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Relevant bibliographies by topics / Alpha Autoradiography

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Journal articles

Academic literature on the topic 'Alpha Autoradiography'

Author: Grafiati

Published: 25 May 2024

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Journal articles on the topic "Alpha Autoradiography"

1

Takekawa, Shoichi, Yoshihiko Ueda, Yoshihiko Ueda, Yoshihiro Hiramatsu, Hirotsugu Munechika, and Fumio Shishido. "Imaging of Beta-Rays from Tissue Blocks with Thorotrast Deposition by Autoradiography using Fuji Computed Radiography." Jurnal Radiologi Indonesia 1, no. 2 (2015): 58–64. http://dx.doi.org/10.33748/jradidn.v1i2.7.

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Background: Autoradiography of tissue with radioactive substance such as Thorotrast by Fuji Computed Radiography (FCR) has been available. We obtained autoradiographs from Thorotrast-deposited tissue by FCR. However, the nature of radiation from tissue with Thorotrast was not certain, because alpha particles are shielded by the plastic front of the FCR cassette. Therefore, we undertook investigation to clearly explain the nature of radiation from Thorotrast in case of autoradiography.Materials and Methods: Tissue blocks of liver and spleen with Thorotrast deposition were imaged by autoradiogra

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2

Carpentier, J. L., D. Brown, B. Iacopetta, and L. Orci. "Detection of surface-bound ligands by freeze-fracture autoradiography." Journal of Cell Biology 101, no. 3 (1985): 887–90. http://dx.doi.org/10.1083/jcb.101.3.887.

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This article describes a new freeze-fracture autoradiographic technique for the detection of radioactive ligands associated with the surface of cells in monolayer or suspension culture. Since freeze-fracture replicas are produced in the conventional way, all membrane features normally seen in freeze-fracture are retained, and autoradiographic grains produced by the labeled ligands are seen superimposed on unaltered exoplasmic membrane fracture faces. To assess the feasibility and resolution of this technique, we compared the surface distribution of alpha 2-macroglobulin and cholera toxin, labe

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3

Stumpf, W. E., J. K. Morin, B. W. Ennis, J. E. Zielinski, and R. B. Hochberg. "Utility of [16 alpha-125I] iodoestradiol for autoradiography for the study of cellular and regional distribution of receptors." Journal of Histochemistry & Cytochemistry 35, no. 1 (1987): 87–92. http://dx.doi.org/10.1177/35.1.3794310.

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We demonstrate the utility of [16 alpha-125I]iodoestradiol for thaw-mount autoradiography with 2 micron and 4 micron thick sections of rat and mouse uterus, pituitary, and brain after in vivo administration. Under the conditions of the experiments, short-term autoradiography with exposure times between 3 and 14 days provides optimal cellular resolution, whereas long-term autoradiography with 1-2 months of exposure may be used to obtain topographic-regional surveys of distribution.

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4

Maltier, J. P., I. Petit, and C. Legrand. "Autoradiographic visualization of alpha 1-adrenergic receptors in cervix of early pregnant rat." Journal of Histochemistry & Cytochemistry 37, no. 5 (1989): 703–7. http://dx.doi.org/10.1177/37.5.2539410.

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alpha 1-Adrenergic receptors were identified, characterized, and localized in rat cervix on Day 6 of pregnancy by autoradiography. Autoradiographic study was performed in slide-mounted rat cervix sections using [3H]-prazosin ([3H]-PRAZ) as ligand. Binding was time dependent and specific. Pharmacological study indicated that specific [3H]-PRAZ binding was inhibited with high affinity by prazosin and phenylephrine and low affinity by yohimbine and clonidine. In cervix, the alpha 1-adrenergic receptors were localized mainly to the inner circular layer of the myometrium. Binding to the outer longi

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5

AL Darwish, Ruqaya, Alexander Hugo Staudacher, Eva Bezak, and Michael Paul Brown. "Autoradiography Imaging in Targeted Alpha Therapy with Timepix Detector." Computational and Mathematical Methods in Medicine 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/612580.

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There is a lack of data related to activity uptake and particle track distribution in targeted alpha therapy. These data are required to estimate the absorbed dose on a cellular level as alpha particles have a limited range and traverse only a few cells. Tracking of individual alpha particles is possible using the Timepix semiconductor radiation detector. We investigated the feasibility of imaging alpha particle emissions in tumour sections from mice treated with Thorium-227 (using APOMAB), with and without prior chemotherapy and Timepix detector. Additionally, the sensitivity of the Timepix d

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6

Koseki, C., Y. Hayashi, S. Torikai, M. Furuya, N. Ohnuma, and M. Imai. "Localization of binding sites for alpha-rat atrial natriuretic polypeptide in rat kidney." American Journal of Physiology-Renal Physiology 250, no. 2 (1986): F210—F216. http://dx.doi.org/10.1152/ajprenal.1986.250.2.f210.

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To determine the intrarenal localization of receptors for atrial natriuretic polypeptide (ANP) in the rat, we performed autoradiography and binding assay by using 125I-labeled alpha-rat ANP (alpha-rANP). Autoradiography at the slice and microscopic level in the kidney and binding assay in isolated glomeruli demonstrated that receptors in the renal cortex were distributed mainly in glomeruli. Although dense silver grains were distributed diffusely both in inner medulla and outer stripe of outer medulla, a marked displacement of the grains was observed only in the inner medulla. Autoradiography

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7

Dvorak, A. M., R. A. Monahan-Earley, H. F. Dvorak, and S. J. Galli. "Ultrastructural cytochemical and autoradiographic demonstration of nonspecific esterase(s) in guinea pig basophils." Journal of Histochemistry & Cytochemistry 35, no. 3 (1987): 351–60. http://dx.doi.org/10.1177/35.3.3819377.

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We used ultrastructural autoradiographic and cytochemical methods to localize esterase activities in unstimulated guinea pig basophils and in basophils undergoing degranulation or recovery from degranulation. We used tritium-labeled diisopropylfluorophosphate (DFP) as a probe for serine enzymes and localized this probe by ultrastructural autoradiography to cytoplasmic granules of immature or mature unstimulated basophils, as well as to granules released by degranulating basophils. Ultrastructural cytochemistry using alpha naphthyl acetate (ANA) as substrate localized nonspecific esterase activ

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8

Kalnins, Christopher A. G., Nigel A. Spooner, Michael J. P. Clarke, and David Ottaway. "Alpha particle autoradiography for high spatial resolution mapping of radionuclides." Journal of Environmental Radioactivity 197 (February 2019): 9–15. http://dx.doi.org/10.1016/j.jenvrad.2018.11.008.

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9

Healy, D. P., and D. D. Fanestil. "Localization of atrial natriuretic peptide binding sites within the rat kidney." American Journal of Physiology-Renal Physiology 250, no. 3 (1986): F573—F578. http://dx.doi.org/10.1152/ajprenal.1986.250.3.f573.

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Although synthetic atrial natriuretic peptides (ANP) have potent natriuretic/diuretic properties, the renal mechanisms underlying these effects are not yet clearly defined. To determine the possible sites of action for ANP within the kidney, we have localized 125I-ANP binding sites by in vitro autoradiography. Slices of rat kidney were incubated with 150 pM 125I-ANP [alpha-rat ANP (alpha-rANP), 28 amino acids] alone or in the presence of 10 nM or 1 microM unlabeled ANP. Autoradiography was performed using LKB Ultrofilm or emulsion-coated cover slips together with histochemical/immunohistochemi

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10

Verdurand, Mathieu, Elise Levigoureux, Sophie Lancelot, et al. "Amyloid-Beta Radiotracer [18F]BF-227 Does Not Bind to Cytoplasmic Glial Inclusions of Postmortem Multiple System Atrophy Brain Tissue." Contrast Media & Molecular Imaging 2018 (2018): 1–7. http://dx.doi.org/10.1155/2018/9165458.

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The accumulation of aggregated alpha-synuclein (α-syn) in multiple brain regions is a neuropathological hallmark of synucleinopathies. Multiple system atrophy (MSA) is a synucleinopathy characterized by the predominant cerebral accumulation of aggregated α-syn as cytoplasmic glial inclusions (CGI). A premortem diagnosis tool would improve early diagnosis and help monitoring disease progression and therapeutic efficacy. One Positron Emission Tomography (PET) study suggested [11C]BF-227 as a promising radiotracer for monitoring intracellular α-syn deposition in MSA patients. We sought to confirm

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