Academic literature on the topic 'Alpha amino acids'

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Journal articles on the topic "Alpha amino acids"

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Berkowitz, David B., and Michelle L. Pedersen. "Free .alpha.-Oxiranyl Amino Acids." Journal of Organic Chemistry 60, no. 17 (1995): 5368–69. http://dx.doi.org/10.1021/jo00122a002.

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Shortle, D., and N. Clarke. "Alpha helix propensity of amino acids." Science 262, no. 5135 (1993): 917–18. http://dx.doi.org/10.1126/science.8235616.

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KANAME, Mamoru, Hironori MASHIGE, and Shigeyuki YOSHIFUJI. "Chemical Conversion of Cyclic .ALPHA.-Amino Acids to Cyclic .ALPHA.-Aminophosphonic Acids." CHEMICAL & PHARMACEUTICAL BULLETIN 49, no. 5 (2001): 531–36. http://dx.doi.org/10.1248/cpb.49.531.

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Frenkel-Pinter, Moran, Kaitlin C. Jacobson, Jonathan Eskew-Martin, et al. "Differential Oligomerization of Alpha versus Beta Amino Acids and Hydroxy Acids in Abiotic Proto-Peptide Synthesis Reactions." Life 12, no. 2 (2022): 265. http://dx.doi.org/10.3390/life12020265.

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The origin of biopolymers is a central question in origins of life research. In extant life, proteins are coded linear polymers made of a fixed set of twenty alpha-L-amino acids. It is likely that the prebiotic forerunners of proteins, or protopeptides, were more heterogenous polymers with a greater diversity of building blocks and linkage stereochemistry. To investigate a possible chemical selection for alpha versus beta amino acids in abiotic polymerization reactions, we subjected mixtures of alpha and beta hydroxy and amino acids to single-step dry-down or wet-dry cycling conditions. The re
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Katchalski-Katzir, E. "Synthesis, physicochemical and biological properties of poly-alpha-amino acids--the simplest of protein models." Acta Biochimica Polonica 43, no. 1 (1996): 217–26. http://dx.doi.org/10.18388/abp.1996_4531.

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During the 1950s, linear and multichain poly-alpha-amino acids were synthesized by polymerization of the corresponding N-carboxy-amino acid anhydrides in solution in the presence of suitable catalysts. The resulting homo- and heteropolymers have since been widely employed as simple protein models. Under appropriate conditions, poly-alpha-amino acids, in the solid state and in solution, were found to acquire conformations of an alpha-helix and of beta-parallel and antiparallel pleated sheets, or to exist as random coils. Their use in experimental and theoretical investigations of helix-coil tra
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Hashimoto, Makoto, and Yuta Murai. "Synthesis of Photoreactive Aromatic ^|^alpha;-Amino Acids and Effective Hydrogen-Deuterium Exchange for Aromatic ^|^alpha;-Amino Acids." Journal of Synthetic Organic Chemistry, Japan 72, no. 4 (2014): 360–69. http://dx.doi.org/10.5059/yukigoseikyokaishi.72.360.

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NAGATA, Minoru, and Tsuyoshi KIYOTSUKURI. "Studies on application of .ALPHA.-amino acids to polymers. I. Copolymerization of .ALPHA.-amino acids to nylons." KOBUNSHI RONBUNSHU 48, no. 2 (1991): 111–17. http://dx.doi.org/10.1295/koron.48.111.

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Lubec, B., K. R. Herkner, H. Br�ckner, et al. "Biological activity of alpha-alkyl-amino acids." Amino Acids 1, no. 2 (1991): 289–92. http://dx.doi.org/10.1007/bf00806928.

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Jackson, Richard F. W., Neil Wishart, Anthony Wood, Keith James, and Martin J. Wythes. "Preparation of enantiomerically pure protected 4-oxo .alpha.-amino acids and 3-aryl .alpha.-amino acids from serine." Journal of Organic Chemistry 57, no. 12 (1992): 3397–404. http://dx.doi.org/10.1021/jo00038a030.

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Roos, Eric C., M. Carmen Lopez, Michael A. Brook, et al. "Synthesis of .alpha.-substituted .alpha.-amino acids via cationic intermediates." Journal of Organic Chemistry 58, no. 12 (1993): 3259–68. http://dx.doi.org/10.1021/jo00064a011.

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Dissertations / Theses on the topic "Alpha amino acids"

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Kim, Jin Kyung. "Syntheses of Silanediol Amino acids and alpha-amino-alpha-alkylsilanediol precursors." Diss., Temple University Libraries, 2008. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/16809.

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Chemistry<br>Ph.D.<br>Two research projects are described: studies of the synthesis of alpha-amino-alpha-alkylsilanes, the synthetic precursor of silanediol-based protease inhibitors, and the synthesis and stability evaluation of silanediol amino acids with an unprecedently unhindered silanediol group. Two methods were investigated as approaches to alpha-amino-alpha-alkylsilanes. First, a silicon-substituted aziridine was chosen as the precursor of an alpha-amino-alpha-alkylsilane via ring opening reactions with carbon nucleophiles. Silyl-substituted aziridines 2-24 and 2-30 were prepared
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Hutton, Craig Anthony. "Stereoselective functionalization of [alpha]-amino acids /." Title page, contents and abstract only, 1993. http://web4.library.adelaide.edu.au/theses/09PH/09phh9838.pdf.

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Middleton, Richard John. "Synthesis of unnatural [alpha] - amino acids." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338866.

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Keen, Stephen Philip. "Metal-mediated manipulation of #alpha#-amino acids." Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299177.

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Barrett, D. "Synthetic approaches to #alpha#-amino sulphinic acids." Thesis, University of Newcastle Upon Tyne, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374124.

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Berthelot, Didier. "Synthesis of novel heterocyclic #alpha#-amino acids." Thesis, Open University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367226.

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Razzino, Pasquale. "Asymmetric [alpha]-amino acid synthesis /." Title page, contents and abstract only, 1991. http://web4.library.adelaide.edu.au/theses/09PH/09phr279.pdf.

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Farthing, Christopher Neil. "The synthesis of optically active #alpha#-amino acids." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308737.

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Bunnage, Mark E. "Asymmetric synthesis of #beta#-amino-#alpha#-hydroxy acids." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335769.

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Wishart, Neil. "General approaches to side functionalised #alpha#-amino acids." Thesis, University of Newcastle Upon Tyne, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357082.

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Books on the topic "Alpha amino acids"

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Williams, Robert Michael. Synthesis of optically active [alpha]-amino acids. Pergamon Press, 1989.

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Michael, Smith. Methods of non-[alpha]-amino acid synthesis. M. Dekker, 1995.

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[Alpha]-aminoacid-N-carboxy-anhydrides and related heterocycles: Syntheses, properties, peptide synthesis, polymerization. Springer-Verlag, 1987.

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Soloshonok, V. A. Asymmetric synthesis and application of [alpha]-amino acids. Edited by American Chemical Society Meeting, American Chemical Society. Division of Organic Chemistry, and American Chemical Society. Division of Medicinal Chemistry. American Chemical Society, 2009.

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Hallinan, K. O. Synthetic and metabolic studies on [bēta],[gamma]-unsaturated [alpha]-amino acids. typescript, 1992.

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Fitzpatrick, Teresa. Studies on the serine hydroxymethyltransferase catalysed exchange of the [alpha]-protons of amino acids. University College Dublin, 1998.

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Pan, Qun. Two clusters of acidic amino acids at the amino radical-terminus of complement component C4 [alpha]'-chain are important for C2 binding. National Library of Canada, 2000.

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Martin, O'Donnell, ed. Alpha-amino acid synthesis. Pergamon Press, 1988.

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Brückner, Hans, Hans Br8ckner, and Claudio Toniolo. Peptaibiotics: Fungal Peptides Containing Alpha-Dialkyl Alpha-Amino Acids. Wiley & Sons, Incorporated, John, 2009.

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M, Williams R., and Patrick Perlmutter. Synthesis of Optically Active Alpha-Amino Acids. Elsevier Science & Technology Books, 2013.

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Book chapters on the topic "Alpha amino acids"

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Sapse, Anne-Marie. "The Alpha Factor." In Molecular Orbital Calculations for Amino Acids and Peptides. Birkhäuser Boston, 2000. http://dx.doi.org/10.1007/978-1-4612-1354-3_9.

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Carraher, Charles E., Louis G. Tisinger, and William H. Tisinger. "Titanium-Containing Poly-Alpha-Amino Acids from Dipeptides." In Renewable-Resource Materials. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2205-4_18.

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Lanthorn, Thomas H., Debora A. Dimaggio, Patricia C. Contreras, et al. "Alpha- and Beta-Endopsychosins: Physiological Actions and Interactions with Excitatory Amino Acids." In Neurobiology of Amino Acids, Peptides and Trophic Factors. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-1721-0_13.

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Song, Xiao-Yan, Bin-Bin Xie, Xiu-Lan Chen, and Yu-Zhong Zhang. "Biosynthesis and Molecular Genetics of Peptaibiotics—Fungal Peptides Containing Alpha, Alpha-Dialkyl Amino Acids." In Fungal Biology. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2531-5_11.

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Cabezas, E., L. C. Chiang, and A. C. Satterthwait. "A role for amino acids in the cooperative interactions between an alpha helix nucleation site and appended peptides." In Peptides. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0683-2_92.

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Schomburg, Dietmar, and Margit Salzmann. "Alpha-amino-acid esterase." In Enzyme Handbook 3. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76463-9_39.

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Li, Changhong, Franz M. Matschinsky, and Charles A. Stanley. "Amino Acid-Stimulated Insulin Secretion: The Role of the Glutamine-Glutamate-Alpha-Ketoglutarate Axis." In Monogenic Hyperinsulinemic Hypoglycemia Disorders. KARGER, 2012. http://dx.doi.org/10.1159/000334516.

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Shoshani, Jeheskel, Morris Goodman, John Czelusniak, and Gerhard Braunitzer. "A Phylogeny of Rodentia and Other Eutherian Orders: Parsimony Analysis Utilizing Amino Acid Sequences of Alpha and Beta Hemoglobin Chains." In Evolutionary Relationships among Rodents. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4899-0539-0_7.

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"Amino Acids: Alpha-Amino Protecting Groups." In Solid-Phase Synthesis. CRC Press, 2000. http://dx.doi.org/10.1201/9781482270303-11.

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Rutjes, T., Floris J, Fernando Formaggio, et al. "Aminoamidase-Catalyzed Preparation and Further Transformations of Enantiopure Alpha-Hydrogen- and Alpha,Alpha-Disubstituted Alpha-Amino Acids." In Stereoselective Biocatalysis. CRC Press, 2000. http://dx.doi.org/10.1201/9781420027242.ch2.

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Conference papers on the topic "Alpha amino acids"

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Lefebvre, Isabelle, and Slayton Evans, Jr. "Asymmetric Synthesis of alpha-Amino Phosphonic Acids via the Addition of Phosphites to Enantiopure Sulfinimines." In The 1st International Electronic Conference on Synthetic Organic Chemistry. MDPI, 1997. http://dx.doi.org/10.3390/ecsoc-1-02042.

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Guice, Justin, Morgan Hollins, Caroline Best, Kelly Tinker, and Sean Garvey. "Fungal Multi-enzyme Blend Promotes Improved Macronutrient Hydrolysis of Mixed Meal Substrates in the INFOGEST in vitro Simulation of Digestion." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/fsgu7847.

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Fungal enzymes are often combined in dietary supplements to support digestive health. The purpose of this study was to test the effects of a mixture of 6 fungal enzymes (BC-006) on macronutrient digestion in the INFOGEST static simulation of gastrointestinal digestion in vitro. Substrates included an oral nutritional supplement (ONS), heated test meal (HTM) with grilled chicken, steamed peas, and potatoes, and a canned test meal (CTM) version. BC-006 contains fungal protease (Aspergillus oryzae), acid protease (A. niger), peptidase (A. melleus), lipase (Candida cylindracea), alpha-amylase (A.
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Rawal, Atul, Kristen L. Rhinehardt, and Ram V. Mohan. "Mechanical Behavior of Collagen Mimetic Peptides Under Fraying Deformation via Molecular Dynamics." In ASME 2019 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/imece2019-11492.

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Abstract Collagen is a pervasive, triple helical, extracellular matrix (ECM) protein, found in human body from skin and bones to blood vessels and lungs, making it biocompatible, biodegradable, capable of cell attachment, and relevant for applications in bio-polymers, tissue engineering and a plethora of other bio-medical fields. Natural collagen’s extraction from natural sources is time consuming, sometimes costly, and it is difficult to render, and could present undesired biological and pathogenic changes. Nanoscale collagen mimetic peptides (Synthetic Collagen), without the unwanted biologi
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Lu, Xiumin, Xiaofeng Zhang, Yujie Fu, and Jinxin Xiang. "Interference from alpha-amino acid and protein on determination of formaldehyde in food." In ICMIT 2005: Merchatronics, MEMS, and Smart Materials, edited by Yunlong Wei, Kil To Chong, Takayuki Takahashi, et al. SPIE, 2005. http://dx.doi.org/10.1117/12.664235.

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Qu, Wenwen, Hongwei Tan, Guangju Chen, and Jinhui Peng. "Amino Acid Preference and Stacking Stability of Self-Assembled Cyclic D, L-alpha-Peptide Nanotube." In 2009 2nd International Conference on Biomedical Engineering and Informatics. IEEE, 2009. http://dx.doi.org/10.1109/bmei.2009.5305342.

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Yamamoto, K., H. Kawasaki, K. Suzuki, K. Tanoue, G. Kosaki, and H. Yamazaki. "AMINO ACID SEQUENCE OF THE THROMBIN-BINDING SITE ON PLATELET GLYCOPROTEIN Ib." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642924.

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Amino acid sequence of the thrombin-binding site on platelet glycoprotein (GP) Ib was determined and the effects of the synthesized analogous peptides on thrombin-induced aggregation were studied. Crude platelet membrane fraction solubilized with 5mM dithiothreitol and 0.2% Tween 20 was applied to a WGA-Sepharose. The bound fractions were eluted with 0.3M N-actylglucosamine, then applied to a TM60 ( a monoclonal antibody against GP Ib)-Affi-gel column. Only one GP was bound to the column and was eluted with 50mM glycine-HCl, pH3.0, containing 0.2% Tween 20. SDS-PAGE showed a single band of 130
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Carrell, R. W., P. D. Christey, and D. R. Boswell. "SERPINS: ANTITHROMBIN AND OTHER INHIBITORS OF COAGULATION AND FIBRINOLYSIS. EVIDENCE FROM AMINO ACID SEQUENCES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642896.

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A number of the key inhibitors of coagulation and fibrinolysis have recently been shown to be members of the same superfamily of serine protease inhibitors, the serpins. The archetypes of the group are alpha-l-antitrypsin and antithrombin and it includes antiplasmin, C1-inhibitor, heparin cofactor II and the newly recognised inhibitors of plasminogen activators and activated Protein C. Alignment of their structures shows that they have the same skeletal three-dimensional conformation and, by inference, the same general function mechanisms.The serpins have a reactive centre, primarily dependent
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Lakkaraju, Sirish Kaushik, and Wonmuk Hwang. "Length and Sequence Dependence of the Elasticity of Alpha Helices and Coiled-Coils." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206252.

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Fibrous proteins made by α-helices, one of the most elementary protein secondary structures, have various mechanical roles in a sub cellular environment. An α-helix is wound in a right-handed fashion due to hydrogen bonding between the C=O and the N-H atoms across every i and i+4th residues in the polypeptide chain. Previous approaches characterizing mechanical properties of α-helices treated them as homogenous and linear elastic rods. Stiffness is typically expressed in terms of persistence length lp (∼100nm from Kb∼3×10−28 Nm2, lp = Kb/kT: Kb, the bending stiffness, k the Boltzmann constant
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Plow, E. F., G. A. Marguerie, and M. H. Ginsberg. "RECOGNITION SPECIFICITY OFADHESION RECEPTORS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643728.

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The cytoadhesins are a broadly distributedfamily of structurally, immunologicallyand functionally related cell surface molecules which participate in cellular adhesivereactions. The members of this family are heterodimeric in structure and consist of similar, if not identical, beta subunitsand related, but not identical, alpha subunits. A common functional property of the cytoadhesins is that they possess an arginyl-glycyl-aspartic acid (RGD) recognition specificity which mediates their capacity to act as receptors for adhesive proteins.The above assigned characteristics of thecytoadhesin fami
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Lee, Wing-yiu Jason, Meleri Jones, Peter AC Wing, Swathi Rajagopal, and Graham R. Foster. "O4 Amino acid substitution in genotype 3a hepatitis C virus polymerase protein affects responses to sofosbuvir and interferon alpha and inhibits apoptosis." In BASL Abstracts, 21–23 September, 2020. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2020. http://dx.doi.org/10.1136/gutjnl-2020-basl.4.

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Reports on the topic "Alpha amino acids"

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Gafni, Yedidya, and Vitaly Citovsky. Molecular interactions of TYLCV capsid protein during assembly of viral particles. United States Department of Agriculture, 2007. http://dx.doi.org/10.32747/2007.7587233.bard.

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Tomato yellow leaf curl geminivirus (TYLCV) is a major pathogen of cultivated tomato, causing up to 100% crop loss in many parts of the world. The present proposal, a continuation of a BARD-funded project, expanded our understanding of the molecular mechanisms by which CP molecules, as well as its pre-coat partner V2, interact with each other (CP), with the viral genome, and with cellular proteins during assembly and movement of the infectious virions. Specifically, two major objectives were proposed: I. To study in detail the molecular interactions between CP molecules and between CP and ssDN
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Wisniewski, Michael, Samir Droby, John Norelli, Dov Prusky, and Vera Hershkovitz. Genetic and transcriptomic analysis of postharvest decay resistance in Malus sieversii and the identification of pathogenicity effectors in Penicillium expansum. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597928.bard.

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Use of Lqh2 mutants (produced at TAU) and rNav1.2a mutants (produced at the US side) for identifying receptor site-3: Based on the fact that binding of scorpion alpha-toxins is voltage-dependent, which suggests toxin binding at the mobile voltage-sensing region, we analyzed which of the toxin bioactive domains (Core-domain or NC-domain) interacts with the DIV Gating-module of rNav1.2a. This analysis was based on the assumption that the dissociation of toxin mutants upon depolarization would vary from that of the unmodified toxin should the substitutions affect a site of interaction with the ch
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Gurevitz, Michael, Michael Adams, and Eliahu Zlotkin. Insect Specific Alpha Neurotoxins from Scorpion Venoms: Mode of Action and Structure-Function Relationships. United States Department of Agriculture, 1996. http://dx.doi.org/10.32747/1996.7613029.bard.

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This study was motivated by the need to develop new means and approaches to the design of future, environmentally-safe, insecticides. Utilization of anti-insect selective toxins from scorpion venoms and clarification of the molecular basis for their specificity, are a major focus in this project and may have an applicative value. Our study concentrated on the highly insecticidal toxin, LqhaIT, and was devoted to: (I) Characterization of the neuropharmacological and electrophysiological features of this toxin. (II) Establishment of a genetic system for studying structure/activity relationships
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