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Relevant bibliographies by topics / Alloxan-induced diabetic

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Academic literature on the topic 'Alloxan-induced diabetic'

Author: Grafiati

Published: 7 June 2025

Last updated: 17 July 2025

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Journal articles on the topic "Alloxan-induced diabetic"

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Sultana, S., N. Y. Mili, R. Afroz, and S. Parveen. "Preventive Role of Zingiber Officinale against Hyperglycemia in Alloxan Induced Diabetic Rats." Journal of Medical Science & Research 30, Number 1 (2019): 26–29. http://dx.doi.org/10.47648/jmsr.2019.v3001.05.

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The experimental animal study was undertaken to investigate the preventive role ginger juice against hyperglycemia in alloxan induced diabetic rats.Male wistar rats,(130-150)gm wt fed on standard diet and water ad libitum, were divided into 3 groups(n=6) in each group: Group-L non-diabetic control group, Group-II, diabetic control & Group-III, normal rats pretreated with ginger before they were made diabetics. Diabetes was induced by inj. alloxan 150mg/kg body wt.,tp (Group-IL on 2nd day & Group-Ill, on the 9th day).Rats having blood glucose level of more than 7mmol/L on day 5(72 hours

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Farheen, Mehnoor, and Chakrapani Ramesh. "Phytochemical evaluation and pharmacological screening of ethanolic and aqueous leaf extracts of Pupalia lappacea for antihyperlipidemic and antihyperglycemic activities in alloxan induced diabetic Albino wistar rats." International Journal of Basic & Clinical Pharmacology 7, no. 4 (2018): 753. http://dx.doi.org/10.18203/2319-2003.ijbcp20181182.

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Background: Diabetes is associated with damage to the liver, pancreas and kidney. The damage may vary among patients. This study assessed the hypoglycaemic and antihyperlipidemic activities of leaves ethanolic and aqueous extracts of Pupalia lappaceae in alloxan induced diabetic albino wistar rats.Methods: There were Fifty four rats divided into nine groups containing six rats each. Group 1 consists of normal rats that were given only normal saline and served as a control group. Group 2 consists of normal rats that were given alloxan monohydrate (150mg/kg b.w). Group 3 consists alloxan induced

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Ahamefula Sunday Ezekwe, Karibo Amakiri Okari, Peter Gift Wokocha, Mike Tochi Achor, and Boma Ngo Fubara. "Evaluating alloxan-induced diabetic rats." International Journal of Science and Research Archive 13, no. 2 (2024): 3544–52. https://doi.org/10.30574/ijsra.2024.13.2.2499.

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The increasing incidence of diabetes and the adverse effects of chemical medications underscore the importance of exploring alternative non-pharmacological treatments. Vernonia amygdalina, a widely utilized medicinal herb, shows promising therapeutic potential. This study investigated the impact of aqueous leaf extracts of Vernonia amygdalina on various biochemical parameters in alloxan-induced diabetic rats. Diabetes was induced in male Wistar rats through intraperitoneal injection of alloxan (150 mg/kg). The rats were then randomly divided into four groups: Group 1 (normal control), Group 2

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Sultana, Selima, Shakil Akter, and Md Ismail Khan. "Anti-Hyperlipidemic Action of Zingiber officinale (Ginger) Juice in Alloxan Induced Diabetic Rats." Ibrahim Medical College Journal 6, no. 2 (2013): 55–58. http://dx.doi.org/10.3329/imcj.v6i2.14730.

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Hyperlipidemia is an important modifiable risk factor contributing to atterosclerosis in diabetes mellitus. Zingiber officinale (ginger) widely consumed as spice is known for its hypoglycemic and hypochlosteremic actions. The present study was undertaken to investigate anti-hyperlipidemic action of ginger juice in alloxan-induced diabetic rats. Male Wister rats, 130-150 g wt, fed on standard diet and water ad libitum were divided into 4 groups (n=6 in each group): group I nondiabetic control, group II non-diabetic treated; group III diabetic control and group IV diabetic treated. Diabetes was

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Simorangkir, Murniaty, Erlintan Sinaga, and Saronom Silaban. "HEPATOPROTECTIVE AND HISTOLOGICAL PANCREAS EFFECTS OF Sarang Banua (Clerodenrum fragrans Vent Willd) LEAF EXTRACT IN ALLOXAN-INDUCED DIABETIC RATS." RASAYAN Journal of Chemistry 15, no. 03 (2022): 1846–54. http://dx.doi.org/10.31788/rjc.2022.1536979.

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Research on anti-diabetic herbal plants and their safety continues to grow by the increasing number of diabetics, especially in Indonesia, which is rich in plant biodiversity. This study investigated the effect of Sarang banua (Clerodendrum fragrans Vent Willd) leaf extract on the hepatoprotective effect, histology of the pancreas, and serum glucose levels of white male rats (Rattus novergicus) induced diabetes by alloxan. Diabetic rats were given ethanol extract of C. fragrans leaf (100, 200, and 300 mg/kg bw), ethyl acetate extract (200, 300 mg/kg bw), and metformin (125 mg/kg) orally for 14

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Ekinci, Bilge, Bahadir Suleyman, Renad Mammadov, et al. "The effect of carvacrol upon experımentally ınduced dıabetıc neuropathy and neuropathıc paın ın rats." Acta Poloniae Pharmaceutica - Drug Research 79, no. 5 (2023): 707–15. http://dx.doi.org/10.32383/appdr/155354.

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Diabetic neuropathies are the most frequent complication of diabetes. While numerous metabolic pathways are disrupted in diabetic neuropathy, oxidative stress has been indicated as a significant reason for this condition. In this study, the effect of carvacrol, which has antioxidant effects, on experimental diabetic neuropathy and neuropathic pain was investigated. Alloxan was used to induce diabetes in the experiment. Diabetes was created by administering 120mg/kg of alloxan intraperitoneally (i.p) once a day for 3 days. Rats with a blood glucose concentration above 250mg/kg in the blood take

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Stalin, Chandrasekeran, V. Gunasekaran, and G. Jayabalan. "Evaluation of Neuroprotective Effect of Ficus benghalensis against Alloxan Induced Diabetic Neuropathy in Rats." International Journal of Pharmacology, Phytochemistry and Ethnomedicine 4 (August 2016): 52–60. http://dx.doi.org/10.18052/www.scipress.com/ijppe.4.52.

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Neuropathic pain in diabetics is characterized by both hyperalgesia and allodynia. This is attributed to both uncontrolled glycemia and the further complications which it leads to. The objective of the study was to evaluate the neuroprotective effect of methanolic leaf extract of Ficus benghalensis against alloxan induced diabetic neuropathy in rats.Material and methods:Experimental diabetes was induced in wistar albino rats by single intraperitoneal injection of Alloxan monohydrate (150 mg/kg). The methanolic extract of leaves of Ficus benghalensis at a dose of 200 and 400 mg/kg body weight w

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Kingsley Chimsorom Chilaka, Amarachi Chioma Opara, Ugochinyere Jane Chilaka, Godwin Christian Akuodor, Mansur Aliyu Ramalan, and Ekene Enekabokom Nwoke. "Comparative effects of combinations of metformin, omega-3 and omega-6 oil in the treatment of alloxan-induced diabetic rats." Magna Scientia Advanced Biology and Pharmacy 6, no. 1 (2022): 016–32. http://dx.doi.org/10.30574/msabp.2022.6.1.0066.

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Emerging evidence suggests beneficial effects of omega fatty acids on diabetic complications. This study was designed to investigate the impact of Omega-3 and Omega-6 oil in the management of oxidative stress associated with complications in diabetes in alloxan induced diabetic rats. Experimental rats used in this study were grouped into four as non-diabetics and untreated, alloxan induced diabetic group, alloxan induced and treated with Metformin, lloxan induced and administered Metformin + Omega-3, alloxan induced and administered Metformin + Omega-6 oil. Effect of Metformin + Omega-3 and Me

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Aslam, Huma, Arif-ullah Khan, Najeeb-ur Rehman, Fawad Ali, Humaira Nadeem, and Syed Majid Shah. "Anti-hyperglycemic activity of Heliotropium strigosum (Boraginaecae) whole plant extract in alloxan-induced diabetic mice." Tropical Journal of Pharmaceutical Research 16, no. 10 (2017): 2425–30. http://dx.doi.org/10.4314/tjpr.v16i10.16.

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Purpose: To investigate Heliotropium strigosum whole plant extract for its potential to reduce the blood glucose level of alloxan-induced diabetic mice.Methods: Preliminary phytochemical analysis was carried out using standard procedures. Diabetes was induced in Balb/c mice by injecting alloxan (200 mg/kg i.p.). The crude methanol extract of Heliotropium strigosum (Hs.Cr, 30, 100 and 300 mg/kg doses) was administered daily to alloxan-induced diabetic mice for 15 days and its effect on fasting blood glucose levels, body weight and oral glucose tolerancewas evaluated. Two control groups (non-dia

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Hussaini, SMAK, MI Hossain, MS Islam, and K. Rafiq. "Effects of Spirulina platensis on alloxan induced diabetic rats." Progressive Agriculture 29, no. 2 (2018): 139–46. http://dx.doi.org/10.3329/pa.v29i2.38300.

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The study was undertaken to investigate the effects of Spirulina platensis on body weight, blood glucose and lipid profile on alloxan induced diabetic rats. Fifteen Long Evans male rats at six weeks of age were used for the experiment. Diabetes was induced by intraperitoneal injection of alloxan@ 150 mg/kg and experiment was carried out for a period of 6 weeks. Rats were divided into three groups of 5 rats each. The groups were i)healthy control, ii) diabetic control with both receiving rats’ pellet as supplement, and iii) diabetic treated with oral administration of Spirulina platensis @ 400

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Dissertations / Theses on the topic "Alloxan-induced diabetic"

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Olenovych, O. A. "Tubulointerstitial syndrome in the early period of alloxan-induced experimental diabetes." Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18834.

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Iles, Karen Elizabeth. "The role of CuZnSOD activity in the susceptibility to alloxan-induced diabetes in mice." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0005/NQ43261.pdf.

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Olenovych, O. A. "Peculiarities of acid-regulating renal function disorders in the early period of alloxan-induced experimental diabetes." Thesis, БДМУ, 2020. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18337.

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Davydova, N. V. "The influence of melatonin on glutathione-S-transferase activity in the kidneys of rats under alloxan-induced diabetes." Thesis, БДМУ, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/16860.

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Graham, Kristi L. "The effects of furosemide administration on glucose homeostasis in healthy dogs and dogs with alloxan-induced insulinopenic diabetes mellitus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0001/MQ43502.pdf.

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Dool, Carly Jade 1985. "Pharmacologic inhibition of insulin receptor tyrosine kinase activity has antineoplastic effects similar to alloxan-induced insulin deficiency with less acute metabolic toxicity." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111555.

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Recent population studies provide evidence that individuals with high circulating insulin levels have a poor prognosis and/or increased risk of cancer development; however, laboratory studies concerning the role of insulin in breast cancer biology are sparse. We compared the growth of 4T1 murine breast cancer allografts in control mice, alloxan-induced hypoinsulinemic mice, and mice treated with the insulin/insulin-like growth factor-1 receptor tyrosine kinase inhibitor BMS-536924. Both interventions significantly decreased tumor growth versus control and decreased pathway activation downstrea

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Novak, D. I., and O. A. Olenovych. "Fibrinolytic activity of urine in case of experimental diabetes mellitus." Thesis, XV International Congress of Medical Sciences «Starway to science – Imagine, Invent, Inspire!». – Abstract Book (тези). –Sofia, Bulgaria, 12-15 May, 2016. – P.121, 2016. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/11535.

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"Responses to vascular injury in the alloxan-induced diabetic rabbit." Tulane University, 1999.

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The cascade of pathophysiological events that ensue in response to vascular injury is analogous to generalized wound healing. Vascular injury in which the endothelial cell layer is denuded and the underlying vascular smooth muscle cell (VSMC) layer is disrupted results in an expansion of the neointima. The phases of the healing process are controlled in large part by growth factors released at the site of injury Once cells are made competent, progression factors such as insulin-like growth factor-1 (IGF-1) act to promote cells through the cell cycle and thus, allow for a full proliferative res

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pei-hui, Wang, and 王珮憓. "The Study of Hypoglycemic Effects of Toona Sinensis Aqueous Leaf Extracts on Alloxan-induced Diabetic Rats." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/86408924252570713206.

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碩士<br>高雄醫學大學<br>醫學研究所<br>89<br>Toona sinensis (TS) is a broadleaf tree, which grows all around the world, which is composed of only four or five ‘good’ species. TS are the only Toona species in which the leaflet margins can be serrate to serrulate. The trees provide very high quality timber and are widely used medicinally, the bark being used as an astringent and depurative, the root as a refreshment and a diuretic, the tender leaves as a carminative and a corrective, and the fruits as an astringent and for treatment of eye infections. The leaves and young shoots have been used as a vegetable

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Bi, Yi Jia. "Alterations in cardiac responses to adrenergic agonists and in circulating thyroid hormones in alloxan induced diabetic rats." Thesis, 1994. http://hdl.handle.net/2429/5119.

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The effects of adrenergic agonists in the heart were investigated in isolated cardiac tissues and in the whole heart in 8 week diabetic and age-matched control rats by measuring contractile force following administration of PE in presence of timolol, or ISO. Plasma thyroid hormones as well as insulin, glucose and triglyceride was measured. The contractile force of the isolated cardiac tissues was measured in tissue baths under physiological conditions and results expressed by construction of concentration response curves to adrenoceptors agonists, 10⁻⁹ to 10⁻⁴ M for ISO and 10⁻⁷ to 10⁻³

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Book chapters on the topic "Alloxan-induced diabetic"

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Shanmuganathan, T., and A. V. P. Karthikeyan. "Evaluation of Anti-diabetic Activity of Cleome gynandra in Alloxan Induced Diabetic Wistar Albino Rats." In Phytomedicine. CRC Press, 2020. http://dx.doi.org/10.1201/9781003014898-18.

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Renuka, C., K. Saravanan, and P. Karuppannan. "Hypoglycemic Activity of Biophytum sensitivum Whole Plant Extracts on Alloxan Induced Diabetic Rats." In Drug Development for Cancer and Diabetes. Apple Academic Press, 2020. http://dx.doi.org/10.1201/9780429330490-23.

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Misawa, T., Y. Kutsumi, H. Tada, et al. "In Vivo 31-NMR Spectroscopic Investigation of Myocardial Energy Metabolism in Alloxan-Induced Diabetic Rabbits." In Developments in Cardiovascular Medicine. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3512-6_22.

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Witek, Bożena, Danuta Rochon-Szmejchel, Iwona Stanisławska, et al. "Activities of Lysosomal Enzymes in Alloxan-Induced Diabetes in the Mouse." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/5584_2017_102.

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Golfman, Leonard, Ian M. C. Dixon, Nobuakira Takeda, Anton Lukas, Krishnamurti Dakshinamurti, and Naranjan S. Dhalla. "Cardiac sarcolemmal Na+-Ca2+ exchange and Na+-K+ ATPase activities and gene expression in alloxan-induced diabetes in rats." In Molecular and Cellular Effects of Nutrition on Disease Processes. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5763-0_11.

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Sultana, Fatima, Rama Rao, and Anupama K. "Screening of Antidiabetic Activity of Crude Extract of Celastrus Paniculatus in Alloxan Induced Diabetic Rat Model." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00685.

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Diabetes mellitus is the commonest form of endocrine disorder that is characteristic of hyperglycaemia. This is due to a defective metabolic system of fat, proteins, and carbohydrates leading to major health challenges. Around 800 medicinal plants have hypoglycaemic properties worldwide. Diabetic complications can be slowed and metabolic abnormalities can be restored by the use of plant products. The antidiabetic property of Celastrus paniculatus seed extract (CPSE) is studied. The seeds containing phytochemicals - alkaloids, sterols, triterpenoids, flavonoids, saponins, and tannins were evaluated using standard procedures. Single day hypoglycaemic study was done by taking 800 and 1600 mg kg-1 body-weight and blood samples were collected at 0, 30, 60, 120 min. to evaluate blood glucose levels using glucometer. Oral glucose tolerance study was conducted on normal rats by giving 50% glucose solution of 2 g kg-1 body-weight by p.o. route, half an hour after sample and standard drug administration, blood samples were collected 30 min after glucose was given and continued at 60 min, 90 min, and 120 min. Alloxan-induced diabetic study was done by taking 400 mg kg-1 and 800 mg kg-1 doses of CPSE and recording blood glucose levels on 0, 4, 7 14 and 21 days of study. In the histopathological studies of pancreas, the disease control group showed a high degree of hypertrophy and hyperplasia of pancreatic cells. Samples from CPSE 800 mg kg-1 treated group showed no apoptosis or necrosis and normal acinar cells. The results suggest that CPSE may possess antidiabetic action.

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Olusanya, Arise Rotimi, Bankole S. Ifeoluwa, Aboyewa Jumoke A., and Bobbo Khadijat. "Antidiabetic and Safety Properties of Ethanolic Leaf Extract of Corchorus olitorius in Alloxan-Induced Diabetic Rats." In Diabetes Food Plan. InTech, 2018. http://dx.doi.org/10.5772/intechopen.71529.

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Nwankwo, Michael O., Innocent O. Ogbonna, and Etim, Esin Etim. "Determination of the Anti-diabetic Activity of Sphenostylis stenocarpa Seed Milk Extract in Alloxan-induced Diabetes Rats." In Recent Developments in Medicine and Medical Research Vol. 16. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/rdmmr/v16/5210f.

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Karan, Sanjay Kumar, Dilipkumar Pal, Sagar Kumar Mishra, and Arijit Mondal. "Investigating the Antihyperglycaemic Effect of Vetiveria zizanioides (L.) Nash Root Extract in Alloxan-induced Diabetic Rats." In Advanced Concepts in Pharmaceutical Research Vol. 9. B P International, 2024. http://dx.doi.org/10.9734/bpi/acpr/v9/3638g.

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Kasolo, Josephine N., Agnes Namaganda, Joshua Nfambi, et al. "Hyperglycemic Control of Moringa oleifera Leaves Aqueous Extract and Glibenclamide Tablets in Alloxan Monohydrate Induced Diabetic Rats: A Comparative Analysis." In Current Overview on Pharmaceutical Science Vol. 9. B P International (a part of SCIENCEDOMAIN International), 2023. http://dx.doi.org/10.9734/bpi/cops/v9/17898d.

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Conference papers on the topic "Alloxan-induced diabetic"

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Wu, Ming, and Li-Quan Guo. "Hypoglycemic Effects of Polysaccharides from Radix Astragali in Alloxan-Induced Diabetic Mice." In 2015 International Conference on Energy, Environmental & Sustainable Ecosystem Development (EESED 2015). WORLD SCIENTIFIC, 2015. http://dx.doi.org/10.1142/9789814723008_0157.

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"Antidiabetic effect of Ziziphus Jujuba fruit in Alloxan induced diabetic male rats." In International Conference on Medicine, Public Health and Biological Sciences. CASRP Publishing Company, Ltd. Uk, 2016. http://dx.doi.org/10.18869/mphbs.2016.61.

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Hidayati, Dewi, Nurlita Abdulgani, Hengki Setiyawan, Indah Trisnawati, Nova Maulidina Ashuri, and Noor Nailis Sa’adah. "Analysis of protein profiles in diabetic rat blood plasma that induced by alloxan." In PROCEEDING OF INTERNATIONAL BIOLOGY CONFERENCE 2016: Biodiversity and Biotechnology for Human Welfare. Author(s), 2017. http://dx.doi.org/10.1063/1.4985407.

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"Antidiabetic effect of Rosa canina L. fruit in alloxan induced diabetic male rats." In International Conference on Medicine, Public Health and Biological Sciences. CASRP Publishing Company, Ltd. Uk, 2016. http://dx.doi.org/10.18869/mphbs.2016.230.

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Inke, Lola Anandya, Subeki, Sri Hidayati, Tanto Pratondo Utomo, and Sussi Astuti. "The effect of waxy siger rice on lipid profile diabetic mice induced by alloxan." In THE 3RD INTERNATIONAL CONFERENCE ON PROGRESSIVE EDUCATION (ICOPE) 2021: Harmonizing Competencies in Education Transformation towards Society 5.0. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0142379.

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Wu, Ming, and Liquan Guo. "Protective Effects of Polysaccharides from Radix Astragali Against Alloxan-induced Oxidative Stress in Diabetic Mice." In 2016 2nd International Conference on Advances in Energy, Environment and Chemical Engineering (AEECE 2016). Atlantis Press, 2016. http://dx.doi.org/10.2991/aeece-16.2016.30.

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Stolbovskaya, Olga, Boris Kostishko, Radik Khayrullin, and Rinat Bakhtiyarov. "Structural features of blood lymphocytes according to data of atomic force microscopy in alloxan induced diabetic rats." In Saratov Fall Meeting 2017: Fifth International Symposium on Optics and Biophotonics: Optical Technologies in Biophysics & Medicine XIX, edited by Valery V. Tuchin, Dmitry E. Postnov, Elina A. Genina, and Vladimir L. Derbov. SPIE, 2018. http://dx.doi.org/10.1117/12.2315077.

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Surya, Henny, Maruli Pandjaitan, and Abdullah Muzi Marpaung. "The effect of spray dried butterfly pea (Clitoria ternatea L.) leaf extract on alloxan-induced diabetic mice." In 2013 3rd International Conference on Instrumentation, Communications, Information Technology, and Biomedical Engineering (ICICI-BME). IEEE, 2013. http://dx.doi.org/10.1109/icici-bme.2013.6698518.

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Wu, Hongmei, Feng Xu, Junjie Hao, Ye Yang, and Xiangpei Wang. "Antihyperglycemic Activity of Banana (Musa nana Lour.) Peel and Its Active Ingredients in Alloxan-Induced Diabetic Mice." In 3rd International Conference on Material, Mechanical and Manufacturing Engineering (IC3ME 2015). Atlantis Press, 2015. http://dx.doi.org/10.2991/ic3me-15.2015.44.

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Eden, Willy Tirza, Nor Solekah, Izzatun Nufus, Marliana Eka Puji Lestari, and Poppy Diah Palupi. "The effect of nanoencapsulation effervescent powder of jengkol peel (Pithecellobium jiringa) in the alloxan-induced diabetic mice." In INTERNATIONAL CONFERENCE ON APPLIED COMPUTATIONAL INTELLIGENCE AND ANALYTICS (ACIA-2022). AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0128015.

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Reports on the topic "Alloxan-induced diabetic"

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Yibchok-anun, Sirintorn, and Wara Panichkriangkrai. The role of arginine vasopressin in diabetes-associated glucagons secretion. Chulalongkorn University, 2002. https://doi.org/10.58837/chula.res.2002.63.

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The purpose of this study was to investigate the role of arginine-vasopressin (AVP) on glucagons secretion in both normal and diabetic rats. Diabetes was induced by intraperitoneal administration of alloxan HCI(200 mg/kg). Both glucagon and AVP were determined in the effluent of the perfused pancreas using radioimmunoassay. Diabetic rats had higher baseline glucagons concentrations than normal rats. AVP (1 pmol/L) failed to change glucagons secretion in normal rats, but significantly increased glucagons secretion in diabetic rats. AVP (10-100 pmol/L) increased glucagons secretion from both nor

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