Academic literature on the topic 'Alkaloid synthesis'

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Journal articles on the topic "Alkaloid synthesis"

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Han, Sunkyu, Sangbin Jeon, and Joonoh Park. "Syntheses of Dimeric Securinega Alkaloids." Synlett 28, no. 18 (2017): 2353–59. http://dx.doi.org/10.1055/s-0036-1590864.

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The isolation of flueggenines A and B by Yue and co-workers in 2006 has triggered a burst of isolation reports of dimeric and oligomeric securinega alkaloid natural products. The compelling molecular structures of these compounds with various modes of connection between monomeric securinega units have posed intriguing challenges to the synthetic organic community. Herein, we have categorized high-order securinega alkaloids based on their biosynthetic mode of dimerization or oligomerization. We then have compiled all reported syntheses of dimeric securinega alkaloids based on our classification
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Dewan, S. Bhakuni. "Biosynthesis and synthesis of biologically active alkaloids of Indian medicinal plants." Journal of Indian Chemical Society Vol. 79, Mar 2002 (2002): 203–10. https://doi.org/10.5281/zenodo.5840849.

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Central Drug Research Institute, Lucknow-226 001, India <em>E-mail :</em>Root@cdrilk.Sirnetd.ernet.in&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp;&nbsp;<em>Fax : </em>91-0522-223405/223938 The structure and stereochemistry of biologically active alkaloids isolated from <em>Croton sparsiflorus, Cocculus laurifolius, C. pendulus, Corydalis meifolia </em>and <em>Stephania glabra </em>were established. Biosynthetic studies were carried out on proaporphine and dihydroproaporphgne alkaloids, crotsparine and crotsparinine, and abnormal aporphine alkaloid sparsiflorine; abnor&shy;mal <em>Eryt
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Enders, Dieter, and Christoph Thiebes. "Efficient stereoselective syntheses of piperidine, pyrrolidine, and indolizidine alkaloids." Pure and Applied Chemistry 73, no. 3 (2001): 573–78. http://dx.doi.org/10.1351/pac200173030573.

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Recent advances in the diastereo- and enantioselective synthesis of piperidine, pyrrolidine, and indolizidine alkaloids, based on the highly stereoselective 1,2-addition to the CN double bond of chiral aldehyde-SAMP/RAMP hydrazones, are described. The enantioselective syntheses of the pyrrolidine alkaloids bgugaine and (2S,12¢R)-2-(12¢-aminotridecyl)-pyrrolidine, a defense alkaloid of the Mexican bean beetle are reported. Furthermore, the SAMP/RAMP-hydrazone method was applied to the syntheses of two 5,8-disubstituted indolizidine alkaloids that have been extracted from neotropical poison-dart
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Giannis, Athanassios, Farnoush Mousavizadeh, and Daniel Meyer. "Synthesis of C-Nor-D-homo-steroidal Alkaloids and Their Derivatives." Synthesis 50, no. 08 (2018): 1587–600. http://dx.doi.org/10.1055/s-0036-1591965.

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The C-nor-D-homo-steroidal alkaloid cyclopamine was discovered in the 1969 and in 2000 it was shown to act as an inhibitor of the hedgehog signaling (Hh) pathway, which is aberrantly activated in some tumors. Subsequently it was revealed that this natural occurring alkaloid has also antidiabetic and antiviral properties. In this review we present syntheses of selected C-nor-D-homo-steroidal alkaloids and their analogues and also discuss a general access to C-nor-D-homo-steroids. Some historical as well as biomedical aspects are also presented.1 Introduction2 Total Synthesis of Cyclopamine2.1 S
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Zhang, Ye, Lei Zhang, and Xiangbing Qi. "Total Synthesis of (–)-Alstofolinine A: Selected Furan Oxidation/ Cyclization Cascade." Synlett 31, no. 01 (2019): 7–12. http://dx.doi.org/10.1055/s-0039-1690247.

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Indole-fused tetracyclic ring systems containing nitrogen atoms are common core skeletons of many indole alkaloids such as sarpagine, macroline, and ajmaline. Efficient and stereoselective construction of these ring systems can promote the development of the corresponding alkaloid syntheses. In this article, we briefly summarize our current progress toward the application of the aza-Achmatowicz reaction and indole nucleophilic addition reaction cascade for the first asymmetric total synthesis of the macroline-type indole alkaloid (–)-Alstofolinine A. Our synthetic strategy is based on furan ox
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Wink, Michael, and Ludger Witte. "Cell-Free Synthesis of the Alkaloids Ammodendrine and Smipine." Zeitschrift für Naturforschung C 42, no. 3 (1987): 197–204. http://dx.doi.org/10.1515/znc-1987-0304.

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The bipiperidyl alkaloid ammodendrine was detected in 28 plant species as a minor alkaloid besides quinolizidine alkaloids. Cadaverine serves as a precursor for both quinolizidine alkaloids and for ammodendrine, since labelled cadaverine is incorporated into both rings of ammoden­drine. Cell-free extracts of Lupinus arboreus and of Pisum sativum, which contain an active diamine oxidase form ammodendrine from cadaverine and pyruvate. In addition to ammoden­drine other alkaloids such as smipine, tetrahydroanabasine and tripiperideine could be detected. Possible reaction schemes are discussed.
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Chen, Bi-Shuang, Di Zhang, Fayene Zeferino Ribeiro de Souza, and Lan Liu. "Recent Advances in the Synthesis of Marine-Derived Alkaloids via Enzymatic Reactions." Marine Drugs 20, no. 6 (2022): 368. http://dx.doi.org/10.3390/md20060368.

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Alkaloids are a large and structurally diverse group of marine-derived natural products. Most marine-derived alkaloids are biologically active and show promising applications in modern (agro)chemical, pharmaceutical, and fine chemical industries. Different approaches have been established to access these marine-derived alkaloids. Among these employed methods, biotechnological approaches, namely, (chemo)enzymatic synthesis, have significant potential for playing a central role in alkaloid production on an industrial scale. In this review, we discuss research progress on marine-derived alkaloid
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Li, Yong, Jian Li, Hanfeng Ding, and Ang Li. "Recent advances on the total synthesis of alkaloids in mainland China." National Science Review 4, no. 3 (2017): 397–425. http://dx.doi.org/10.1093/nsr/nwx050.

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AbstractAlkaloids are a large family of natural products that mostly contain basic nitrogen atoms. Because of their intriguing structures and important functions, they have long been popular targets for synthetic organic chemists. China's chemists have made significant progress in the area of alkaloid synthesis over past decades. In this article, selected total syntheses of alkaloids from research groups in mainland China during the period 2011–16 are highlighted.
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D’hooghe, Matthias, Hyun-Joon Ha, and Lingamurthy Macha. "Deployment of Aziridines for the Synthesis of Alkaloids and Their Derivatives." Synthesis 51, no. 07 (2019): 1491–515. http://dx.doi.org/10.1055/s-0037-1611715.

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Various (activated and non-activated) aziridines with diverse substitution patterns have been deployed successfully as starting materials for the synthesis of a wide variety of alkaloids via suitable functionalization and aziridine ring transformation. Alternatively, the preparation and interception of reactive aziridine intermediates has also been shown to constitute a valid approach toward alkaloid synthesis. This review summarizes aziridine-mediated syntheses of alkaloids, in which the aziridine is mobilized as either a substrate or an advanced synthetic intermediate.1 Introduction2 Alkaloi
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Ryan, Suzanne M., Kathleen D. DeBoer, and John D. Hamill. "Alkaloid production and capacity for methyljasmonate induction by hairy roots of two species in Tribe Anthocercideae, family Solanaceae." Functional Plant Biology 42, no. 8 (2015): 792. http://dx.doi.org/10.1071/fp15045.

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In addition to producing medicinally important tropane alkaloids, some species in the mainly Australian Solanaceous tribe Anthocercideae, sister to genus Nicotiana, are known to also contain substantial levels of the pyridine alkaloids nicotine and nornicotine. Here, we demonstrate that axenic hairy root cultures of two tribe Anthocercideae species, Cyphanthera tasmanica Miers and Anthocercis ilicifolia ssp. ilicifolia Hook, contain considerable amounts of both nicotine and nornicotine (~0.5–1% DW), together with lower levels of the tropane alkaloid hyoscyamine (&lt;0.2% DW). Treatment of grow
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Dissertations / Theses on the topic "Alkaloid synthesis"

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Mathews, C. J. "Alkaloid synthesis." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238202.

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Atkinson, Jonathan D. M. "Alkaloid synthesis." Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302885.

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Ali, Naji M. "Studies in alkaloid synthesis." Thesis, University of East Anglia, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327933.

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Callaghan, Owen. "Synthetic and mechanistic studies in free radical." Thesis, University of Strathclyde, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366957.

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Murphy, James P. "Synthesis of azabicyclic intermediates for alkaloid synthesis." Thesis, Queen's University Belfast, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394528.

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Boynton, Carole M. "Alkaloid synthesis via novel azabicycles." Thesis, Sheffield Hallam University, 1988. http://shura.shu.ac.uk/19384/.

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A basic introduction to pyrrolizidine and indolizidine alkaloids has been described along with a selection of recent syntheses of the said compounds. Cycloalkene synthesis by intramolecular Wittig reaction has been reviewed and we describe the utility of this strategy in the formation of nitrogen-bridgehead bicycles which can then be used in alkaloid synthesis. Our initial studies on the viability of this strategy in the synthesis of fused pyrrolidone systems employed a Wittig reaction between 5-acetylpyrrolidin-2-one and vinylphosphonium salts. A comparison was made between three different vi
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Antropow, Alyssa Hope. "Synthesis and anticancer evaluation of agelastatin alkaloid derivatives and enantioselective total synthesis of aspidosperma alkaloids." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/118214.

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Thesis: Ph. D. in Organic Chemistry, Massachusetts Institute of Technology, Department of Chemistry, 2018.<br>Cataloged from PDF version of thesis. Vita.<br>Includes bibliographical references.<br>I. Synthesis and Evaluation of Agelastatin Derivatives as Potent Modulators for Cancer Invasion and Metastasis The synthesis of new agelastatin alkaloid derivatives and their anticancer evaluation in the context of the breast cancer microenvironment is described. A variety of Ni -alkyl and C5-ether agelastatin derivatives were accessed via application of our strategy for convergent imidazolone synthe
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Lam, Kwun Ting. "Chiral acetylenic sulfoxide in asymmetric alkaloid synthesis." HKBU Institutional Repository, 2004. http://repository.hkbu.edu.hk/etd_ra/509.

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Bennett, P. A. R. "Synthetic approaches to the alkaloid himbacine." Thesis, University of Oxford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233479.

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Börger, Carsten, Micha P. Krahl, Margit Gruner, Olga Kataeva, and Hans-Joachim Knölker. "First total synthesis of the biscarbazole alkaloid oxydimurrayafoline." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-139201.

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We report the first total synthesis of oxydimurrayafoline via nucleophilic substitution at the benzylic position at C-3 of the carbazole framework<br>Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich
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Books on the topic "Alkaloid synthesis"

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Knölker, Hans-Joachim, ed. Alkaloid Synthesis. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-25529-8.

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Ali, Naji M. Studies in alkaloid synthesis. University of East Anglia, 1989.

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Ouali, Dehimi. Enantioselective synthesis of novel Corynanthe indole alkaloid synthons. University of Salford, 1991.

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Owen, David Alan. Aryl substituted cyclohexadienyl iron complexes in alkaloid synthesis. University of East Anglia, 1990.

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Pettersson-Fasth, Helena. Preparation and functionalization of 4-(p-toluenesulfonamido)-2-alken-1-ol derivatives, and their use in alkaloid synthesis. Acta Universitatis Upsaliensis, 1994.

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Armitage, Mark Alan. Studies in asymmetric synthesis: Attempted asymmetric reformatsky reactions & approaches towards the alkaloid fastigiatine. University of East Anglia, 1993.

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Karvinen, Esko. Indolo[2,3-a]quinolizidine derivatives: New methods of preparation and a synthesis of the indole alkaloid (+)-eburnamonine. Suomalainen Tiedeakatemia, 1992.

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1900-, Mothes Kurt, Schütte Horst Robert, Luckner Martin, and Böhm H, eds. Biochemistry of alkaloids. VCH, 1985.

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Matsuoka, Junpei. Total Synthesis of Indole Alkaloids. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-8652-1.

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Mo, Ruowei. Towards the enantioselective synthesis of lycoricidine alkaloids. Brock University, Dept. of Chemistry, 1998.

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Book chapters on the topic "Alkaloid synthesis"

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Ohno, Hiroaki, Norihito Arichi, and Shinsuke Inuki. "Nonbiomimetic Total Synthesis of Polycyclic Alkaloids." In Modern Natural Product Synthesis. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-1619-7_19.

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AbstractIn nonbiomimetic natural product synthesis, there are no restrictions on the design of synthetic routes; however, the feasibility of the planned routes is often completely unknown. To discover more efficient and creative syntheses of natural products, and to identify bioactive natural product derivatives that have never been synthesized in nature, our group is engaged in the nonbiomimetic total synthesis of indole alkaloids. In this chapter, we describe our nonbiomimetic total syntheses of quinocarcin, dictyodendrins A–F, and zephycarinatines C and D, by employing alkyne-based approach
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Stevens, R. V. "Alkaloid Synthesis." In Total Synthesis of Natural Products. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470129661.ch3.

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Castedo, L., and E. Guitián. "Isoquinoline Alkaloid Synthesis via Arynes." In Natural Products Chemistry III. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-74017-6_12.

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Lindel, Thomas, Nils Marsch, and Santosh Kumar Adla. "Indole Prenylation in Alkaloid Synthesis." In Topics in Current Chemistry. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/128_2011_204.

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Wink, Michael, and Margaret F. Roberts. "Compartmentation of Alkaloid Synthesis, Transport, and Storage." In Alkaloids. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4757-2905-4_10.

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Sarpong, Richmond, and Daniel F. Fischer. "Total Synthesis of the Lycopodium Alkaloid Complanadine A." In Total Synthesis of Natural Products. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-34065-9_11.

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Ninomiya, Ichiya. "Recent Progress in Our Indole Alkaloid Synthesis." In Natural Products Chemistry III. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-74017-6_10.

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Nakagawa, Masako, Toshiaki Nagata, Koji Ono, et al. "Recent Developments in Marine Indole Alkaloid Synthesis." In Advances in Experimental Medicine and Biology. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0135-0_70.

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Bur, Scott, and Albert Padwa. "Ammonium Ylides as Building Blocks for Alkaloid Synthesis." In Modern Tools for the Synthesis of Complex Bioactive Molecules. John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118342886.ch13.

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Vázquez-Flota, Felipe A. "Alkaloid Synthesis in In Vitro Cultures of Catharanthus Roseus: Potential and Limitations." In Compendium of Plant Genomes. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-89269-2_5.

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Conference papers on the topic "Alkaloid synthesis"

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Klöwer, J. "High Temperature Corrosion by Deposits of Alkali Salts." In CORROSION 1996. NACE International, 1996. https://doi.org/10.5006/c1996-96173.

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Abstract In order to understand and predict how corrosion behaviour of metallic high temperature materials is affected by deposits of alkali salts, eight commercial high temperature alloys (AISI 314, alloy 800H, alloy 31, AC66, alloy 45-TM, alloy 625, alloy 59 and alloy C-4) coated with alkali sulphates and chlorides (Na2SO4/KCl) were investigated in both air and in HCl/SO2- containing waste incineration environments. The corrosion rates were found to depend sensitively on the alloy composition, especially on the concentration of molybdenum and silicon. Both stainless steels and nickel base al
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Sabadash, Vira, Oleh Konovalov, Anna Nowik-Zajac, and Iwona Zawierucha. "Adsorption Properties of Natural and Synthetic Zeolites for Ammonium and Phosphate Removal from Wastewater." In 8th International Congress "Environment Protection. Energy Saving. Sustainable Environmental Management". Trans Tech Publications Ltd, 2025. https://doi.org/10.4028/p-p0hfsd.

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Water resources are crucial in any region's overall natural resource complex. This research focuses on addressing these pollution issues through water treatment processes. The primary objective of this study was to examine the adsorption of phosphates using both natural and synthetic adsorbents, particularly aluminosilicates. Under static and dynamic conditions, the research assessed the sorption characteristics of natural zeolite, specifically clinoptilolite obtained from the Sokyrnytsia mineral deposits. Results indicated that the adsorption of phosphates is more effective in acidic environm
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Rossini, Allan F. C., and Cristiano Raminelli. "Study toward the convergent total synthesis of the aporphine alkaloid PO-3." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_201392135541.

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Muraca, Ana Carolina A., and Cristiano Raminelli. "Study toward the total synthesis of lysicamine: an aporphine alkaloid with antileishmanial activity." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_201395203139.

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Klochkov, S. G., M. E. Neganova, S. A. Pukhov, and E. S. Dubrovskaya. "Stereospecific synthesis of tryptamine derivatives of alkaloid securinine and their potential neuroprotective activity." In PROCEEDINGS OF THE 3RD INTERNATIONAL CONFERENCE ON AUTOMOTIVE INNOVATION GREEN ENERGY VEHICLE: AIGEV 2018. Author(s), 2019. http://dx.doi.org/10.1063/1.5087358.

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Wipf, Peter, and Filip Petronijevic. "New Approaches to Indoles and Indole Alkaloids." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0388-1.

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Sarpong, Richmond. "Strategies and Tactics for Synthesis Inspired by Complex Alkaloids." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-speech7.

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Gao, Kai, Wendong Feng, Xiaojun Yan, Xiaobin Guo, Xiaoyan Cui, and Xiliang Guo. "High Efficient Mineralization of Cesium in Waste Liquid by Hydrothermal Method." In 2022 29th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/icone29-90716.

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Abstract During the nuclear fuel cycle, a large amount of radioactive cesium is produced, and at the same time, it is difficult to safely dispose of because of its extremely soluble in water and low boiling point. The safe disposal of radioactive cesium is a problem that needs to be solved urgently. The currently used methods to treat cesium-containing wastewater such as cement fixation, glass solidification and ion exchange, have certain drawbacks, and urgently need to be further optimized. Pollucite is an analcite molecular sieve. Many studies have shown that it is one of the potential final
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Bertonha, Ariane F., and Antonio C. B. Burtoloso*. "Studies aiming the synthesis of the indolizidine alkaloids (+)-Ipalbidine and (+)-Antofine." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_201391415130.

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Seijas, Julio, M. Vázquez-Tato, Javier Seijo-Muras, Pablo Ramil-Rego, and M. Buján. "Alkaloids from Narcissus bulbocodium L." In The 8th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2004. http://dx.doi.org/10.3390/ecsoc-8-01978.

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Reports on the topic "Alkaloid synthesis"

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Veilleux, Richard E., Jossi Hillel, A. Raymond Miller, and David Levy. Molecular Analysis by SSR of Genes Associated with Alkaloid Synthesis in a Segregating Monoploid Potato Family. United States Department of Agriculture, 1994. http://dx.doi.org/10.32747/1994.7570550.bard.

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More than 15,000 anthers of an interspecific hybrid (CP2) between two diploid (2n=2x=24) potato species, Solanum chacoense (weedy) and S. phureja (cultivated), were cultured to generate a family of monoploid (haploid, 2n-1x=12) plants. Of 260 regenerated plants, 34 were monoploid, 210 diploid and 16 tetraploid. SSR analysis revealed that six monoploids were genetically identical and 14 diploids were homozygous, thus limiting the population to 42 (28 monoploids and 14 homozygous diploids). New microsatellite loci were developed for potato from database sequences (15), a conventional genomic lib
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Corriveau, L., J. F. Montreuil, O. Blein, et al. Metasomatic iron and alkali calcic (MIAC) system frameworks: a TGI-6 task force to help de-risk exploration for IOCG, IOA and affiliated primary critical metal deposits. Natural Resources Canada/CMSS/Information Management, 2021. http://dx.doi.org/10.4095/329093.

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Australia's and China's resources (e.g. Olympic Dam Cu-U-Au-Ag and Bayan Obo REE deposits) highlight how discovery and mining of iron oxide copper-gold (IOCG), iron oxide±apatite (IOA) and affiliated primary critical metal deposits in metasomatic iron and alkali-calcic (MIAC) mineral systems can secure a long-term supply of critical metals for Canada and its partners. In Canada, MIAC systems comprise a wide range of undeveloped primary critical metal deposits (e.g. NWT NICO Au-Co-Bi-Cu and Québec HREE-rich Josette deposits). Underexplored settings are parts of metallogenic belts that extend in
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