomic force microscopy techniques. The effect of toxicity of these nanoparticles on the liver parameters in laboratory animals use four groups each groups involve three dupli

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Rana, Monika, Sunil Kumar, Meenakshi Rana, and Vinay Dhatwalia. "Role of Toona ciliate extract in diabetes against streptozotocin – nicotinamide induced diabetic rats." Journal of Ayurvedic and Herbal Medicine 2, no. 1 (2016): 6–10. http://dx.doi.org/10.31254/jahm.2016.2103.

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The present study was carried out to investigate the antihyperglycemic activity of the leaves of Toona ciliata hydroalcoholic extract in streptozotocin-induced diabetic rats. In the present study, effect of oral administration of T. ciliata leaves extract (0.2, 0.4g/kg body wt.) for 15 days on the level of blood glucose, serum cholesterol, triglycerides, urea, creatinine, aspartate amino transferase (AST) and alanine amino transferase (ALT) in normal and streptozotocininduced diabetic rats were evaluated. Histology of liver, kidney and pancreas were also studied. A significant decrease in bloo

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Tripathi, Indu, Shridhar N B, Jayakumar K, et al. "Hepatoprotective activity of methanol extract of Asteracantha longifolia in rats." Journal of Laboratory Animal Science 1, no. 2 (2019): 18–22. https://doi.org/10.48165/jlas.2019.1.2.4.

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The study was conducted to assess the hepatoprotective activity of Asteracantha longifolia in carbon tetra chloride (CCl4) induced hepatotoxicity in rats. The hepatoprotective effect of methanolic extract of whole plant of Asteracantha longifolia was studied by monitoring serum aspartate amino transferase (AST), serum alanine amino transferase (ALT) and histopathological alterations. Pre-treatment with methanol extract of Asteracantha longifolia in rats treated with CCl4 showed a significant inhibition (P<0.001) of rise in serum ALT and AST at all the doses tested (600, 900 or 1200 mg/kg).

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