Academic literature on the topic 'Alloxane diabetes'

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Journal articles on the topic "Alloxane diabetes"

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Luhinich, N. M., I. V. Gerush, and N. P. Grygorieva. "EFFECTS OF MELATONIN ON OXIDANT AND ANTIOXIDANT STATUSIN THE BLOOD OF ALLOXAN DIABETIC RATS." Medical and Clinical Chemistry, no. 4 (January 31, 2019): 5–10. http://dx.doi.org/10.11603/mcch.2410-681x.2018.v0.i4.9781.

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Introduction. The experimental model of alloxane diabetes is quite common, which is often used to study the different aspects of pathogenesis and pathomorphology of diabetes. It is known that during the diabetes activation of free radical oxidation of biomolecules occurs as well as depletion of the antioxidant system. Melatonin can suppress reactive oxygen species and increases the activity of antioxidant enzymes.
 The aim of the study – to investigate the effect of melatonin on oxidant and antioxidant status in the blood of alloxan diabetic rats.
 Research Methods. Experiments were
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Firdausi, Khadijah Nur Al, Sugiyanta Sugiyanta, and Pipiet Wulandari. "Comparative Effectiveness of Corn Oil (Zea mays) with Pure Coconut Oil (Cocos nucifera L.) to Reduced Glucose Blood Levels of Alloxane Injected Wistar Rats." Journal of Agromedicine and Medical Sciences 3, no. 3 (2017): 50. http://dx.doi.org/10.19184/ams.v3i3.6193.

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Epidemiological studies show an increased incidence of diabetes mellitus. The initial therapy of diabetes mellitus is a diet treatment. The recommended intake of fat is a Saturated Fatty Acids (SFA) <7% and a Polyunsatturated Fatty Acid (PUFA) <10% of calories. The corn oil contains PUFA and the virgin coconut oil contains SFA as the main component. Aims of this study was to compare the effectivity of corn oil (Zea mays) and virgin coconut oil (Cocos nucifera L.) in decreasing blood glucose level in alloxane-ijnected wistar rats. This was a laboratory experiment research, used the postte
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Fayzieva, Ziyoda, and Ziyovutdin Khakimov. "Influence of glycorazmulin on the parameters of carbohydrate metabolism in alloxane diabetes." Medical and Health Science Journal 3, no. 3 (2010): 5–8. http://dx.doi.org/10.15208/mhsj.2010.36.

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Ponyrko, A. A., T. P. Teslyk, and N. S. Pernakov. "Biological Modeling of Type I Diabetes Mellitus with Alloxane with Modified Chemical Properties." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 2, no. 6 (2017): 30–33. http://dx.doi.org/10.26693/jmbs02.06.030.

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Shestakova, S. A., M. L. Stepanyan, V. A. Titova, and N. V. Boikova. "Functional activity of platelets in the early periods of angiopathy formation in rats with alloxane diabetes." Problems of Endocrinology 42, no. 4 (1996): 34–37. http://dx.doi.org/10.14341/probl12074.

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Functional and metabolic activity of platelets and anti-aggregation activity of aortic wall, as well as the specific features in the structure of renal glomeruli were studied in rats at the early stages of alloxan diabetes development. A decrease of platelet disaggregation, an increase in the levels of malonic dialdehyde (MDA) in nonactivated platelets, and an expressed increase of MDA production by thrombin-activated platelets were observed in animals with 15-day diabetes mellitus. A depression of the anti-aggregation activity of the aorta was observed in the same period. In the renal glomeru
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Gümüşlü, Saadet, Piraye Yargiçoğlu, Aysel Ağar, Mustafa Edremitlioğlu, and Yakup Alicigüzel. "Effect of cadmium on antioxidant status in alloxane-induced diabetic rats." Biological Trace Element Research 57, no. 2 (1997): 105–14. http://dx.doi.org/10.1007/bf02778193.

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Derouiche, Samir, Manel Azzi, and Abir Hamida. "EFFECT OF EXTRACTS AQUEOUS OF PHRAGMITES AUSTRALIS ON CARBOHYDRATE METABOLISM, SOME ENZYME ACTIVITIES AND PANCREATIC ISLET TISSUE IN ALLOXAN-INDUCED DIABETIC RATS." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 6 (2017): 54. http://dx.doi.org/10.22159/ijpps.2017v9i6.17321.

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Objective: The present study was aimed to investigate the effects of the aqueous extract of rhizome of phragmites australis on carbohydrate metabolism, some enzyme activities and pancreatic tissue in alloxan induced diabetic rats.Methods: Wistar rats were divided into three groups (n=6) as control, diabetic group and test groups (Diabetic+AEPA). Diabetes in rats was induced by alloxane using a single peritoneal injection of 150 mg/kg dose. Aqueous extract of Phragmites australis was supplemented (200 mg/kg b. w) orally for three weeks. The aqueous extract of Phragmites australis was prepared a
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Canda, Abdullah, Safiye Aktas, Burak Turna, and Mehtap Cinar. "Does diabetes affect the intensity of staining of interstitial cells and neuronal tissue in the bladder, prostate and urethra of rabbits?" Open Medicine 5, no. 1 (2010): 108–14. http://dx.doi.org/10.2478/s11536-009-0064-z.

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AbstractWe compared the intensity of staining of interstitial cells (ICs) and neural tissue in the lower urinary tract of rabbits with diabetes with the intensity in normal subjects. Diabetes was induced by injecting alloxane (65mg/kg) in adult male rabbits. After 3 days, rabbits with a blood glucose level >300 mg/dL were considered to have diabetes. After 8 weeks, the rabbits were killed, and tissue specimens from the bladder, prostate and urethra were obtained. ICs were stained with anti-human CD117 (c-kit) rabbit polyclonal antibody, and neural tissue was stained with synaptophysin. The
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Osadchuk, Yu S., Yu B. Chaykovskii, L. V. Natrus, and T. S. Bryuzgina. "FEATURES OF CHANGES IN FATTY ACIDS COMPOSITION OF TISSUES IN DIFFERENT MODELS OF EXPERIMENTAL TYPE 1 DIABETES." Medical Science of Ukraine (MSU) 14, no. 3-4 (2018): 13–22. http://dx.doi.org/10.32345/2664-4738.3-4.2018.02.

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Relevance. Alloxan and streptozotocin are used for experimental modeling of hyperglycemia. Damaged β-cells with these compounds lead to the reduction of synthesis and secretion of the level of insulin in the blood, as a result of which animals develop hyperglycemia and diabetic syndrome, similar to insulin-dependent type 1 diabetes. One of the methodological approaches for assessing the degree and development of tissue damage of vital organs, including diabetes, is the study of their fatty acid composition. But for the planning of an experiment with type 1 diabetes, it is necessary to take int
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Yargiçoğlu, P., A. Ağar, M. Edremitlioğlu, Y. Oğuz, and C. Apaydin. "The effect of cadmium on visual evoked potentials in alloxane-induced diabetic rats: relation to lipid peroxidation." Acta Diabetologica 36, no. 4 (1999): 197–204. http://dx.doi.org/10.1007/s005920050167.

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Dissertations / Theses on the topic "Alloxane diabetes"

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Vinichenko, I. "Morphological changes in pancreas after induce diabetes in young rats." Thesis, Sumy State University, 2017. http://essuir.sumdu.edu.ua/handle/123456789/65516.

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Diabetes mellitus is chronic endocrine metabolic disease which is caused by the action of endogenous factors, with relative or absolute insufficiency of insulin, leading to disorders of metabolism. Diabetes mellitus induce by using alloxan which related to hyperglycemias' chemicals due to increase hepatic glucose.
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Теслик, Тетяна Петрівна, Татьяна Петровна Теслик та Tetiana Petrivna Teslyk. "Особливості змін лімфоїдної тканини легень білих щурів за умов експериментального алоксанового діабету". Thesis, Чорноморський національний університет ім. Петра Могили, 2017. http://essuir.sumdu.edu.ua/handle/123456789/65374.

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Реакцією на хронічну гіперглікемію з боку лімфоїдної тканини легень щурів є її гіперплазія, але спостерігається наступна тенденція – у щурів старечого та зрілого віку активна гіперплазія починається з 150 доби експерименту, у щурів молодого віку – збільшення лімфатичних вузлів відбувається поступово.<br>Реакцией на хроническую гипергликемию со стороны лимфоидной ткани легких крыс является ее гиперплазия, но наблюдается следующая тенденция – у крыс старческого и зрелого возраста активная гиперплазия начинается со 150 дня эксперимента, у крыс молодого возраста – увеличение лимфатических узлов пр
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Бумейстер, Валентина Іванівна, Валентина Ивановна Бумейстер, Valentyna Ivanivna Bumeister та І. С. Діденко. "Гістологічна структура регіонарних лімфатичних вузлів підшлункової залози при алоксановій гіперглікемії". Thesis, Сумський державний університет, 2017. http://essuir.sumdu.edu.ua/handle/123456789/65538.

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Вступ. Функціонування підшлункової залози визначається станом як екзо– та ендокринної частини, так і станом крово– та лімфотоку, від яких залежить баланс рівень окисно–відновних процесів, робота ферментативних систем. Лімфатичні вузли (ЛВ) досить чутливі до дії різних екзо– та ендогенних факторів. Літературні дані про топографію ЛВ досить обмежені та досить суперечливі. Гістологічна структура ЛВ підшлункової залози щурів досліджена недостатньо.
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Kushnir, О. Yu. "Glucose tolerance profiles in rats with alloxan diabetes." Thesis, БДМУ, 2020. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18366.

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Olenovych, O. A. "Tubulointerstitial syndrome in the early period of alloxan-induced experimental diabetes." Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18834.

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Schulte, im Walde Sabine. "Molekulare Zielstrukturen im Alloxan-induzierten Diabetesmodell der Maus." Doctoral thesis, Universitätsbibliothek Leipzig, 2004. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-33556.

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Alloxan (ALX) ist ein klassisches Diabetogen, welches in Nagetieren spezifisch pankreatische ß-Zellen zerstört und Symptome induziert, die dem humanen Typ-1-Diabetes vergleichbar sind. Durch eine einmalige, intravenöse (iv) Injektion einer subtoxischen Dosis von 50 mg ALX/kg Körpergewicht (KG) werden Schäden an der ß-Zelle hervorgerufen, die innerhalb von 48-72 Stunden in &#61603;50% der Mäuse einen Diabetes auslösen (Schwellenwert Euglykämie zu Hyperglykämie ist 11,1 mmol/l). Das toxische Potential von ALX besteht in der Generierung von reaktiven Sauerstoffspezies (ROS), vorwiegend Superoxida
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Tessaro, Fernando Henrique Galvão. "Ação da insulina na liberação de citocinas por macrófagos residentes de camundongos diabéticos estimulados com lipopolissacarídeo." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-06052015-112126/.

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Indivíduos diabéticos apresentam incidência elevada de doenças infecciosas. Isto pode estar relacionado às alterações na capacidade da resposta destes indivíduos aos agentes agressores. Em animais diabéticos, algumas destas alterações já foram descritas, assim como sua reversão pela administração de insulina. Este hormônio regula o metabolismo celular, modulando a atividade de proteínas e mediadores inflamatórios envolvidos neste processo. Sabemos que o lipopolissacarídeo (LPS) estimula, em macrófagos alveolares (MA) de animais não-diabéticos, a liberação do fator de necrose tumoral (TNF)-&#94
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Silva, Marcela Claudino da. "Análise histológica e radiográfica das alterações periodontais provocadas pela indução do diabetes em ratos." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/25/25142/tde-20062007-101447/.

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Pacientes diabéticos apresentam maior severidade e prevalência de doenças periodontais. Em ratos diabéticos, a doença periodontal induzida com ligaduras e inoculação de bactérias é mais severa. Contudo, na ausência de estímulos agressivos como ligaduras, a influência do diabetes sobre o periodonto de rato é pouco conhecida. O objetivo deste estudo foi avaliar a presença e a progressão da doença periodontal por longos períodos apenas com a indução do diabetes. O diabetes foi induzido em ratos Wistar (n=25) pela administração endovenosa de 42mg/kg de aloxana e, juntamente com os animais controle
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Iles, Karen Elizabeth. "The role of CuZnSOD activity in the susceptibility to alloxan-induced diabetes in mice." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0005/NQ43261.pdf.

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Харченко, Аліна Олександрівна, Ірина Миколаївна Яремій, and Олександра Юріївна Кушнір. "Effect of melatonin prolonged infusion on the functioning of glutathione system in the blood of alloxan diabetic rats in lighting conditions around the clock." Thesis, 39th International Medical Scientific Congress, 2016. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/11211.

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Under conditions of permanent light exogenous melatonin activates antioxidant glutathione dependent enzymes in the blood of alloxan diabetic rats that ultimately provides increased content of G-SH - one of the main endogenous antioxidant.<br>Кафедра біоорганічної і біологічної хімії та клінічної біохімії
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Books on the topic "Alloxane diabetes"

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Wasserman, David H. Determinants of glucose fluxes during exercise in normal and alloxin-diabetic dogs. 1985.

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Glycogen synthase in canine skeletal muscle: Effects of acute and chronic exercise in normals and diabetics. 1988.

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Glycogen synthase in canine skeletal muscle: Effects of acute and chronic exercise in normals and diabetics. 1988.

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Glycogen synthase in canine skeletal muscle: Effects of acute and chronic exercise in normals and diabetics. 1985.

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Glycogen synthase in canine skeletal muscle: Effects of acute and chronic exercise in normals and diabetics. 1988.

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Book chapters on the topic "Alloxane diabetes"

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Bielschowsky, F., and Marianne Bielschowsky. "Carcinogenesis in Alloxan-Diabetic Rats." In Ciba Foundation Symposium - Carcinogenesis: Mechanisms of Action. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470719138.ch9.

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Lenzen, Sigurd, Markus Tiedge, Anne Jörns, and Rex Munday. "Alloxan derivatives as a tool for the elucidation of the mechanism of the diabetogenic action of alloxan." In Lessons from Animal Diabetes VI. Birkhäuser Boston, 1996. http://dx.doi.org/10.1007/978-1-4612-4112-6_8.

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Chung, Y. M. I., P. M. M. Chiu, and H. L. Wong. "Modification of Alloxan Diabetes in Rats by Vitamin a Status." In Lipid-Soluble Antioxidants: Biochemistry and Clinical Applications. Birkhäuser Basel, 1992. http://dx.doi.org/10.1007/978-3-0348-7432-8_22.

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Renuka, C., K. Saravanan, and P. Karuppannan. "Hypoglycemic Activity of Biophytum sensitivum Whole Plant Extracts on Alloxan Induced Diabetic Rats." In Drug Development for Cancer and Diabetes. Apple Academic Press, 2020. http://dx.doi.org/10.1201/9780429330490-23.

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Roth, David M., Diane K. Reibel, and Allan M. Lefer. "Lipid Analysis of Aortic Tissue from Alloxan-Diabetic Rats." In Developments in Cardiovascular Medicine. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4613-2589-5_35.

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Witek, Bożena, Danuta Rochon-Szmejchel, Iwona Stanisławska, et al. "Activities of Lysosomal Enzymes in Alloxan-Induced Diabetes in the Mouse." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/5584_2017_102.

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Allegri, Graziella, Delia Zaccarin, Eugenio Ragazzi, Guglielmina Froldi, Antonella Bertazzo, and Carlo V. L. Costa. "Metabolism of Tryptophan Along the Kynurenine Pathway in Alloxan Diabetic Rabbits." In Advances in Experimental Medicine and Biology. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0135-0_45.

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Shanmuganathan, T., and A. V. P. Karthikeyan. "Evaluation of Anti-diabetic Activity of Cleome gynandra in Alloxan Induced Diabetic Wistar Albino Rats." In Phytomedicine. CRC Press, 2020. http://dx.doi.org/10.1201/9781003014898-18.

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Tenner, Thomas E., Xin Jian Zhang, and John B. Lombardini. "Hypoglycemic Effects of Taurine in the Alloxan-Treated Rabbit, a Model for Type 1 Diabetes." In Advances in Experimental Medicine and Biology. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0077-3_13.

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Shibata, Y., M. Hattori, F. Takeuchi, et al. "INFLUENCES OF FEEDING OYSTERS ON THE METABOLISM OF SEROTONIN IN ALLOXAN-DIABETIC RATS." In Progress in Tryptophan and Serotonin Research 1986, edited by David A. Bender, Michael H. Joseph, Walter Kochen, and Hans Steinhart. De Gruyter, 1987. http://dx.doi.org/10.1515/9783110854657-026.

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Conference papers on the topic "Alloxane diabetes"

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Caverina, Sarah Lorenza, Retno Yulianti, and Andri Pramesyanti. "Effectiveness of Soursop Leaf Extract to Decrease Malondialdehyde Level." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.05.07.

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ABSTRACT Background: In diabetes mellitus, hyperglycemia causes oxidative stress that enhances the production of free radicals. The presence of higher levels of malondialdehyde (MDA) indicates the rise of free radicals. On the basis of its role as an antioxidant that binds free radicals and reduces the level of malondialdehyde (MDA). Soursop leaf can act as an antidiabetic agent. This study aimed to examine the efficacy of soursop leaf extract (Annona muricata L.) to decrease the level of MDA level in alloxan-induced diabetic rats (Rattus norvegicus). Subjects and Method: This was an experimen
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Zhang, W., F. Liu, J. Seufert, and G. Päth. "Mesenchymal stem cells (MSC) reduce necrosis and apoptosis of pancreatic INS-1E beta cells during alloxan and streptozotocin exposure." In Diabetes Kongress 2018 – 53. Jahrestagung der DDG. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1641823.

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Wati, Linda, Linda Chiuman, Ali Napiah Nasution, and Chrismis Novalinda Ginting. "Anti-diabetic Activity of The Rose Petal Methanolic Extract in Alloxan-Diabetic Rats." In 2021 IEEE International Conference on Health, Instrumentation & Measurement, and Natural Sciences (InHeNce). IEEE, 2021. http://dx.doi.org/10.1109/inhence52833.2021.9537260.

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Al-Hayaly, Lekaa, Alaa Al-Sultan, and Saffa M. Sultan Sultan. "Effect of Olive Leaves Extract on Alloxan Induced Diabetes in Male Albino Mice." In Proceedings of the 1st International Multi-Disciplinary Conference Theme: Sustainable Development and Smart Planning, IMDC-SDSP 2020, Cyperspace, 28-30 June 2020. EAI, 2020. http://dx.doi.org/10.4108/eai.28-6-2020.2298148.

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Timoshina, Polina A., Rui Shi, Yang Zhang, et al. "Comparison of cerebral microcirculation of alloxan diabetes and healthy mice using laser speckle contrast imaging." In Saratov Fall Meeting 2014, edited by Elina A. Genina, Vladimir L. Derbov, Kirill V. Larin, Dmitry E. Postnov, and Valery V. Tuchin. SPIE, 2015. http://dx.doi.org/10.1117/12.2179988.

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"Antidiabetic effect of Ziziphus Jujuba fruit in Alloxan induced diabetic male rats." In International Conference on Medicine, Public Health and Biological Sciences. CASRP Publishing Company, Ltd. Uk, 2016. http://dx.doi.org/10.18869/mphbs.2016.61.

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Wu, Ming, and Li-Quan Guo. "Hypoglycemic Effects of Polysaccharides from Radix Astragali in Alloxan-Induced Diabetic Mice." In 2015 International Conference on Energy, Environmental & Sustainable Ecosystem Development (EESED 2015). WORLD SCIENTIFIC, 2015. http://dx.doi.org/10.1142/9789814723008_0157.

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Орусханова, Д. А., Т. А. Кринцова, А. В. Самотруев, А. А. Цибизова, М. У. Сергалиева, and М. А. Самотруева. "INFLUENCE OF SEMAX ON BEHAVIORAL REACTIONS WHITE RATS IN THE PORSOLT TEST UNDER EXPERIMENTAL ALLOXAN DIABETES." In Современные тенденции развития технологий здоровьсбережения. Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский институт лекарственных и ароматических растений", 2021. http://dx.doi.org/10.52101/9785870191027_2021_435.

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"Antidiabetic effect of Rosa canina L. fruit in alloxan induced diabetic male rats." In International Conference on Medicine, Public Health and Biological Sciences. CASRP Publishing Company, Ltd. Uk, 2016. http://dx.doi.org/10.18869/mphbs.2016.230.

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Hidayati, Dewi, Nurlita Abdulgani, Hengki Setiyawan, Indah Trisnawati, Nova Maulidina Ashuri, and Noor Nailis Sa’adah. "Analysis of protein profiles in diabetic rat blood plasma that induced by alloxan." In PROCEEDING OF INTERNATIONAL BIOLOGY CONFERENCE 2016: Biodiversity and Biotechnology for Human Welfare. Author(s), 2017. http://dx.doi.org/10.1063/1.4985407.

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