Academic literature on the topic 'Aldosteronism'

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Dissertations / Theses on the topic "Aldosteronism"

1

Ronconi, Vanessa. "The cardiometabolic syndrome in primary aldosteronism: role of adipose tissue." Doctoral thesis, Università Politecnica delle Marche, 2010. http://hdl.handle.net/11566/242153.

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2

Kohmo, Kyoko. "Adrenal reserve function after unilateral adrenalectomy in patients with primary aldosteronism." Kyoto University, 2015. http://hdl.handle.net/2433/200439.

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3

Donà, Gabriella. "Human red blood cells alterations in Primary Aldosteronism: Mineralocorticoid Receptor (MR) involvement in the Aldosterone pathway." Doctoral thesis, Università degli studi di Padova, 2015. http://hdl.handle.net/11577/3423923.

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Red blood cells (RBCs) are a-nucleated cells particularly exposed to different stimuli, among which circulating hormones and intra/extra-cellular derivatives from oxidization processes. In addition, our previous studies showed that in the case of inflammatory diseases with GSH content alterations, RBCs were much more sensitive to diamide, a mild oxidant able to trigger tyrosine-phosphorylation (Tyr-P) of membrane proteins, mainly band 3. Aldosterone (Aldo), mineralocorticoid hormone, has been shown to induce many effects other than the common diuretic process regulation and involving the exp
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4

Aldighieri, Enrico. "Human primary aldosteronism; investigation of the mechanism leading to autonomous aldosterone excess." Doctoral thesis, Università degli studi di Padova, 2008. http://hdl.handle.net/11577/3421768.

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Objective: Due to its unique expression of aldosterone synthase cytocromo P450 (CYP11B2), the enzyme required for the final steps of aldosterone biosynthesis aldosterone is exclusively expressed in the adrenalcortical zona glomerulosa cell. Some studies suggested that the CYP11B2 gene expression can be higher in APAs than in normal adrenocortical tissues, leading to postulate a transcriptional modulation of aldosterone overproduction in these tumors but antibodies capable to identify this protein do not exist. Thus we performed studies of in-situ hybridization (ISH) to analyze CYP11B2 localiza
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5

MacConnachie, Alisdair A. "Investigation of the prevalence and genetic characterisation of patients with glucocorticoid remediable aldosteronism." Thesis, University of Aberdeen, 1997. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU528796.

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After the elucidation of the underlying genetic cause in many Mendellian diseases molecular medicine has turned its attention to the more common polygenic disorders. High blood pressure is one such complex trait which has been the subject of much interest in recent years. A number of candidate loci have been found to different groups to influence blood pressure and have been implicated in the aetiology of essential hypertension although the most significant discoveries have been in the single gene causes of high blood pressure. Glucocorticoid remediable aldosteronism (GRA) is an autosomal domi
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6

Csonka, Enikö. "Method verification for aldosterone and renin assay - a reliable screening test for primary aldosteronism." Thesis, Uppsala universitet, Forskargrupper (Inst. för kvinnor och barns hälsa), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-358217.

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Primary aldosteronism (PA) is a common form of secondary hypertension with an international prevalence rates between 5 and 10 %. It is characterized by a high autonomous aldosterone production that causes cardiovascular damage, renin suppression, hypertension, sodium retention, potassium excretion and hypokalemia. The screening of PA is a simple test measuring aldosterone to renin ratio (ARR) with immunoassay method. This test is currently considered as the most reliable screening tool for PA.     The main objective of the study was to evaluate an ELISA-method, for detection of aldosterone an
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7

ZHU, RUI. "Simplification of the diagnostic work-up of primary aldosteronism and investigation of immunology mechanisms." Doctoral thesis, Università degli studi di Padova, 2022. http://hdl.handle.net/11577/3443120.

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Background Primary aldosteronism (PA) is the most common cause of arterial hypertension characterized by high levels of aldosterone, resulting in excessive mineralocorticoid receptor (MR) stimulation, and extensive hypertensive-mediated organ damage (HMOD). Current guidelines recommend one or more exclusion tests in patients performed the screening test with the measurement of aldosterone-to-renin ratio (ARR) to avoid further lateralization procedures in those who tested false-positive. To date the diagnostic gain provided by these exclusion tests over the ARR was examined only in few studie
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8

Citton, Marilisa. "Effect of unilateral adrenalectomy on the quality of life of patients with lateralized primary aldosteronism." Doctoral thesis, Università degli studi di Padova, 2016. http://hdl.handle.net/11577/3422284.

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Background. Previous studies reported that primary aldosteronism (PA) is associated with an increased prevalence of anxiety, depression and subnormal quality of life (QoL) scores that may be improved after surgical treatment. Aim of the Study. The aim of the study was to assess the impact of surgery on health-related QoL and depression status of patients suffering from PA, comparing the results with a control group of patients undergoing surgery for a non-secreting adrenal tumor. Materials and Methods. Data on QoL and depression status were prospectively collected, from January 2014 to Oct
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9

Reimer, Esther [Verfasser], Ute [Gutachter] Scholl, and Christoph [Gutachter] Fahlke. "Investigations of somatic and germline mutations in primary aldosteronism / Esther Reimer ; Gutachter: Ute Scholl, Christoph Fahlke." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2018. http://d-nb.info/1152076280/34.

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10

Ohno, Youichi. "Prevalence of Cardiovascular Disease and Its Risk Factors in Primary Aldosteronism: A Multicenter Study in Japan." Kyoto University, 2019. http://hdl.handle.net/2433/242409.

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