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Journal articles on the topic 'Aloin-B'

Author: Grafiati

Published: 3 June 2025

Last updated: 20 July 2025

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1

SARAVANAN, RAJU, NARENDRA ATMARAM GAJBHIYE, JAYANTI S. MAKASANA, and VELUMANI RAVI. "Barbaloin content of aloe (Aloe barbadensis) leaf exudates as affected by different drying techniques." Indian Journal of Agricultural Sciences 85, no. 7 (2015): 936–39. http://dx.doi.org/10.56093/ijas.v85i7.50126.

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Aloe (Aloe barbadensis Mill.) is commercially cultivated for its transparent leaf gel and leaf exudates. The leaf exudates collected from epidermal layer contain anthraquinone glycosides (aloins) mainly barbaloin (aloin A) and isobarbaloin (aloin B). Aloin A is used as a raw material for the production of diacylrhein, a potent drug prescribed for rheumatoid arthritis. Conventional drying of leaf exudates in open sun causes changes in physicochemical properties and altered aloin A and B composition. Various drying techniques, viz. oven drying, freeze drying, shade drying and open sun drying wer

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Oumer, Anwar, Daniel Bisrat, Avijit Mazumder, and Kaleab Asres. "A New Antimicrobial Anthrone from the Leaf Latex of Aloe trichosantha." Natural Product Communications 9, no. 7 (2014): 1934578X1400900. http://dx.doi.org/10.1177/1934578x1400900717.

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Phytochemical investigation of the leaf latex of Aloe trichosantha by preparative TLC gave two closely related anthrones, aloin A/B (1) and aloin-6'-O-acetate A/B (2). The identity of the compounds was established from HRESI-MS, 1H, 13C, DEPT, HMQC and HMBC spectral and chemical data. Whilst aloin A/B occurs in several Aloe species, aloin-6'-O-acetate A/B was isolated for the first time. The isolated compounds inhibited growth of several bacterial and fungal pathogens with minimum inhibitory concentration (MIC) from 10 to 400 μg/mL and 800 to 1000 μg/mL, respectively.

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3

Tang, Shi Rong, Shang Long Chen, Sang Sang Lu, and Xin Yang Hu. "Isolation and Purification of Aloin a and Aloin B by High-Speed Counter-Current Chromatography." Advanced Materials Research 634-638 (January 2013): 1241–46. http://dx.doi.org/10.4028/www.scientific.net/amr.634-638.1241.

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High-speed counter-current chromatography(HSCCC) was successfully used for isolation and purification of Aloin A and Aloin B from the crude methanol extract of Aloe with a two-phase solvent system composed of chloroform–methanol–n-butylalcohol-water at an optimized volume ratio of 4:3:1:2 (v/v/v/v). The lower phase was used as the mobile phase in the head to tail elution mode. The preparative HSCCC separation was performed on 180 mg of the crude extract yielding pure Aloin A(18mg) and Aloin B(16mg) at purities of 95.2% and 96.8%, respectively, as determined by high performance liquid chromatog

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4

Tsegay, Mengsteab, Yitagesu Tewabe, Daniel Bisrat, and Kaleab Asres. "In vivo anti-inflammatory activity of two anthrones from the leaf latexes of Aloe adigratana reynolds and Aloe elegans todaro." Ethiopian Pharmaceutical Journal 34, no. 1 (2019): 1–8. http://dx.doi.org/10.4314/epj.v34i1.1.

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Aloe adigratana Reynolds and Aloe elegans Todaro are traditionally used for the treatment of various illnesses, including wounds, infections and inflammation in northern Ethiopia. Despite their morphological differences, the leaf latexes of both Aloes showed the same chemical profile when analyzed by TLC. Further phytochemical investigation of these latexes by preparative thin layer chromatography (PTLC) afforded two anthrones, which were identified as aloin A/B and microdontin A/B on the basis of NMR and MS analysis. In the present study, in vivo anti-inflammatory activities of the leaf latex

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5

Yang, Sumin, Wonhwa Lee, Bong-Seon Lee, et al. "Aloin Reduces HMGB1-Mediated Septic Responses and Improves Survival in Septic Mice by Activation of the SIRT1 and PI3K/Nrf2/HO-1 Signaling Axis." American Journal of Chinese Medicine 47, no. 03 (2019): 613–33. http://dx.doi.org/10.1142/s0192415x19500320.

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High mobility group box 1 (HMGB1) is recognized as a late mediator of sepsis, and the inhibition of HMGB1 release and recovery of vascular barrier integrity have emerged as attractive therapeutic strategies for the management of sepsis. We tested the hypothesis that aloin induces sirtuin 1 (SIRT1) and heme oxygenase (HO)-1, which inhibit HMGB1 release in lipopolysaccharide (LPS)-stimulated cells, thereby inhibiting HMGB1-induced hyperpermeability and increasing the survival of septic mice. Aloin was administered after LPS or HMGB1 challenge, and the antiseptic activity of aloin was determined

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Rauwald, Hans W., Karsten Lohse, and Jan W. Bats. "Establishment of Configurations for the Two DiastereomericC-Glucosylanthrones Aloin A and Aloin B." Angewandte Chemie International Edition in English 28, no. 11 (1989): 1528–29. http://dx.doi.org/10.1002/anie.198915281.

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7

Romani, Annalisa, Pamela Vignolinia, Laura Isolani, et al. "In Vitro Radical Scavenging and Anti-Yeast Activity of Extracts from Leaves of Aloe Species Growing in Congo." Natural Product Communications 3, no. 12 (2008): 1934578X0800301. http://dx.doi.org/10.1177/1934578x0800301222.

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Extracts obtained from leaves of Aloe barbadensis and A. congolensis, growing in Congo, were analyzed for their in vitro antiradical and anti-yeast activity. Different leaf tissues (tegument and gel) were analyzed separately. Their phenolic fractions showed the presence of chromones and anthrones (aloesin, aloin B, aloin A, and isoaloeresin), flavonoids (apigenin and kaempferol derivatives), and hydroxycinnamic acids. A differential quantitative composition was observed between leaf tegument and gel: in the first, higher concentrations of the four classes of compounds were observed. The extrac

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Shevy, Karunia Cahyaningtias, and Gusti Made Sanjaya I. "Potential of Aloin B Compound and its Derivatives as Type-2 Antidiabetic." International Journal of Current Science Research and Review 06, no. 07 (2023): 3889–99. https://doi.org/10.5281/zenodo.8104509.

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<strong>ABSTRACT: </strong>Type-2 diabetes mellitus occurs due to suboptimal insulin function (insulin resistance) or decreased insulin function. Type-2 diabetes mellitus treatment is chronic and lifelong. One of the treatments is the use of insulin and oral anti-diabetic drugs. This treatment requires a long period of time and can cause unwanted side effects. Therefore, alternative treatments are needed with minimal side effects by utilizing herbal plants containing Aloin B compounds because they have been proven to be used as antidiabetic agents. These compounds can be found from the Aloe Ve

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9

Tewabe, Yitagesu, Belete Kefarge, Habtamu Belay, Daniel Bisrat, Asrat Hailu, and Kaleab Asres. "Antileishmanial Evaluation of the Leaf Latex of Aloe macrocarpa, Aloin A/B, and Its Semisynthetic Derivatives against Two Leishmania Species." Evidence-Based Complementary and Alternative Medicine 2019 (February 24, 2019): 1–6. http://dx.doi.org/10.1155/2019/4736181.

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The currently available antileishmanial drugs are either toxic or too expensive for routine use in developing countries where the disease is most common. Local people in the Somalia region of Ethiopia use the leaves of Aloe macrocarpa Todaro for the treatment of malaria, jaundice, and skin diseases. In our ongoing search for new, efficient, and safe antileishmanial drugs, we investigated the leaf latex of Aloe macrocarpa and its acid-hydrolyzed product aloin A/B (1), as well as the semisynthesized derivatives of aloin A/B, namely, aloe-emodin (2) and rhein (3) against promastigotes and axenica

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10

Rauwald, Hans Wilhelm, Ralf Maucher, Gerd Dannhardt, and Kenny Kuchta. "Dihydroisocoumarins, Naphthalenes, and Further Polyketides from Aloe vera and A. plicatilis: Isolation, Identification and Their 5-LOX/COX-1 Inhibiting Potency." Molecules 26, no. 14 (2021): 4223. http://dx.doi.org/10.3390/molecules26144223.

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The present study aims at the isolation and identification of diverse phenolic polyketides from Aloe vera (L.) Burm.f. and Aloe plicatilis (L.) Miller and includes their 5-LOX/COX-1 inhibiting potency. After initial Sephadex-LH20 gel filtration and combined silica gel 60- and RP18-CC, three dihydroisocoumarins (nonaketides), four 5-methyl-8-C-glucosylchromones (heptaketides) from A. vera, and two hexaketide-naphthalenes from A. plicatilis have been isolated by means of HSCCC. The structures of all polyketides were elucidated by ESI-MS and 2D 1H/13C-NMR (HMQC, HMBC) techniques. The analytical/p

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11

Solaberrieta, Ignacio, Alfonso Jiménez, and María Carmen Garrigós. "Valorization of Aloe vera Skin By-Products to Obtain Bioactive Compounds by Microwave-Assisted Extraction: Antioxidant Activity and Chemical Composition." Antioxidants 11, no. 6 (2022): 1058. http://dx.doi.org/10.3390/antiox11061058.

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Aloe vera skin (AVS) is a major by-product of Aloe processing plants all over the world. In this study, response surface methodology was used to optimize microwave-assisted extraction (MAE) of bioactive compounds from AVS. The influence of extraction parameters, such as ethanol concentration (%Et), extraction temperature (T), time (t) and solvent volume (V), on extraction yield (Y), total phenolic content (TPC), antioxidant activity (DPPH and FRAP methods) and aloin content, was studied. Optimum extraction conditions were determined as 80% ethanol, 80 °C, 36.6 min and 50 mL and optimized extra

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Jia, Yimei, and Jicheng Jia. "Ultraviolet Light Absorption of an Ophthalmic Formulation with Aloe Extracts." Natural Product Communications 4, no. 9 (2009): 1934578X0900400. http://dx.doi.org/10.1177/1934578x0900400915.

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Aloin and polysaccharide present in extracts of Aloe arborescens Miller were formulated into a binary solution to protect eyes from bacterial infection and ultraviolet radiation (UVR). The UVR absorption spectrum was recorded from 190 to 440 nm using a UV spectrometer. The physical properties of the product were examined in terms of its appearance, odor, pH, viscosity, density, refractive index, and stability. The binary solution exhibited three absorption peaks in the UVA, B and C regions, respectively. Such UV absorption capability was attributed to the phenolic chromophores pertaining to al

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13

Malysheva, Svetlana V., Benoît Guillaume, Céline Vanhee, and Julien Masquelier. "Determination of 16 Hydroxyanthracene Derivatives in Food Supplements Using LC-MS/MS: Method Development and Application." Toxins 16, no. 12 (2024): 505. http://dx.doi.org/10.3390/toxins16120505.

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Hydroxyanthracene derivatives (HADs) are plant substances produced by a variety of plant species, including different Aloe, Rheum, and Rhamnus species and Cassia senna. These plants are often used in food supplements to improve bowel function. However, recently, the European Commission prohibited a number of HADs due to toxicological concerns. These HADs included aloin (aloin A and aloin B), aloe-emodin, emodin, and danthron. Most of the currently available analytical methods are restricted to the analysis of only these compounds and do not include other HADs. In this view, a multi-analyte met

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14

Sarwade, Prakash Pralhad, Kavita Narayan Gaisamudre (Sarwade), Rohit Kumar, et al. "A Detailed Study of Aloe Barbadensis Phytochemistry, Taxonomy and Its Anticancer Activity." Journal for Research in Applied Sciences and Biotechnology 4, no. 2 (2025): 77–86. https://doi.org/10.55544/jrasb.4.2.10.

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Aloe barbadensis Mill., the scientific name of which is Aloe vera plant, is an essential perennial succulent plant with tremendous medicinal and pharmacological values. This species falls under the family Asphodelaceae and possesses thick fleshy and lanceolate leaves which are basal and in a rosette structure, the inner parenchyma has gel and the pericyclic region contains yellow latex. For centuries, Aloe barbadensis has been incorporated in different cultures in ethnomedical practices whereby it is used for the management of burns, wound, skin infection and gastrointestinal problems. The pla

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15

Farah, M., R. Andersson, and G. Samuelsson. "Microdontin A and B: Two New Aloin Derivatives fromAloe microdonta." Planta Medica 56, no. 06 (1990): 563. http://dx.doi.org/10.1055/s-2006-961152.

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16

Farah, Mohamed, Rolf Andersson, and Gunnar Samuelsson. "Microdontin A and B: Two New Aloin Derivatives fromAloe microdonta." Planta Medica 58, no. 01 (1992): 88–93. http://dx.doi.org/10.1055/s-2006-961397.

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17

Rauwald, Hans W., Karsten Lohse, and Jan W. Bats. "Bestimmung der Konfiguration der beiden diastereomerenC-Glucosylanthrone Aloin A und B." Angewandte Chemie 101, no. 11 (1989): 1539–40. http://dx.doi.org/10.1002/ange.19891011114.

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18

Forno-Bell, Natalia, Sergio A. Bucarey, Diego García, Daniela Iragüen, Oscar Chacón, and Betty San Martín. "Antimicrobial Effects Caused by Aloe barbadensis Miller on Bacteria Associated with Mastitis in Dairy Cattle." Natural Product Communications 14, no. 12 (2019): 1934578X1989667. http://dx.doi.org/10.1177/1934578x19896670.

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It is known that the primary etiological agents associated with bovine mastitis show high levels of antimicrobial resistance. In this paper, we studied a possible alternative to antimicrobial treatment, Aloe barbadensis Miller ( A. vera). Our goal was to determine the viability of bacteria upon treatment with a methanolic extract of A. vera gel, rich in anthraquinones such as aloin A, aloin B, and aloe emodin. To this purpose, we used fluorescence spectrometry to study the following bacteria: Staphylococcus aureus, Escherichia coli, Streptococcus uberis, and Methicillin-resistant Staphylococcu

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19

Brown, Paula N., Ronan Yu, Chiow Hui Kuan, Jamie Finley, Elizabeth M. Mudge, and Steven Dentali. "Determination of Aloin A and Aloin B in Aloe vera Raw Materials and Finished Products by High-Performance Liquid Chromatography: Single-Laboratory Validation." Journal of AOAC International 97, no. 5 (2014): 1323–28. http://dx.doi.org/10.5740/jaoacint.13-028.

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20

Kline, David, Vicha Ritruthai, Silva Babajanian, et al. "Quantitative Analysis of Aloins and Aloin-Emodin in Aloe Vera Raw Materials and Finished Products Using High-Performance Liquid Chromatography: Single-Laboratory Validation, First Action 2016.09." Journal of AOAC INTERNATIONAL 100, no. 3 (2017): 661–70. http://dx.doi.org/10.5740/jaoacint.16-0387.

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Abstract A single-laboratory validation study is described for a method of quantitative analysis of aloins (aloins Aand B) and aloe-emodin in aloe vera raw materials and finished products. This method used HPLC coupled with UVdetection at 380 nm for the aloins and 430 nm for aloe-emodin. The advantage of this test method is that the target analytes are concentrated from the sample matrix (either liquid or solid form) using stepwise liquid–liquid extraction (water–ethyl acetate–methanol), followed by solvent evaporation and reconstitution. This sample preparation process is suitable for differe

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21

POP, Raluca M., Ion C. PUIA, Aida PUIA, et al. "Pot Aloe vera gel – a natural source of antioxidants." Notulae Botanicae Horti Agrobotanici Cluj-Napoca 50, no. 2 (2022): 12732. http://dx.doi.org/10.15835/nbha50212732.

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Aloe vera (Aloe barbadensis Miller) is widely spread around the world and it is used in the food and cosmetic industry and traditional medicine due to its high content in bioactive compounds. Thus, this article investigated the phenolic compounds of Romanian Aloe vera gel and its antioxidant capacity. The gel was extracted using 4 different solvents: methanol, ethanol, water, and acetone. Total phenolics were measured by the Folin-Ciocalteu method, total flavonoids by aluminium chloride reaction, and the antioxidant capacity by DPPH radical-scavenging activity. The profile of the phenolic comp

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22

Loschi, Francesca, Marta Faggian, Stefania Sut, et al. "Development of an LC–DAD–MS-Based Method for the Analysis of Hydroxyanthracene Derivatives in Food Supplements and Plant Materials." Molecules 27, no. 6 (2022): 1932. http://dx.doi.org/10.3390/molecules27061932.

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Products based on plants containing hydroxyanthracene derivatives (HADs)—such as Rheum, Cassia, and Aloe species—are widely used in food supplements or nutraceuticals due to their laxative effects. A more restricted control of HAD contents in food supplements has been implemented by EU Regulation 2021/468, in order to increase the safety of these preparations. Due to their toxicity, aloin A, aloin B, aloe emodin, emodin, and the synthetic derivative danthron have been listed as prohibited substances in food supplements, being tolerated in amounts < 1 mg kg−1 in marketed products. In this wo

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23

Kurkin, Vladimir Aleksandrovich, Tat'yana Konstantinovna Ryazanova, Anna Anatol'yevna Shmygareva, and Svetlana Nikolayevna Glushchenko. "THE DEVELOPMENT OF METHODS FOR DETERMINATION THE TOTAL OF ANTHRACENE DERIVATIVES IN RAW MATERIALS AND PREPARATIONS OF ALOE ARBORESCENS MILL." chemistry of plant raw material, no. 3 (September 27, 2021): 153–61. http://dx.doi.org/10.14258/jcprm.2021039221.

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Aloe arborescens Mill., family Asphodelaceae, is a pharmacopoeial plant, the raw material of which is used for the production of medicinal products for various therapeutic uses. The standardization of Aloe species in accordance with the requirements of the British, Japanese, European Pharmacopoeias and the United States Pharmacopoeia is carried out according to the barbaloin content by the spectrophotometric method. The methods are multistage, provide for preliminary acid hydrolysis in combination with the oxidation, liquid-liquid extraction of the formed aglycones and subsequent complexation

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Peloso, Mariantonietta, Alessandro Capriotti, Damiano Accurso, Elena Butovskaya, Giorgio Fedrizzi, and Elisabetta Caprai. "UPLC-MS/MS Analysis of Hydroxyanthracene Derivatives in Botanical Food Products and Supplements: Surveillance of the Italian Market." Foods 14, no. 7 (2025): 1229. https://doi.org/10.3390/foods14071229.

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Hydroxyanthracene derivatives (HADs) are natural compounds that occur in several botanical species belonging to the genera Aloe L., Cassia L., Rheum L., Frangula Mill., and Rhamnus L. While they are widely used for their laxative effects, concerns persist about their potential genotoxicity and carcinogenicity. This study presents the development, validation, and application of a sensitive and rapid LC-MS/MS method to detect HAD (aloins, aloe-emodin, emodin, and danthron) levels in botanical food products and supplements. The method was validated according to criteria established by the Europea

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Chouhan, MS*1 Chouhan RS2 Patil BR3 Modi K4 &. Patil S5. "SPECTROSCOPIC AND MICROSCOPIC STUDY OF NATURAL ALOE VERA LEAF AND ITS EXTRACT." GLOBAL JOURNAL OF ENGINEERING SCIENCE AND RESEARCHES [FRTSSDS- June 2018] (June 20, 2018): 225–29. https://doi.org/10.5281/zenodo.1293879.

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The objective of the present study is to evaluate the effect of pasteurization on Ultraviolet light (UV-light) absorption of aloe vera juice (AV juice) and microstructure analysis of dry aloe vera leaf by Scanning Electron Microscopy (SEM). The result showed that unpasteurized aloe vera leaf extract sample (S-1) has higher value of absorbance(0.537) as compare to absorbance(0.248) of pasteurized sample (S-2). SEM images revels that intermolecular cross-linking reduces in drying process which causes low rehydration capacity due to decrease in size and flaccidity of cells and stomata on leaf sur

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Cordiano, Raffaele, Santino Caserta, Paola Lucia Minciullo, Alessandro Allegra, and Sebastiano Gangemi. "Anthraquinones and Aloe Vera Extracts as Potential Modulators of Inflammaging Mechanisms: A Translational Approach from Autoimmune to Onco-Hematological Diseases." Molecules 30, no. 6 (2025): 1251. https://doi.org/10.3390/molecules30061251.

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Inflammaging is a chronic, low-grade inflammatory state that contributes to age-related diseases, including cardiovascular disorders, osteoporosis, neurodegeneration, and cancer. This process involves immunosenescence, oxidative stress, and immune aging, all of which contribute to the breakdown of immune tolerance and the onset of autoimmune disorders. Aloe vera (AV) has recently gained attention for its immunomodulatory, anti-inflammatory, and antioxidant properties. This review explores the effects of AV extracts and anthraquinones (e.g., aloe–emodin, emodin, aloin) on key inflammaging-drive

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27

Lazzara, Silvia, Alessandra Carrubba, Edoardo Napoli, Alessandra Culmone, Anna Concetta Cangemi, and Antonio Giovino. "Increased illumination levels enhance biosynthesis of aloenin A and aloin B in Aloe arborescens Mill., but lower their per-plant yield." Industrial Crops and Products 164 (June 2021): 113379. http://dx.doi.org/10.1016/j.indcrop.2021.113379.

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Tekassa, Tamirat, Yitagesu Tewabe, Daniel Bisrat, Asrat Hailu, and Kaleab Asres. "Antileishmanial activities of leaf latex and compound isolated from Aloe ghibensis Sebsebe & Friis." Ethiopian Pharmaceutical Journal 35, no. 1 (2020): 51–58. http://dx.doi.org/10.4314/epj.v35i1.5.

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Aloe ghibensis Sebsebe & Friis is traditionally used in Ethiopia for the treatment of various ailments including skin problem, wounds and malaria. Phytochemical constituents and antileshimanial properties of the leaf latex of A. ghibensis have not been reported. The objective of this study was, therefore, to determine the phytochemical constituents and in vitro antileishmanial activities of the leaf latex of A. ghibensis and its major compounds against two Leishmania species. Preparative TLC was used to isolate compounds from the leaf latex of A. ghibensis and spectroscopic techniques incl

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Ibrahim, Taofik Adam, Abubeker Hassen, and Zeno Apostolides. "The Antimethanogenic Potentials of Plant Extracts; Their Yields and Phytochemical Compositions as Affected by Extractive Solvents." Plants 11, no. 23 (2022): 3296. http://dx.doi.org/10.3390/plants11233296.

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Plant phytochemicals are an important area of study in ruminant nutrition, primarily due to their antimethanogenic potentials. Plant extract yields, their bioactive compounds and antimethanogenic properties are largely dependent on the nature of the extractive solvents. This study evaluated the yields and phytochemical constituents of four plant extracts, as affected by the aqueous-methanolic (H2O-CH3OH) extraction and their antimethanogenic properties on the in vitro methane production. The plant extracts included Aloe vera, Jatropha curcas, Moringa oleifera, and Piper betle leaves with three

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Quispe, Cristina, Michael Villalobos, Jorge Bórquez, and Mario Simirgiotis. "Chemical Composition and Antioxidant Activity of Aloe vera from the Pica Oasis (Tarapacá, Chile) by UHPLC-Q/Orbitrap/MS/MS." Journal of Chemistry 2018 (December 20, 2018): 1–12. http://dx.doi.org/10.1155/2018/6123850.

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The chemical composition of Aloe vera growing in the small town of San Andrés de Pica, an oasis of warm waters and typical fruits, located in Tamarugal province in the Northern Chilean region of Tarapacá is reported. The chemical characterization was performed using liquid chromatography (UHPLC) coupled to PDA and high-resolution mass spectrometry (HESI-Q-Orbitrap®-MS) in four different plant parts of Aloe (peel, flowers, gel, and roots). Twenty-five phenolic compounds were identified, including cinnamic acids and other derivatives (e.g., caffeic and chlorogenic acids), chromones (e.g., aloesi

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Xiao, Meng-Wei, Xiao-Lin Bai, Yi-Ming Liu, Li Yang, Ya-Dong Hu, and Xun Liao. "Rapid quantification of aloin A and B in aloe plants and aloe-containing beverages, and pharmaceutical preparations by microchip capillary electrophoresis with laser induced fluorescence detection." Journal of Separation Science 41, no. 19 (2018): 3772–81. http://dx.doi.org/10.1002/jssc.201800338.

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Hassanpouraghdam, Mohammad Bagher, Lamia Vojodi Mehrabani, Robab Badali, et al. "Cerium Oxide Salicylic Acid Nanoparticles’ (CeO2: SA-NPs) Foliar Application and In-Soil Animal Manure Use Influence the Growth and Physiological Responses of Aloe vera L." Agronomy 12, no. 3 (2022): 731. http://dx.doi.org/10.3390/agronomy12030731.

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Aloe vera is an economic crop due to the presence of a gel-like substance inside the leaves, which contains polysaccharides, vitamins, proteins, fats, and amino acids. There is an ongoing need for this plant and its products for diverse food and pharmaceutical industries. To meet good agricultural practices, we studied the effect of manure application (0%, 10%, and 20% of v/v of soil) and foliar application with distilled water, salicylic acid (SA, 13.8 mg L−1 equivalent to 100 µM), cerium oxide nanoparticles (CeO2-NPs, 50 mg L−1), and cerium oxide salicylic acid nanoparticles (CeO2: SA-NPs; 1

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Novananda, Panji, Elih Sutisna Yanto, and Reti Puji Handayani. "PEMBUATAN MINUMAN HERBAL DARI LIDAH BUAYA (Aloe vera), LEMON (Citrus limon L) DAN KAYU MANIS (Cinnamomum burmannii) UNTUK PENCAHAR ALAMI." Journal of Holistic and Health Sciences 6, no. 2 (2022): 98–105. http://dx.doi.org/10.51873/jhhs.v6i2.173.

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Latar Belakang: Konstipasi atau sembelit merupakan suatu gangguan proses defekasi yang ditandai dengan berkurangnya frekuensi defekasi kurang dari tiga kali per minggu dengan konsistensi feces yang keras dan disertai rasa tidak enak di dalam pencernaan. Diketahui lidah buaya memiliki efek pencahar (laksatif) karena mengandung 1,8 dihidroksiantrasen glukosida, aloin A dan B (barbaloin) sehingga muncul inovasi untuk memberikan alternatif minuman fungsional yang praktis dan mudah dikonsumsi setiap saat sebagai pencahar alami yang terbuat dari lidah buaya, lemon dan kayu manis. Tujuan Penelitian:

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Watanabe, Masahito. "Discoverer of Alzheimer’s disease: Alois Alzheimer." Journal of allied health sciences 6, no. 2 (2015): 56–61. http://dx.doi.org/10.15563/jalliedhealthsci.6.56.

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Rauwald, Hans W., Karsten Lohse, and Jan W. Bats. "Neue Untersuchung über Inhaltsstoffe aus Aloe- und Rhamnus-Arten, XIII [1] / A New Investigation on Constituents of Aloe and Rhamnus Species, XIII [1]." Zeitschrift für Naturforschung B 46, no. 4 (1991): 551–57. http://dx.doi.org/10.1515/znb-1991-0419.

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Rhamnus purshianus D. C., 10-Hydroxyaloins A/B, Oxanthrone Glucosyls, Quinonoids, AnthranoidsThe absolute configurations of the diastereomeric 10-hydroxyaloins, which may be regarded as parent structures for other naturally occurring oxanthrone-C-glucosyls, have been established as 10R, 16 R (A) and 10 S, 16 R (B) by an X-ray structure analysis of the A-octaacetyl derivative (C 16 is the anomeric glucosyl carbon atom). The determination was confirmed by CD spectroscopic comparison with the structural analogues aloins A and B, which should prove useful for making future configurational assignme

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Cao, Xueli, Danfeng Huang, Yinmao Dong, Hua Zhao, and Yoichiro Ito. "Separation of Aloins A and B from Aloe Vera Exudates by High Speed Countercurrent Chromatography." Journal of Liquid Chromatography & Related Technologies 30, no. 11 (2007): 1657–68. http://dx.doi.org/10.1080/10826070701224887.

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Baumgartner, Christoph, Jakob Baumgartner, Susanne Pirker, and Günter Krämer. "100 Jahre EEG – was war eigentlich nach Hans Berger." Klinische Neurophysiologie 56, no. 01 (2025): 14–22. https://doi.org/10.1055/a-2403-1780.

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ZusammenfassungNachdem Hans Berger 1924 die erste EEG-Ableitung am Menschen durchführte und seine Ergebnisse 1929 publizierte, dauerte es einige Jahre bis Bergers Ergebnisse in der Wissenschaftlichen Community anerkannt wurden und es schließlich zu einer breiten Anwendung des EEGs durch andere Forscher kam. Edgar Douglas Adrian und William Grey Walter führten das EEG in Großbritannien ein. In Deutschland leistete Jan Friedrich Georg Theodor Tönnies grundlegende technische Entwicklungen, wesentliche klinische und tierexperimentelle Studien wurden in Berlin von Alois Kornmüller, Max Heinrich Fis

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Meer, Rudolf. "Cogito, ergo est cogitabile. Cogitabile est, ergo cogito." Studies in Transcendental Philosophy 2, no. 2 (2021): 0. http://dx.doi.org/10.18254/s271326680016819-0.

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Over the last two decades, the controversy between conceptualists and nonconceptualists has provided important insights into Kant’s critical project and especially the transcendental deduction. At the same time, the differentiation of the various positions has led to a seemingly unsolvable paradox in interpretation. However, if the intensifications of the debate are withdrawn and the current positions are placed in the context of historical interpretations, it becomes apparent that a nonconceptualism can indeed be developed without coming into (irresolvable) conflict with Kant’s conceptualism.

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Maul, Michael. ""Die große catholische Messe". Bach, Graf Questenberg und die "Musicalische Congregation" in Wien." Bach-Jahrbuch 95 (March 13, 2018): 153–75. http://dx.doi.org/10.13141/bjb.v20091864.

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Unter Berücksichtigung neuerer Widersprüche gegen das Verständnis der h-moll-Messe BWV 232 als Vermächtniswerk ohne eigentlichen Anlass wird im vorliegenden Artikel, der im Wesentlichen ein Referat des Autors auf dem Symposium „Understanding Bach’s B-minor Mass 2007 in Belfast wiedergibt, eine weitere neue Erklärungsgrundlage für die Vervollständigung der Messe eingeführt. Dazu wird die Person Graf Johann Adam von Questenbergs mit seiner Hofhaltung im mährischen Jarmeritz und ihren Beziehungen zum kaiserlichen Hof in Wien in den Mittelpunkt gestellt. Über die Frage eines möglichen Kontakts zu

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Meyer-Fraatz, Andrea. "Deutschmann, Peter; Herlt, Jens; Woldan, Alois (eds.). “Truth” and Fiction. Conspiracy Theories in Eastern European Culture and Literature. Bielefeld: transcript, 2020. 381 pp." Kritikon Litterarum 50, no. 1-2 (2023): 110–15. http://dx.doi.org/10.1515/kl-2023-0012.

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Vicherová, Šárka. "Pamětní mince a bankovka vydané v roce 2019." Numismatické listy 74, no. 1-4 (2022): 109–22. http://dx.doi.org/10.37520/nl.2019.003.

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The Czech National Bank has produced nine commemorative coins and one banknote in 2019. Four of them were 200 CZK pieces in silver, celebrating the following: 100th Anniversary of the Czechoslovak Red Cross Foundation, 150th Birth Anniversary of Aleš Hrdlička, 100th Anniversary of the construction of the first Czechoslovak-made airplane B-5 and piece to mark the 600th Jubilee of Defenestration of Prague. Furthermore, one jubilee silver piece in a nominal value 500 CZK was issued for the 100th Anniversary of the commencement of the first Czechoslovak currency and a jubilee silver coin with gold

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Manitto, Paolo, Diego Monti, and Giovanna Speranza. "Studies on aloe. Part 6. Conformation and absolute configuration of aloins A and B and related 10-C-glucosyl-9-anthrones." Journal of the Chemical Society, Perkin Transactions 1, no. 5 (1990): 1297. http://dx.doi.org/10.1039/p19900001297.

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Paul, Howard A. "A Review of: “Perlis, M., Aloia, M., & Kuhn, B. (Eds.). (2011).Behavioral Treatments for Sleep Disorders: A Comprehensive Primer of Behavioral Sleep Medicine Interventions.”." Child & Family Behavior Therapy 33, no. 4 (2011): 341–47. http://dx.doi.org/10.1080/07317107.2011.623507.

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Nash, Katie. "Michael J. Aloi, Marjorie Fusco, and Susan E. Ketcham. Digital Collections Worldwide: An Annotated Directory. New York: Neal-Schuman Publishers, Inc., 2011. 345p. alk. paper, $250 (ISBN 9781555707019). LC2011-000445." College & Research Libraries 72, no. 5 (2011): 504–5. http://dx.doi.org/10.5860/0720504.

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Krečmerová, Marcela. "Nucleoside Chemistry at the Institute of Organic Chemistry and Biochemistry – Looking Back on History." Chemické listy 118, no. 6 (2024): 311–20. http://dx.doi.org/10.54779/chl20240311.

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Nucleoside chemistry has been developing at the Institute of Organic Chemistry and Biochemistry (IOCB) since 1957 thanks to the foresight of its first director František Šorm. This new area, targeted especially to oligonucleotide synthesis, earned soon an excellent reputation. At that time IOCB was one of only four institutions in the world successful in oligonucleotide synthesis. First successes in the field of chemically modified nucleosides were syntheses of 6-azauridine as antileukemic agent, 6‑azauridine triacetate investigated as antipsoriatic drug (Riboazauracil) and especially 5‑azacyt

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Zuelke, Andrea E., Steffi G. Riedel-Heller, Felix Wittmann, Alexander Pabst, Susanne Roehr, and Melanie Luppa. "Gender-specific design and effectiveness of non-pharmacological interventions against cognitive decline and dementia–protocol for a systematic review and meta-analysis." PLOS ONE 16, no. 8 (2021): e0256826. http://dx.doi.org/10.1371/journal.pone.0256826.

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Introduction Dementia is a public health priority with projected increases in the number of people living with dementia worldwide. Prevention constitutes a promising strategy to counter the dementia epidemic, and an increasing number of lifestyle interventions has been launched aiming at reducing risk of cognitive decline and dementia. Gender differences regarding various modifiable risk factors for dementia have been reported, however, evidence on gender-specific design and effectiveness of lifestyle trials is lacking. Therefore, we aim to systematically review evidence on gender-specific des

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M. R. Pinheiro, M. R. Pinheiro. "WWI, WWII, Civil War, Vietnam War, Agent Orange and MKULTRA: Cooked in Hell, Served Cold by Satan." International Journal of Humanities and Social Science Invention 14, no. 5 (2025): 56–152. https://doi.org/10.35629/7722-140556152.

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In this piece, we study these remarkably historic events. We present evidence supporting the claim that they were all the result of actions by the satanic brotherhood/sisterhood, which means they were all caused by black African men and/or their black descendants, even though they may have sometimes looked white (change of skin color achieved through the mechanical soul/666) and/or like women (via surgery (the so-called satanic transgenders, members of the satanic sisterhood). We acknowledge the death by murder of the righteous owners of the IDs Kathryn Kuhlman, Gavrilo Princip, Nikola Pašić,

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Ryazanova, T. K., and V. A. Kurkin. "The Use of Reference Materials In the Analysis of Medicinal Plant Raw Materials and Herbal Medicinal Products." Measurement Standards. Reference Materials 19, no. 2 (2023): 47–60. http://dx.doi.org/10.20915/2077-1177-2023-19-2-47-60.

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The need to improve pharmacopoeial approaches to the standardization of medicinal plant raw materials (MPRMs) and herbal medicinal products (HMPs), and the need to ensure the implementation of the principle of «cross-cutting» standardization in the series «medicinal plant raw material – phyto-substance – herbal medicinal product» determine the relevance of developing new, more rational approaches to the analysis of objects of plant origin.The purpose of the research was the theoretical and experimental substantiation of the use of reference materials in the development of assay procedures on t

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Budnyi, Vasyl. "VASYL STEFANYK IN CZECHIA: LIFETIME PERCEPTION IN REVIEWS AND TRANSLATIONS." Слово і Час, no. 2 (April 10, 2022): 55–68. http://dx.doi.org/10.33608/0236-1477.2022.02.55-68.

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The paper traces the perception of Vasyl Stefanyk’s works in Czechia, from the first mention of him by Ivan Franko in the monthly “Slovanský přehled” in 1898 to the obituaries of the writer, who passed away at the end of 1936. The research outlines the genre spectrum of Czech publications concerning Stefanyk’s works (translations; reviews in periodicals; scholarly, educational, and reference editions) and the circle of authors that paid attention to Stefanyk’s writings. In particular, it specifies the authorship of A. Proházka’s and V. Prach’s works assigned by cryptonyms. Stefanyk’s wri

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Bydnyi, Vasyl. "VASYL STEFANYK IN CZECHIA: LIFETIME PERCEPTION IN REWIEWS AND TRANSLATIONS." PRECARPATHIAN BULLETIN OF THE SHEVCHENKO SCIENTIFIC SOCIETY Word, no. 16(63) (August 26, 2022): 335–48. http://dx.doi.org/10.31471/2304-7402-2022-16(63)-335-348.

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The paper traces the perception of Vasyl Stefanyk’s works in Czechia, from the fi rst mention of him by Ivan Franko in the monthly “Slovanský přehled” in 1898 to the obituaries of the writer, who passed away at the end of 1936. Th e research outlines the genre spectrum of Czech publications concerning Stefanyk’s works (translations; reviews in periodicals; scholarly, educational, and reference editions) and the circle of authors that paid attention to Stefanyk’s writings. In particular, it specifi es the authorship of A. Proházka’s and V. Prach’s works assigned by cryptonyms. Stefanyk’s writin

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