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1

Zeb, Muhammad Asif, Syed Izaz Shah, Pervez Muhammad, Insafia Mehmood, Sajid Khan, and Sana Kanwal Khan. "Association of Biochemical Parameters in Chronic Drug Addict Patients; A Case-Control Study." Pakistan Journal of Medical and Health Sciences 16, no. 6 (2022): 845–46. http://dx.doi.org/10.53350/pjmhs22166845.

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Objective: To determine the effect of a biochemical parameter in chronic drug addict patients in Peshawar, Khyber Pukhtunkhwa. Materials and Methods: Blood samples of 90 drug addicts were randomly collected, 45 were hashish and 45 were heroin addicts. Drug addicts having hepatitis B and C infections were excluded from the study. Three milliliters of blood samples were collected in the lithium heparin tube using an aseptic technique for the determination of Alanine transaminase, Aspartate transaminase, Triglycerides, and Cholesterol. Results: Cholesterol was significantly decreased (P=0.00) in
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2

Jumah, Yashier Upling. "Effects of stocking density on blood chemistry and amino enzymatic activity of juvenile Nile tilapia Oreochromis niloticus (Linnaeus, 1758) in hyperosmotic rearing condition." GSC Biological and Pharmaceutical Sciences 11, no. 2 (2020): 036–43. https://doi.org/10.5281/zenodo.4271455.

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Nile tilapia Oreochromis niloticus, a euryhaline species, is a good candidate for culture in estuarine areas in the Philippine archipelago. Thus, the effects of stocking density on plasma cortisol, blood glucose, plasma aspartate transaminase (AST), and plasma alanine transaminase (ALT) were determined. The group of juvenile Nile tilapia O. niloticus (14.67 ± 0.12 cm TL and 44.57 ± 0.48 g W) was subjected to three different stocking densities (6, 12 & 24/60 L) for 14 days in 15‰ rearing condition. The experiment was composed of three treatments
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3

Compagnone, D., G. Federici, R. Massoud, L. Santoro, M. Anichini, and G. Palleschi. "Analysis for Transaminases in Serum with an Amperometric Glutamate Electrode." Clinical Chemistry 38, no. 11 (1992): 2306–10. http://dx.doi.org/10.1093/clinchem/38.11.2306.

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Abstract We determined transaminases in human blood serum with an amperometric glutamate biosensor. The probe was a hydrogen peroxide sensor assembled with appropriate selective membranes to enhance the probe specificity and lifetime. Calibration curves of glutamate were linear in the range 1-1000 mumol/L, with a response time of < 1 min. This probe was subsequently applied to the measurement of activities of aspartate and alanine aminotransferases in human sera. Analytical recovery studies demonstrated the suitability of the glutamate sensor by measuring 91-99% of added glutamate, 92-1
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4

Goldie, D. J., and A. A. McConnell. "Serum alanine transaminase (ALT) reference ranges estimated from blood donors." Journal of Clinical Pathology 43, no. 11 (1990): 929–31. http://dx.doi.org/10.1136/jcp.43.11.929.

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5

Medeni, Volkan, Sultan Pınar Çetintepe, Rabia Aygür, Fatma Bozdağ, and İrem Medeni. "Effects of occupational exposure on the hematologic parameters among welders." Acta Medica 55, no. 1 (2024): 74–80. http://dx.doi.org/10.32552/2024.actamedica.979.

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Introduction: The effect of prolonged exposure to welding fumes on blood levels remains an unresolved question. In our study, we aimed to determine the effects of metal fume exposure on various blood parameters in welders. Materials and Methods: The study was cross-sectional. It included all male welding workers admitted to a health institution, a reference hospital for occupational diseases, for 2021. It was conducted with 254 individuals. The variables examined included age, duration of employment, smoking habit, body mass index, hemoglobin levels, erythrocyte, leukocyte and platelet counts,
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6

Matsumi, Junya, and Tetsufumi Sato. "Protective effect of propofol compared with sevoflurane on liver function after hepatectomy with Pringle maneuver: A randomized clinical trial." PLOS ONE 18, no. 8 (2023): e0290327. http://dx.doi.org/10.1371/journal.pone.0290327.

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While the Pringle maneuver reduces intraoperative blood loss in hepatectomies, this technique can also be hepatotoxic. Hepatectomies require general anesthesia with propofol or volatile anesthetics like sevoflurane, agents known to offer multi-organ protection. However, their clinical effect after liver resection is unclear. We aimed to assess the effect of the two anesthetics on post-hepatectomy liver damage via measuring liver function tests. Fifty-six patients who underwent elective hepatectomies with the Pringle maneuver due to metastatic hepatic masses were preoperatively randomized to be
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7

Ali, Rasul, Dler Ali, Zhyan Ahmed, Amal Ahmed, Dilvin Hassen, and Rozy Tahir. "Comparison of deferasirox and deferoxamine effect on liver enzyme activities and ferritin level in patients with beta-thalassemia." Zanco Journal of Medical Sciences 24, no. 3 (2020): 354–59. http://dx.doi.org/10.15218/zjms.2020.042.

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Background and objective: Patients on blood transfusion may develop complications related to iron overload and the effects of chelating agents (drugs), which adversely affect the liver in thalassemia, which is a genetic blood disorder of hemoglobin synthesis that causes severe anemia. This study aimed to assess the effect of deferasirox and deferoxamine drugs on liver enzyme activities (aspartate transaminase, alanine transaminase, and alkaline phosphatase), and serum ferritin level in β_thalassemic patients. Methods: This study was carried out in Erbil city from October 2017 to February 2018.
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8

Davidson, D. Fraser. "Effects of contamination of blood specimens with liquid potassium-EDTA anticoagulant." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 39, no. 3 (2002): 273–80. http://dx.doi.org/10.1258/0004563021901973.

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Background Use of the anticoagulant EDTA, in high-concentration liquid form, in blood collection tubes can lead to cross-contamination of routine biochemistry specimens. Methods In the present study, tests affected by EDTA in the sample were potassium, calcium, magnesium, unsaturated iron-binding capacity, bicarbonate, aspartate transaminase, alanine transaminase, lactate dehydrogenase, creatine kinase, alkaline phosphatase and amylase. The likely mechanisms are discussed. Conclusions In the interests of best practice, the identification of subtle contamination of blood specimens for biochemic
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9

Wajid, Usman, Ahmed Haider, Toaqeer Salman, Muhammad Luqman, and Paris Anwar. "Assessment and Relationship of Elevated Serum Alanine Transaminase Level in Reference with Obesity." Journal of Pharmaceutical Research International 35, no. 15 (2023): 24–35. http://dx.doi.org/10.9734/jpri/2023/v35i157377.

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Imbalances between energy gained and exhausted results in abnormal fat accumulation in the tissues of human body and ultimately leads to obesity. Obese people vary not only in the quantity of extra fat that they store, but also in the local distribution of fat within the body. Proportions of obesity are increasing alarmingly in many portions of the world. Pakistan is ranked 9th among 188 countries in carrying obese population, in terms of absolute numbers. Alanine Transaminase is commonly used to identify patients with liver disease. This study was designed to access the level of alanine trans
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10

Ikpeazu, V. O., S. A. U. Offiah, J. Chikezie, et al. "Effect of Malaria Parasite on Hepatic Parameters in People Living in Aba Metropolis." American Journal of Health, Medicine and Nursing Practice 7, no. 13 (2023): 25–29. http://dx.doi.org/10.47672/ajhmn.1318.

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Purpose: In Nigeria, malaria continues to be a huge public health problem. Incidentally, malaria is caused by either Plasmodium falciparum or Plasmodium vivax. Malaria associated deaths in Metropolis area is mainly due to Plasmodium falciparum. Plasmodium parasite is primarily transmitted by the bite of an infected female anopheles mosquito during blood meal though this can also occur through exposure to infected blood products (blood transfusion) and by congenital transmission. This study therefore aimed at investigating the effect of malaria parasite on hepatocytes by monitoring enzyme activ
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11

Yagishita, Hironobu, Hideaki Kagaya, Mitsuru Saito, et al. "Effects of NR1I2 and ABCB1 Genetic Polymorphisms on Everolimus Pharmacokinetics in Japanese Renal Transplant Patients." International Journal of Molecular Sciences 23, no. 19 (2022): 11742. http://dx.doi.org/10.3390/ijms231911742.

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The purpose of this study was to evaluate the effects of NR1I2 (7635G>A and 8055C>T) and ABCB1 (1236C>T, 2677G>T/A, and 3435C>T) genetic polymorphisms on everolimus pharmacokinetics in 98 Japanese renal transplant patients. On day 15 after everolimus administration, blood samples were collected just prior to and 1, 2, 3, 4, 6, 9, and 12 h after administration. The dose-adjusted area under the blood concentration–time curve (AUC0-12) of everolimus was significantly lower in patients with the NR1I2 8055C/C genotype than in those with other genotypes (p = 0.022) and was significant
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12

Pavel, Omer, Bahjat Abbas, and Hiewa Dyary. "Some Physiological and Serum Biochemical Reference Values of Adult Chukar Partridge (Alectoris chukar Kurdestanica) in Kurdistan Region-Iraq." Al-Anbar Journal of Veterinary Sciences 15, no. 2 (2022): 87–96. http://dx.doi.org/10.37940/ajvs.2022.15.2.9.

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The physiological parameters and blood biochemical parameters of wild Chukar partridges in the Sulaymaniyah Governorate of the Kurdistan Region-Iraq were measured in this study. During this research, 27 healthy Alectoris chukar partridges (9 males, 18 females), 8–12 months, were captured in the mountains of Penjwin district in the east of Sulaimani City from March to July 2022. Physiological parameters, including weight, heart rate (HR), respiratory rate (RR), and cloacal temperature (CT), were recorded for each partridge. Blood samples were collected from the jugular or wing vein to determine
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13

Dar, Salman Farooq, Abeera Kali, Malik Muhammad Atif, Saad Javed, Muhammad Burhan Majeed Rana, and Umair Haider. "Reference values of alanine transaminase and aspartate transaminase in apparently healthy individuals and their relation with body mass index." Professional Medical Journal 27, no. 12 (2020): 2613–17. http://dx.doi.org/10.29309/tpmj/2020.27.12.4649.

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Objectives: The purpose of this study is to determine the reference values of ALT and AST in healthy, young individuals of Lahore and compare them with international reference values and to determine its relation with Body Mass Index. Study Design: Descriptive Cross Sectional Study. Setting: Department of Pathology, Jinnah Hospital Lahore. Period: March 2017 to May 2017. Material & Methods: Blood Samples were drawn from apparently healthy volunteers and medical students coming to Blood Bank of Jinnah Hospital, Lahore for blood donation, and their ALT and AST values were obtained after scre
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14

Tomovska, Julijana, Gordana Dimitrovska, Stefce Presilski, and Kristina Velkova. "Whey and its inhibition of liver enzymes." Biotehnologija u stocarstvu 32, no. 1 (2016): 59–70. http://dx.doi.org/10.2298/bah1601059t.

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Whey is lately used as functional food, and whey proteins and albumens are considered to have therapeutic influence on diseases associated with oxidative stress. Whey proteins contribute to the reduction of the level of transaminases in blood, especially of alanine transaminase. In this paper we examine some components (total proteins, albumens from whey proteins, minerals: potassium (K), iron (Fe), calcium (Ca) and phosphorus (P), from whey and their inhibition effects to transaminases (alanine aminotransferase (ALT), aspartate aminotransferase (AST), and ? glutamyl transferase (? -GT)). The
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15

Day, Rachel L., Darryl J. Heard, and Dana LaBlanc. "THE EFFECT OF TIME AT WHICH PLASMA SEPARATION OCCURS ON BIOCHEMICAL VALUES IN SMALL ISLAND FLYING FOXES (PTEROPUS HYPOMELANUS)." Journal of Zoo and Wildlife Medicine 32, no. 2 (2001): 206–8. https://doi.org/10.5281/zenodo.13478010.

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(Uploaded by Plazi for the Bat Literature Project) Heparinized blood samples from 15 adult small island flying foxes (Pteropus hypomelanus) were stored at 22ЊC for 0-, 6-, and 24-hr intervals prior to centrifugation and separation of plasma from erythrocytes. Mean plasma biochemical values of 16 analytes were determined from all samples. Mean values of blood urea nitrogen, creatinine, total protein, albumin, globulin, alkaline phosphatase, alanine transaminase, aspartate transaminase, cholesterol, calcium, sodium, and bilirubin did not change significantly over 24 hr at 22ЊC. Glucose was decre
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16

Day, Rachel L., Darryl J. Heard, and Dana LaBlanc. "THE EFFECT OF TIME AT WHICH PLASMA SEPARATION OCCURS ON BIOCHEMICAL VALUES IN SMALL ISLAND FLYING FOXES (PTEROPUS HYPOMELANUS)." Journal of Zoo and Wildlife Medicine 32, no. 2 (2001): 206–8. https://doi.org/10.5281/zenodo.13478010.

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(Uploaded by Plazi for the Bat Literature Project) Heparinized blood samples from 15 adult small island flying foxes (Pteropus hypomelanus) were stored at 22ЊC for 0-, 6-, and 24-hr intervals prior to centrifugation and separation of plasma from erythrocytes. Mean plasma biochemical values of 16 analytes were determined from all samples. Mean values of blood urea nitrogen, creatinine, total protein, albumin, globulin, alkaline phosphatase, alanine transaminase, aspartate transaminase, cholesterol, calcium, sodium, and bilirubin did not change significantly over 24 hr at 22ЊC. Glucose was decre
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17

Day, Rachel L., Darryl J. Heard, and Dana LaBlanc. "THE EFFECT OF TIME AT WHICH PLASMA SEPARATION OCCURS ON BIOCHEMICAL VALUES IN SMALL ISLAND FLYING FOXES (PTEROPUS HYPOMELANUS)." Journal of Zoo and Wildlife Medicine 32, no. 2 (2001): 206–8. https://doi.org/10.5281/zenodo.13478010.

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(Uploaded by Plazi for the Bat Literature Project) Heparinized blood samples from 15 adult small island flying foxes (Pteropus hypomelanus) were stored at 22ЊC for 0-, 6-, and 24-hr intervals prior to centrifugation and separation of plasma from erythrocytes. Mean plasma biochemical values of 16 analytes were determined from all samples. Mean values of blood urea nitrogen, creatinine, total protein, albumin, globulin, alkaline phosphatase, alanine transaminase, aspartate transaminase, cholesterol, calcium, sodium, and bilirubin did not change significantly over 24 hr at 22ЊC. Glucose was decre
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18

Day, Rachel L., Darryl J. Heard, and Dana LaBlanc. "THE EFFECT OF TIME AT WHICH PLASMA SEPARATION OCCURS ON BIOCHEMICAL VALUES IN SMALL ISLAND FLYING FOXES (PTEROPUS HYPOMELANUS)." Journal of Zoo and Wildlife Medicine 32, no. 2 (2001): 206–8. https://doi.org/10.5281/zenodo.13478010.

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(Uploaded by Plazi for the Bat Literature Project) Heparinized blood samples from 15 adult small island flying foxes (Pteropus hypomelanus) were stored at 22ЊC for 0-, 6-, and 24-hr intervals prior to centrifugation and separation of plasma from erythrocytes. Mean plasma biochemical values of 16 analytes were determined from all samples. Mean values of blood urea nitrogen, creatinine, total protein, albumin, globulin, alkaline phosphatase, alanine transaminase, aspartate transaminase, cholesterol, calcium, sodium, and bilirubin did not change significantly over 24 hr at 22ЊC. Glucose was decre
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19

Afroz, Farhana, Nasima Sultana, Ashiqur Rahman, et al. "A Comparative Study of Hepatic Enzymes Between Preeclampsia and Normal Pregnant Women." Journal of Dhaka Medical College 29, no. 1 (2021): 18–22. http://dx.doi.org/10.3329/jdmc.v29i1.51165.

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Background: Preeclampsia is a multisystem disorder, unique to pregnancy that is usually associated with high blood pressure and proteinuria after 20 week of gestation. Abnormal liver function tests occur in 20% to 30% of pregnancies complicated by preeclampsia and are associated with a higher risk of adverse maternal and fetal outcome.
 Objective: To observe the alteration of hepatic enzymes in preeclampsia.
 Methods: The present cross-sectional study was carried out in the Department of Biochemistry, Dhaka Medical College, and Dhaka from July 2015 to June 2016. A total number of one
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20

Sajid, M., M. Kashif, A. Rasool, Muhammad Umer Farooq, and W. Nazar. "Detection of Selected Heavy Metals and Their Effect on Haematological and Serum Biochemical Values in Naturally Exposed Cattle." Journal of Agricultural Sciences – Sri Lanka 20, no. 2 (2025): 182–87. https://doi.org/10.4038/jas.v20i2.9951.

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Purpose: The present study was conducted in two areas (one clean and one contaminated) of the district of Jhang, Pakistan, to determine the concentration of the possible heavy metals, lead and cadmium, in the blood. For this purpose, two hundred samples were collected, one hundred from each area.Research Method: These samples were analyzed for lead and cadmium using the atomic absorption spectrophotometric method. The haematological parameters packed cell volume, total erythrocyte count, Haemoglobin, total leucocyte count, differential leukocyte count, and erythrocyte sedimentation rate were m
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21

Kolodkina, Elena, and Sergey Lytaev. "The Dynamics of Transaminase and Alkaline Phosphatase Activities in the “Mother–Placenta–Fetus” Functional System." Biomedicines 13, no. 3 (2025): 626. https://doi.org/10.3390/biomedicines13030626.

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Background: The timing of delivery depends on the condition of the fetus and the mother’s body, which is reflected in both the incretion of enzymes in the pregnant woman’s body and their use by the developing fetus in the anabolic process. The aim: This work was aimed to analyze the activities of transaminases (aspartate aminotransferase (AST) and alanine aminotransferase (ALT)) and alkaline phosphatase (AlPh) in liquid media (blood serum, amniotic fluid, umbilical cord blood, and placental homogenate) in pregnant women in each trimester of pregnancy and in the postpartum period, considering t
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22

IANCU, Mihaela Adela, Dumitru MATEI, and Gabriel Cristian BEJAN. "Childhood obesity – a serious problem in our society." Romanian Journal of Medical Practice 10, no. 2 (2015): 176–81. http://dx.doi.org/10.37897/rjmp.2015.2.15.

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The childhood obesity is a serious public health problems. The prevalence of childhood obesity is on the rise. The most recent recommendations regarding prevention of childhood obesity focus on increased exercise and improved diet to prevent childhood obesity and on incresed prevention of perinatal factors that determine the development of childhood obesity. Material and method. During 2013-2015 we evaluated a number of 78 patients. We took a standardized history, performed a physical examination, measured height, weight, blood pressure, heart rate, calculated body mass index. Also we analyzed
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23

Osuagwu, U. O., C. O. Ujowundu, L. A. Nwaogu, and R. N. Nwaoguikpe. "Sublethal Effects of Ternary Mixtures of Polycyclic Aromatic Hydrocarbons on Selected Liver Biomarkers of Clarias gariepinus." Journal of Applied Sciences and Environmental Management 27, no. 3 (2023): 525–30. http://dx.doi.org/10.4314/jasem.v27i3.16.

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The effect of ternary mixtures of polycyclic aromatic hydrocarbons in Clarias gariepinus was investigated. Apparently healthy juvenile fish (n = 90) weighing 19.7±1.8 g were exposed to sublethal concentrations of naphthalene, phenathrene and benzo[a]pyrene over a period of 35 days after which liver biomarker analyses were carried out on blood plasma fraction. The observed total plasma protein was 35.1 g/L while the albumin and total bilirubin concentrations were 15.9 g/L and 4.6 μmol/L respectively. The plasma concentrations of the liver enzymes were 25.27 IU/L, 9.37 IU/L, and 28.01 IU/L for a
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24

Botha, C. J., T. W. Naudé, G. E. Swan, Marcella M. Ashton, and J. F. Van der Wateren. "Suspected cycad (Cycas revoluta) intoxication in dogs." Journal of the South African Veterinary Association 62, no. 4 (1991): 189–90. http://dx.doi.org/10.4102/jsava.v62i4.1790.

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Three dogs which ingested part of the stem of a Japanese cycad (Cycas revoluta) vomited repeatedly within hours after ingestion, showed marked depression, severely congested mucous membranes, increased thirst and profuse salivation. Subsequent haematological and blood chemical investigation revealed elevated serum concentrations of alanine transaminase, an initial mild lymphocytopenia, thrombocytopenia and a leucocytosis. The dogs recovered uneventfully.
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25

Novikov, D. G., A. V. Indutnyy, N. A. Trofimovich, N. I. Sidenko, G. A. Borzenok, and L. V. Gorbunova. "Clinical and biochemical aspects of coagulation control in patients with atrial fibrillation and excessive alcohol consumption." Kazan medical journal 96, no. 5 (2015): 734–41. http://dx.doi.org/10.17750/kmj2015-734.

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Aim. Reveal the influence of excessive alcohol consumption on blood coagulation system, levels of blood proteins in patients with atrial fibrillation treated with warfarin. Methods. The study included 80 patients with a diagnosis of atrial fibrillation, treated with vitamin K antagonists. The study group included 34 patients with excessive alcohol consumption (according to the questionnaire), the comparison group - 46 patients with no excessive alcohol consumption. Transferrin, hemopexin, aspartate transaminase, alanine transaminase, gamma-glutamyl transferase, carbohydrate-deficient transferr
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Al-Awad, Haitham Mohammed, and Sanaa Mohammed Ali Al-Jalal. "Effect of Toxoplasmosis on some biochemical parameters in aborted Women in Al-Najaf Al-Ashraf Governorate." Kufa Journal For Veterinary Medical Sciences 2, no. 2 (2011): 26–36. http://dx.doi.org/10.36326/kjvs/2011/v2i23898.

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The present study was conducted to evaluate the effects of infection of women with toxoplasmosis on some serum biochemical parameters. 180 samples of blood were collected from aborted women . The percentage of toxoplasma infection depending Enzyme- Linked Immunosorbent Assay (ELISA) to the antibodies IgG and IgM were 42.77%. The results of biochemical analysis showed that infection with toxoplasma caused significant elevation of Nitric Oxide, Malondialdehyde, copper, alanine transaminase and aspartate transaminase enzymes. Aswell as the concentrations of Gluthanione, calcium and zinc were redu
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Al-Awad, Haitham Mohammed, and Sanaa Mohammed Ali Al-Jalal. "Effect of Toxoplasmosis on some biochemical parameters in aborted Women in Al-Najaf Al-Ashraf Governorate." Kufa Journal For Veterinary Medical Sciences 2, no. 2 (2011): 26–36. http://dx.doi.org/10.36326/kjvs/2011/v2i23898.

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The present study was conducted to evaluate the effects of infection of women with toxoplasmosis on some serum biochemical parameters. 180 samples of blood were collected from aborted women . The percentage of toxoplasma infection depending Enzyme- Linked Immunosorbent Assay (ELISA) to the antibodies IgG and IgM were 42.77%. The results of biochemical analysis showed that infection with toxoplasma caused significant elevation of Nitric Oxide, Malondialdehyde, copper, alanine transaminase and aspartate transaminase enzymes. Aswell as the concentrations of Gluthanione, calcium and zinc were redu
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Veeramalla, Vydehi. "Pseudocholinesterase, aspartate transaminase, alanine transaminase as markers for cervical cancer: a study in a tertiary care hospital." International Journal of Advances in Medicine 4, no. 6 (2017): 1557. http://dx.doi.org/10.18203/2349-3933.ijam20175134.

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Background: Cervical cancer is a malignant neoplasm arising from cells originating in the cervix, almost always caused by human papillomavirus (HPV). Butyrylcholinesterase is a non-specific cholinesterase enzyme that hydrolyses different choline esters. PCHE levels were lower than the normal at all the stages of cancer cervix. The present study was attempted to find out the role of some of the biochemical markers like serum pseudocholinesterase (PCHE), serum aspartate transaminase (AST), and serum alanine transaminase (ALT), in malignancy of the uterine cervix.Methods: 60 patients aged between
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29

MURKUTE, PRANJALI M., PRAJAKTA S. KURALKAR, S. W. HAJARE, et al. "Metabolic profile of Purnathadi buffaloes during transition period." Indian Journal of Animal Sciences 94, no. 11 (2024): 938–41. http://dx.doi.org/10.56093/ijans.v94i11.154392.

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This study investigated the impact of the transition period on the blood metabolic profile of Purnathadi buffaloes in Vidarbha’s tropical climate. Blood samples were taken from nine pregnant buffaloes 21 days before parturition, at parturition, and 21 days after parturition. Triglycerides, albumin, globulin, alanine transaminase, aspartate transaminase, calcium, haemoglobin, packed cell volume, mean corpuscular haemoglobin, total leukocyte count, eosinophils, basophils and monocytes were non- significantly affected. However, non-esterified fatty acids, total cholesterol, glucose, total protein
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Topolyanskaya, Svetlana V., Rachina S.A., Karine A. Lytkina, Georgiy G. Melkonyan, and Yulia A. Savochkina. "Interleukin-6 Inhibitor Olokizumab in Hospitalized Adults with Moderate COVID-19: Results of a Single Center Observational Study." West Kazakhstan Medical Journal 66, no. 4 (2024): 453–59. https://doi.org/10.18502/wkmj.v66i4.17780.

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A single-center observational study was performed to evaluate the effectiveness and safety of the interleukin-6 inhibitor olokizumab in hospitalized adults with moderate COVID-19. This study enrolled 337 patients aged from 22 to 96 years old. After the administration of olokizumab, there was a significant reduction in body temperature, decrease in CRP, and an increase in the levels of blood cells. Revealed clinical improvement was seen in 69.7% of cases, 8.5% of patients showed deterioration in their condition and were transferred to the ICU, 13.6% died. Olokizumab was well tolerated except fo
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Chidi, Ugwuowo Leonard, Cordelia Ifeyinwa Ebenebe, and Odia Peace Ngozi. "Growth performance, Haematological and Serum biochemistry of broilers fed diets containing Vitex doniana leaf meal." Revista de Ciências Agroveterinárias 23, no. 1 (2024): 89–98. http://dx.doi.org/10.5965/223811712312024089.

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This experiment was conducted to investigate the growth performance, haematological and serum biochemistry indices of broilers fed diets containing Vitex doniana leaf meal (VDLM). A total of 120 unsexed broilers were allocated to four treatments of T1, T2, T3 and T4 and replicated three times with ten birds per replicate in a Completely Randomized Design. The birds in each treatment were fed with diets containing 0.0, 2.5, 5.0 and 7.5% VDLM respectively. Growth performances, packed cell volume, red blood cell count, haemoglobin, white blood cell count, lymphocytes, neutrophils, mean corpuscula
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El-Sayed, Gehad, Mohamed El-Diasty, and Shaimaa Zayed. "Pharmacological studies of Pediococcus on performance and some hematological and biochemical parameters in cattle." Mansoura Veterinary Medical Journal 20, no. 2 (2019): 60–69. http://dx.doi.org/10.35943/mvmj.2019.22.106.

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The use of Pediococcus (23×106 CFU/calf/day) orally in drinking milk once daily for one month in Holstein calves have highly significant effect on blood picture ,liver function tests, kidney function test ,blood electrolytes and body weight in cow calves. There were a significant increase in total erythrocytes count , hemoglobin content, packed cell volume, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, thrombocyte count, total leucocytes count, neutrophils counts, eosinophil, basophils, total protein and its fractions, level of alkaline phosph
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Ekun, Oloruntoba Ayodele, Oluwatumininu Mary Olawumi, Christian Chigozie Makwe, and Nkeiruka Ogochukwu Ogidi. "Biochemical Assessment of Renal and Liver Function among Preeclamptics in Lagos Metropolis." International Journal of Reproductive Medicine 2018 (July 31, 2018): 1–6. http://dx.doi.org/10.1155/2018/1594182.

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Objectives. Preeclampsia is a pregnancy specific syndrome. Studies have shown that preeclampsia has multiorgan dysfunction effects. This study evaluated biomarkers of renal and liver function among preeclamptic Nigerian women. Study Design. This was a cross-sectional study conducted among 49 preeclamptic women and 50 normotensive healthy pregnant women. Method. The baseline data comprising age, gestational age, and blood pressure were obtained. Venous blood and spot urine samples were collected from each participant. Plasma obtained from blood samples taken into lithium heparinized vacutainer
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34

Riyadh Hussein Wally. "Effects of Chronic Kidney Disease on Some Liver Enzymes Activity Before and After Dialysis." journal of the college of basic education 22, no. 96 (2022): 89–94. http://dx.doi.org/10.35950/cbej.v22i96.9018.

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The aim of the study is to compare the activity level of some liver enzymes such as aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) of chronic kidney disease (CKD) patient before and after dialysis. 50 blood samples of male and female with chronic kidney disease compared with (55) healthy persons samples as control group ,both group aged between 20-65 years and have no history of liver diseases. The results of study showed a decrease (P<0.001) in activity level of (AST) and (ALT) ,while the study showed elevated (P<0.001) in activity level of (ALP)
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35

Osuagwu, U. O., C. O. Ujowundu, L. A. Nwaogu, and R. N. Nwaoguikpe. "Biochemical and Oxidative Stress Responses in Clarias gariepinus Exposed to Sublethal Concentrations of Benzo[a]pyrene." Asian Journal of Biochemistry, Genetics and Molecular Biology 13, no. 3 (2023): 15–22. http://dx.doi.org/10.9734/ajbgmb/2023/v13i3294.

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The effect of benzo[a]pyrene (BaP) on selected plasma biochemical parameters of the tropical African catfish C. gariepinus was investigated. Apparently healthy juvenile fish (n = 90; mass = 19.7 ± 1.8 g) were exposed to sublethal concentrations of BaP over a period of 35 days after which haematological and plasma biochemical analysis were carried out on whole blood and plasma respectively. While there were significant declines in red blood cell count (RBC), hemoglobin, haematocrit and platelet count, significant elevations were observed in mean cell volume (MCV), mean cell haemoglobin concentr
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36

Kumbasar, Seda. "Relationship between earthquake ınjuries and ınflammatory blood parameters." Dicle Tıp Dergisi 52, no. 2 (2025): 235–44. https://doi.org/10.5798/dicletip.1722859.

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Objective: An earthquake is a significant natural disaster with the potential to cause considerable mortality, economic disruption, and psychological effects. The purpose of this study was to investigate the impact of laboratory parameters on the triage, treatment, and survival of patients with injuries of varying severity who sustained traumatic injuries amid debris. Methods: This retrospective study included 1250 adult earthquake victims who were received outpatients and inpatient treatment in our hospital between February 6 and February 23, 2023. The patients were classified into three cate
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Zhu, Wei, Minli Chen, Qiyang Shou, Yinghua Li, and Fuliang Hu. "Biological Activities of Chinese Propolis and Brazilian Propolis on Streptozotocin-Induced Type 1 Diabetes Mellitus in Rats." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–8. http://dx.doi.org/10.1093/ecam/neq025.

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Propolis is a bee-collected natural product and has been proven to have various bioactivities. This study tested the effects of Chinese propolis and Brazilian propolis on streptozotocin-induced type 1 diabetes mellitus in Sprague-Dawley rats. The results showed that Chinese propolis and Brazilian propolis significantly inhibited body weight loss and blood glucose increase in diabetic rats. In addition, Chinese propolis-treated rats showed an 8.4% reduction of glycated hemoglobin levels compared with untreated diabetic rats. Measurement of blood lipid metabolism showed dyslipidemia in diabetic
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38

Selvakumar, Kandaswamy, Senthamilselvan Bavithra, Sekaran Suganya, Firdous Ahmad Bhat, Gunasekaran Krishnamoorthy, and Jagadeesan Arunakaran. "Effect of Quercetin on Haematobiochemical and Histological Changes in the Liver of Polychlorined Biphenyls-Induced Adult Male Wistar Rats." Journal of Biomarkers 2013 (October 1, 2013): 1–12. http://dx.doi.org/10.1155/2013/960125.

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Polychlorinated biphenyls exposure damages the rat liver cells. Hematological parameters such as hemoglobin, packed cell volume, red-blood cells, white-blood cells, neutrophils, platelet counts, and RBC indices were significantly decreased. Polymorphs, eosinophil counts, and erythrocyte sedimentation rate were significantly increased. Serum liver enzymes such as aspartate transaminase, alanine transaminase, alkaline phosphatase, and gamma-glutamyl transferase were increased by PCBs treatment. Serum lipid profiles such as cholesterol, triglycerides, low-density lipoproteins and very-low-density
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39

Gottender, Nicole L., and Elliott R. Jacobson. "Effect of venipuncture sites on hematologic and clinical biochemical values in desert tortoises (Gopherus agassizii)." American Journal of Veterinary Research 56, no. 1 (1995): 19–21. http://dx.doi.org/10.2460/ajvr.1995.56.01.19.

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SUMMARY Paired blood samples were collected from the postoccipital venous plexus and jugular vein of desert tortoises (Gopherus agassizii) for hematologic and plasma biochemical analyses. Comparison of hematologic values revealed significantly (P ≤ 0.05) lower pcv, rbc count, wbc count, and hemoglobin values for samples obtained from the occipital site. When comparisons were made between plasma biochemical values for the 2 sites, significant (P ≤ 0.05) differences were measured for: glucose, potassium, chloride, uric acid, calcium, phosphorous, total protein, albumin, globulin, alkaline phosph
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Pargaputri, Agni Febrina, and Dwi Andriani. "Hepatocellular Liver Function of Immunosuppressed Rats with Oral Candidiasis after Hyperbaric Oxygen Treatment: Alanine Transaminase and Aspartate Transaminase Levels." Archives of Orofacial Sciences 16, Supp. 1 (2021): 5–9. http://dx.doi.org/10.21315/aos2021.16.s1.2.

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Hepatocellular utility is observed by measuring the hepatocellular enzymes. Changes in its serum levels are related to liver dysfunction. Liver is one of the immunoprotective organs. Continuous use of immunosuppressive drugs can cause oral candidiasis and give effects to liver function. Hyperbaric oxygen treatment (HBOT), while reducing fungal infections, can also repair the liver function. The aim of this study was to investigate the alanine transaminase (ALT) and aspartate transaminase (AST) levels of immunosuppressed rats with oral candidiasis treated with hyperbaric oxygen. Twelve Wistar r
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Ekundayo, Esther Aanuoluwa. "Assessment of the haematological parameters and biochemical indices of albino rats fed with spores of Trichoderma viride." Brazilian Journal of Biological Sciences 7, no. 17 (2020): 319–26. http://dx.doi.org/10.21472/bjbs(2020)071707.

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The haematological as well as some enzymes biomarkers of albino rats orogastically dosed with different concentrations of Trichoderma viride as well as T. viride subjected to various treatments were evaluated. Generally, red blood cell count, haemoglobin content and packed cell volume of the control group were significantly higher than that of animals dosed with different concentrations of T. viride. The same trend was observed when T. viride was amended with 1% lactose, sodium nitrate and sodium chloride. There were no significant differences in the alanine aspartate, alkaline phosphatase and
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42

Qazi, Adil Iqbal, Bashir Ahmad, Muhammad Umar Khayam Sahibzada, et al. "Evaluation of Antidiabetic Activity of Oxadiazole Derivative in Rats." Evidence-Based Complementary and Alternative Medicine 2023 (April 25, 2023): 1–15. http://dx.doi.org/10.1155/2023/1141554.

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The oxadiazole ring has long been used for the treatment of several diseases. This study aimed to analyze the antihyperglycemic and antioxidant roles of the 1,3,4-oxadiazole derivative with its toxicity. Diabetes was induced through intraperitoneal administration of alloxan monohydrate at 150 mg/kg in rats. Glimepiride and acarbose were used as standards. Rats were divided into groups of normal control, disease control, standard, and diabetic rats (treated with 5, 10, and 15 mg/kg of 1,3,4-oxadiazole derivative). After 14 days of oral administration of 1,3,4-oxadiazole derivatives (5, 10, and
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43

Damaziak, Krzysztof, Monika Michalczuk, Żaneta Zdanowska-Sąsiadek, et al. "Effects of genotype on hematological and serum biochemical responses of turkey hens to stress." Archives Animal Breeding 60, no. 1 (2017): 9–17. http://dx.doi.org/10.5194/aab-60-9-2017.

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Abstract. Stress accompanying animal production is both an indicator of welfare and a factor that affects economic parameters. Dynamic development of alternative poultry production systems such as outdoor, free range or ecological, strives to achieve best-quality products and to improve the living conditions of birds. Apart from the type and intensity of the external stimuli, the response to stress is determined genetically. Poultry rearing in the aforementioned systems requires selecting the appropriate genotype of birds, often including crosses of fast-growing and slow-growing lines. The obj
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44

Liu, Pang-Yen, Yu-Kai Lin, Kai-Wen Chen, et al. "Association of Liver Transaminase Levels and Long-Term Blood Pressure Variability in Military Young Males: The CHIEF Study." International Journal of Environmental Research and Public Health 17, no. 17 (2020): 6094. http://dx.doi.org/10.3390/ijerph17176094.

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Background: An inverse relationship of serum liver transaminases and mortality might be due to better blood pressure control in hypertensive patients. Whether it holds true regarding such an association for long-term blood pressure variability (BPV) in those without antihypertensive therapy is unclear. Methods: A population of 1112 military males without antihypertensive medications, aged 32 years, was collected from a retrospective longitudinal study in Taiwan. Serum liver aspartate and alanine transaminase (AST and ALT) levels were obtained from a 12 h-fast blood sample of each participant.
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45

Shakib, Marie-Christine, Shreef Gabrial, and Gamal Gabrial. "Rice Bran Oil Compared to Atorvastatin for Treatment of Dyslipidemia in Patients with Type 2 Diabetes." Open Access Macedonian Journal of Medical Sciences 2, no. 1 (2014): 95–102. http://dx.doi.org/10.3889/oamjms.2014.017.

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Objective: To compare the effect of rice bran oil versus statins (atorvastatin drug) on blood glucose, glycosylated hemoglobin (HbA1C) and serum lipid profiles in patients with type 2 diabetes. The safety of the tested rice bran oil and atorvastatin were investigated. Fatty acids contents of RBO, olive and sesame oil were also assessed.Materials and Methods: Forty four eligible patients with type 2 diabetes and moderately hyperlipidemic were randomly and equally allocated into two groups, rice bran oil (RBO) group and atorvastatin group. The RBO group received a low-calorie diet and consumed 3
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46

Journal, Baghdad Science. "The effect of Tramadol on some blood and biochemical parameters of male rats (Rattus norvegicus)." Baghdad Science Journal 12, no. 3 (2015): 496–502. http://dx.doi.org/10.21123/bsj.12.3.496-502.

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The present study aimed to explain the dose-dependent possible deleterious effects of 30 day administration of Tramadol on some hematological and biochemical parameters of laboratory male rats (Rattus norvegicus), the study consisted of eighteen adult male rats randomly divided into three equal groups (each of six). Group 1 (control) were treated by intraperitoneal injection of normal saline solution (0.2 ml), group two (low dose) was treated by intraperitonealy (i.p) injection of Tramadol at a dose of 50 mg/kg/day, group three (high dose) was treated by intraperitonealy injection of Tramadol
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Aldiwan, Mohammed A., Del M. Hassan Alzobidy, and Mohammed A. Younis. "The effect of Tramadol on some blood and biochemical parameters of male rats (Rattus norvegicus)." Baghdad Science Journal 12, no. 3 (2015): 496–502. http://dx.doi.org/10.21123/bsj.2015.12.3.496-502.

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The present study aimed to explain the dose-dependent possible deleterious effects of 30 day administration of Tramadol on some hematological and biochemical parameters of laboratory male rats (Rattus norvegicus), the study consisted of eighteen adult male rats randomly divided into three equal groups (each of six). Group 1 (control) were treated by intraperitoneal injection of normal saline solution (0.2 ml), group two (low dose) was treated by intraperitonealy (i.p) injection of Tramadol at a dose of 50 mg/kg/day, group three (high dose) was treated by intraperitonealy injection of Tramadol
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48

Petrov, R., A. Valchev, S. Dimitrova, and I. Lazarova. "A study on some basic blood biochemical parameters of Eastern imperial eagles (Aquila heliaca) in Bulgaria." BULGARIAN JOURNAL OF VETERINARY MEDICINE 28, no. 2 (2025): 187–94. https://doi.org/10.15547/bjvm.2023-0115.

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The Eastern imperial eagle (Aquila heliaca) is one of the largest birds of prey in Southeastern Europe. In Bulgaria, the Eastern imperial eagle is critically endangered. The object of this study was to report species-specific values of some basic biochemical parameters in healthy wild and captive birds from the country. Between 2021-2022, nine blood samples were obtained from the species and the values of 18 indicators were determined: alanine transaminase, albumin, alkaline phosphatase, amylase, aspartate transaminase, calcium, chloride, cholesterol, creatine kinase, creatinine, blood glucose
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Oliveira, Denise Silva de, Júlia Matzenbacher dos Santos, Kayorrany Gomes Galvão do Prado, Andreia Vitor Couto Amaral, and Sandra Aparecida Benite-Ribeiro. "EFFECTS OF TYPE 2 DIABETES MELLITUS INDUCTION AND OF MODERATE PHYSICAL EXERCISE ON THE HEPATIC METABOLISM AND OXIDATIVE STRESS IN WISTAR RATS." Revista Contexto & Saúde 20, no. 39 (2020): 55–61. http://dx.doi.org/10.21527/2176-7114.2020.39.55-61.

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AIMS: The aim of the study was to verify if the induction of Type 2 Diabetes Mellitus (T2DM) by the association of streptozotocin and high fat diet causes hepatic alterations and if physical exercise can improve these alterations. METHODS: Forty-six Wistar rats were divided into two groups. One group received a diet containing 60% of fat for 9 weeks and on the 14th day they were injected with a single dose of streptozotocin (25mg/kg). The other group, named control group, received a standard diet and a single dose of citrate buffer was given. Animals were them divided into two subgroups: one s
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50

Ilkiw, Jan E., Philip E. Davis, and David B. Church. "Hematologic, biochemical, blood-gas, and acid-base values in Greyhounds before and after exercise." American Journal of Veterinary Research 50, no. 4 (1989): 583–86. https://doi.org/10.2460/ajvr.1989.50.04.583.

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SUMMARY After racing 722 m, 16 Greyhounds were evaluated to determine changes in hematologic, biochemical, blood-gas, and acid-base values following exercise. Values were determined before racing (T0), immediately after racing (T1), and 3 hours after racing (T2). Significant changes detected immediately after racing included increased heart rate, respiratory rate, and rectal temperature. Significant changes in hematologic values included increases in pcv, total plasma protein, hemoglobin, rbc, wbc, neutrophils, and lymphocytes. Change was not detected in values for monocytes, eosinophils, and
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