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1
Khardesh, Amani Ahmed F., Hitham Qasem M. Hadi, and Khaled Saeed Ali. "Antibacterial Activity of Aloe Lanata and Aloe Vacillanis Plant Extracts." Electronic Journal of University of Aden for Basic and Applied Sciences 1, no. 1 (2020): 20–24. http://dx.doi.org/10.47372/ejua-ba.2020.1.6.
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This study was conducted to evaluate the antibacterial effect of the aqueous and Methanolic extracts of Aloe Lanata and Aloe Vacillanis. Using agar diffusion method, three different concentrations of Aloe extracts were evaluated on Staphylococcus aureus, Escherichia. coli, Pseudomonas aeruginosa, and to compare the effectiveness of extracts with some antibiotics (Ampicillin: Amp, Erythromycin: Erytho, Gentamycin: Genta).The extracts showed that there was a different effect on the bacterial species according to the type and concentration of the plant extract as well as the inhibitory response to the bacterial species. The aqueous and alcoholic extract of A. lanata is more potent than A. vacillanis extract. In comparison to the type of extract, the alcoholic extract of A. lanata was more effective than the aqueous extract, while the aqueous extract of the A. vacillanis showed higher efficacy than the alcoholic extract. Both extracts had the most substantial effect on both E. coli and P. aeroginosa and were less effective on S. aureus. Antibacterial efficacy of studied plant extracts showed better efficacy than the antibiotic (Ampicillin, Erythromycin) on Staphylococcus aureus and E. coli.
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OSHOMOH, E. O., M. IDU, and I. E. EMEKA-KATANDU. "PHYTOCHEMICAL CONSTITUENTS AND ANTIMICROBIAL INVESTIGATION OF THE AQUEOUS EXTRACTS OF THE GEL AND LEAF OF Aloe vera (Aloe barbadensis MILLER) ON SELECTED MICROORGANISMS." Nigerian Journal of Life Sciences (ISSN: 2276-7029) 4, no. 2 (2022): 181–91. http://dx.doi.org/10.52417/njls.v4i2.198.
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Objectives: Phytochemical constitutents and antimicrobial property of the aqueous extract of the gel and leaf extract on some pathogenic microorganisms. The phytochemical determined include Tannins, Saponins, Flavonoids and Alkaloids. The gel of Aloe vera extract had its highest antibacterial activity on B. subtilis (23.33±0.88) and highest antifungal activity on C. albicans (16.00±2.31). While the leaf of Aloe vera extract had its highest antibacterial activity on B. substilis and S. aureus (21.33±0.88) and highest antifungal activity on C. albicans (21.00±3.22). Comparatively, the Aloe vera gel extracts showed better antimicrobial activity than the Aloe vera leaf extracts against the pathogenic microorganisms in the study. The antimicrobial activities of Aloe vera gel and leaf extracts were compared to those of orthodox antibiotics (Ciprofloxacin and Ketoconanzone). From the results, the Aloe vera plant (gel and leaf) extracts showed better antimicrobial activity than the orthodox antibiotics, therefore, Aloe vera plant extracts have shown to have the ability to overcome antibiotics resistances amongst microorganisms. Results of the study on the gel and leaf extracts of Aloe vera indicates its potential as a source of chemotherapuetic agent that may be useful in medicine.
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Safrida, Safrida, Devi Syafrianti, and Irma Haryani. "Effect of Aloe vera Extract in Reducing Formaldehyde in Salted Squid (Loligo indica) and Sensory Evaluation." E3S Web of Conferences 151 (2020): 01037. http://dx.doi.org/10.1051/e3sconf/202015101037.
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This study aims to determine the effect of Aloe vera extract in reducing formaldehyde levels in salted squid and determine the organoleptic characteristics of salted squid after being given Aloe vera extract. This study used a completely randomized design (CRD) with 4 treatments and 6 replications: P0 (0% Aloe vera extract), P1 (10% Aloe vera extract), P2 (20% Aloe vera extract), and P3 (30% Aloe vera extract). Data were analyzed by using an analysis of variants at a significant level α = 0.05 followed by Duncan's Test. The average formalin content before given aloe vera extract in P0, P1, P2, P3 was 3.65 mg / L, 4.08 mg / L, 4.09 mg / L, 3.96 mg/ L, respectively and after being given aloe vera extract was 2.75 mg/L, 2.58 mg / L, 1.63 mg / L, 2.82 mg / L, respectively. Administration of Aloe vera extract showed a significant reduction of formaldehyde levels in salted squid (p<0.05). Moreover, it was affecting the quality of salted squid in terms of color, aroma, and texture. It can be concluded that the administration of 20% Aloe vera extracts effective for reducing the formaldehyde levels, improve the quality of color, aroma, and texture in salted squid.
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Al-Mahbashi, Hassan Mohammed, and Hassan A. Al-Shamahy. "Cytotoxic Activities in Vitro of Flower Extracts of Three Species of Aloe Growing in Yemen: Aloe Rubroviolaceae, Aloe Vera and Aloe Sabaea, against Eleven Types of Cancer Cell Lines." Journal of Clinical Research and Reports 08, no. 05 (2021): 01–10. http://dx.doi.org/10.31579/2690-1919/187.
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ackground and aims: Natural products, especially plant extracts, have opened up great opportunities in the field of drug progress due to their chemical variety. The genus Aloe has long been used for medicinal uses in countless parts of the world. This study was designed to investigate the phytochemicals and anti-cancer capabilities of Aloe rubroviolaceae, Aloe vera and Aloe sabaea flowers. Materials and Methods: The methanolic extracts of three types of plants traditionally used in Yemen to treat a variety of diseases have been tested in vitro for their potential anticancer activity on different human cancer cell lines. The cytotoxic activity of the methanolic extracts of tested plants was determined using eleven strains of human cancer cells, namely: MCF-7 (breast cancer), PC-3 (prostate cancer), HEP-2 (human epithelial carcinoma), MNFS-60 (myelogenous leukemia), CACO (intestinal cancer), A-549 (lung adenocarcinoma), HeLa (cervical cancer), RD (rhabdomyosarcoma),HepG2 (hepatocellular carcinoma), HCT-116 (colon cancer), and CHO-K1 (Chinese hamster ovary). A colorimetric sulforhodamine B assay was used to evaluate the in vitro cytotoxic activity of different extracts. Growth inhibition of 50% (IC50) for each extract was calculated from the optical density of treated and untreated cells. Doxorubicin, a broad-spectrum anticancer drug was used as a positive control. Results: More interesting cytotoxic activity was observed for Aloe vera extract more than Aloe sabaea and Aloe rubroviolaceae, extract. Conclusions: This study provides a preliminary screening for anti-proliferative activity of various Aloe species flowers extracts on different cancer cell lines. Different extracts of Aloe species significantly inhibit the growth of various cancer cell lines in a concentration-dependent manner. Further investigations are required to understand the possible mechanism(s) of action of these extract on various cancer cells and isolation of active phyto-chemicals.
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Haque, Shammin, Ferdous Ara, Md Jalaluddin Iqbal, and Sheikh Nazrul Islam. "Effect of different extracts of Aloe Vera gel (Aloe Barbadensis) on blood glucose level of alloxan induced hyperglycaemic mice." Bangladesh Medical Journal 44, no. 2 (2016): 61–66. http://dx.doi.org/10.3329/bmj.v44i2.27239.
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This study was conducted to evaluate the effect of different extracts of Aloe Vera gel in alloxan induced hyperglycaemic mice.Three different extracts of Aloe Vera gel (dried extract, ethanolic extract and fresh raw extract) were orally administered at 300 mg/kg body weight for 28 days. The fasting blood glucose level was estimated both in normal and alloxan induced hyperglycaemic mice. It was found that, when compared with the control, there was a significant reduction in blood glucose level in all three experimental groups. Ethanolic and fresh raw gel extracts were more effective than the dried extract. The extracts produced similar results when compared with gliclazide. It can be concluded that, the administration of Aloe Vera gel extract significantly decreases blood glucose level in hyperglycaemic mice. Aloe Vera gel can therefore be a natural remedy and a cost effective resource for the management of diabetes.Bangladesh Med J. 2015 May; 44 (2): 61-66
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El-Banna, Heba, Samia A. Haroun, Tasahil S. Albishi, et al. "The Natural Alternatives: The Impact of Plant Extracts on Snowbush (Breynia disticha Forst.) Cuttings’ Morpho-Physiological and Biochemical Characteristics." Horticulturae 9, no. 10 (2023): 1122. http://dx.doi.org/10.3390/horticulturae9101122.
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The utilization of cuttings remains a prevalent method for vegetative propagation in various plant species. Synthetic rooting hormones have conventionally been employed to enhance the rooting process; however, their high cost and potential environmental risks have necessitated the exploration of natural alternative compounds. In this study, the efficacy of natural plant extracts (pure honey, aloe extract, willow extract, moringa extract, and cinnamon powder) and synthetic auxin derivatives (indole-3-butyric acid and α-naphthaleneacetic acid) at a concentration of 2000 ppm was compared for their influence on rooting and vegetative growth of snowbush (Breynia disticha) cuttings, a significant ornamental and medicinal shrub. Results demonstrated that while the synthetic hormones produced the highest survival percentages and root number, the roots were consistently short, thick, friable, and largely void of secondary roots. Conversely, the alternative natural plant extracts, particularly aloe extract, exhibited promising outcomes, showcasing good rooting percentage and root number, significantly increased root length, and fresh and dry root weight. Furthermore, aloe extract demonstrated the potential to enhance shoot length and alter the chemical constituents of the cuttings. The highest values of total phenols and nitrogen percentage were recorded with cuttings treated with indole-3-butyric acid, followed by cuttings treated with aloe extract. While using aloe extract, we recorded the highest values of total carbohydrates, phosphorus, and potassium percentages. Notably, the highest endogenous levels of indole acetic acid and gibberellic acid, along with the lowest abscisic acid concentration in cutting tissues, were associated with the highest rooting percentage observed with indole-3-butyric acid, followed by the use of aloe extract. We hypothesized that natural plant extracts, specifically aloe extract, have potential as a viable alternative for synthetic auxins in promoting successful rooting and vegetative growth in snowbush cuttings. Further research is warranted to explore the underlying mechanisms and optimize the application of these natural compounds in vegetative propagation techniques.
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Dibal, N. I., F. Buba, H. H. Laminu, et al. "The Protective Role of Aqueous and Methanol Extracts of Aloe Vera on Ethanol-Induced Kidney and Brain Injury in Mice." Sahel Journal of Veterinary Sciences 21, no. 4 (2025): 14–19. https://doi.org/10.54058/tsqn7b43.
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Impaired kidney function is associated with structural damage that usually cause negative effect to both human and animal health. It is associated with many complications such as anaemia, cardiovascular disease, and cognitive impairment. We evaluated the effect of aqueous and methanol extracts of Aloe vera (AV) on ethanol-induced kidney and brain injury in mice. Thirty mice were assigned to six groups (n=5) and received distilled water (control), 20% ethanol (negative control), (50 and 100) mg/kg methanol extract of Aloe vera plus ethanol, and (25 and 50) mg/kg aqueous extract of Aloe vera plus ethanol respectively for eighteen days. The mice were euthanized thereafter, and kidney function test was evaluated from the serum while oxidative stress markers were evaluated from the brain homogenate. One half of each brain was processed for light microscopy. The result showed that pretreatment with methanol and aqueous extracts of Aloe vera significantly reduced (p<05) the serum urea level relative to the ethanol-treated mice. The methanol extract (50mg/kg) and aqueous extract (25mg/kg) of Aloe vera significantly elevated (p<05) catalase activity relative to the ethanol-treated mice. Both the aqueous and methanol extracts of Aloe vera significantly reduced (p<05) malondialdehyde activity compared to the ethanol-treated mice. The cerebellum and cerebrum of the control mice and the mice pretreated with both the methanol and aqueous extracts of Aloe vera at 50mg/kg showed normal neurons. Conclusively,aqueous and methanol extracts of Aloe vera regulated serum urea levels, significantly increased brain catalase and reduced glutathione activities in ethanol-treated mice. It also prevented lipid peroxidation and neurodegeneration.
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Sari, Rafika, and Pratiwi Apridamayanti. "Determination of FICI Value of Combination of Ethanol Extract of Aloe Vera (L.) Burm. f. Leaf Peel and Chloramphenicol Against Bacterial Pathogens." Pharmaceutical Journal of Indonesia 9, no. 1 (2023): 9–13. http://dx.doi.org/10.21776/ub.pji.2023.009.01.2.
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The Increasing case of antibiotic resistance encourages a new action that is the combination plant extracts and antibiotics. Aloe vera leaf skin (Aloe vera (L.) Burm f.), contains phenols, flavonoids and anthraquinones that act as antimicrobials. The aim of research is to determine the value of FICI (Fractional Inhibitory Concentration Index) combination of ethanol extract of Aloe vera leaf skin (Aloevera (L.) Burm f.), and chloramphenicol against pathogenic bacteria. The determination of MIC (Minimum Inhibitory Concentration) value of ethanol extract for Aloe vera leaf skin (Aloe vera (L.) Burm. F.) and chloramphenicol use disc-paper diffusion method. The combination solution is created by a ratio of 1: 1 volumes from the every MIC values. The determination of FICI values was analyzed by descriptive. The combination of Aloe vera leaf skin extract (Aloe vera (L.) Burm. F.) and chloramphenicol are used for Salmonella typhi bacteria which are 12.5mg / ml and 8 μg / ml, and for Bacillus subtilis bacteria is 2.5 mg / ml and 4 μg / ml resulted in inhibit zone 7.77 ± 0.25 and 7.83 ± 0.36. The combination of FICI value is 2 and it has indifference characteristics (not different) when the researcherd compared between single extract and single chloramphenicol. Aloe vera leaf skin ethanol extract (Aloe vera (L.) Burm. f.) and chloramphenicol may inhibit the growth of Salmonella typhi and Bacillus subtilis bacteria and both of the combinations show indifference characteristics of FICI 2 values. Keywords: FICI, Aloe Vera, Antibacterial, Chloramphenicol.
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Kurniawan, Edy, Idham Halid, and Agustina Agustina. "Antibacterial Activity Of Plants Extract Drug Effective Against Pseudomonas aeruginosa Antibiotics Resistance To Quinolone And Cephalosporine." Medicra (Journal of Medical Laboratory Science/Technology) 5, no. 1 (2022): 35–39. http://dx.doi.org/10.21070/medicra.v5i1.1627.
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Antibiotics are empirically used as drugs to treat bacterial infections, but the irrational use of antibiotics causes bacterial resistance to certain antibiotic regimens, therefore solutions are needed to explore alternative drugs. This study aims to explore medicinal plants that are able to inhibit Pseudomonas aeruginosa bacteria that are resistant to quinolones and cephalosporins. The method used is descriptive observational and antibacterial activity test of plant extracts using the well diffusion method. Three plant extracts were used, binahong extract (Andredera cordifolia), tomato fruit extract (Lycopersicon esculentum), and aloe vera extract (Aloe vera). The results showed that only tomato extract inhibited Pseudomonas aeruginosa bacteria with a strong category, while binahong and aloe vera extracts could not inhibit the test bacteria. It was concluded that tomato fruit extract might be an alternative as a medicinal plant because it was able to inhibit P. aeruginosa resistant to quinolones and cephalosporin antibiotics.
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Kashari, O., Manga, S.B., Onwughara, C. A., Mohammed, H.K, and Bala, S.D. "Comparative Survey of Antibacterial Potency of Formulated Black Soap with Aloe Vera Extracts on Some Clinical Pathogens from the Skin." ChemClass Journal 9, no. 2 (2025): 356–67. https://doi.org/10.33003/chemclas-2025-0902/164.
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A comparative survey to determine the antibacterial potency of black soap formulated with Aloe vera and the Aloe vera extracts against some clinical pathogens (Staphylococcus aureus, Streptococcus pyogenes and Pseudomonas aeruginosa) of skin origin was carried out using agar "well" diffusion method. The Aloe vera formulated black soap and the Aloe vera extracts shows appreciable antibacterial potentials at all the concentrations (10%, 30%, 50% and 70%) used against the test organisms. The highest activity of 20.0 mm was recorded against S. aureus at the highest concentration of 70% used for the Aloe vera formulated soap and no activity was observed at the lower concentration against Ps. aeruginosa. Both the Aloe vera Gel and ethanolic leaf extracts recorded the highest activity of 18.0 mm against Ps. aeruginosa at the highest concentration of 70% used; no activity was recorded against S. aureus at lower concentrations used for both extracts and also no activity was observed against S. pyogenes for the Aloe vera ethanolic leaf extract. The MIC and MBC survey of the Aloe vera extracts and the formulated soap from Aloe vera indicates high antibacterial potentials against the test organisms except for the ethanolic leaf extract that fails to show any activity against S. pyogenes. The phytochemical survey of the extracts also revealed the presence of many important bioactive compounds including saponins, tannins and anthraquinones. These surveys have given a pointer to the possibility of using Aloe vera extracts for the formulation of skin care and skin remedies.
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Bhatnagar, Nupur, Mudit Sharma, and Farah Naz Faridi. "Antifungal Activity of Aloe Vera Extracts Against Phytopathogenic Fungus Aspergillus Spp." International Journal of Health Sciences and Research 12, no. 12 (2022): 86–91. http://dx.doi.org/10.52403/ijhsr.20221214.
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Medicinal plant contains many natural products to perform antifungal activity. The present study was undertaken to determine the antifungal activity of Aloe vera gel with ethyl acetate and methanol extracts against the Aspergillus spp. The fungus was isolated using standard potato dextrose agar. After identifying the fungus based on their morphology they were subjected to various biochemical tests. Gas chromatography-mass spectrometry (GC-MS) analysis was also performed to determine the content of Aloe vera gel with ethyl acetate and methanol extractions. The Aloe vera gel with methanol extract was found to have high yield as compared to ethyl acetate extract. The methanol extraction of Aloe vera also showed high inhibition rate of fungal flora as depicted by colony forming unit (CFU) method. Further studies are recommended to ascertain the role of Aloe vera with other solvent extracts as a potent pharmacological and therapeutic agent Key words: Antifungal activity, Aloe vera, extracts, GCMS
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Oktaviana, Marlia, Dwi Putri Rejeki, Ria Ceriana, Rosa Mardiana, and Sasmiati Farach Dita. "Formulasi Sediaan Lotion Dari Ekstrak Buah Alpukat (Persea Americana) dan Lidah Buaya (Aloe Vera) Untuk Kulit Kering." Journal of Pharmaceutical and Health Research 2, no. 2 (2021): 50–53. http://dx.doi.org/10.47065/jharma.v2i2.896.
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Skin care is needed so that the skin does not become dry, rough, and dull. The way to deal with dry skin is to use a scrub or use a moisturizer such as lotion. One of the active substances contained in lotion preparations is antioxidant compounds. Avocado and aloe vera extracts have antioxidant activity. Avocado and aloe vera have moisturizing benefits. In this study, both types of extracts were formulated into lotion preparations. Avocado and aloe vera extracts were made by maceration method using 70% ethanol as solvent. The extract was formulated with 3 variations, namely the control formula (F0), the avocado extract formula with a concentration of 5% (FI), and aloe vera with a concentration of 10% (F II). The lotion was tested for physical properties including pH, homogeneity, stability, spreadability and irritation tests. The results showed that the lotion containing avocado and aloe vera extracts with storage for two weeks was stable. Does not change shape, smell, color, and does not irritate the skin
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Narsih, Y. Erning Indrastuti, Desdy Hendra Gunawan, Saniah, and Borneo Satria Pratama. "Formulation and Characterization of Herbal Solid Soap Enriched with Cinnamon (Cinnamomum burmanii) and Aloe vera Peel Extracts." Indonesian Journal of Chemical Studies 4, no. 1 (2025): 14–21. https://doi.org/10.55749/ijcs.v4i1.66.
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This study aims to develop a solid soap formulation using natural ingredients by combining cinnamon (Cinnamomum burmanii) extract and Aloe vera peel extract, which are known for their antibacterial, antioxidant, and moisturizing properties. The research involved several stages, including the extraction of cinnamon and Aloe vera, soap formulation with varying cinnamon and Aloe vera extract concentrations, and testing of physicochemical properties and antibacterial activity against Escherichia coli. The formulated soaps were evaluated for moisture content, free alkali levels, pH, foam stability, antibacterial inhibition zones, and skin irritation. The results showed that increasing the concentrations of cinnamon and Aloe vera peel extracts significantly affected the soap’s characteristics. The optimal formulation was obtained with 15% cinnamon extract and 6% Aloe vera peel extract (A3B3), yielding a moisture content of 2.44%, free alkali content of 1.70%, pH of 11.8, and an antibacterial inhibition zone of 1.28 mm, without any skin irritation. FTIR analysis identified functional groups such as aldehydes, alkanes, aromatics, and hydroxyls, which were associated with the bioactive compounds responsible for antibacterial and moisturizing effects. The presence of cinnamaldehyde in cinnamon and saponins in Aloe vera contributed to the soap’s enhanced antimicrobial and skin-conditioning properties. Furthermore, Fourier-transform infrared spectroscopy (FTIR) analysis identified key functional groups responsible for the soap’s bioactivity. These findings suggest that incorporating herbal extracts into soap formulations can improve their functional benefits, making them a promising alternative for natural skincare products with antibacterial protection and skin health benefits.
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Huslina, Feizia. "PENGARUH EKSTRAK DAUN LIDAH BUAYA (Aloe vera L.) TERHADAP PERTUMBUHAN JAMUR Candida albicans SECARA IN VITRO." BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan 5, no. 1 (2017): 72. http://dx.doi.org/10.22373/biotik.v5i1.2977.
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The purpose of this study was to determine the ability of aloe vera leaf extract (Aloe vera L.) in inhibiting the growth of Candida albicans fungi through in vitro. Aloe vera (Aloe vera L.) is a plant that can overcome digestive problems caused by fungi. One of the pathogenic fungi causing gastrointestinal infections is C. albicans. This research was conducted in Microbiology Laboratory of FMIPAUnsyiah which lasted from April to May 2010. A Completely Randomized Design (RAL) consisted of 5 treatments and 5 replications is used in this study. The treatment was arranged on P0 = 20 μl distilled water, P1 = aloe vera leaf extract concentration 100%, P2 = aloe leaf extract concentration of 50% and P3 = aloe leaf extract concentration of 25%. Aloe vera leaf extract (Aloe vera L.) was given to each treatment at 20 μl. The parameter observed was the diameter of the inhibit zone formed. The data were analyzed using Variant Analysis (ANOVA), then continued with the Smallest Significant Difference (BNT) test. The results of this study indicated that the presence of aloe vera leaf extract (Aloe vera L.) could inhibit the growth of C. albicans. The higher the concentration of aloe vera leaf extract (Aloe vera L.), the higher the ability of it to inhibit C. albicans. The diameter of the inhibitory zone formed will enlarge along with the increasing of the concentration of aloe vera leaf extract (Aloe vera L.). The extract concentrations of 100%, 50% and 25% had their resistance capability of 0.50 mg, 0.24 mg and 0.20 mg of nistatin antibiotics.
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Khairi, Amalya Nurul, and Nurkhasanah Nurkhasanah. "Bioactive compounds content of Snake Fruit Peel, Aloe Vera, and Stevia Extracts as Raw Material of Functional Drinks." Journal of Agri-Food Science and Technology 1, no. 1 (2020): 34. http://dx.doi.org/10.12928/jafost.v1i1.1915.
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The objective of the research is to analyze the content of the bioactive compounds of extracts made of snake fruit skin, Aloe vera, and Stevia as materials to make functional drinks. Salacca zalacca (Gaert.) Voss. cultivar has flavonoid, tannin, and a bit of alkaloid on its fruit peel. Aloe vera and Stevia also known to have antioxidant compounds. Aloe vera controls the metabolism of carbohydrates and maintaining homeostasis of glucose. The research methods are divided into steps: 1) the extraction of Snake fruit peel, Aloe vera, and Stevia; 2) the formulation of the functional drink; 3)the evaluation of antioxidant, total phenol, and tannin levels of the formulated extracts. The research used Randomized Group Design (RGD) of two factors, and each factor consists of 4 levels and 2 levels. Factor I=the ratio of snake fruit peel:Aloe vera extract (10:90 (v/v); 30:70 (v/v); 70:30 (v/v); 90:10 (v/v)) and factor II= addition of Stevia filtrate (2%; 4%) (v/v total). The best nutrient of the formulated functional drink is obtained by the composition of 90% snake fruit peel extract, 10% aloe vera, and 4% stevia. The snake fruit peel extract significantly affects the antioxidant activity and total phenol composition, aloe vera extract has an insignificant effect on active compounds, and stevia affects the tannin level of the functional drink.
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Asma`a Mohsen Al-Wajih, Amina Mohammed El-Shaibany, Salwa Mohammed Raweh, and Mahmoud Mohamed El –Aasser. "Preliminary phytochemical screening for various secondary metabolites, quantitative and qualitative analysis of Yemeni Aloe vera and Aloe vacillans flower extracts." GSC Biological and Pharmaceutical Sciences 21, no. 2 (2022): 202–10. http://dx.doi.org/10.30574/gscbps.2022.21.2.0437.
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The name Aloe is from the Greek Aloe and refers to the bitter juice from the leaves of these plants. It is probably derived from the earlier Arabic word “Allah” meaning “shining bitter substance,” The bitterness results from the presence of aloin and Aloe-emodin, Aloe is referred to as the ‘Miracle Plant’ and ‘Healing Plant’. The Egyptians called Aloe “the plant of immortality. A comprehensive screening study will be carried out for the A. vera and A. vacillans flower collection from the Ibb government of Yemen. This study's main objectives are to identify, collected, shade dry, and Fraction the Aloe vera and Aloe vacillans flowers. Preliminary phytochemical screening to investigate the chemical composition of both extracts revealed the presence of flavonoids, phenolic compounds, carbohydrates, protein, and sterols in the methanolic extract of the Aloe Vacillans flower. Saponin, carbohydrate, flavonoid, steroids, protein, and phenolic compounds were found in the methanolic extract of the Aloe vera flower.
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Shobib, Ahmad, Priyono Kusumo, and Nurul Millah. "CHARACTERIZATION TEST OF BINAHONG (ANREDERA CORDIFOLIA (TEN.) STEENIS.) LEAVES AND ALOE VERA (ALOE VERA) LEAVES EXTRACTS USING INFUDATION METHOD IN MAKING LIQUID FOR EXTERNAL WOUND HEALING." Journal of Chemical Process and Material Technology 1, no. 1 (2022): 28. http://dx.doi.org/10.36499/jcpmt.v1i1.5896.
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Binahong leaves and aloe vera leaves contain flavonoid compounds and saponin compounds that can help the wound healing process, therefore a liquid medicine for external wound healing is made from extracts of binahong leaves and aloe vera leaves. The process of making liquid medicine begins with the manufacture of binahong leaf extract using binahong leaves carried out by the infundation method. The infundation method was carried out through an extraction process using distilled water at a temperature of (80-90)oC for 15 minutes. The results of the hypothesis show that at a temperature of (80-90)oC for 15 minutes there are no variables that affect the manufacture of binahong leaf extract. The binahong leaf extract and aloe vera were mixed according to the specified formula. The formulation used was the ratio (binahong leaf extract: aloe vera leaf) = 1:1 as formula A; 1:2 as formula B; 2:1 as formula C; 1.5:1 as formula D and added alcohol in the ratio (alcohol: a mixture of binahong leaf extract and aloe vera leaf) 1:4 to prevent oxidation. The preparation obtained is liquid so that it is easier to apply. The test results showed that the external wound healing liquid formulation with a volume ratio of aloe vera leaf extract and binahong 2:1 (Formulation C = 1.8467%) showed a high flavonoid content compared to formulas A, B, or D. The chosen method is that every 1 L of external wound healing liquid medicine consists of 536 ml of binahong leaf extract, 268 ml of aloe vera leaf extract, 201 ml of 70% alcohol from the total volume
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Singh, Pravanchana. "Screening of Antibacterial Efficacy of Aloe Barbadensis Miller (Aloe Vera) Using Leaf Extract against Different Bacterial Strains." International Journal for Research in Applied Science and Engineering Technology 9, no. VII (2021): 1872–75. http://dx.doi.org/10.22214/ijraset.2021.36705.
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The current research was aimed to evaluate in vitro antibacterial activity of crude extract prepared from leaves of Aloe vera plant. The extract of Aloe vera was prepared in Methanol. Two extracts were prepared, one from whole leaf powder and the other from fresh Aloe vera gel. To determine the antibacterial efficacy of the given plant, Kirby-bauer disk diffusion method was performed. The standard antibiotic used was Gentamicin. Gentamicin showed significant antimicrobial efficacy against E.coli and Bacillus subtilis forming a zone of inhibition of 34mm in both. This research provides information about antibacterial susceptibility of aloe vera leaves (leaf powder and fresh gel) against two different bacteria: E.coli which is a gram-negative bacteria and Bacillus subtilis which is a gram-negative bacteria. The antibacterial susceptibility test showed that the extract of leaf and the gel of Aloe vera inhibited the growth of both microorganisms during test. Growth of E,coli strain were inhibited more as compared to Bacillus subtilis because gram negative bacteria do not have lipopolysaccharide layer in their cell wall. Also the fresh gel Extract was more effective as compared to Aloe vera leaf powder.
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Parnomo, Trimurti, and Dame Joyce Pohan. "Test the Effectiveness of Aloe Vera Extract on the Growth of Escherichia coli in vitro." International Journal of Health Sciences and Research 11, no. 8 (2021): 211–24. http://dx.doi.org/10.52403/ijhsr.20210831.
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Aloe vera is a kind of living pharmacy and has an antibacterial power. The antibacterial substances are saponin, tannin and flavonoid. Previous studies indicate that Aloe vera extracts have antibacterial effects against the growth of positive Gram bacteria, either inhibiting harmful Gram bacteria. The experiment was intended to observe the antibacterial effects of Aloe vera against Escherichia coli colonies. The Aloe vera extract can be done through maceration methods in five concentrations (20%, 40%, 60%, 80% and 100%). The experiments were using Escherichia coli which was performed on MH agar by Kirby Bauer disc diffusion. The result showed a clear zone near the discs containing Aloe vera extracts in 100% concentration. So, it can be concluded that Aloe vera has an antibacterial effectivity against the growth of Escherichia coli colonies in vitro. Key words: Extracts, Aloe vera, Escherichia coli.
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Oigbochie, A. E., I. M. Moses-Otutu, and E. B. Odigie. "The use of Aloe barbadensis M. (Aloe vera) Extract as Potential Stains in Gram’s Staining Technique." Dutse Journal of Pure and Applied Sciences 8, no. 2a (2022): 47–56. http://dx.doi.org/10.4314/dujopas.v8i2a.6.
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Aloe barbadensis miller (Aloe vera) aside being a potent antioxidant with effects attributed to the phytoconstituents (anthraquinone), can also serve as natural dyes. This study explored the staining potentials of A. barbadensis extract on microbial specimens in modified Gram’s staining technique. The plant was washed; shrubby edges of the leaves were scraped off and each leaf cut open to expel the gel content. The dried and grinded leaf material weighing 450g was treated with two different extraction methods (150g for heated alcoholic aloe extract (HAAE) and 150g each for the unheated alcoholic aloe extracts I & II (UAAE-1 & UAAE-II). Preliminary phytochemical screening of extracts using bontragers test was conducted. Solutions from the two extraction methods with and without a mordant were applied on bacterial smears. Anthraquinone-rich extract under optimal extraction conditions were 10.0, 4.84 and 18.8 respectively. Comparing the extraction methods, HAAE and UAAE1 & UAAEII are mutually convenient and easy to make; but the former was more cost-effective with regards to power and instrumentation while the latter was more cost-efficient with regards to solvent. The pH of various prepared solutions was acidic and the extracts contained a bioactive agent that imparts pigment on biological specimens. In comparing the mordanted and non-mordanted solutions, the former had no additional effects on the staining efficiency of the aloe dye extract. We concluded that A. barbadensis dye visibly stained bacterial Gram positive and Gram negative cells in modified Gram’s staining without structural differentiations. We recommend reductions in staining duration for microbial samples to ascertain the reasons for the variation in staining uptake.
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Yılmaz, Ebru, Deniz Çoban, Birsen Kırım, and Mehmet Güler. "Effects of Extracts of Feed Additives Including Rosemary (Rosmarinus officinalis) and Aloe Vera (Aloe barbadensis) on the Growth Performance and Feed Utility of Nile Tilapia (Oreochromis niloticus)." Turkish Journal of Agriculture - Food Science and Technology 7, no. 6 (2019): 866. http://dx.doi.org/10.24925/turjaf.v7i6.866-870.2438.
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This study was performed to determine the effects of the extracts of two alternative antimicrobial agents that do not harm the ecosystem (rosemary, Rosmarinus officinalis and aloe vera, Aloe barbadensis) when added to the feed of tilapia (Oreochromis niloticus) on the growth performance, proximate composition, and biometric characteristics. Rosemary extract was added to the experimental diet in ratios of 0.1%, 0.25%, and 0.5% while aloe vera extract was added to the experimental diet in ratios of 0.5%, 1%, and 2.5%. After 90 days of the feeding trial, no change was seen in the weight increase, specific growth rate, feed conversion ratio, condition factor, hepatosomatic index, or viscerosomatic index of the tilapia. The fact that proximate analyses did not differ between groups showed that the plant extracts did not adversely affect the health status of tilapia in the ratios used in this study. As a result, the addition of 0.1%, 0.25%, and 0.5% rosemary extract and the addition of 0.5%, 1%, and 2.5% aloe vera extract to tilapia feeds did not cause changes in the growth performance, biometric indexes, or chemical composition findings of the fish meat.
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Pulliero, Alessandra, Aldo Profumo, Alberto Izzotti, and Sergio Claudio Saccà. "Release of Aloe vera Extracts from Therapeutic Lenses." Applied Sciences 10, no. 24 (2020): 9055. http://dx.doi.org/10.3390/app10249055.
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Aloe vera extracts have been used for drug therapy due to their antimicrobial, anti-inflammatory, and epithelia-regenerative actions. Considering the possible adverse side effects on the corneal surface of anti-microbial agent administration after ocular surgery, it is of interest to identify the ability of Aloe vera extract release from a therapeutic lens to prevent ocular irritation. The aim of this research was to evaluate the effects of different lens types on the availability and efficacy of releasing Aloe vera extracts in which they are soaked. Two lens types were examined: (1) non-ionic hydrogel lenses and (2) ionic hydrogel lenses. Aloe vera availability was quantified by LC–MS, and activity was quantified by a spectrophotometer (Nanodrop) at different times: (a) 30 min, (b) 60 min, (c) 2 h, (d) 6 h, and (e) 24 h. The lens allowing for the most abundant passage of Aloe vera extracts was the ionic hydrogel lens, followed by the non-ionic hydrogel lens. The obtained results demonstrate that the best lens allowing for the high and stable release of Aloe vera extract to the corneal surface are those composed of ionic hydrogels.
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Chauhan, Beenu Singh, Albha Tiwari, and Arti Bhadauria. "A study on phytochemical extraction of Aloe vera." INTERNATIONAL JOURNAL OF AGRICULTURAL SCIENCES 18, no. 2 (2022): 786–92. http://dx.doi.org/10.15740/has/ijas/18.2/786-792.
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Aloe vera is considered to evaluate over its properties to alleviate the dislipidemic and hyperglycemic conditions on animal models to raise fresh evidences, so that theplant or its extracts could be suggested confidently for its use for health endorsing potential medicinal plant. The preliminary phytochemical analysis of hydroethanolic extract of Aloe vera showed presence of phenols, tannin, steroids, terpenoids and glycosides. Total Phenol Content (mg GAE/g), Total Flavonoid Content (mg QE/g) of hydroethanolic extract of Aloe vera were, respectively 393.65 mg and flavonoid 334.947 μg/mg, respectively.
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Srisomboon, Surapong, Thanapong Intharah, Ungkarn Jarujareet, Arnit Toneluck, and Piyaphong Panpisut. "The in vitro assessment of rheological properties and dentin remineralization of saliva substitutes containing propolis and aloe vera extracts." PLOS ONE 19, no. 5 (2024): e0304156. http://dx.doi.org/10.1371/journal.pone.0304156.
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Saliva substitutes with enhanced dentin remineralization properties were expected to help manage caries progression in patients with xerostomia. This in vitro study examined the rheological properties and remineralization action of experimental saliva substitutes containing propolis extract and aloe vera extract on demineralized dentin. Four experimental saliva substitutes were formulated with varying concentrations of propolis extract (P) and aloe vera extract (A) were prepared. A commercial saliva substitute (Biotene Oral Rinse) was used as a commercial comparison. The rheological properties and viscosity of these materials were measured using a strain-controlled rheometer (n = 3). The remineralizing actions of saliva substitutes on demineralized dentin after 2 weeks were determined using ATR-FTIR and SEM-EDX (n = 8). The results were expressed as a percentage increase in the mineral-to-matrix ratio. Biotene demonstrated a significantly higher viscosity (13.5 mPa·s) than experimental saliva substitutes (p<0.05). The addition of extracts increased the viscosity of the saliva substitutes from 4.7 mPa·s to 5.2 mPa·s. All formulations showed minimal shear thinning behavior, which was the viscoelastic properties of natural saliva. The formulation containing 5 wt% of propolis exhibited the highest increase in the median mineral-to-matrix ratio (25.48%). The SEM-EDX analysis revealed substantial mineral precipitation in demineralized dentin, especially in formulations with 5 wt% or 2.5 wt% of propolis. The effect of the aloe vera extract was minimal. The addition of propolis and aloe vera extracts increased the viscosity of saliva substitutes. the addition of propolis for 2.5 or 5 wt% to saliva substitutes increased mineral apatite precipitation and tubule occlusion. To conclude, the saliva substitute containing propolis extract demonstrated superior remineralizing actions compared with those containing only aloe vera extract.
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Agusriani, Agusriani, and Halimatussa'diyah Halimatussa'diyah. "Inhibitory Test of Ointment Kalanchoe pinnata leaf Extract And Aloe vera Extract." Journal of Pharmaceutical And Sciences 5, no. 2 (2022): 240–49. http://dx.doi.org/10.36490/journal-jps.com.v5i2.117.
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Research that uses a combination of two plants is still very rarely done here, researchers are interested in conducting tests to see how the inhibitory ability of the ointment combination of Kalanchoe pinnata leaf extract (Kalanchoe pinnata) and aloe vera leaf extract (Aloe vera) is grown and cultivated in the yard of the Department of Pharmacy, Poltekkes, Ministry of Health. Jambi. The research design used is Quasy Experimental research, that is, this design has control, but cannot function fully to control external variables that affect the experiment. This study uses the Disc Diffusion method. Where it is known that the combination of Kalanchoe pinnata leaf extract ointment and Aloe Vera (Aloe Vera .L.) leaf extract obtained an average measurement of the clear zone of Staphylococcus aureus bacteria with a percentage of F1 is 29.6 mm, F2 is 30.2 mm, F3 is 30.8 , F4 is 31.6 and F5 is 33.8 mm. The different methods can affect the optimization of the withdrawal of the active substance in the leaves of Kalanchoe pinnata and Aloe Vera leaf obtained. So it can be concluded that the combination of Kalanchoe pinnata leaf extract and Aloe Vera leaf extract has an inhibitory effect on Staphylococcus Aureus bacteria. The best formula for the formula is F5 with an inhibition zone of 33.8 mm, which is categorized as very strong.
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Kurian, Bijo. "Comparison of antibacterial efficacy of herbal extracts of aloe vera leaves and mushroom against streptococcus mutansand lactobacillus - an in vitro study." RGUHS Journal of Dental Sciences 9, no. 1 (2017): 23–29. http://dx.doi.org/10.26715/rjds.9_1_4.
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BACKGROUND AND OBJECTIVES: This study evaluated and compared the antimicrobial efficacy and minimal inhibitory concentration (MIC) of chlorhexidine 0.12% and extracts of aloe vera and mushroom against Streptococcus mutans and lactobacillus. MATERIALS & METHODOLOGY: The agar disc diffusion and broth micro dilution method was used to check the antimicrobial activity of 0.12% chlorhexidine and aqueous extracts of two medicinal plants. The test samples were divided as follows- Streptococcus mutans, group I: chlorhexidine, group II: Aloe vera and group III: Mushroom. Lactobacillus, Group I: chlorhexidine, group II: Aloe vera extract and group III: Mushroom extract. The zone of inhibition and MIC values were tabulated and the data was statistically analyzed using ANOVA and Bonferroni post- hoc tests. RESULTS: Chlorhexidine shows maximum antibacterial action against Streptococcus mutans and lactobacillus followed by mushroom extract and aloe veraextracts with the zone of inhibition of (20.3mm/ 24.13), (17.03/ 16.05), (14.09/14.26) respectively. Both the extracts had MIC value of 80µg/ ml and chlorhexidine was 40µg/ml. CONCLUSION: Within the limitations of this in- vitro study, it can be concluded that all the herbal extracts tested in this study demonstrated antibacterial activity against MS and lactobacillus. Chlorhexidine showed maximum antibacterial action against Streptococcus mutans and lactobacillus followed by mushroom extract and then aloe veraextracts with the zone of inhibition of (20.3mm/24.13), (17.03/ 16.05), (14.09/14.26) respectively. Herbal products have potent antimicrobial activity that can be looked at as an alternative to chlorhexidine. However, further in vitro and long-term in vivo studies are recommended to confirm and correlate the findings of this study clinically.
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Jamal Abbas, Maha. "Evaluation the Inhibitory Effect of Aloe Vera Aqueous and Alcoholic Extracts on Salivary Streptococcus Mutans In Comparison to Chlorohexidine Gluconate." Tikrit Journal for Dental Sciences 1, no. 1 (2023): 124–35. http://dx.doi.org/10.25130/tjds.2015.1.17.
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diabetic properties. The aim of this study (an in vitro study) was to evaluate the effect of Aloe Vera alcoholic and water aqueous extract in different concentration (18%, 28%, 38%, and 48%) on the viable count and inhibition zone of streptococcus mutans and compared with chlorhexidine 2%. In this study the isolation and identification of streptococcus mutans was performed from saliva of individual, aged under 65 years old, these bacteria was isolated, purified and diagnosed according to morphological characteristic features and biochemical test. The effect of Aloe Vera extracts in different concentrations were tested on the isolated species by using agar diffusion technique and the effect of different concentrations of aloe vera on viable count of streptococcus mutans.Results: In vitro experiments, statistically reduction in the viable count of streptococcus mutans was recorded at all concentration of alcoholic Aloe Vera extract and increase in the concentration lead to increase in the reduction of viable count of streptococcus mutans while in this study showed significant reduction in viable count of streptococcus mutans at higher concentration of water extract of Aloe Vera at 38% and 48%.The diameter of inhibition zone of streptococcus mutans were highly significant at all concentration of alcoholic extract in comparison to water extract
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Rieuwpassa, Irene Edith, Rahmat Rahmat, and Karlina Karlina. "Mahasiswa tingkat kepaniteraan Universitas Hasanuddin Makassar, Indonesia." Journal of Dentomaxillofacial Science 10, no. 2 (2011): 65. http://dx.doi.org/10.15562/jdmfs.v10i2.256.
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The aim of this study was to determine the effectiveness of Aloe vera extract in inhibiting the growth ofStaphylococcus aureus and to measure the minimum inhibitory concentration (MIC) on the growth of the bacteria.The method using the manufacture of aloe extract, extract dilution, purified Staphylococcus aureus, MIC test andview the zone of inhibition. The results show that the (MIC) of Aloe extract was at concentration of 0.25. After astatistical test with ANOVA test on survey data (α<0.05), then the result obtained 0.000. This shows significantdifferences between various concentrations of Aloe vera extract in inhibiting the growth of Staphylococcus aureusbacteria. The higher the concentrationof Aloe vera extract, the more expand diameter of inhibition zone. Thusextracts of Aloe vera may be used to inhibit the growth of Staphylococcus aureus.
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Nailufa, Yuyun Nailufa,. "The Optimization of Cream Body Scrub with Black Rice Extract and Aloe Vera Extract." Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) 5, no. 02 (2024): 139. http://dx.doi.org/10.30587/herclips.v5i02.6903.
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Black sticky rice has a fairly high antioxidant. Black Sticky Rice Contains Vitamin B1, magnesium, iron and protein. It is can help maintain skin health and make skin look brighter. Aloe vera extract contains saponins contained in aloe vera gel can clean dirt from the skin. In addition, aloe vera also contains vitamin E which can potentially moisturize the skin. This study aims to designing formulas body scrub with herb black sticky rice and aloe vera extract and observe physical characteristics and physical stability for 3 months. Physical characteristic evalusion includes homogeneity test, organoleptis test, pH test, dispersion test and viscosity test. The stability test was carried out for 3 months of storage at room temperature and 40°C. The results showed that body scrub cream with black sticky rice and aloe vera extract on F2 was the most optimal formula and stable during storage of 90 days or 3 months.
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POP, Raluca M., Ion C. PUIA, Aida PUIA, et al. "Pot Aloe vera gel – a natural source of antioxidants." Notulae Botanicae Horti Agrobotanici Cluj-Napoca 50, no. 2 (2022): 12732. http://dx.doi.org/10.15835/nbha50212732.
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Aloe vera (Aloe barbadensis Miller) is widely spread around the world and it is used in the food and cosmetic industry and traditional medicine due to its high content in bioactive compounds. Thus, this article investigated the phenolic compounds of Romanian Aloe vera gel and its antioxidant capacity. The gel was extracted using 4 different solvents: methanol, ethanol, water, and acetone. Total phenolics were measured by the Folin-Ciocalteu method, total flavonoids by aluminium chloride reaction, and the antioxidant capacity by DPPH radical-scavenging activity. The profile of the phenolic compound was determined using Fourier transform infrared spectroscopy and Liquid Chromatography-Diode Array Detection–Electro-Spray Ionization Mass Spectrometry. The methanolic extract had a significantly higher antioxidant activity, followed by ethanolic, water, and acetone extracts. The methanolic extract had also the highest total polyphenol content, while ethanolic extract had the highest total flavonoid content. The extracts contained 14 compounds identified as 7 chromones (Aloesin, Neoaloesin, Aloinoside A, Aloinoside E, Aloe-emodin-glucoside, Isoaloeresin D, Methoxycoumaroyl-aloresin) 2 flavones (Luteolin-glucoside, Apigenin-glucoside), one hydroxycinnamic acid (Caffeic acid) and 4 to anthrones (Aloin A, Aloin B, Emodin, Aloe-emodin). The LC-MS results showed important quantities of Aloesin, Neoaloesin, Aloeresin E, and Aloe-emodin-glucoside while FTIR analysis showed the presence of polysaccharides, pectins, anthraquinones, and saponins.
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Pouyafard, Adeleh, Negin Jabbaripour, Abbas-Ali Jafari, and Fatemeh Owlia. "Investigating the Anti-fungal Activity of Different Concentrations of Aloe vera in Candida albicans Infection under In Vitro Conditions." Journal of Advances in Medical and Biomedical Research 31, no. 146 (2023): 268–74. https://doi.org/10.30699/jambs.31.146.268.
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<strong>Abstract</strong> <strong>Background and Objective: </strong>A variety of synthetic and chemical drugs have been established for the treatment of candidiasis, but each has some limitations and its probable side effects. This study attempts to touch upon the antifungal activity of different concentrations of hydroalcoholic extracts of <em>Aloe vera</em> against <em>Candida albicans</em> in <em>in vitro</em> conditions. <strong>Materials and Methods: </strong>Hydroalcoholic extract from <em>Aloe vera</em> leaves was tested for anti-fungal activity via an in vitro study. Anti-fungal activity and minimum inhibitory concentration (MIC) were determined by the disk diffusion method. <em>Aloe vera</em> hydroalcoholic extracts (75%, 50%, 25%, and 12.5%) were used as test groups. The data were analyzed by ANOVA using SPSS 23 software. The level of statistical significance was set at p≤ 0.05. <strong>Results:</strong> The results revealed that <em>Aloe </em>v<em>era</em> contained substantial anti-fungal activity. There was a significant discrepancy in the mean diameter of the inhibition zone of <em>C. albicans</em> growth among different concentrations of <em>Aloe vera</em> (p-value=0.001). Also, there was a statistically significant difference between the average diameter of the inhibition zone of <em>C. albicans</em> growth at a concentration of 12.5% of <em>Aloe vera</em> extract compared to concentrations of 25%, 50%, and 75% <em>Aloe vera,</em> and concentration of 50% with 25% and 75% extracts. <em>Aloe vera</em> extract at 75% concentration effectively inhibited the growth of <em>C. </em><em>albicans</em> compared with the positive control-nystatin. In this study, <em>Aloe vera</em> concentration of 20% was determined as the MIC for <em>C. albicans</em>. <strong>Conclusion: </strong>In adherence to the present results, it seems that <em>Aloe vera</em> extract, which is inexpensive and has no side effects, could be introduced as an alternative to nystatin. <strong>Keywords: </strong>In Vitro Techniques, Minimal inhibitory concentration, Aloe, Antifungal, Candida albicans
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Delladari Mayefis, Rury Trisa Utami, and Mulyani Ardian Ningsih. "Antiseptic Activity of Combination Lotion of Herbal Extracts of Gotu Kola (Centella Asiatica (L). Urban) and Aloe Vera Against Psedomonas Aeruginosa Bacteria." Formosa Journal of Sustainable Research 2, no. 9 (2023): 2389–400. http://dx.doi.org/10.55927/fjsr.v2i9.4765.
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To test the antibacterial activity of antiseptic gel, a combination of gotu kola herb extract and aloe vera extract against pseudomonas aeruginosa bacteria. Experimentally using the well diffusion method with a combined concentration of gotu kola and aloe vera herbal extracts of 5%:5% (F IV), 7.5%:2.5% (F V), 7.5%:2.5% (F VI), with positive control using antic antiseptic. The antibacterial activity with the antiseptic combination of gotu kola and aloe vera herbal extracts against pseudomonas aeruginosa bacteria has a medium category inhibitory power of 18.06 mm. The data obtained was tested for normality using the Shapiro Wilk test followed by the One Way Anova test. Based on statistical tests using ANOVA, it shows that there is a significant difference between the average percentage values between groups (sig ≤ 0.05). The single lotion activity and antibacterial combination of gotu kola and aloe vera herbal extracts can inhibit the growth of pseudomonas aeruginosa bacteria
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Swastini, I. Gusti Agung Ayu Putu, I. Gusti Agung Ayu Dharmawati, I. Gede Surya Kencana, and Ni Made Sirat. "SIFAT ANTIMIKROBA KOMBINASI SENYAWA KIMIA ANTARA EKSTRAK DAUN LIDAH BUAYA (Aloe vera L) DENGAN DAUN SIRIH (Piper bettle L) TERHADAP BAKTERI STREPTOCOCUS MUTANS PENYEBAB DENTAL PLAK." Jurnal Kesehatan Gigi (Dental Health Journal) 7, no. 2 (2020): 43–48. http://dx.doi.org/10.33992/jkg.v7i2.1258.
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Background: Plants that are medical and used for generations are aloe vera and betel leaf, which contain natural chemical and have antimicrobial and antiseptic properties.Objective: The purpose of this study was to calculate the growth inhibition zone of Streptococcus mutans by using the interaction of aloe vera extract and betel leaf, with a concentration of 50%, 75%, 100%.Method: This research was carried out at the Microbiology Laboratory of Udayana University using a pure experimental method of extracts of Aloe vera leaves and betel leaves with concentrations of 50%, 75%, 100%, seven repetitions, using Streptococcus mutans ATCC 35668, and isolation media for Mueller Hilton plus 5 % goat blood.Results: The average inhibition zone diameter in the interaction groups of aloe vera extract and betel leaf in each group was statistically significant difference (p 0.05), where the inhibitory concentration with the highest 100% concentration was an average of 82.6 mm with very strong criteria.Conclusion: The interaction of aloe vera leaf extract and betel leaf with a concentration of 100% has the highest inhibitory power of 82.6 mm, with very strong criteria.
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Marlina, Dewi, Minda Warnis, Fadly Fadly, Ade Agustianingsih, and Tedi Tedi. "FORMULA DAN UJI ANTIBAKTERI SABUN KERTAS EKSTRAK ETANOL DARI DAUN LIDAH MERTUA (SANSEVIERIA TRIFASCIATA P.) DAN DAUN LIDAH BUAYA (ALOE VERA L.)." JPP (Jurnal Kesehatan Poltekkes Palembang) 17, no. 1 (2022): 23–29. http://dx.doi.org/10.36086/jpp.v17i1.1129.
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Background: The form of soap that has not been widely circulated in the market is soap in sheet form or in paper form. The sheet form will provide an advantage, which is easy to store and can be carried anywhere, and the use of one sheet at a time can maintain the quality of the soap. One of the natural active ingredients that have an antibacterial effect are the leaves of the mother-in-law's tongue leaf plant (Sansevieria trifasciata Prain) and the aloe vera (Aloe vera L.) leaf extract. This study aims to formulate the Ethanol Extract of Aloe Vera Leaf (Sansevieria trifasciata Prain) and Aloe Vera Leaf Ethanol Extract (Aloe vera L.) into paper soap preparations that meet the requirements.
 
 Methods: The method used is experimental by making paper soap from mother-in-law's aloe leaf extract and aloe vera extract by making formulas I, II, III with 10%, 15% and 20% percentages of aloe vera extract, while the percentage of aloe vera extract is 3%, 6 % and 9%. And evaluation of the preparation was carried out for 28 days, and Test the effectiveness of Gram positive bacteria (Staphylococcus aureus) and Gram negative bacteria (Escherichia coli). Results: During 28 days of storage, the preparation of soap made from pH-stable paper tends to decrease as well as foam stability and free fatty acid content, but it still meets the requirements of SNI. The results of the organoleptic test of methamphetamine preparations made from paper did not change the smell and color, and did not irritate the skin, And has an inhibitory effect on the growth of Staphylococcus aureus bacteria.
 Conclusion: Paper soap with ethanol extract of mother-in-law's tongue (Sansevieria trifasciata p.) and ethanolic extract of aloe vera leaf (aloe vera L.) can be formulated into paper-based soap preparations that are stable and meet the specifications required by the Indonesian National Standard (SNI) and are able to inhibit growth. Staphylococcus aureus and Escherichia coli. The most optimal formula in Formula II with varying concentrations of a mixture of 15% aloe vera leaf ethanol extract and 6% aloe vera leaf ethanol extract .
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Arshad, Nimra. "Integrated Management of Leaf Spot of Aloe Vera Caused by Alternaria alternata through Chemicals and Plant Extracts." Phytopathogenomics and Disease Control 3, no. 2 (2024): 233–39. http://dx.doi.org/10.22194/pdc/3.1042.
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Aloe Vera (Aloe Barbadenisis Miller) plant used for centuries for its medicinal, beauty, health and skin care properties. It is a xerophytic, succulent, pea-green colored plant which contains vitamins, minerals, sugar, enzymes, lignin, salicylic acid, saponins and amino acids. Leaf spot of Aloe vera caused by Alternaria alternata, is the most significant fungal infection affecting commercial Aloe vera farming. Current study was designed to investigate the effects of chemicals and botanicals against leaf spot disease of Aloe vera. For this purpose, infected plants of Aloe vera were gathered Horticultural Research Area, UAF. The fungus was isolated, purified and identified at Phytopathology Laboratory. Five fungicides and plant extracts were used with three different concentrations under completely randomized design (CRD). The outcomes of current study indicated that, among tested plant extracts, Clove inhibited maximum mycelial growth (6.53 mm) followed by Garlic (9.52 mm), Turmeric (10.42 mm), Ginger (11.52 mm) and Black pepper (13.42 mm), whereas among fungicides Tilt showed significant inhibitory effects against pathogen with minimum mycelial growth (6.60 mm), while Champion was found least effective among fungicides having maximum fungal growth (13.71 mm). Moreover, under greenhouse conditions most effective phyto-extract (Clove), chemical (Tilt) and their amalgamation were applied on inoculated aloe vera plants and found that the combination expressed most effective results against disease with least disease severity percentage (9.92%), followed by solo application of Tilt (13.82%) and clove (23.82%). It was suggested that Tilt as solo application or in combination with clove extract could be used as effective remedy to control leaf spot disease of aloe vera, however for home gardens extract of clove is highly recommended due to non-toxic effects on human health.
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Alobedde, Farah, and Karkaz M. Thalj. "Evaluation of the Antioxidant and Inhibitory Activity of Aloe vera plant Extract (Fermented by Lactobacillus plantarum bacteria) Against the Pathogenic Bacteria Isolated from Diarrhea Infections." Tikrit Journal for Agricultural Sciences 24, no. 1 (2024): 246–62. http://dx.doi.org/10.25130/tjas.24.1.20.
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The current study aimed to isolate bacterial species from people suffering from diarrhea, diagnose them, and prepare the aqueous extract of Aloe vera plant, and ferment it by the locally-isolated Lactobacillus plantarum bacteria, and determining the presence of phenolic compounds before and after fermentation.The antioxidant activity was estimated using the FRAP method and the inhibitory activity against bacterial isolates causing diarrhea was also determined. The results showed that the pathogenic bacterial species causing diarrhea were Salmonella, E. coli. Shigella and Proteus.The lactobacillus bacteria isolated and diagnosed from local dairy samples was Lactobacillus plantarum that was used to ferment Aloe vera plant extract. The types of phenolic compounds identified and estimated in Aloe Vera extract were Chlorogenic acid, Caffiec acid, Cinnamic acid, Gallic acid, Coumaric acid, Vitexin and Syringic acid.The highest antioxidant activity was (48), which was found to be after fermentation, compared to its value before fermentation, which was (39). It was also shown that the highest inhibitory activity efficiency of the fermented Aloe vera extract was against pathogenic isolates from Non-fermented extrac
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Dilla Sastri Mara. "Testing The Effectiveness of Aloe Vera Ethanol Extract Cream on Wound Healing Incision in the Skin of Mice (Mus Musculus)." International Journal of Public Health Excellence (IJPHE) 1, no. 2 (2022): 114–224. http://dx.doi.org/10.55299/ijphe.v1i2.198.
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A wound is an injury to the skin structure of the underlying tissue that may or may not result in a loss of skin integrity. One of the plants used for wound healing is aloe vera ( Aloe vera ). The purpose of this study was to determine the effectiveness and the most effective concentration of aloe vera extract cream for wound healing in mice. This research is experimental research. Because in this study three concentrations of aloe vera extract cream were used 10%, 25%, 50%, and povidone iodine as comparison. From this study, it was found that 10% aloe vera extract cream could heal cuts in mice for 13.2 days. Aloe vera extract cream 25% can heal cuts in mice for 12.6 days. Meanwhile, 50% aloe vera extract cream can heal cuts in mice for 10.6 days. Povidone iodine which was used as a positive control healed cuts on the skin of mice for 12.6 days. The cream base used as a negative control was able to heal cuts in mice for 12.8 days. From this study it can be concluded that the preparation of aloe vera extract cream is effective in healing cuts in mice.
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Khayum, Nadia Amatul, Rima Semiarti, and Nelvi Yohana. "Perbandingan Efektivitas Daya Hambat Antibakteri Ekstrak Rimpang Jahe Merah (Zingiber officinale var rubrum) dengan Formula Obat Kumur Lidah Buaya Terhadap Pertumbuhan Bakteri Staphylococcus aureus." Andalas Dental Journal 7, no. 1 (2019): 44–51. http://dx.doi.org/10.25077/adj.v7i1.135.
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Red Ginger extract and Aloe vera mouthwash formulae have an antibacterial properties. The Red Ginger extract contains of gingerol, essential oil, terpenoid, fenol, flavonoid, and the Aloe vera mouthwash formulae contains of aloe berbadensis. This compound can be used in inhibition against the growth of Staphylococcus aureus that cause infections. The method of this research is a laboratory experimental. The Red Ginger extract prepared by maceration method with 96% ethanol solvent. The Aloe vera mouthwash formulae is the ready stock. Discs soaked into two groups solution for 15 minutes, then placed on MHA media contain Staphylococcus aureus to see the inhibition power. The result showed that the Red Ginger extract and Aloe vera mouthwash formulae show the inhibiting power with a strong category. The average diameter inhibiting power of Red Ginger extract is 10,75 mm and Aloe vera mouthwash formulae is 12,82 mm. Independent Sample T-test showed the significance value is 0,00 (p<0,05). The conclusion of this reasearch is that the Aloe vera mouthwash formulae is more effective than Red Ginger extract in inhibiting the growth of Staphylococcus aureus.
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Akib, Nur illiyin, Andi Nafisah Tendri Adjeng, Rahiswari Pramudita Lakasa, et al. "Physical Stability of Hair Tonic Contain Ethanol Extract Galangal (Alpinia galanga L.) Rhizome and Aloe Vera Leaf Filtrate (Aloe vera L.)." Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan 6, no. 2 (2020): 67. http://dx.doi.org/10.33772/pharmauho.v6i2.12054.
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AbstractFormulation and stability testing of hair tonic contain galangal rhizome (Alpinia galanga L.) ethanol extract and Aloe vera L. filtrate has been done as alternative for dandruff removal and hair growth. This study aimed to produce stable hair tonic. Galangal rhizome extract obtained by maceration method using ethanol and aloe leaf filtrate obtained by filtering. Extracts and filtrates characterized include water and ethanol soluble content, water and ash content. Hair tonic was formulated by mechanical mixing method with variations of galangal rhizome ethanol extract and aloe vera leaf filtrate which were 4% and 12.5%; 5% and 25%; 6% and 37.5%. Hair tonic prepared were tested for stability by cycling test method including organoleptic, homogeneity, pH, and viscosity. The characteristics of the galangal rhizome ethanol extract were 12% water soluble extract, 12% ethanol soluble extract, 3% water content, and 2% ash content. The characteristics of Aloe vera leaf filtrate were 10% ethanol soluble extract, 1.6% water soluble extract, and 1% ash content. Stability testing shows that hair tonic preparations are organoleptically stable and homogeneous. The pH values before and after cycling test for formulas A, B, and C were 5.27 to 5.34, respectively; 5.00 to 5.15; and 4.87 to 5.05. Viscosity before and after the cycling test for formulas A, B, and C were 1.178 to 1.676 cPs respectively; 1,306 to 1,883 cPs; and 2,148 to 2,296 cPs. It is concluded that hair tonic prepared are stable based on the requirements of Indonesian National Standard (SNI).
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Marcelo-Silva, João, Masego Ramabu, and Stefan John Siebert. "Phytoremediation and Nurse Potential of Aloe Plants on Mine Tailings." International Journal of Environmental Research and Public Health 20, no. 2 (2023): 1521. http://dx.doi.org/10.3390/ijerph20021521.
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Mine tailings are a source of potentially toxic metals (PTMs) worldwide. Phytoremediation is a low-cost green technology that uses metal-tolerant plants to extract these contaminants and rehabilitate the soil. In mine tailing restoration efforts, it can be beneficial to introduce species that can facilitate the colonization of other plants (i.e., nurse plant syndrome). In this study, the phytoremediation and nursing potential of two species adapted to metalliferous soil, Aloe burgersfortensis and A. castanea, were evaluated for the first time. An experiment was performed with aloe plants grown in pots containing potting soil, platinum tailings, and gold tailings. Leaves were assessed for bioaccumulation of PTMs. Seeds of Bermuda grass and African daisy, two successional pioneers, were planted with the aloes and had their developmental parameters evaluated after 30 days. Allelopathic effects were also assessed, with seeds of the pioneer plants infused with root extracts of the aloes from the different soil treatments. A. castanea demonstrated greater potential for the bioaccumulation of Cd, Co, Mn, Ni, and Zn in the tailings. The presence of aloes benefited germination rates, leaf count, length, and plant biomass of grasses and daisies in the mine tailings, without significant allelopathic effects. Therefore, aloes—especially A. castanea—should be employed in the rehabilitation of metal-contaminated soils to extract metals and to aid the establishment of other species to enhance the phytoremediation processes.
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Rokiman Letsara, Rigobert Andrianantenaina, Gédéon Ngiala Bongo, et al. "TLC Profiling of Leaves Extracts of Some Aloe Threatened Species Endemic to Madagascar for Their Antioxidant Activity." Britain International of Exact Sciences (BIoEx) Journal 2, no. 3 (2020): 653–62. http://dx.doi.org/10.33258/bioex.v2i3.304.
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The World Health Organization reported that at least 80% of populations rely on traditional medicine and medicinal plants for their primary health care. Due to their phytochemical compounds, the plants of the Aloe genus are reported to have high potential antiCovid-19 (and antioxidant properties. The aim of this study is to evaluate the in vitro antioxidant activity of some Malagasy endangered species of Aloe genus. The ethanolic extract of few Aloe of Madagascar leaf extracts was fractionated by liquid-liquid partition using hexane. In total 18 different fractions from 9 species have been used to determine their antioxidant activity through in vitro model by using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay. Both hexanic extract and aqueous extract displayed antioxidant activities in four species. The most evident antioxidant activity was expressed by A. helenae.
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Rezky Maulidiya and Ardi Mustakim. "Review Artkel Efek Sinergis Ekstrak Nabati terhadap Pengendalian Bakteri Patogen pada Produk Pertanian dan Kesehatan." Mikroba : Jurnal Ilmu Tanaman, Sains Dan Teknologi Pertanian 2, no. 1 (2025): 91–98. https://doi.org/10.62951/mikroba.v2i1.248.
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Vegetable ingredients are natural sources of active compounds that have the potential to be used as control agents for pathogenic microorganisms in various fields, including health and agriculture. This study aims to evaluate the synergistic effect between aloe vera (Aloe vera L.) and bandotan (Ageratum conyzoides L.) extracts on inhibiting the growth of pathogenic bacteria in different media. Aloe vera extract is obtained using the infundation method, while bandotan extract is obtained using the maceration technique. The concentrations tested were 30%, 45%, and 60% for each extract, as well as a combination of both. Testing was carried out on two main applications: as an antiseptic hand sanitizer by testing germ colonies using Plate Count Agar (PCA), and as a bacteria control Erwinia carotovora, the cause of carrot tuber rot, using the Path Ways Analysis test. The results showed that the combination of aloe vera and bandotan extracts had more significant inhibitory effectiveness than single extracts in both applications. A combination concentration of 60% gave the best results with a reduction in bacterial colonies of up to 90%. The mechanism of action of active compounds such as flavonoids, phenolics and saponins in this vegetable extract plays an important role in damaging bacterial cell membranes and inhibiting the metabolism of microorganisms. This research confirms the potential of using local plant materials as an environmentally friendly and economical solution for controlling pathogenic bacteria in the health and agricultural sectors.
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Umaraw, Pramila, Akhilesh K. Verma, V. P. Singh, and Ahmad Fahim. "Effect of Turmeric and Aloe Vera Extract on Shelf-Life of Goat and Buffalo Admixture Milk Paneer during Refrigeration Storage." Foods 11, no. 23 (2022): 3870. http://dx.doi.org/10.3390/foods11233870.
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The present study was undertaken to evaluate efficacy of turmeric and aloe vera extract in extending shelf life of goat milk paneer. The paneer was made by admixing goat milk and buffalo milk in the ratio of 60:40 so as to achieve a standard fat 4.5%. The treatment group, T1, was made by adding 5 mL/100 mL (v/v) of turmeric extract in heated milk before coagulation. Similarly, 5 mL/100 mL (v/v) aloe vera extract was added to heated milk for group T2 while T3 was prepared by adding both turmeric extract 5 mL/100 mL (v/v) and aloe vera extract 5 mL/100 mL (v/v), and the control was made without any additive. The extracts before incorporation were assessed for their antioxidant and antimicrobial potential by analysing total phenolic content, ABTS and DPPH percent inhibition and zone of inhibition. The developed paneer samples were evaluated for physico-chemical, oxidative and microbiological changes, and sensory attributes during storage at refrigeration temperature for ten days. The results revealed that paneer prepared with addition of extracts significantly (p < 0.05) suppressed physico-chemical deterioration. Significantly (p < 0.05) lower peroxide value, TBARS, FFA and microbial counts were noticed in T3 than T1, T2 and the control. The sensory attributes were also better (p < 0.05) maintained in T3 during storage. The results concluded that the combination of turmeric and aloe vera extract significantly improves the shelf life of paneer under refrigeration storage and these might be used as phyto-preservatives in paneer.
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Majid, Hina. "EFFECT OF ALOE VERA ON GROWTH OF RAT PUPS." Pakistan Postgraduate Medical Journal 29, no. 4 (2020): 155–57. http://dx.doi.org/10.51642/ppmj.v29i4.22.
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ABSTRACT: 
 Aim and Objective: Widely and commonly grown plant, Aloe vera has numerous health benefits. The breast fed neonates of mothers consuming the plant as dietary supplement are exposed to its effects. The objective of the research was to evaluate the effects of Aloe vera extract on growth of rat pups. Study design: Experimental study. Place of study: Anatomy department of Postgraduate Medical Institute, Lahore. Material and Method: A week old Wistar albino rats were fed with extracts of Aloe vera (low dose 50mg/kg b.w and high dose 500mg/kg b.w) daily for ten days through oral gavage. The weight of the pups was recorded and after euthanasia the lower limb region was dissected and tibia were removed. The length and weight of the bone was noted. Results: Pups fed with a high dose of Aloe vera extract showed a significant increase in their body mass (p<0.05) and also demonstrated a significant increase in the length of tibia (p<0.001). Conclusion: 500mg/kg b.w of Aloe vera extract resulted in a significant increase in the body weight and promoted the tibial bone growth.
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Ahluwalia, Bani, Maria K. Magnusson, Fredrik Larsson, Otto Savolainen, Alastair B. Ross, and Lena Öhman. "Differences in Metabolite Composition of Aloe barbadensis Mill. Extracts Lead to Differential Effects on Human Blood T Cell Activity In Vitro." Molecules 27, no. 19 (2022): 6643. http://dx.doi.org/10.3390/molecules27196643.
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Aloe barbadensis Mill. (Aloe) is used for diverse therapeutic properties including immunomodulation. However, owing to the compositionally complex nature of Aloe, bioactive component(s) responsible for its beneficial properties, though thought to be attributed to polysaccharides (acemannan), remain unknown. We therefore aimed to determine the metabolite composition of various commercial Aloe extracts and assess their effects on human blood T cell activity in vitro. Peripheral blood mononuclear cells (PBMC) from healthy donors were stimulated polyclonally in presence or absence of various Aloe extracts. T cell phenotype and proliferation were investigated by flow cytometry. Aloe extracts were analyzed using targeted 1H-NMR spectroscopy for standard phytochemical quality characterization and untargeted gas chromatography mass spectrometry (GC-MS) for metabolite profiling. Aloe extracts differing in their standard phytochemical composition had varying effects on T cell activation, proliferation, apoptosis, and cell-death in vitro, although this was not related to the acemannan content. Furthermore, each Aloe extract had its own distinct metabolite profile, where extracts rich in diverse sugar and sugar-derivatives were associated with reduced T cell activity. Our results demonstrate that all commercial Aloe extracts are unique with distinct metabolite profiles, which lead to differential effects on T cell activity in vitro, independent of the acemannan content.
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Subaidah, Windah Anugrah, Yohanes Juliantoni, and Wahida Hajrin. "Formulasi dan Evaluasi Sifat Fisik Lotion Ekstrak Etanol Daun Kemuning (Murraya paniculata (L) Jack) dan Daun Lidah Buaya (Aloe vera Linn)." Sasambo Journal of Pharmacy 1, no. 1 (2020): 12–16. http://dx.doi.org/10.29303/sjp.v1i1.6.
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The ultraviolet radiation and skin water loss could damage the skin. Kemuning leaves (Murraya paniculata (L) Jack) as a source of anti-oxidants and Aloe vera leaves (Aloe vera Linn) can prevent this action. This study aims to formulate and evaluate lotion containing the Kemuning leaves and Aloe vera extract. The extract of Kemuning leaves was obtained by sonication using 70% ethanol solvent. Aloe vera juice was obtained by smoothing the aloe vera gel then filtered using clean gauze. The kemuning leaves extract and aloe vera extract had formulated into lotion preparation. The physical properties of the lotion (homogeneity, type of emulsion, pH, spreadability, and adhesion) were determined. The organoleptic test showed that the color of the lotion was pale yellow with a smooth texture and had extract scent. The lotion was showed good homogeneity, spreadability 7.31 cm, pH 7, type oil in water and adhesion 45 seconds. The physical properties parameters of lotion preparations showed that the lotion preparations had fulfilled the requirements of good preparations.
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Xu, Yun Hui, and Li Chen. "Characterization on Aggregating Structure of Aloe Extract Crosslinked Cotton Fabric." Advanced Materials Research 311-313 (August 2011): 1132–35. http://dx.doi.org/10.4028/www.scientific.net/amr.311-313.1132.
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For exploiting the multifunctional ecological cotton textile products and developing the green modified technology for cotton fabrics, a novel cotton fabric with aloe extract crosslinking was prepared using citric acid as a crosslink agent under the pad-dry-cure procedure. Scanning electron microscopic photographs showed that the modification with aloe extract occurred on the surface of cotton fabric. FT-IR spectra of the modified fabric illuminated that aloe extract crosslinked with cotton fabric through the bridge linkage of citric acid after a series of reaction. The wide angle X-ray diffraction analysis indicated that the crystallinity of aloe extract modified cotton fabric slightly decreased. Furthermore, the changes in the aggregating structure and crystallinity were also reflected in the mechanical property studies of these modified fabrics. After treatment by aloe extract, the breaking strength and elongation of cotton fabric decreased. However, the moisture regain of the modified cotton fabric increased. The results obtained are useful in explaining structure-property correlations with respect to the aggregating structure and crystallinity, and suggest valuable information in planning applications for the aloe extract modified cotton textile products.
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Sidiq, Fahmi. "Review of the Healing Potential of Burn Wounds with Aloe Vera Extract Cream: The Influence of Formula and Virgin Coconut Oil Application." International Journal of Health, Medicine, and Sports 1, no. 4 (2023): 20–24. http://dx.doi.org/10.46336/ijhms.v1i4.19.
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This paper discusses the potential of using Aloe vera extract cream with various formulas, including the incorporation of Virgin Coconut Oil (VCO) as a cream base, for burn wound healing. The study aims to investigate the healing effects of second-degree burn wounds in mice using Aloe vera extract cream with different formulas. Phytochemical analysis identified the presence of phenols, tannins, and saponins in the Aloe vera extract. The results of the wound healing tests indicate that Aloe vera extract creams with different formulas have the potential to accelerate healing, with a healing time range of 8 to 14 days. Formulas containing VCO as a cream base showed faster healing, likely due to the medium-chain saturated fatty acid content in VCO that supports tissue regeneration. Aloe vera extract also possesses cleansing and antiseptic properties that can prevent infections in wounds. Although healing times varied among the different formulas, the main conclusion is that Aloe vera extract creams have the potential to support the healing of second-degree burn wounds.
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Milasanti, Yulia Asmindra, Ratih Tyas Widara, and Aldesra Fitri. "Uji Aktivitas Penyembuhan Luka Sayat Gel Ekstrak Etanol Lidah Buaya (Aloe Vera L.) pada Mencit Putih Jantan (Mus Musculus)." Journal of Pharmaceutical and Health Research 4, no. 3 (2023): 387–95. http://dx.doi.org/10.47065/jharma.v4i3.4415.
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Aloe vera (Aloe vera L.) is an herbal plant that contains phytochemicals such as tannins, saponins, flavonoids, and polyphenols, which are useful in healing cut wounds. The phytochemical content has antimicrobial, antibacterial, and antiseptic properties. Several research findings show wound healing activity in experimental animals that have been treated with aloe vera plant extract. This research aimed to make ethanol extract gel from aloe vera leaves and test cuts on male white mice (Mus musculus). The type of research used is true experimental design research. An incision wound was made on the back of the mouse with a length of 1 cm and a depth of 2 mm. The test animals used were 24 animals which were divided into 6 experimental groups, namely Positive Control (Bioplacenton), Negative Control (Without extract content), Base (Without aloe vera extract and preservatives), F1 (Aloe vera extract content 2.5%), F2 (Aloe vera extract content 5%), and F3 (Aloe vera extract content 7.5%). Statistical analysis of wound healing data was carried out using the One way ANOVA (Analysis of Variants) method, while the physical examination of the gel formulation was described descriptively. The statistical test results significantly affected wound healing in male white mice (p<0.05). There is a significant difference between the negative control and F3, p-value = 0.027. The best activity in the wound healing process is F3, with an average percentage of wound healing on the 7th day, F2 on the 8th day, and F1 on the 9th day.
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Asma`a, Mohsen Al-Wajih, Mohammed El-Shaibany Amina, Mohammed Raweh Salwa, and Mohamed El –Aasser Mahmoud. "Preliminary phytochemical screening for various secondary metabolites, quantitative and qualitative analysis of Yemeni Aloe vera and Aloe vacillans flower extracts." GSC Biological and Pharmaceutical Sciences 21, no. 2 (2022): 202–10. https://doi.org/10.5281/zenodo.7652804.
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The name <em>Aloe</em> is from the Greek <em>Aloe</em> and refers to the bitter juice from the leaves of these plants. It is probably derived from the earlier Arabic word “Allah” meaning “shining bitter substance,” The bitterness results from the presence of aloin and <em>Aloe</em>-emodin, <em>Aloe</em> is referred to as the ‘Miracle Plant’ and ‘Healing Plant’. The Egyptians called <em>Aloe</em> “the plant of immortality. A comprehensive screening study will be carried out for the <em>A. vera</em> and <em>A.</em> <em>vacillans</em> flower collection from the Ibb government of Yemen. This study's main objectives are to identify, collected, shade dry, and Fraction the <em>Aloe vera</em> and <em>Aloe</em> v<em>acillans</em> flowers. Preliminary phytochemical screening to investigate the chemical composition of both extracts revealed the presence of flavonoids, phenolic compounds, carbohydrates, protein, and sterols in the methanolic extract of the <em>Aloe</em> <em>Vacillans</em> flower. Saponin, carbohydrate, flavonoid, steroids, protein, and phenolic compounds were found in the methanolic extract of the <em>Aloe vera</em> flower.