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Relevant bibliographies by topics / Alkyl-quinolones

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Journal articles

Academic literature on the topic 'Alkyl-quinolones'

Author: Grafiati

Published: 25 May 2024

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Journal articles on the topic "Alkyl-quinolones"

1

Liu, Huanhuan, Huadan Liu, Enhua Wang, et al. "Hydrogen Bond Assisted Three-Component Tandem Reactions to Access N-Alkyl-4-Quinolones." Molecules 28, no. 5 (2023): 2304. http://dx.doi.org/10.3390/molecules28052304.

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Hydrogen-bonding catalytic reactions have gained great interest. Herein, a hydrogen-bond-assisted three-component tandem reaction for the efficient synthesis of N-alkyl-4-quinolones is described. This novel strategy features the first proof of polyphosphate ester (PPE) as a dual hydrogen-bonding catalyst and the use of readily available starting materials for the preparation of N-alkyl-4-quinolones. The method provides a diversity of N-alkyl-4-quinolones in moderate to good yields. The compound 4h demonstrated good neuroprotective activity against N-methyl-ᴅ-aspartate (NMDA)-induced excitotoxi

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2

Mollova-Sapundzhieva, Yordanka, Plamen Angelov, Danail Georgiev та Pavel Yanev. "Synthetic approach to 2-alkyl-4-quinolones and 2-alkyl-4-quinolone-3-carboxamides based on common β-keto amide precursors". Beilstein Journal of Organic Chemistry 19 (23 листопада 2023): 1804–10. http://dx.doi.org/10.3762/bjoc.19.132.

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β-Keto amides were used as convenient precursors to both 2-alkyl-4-quinolones and 2-alkyl-4-quinolone-3-carboxamides. The utility of this approach is demonstrated with the synthesis of fourteen novel and four known quinolone derivatives, including natural products of microbial origin such as HHQ and its C5-congener. Two compounds with high activity against S. aureus have been identified among the newly obtained quinolones, with MICs ≤ 3.12 and ≤ 6.25 µg/mL, respectively.

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3

Tang, Jing, and Xian Huang. "Convenient synthesis of 5-(Arylamino(Alkylthio)Methylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Diones and 2-Arylthio-4-Quinolones." Journal of Chemical Research 2003, no. 3 (2003): 140–41. http://dx.doi.org/10.3184/030823403103173264.

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Meldrum's acid reacted with an aryl isothiocynate and alkyl halides to afford the 5-(arylamino(alkylthio)methylene)-5-methylthio-2,2-dimethyl-1,3-dioxane-4,6-diones and the compounds underwent thermal cyclization to give the 4-2-arylthio-4(1 H)-quinolones

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4

Bezuglyi, P. A., I. V. Ukrainets, V. I. Treskach, and A. V. Turov. "4-Hydroxy-2-quinolones. 1. Efficient method for obtaining 3-alkyl-4-hydroxy-2-quinolones." Chemistry of Heterocyclic Compounds 27, no. 11 (1991): 1237–38. http://dx.doi.org/10.1007/bf00471752.

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5

Saalim, Muhammad, Jessica Villegas-Moreno, and Benjamin R. Clark. "Bacterial Alkyl-4-quinolones: Discovery, Structural Diversity and Biological Properties." Molecules 25, no. 23 (2020): 5689. http://dx.doi.org/10.3390/molecules25235689.

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The alkyl-4-quinolones (AQs) are a class of metabolites produced primarily by members of the Pseudomonas and Burkholderia genera, consisting of a 4-quinolone core substituted by a range of pendant groups, most commonly at the C-2 position. The history of this class of compounds dates back to the 1940s, when a range of alkylquinolones with notable antibiotic properties were first isolated from Pseudomonas aeruginosa. More recently, it was discovered that an alkylquinolone derivative, the Pseudomonas Quinolone Signal (PQS) plays a key role in bacterial communication and quorum sensing in Pseudom

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6

Vrla, Geoffrey D., Mark Esposito, Chen Zhang, Yibin Kang, Mohammad R. Seyedsayamdost, and Zemer Gitai. "Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa." PLOS Pathogens 16, no. 9 (2020): e1008867. http://dx.doi.org/10.1371/journal.ppat.1008867.

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7

BEZUGLYI, P. A., I. V. UKRAINETS, V. I. TRESKATCH, and A. V. TUROV. "ChemInform Abstract: 4-Hydroxy-2-quinolones. Part 1. Effective Preparation of 3-Alkyl-4- hydroxy-2-quinolones." ChemInform 24, no. 37 (2010): no. http://dx.doi.org/10.1002/chin.199337226.

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8

Chen, Bang-chi, Xian Huang, and Jin Wang. "A Versatile Synthesis of 2-Alkyl and 2-Aryl 4-Quinolones." Synthesis 1987, no. 05 (1987): 482–83. http://dx.doi.org/10.1055/s-1987-33427.

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9

Gupta, Rashmi, and Martin Schuster. "Quorum sensing modulates colony morphology through alkyl quinolones in Pseudomonas aeruginosa." BMC Microbiology 12, no. 1 (2012): 30. http://dx.doi.org/10.1186/1471-2180-12-30.

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10

Michalet, S., P. M. Allard, C. Commun, et al. "ePS6.03 Alkyl-Quinolones derivatives could predict Pseudomonas infection chronicity in cystic fibrosis." Journal of Cystic Fibrosis 19 (June 2020): S52—S53. http://dx.doi.org/10.1016/s1569-1993(20)30331-3.

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