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1

Zillmer, Juliana Graciela Vestena, Isabel Cristina Arrieira, Teila Ceolin, Rita Maria Heck, and Rosa Lía Barbieri. "UTILIZAÇÃO DA BABOSA NO COTIDIANO DE USUÁRIOS PORTADORES DE CÂNCER." Revista Baiana de Saúde Pública 34, no. 4 (2011): 773. http://dx.doi.org/10.22278/2318-2660.2010.v34.n4.a70.

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O estudo teve como objetivo investigar a utilização da Aloe spp. pelos usuários portadores de câncer, no tratamento da doença. Trata-se de um estudo qualitativo, descritivo e exploratório, realizado em um município do Sul do Rio Grande do Sul com onze usuários portadores de câncer internados no Programa de Internação Domiciliar Interdisciplinar (PIDI) Oncológico. Destes, nove sabiam sobre a possibilidade de utilização da Aloe spp. para o câncer e apenas três referiram sua utilização para auxiliar no tratamento. A Aloe spp. foi utilizada pelos usuários, visando auxiliar no tratamento do câncer, sem abandonar o tratamento convencional. Concluiu-se que, apesar de os entrevistados terem relatado o uso da babosa, não se encontraram estudos que confirmassem suas propriedades anticancerígenas.
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2

Bhatnagar, Nupur, Mudit Sharma, and Farah Naz Faridi. "Antifungal Activity of Aloe Vera Extracts Against Phytopathogenic Fungus Aspergillus Spp." International Journal of Health Sciences and Research 12, no. 12 (2022): 86–91. http://dx.doi.org/10.52403/ijhsr.20221214.

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Medicinal plant contains many natural products to perform antifungal activity. The present study was undertaken to determine the antifungal activity of Aloe vera gel with ethyl acetate and methanol extracts against the Aspergillus spp. The fungus was isolated using standard potato dextrose agar. After identifying the fungus based on their morphology they were subjected to various biochemical tests. Gas chromatography-mass spectrometry (GC-MS) analysis was also performed to determine the content of Aloe vera gel with ethyl acetate and methanol extractions. The Aloe vera gel with methanol extract was found to have high yield as compared to ethyl acetate extract. The methanol extraction of Aloe vera also showed high inhibition rate of fungal flora as depicted by colony forming unit (CFU) method. Further studies are recommended to ascertain the role of Aloe vera with other solvent extracts as a potent pharmacological and therapeutic agent Key words: Antifungal activity, Aloe vera, extracts, GCMS
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3

Krynitskaya, Alla, Aniurka Maria Panfet Aulan, Elena Petukhova, Maria Kharina, and Zosya Kanarskaya. "Endophytic microorganisms of Aloe vera." E3S Web of Conferences 486 (2024): 07007. http://dx.doi.org/10.1051/e3sconf/202448607007.

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Aloe vera is one of the most commonly used plants in medical and pharmaceutical practice due to the large number of biologically active compounds it contains. At the same time, the internal gel of plants contains endophytic microorganisms that can increase the area of plants action. In the process of carrying out research work, the isolation and identification of microorganisms associated with the internal gel of Aloe vera was carried out. A method for aseptic shedding of microbial isolates from plant gel has been developed. Using the developed method, four microbial isolates were obtained. Morphological, cultural and physiological-biochemical analysis of the isolated microorganisms was carried out. Based on their characteristics, all isolated microorganisms can be attributed to the Actinobacteria class. Previously isolated bacteria can be identified as Arthrobacter spp. or Micrococcus spp. Additional research is required for more accurate identification. As a result of the research, the antimicrobial activity of two isolates against bacteria of the genus Bacillus was discovered.
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4

Eze, C. N., H. O. Stanley, and C. C. Nwankwo. "Effect of Plant Extract on Pathogens Isolated from Water Source." International Journal of Pathogen Research 12, no. 4 (2023): 11–26. http://dx.doi.org/10.9734/ijpr/2023/v12i4232.

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This study was designed to evaluate the effect of Aloe barbadensis Miller (Aloe vera) and Cymbopogon citratus (Lemongrass) extracts on pathogenic bacteria isolated from surface and ground water samples in Port Harcourt Metropolis. Samples of Aloe vera and Lemon grass were collected, pre-treated and extracted using n-hexane and ethanol respectively. The plant extracts were qualitatively and quantitatively assessed for their phytochemical properties using standard methods. Surface and ground water samples were collected and characterized for their physico-chemical and microbiological properties using standard methods. The pathogenic bacteria isolated from the water samples were subjected to antibacterial susceptibility tests using selected commercial antibiotics and the plant extracts respectively. Result revealed the presence of eight phytochemicals namely alkaloid, flavonoid, saponnin, tannin, glycoside, steroid, phenol and terpene in both hexane and ethanol extracts of the Lemongrass and Aloe vera with varying degrees. Four bacterial pathogens namely Streptococcus spp., Shigella spp., Pseudomonas spp. and Staphylococcus spp. were identified in the water samples. All of them were susceptible to both hexane and ethanol extracts of the Lemongrass and Aloe vera plants with zones of inhibition ranging from 10.2 mm to 14.5 mm and 16.7 mm to 20.9 mm and 4.2 mm to 9.5 mm and 6.7 mm to 11.2 mm, respectively. Commercial antibiotics such as Ciproflox, Streptomycin, Chloramphenicol and Cuntamycin were active against all the bacteria pathogens, with zones of inhibition ranging from 15.7 mm to 21.2 mm, 13.2 mm to 21.3 mm, 3.1 mm to 14.5 mm and 3.3 mm to 14.7 mm, respectively. The antibacterial action of ethanol extract of the Lemongrass on all four pathogens was comparable to that of commercial antibiotics such as Ciproflox, Streptomycin and Ofloxacin which also demonstrated higher antibacterial action on the pathogens. This study has revealed the usefulness of Aloe vera and Lemongrass plants in phyto-antibiotics and phyto-medicine.
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5

Bhowmik, Susmita, Runa Akter Chowdhury, and Md Aftab Uddin. "Microbiological analysis and detection of anti-bacterial activity of Centella asiatica and Aloe vera samples collected from different areas of Dhaka city, Bangladesh." Stamford Journal of Microbiology 6, no. 1 (2017): 39–43. http://dx.doi.org/10.3329/sjm.v6i1.33518.

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The present study was performed to detect the presence of contaminating microorganisms in two commonly available herbal samples (Centella asiatica and Aloe vera) collected from different areas of Dhaka city, Bangladesh and to assess their antibacterial activity. Out of twenty samples (having ten samples of each categories) studied; the range of total viable bacterial count was approximately 103 to 108 cfu/g. Presence of Staphylococcus aureus was found in all the samples, followed by Klebsiella spp. in 15 samples, Pseudomonas spp. in 14 samples, Bacillus spp. in 12 samples, Escherichia coli in 9 samples and Vibrio spp. in 7 samples. Salmonella spp. was detected in neither of the sample. 17 samples showed a high fungal load up to 107 cfu/g. Antibacterial activity of C. asiatica samples was demonstrated against eight laboratory isolates. Only four C. asiatica samples showed activity against Klebsiella spp. On the contrary, Aloe vera samples (12-14) showed antibacterial activity only against Staphylococcus spp.Stamford Journal of Microbiology, Vol.6(1) 2016: 39-43
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6

Laib, Imen, Fairouz Boubrik, and Malika Barkat. "Optimization of the extraction parameters of Aloe Vera polyphenols and study of antioxidant and antifungal activities: application to molds isolated from durum wheat." Acta Scientifica Naturalis 6, no. 1 (2019): 79–90. http://dx.doi.org/10.2478/asn-2019-0011.

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Abstract The main objectives of this work are to optimize the extraction parameters, to test the antioxidant activity of Aloe Vera extract and to study the impact of this extract on deteriorating molds of Algerian variety of wheat (CIRTA). The extraction was optimized by central composite design. Determination of the polyphenols, flavonoids, and proanthocyanidins was performed by using colorimetric assays. Identification and quantification of phenolic compounds were performed by RPHPLC-UV method. The antioxidant activity was tested by three methods: 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,20-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), and CUPRAC (Cupric reducing antioxidant capacity), the antifungal activity of Aloe Vera extract on isolated strains from durum wheat were tested by dilution in a solid medium method. The optimum of total phenolic got was1,044 x 104 µg GAE/g of dry extract. The extract is rich in polyphenols, flavonoids, and proanthocyanidins. The analysis of phenolic compounds of Aloe Vera by RP-HPLC-UV revealed seven phenolic compounds. Strong antioxidant activity was obtained for Aloe Vera extract. Purification and microscopic study of isolated strains gave the possibility of identifying four strains: Alternaria spp1, Alternaria spp2, Penicillium spp, and Aspergillus spp. the antifungal potential of Aloe Veravaries according to the fungal genera and the concentrations of extract used.
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7

Fouché, Morné, Clarissa Willers, Sias Hamman, Christiaan Malherbe, and Jan Steenekamp. "Wound Healing Effects of Aloe muth-muth: In Vitro Investigations Using Immortalized Human Keratinocytes (HaCaT)." Biology 9, no. 11 (2020): 350. http://dx.doi.org/10.3390/biology9110350.

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The traditional use of Aloe spp. for the purpose of wound healing has a long history and is widespread internationally. Recently, a hybrid aloe plant (Aloe muth-muth) has been cultivated by cross pollination between Aloe vera and Aloe ferox. The Aloe muth-muth plant has not yet been investigated for medicinal properties and provides an opportunity for potential biological activity, including wound healing. The aim of this study was to investigate the in vitro wound healing effects of both Aloe muth-muth gel and whole leaf material with the use of the immortalized human keratinocyte (HaCaT) cell line. Cell viability was conducted using methyl thiazolyl tetrazolium (MTT) assays. In vitro wound healing was tested on HaCaT cells using an established scratch assay method. The effect of Aloe muth-muth gel material on HaCaT cell migration was also investigated. Aloe muth-muth gel material exhibited statistically significantly (p < 0.05) higher percentage wound closure compared to the control at all three concentrations investigated. These findings confirm that this newly cultivated species, Aloe muth-muth, also possesses wound healing activity corresponding to that reported for the two species it is derived from, namely, Aloe vera and Aloe ferox. Therefore, Aloe muth-muth has the potential to be used in future wound therapeutics.
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8

Molero, Tamara, and Said Kas-Danouche. "Estimation of aloin concentration in Aloe vera L. (Aloe barbadensis Mill.) by mathematical modeling." Revista de la Facultad de Agronomía, Universidad del Zulia 39, no. 1 (2022): e223913. http://dx.doi.org/10.47280/revfacagron(luz).v39.n1.13.

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Aloin is one of the secondary metabolites that gives plants of the genus Aloe spp. their healing properties. The concentration of aloin is related to the fresh mass and, its industrial purification involves laboratory processes that add extra costs to its commercialization. The objective of this research was to mathematically modelize the estimation of the aloin concentration in A. vera L. from the fresh mass. The theory of discrete perfect least squares approximations was used, considering linear and exponential approximation functions. For the tabulation of the data, the option of class mark and the average of the values were used. The analyses of the approximations indicate that the exponential curves approximate the data better (with R2 = 75% and 82% for the two options, respectively) than the straight lines (with R2 = 65% and 70% for the two options, respectively). The use of these approximations is recommended to estimate the concentration of aloin in A. vera plants based on their fresh mass, facilitating the measurement of this secondary metabolite, and minimizing costs in the industrialization process.
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9

Alesa Gyles, Desireé, Anivaldo Duarte Pereira Júnior, Lorena Diniz Castro, et al. "Polyacrylamide-Metilcellulose Hydrogels Containing Aloe barbadensis Extract as Dressing for Treatment of Chronic Cutaneous Skin Lesions." Polymers 12, no. 3 (2020): 690. http://dx.doi.org/10.3390/polym12030690.

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Chronic wounds are severe breaks in the skin barrier that fail to heal in an acceptable time-frame, thus preventing the complete restoration of the tissue’s anatomical and functional integrity, increasing the likelihood of infections and apoptosis. Hydrogels are known as a drug delivery system and have the potential to cover wounds and burns on the skin. Aloe barbadensis contains over 75 different bioactive compounds which are responsible for its anti-inflammatory and antimicrobial properties. In this study, the polyacrylamide-co-methylcellulose hydrogel containing Aloe barbadensis were developed. The extract was prepared from lyophilized Aloe barbadensis, using methanolic extraction, characterized by high performance liquid chromatography and incorporated into the hydrogels. These Aloe barbadensis hydrogels were characterized by degree of swelling, Fourier-transform infrared spectroscopy, scanning electron microscopy, and thermal profiling using thermogravimetric analysis. The minimum inhibitory concentration test was done on the Aloe barbadensis extract to evaluate its antibacterial and antifungal activity in vitro. The Aloe barbadensis hydrogels and were shown to swell to almost 2000% of their original sizes. The Fourier-transform infrared spectroscopy indicated the presence of bands characteristic of Aloe barbadensis and hydrogel polymers. The basic hydrogel showed greater thermal stability than the hydrogels with Aloe barbadensis. The minimum inhibitory concentration showed inhibition of the growth of S. aureus and Salmonella spp. at specific concentrations. The hydrogel therefore presents itself as an excellent potential curative cover of cutaneous lesions.
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10

Akaberi, Maryam, Zahra Sobhani, Behjat Javadi, Amirhossein Sahebkar, and Seyed Ahmad Emami. "Therapeutic effects of Aloe spp. in traditional and modern medicine: A review." Biomedicine & Pharmacotherapy 84 (December 2016): 759–72. http://dx.doi.org/10.1016/j.biopha.2016.09.096.

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11

Salim, Hussein, Majida Alsaady, Abdulsattar Al-zuhairi, and Fahmy Kassoub. "Evaluation of the fungicidal activity of the aqueous extracts of some medicinal plants against Fusarium spp." Bionatura 8, no. 2 (2023): 1–9. http://dx.doi.org/10.21931/rb/2023.08.02.84.

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To assess the performance of the aqueous extracts of Rhus coriaria, Boswellia carterii, Nigella sativa and Aloe vera. Three concentrations (5%, 10%, and 15%) for each extract were tested in vitro for their activity against three isolates of Fusarium spp. All extracts have a high inhibitory capacity against tested isolates. An inhibition percentage for selected isolates was increased with concentrations (5%, 10%, 15%). The concentration of Rhus coriaria extract 15 % resulted in a significant increase in inhibition percentage of mycelial growth of Fusarium sp.1 (63.17%), Fusarium sp2 (61.69%) and Fusarium sp3 (59.35%) compared to other concentrations, the concentration of Boswellia carterii extract 10% led to a significant increase in inhibition percentage of mycelial growth of Fusarium sp2 (82.45 %) compared to concentration 5% (73.67 %), the concentration of Nigella sativa extract 15% was recorded high inhibition percentage in Fusarium sp2 (66.15 %) compared to concentration 5% (22.21%). In contrast, concentrations 5% and 10% were recorded highest inhibition percentages in Fusarium sp3, reaching 31.73 % and 22.02%, respectively, compared to concentration 15% (4.90%). Keywords: Rhus coriaria, Boswellia carterii, Nigella sativa, Aloe vera and Fusarium spp
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12

Suresh Barge, Monika, T. K. Narute, A. M. Navale, et al. "Isolation, Characterization of Azotobacter and PSB from Xerophytic Plants of Maharashtra State, India." International Journal of Current Microbiology and Applied Sciences 12, no. 9 (2022): 195–204. http://dx.doi.org/10.20546/ijcmas.2023.1209.019.

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The present study was conducted at Department of Plant Pathology and Agricultural Microbiology, MPKV, Rahuri during year 2021 to 2023 to characterize and screen different isolates of Azotobacter and PSB from Different Xerophytic plants from Different districts of Maharashtra State.68 Azotobacter isolates were biochemically characterized and screened under In- vitro conditions for their plant growth promoting properties. The highly efficient Azotobacter isolates was characterized by its nitrogenase activity, which was 189.4 nmol C2H4. mg protein-1.h-1 in Azt 2 (Zizipus spp) isolates, Out of sixty eight Azotobacter isolates, 3 isolates viz., Azt- 2 (Ziziphus spp), Azt-17 (Aloe spp), Azt- 8 (Agave spp), recorded significantly higher nitrogenase activity. The amount of Pi released from tri- calcium phosphate (TCP) by the isolates at 10 day after inoculation was ranged from 18.5 to 29.65 %. The quantitative estimation of per cent inorganic phosphorus released from Tri- calcium phosphate had recorded highest for PSB-4 (Zizipus spp) which was 29.65 % Thus, isolate PSB-4 (Zizipus spp) i.e. efficient strain isolated from ber was found to be significantly superior over rest of the isolate in solubilizing phosphate.
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13

Meléndez-Pizarro, Carmen O., Arlet Calva-Quintana, José C. Espinoza-Hicks, Miguel Á. Sánchez-Madrigal, and Armando Quintero-Ramos. "Continuous Flow UV-C Irradiation Effects on the Physicochemical Properties of Aloe vera Gel and Pitaya (Stenocereus spp.) Blend." Foods 9, no. 8 (2020): 1068. http://dx.doi.org/10.3390/foods9081068.

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Physicochemical properties of a blend of 10% Aloe vera gel with 5% pitaya juice subjected to UV-C doses of 16.5, 27.7, and 40 mJ/cm2 were evaluated at pH 3.5 and 5.5. Unprocessed treatments were used as the control. The a* color parameter decreased and luminosity increased at pH 3.5. The decrease in the reddish color was consistent with the decrease in total betalains content and stabilized at pH 5.5. The NMR analyses of UV-C treatments showed changes in betalains signal patterns. Polyphenolics content was significantly reduced in the UV-C treatments at pH 5.5. UV-C processing decreased the antioxidant activity 1.25 times compared to unprocessed treatments. Total sugar content was reduced as the UV-C dose increased. Doses above 16.5 mJ/cm2 resulted in a higher simple sugar content at a pH 3.5. The UV-C continuous flow technology can be applied to stabilize betalains in Aloe vera–pitaya blends at a UV-C dose of 16.5 mJ/cm2 and pH 5.5.
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Domenico Prisa and Marco Gobbino. "Microbic and Algae biofertilizers in Aloe barbadensis Miller." Open Access Research Journal of Biology and Pharmacy 1, no. 2 (2021): 01–09. http://dx.doi.org/10.53022/oarjbp.2021.1.2.0019.

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The aim of this work was to develop an organic and sustainable cultivation protocol, based on the use of microbial biofertilizers (Plant Growth Promoting Rhizobacteria, Trichoderma spp., arbuscular mycorrhizae and biostimulant algae) able to improve the growth and quality of Aloe barbadensis Miller plants. The experimental trial at CREA-OF in Pescia showed a significant improvement in the agronomic parameters analysed on Aloe barbadensis Miller plants treated with microbial and algae-based biofertilizers. In particular, there was a significant improvement in the number of leaves per plant, new shoots, vegetative fresh weight, root weight and gel weight. On the leaves in the treated theses, there was a significant increase in leaf length and width and an improvement in gel quality (optical density). The trial also showed a significant improvement in soluble solids, sugars and fibre content in the theses inoculated with microbial products and a significant increase in fructose, glucose, proline and aloin. These improvements in plant growth following the use of microbial biofertilizers and algae have also been found in previous trials in other vegetables and ornamental crops, but few trials have been carried out with Aloe. The application of symbiotic microorganisms in agricultural operations can therefore ensure higher production standards, with a possible improvement in the agronomic quality of the plants, while also reducing the use of water and fertilizers. This experiment may be of particular interest to farms that want to focus on the production of ornamental and fruit cacti and succulents under organic farming methods.
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15

Laub, Annegret, Ann-Katrin Sendatzki, Götz Palfner, Ludger A. Wessjohann, Jürgen Schmidt, and Norbert Arnold. "HPTLC-DESI-HRMS-Based Profiling of Anthraquinones in Complex Mixtures—A Proof-of-Concept Study Using Crude Extracts of Chilean Mushrooms." Foods 9, no. 2 (2020): 156. http://dx.doi.org/10.3390/foods9020156.

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High-performance thin-layer chromatography (HPTLC) coupled with negative ion desorption electrospray ionization high-resolution mass spectrometry (DESI-HRMS) was used for the analysis of anthraquinones in complex crude extracts of Chilean dermocyboid Cortinarii. For this proof-of-concept study, the known anthraquinones emodin, physcion, endocrocin, dermolutein, hypericin, and skyrin were identified by their elemental composition. HRMS also allowed the differentiation of the investigated anthraquinones from accompanying compounds with the same nominal mass in the crude extracts. An investigation of the characteristic fragmentation pattern of skyrin in comparison with a reference compound showed, exemplarily, the feasibility of the method for the determination of these coloring, bioactive and chemotaxonomically important marker compounds. Accordingly, we demonstrate that the coupling of HPTLC with DESI-HRMS represents an advanced and efficient technique for the detection of anthraquinones in complex matrices. This analytical approach may be applied in the field of anthraquinone-containing food and plants such as Rheum spp. (rhubarb), Aloe spp., Morinda spp., Cassia spp. and others. Furthermore, the described method can be suitable for the analysis of anthraquinone-based colorants and dyes, which are used in the food, cosmetic, and pharmaceutical industry.
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16

Zapata, P. J., D. Navarro, F. Guillén, et al. "Characterisation of gels from different Aloe spp. as antifungal treatment: Potential crops for industrial applications." Industrial Crops and Products 42 (March 2013): 223–30. http://dx.doi.org/10.1016/j.indcrop.2012.06.002.

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17

Velázquez Arellano, María Elena, Juan Roberto Benavente Valdés, Jesús Antonio Morlett Chávez, and Cristóbal Noé Aguilar González. "Producción de pigmentos por Monascus spp. en medio sólido empleando residuos agroindustriales." Investigación y Ciencia de la Universidad Autónoma de Aguascalientes, no. 69 (December 31, 2016): 89–95. http://dx.doi.org/10.33064/iycuaa2016691875.

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En esta revisión se describen los principales factores que afectan la producción de pigmentos por Monascus en medio sólido, así como los diferentes residuos utilizados y aquellos potenciales remanentes regionales en México que pueden ser aprovechados en la producción de pigmentos. Los colorantes producidos por el hongo Monascus han mostrado potencial aplicación en las industrias alimentaria, cosmética, farmacéutica y textil. La producción de pigmentos por Monascus se ha llevado a cabo principalmente en cultivos en estado sólido, para lo cual el uso de residuos agroindustriales como fuente de sustrato es una alternativa real que incrementa la factibilidad económica del proceso, aunado a ser una alternativa de bajo impacto ambiental. Los factores de temperatura, pH, humedad relativa y tamaño de partícula se identificaron como los factores de mayor influencia en la producción de pigmentos. Los residuos regionales de maíz, arroz y Aloe vera son los sustratos con mayor rendimiento.
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18

MOTOHASHI, K., T. AOKI, and T. KOBAYASHI. "Foot rot disease of Aloe spp. caused by Fusarium dimerum Penzig var. dimerum, a new disease." Japanese Journal of Phytopathology 73, no. 4 (2007): 304–8. http://dx.doi.org/10.3186/jjphytopath.73.304.

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19

Aldayel, Tahany S., Mary H. Grace, Mary Ann Lila, Mohammed A. Yahya, Ulfat M. Omar, and Ghedeir Alshammary. "LC-MS characterization of bioactive metabolites from two Yemeni Aloe spp. with antioxidant and antidiabetic properties." Arabian Journal of Chemistry 13, no. 4 (2020): 5040–49. http://dx.doi.org/10.1016/j.arabjc.2020.02.003.

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20

Jodhani, Kaushik A., and M. Nataraj. "Synergistic effect of Aloe gel (Aloe vera L.) and Lemon (Citrus Limon L.) peel extract edible coating on shelf life and quality of banana (Musa spp.)." Journal of Food Measurement and Characterization 15, no. 3 (2021): 2318–28. http://dx.doi.org/10.1007/s11694-021-00822-z.

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Goncalves, Estefany, Federico Casimiro-Soriguer Solanas, Javier García-Caballero, and Noelia Hidalgo-Triana. "Terrestrial Alien Flora of the Iberian Alboran Coast: Assessment, Attributes, and Future Implications." Diversity 15, no. 11 (2023): 1120. http://dx.doi.org/10.3390/d15111120.

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Although Mediterranean coastal regions in southern Spain have high floristic diversity and numerous Habitats of Community Interest (HCIs) identified by the European Union Directive Council, they are also vulnerable to invasive plants. In our study, we aimed to create a checklist of terrestrial alien taxa in the Iberian area of the Alboran coast, assess each species’ current invasion, analyse the influence of environmental attributes on invasion, estimate the richness of alien species per HCI group, and evaluate each species’ potential invasiveness based on its reproductive and dispersal attributes. The checklist that we developed includes 123 alien taxa, most belonging to the Asteraceae, Asparagaceae, and Poaceae families. Notably, 20% of the species are super invaders that occupy more than 20% of HCIs. We also identified Aloe vera, Cylindropuntia spp., Agave salmiana, Opuntia spp., and Paspalum spp. as incipient invaders with the potential for future expansion. Although most alien flora in the HCIs are not regulated by Spanish legislation (RDL 630/2013), monitoring and eradication plans are crucial. Advocating the cessation of using those plants in gardens and reducing anthropogenic pressure are also essential, as human activities worsen invasion dynamics and facilitate the introduction and establishment of invasive species.
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Allami, Risala H., Raghad S. Mouhamad, Sura A. Abdulateef, and Khlood abedalelah al-Khafaji. "Antimicrobial Activity of Herbal Mixture Extract Combination on Microorganisms Isolated from Urinary Tract infection." Bionatura 5, no. 4 (2020): 1346–51. http://dx.doi.org/10.21931/rb/2020.05.04.11.

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Urinary tract infection (UTI) is the second most common infection after respiratory tract infection. Its prevalence is more in women as compared to men. Approximately 50% of women have an infection of the Urinary tract in their life-time. The bacterial infection is one of the most important bioactivity; using their ability to imitate evanish then distributes international fitness problems into the 21st centenary. Thus a recent study was undertaken to investigate the antibacterial activity of a mixture of three medicinal plants against UTI infectious isolates. The three considered plants were (Aloe vera, Artemisia herba alba and Teucrium polium), which were used in Iraqi medicine for many centuries. The effectiveness of this combination was investigated using in vitro well diffusion method. The extract was tested against four isolated pathogenic bacteria (Staphylococcus aureus, Klebsiella spp, and Proteus spp). The aqueous extract exhibited antibacterial activity against gram-positive and gram-negative bacteria. The mixture extract had the highest effect against S. aureus and Proteus spp, followed by a lower effect on Klebsiella spp. In conclusion, the antibacterial effect of the tested plant extracts confirmed a higher impact on Gram-positive bacteria as compared to Gram-negative bacteria. Therefore, it can be concluded that the usage of these plants as a traditional medicine form can be considered as a strong assistant to regular medicine drugs and treatments.
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Malatji, Dikeledi Petunia, Tondani Madeleine Ramantswana, and Maphuti Betty Ledwaba. "The Control of Gastrointestinal Parasites of Village Chickens in Africa Using Ethnoveterinary Intervention: A Systematic Review." Veterinary Sciences 12, no. 5 (2025): 407. https://doi.org/10.3390/vetsci12050407.

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Gastrointestinal parasites have been reported to have negative effects on chickens reared in rural areas in African countries. Hence, smallholder farmers use ethnoveterinary remedies to control these parasites in village chickens. This study used online databases (ScienceDirect, PubMed, and Google Scholar) to search, gather, and review articles published between January 1990 and June 2024 where ethnoveterinary intervention was considered to control gastrointestinal parasites, following PRISMA guidelines. A total of 540 articles were generated, and only 17 articles passed the screening process and were considered for further analysis. The findings of this review indicate that ethnoveterinary remedies are used by smallholder farmers to control gastrointestinal parasites such as Ascaridia galli, Capillaria spp., Choanotaenia infundibulum, Eimeria spp., Heterakis gallinarum, and Raillietina cesticillus in village chickens. Aloe spp., Carica papaya, Musa paradisiaca, and Venonia amygdalina were reported as the most-preferred medicines, and farmers utilized different plant parts ranging from leaves (48.8%), bark and roots (12.2%), tubers (7.3%), and seeds (4.9%). These remedies are administered per os, topically, and dermally. The current review successfully summarized ethnoveterinary intervention used by smallholder farmers to control gastrointestinal parasites in chickens found in African countries. Therefore, there is a need to investigate the efficacy of these identified ethnoveterinary medicines against gastrointestinal parasites in chickens.
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Leite, Cindy V., and Gisele L. Oliveira. "Plantas Medicinais Cultivadas e Utilizadas na Associação Casa de Ervas Barranco da Esperança e Vida (ACEBEV), Porteirinha, MG." Revista Fitos 7, no. 01 (2012): 26–36. http://dx.doi.org/10.32712/2446-4775.2012.134.

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O conhecimento sobre uso tradicional de plantas medicinais pode auxiliar na descoberta de princípios ativos com alguma ação farmacológica. O objetivo deste trabalho foi levantar informações sobre as plantas cultivadas e utilizadas para fins medicinais na Associação Casa de Ervas Barranco da Esperança e Vida (ACEBEV), no município de Porteirinha, MG. Realizou-se uma entrevista semi-estruturada e diálogos informais com a Irmã Mônica, freira fundadora e responsável pelo local, para obtenção das informações. Este estudo mostrou que são cultivadas na ACEBEV 74 espécies medicinais, distribuídas em 33 famílias, destacando-se a Asteraceae (15 spp.) e Lamiaceae (15 spp.). As plantas medicinais são manipuladas de forma artesanal e comercializadas como medicamento natural. Os usos mais descritos estão relacionados às doenças infecciosas, da pele e tecido sub-cutâneo, transtornos do sistema nervoso e transtornos do sistema gastrintestinal. Aloe vera (2,0), Ricinus communis (2,0) e Kalanchoe brasiliensis (2,0) apresentaram os maiores valores de Importância Relativa. Os resultados do estudo mostram a importância da ACEBEV para a população local, tanto como apoio à saúde quanto para valorização e preservação dos recursos na região.
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da Silva, W. L., and R. Singh. "First Report of Alternaria alternata Causing Leaf Spot on Aloe vera in Louisiana." Plant Disease 96, no. 9 (2012): 1379. http://dx.doi.org/10.1094/pdis-04-12-0343-pdn.

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Aloe vera (L.) Burm. f. is a perennial succulent plant that is grown worldwide mainly for medicinal and cosmetic uses. In the USA, it is mainly cultivated in some southern states to produce aloe gel for the cosmetic industry (3), and in Louisiana it is also sold commercially as an ornamental. During the summer of 2011, several A. vera plants infected with leaf spots were observed on the campus of Louisiana State University, Baton Rouge. Large, necrotic, sunken, circular to oval, dark brown spots were present on both surfaces of the leaves. Infected leaf tissue pieces were surface disinfested with 1% NaOCl solution for 1 min and plated on potato dextrose agar (PDA). Plates were incubated at 28°C in the dark for 4 days. A dark olivaceous fungus with profuse golden brown, branched, and septate hyphae was consistently isolated from the infected tissue on PDA. The fungus produced conidia with longitudinal and transverse septa, and was morphologically identified as an Alternaria sp. (4). Conidia were produced in long chains, pale to light brown, obpyriform, with a beak (6.0 μm long), one to seven transverse and up to three longitudinal septa, and measured 10 to 45 μm long × 7 to 18 μm wide. Conidiophores were straight, septate, light to olive golden brown with conidial scar, and measured 35 to 100 μm long × 2 to 5 μm wide. Genomic DNA from a single-spored isolate was extracted and the internal transcribed spacer (ITS1-5.8s-ITS2) regions were amplified and sequenced using primers ITS1 and ITS4. BLASTn analysis of a 486-bp sequence (GenBank Accession No. JQ409455) resulted in 100% homology with A. alternata strain DHMJ16 (GenBank Accession No. JN986768) from China and several other Alternaria spp. The fungus was identified as A. alternata based on mycelial and conidia characters after being grown under standard, previously described conditions (4). Pathogenicity tests were carried out by inoculating six potted aloe plants with 0.5-cm diameter discs taken from a 6-day-old culture grown on PDA. Four discs were placed on the upper surface of each of the bottom leaves of every plant. Inoculated plants were individually covered with a plastic bag and maintained in a greenhouse for 1 week at 25 ± 2°C. Six control plants received only agar plugs. Seven days after inoculation, necrotic leaf spots were observed on the inoculated plants and A. alternata was reisolated from these spots. No leaf spots were observed on control plants. To the best of our knowledge, this is the first report of leaf spot caused by A. alternata on A. vera in Louisiana. Several outbreaks of the disease have been reported in Pakistan and India as damaging aloe gel production in those countries (1,2). An outbreak of this disease in Louisiana could represent a serious issue for the state's A. vera ornamental commerce. References: (1) R. Bajwa et al. Can. J. Plant Pathol. 32:490, 2010. (2) A. Kamalakannan et al. Australas. Plant Dis. Notes 3:110, 2008. (3) T. Reynolds. Aloes: The Genus Aloe. CRC Press, Boca Raton, FL, 2004. (4) E. G. Simmons. Alternaria: An Identification Manual: Fully Illustrated and with Catalogue Raisonné 1796-2007. CBS Fungal Biodiversity Centre, Utrecht, The Netherlands, 2007.
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Thapa, Bishnu, Anjana Singh, and Reshma Tuladhar. "In vitro Antibacterial Effect of Medicinal Plants Against Multidrug Resistant Gram Negative Bacteria." Tribhuvan University Journal of Microbiology 5 (September 26, 2018): 25–31. http://dx.doi.org/10.3126/tujm.v5i0.22298.

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Objectives: The aim of this work was to determine the antibacterial activity of methanol extract of herbal plants against the Multidrug resistant (MDR) Gram negative bacteria isolated from clinical samples.
 Methods: Gram negative bacteria isolated from various clinical samples were processed for antibiotic susceptibility test by modified Kirby-Bauer disc diffusion method and MDR bacteria were selected. Methanol extracts of six different medicinal plants Acorus calamus (bojho), Ocimum sanctum (tulsi), Azadirachta indica (neem), Cinnamomum tamala (tejpatta), Aloe vera and Zanthoxylum alatum (timur), were tested for antibacterial activity against the selected MDR bacteria by agar well diffusion method.
 Results: From clinical samples, 8 different MDR Gram negative bacteria isolated were Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Citrobacter spp., Proteus mirabilis, Proteus vulgaris, Acinetobacter spp. and Pseudomonas spp. with E. coli dominated the number. Out of six medicinal plants extracts, Z. alatum, C. tamala and Ocimum sanctum were found to be effective with zones of inhibition ranging from 9-13 mm. The medicinal plants with antibacterial activity can be an alternative source of medicine against MDR Gram negative bacteria.
 Conclusion: Several herbal plants extracts exhibit antibacterial activity against MDR Gram negative bacteria. Antibacterial activity of plant extracts can vary with type of plant and extraction methods. Thus, for optimal benefit of plant extract, an appropriate extraction method and use of purified product is essential.
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Seleteng-Kose, Lerato Esther, Puseletso Likoetla, and Lisebo Motjotji. "Plants of Commercial Importance in Lesotho: Ethnobotanical and Pharmacological Insights." Cosmetics 10, no. 1 (2023): 28. http://dx.doi.org/10.3390/cosmetics10010028.

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Several plants have been processed in Lesotho to manufacture various commercial prodcts, ranging from cosmetics and beverages (juice, tea) to traditional herbal mixtures and crafts. Even though plants of commercial importance have been documented in different regions and countries, this is not the case in Lesotho. Therefore, the aim of the study is to record plant species commonly used in the country for development of commercial products. A physical survey was undertaken in different places in the Maseru District of Lesotho between January 2019 and October 2021, taking a record of existing commercial products and identifying plants used in their development. A total of 15 plants of commercial importance in the country are recorded in the current study, namely Agave americana, Aloe ferox, Artemisia afra, Cannabis sativa, Helichrysum odoratissimum, Hemannia depressa, Hypoxis hemerocallidea, Leudeboria cooperi, Mentha spp., Merxmuellera spp., Pelargonium sidoides, Opuntia ficus-indica, Rosa rubiginosa and Urtica urens. Most of the plants are used for production of commercial products in the country, whereas some are exported as raw materials, mainly to countries such as Germany, South Africa, Australia and America. The latter are C. sativa, Merxmuellera spp., P. sidoides and R. rubiginosa. Profiling of the plants provides important information about their commercial potential. However, conservation of the plants is encouraged to ensure their sustainable utilisation.
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Silva, Leonardo Vitor Alves da, Isaac Feitosa Araújo, Roberta Maria Arrais Benício, et al. "Plantas exóticas na Chapada do Araripe (Nordeste do Brasil): ocorrência e usos." Revista Brasileira de Geografia Física 15, no. 3 (2022): 1239. http://dx.doi.org/10.26848/rbgf.v15.3.p1239-1259.

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Plantas exóticas ocorrem no Brasil desde o período setecentista provocando mudanças profundas em ecossistemas distintos e ameaçando a manutenção da biodiversidade pelo domínio de grandes áreas. Este trabalho objetivou apontar ocorrência e usos de espécies exóticas em comunidades rurais da Chapada do Araripe, sul do Ceará, enfocando o comparativo entre o conhecimento popular e os resultados de pesquisa de campo e herbários virtuais. Foram realizadas 12 expedições às comunidades rurais de Cruzeiro, Baixa do Maracujá, Santo Antônio (em Crato), Macaúba e Bela Vista (Barbalha), onde coleta de material botânico e entrevistas por questionários semiestruturados foram realizadas. Na pesquisa em bases de dados e in loco apontou-se 56 espécies distribuídas em 32 famílias, sendo Poaceae (nove ssp. - 5,04%) a mais representativa. O estudo etnodirigido apontou ocorrência de 181 espécies e 155 gêneros distribuídos em 69 famílias, com prevalência de Araceae (10 spp. – 18,1%) e Lamiaceae (nove spp. – 16,29%). Aloe L. e Echeveria DC. foram os gêneros de maior destaque (quatro spp.) e Persea americana Mill. (Lauraceae) e Musa sp. L. (Musaceae), as espécies de maior IVI: 0,32. Azadirachta indica A. Juss. (Meliaceae) foi a arbórea prevalecente em todos os meios de investigação, apontando a necessidade de controle. Com isto, contribui-se para que ações e estratégias de contenção e erradicação de espécies prejudiciais neste ambiente sejam elaboradas, auxiliando tomadas de decisões. Este é o primeiro trabalho a apresentar listagem de plantas exóticas na Chapada do Araripe e propõe medidas de manejo voltadas à mitigação de eventuais impactos causados por alguns representantes.Palavras-chave: Invasão biológica, Plantas exóticas, Chapada do Araripe, Etnobotânica.Exotic plants in Chapada do Araripe (Northeast Brazil): occurrence and uses A B S T R A C TExotic plants occur in Brazil since the 18th century, causing profound changes in different ecosystems and threatening the maintenance of biodiversity by dominating large areas. This study aimed to point out the occurrence and uses of exotic species in rural communities in Chapada do Araripe, southern Ceará, focusing on the comparison between popular knowledge and the results of field research and virtual herbaria. Twelve expeditions were carried out in rural communities of: Cruzeiro, Baixa do Maracujá, Santo Antônio (in Crato), Macaúba and Bela Vista (Barbalha), where collection of botanical material and interviews by semi-structured questionarys were carried out. In the data base research, 56 regions in 3 families are based, being Poaceae - 5.04%) the most representative. The ethno-directed study pointed the occurrence of 181 species and 155 genera distributed in 69 families with prevalence of Araceae spp. – 18.1%) and Lamiaceae (no10 spp. – 16.29%). Aloe L. and Echeveria DC. were the most prominent genera (four spp.) and Persea americana Mill. (Lauraceae) and Musa sp. L. (Musaceae), the species with the highest IVI: 0.32. Azadirachta indica A. Juss. (Meliaceae) was the prevailing tree in all means of investigation, in view of the need for control. With this, this study contributes so that actions and strategies to contain and eradicate harmful species in this environment are developed, helping in decision making. This is the first to feature the listing exotic plants in Chapada do Araripe and and proposes management measures aimed at mitigating possible impacts caused by some representatives.Keywords: Biological invasion, Exotic plants, Chapada do Araripe, Ethnobotany.
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Singh, Apurwa, and Sanyogita Shahi. "Comparative Review of Indian Medicinal Plants Containing Allantoin." Journal of Neonatal Surgery 14, no. 8 (2025): 320–32. https://doi.org/10.63682/jns.v14i8.7218.

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Allantoin, a naturally occurring nitrogenous heterocyclic compound with the empirical formula C₄H₆N₄O₃, exhibits significant dermatological and regenerative properties, including potent wound healing, tissue regeneration, anti-inflammatory, and emollient effects. While primarily recognized for its abundance in Symphytum officinale (comfrey), recent phytochemical investigations have revealed its presence or substantiated allantoin-like bioactivity in numerous indigenous Indian medicinal plants. These botanicals, deeply integrated into traditional Indian medicine systems such as Ayurveda, Unani, and Siddha, represent promising avenues for advanced pharmacological exploration. This review provides a comparative analysis of six key Indian medicinal plants—Pisonia grandis, Plantago major, Symphytum officinale, Aloe vera, Beta vulgaris (beetroot), and Musa spp. (banana)—known to contain allantoin or elicit analogous therapeutic responses. For each species, traditional ethnomedicinal applications, established phytochemical profiles, and documented health benefits are critically examined, with particular emphasis on evidence of allantoin identification or inferred contribution to observed bioactivity. Direct chemical profiling methods, such as RP-HPLC, have confirmed allantoin in Pisonia grandis, Plantago major, and Symphytum officinale. While direct quantification in Aloe vera, Beta vulgaris, and Musa spp. remains less consistently reported in peer-reviewed literature, their established therapeutic actions in wound care and inflammation management strongly suggest the involvement of allantoin or functionally similar compounds. The review further elucidates allantoin’s molecular mechanisms, including its role in stimulating cellular proliferation, accelerating extracellular matrix remodelling, and modulating inflammatory cascades, properties central to its utility in dermatological and advanced wound-care formulations. The efficacy of these plants in traditional Indian medicine is supported by extensive ethnobotanical records and a growing body of modern pharmacological studies. However, a significant gap persists in the standardized phytochemical evaluation and quantitative determination of allantoin across a broader spectrum of Indian medicinal herbs. Consequently, this review underscores the imperative for rigorous biochemical and pharmacological investigations to confirm allantoin's presence, assess its bioavailability, and systematically explore its full therapeutic potential for contemporary clinical applications.
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Yörük, Nuray Gamze. "Analysis of biological activities of Aloe vera gel and extract used as the potential use in natural food additives." Revista Científica de la Facultad de Ciencias Veterinarias XXXIV, no. 3 (2024): 1–9. http://dx.doi.org/10.52973/rcfcv-e34453.

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El propósito de este estudio es evaluar las propiedades antimicrobianas del gel de Aloe vera (AVG) y el extracto de Aloe vera (AVE). En el contexto de la seguridad alimentaria, el enfoque principal ha sido el uso potencial de estos productos naturales como conservantes de alimentos y sus efectos a nivel microbiano. Como parte del estudio, se prepararon AVG y AVE en diferentes concentraciones (1, 2, 3, 4 y 5% p/v). Los microorganismos utilizados en las pruebas incluyeron Salmonella spp., Staphylococcus aureus, Escherichia coli, Bacillus subtilis subsp. spizizenii, Candida albicans y Aspergillus niger. Los análisis microbiológicos se realizaron de acuerdo con las normas ISO y las cargas microbianas se evaluaron en diferentes diluciones. El análisis estadístico de los datos se realizó mediante la prueba de rangos con signos de Wilcoxon, la prueba no paramétrica de Friedman y el ANOVA bidireccional. Se descubrió que ambas formas de AVG y AVE eran efectivas contra ciertas bacterias y hongos probados. Específicamente, la forma de gel de AVG mostró efectividad contra B. subtilis y E. coli, mientras que la forma de extracto fue ineficaz contra estos microorganismos. Los análisis estadísticos indicaron que el tiempo es un factor importante en la eficacia antimicrobiana de AVG y AVE. El estudio presentó hallazgos que respaldan el uso potencial de AVG y AVE como conservantes de alimentos.
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Domenico Prisa and Marco Gobbino. "Biological treatments for quality improvement and production of Aloe vera gel." GSC Advanced Research and Reviews 9, no. 1 (2021): 054–63. http://dx.doi.org/10.30574/gscarr.2021.9.1.0237.

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Research goal: The aim of this work was to develop a sustainable and innovative organic cultivation protocol, usable by local Italian companies, based on the use of microbial biostimulants (beneficial bacteria and fungi, arbuscular mycorrhizae and algae) able to improve the growth and quality production of the medicinal gel of Aloe vera. Materials and Methods: The experiments, started in December 2020, were conducted in the greenhouses of CREA-OF in Pescia (Pt), Tuscany, Italy (43°54′N 10°41′E) on Aloe vera (4 year old plants). The experimental groups were: i) group control, irrigated with water and substrate previously fertilized; ii) group with Effective microorganisms irrigated with water and substrate previously fertilized; iii) group with Trichoderma spp. irrigated with water and substrate previously fertilized; iv) group with arbuscular mycorrhizae irrigated with water and substrate previously fertilized; v) group with Ascophyllum nodosum irrigated with water and substrate previously fertilized. Results and Discussion: The experiment showed a significant improvement in agronomic parameters and physical, chemical and microbiological characteristics analysed on plants treated with microbial and algae-based biofertilizers. In particular, there was a significant improvement in the number of leaves per plant, new shoots, fresh vegetative weight, root and gel weight and the inflorescences number. On the leaves of the treated theses, there was a significant increase in leaf length and width and an improvement in gel pureness (optical density). There was also an increase in the number of microorganisms in the treated substrates and a lowering of the pH of the growing medium. The test also showed a lowering of the pH of the gel and a significant increase in soluble solids, sugars and fiber content in the theses inoculated with Effective microorganisms and a significant increase in fructose, glucose, proline and aloin. Conclusions: The trial confirms the significant results already obtained in other trials on vegetable, ornamental and Aloe plants by applying biofertilizing microorganisms and algae. The aim of this work was to develop an organic cultivation protocol based on microbial and algae treatments that can be used to improve the quality of Aloe vera plants. This protocol can be applied in general by those companies that are dedicated to the production of ornamental and fruit cacti and succulents and want to reduce or even eliminate the use of plant protection products
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de Souza Collares Maia Castelo-Branco, Débora, Géssica dos Santos Araújo, Xhaulla Maria Quariguasi Cunha Fonseca, et al. "Anthraquinones from Aloe spp. inhibit Cryptococcus neoformans sensu stricto: effects against growing and mature biofilms." Biofouling 37, no. 8 (2021): 809–17. http://dx.doi.org/10.1080/08927014.2021.1958793.

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Patil, Aarti, and Sury Pratap Singh. "Study on the Therapeutic Properties of Herbs and Their Utilization in the Development of Value-Added Products: A Review." Journal of Scientific Research and Reports 29, no. 7 (2023): 71–83. http://dx.doi.org/10.9734/jsrr/2023/v29i71761.

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India has the largest population of cattle in the world and also ranks first in consumption considering it as having a huge demand for dairy and value-added dairy products. A wide range of dairy products is already available in the market like butter, cheese, labneh, ice cream, buttermilk, custard, etc. Yogurt is one of the oldest consumed dairy products with several benefits as it contains various microorganisms such as Lactic acid bacteria, Lactobacillus spp. and Streptococcus spp. which ferment the product and it helps in improving the nutritional value of the product. Yogurt contains a rich source of B vitamins, lactose, proteins, and minerals. To enhance its nutritional value herbs and fruits can be added to it. Herbs are a type of plant whose leaves and seeds have a wide range of use in medicines, adding flavor, cooking, etc. Herbs are anti-inflammatory, have antioxidants, boost the immune system, and have several other health benefits. Different types of herbs and their health benefits were studied such as Ashwagandha, Arjuna, Cinnamon, Sage, Aloe vera, Tulsi, and Peppermint. Fruits are added to dairy products to enhance their flavor and nutritional value. Fruits are a good source of vitamins and minerals. In this review paper, we discuss the nutritional prospects of yogurt supplemented with herbs.
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Pranita, A. Gulhane* Namrata G. Shukla and Ashok V. Gomashe. "NATURAL PLANT EXTRACTS: A NOVEL THERAPY FOR SHELF LIFE EXTENSION AND QUALITY RETENTION OF FRUITS." INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & RESEARCH TECHNOLOGY 7, no. 1 (2018): 344–49. https://doi.org/10.5281/zenodo.1147482.

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Fruits provide adequate supplies of vitamins, minerals and fibers to human health. Fruits harvested for human consumption are susceptible for microbial spoilage. Post-harvest loss of fruits poses a serious issue across the globe. Therefore, there is an urgent need to have a natural preservative that will improve the shelf life and quality of fresh fruits. Hence the present investigation was aimed to evaluate the efficacy of natural plant extracts (edible coating solution) like Neem oil, Guar gum, Aloe vera gel and Marigold extract as potential fruit preservatives against 5 different types of fruits such as Apple, Banana, Chikoo, Papaya and Tomato. It was found that except Apple and Chikoo other selected fruits lost their weight even after treatment with the edible coating solution. The study revealed that two types of organisms were found on fruit surface such as <em>Staphylococcus</em> spp. and <em>Pseudomonas</em> spp. Skin colour analysis showed that Apple was found to be excellent in skin colour while Tomato was good, Papaya and Chikoo were slightly dull whereas banana was &lt;50% brownish in colour. Pulp colour analysis showed that Apple and Tomato were 100% Good, Papaya 75% Good, Chikoo 50% Good while Banana 25% Good.
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Domenico, Prisa, and Gobbino Marco. "Biological treatments for quality improvement and production of Aloe vera gel." GSC Advanced Research and Reviews 9, no. 1 (2021): 054–63. https://doi.org/10.5281/zenodo.5600503.

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<strong>Research goal:</strong>&nbsp;The aim of this work was to develop a sustainable and innovative organic cultivation protocol, usable by local Italian companies, based on the use of microbial biostimulants (beneficial bacteria and fungi, arbuscular mycorrhizae and algae) able to improve the growth and quality production of the medicinal gel of&nbsp;<em>Aloe vera</em>. <strong>Materials and Methods:&nbsp;</strong>The experiments, started in December 2020, were conducted in the greenhouses of CREA-OF in Pescia (Pt), Tuscany, Italy (43&deg;54&prime;N 10&deg;41&prime;E) on&nbsp;<em>Aloe vera</em>&nbsp;(4 year old plants). The experimental groups were: i) group control, irrigated with water and substrate previously fertilized; ii) group with Effective microorganisms irrigated with water and substrate previously fertilized; iii) group with&nbsp;<em>Trichoderma spp.</em>&nbsp;irrigated with water and substrate previously fertilized; iv) group with arbuscular mycorrhizae irrigated with water and substrate previously fertilized; v) group with&nbsp;<em>Ascophyllum nodosum</em>&nbsp;irrigated with water and substrate previously fertilized. <strong>Results and Discussion:</strong>&nbsp;The experiment showed a significant improvement in agronomic parameters and physical, chemical and microbiological characteristics analysed on plants treated with microbial and algae-based biofertilizers. In particular, there was a significant improvement in the number of leaves per plant, new shoots, fresh vegetative weight, root and gel weight and the inflorescences number. On the leaves of the treated theses, there was a significant increase in leaf length and width and an improvement in gel pureness (optical density). There was also an increase in the number of microorganisms in the treated substrates and a lowering of the pH of the growing medium. The test also showed a lowering of the pH of the gel and a significant increase in soluble solids, sugars and fiber content in the theses inoculated with Effective microorganisms and a significant increase in fructose, glucose, proline and aloin. <strong>Conclusions:</strong>&nbsp;The trial confirms the significant results already obtained in other trials on vegetable, ornamental and Aloe plants by applying biofertilizing microorganisms and algae. The aim of this work was to develop an organic cultivation protocol based on microbial and algae treatments that can be used to improve the quality of&nbsp;<em>Aloe vera</em>&nbsp;plants. This protocol can be applied in general by those companies that are dedicated to the production of ornamental and fruit cacti and succulents and want to reduce or even eliminate the use of plant protection products
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Zapata, P. J., F. Guillén, S. Castillo, D. Martínez-Romero, D. Valero, and M. Serrano. "PREHARVEST APPLICATION OF ALOE VERA GEL EXHIBITS ANTIMICROBIAL ACTIVITY BY REDUCING YEAST, MOULD, AND AEROBIC COUNTS AT HARVEST IN SEVERAL PRUNUS SPP." Acta Horticulturae, no. 1012 (November 2013): 121–26. http://dx.doi.org/10.17660/actahortic.2013.1012.9.

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Cortez, Ramón A., Olga P. Pineda, Mireya Zelaya, Francia Beltrán, Elia Sarmiento, and Iris Rodríguez. "Conocimiento local y uso de plantas medicinales en tres comunidades de San Ignacio y Cedros, Francisco Morazán, Honduras: algunas implicaciones bioculturales." Portal de la Ciencia, no. 20 (June 19, 2025): 105–42. https://doi.org/10.5377/pc.v1i20.20418.

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El estudio de las plantas medicinales es clave para preservar el conocimiento tradicional sobre los recursos naturales y desarrollar nuevas aplicaciones terapéuticas. Ante la falta de investigaciones previas, esta primera exploración documenta el uso tradicional de estas plantas en tres comunidades de San Ignacio y Cedros, ubicadas en los alrededores del área de manejo forestal Casta Rica-Sansone, en el departamento de Francisco Morazán, Honduras. Mediante entrevistas semiestructuradas, se recopilaron datos sobre especies vegetales y sus usos. A la información se le aplicaron los índices de factor de consenso de los informantes (ICF), importancia relativa (RI) y uso significativo TRAMIL, con el fin de evaluar el grado de conocimiento tradicional, la versatilidad de las plantas medicinales reportadas y su aceptación cultural. Se identificaron 106 especies pertenecientes a 53 familias botánicas, siendo Asteraceae, Rutaceae y Fabaceae las más representadas, con predominio de especies herbáceas. Se observó que las hojas son la parte más utilizada, mientras que las formas de preparación más comunes incluyen tés e infusiones. Las plantas medicinales se emplean para tratar diversas afecciones, destacando entre las más usadas la sábila (Aloe vera), el orégano (Lippia origanoides) y la hierbabuena (Mentha spp.). Los resultados indican que el sistema respiratorio obtuvo el mayor consenso entre los informantes (ICF = 0.38). La sábila (Aloe vera) fue la especie con mayor importancia relativa (RI = 2.00), debido a su amplio uso en diversas afecciones. Por su parte, el orégano presentó el mayor nivel de uso significativo TRAMIL (UST = 47.4). Además de resaltar la importancia de estas especies en la medicina tradicional, el estudio subraya la necesidad de preservar este conocimiento frente a las amenazas de la modernización y la migración. Se recomienda también implementar estrategias sostenibles para la conservación y transmisión del saber ancestral asociado al uso de plantas medicinales en estas comunidades rurales.
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Kibet Chebii, Willy, John Kaunga Muthee, and James Karatu Kiemo. "Traditional medicine trade and uses in the surveyed medicine markets of Western Kenya." African Health Sciences 22, no. 4 (2022): 695–703. http://dx.doi.org/10.4314/ahs.v22i4.76.

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Background: There exist vast traditional medicine and herbal remedies prescribed for diseases and socio-cultural ills that are sold in local medicine markets.Objectives: To assess the common traditional medicine traded in the local medicine markets and used for treating common diseases.Methods: The study was carried out in nine purposively selected medicine markets spread out in seven administrative counties of Western Kenya. Purposive sampling with elements of snow ball method was employed in the identification of willing respondents.In addition, face to face interviews were conducted with the aid of a pre-tested semi-structured questionnaire that sought to extract a targeted and expertise information from the respondents.Results: The survey recorded 45 commonly traded plant families composed of 78 genera and 87 medicinal plant species. Meliaceae, Apocynaceae and Fabaceae were leading plant families whereas Trichilia emetica, Azadirachta indica, Dregea schimperi and Aloe spp. were commonly traded.Conclusion: Traditional medicine traded in the local medicine markets continue to play a significant role in the treatment of common diseases. Frequently traded medicinal plant species should be prioritized for conservation.Keywords: Traditional Medicine; Common disease treated; Medicine markets.
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Bochner, R., J. T. Fiszon, M. A. Assis, and K. E. S. Avelar. "Problemas associados ao uso de plantas medicinais comercializadas no Mercadão de Madureira, município do Rio de Janeiro, Brasil." Revista Brasileira de Plantas Medicinais 14, no. 3 (2012): 537–47. http://dx.doi.org/10.1590/s1516-05722012000300017.

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O uso de plantas medicinais pela população brasileira é prática tradicional, sendo muitas vezes o único recurso utilizado na atenção básica de saúde. O uso terapêutico dessas plantas envolve várias etapas da cadeia produtiva, sendo a procedência, coleta, secagem, armazenamento, comércio, modo de preparo pelo usuário e uso. O objetivo desse trabalho documental, de caráter exploratório, foi levantar a produção científica existente sobre os problemas associados a cada uma dessas etapas e discutir as questões relacionadas à carência de estudos para comprovar a eficácia farmacológica e a ausência de riscos toxicológicos, bem como a prática de autodiagnóstico. As vinte plantas mais comercializadas em grande mercado do município do Rio de Janeiro em agosto de 2007 serviram de base para o levantamento documental do presente estudo. Dessas, seis apresentaram propriedades tóxicas comprovadas dependendo do preparo e uso, a arnica (Solidago chilensis Meyen), aroeira (Shinus terebinthifolius Raddi.), arruda (Ruta graveolens L.), babosa (Aloe vera L.), confrei (Symphytum officinale L.) e poejo (Mentha pulegium Lam. &amp; DC.). A Agência Nacional de Vigilância Sanitária aponta contra indicações para boldo-do-Chile (Peumus boldus Molina), chapéu-de-couro (Echinodorus macrophyllus Micheli), erva-cidreira (Lippia alba N.E.Br.), erva-de-bicho (Polygonum spp.), espinheira-santa (Maytenus spp.), picão (Bidens pilosa L.), poejo (Mentha pulegium Lam.) e tanchagem (Plantago major L.). O abajerú, arnica, boldo-do-Chile, confrei, erva-de-bicho e espinheira-santa tiveram relato de problemas de identificação na coleta e comercialização frente a outras morfologicamente semelhantes. Plantas cultivadas e silvestres apresentam variabilidade de princípios ativos influenciados por fatores ambientais e genéticos, como chapéu-de-couro (Echinodorus macrophyllus Micheli), erva-cidreira (Lippia alba N.E.Br.) e erva-de-bicho (Polygonum spp.). A contaminação e o comprometimento da preservação dos princípios ativos pela secagem e armazenamento inadequados foram relatados para o guaco (Mikania glomerata Sprengel), camomila (Chamomilla recutita L.), erva-cidreira, chapéu-de-couro e boldo-do-Chile (Peumus boldus Molina). Pode-se constatar que todas as etapas da cadeia produtiva das plantas medicinais apresentam desafios para que se possa garantir identificação da espécie, disponibilidade, qualidade, segurança e eficácia de uso.
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40

Kumar, Rajiv, Bhavna Sharma, Neha R. Tomar, Partha Roy, Atul K. Gupta, and Anil Kumar. "In Vivo Evalution of Hypoglycemic Activity of Aloe spp. and Identification of Its Mode of Action on GLUT-4 Gene Expression In Vitro." Applied Biochemistry and Biotechnology 164, no. 8 (2011): 1246–56. http://dx.doi.org/10.1007/s12010-011-9210-6.

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41

Meena, P. N., A. N. Tripathi, B. S. Gotyal, and S. Satpathy. "Bio-efficacy of phytoextracts and oil cakes on Macrophomina phaseolina (Tassi) causing stem rot disease of jute, Corchorus spp." Journal of Applied and Natural Science 6, no. 2 (2014): 530–33. http://dx.doi.org/10.31018/jans.v6i2.494.

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In the present study efforts were made to explore the efficacy of various plant extracts and oil cakes against Macrophomina phaseolina. The efficacy of eight different plant species, Zingiber officianale, Aloe indica, Lawsonia inermis, Chenopodium album, Allium cepa, Piper betel, Murraya koenigii, Parthenium hysterophorus aqueous extracts including oil cakes of mustard and neem were evaluated by using of poisoned food technique in vitro for their inhibitory effect on mycelial growth of M. phaseolina causing stem rot of jute (Corchorus olitorius and C. capsularis). The rhizome extract of Z. officinale produced maximum growth inhibition (74.59%) of the pathogen followed by leaf extracts of A. indica (63.57%), and leaf extract of L. inermis (60.17%) at the concentration of 10%. The maximum mycelial growth inhibition (52.40%) was recorded with neem cake (Azadirachta indica) at the concentrations of 20% followed by 42.61% and 29.60% with concentration of 15% and 10%, respectively. However, maximum mycelial growth inhibition (19.42%) was recorded with mustard cake (Brassica juncea) at the concentration of 20% followed by 16.64% and 12.20% at the concentration of 15% and 10% respectively. In general mycelial growth inhibition was dose dependent and it was maximum in case of neem cake than mustard cake. The present study revealed that, these plant extracts and oilcake extracts could be exploited for the possible control of deadly pathogen M. phaseolina. Accordingly, this is an important proactive measure in preventing the spread of the stem rot disease through a more ecofriendly approach.
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da Costa Ferreira, Ezequiel, Maria da Glória Vieira Anselmo, Natan Medeiros Guerra, et al. "Local Knowledge and Use of Medicinal Plants in a Rural Community in the Agreste of Paraíba, Northeast Brazil." Evidence-Based Complementary and Alternative Medicine 2021 (December 29, 2021): 1–16. http://dx.doi.org/10.1155/2021/9944357.

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The use of medicinal plants is an important source of therapeutic resources in rural communities and the wide versatility of some species may attract interest for prospecting studies. The aim of this study was to record and analyze local knowledge and the use of medicinal plants in the rural community of Malícia, municipality of Araçagi, Paraíba State, Northeastern Brazil, applying quantitative methods to calculate the Relative Importance (RI) and the Informant Consensus Factor (ICF). Semistructured interviews were conducted with 46 heads of households. The interviews addressed questions about the used parts of the plants, therapeutic indications, and form of use. Therapeutic indications were classified into categories of body systems. The Relative Importance Index (RI) was calculated to verify the species versatility, and the Informant Consensus Factor (ICF) was calculated to verify the consensus of use among informants regarding the body systems. A total of 111 plant species were recorded, inside 101 genera and 47 families. Fabaceae (16 spp.), Lamiaceae, and Myrtaceae (each one with 7 spp.) were the most representative families. Mentha arvensis, Aloe vera, and Myracrodruon urundeuva had the highest RI. A high consensus of use was observed among the informants for neoplasms, nervous system diseases, and infectious and parasitic diseases. Leaves were the part most cited for medicinal use. Regarding the method of preparation, the decoction and the oral administration route stood out. Neoplasms and respiratory system diseases had the highest ICF values. The results indicate a diversified knowledge of the local pharmacopeia and the need for in-depth studies to corroborate the effectiveness of medicinal plants and to understand the dynamics of local knowledge.
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Hussain, Shahid, Muhammad Naeem Aslam, Basharat Mehmood, et al. "Antimycotic Properties of Potentials Botanical Crude Extracts and Bio-Control Agent against Fusarium Wilt of Chili caused by Fusarium oxysporum f.sp. capsici." Journal of Agriculture and Veterinary Science 2, no. 3 (2023): 213–21. https://doi.org/10.55627/agrivet.002.03.0368.

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Fusarium wilt is a devastating disease of Chili in Pakistan and its management is very difficult. Therefore the studies were conducted in in-vitro conditions. Mmycelium appeared were yellow, reddish-brown or blue-black in color. Macro conidia short, straight, or 40-75 x 25.5-5 micron and long 5-8 septate. Micro conidia consist of 1-3 septate, with a short beak and 22-48 x 3.4 microns. The results showed that the disease is present in high frequency throughout the districts surveyed. The maximum disease incidence was recorded in Hyderabad (55%) whereas; the incidence of the disease from the Tando Allahyar district was recorded up to (35%). The used botanical extracts showed high variation in reducing the colony growth of the fungus. All the botanical extracts significantly reduced the mycelial growth of Fusarium oxysporum. Eucalyptus leaves was found most effective in reducing the colony growth of the fungus at their highest dose (6.33 mm), Aloe suppress the fungal mycelial growth (21.00 mm). Whereas the Mari gold reduce the fungal growth (25.33 mm) and Mint leaves (26.33 mm). All the botanical extracts at their respective doses significantly retarded the growth of fungus as compared to control (82.00 mm). Trichoderma spp. as bio control agent was tested in-vitro condition against Fusarium oxysporum and significantly reduced the mycelial growth of Fusarium oxysporum. Trichoderma spp. reduces the activity of the Fusarium oxysporum (10.00 mm) as compared to control (82.00 mm). Based on the in-vitro result Eucalyptus leaves extract can be effectively used for field experiment. These studies will be helpful for researchers and growers.
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Nikita, Pol Akanksha Raut Chaitali Dhale*. "USE OF ANTI INFLAMMATORY DRUGS IN ALOE VERA GEL BASE FORMULATION." International Journal in Pharmaceutical Sciences 1, no. 12 (2023): 806–13. https://doi.org/10.5281/zenodo.10431997.

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For thousands of years, people have utilized Aleo vera, a cactus-like plant in the Asphodelaceae (Liliaceae) family , for traditional medical treatments. Because of the bitter juice present in the &nbsp;leaves, Aloe vera gets its name from the Arabic word &ldquo;Alloeh,&rdquo;which means &ldquo;shining bitter substance,&rdquo; and the Latin word &ldquo;vera&rdquo; which means &ldquo;True&rdquo;. Aloes come in more than 300 species, the majority of which are indigenous to south Africa, Madagascar, and Arabia. There is a long history of using herbal therapy to treat a wide range of infectious disorders in &nbsp;many regions of the world. One of the key ingredients in traditional medicine is Aloe vera. Aloe vera is a botanical remedy that has been used for a very long time by many different cultures. The succulent plant grows in arid and subtropical regions is most well-known for two different preparations: the thick sap of the leaves, which turns yellow-brown and has potent &nbsp;laxative properties that warn against using it, and the clear, mucilaginous gel is widely used to treat minor burns, especially sunburns. &nbsp; &nbsp;
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Alzamilie, Bashar. "The evaluation of the Theraputic Effect of Aqueous Extract of Aloe Vera on Entamoeba histolytica in Vivo." Wasit Journal for Pure sciences 3, no. 3 (2024): 329–37. http://dx.doi.org/10.31185/wjps.524.

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Ameobiasis caused by Entameoba spp. It is a zoonotic disease that is the most prevalent. Thus, the study was conducted to evaluate the anti-ameobiasis efficacy of aqueous Aloe vera extracts in comparison with metronidazole in laboratory mice. Stool samples were collected from patients attending in Al-karamah teching Hospital suffering from diarrhea from November 1, 2022 to February 29, 2023, and 15samples were examined for both sexes microscopic by using the lugols iodine Stain to detect infected the parasite's cysts , Isolation and purification by flotation with normal solution and preserved in potassium dichromate for the purpose of using it in causing infection in laboratory mice. The experimental study was conducted on groups of 35 mice by oral administration of parasite cysts within the range of 95 cyst / ml except for the negative control group that was drenched with physiological saline. The feces of mice inoculated with cysts of parasites were microscopically examined using the modified lugols iodine Stain, After the mice were divided into seven groups with the uninfected and untreated group kept as a healthy negative control. The first group which included 21 mice was treated after it was divided into three subgroups A, B, C for each secondary group 7 mice they were treated with aqueous extract of A.vera at different concentrations 50, 100, 150 mg/ml on the respectively, while the second group which included 21 mice on three groups A, B, and C was treated with aqueous extract of A.vera at the previous concentrations for three consecutive days for each concentration. The third group was treated with metronidazole at a concentration of mg/ ml, and the positive control group remained infected with the parasite and was not treated. After treatment a microscopic examination was performed by evaluating the excretion average of parasite cysts using a hematocytometer slide. There was a decrease in the shedding of fecal cysts in the groups treated with aqueous extract at different concentrations, reaching a complete stop when treating with the highest concentrations at the end of the treatment period. Where, the average of shedding of fecal parasite cysts of groups of mice at concentrations 50, 100, 150 mg/ml reached 18.20, 0.200, 0 cyst/ml respectively. while the avrage of shedding of cysts in the group treated with metronidazole reached 60.20 cyst/ml in comparison with the infected positive control group in which the number of cysts continued to increase to 14.863 cyst/ml at the end of the treatment period. The results of the therapeutic efficacy of A.vera extract showed percentages of 82%, 90%, 100% for the aqueous extract at concentrations 50, 100, 150 mg/ml, respectively, while the therapeutic efficacy of metranidazol reached 84% at the end of the treatment period
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46

Said, Mohamed, and Kalista Peter. "The Use of Medicinal Plants and Its Implication on Plants Conservation: The Case of West Usambara, Tanzania." JOURNAL OF THE GEOGRAPHICAL ASSOCIATION OF TANZANIA 42, no. 1 (2022): 1–21. http://dx.doi.org/10.56279/jgat.v42i1.214.

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In recent decades, medicinal plants have been overused. The failure of some modern medicines, an increase in degenerative diseases and the trading of medicinal plants are among the factors that have triggered such overutilization. This study was carried out in West Usambara Mountains, in Tanzania, to investigate the effects of medicinal plant harvesting on plants conservation. We collected ethnobotanical data from 160 respondents. Interviews and field observation were the main data collection methods. SPSS Version 25 was used to analyse the collected data to understand the knowledge on the parts of medicinal plant used, the preparation of medicines from plants, amount harvested, and the effects of harvested herbs on plants conservation. Information obtained from key informants was analysed through thematic analysis. The study revealed that some medicinal plant species such as Omphalogonus calophyllus and Aloe spp. were being unsustainably harvested. Furthermore, the change from cultural ways of using medicinal plants to commercial purposes was found to be threatening plant species in the area. The study concludes that West Usambara is a rich region of diverse medicinal plants and traditional healthcare knowledge. However, the change from the culture of using medicinal plants for domestic use only to commercial use is threatening the existence of medicinal plants. Hence, it signals the need for serious efforts to be made to create public awareness; initiate and establish laws so that appropriate measures are taken to conserve medicinal plants in the fragile natural ecosystem of the West Usambara Mountains.
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47

Alasbahi, Rawiya H., and Maria J. Groot. "Ethnoveterinary Uses of Certain Yemeni Plants: A Review of the Scientific Evidence." Planta Medica 88, no. 03/04 (2021): 237–53. http://dx.doi.org/10.1055/a-1612-4556.

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AbstractLivestock is an important and integral component of agriculture production in Yemen and contributes 28% of the total agricultural production income. Research in the field of Yemeni ethnoveterinary medicine is limited to a few studies. Therefore, our work aims to substantiate scientifically the ethnoveterinary use of some documented plant species based on a literature review of their bioactivities and toxicological properties. Searching the scientific literature has revealed various pharmacological activities that may support the claimed healing activities of 11 out of 14 plant species for some of their ethnoveterinary utilization. This comprises the use of Aloe spp. latex for constipation, worms, boils, and wounds; Boswellia sacra underbark for wounds and its oleo-gum resin for mastitis; Soqotraen Boswellia species as an insect repellent; Cissus rotundifolia for stomach pain; Cyphostemma digitatum as an appetite stimulant; Psiadia punctulate for bone fracture; Pulicaria undulata as an insect repellent; combinations of Aristolochia bracteolate with Sorghum bicolor grains for bloating; Rumex nervosus and salt for eye pimples; and Trigonella foenum-graecum seeds with Hordeum vulgare grains for constipation. Some plants were found to demonstrate various toxic effects in in vivo and in vitro experimental studies. The local administration of Calotropis procera latex was also reported to induce an intense inflammatory response. It can be concluded that our work has provided valuable scientific information on the biological and toxic activities of some Yemeni ethnoveterinary remedies that could be utilized for the benefit of farmers to ration the use of these remedies and avoiding their toxicity.
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48

Ukpo, G., T. Ehianeta, A. Adegoke, O. Salako, and G. Mbaka. "Histopathological effects of Averon®, an indigenous herbal formulation, on Cyclophosphamide - induced immunosuppressed male rats." Journal of Morphological Sciences 32, no. 04 (2015): 236–44. http://dx.doi.org/10.4322/jms.069014.

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Abstract Introduction: The study investigated the effect of an acclaimed immunoboosting herbal formulation, Averon®, which contains Aloe spp on some basal physiological and pathophysiological profiles in immunomodulated male rats. Materials and Methods: Six groups of male rats were used for the study: control group received water and pelletized food ad libitum, Negative control Cyclophosphamide-treated group (30mg/kg i.p), two groups pre-treated with Cyclophosphamide (30mg/kg i.p) and followed by oral 200mg/kg and 400 mg/kg Averon® respectively, two groups orally pre-treated with 200mg/kg and 400 mg/kg Averon® respectively and followed by Cyclophosphamide (30mg/kg i.p) on the last three days. The experimental design was characterized by observations for behavioral changes in the rats, changes in body weight, food consumption, water intake and gross histopathological changes after sacriice. Results: The results revealed the adverse effects in the cyclophosphamide pre-treated groups in the behavioral pattern, significant decrease in body weights at several p-values, significant decrease in food intake (p&lt; 0.05), significant drop in water consumption and toxicological effects on the studied organs. The reverse was true for the Averon®-pretreated groups: significant increase in body weights, food intake and water consumption. The adverse effect of cyclophosphamide was most pronounced on the lungs with little or no amelioration of the adverse effects on the pulmonary milieu. However, there was remarkable recovery on the livers, kidneys and the hearts on treatment with Averon®, particularly at the higher doses. Conclusion: Averon® showed tissue ameliorating potential except on the lungs, hence the need for therapeutic monitoring when administered to immunosuppressed subjects.
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MAHANTI, Achintya, Siddhartha Narayan JOARDAR, Samiran BANDYOPADHYAY, et al. "RAW BOVINE MILK AS A RESERVOIR OF MULTI-DRUG RESISTANT, BETA-LACTAMASE-PRODUCING Klebsiella." Journal of Applied Life Sciences and Environment 57, no. 1(197)2024 (2024): 19–36. http://dx.doi.org/10.46909/alse-571122.

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The transmission of zoonotic bacteria through consumption of raw milk is complicated by the dissemination of antimicrobial-resistant bacteria. The present study was conducted to detect the occurrence of antimicrobial-resistant bacteria (ESBL-/AmpC-producing Klebsiella spp.) in cow’s milk originating from healthy or infected (mastitis) cattle in India. In total, 450 milk samples were collected from apparently healthy cattle and cattle suffering from clinical or sub-clinical mastitis. Out of 455 Klebsiella spp., 67 (14.73%) isolates were found to be ESBL producers in the double-disc diffusion test. The occurrence of ESBL-producing Klebsiella spp. was significantly (p &lt; 0.05) higher in milk samples collected from cattle suffering with mastitis than in healthy cattle. Among the ESBL-producing Klebsiella spp., 56 (83.6%) isolates were also detected that produced AmpC β-lactamases. All the ESBL and AmpC-producing Klebsiella spp. possessed blaCTX-M (100%) and blaAmpC (100%), respectively. The present study revealed a higher occurrence of class 1 integron in ESBL-producing Klebsiella spp. isolates. All ESBL-producing- Klebsiella spp. isolates were multi-drug resistant. The ciprofloxacin- and/or levofloxacin-resistant Klebsiella spp. isolates possessed the quinolone resistance gene (qnrS). The co-trimoxazole-resistant isolates possessed the sul1 and sul2 genes. Phylogenetic analysis of the studied isolates revealed that strains isolated from the same location had a clonal relationship. The study increases consumer awareness of the need to avoid raw milk consumption to prevent the spread of antimicrobial resistance in the community.
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Azahra, Safira, Nita Parisa, Fatmawati Fatmawati, Ella Amalia, and Venny Larasati. "Antibacterial Efficacy of Aloe vera Sap Against Staphylococcus aureus and Escherichia coli." Bioscientia Medicina : Journal of Biomedicine and Translational Research 3, no. 2 (2019): 29–37. http://dx.doi.org/10.32539/bsm.v3i2.87.

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Abstract&#x0D; Background&#x0D; Aloe vera is a plant that has been used as an alternative drug. This plant contains various compounds, like anthraquinone, saponin, flavonoid, alkaloid, and tannin that has an antibacterial effect against Staphylococcus aureus and Escherichia coli. Both of it were responsible for the infection incident. This study aims to determine the efficacy of Aloe vera sap as an antibacterial against Staphylococcus aureus and Escherichia coli.&#x0D; Methods&#x0D; An experimental study, in vitro using post-test only control group design, has been done at laboratory of Medical Faculty of Sriwijaya University, by examining the antibacterial activity of Aloe vera sap in five different concentration (5%, 10%, 20%, 40%, dan 80%) using well diffusion and solid dillusion method to determine the minimum bactericidal concentration (MBC). And then continued with the phytocemical screening to determine the compound inside the Aloe vera sap.&#x0D; Results&#x0D; Aloe vera sap were able to kill Staphylococcus aureus at 5% and Eshcerichia coli at 80%. Compatibility test showed that Aloe vera sap with concentration of 10%, 20%, 40%, and 80% are compatible with amoxicillin, therefore 80% is compatible with cefotaxime. This ability due to the compound that it contains, which is alkaloid, flavonoid, tannin, quinone, and saponin.&#x0D; Conclusion&#x0D; Aloe vera sap is effective as an antibacterial against Staphylococcus aureus and Escherichia coli.&#x0D; &#x0D; Keyword: Aloe vera sap, antibacterial, efficacy, Staphylococcus aureus, Escherichia coli.&#x0D;
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