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Relevant bibliographies by topics / Aldehyde thiosemicarbazone

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Academic literature on the topic 'Aldehyde thiosemicarbazone'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Aldehyde thiosemicarbazone"

1

P., Verma, K. Arya K., and Ahmad S. "Oxovanadium(Iv), oxomolybdenum(v) and manganese(II) complexes of Schiff bases derived from thiosemicarbazide." Journal of Indian Chemical Society Vol. 83, Apr 2006 (2006): 327–31. https://doi.org/10.5281/zenodo.5835686.

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Department of Chemistry, Bareilly College, Bareilly-243 00 I, Uttar Pradesh, India <em>Manuscript received 28 October 2003, revised 14 November 2005, accepted 2 December 2005</em> Metal complexes formed by the interaction of bis(furfuryl-2-aldehyde) thiosemicarbazonc [FAL TSC], bis(indole-3-aldehyde) thiosemicarbazone [IALTSC], bis(3-methyl salicylaldehyde) thiosemicarbazone [MSALTSC], bis(S-methyl salicylaldehyde) thiosemicarbazone [M'SALTSC] and bis(S-bromo salicylaldehyde) thiosemicarbazone [BSALTSC] with oxovanadium(Iv), oxo·molybdenum(v) and managanese(n) chloride have been pre

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2

Ozturk, I. I. "SYNTHESIS, CHARACTERIZATION AND HIRSHFELD SURFACE ANALYSIS OF SOME THIOSEMICARBAZONES CONTAINING A FIVE-MEMBERED RING." Журнал структурной химии 64, no. 4 (2023): 109673. http://dx.doi.org/10.26902/jsc_id109673.

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Thiosemicarbazones, which are multidentate ligands, are considered as one of the most important classes of organic compounds due to their broad spectrum of pharmacological effects and their ability to coordinate easily with metal ions. Four thiosemicarbazones, furan-2-carbaldehyde-N-methyl thiosemicarbazone (Hfmtsc), thiophene-2-acetaldehyde thiosemicarbazone (Hattsc), thiophene-2-acetaldehyde-N-methyl thiosemicarbazone (Hatmtsc) and thiophene-2-acetaldehyde-N-ethyl thiosemicarbazone (Hatetsc) were successfully prepared via condensation reaction using substituted aldehyde and (un)substituted t

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C., L. JAIN, N. MUNDLEY P. та BAJAJ R. "lron(III), Ruthenium(III), Rhodium(III), PalladiumII), Cobalt(II) and Nickel(II) Complexes with N-(α:-Pyridyl)furfural-2-aldehyde Thiosemicarbazone and N-(α-Pyridyl)thiophene· 2-aldehyde Thiosemicarbazone". Journal of Indian Chemical Society Vol. 69, Nov 1992 (1992): 777–79. https://doi.org/10.5281/zenodo.6044089.

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Department of Chemistry, M. M. H. College, Ghaziabad-201 001<strong> </strong> <em>Manuscript received 10 May </em><em>1991, revised 20 July 1992, accepted 31 July 1992</em> lron(III), Ruthenium(III), Rhodium(III), PalladiumII), Cobalt(II) and Nickel(II) Complexes with N-(α:-Pyridyl)furfural-2-aldehyde Thiosemicarbazone and N-(α-Pyridyl)thiophene· 2-aldehyde Thiosemicarbazone.

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4

Shehzad, Muhammad Tariq, Ajmal Khan, Sobia Ahsan Halim, et al. "Synthesis of indole-substituted thiosemicarbazones as an aldose reductase inhibitor: an in vitro, selectivity and in silico study." Future Medicinal Chemistry 13, no. 14 (2021): 1185–201. http://dx.doi.org/10.4155/fmc-2020-0060.

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Aim: Indole is an important component of many drug molecules, and its conjugation with thiosemicarbazone moiety would be advantageous in finding lead compounds for the development of diabetic complications. Methodology: We have designed, synthesized and evaluated a series of 17 indole-thiosemicarbazones (3a–q) as aldose reductase (ALR2) and aldehyde reductase (ALR1) inhibitors. Results: After in vitro evaluation, all indole-thiosemicarbazones showed significant inhibition against both enzyme ALR1 and ALR2 with IC50 in range of 0.42–20.7 and 1.02–19.1 μM, respectively. The docking study was als

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Wakodkar, Rohit R., Mazahar Farooqui, Pravin Kulkarni, and Deepak D. Kayande. "Synthesis and Biological Activity of Some Thiosemicarbazide." Asian Journal of Organic & Medicinal Chemistry 4, no. 4 (2019): 228–31. http://dx.doi.org/10.14233/ajomc.2019.ajomc-p206.

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In this paper, thiosemicarbazone derivatives have been prepared from substituted aromatic aldehyde and thiosemicarbazide in presence of sodium chloride. This method is an efficient, mild, inexpensive, non-toxic and environment benign catalyst. This protocol includes the reaction followed by using sodium chloride to accelerate the reaction in aqueous ethanol. The structure of synthesized compounds were determined by IR, 1H NMR, 13C NMR and mass spectroscopies as well as the compounds were also screened for antibacterial and antifungal activity against certain Gram-negative and Gram-positive bac

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6

Dang, Tran Buu, Le Chi Hien Dat, Vu Tuan Huy, Nguyen Minh Phuong, and Duong Ba Vu. "Salicylic aldehyde-n(4)-(4-ethoxyanilinyl) thiosemicarbazone: optimization of synthesis by surface response and structural characteristics." Tạp chí Khoa học 16, no. 6 (2019): 5. http://dx.doi.org/10.54607/hcmue.js.16.6.2514(2019).

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Salicylic aldehyde-N(4)-(4-ethoxyanilinyl)thiosemicarbazone (H2L) was synthesized by condensation between salicylic aldehyde (SA) and N(4)-(4-ethoxyanilinyl)thiosemicarbazide (TSCZ) in presence of glacial acetic acid as a homogeneous catalyst in ethanol. As a result of analysis by the surface response based on Box – Hunter model with the confidence level of 95%, the expectable yield reached the highest point (around 68%) at 80oC for 10 minutes when approximately 1 mole of SA reacted to equivalently 1 mole of TSCZ. The structure of H2L was solved by IR, UV-Vis, 1H and 13C NMR, HSQC, HMBC and HR

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Verma, K. K., N. Nirwan, R. Singh, and N. Bhojak. "Microwave Assisted Synthesis, Characterisation and Biological Activities of Cu(II) Complexes of Few Thiosemicarbazones Ligands." Journal of Scientific Research 15, no. 1 (2023): 275–83. http://dx.doi.org/10.3329/jsr.v15i1.60772.

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Thiosemicarbazones are class of compounds which are obtained by the condensation of thiosemicarbazide with carbonyl compounds. The transition metal complexes of thiosemicarbazones are widely considered due to their broad spectrum of biological activities such as antibacterial, antitumor and antifungal activities. In present research work a series of four novel Cu(II) aryl thiosemicarbazones complexes having the general composition [Cu(L1)2Cl2], [Cu(L2)2Cl2], [Cu(L3)2Cl2] and [Cu(L4)2Cl2]{where L1= 4-nitroacetophenone thiosemicarbazones (4NAT), L2 = 3-nitrobenzaldehyde thiosemicarbazone (3NBT),

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8

Rusnac, Roman, Andrei Ciursin, Sergiu Shova, Angela Sirbu, and Aurelian Gulea. "Synthesis and physical-chemical analysis of the coordination compounds of Cu(II) based on 3-ethoxysalicylaldehyde 4-cyclohexyl-thiosemicarbazone." Studia Universitatis Moldaviae. Seria Științe ale Naturii, no. 1(171) (September 2023): 194–205. http://dx.doi.org/10.59295/sum1(171)2023_26.

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In this article, methods of synthesis and physicochemical analysis of 5 coordination compounds based on Cu(II) ion and 3-ethoxysalicylic aldehyde 4-cyclohexyl-thiosemicarbazone are described. In the first step, the synthesis of the ligand was carried out by means of two classical methods with subsequent refinement, thus obtaining the H2L as a chelator of copper(II) ions. 1H, 13C and 15N-NMR spectroscopy, 13C-DEPT-135 NMR and 15N HSQC-NMR spectroscopy were applied to investigate the structure and geometry of the 3-ethoxysalicylic aldehyde 4-cyclohexyl-thiosemicarbazone. The synthesized substanc

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P., UMAPATHY, P. BUDHKAR A., and S. DORAI C. "Synthesis and Spectral Studies on Metal Chelates of Heterocyclic Carboxaldehyde Thiosemicarbazones." Journal of Indian Chemical Society Vol. 63, Aug 1986 (1986): 714–21. https://doi.org/10.5281/zenodo.6295026.

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National Chemical Laboratory, Poona-411 008 <em>Manuscript received 18 September 1984, </em>revised <em>16 August 1985, accepted 12 August 1986</em> Square-planar neutral metal chelates of aldehyde thiosemicarbazones of the type ML,. where M=Ni<sup>II</sup>, Pd<sup>lI</sup> or Pt<sup>II</sup> and HL =thiosemicarbazone or 4-phenyl- or 4-methytthlosemicarbazone of 2-furaldehyde or thiopbene-2-carboxaldehyde or <em>o</em>-nitrobenzaldehyde. have been synthesised and characterised. Jr. uv-visible. <sup>1</sup>H and <sup>13</sup>C nmr and polarographic techniques have been utilised t

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G., Valli, Sivakolunthu S., Muthusubramanian S., and Sivasubramanian S. "Synthesis and biological activity of copper(II) mixed ligand complexes with thiophene-2-aldehyde thiosemicarbazone as the primary ligand." Journal of Indian Chemical Society Vol. 77, May 2000 (2000): 252–53. https://doi.org/10.5281/zenodo.5868022.

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School of Chemistry. Madurai Kamaraj University, Madurai-625 021, India Department of Chemistry, S. F. R. College for Women, Sivakasi-626 123, India <em>Manuscript received 25 November 1999. revised 27 January 2000. accepted 11 February 2000</em> The complexing ability of thiophene-2-aldehyde thiosemicarbazone (L) has been investigated. Copper complexes of the type CuLL<sub>1</sub> have been prepared, where L<sub>1</sub> = salicylaldehyde/salicylaldoximelsalicylaldehyde semicarbazone/salicylaldehyde phenylhydrazone/ salicylaldehyde thiosemicarbazone/8-hydroxyquinoline/2-hydroxypyridine. The co

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Book chapters on the topic "Aldehyde thiosemicarbazone"

1

Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) complex with thiophene-2-aldehyde thiosemicarbazone." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_284.

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2

Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) mixed ligand complex with thiophene-2-aldehyde thiosemicarbazone and salicylaldehyde." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_285.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) mixed ligand complex with thiophene-2-aldehyde thiosemicarbazone and salicylaldoxime." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_286.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) mixed ligand complex with thiophene-2-aldehyde thiosemicarbazone and salicylaldehyde phenylhydrazone." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_287.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) mixed ligand complex with thiophene-2-aldehyde thiosemicarbazone and salicylaldehyde semicarbazone." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_288.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) mixed ligand complex with thiophene-2-aldehyde thiosemicarbazone and 2-hydroxypyridine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_291.

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7

Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) mixed ligand complex with thiophene-2-aldehyde thiosemicarbazone and salicylaldehyde thio-semicarbazone." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_289.

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8

Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) mixed ligand complex with thiophene-2-aldehyde thiosemicarbazone and 8-hydroxy quinoline." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_290.

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9

Rusnac, Anna, G. Balan, and A. Gulea. "Coordination Compounds of Cu(II), Ni(II) Based on Ethyl 4-Benzoate Thiosemicarbazons Derivatives of Salicyl Aldehyde. Antimicrobial and Antifungal Properties." In IFMBE Proceedings. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-92328-0_80.

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Conference papers on the topic "Aldehyde thiosemicarbazone"

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Guliyeva, Lala, Muhammed Trawally, Kübra Demir-Yazıcı, Kerem Kaya, Atilla Akdemir, and Özlen Güzel-Akdemir. "Thione or Thiol: Sructural Confirmation of (E)-2-(1-(4-cyanophenyl)ethylidene)-N-(2-fluoro-4-sulfamoylphenyl)hydrazine-1-Carbothioamide and Carbonic Anhydrase Inhibition Studies." In 8th International Students Science Congress. ULUSLARARASI ÖĞRENCİ DERNEKLERİ FEDERASYONU (UDEF), 2024. https://doi.org/10.52460/issc.2024.060.

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Thiosemicarbazones are Schiff bases formed by condensing an aldehyde or ketone with thiosemicarbazide derivatives. TSCs exhibit various biological activities and act as precursors for key scaffolds, with keto-enol tautomerism commonly resulting in thione or thiol forms. This study focuses on synthesizing and confirming the structure of compound 1, (E)-2-(1-(4-cyanophenyl)ethylidene)-N-(2-fluoro-4-sulfamoylphenyl)hydrazine-1-carbothioamide, through a condensation reaction in methanol. Both theoretical and experimental IR and X-ray studies confirm the presence of the thione form and E isomerism.

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Birca, Maria, Roman Rusnac, and Aurelian Gulea. "Iron(III) coordination compound with some n(4) -substituted thiosemicarbazones of salicyl aldehyde and cinnamic aldehyde derivatives." In Conferința științifică națională cu participare internațională "Integrare prin cercetare și inovare", dedicată Zilei Internaționale a Științei pentru Pace și Dezvoltare. Moldova State University, 2025. https://doi.org/10.59295/spd2024n.71.

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In this paper, the purpose of synthesis of Fe(III) coordination compounds with some N(4)-substituted thiosemicarbazones of salicyl aldehyde and cinnam aldehyde derivatives was pursued: which contain as a radical in the N(4) position: tert-butyl, cyclohexyl; allyl, methyl. The structure of thiosemicarbazones HnL1-5 was confirmed by FTIR spectroscopy and TLC analysis, melting point and NMR spectra. Based on the above-mentioned ligands, 5 coordination combinations were obtained, the research of which was carried out with the help of infrared spectroscopy. All synthesized compounds are being resea

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Zhupikova, O. A., O. I. Yarovaya, M. K. Marenina, et al. "SYNTHESIS OF THIOSEMICARBOSONES WITH ACTIVITY AGAINST SARS-COV-2 AND H1N1 INFLUENZA VIRUSES." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-185.

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In this work, new thiosemicarbazones were synthesized based on the corresponding heterocyclic aldehydes and their antiviral properties were studied. The substances were obtained as colored solids in yields ranging from 82 to 94 %. It has been shown that 2-((5-(p-tolyl)isoxazol-3-yl)methylene)hydrazine-1-carbothiamide exhibits activity against SARS-CoV-2 and H1N1 influenza viruses in the micromolar range and is not toxic on the tested cell lines.

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