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1

Thurnham, D. I., E. Smith, and P. S. Flora. "Concurrent liquid-chromatographic assay of retinol, alpha-tocopherol, beta-carotene, alpha-carotene, lycopene, and beta-cryptoxanthin in plasma, with tocopherol acetate as internal standard." Clinical Chemistry 34, no. 2 (1988): 377–81. http://dx.doi.org/10.1093/clinchem/34.2.377.

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Abstract A method is described for simultaneously determining retinol, alpha-tocopherol, beta-carotene, alpha-carotene, lycopene, and beta-cryptoxanthin in 0.25 mL of plasma. Plasma mixed with sodium dodecyl sulfate is deproteinized with ethanol containing tocopherol acetate, then extracted with heptane. The evaporated organic layer is reconstituted with mobile phase (methanol/acetonitrile/chloroform, 47/47/6 by vol) and injected onto a 100 x 4.6 mm 3-micron column of Spherisorb ODS-2 (LKB) at 1.5 mL/min. The alpha- and beta-carotenes are well resolved during the 6.5-min run. Retinol is monito
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2

Furusho, Kataoka, Yasuhara, Wada, and Masushige. "Retinol Equivalence of Carotenoids Can be Evaluated by Hepatic Vitamin A Content." International Journal for Vitamin and Nutrition Research 70, no. 2 (2000): 43–47. http://dx.doi.org/10.1024/0300-9831.70.2.43.

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The present study demonstrates a new method to evaluate the bioavailability of carotenoids based on the calculation of the hepatic retinol contents. Weaning male rats of Wistar strain were divided into 5 groups. Each group respectively received retinol acetate (2000–10000 IU per kg diet), alpha-carotene (2400–6000 mug per kg diet), beta-carotene (2400–6000 mug per kg diet), mixture of alpha- and beta-carotenes in the ratio of 1:2 (2400 and 4800 mug per kg diet), and palm-carotene oil (2400–6000 mug per kg diet). The derived retinol equivalences of each carotenoid calculated according to the he
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3

Strauss, Richard. "SERUM CONCENTRATIONS OF ALPHA-TOCOPHEROL, ALPHA-CAROTENE, AND BETA-CAROTENE IN OBESE CHILDREN." Journal of Pediatric Gastroenterology & Nutrition 27, no. 4 (1998): 495. http://dx.doi.org/10.1097/00005176-199810000-00147.

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4

Strauss, Richard. "SERUM CONCENTRATIONS OF ALPHA‐TOCOPHEROL, ALPHA‐CAROTENE, AND BETA‐CAROTENE IN OBESE CHILDREN." Journal of Pediatric Gastroenterology and Nutrition 27, no. 4 (1998): 495. http://dx.doi.org/10.1002/j.1536-4801.1998.tb01336.x.

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5

Sowell, A. L., D. L. Huff, P. R. Yeager, S. P. Caudill, and E. W. Gunter. "Retinol, alpha-tocopherol, lutein/zeaxanthin, beta-cryptoxanthin, lycopene, alpha-carotene, trans-beta-carotene, and four retinyl esters in serum determined simultaneously by reversed-phase HPLC with multiwavelength detection." Clinical Chemistry 40, no. 3 (1994): 411–16. http://dx.doi.org/10.1093/clinchem/40.3.411.

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Abstract We describe the use of HPLC with multiwavelength detection to measure retinol, alpha-tocopherol, lutein/zeaxanthin, beta-cryptoxanthin, lycopene, alpha-carotene, trans-beta-carotene, beta-carotene, and the linoleate, oleate, palmitate, and stearate esters of retinol in a single 200-microL serum sample. The method is sensitive enough to detect individual retinyl esters in fasting serum from a nonhyperlipidemic population and requires only 12 min for each sample. Serum concentration ranges and means are reported for retinol, alpha-tocopherol, lutein/zeaxanthin, beta-cryptoxanthin, lycop
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6

Morinobu, Takao, Takuji Murata, Ryuzo Takaya, and Hiroshi Tamai. "Nutritional Status of beta-Carotene, alpha-Tocopherol and Retinol in Obese Children." International Journal for Vitamin and Nutrition Research 72, no. 3 (2002): 119–23. http://dx.doi.org/10.1024/0300-9831.72.3.119.

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We investigated the concentrations of beta-carotene, alpha-tocopherol, and retinol in obese children, together with assessment of the influence of relative body weight and plasma lipids. A lower plasma beta-carotene level was observed in the obese children, and plasma beta-carotene was inversely correlated with the relative body weight, but not with plasma total lipids. In contrast, the plasma alpha-tocopherol concentration was correlated with plasma total lipids, but not with the severity of obesity. Both the beta-carotene/plasma total lipids ratio and the alpha-tocopherol/plasma total lipids
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7

Kulishova, Ksenia E., and Nataliia V. Rudometova. "Influence of antioxidants on the stability of beta-carotene in multicomplex systems." Processes and Food Production Equipment 15, no. 4 (2022): 3–10. http://dx.doi.org/10.17586/2310-1164-2022-15-4-3-10.

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To prevent further degradation of partially oxidized beta-carotene, inclusion complexes based on beta-cyclodextrin and antioxidants (alpha-tocopherol (vitamin E), ascorbic acid, and vanillin) have been developed. The complexes were obtained by the solid-phase method with intensive stirring for four hours with periodic moistening to the state of a paste, then dried in a desiccator at a temperature of 2…5С, and ground to a powder. The content of beta-carotene in the complexes was determined on a Varian-LC 920 high-performance liquid chromatograph with a Hypersil 5 AA-ODS 200 x 2.1 mm column usi
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8

Lagiou, Benetou, Tebelis, Papas, Naska, and Trichopoulou. "Plasma Carotenoid Levels in Relation to Tobacco Smoking and Demographic Factors." International Journal for Vitamin and Nutrition Research 73, no. 3 (2003): 226–31. http://dx.doi.org/10.1024/0300-9831.73.3.226.

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Antioxidant compounds have been reported to play a beneficial role in the etiology of several chronic diseases. To examine the effects of tobacco smoking and demographic factors on the plasma levels of alpha-carotene, beta-carotene, lycopene, beta-cryptoxanthin, and jointly, lutein-zeaxanthin, we have conducted a cross-sectional study in the context of the Greek segment of the European Prospective Investigation into Cancer and nutrition (EPIC). A random sample of 45 men and 68 women, aged 30–82 years, from the Greek EPIC cohort of 27953 volunteers, provided fasting blood samples and completed
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9

Kiely, Cogan, Kearney, and Morrissey. "Relationship Between Smoking, Dietary Intakes and Plasma Levels of Vitamin E and beta-Carotene in Matched Maternal-cord Pairs." International Journal for Vitamin and Nutrition Research 69, no. 4 (1999): 262–67. http://dx.doi.org/10.1024/0300-9831.69.4.262.

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The concentrations of tocopherols and carotenoids are lowered in umbilical cord blood plasma, which may have a negative effect on antioxidant protection in neonates. Smoking may adversely affect dietary intakes and plasma concentrations of carotenoids. The dietary intakes of vitamin E and beta-carotene were assessed in 66 pregnant women (31 smokers and 35 non-smokers) between 10 and 20 weeks gestation using a food frequency questionnaire. The concentrations of alpha-tocopherol and beta-carotene were measured in maternal plasma at the time of the dietary assessment, and in the matched umbilical
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10

MacCrehan, W. A., and E. Schönberger. "Determination of retinol, alpha-tocopherol, and beta-carotene in serum by liquid chromatography with absorbance and electrochemical detection." Clinical Chemistry 33, no. 9 (1987): 1585–92. http://dx.doi.org/10.1093/clinchem/33.9.1585.

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Abstract We describe a method for the determination of retinol, alpha-tocopherol, and beta-carotene in serum, using a liquid-chromatographic separation with wavelength-programmed ultraviolet/visible absorbance and amperometric electrochemical detection with a glassy carbon electrode. After protein denaturation and addition of an internal standard, tocol, 250-microL samples are twice extracted with hexane. The reversed-phase, gradient-elution chromatographic separation provides baseline resolution of: the all-trans isomer of retinol from the cis isomers, alpha- from gamma-tocopherol, and all-tr
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11

Just*, Brian J., and Philipp W. Simon. "Mapping of Major Carrot Color Genes an Expression of Carotenoid Biosynthetic Genes." HortScience 39, no. 4 (2004): 870B—870. http://dx.doi.org/10.21273/hortsci.39.4.870b.

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While the carotenoid biosynthetic pathway has been studied several horticultural and agronomic crops, very little information exists for this conserved pathway in carrot, a primary source of dietary carotenoids. Though orange carrots are the most familiar color to Western consumers, yellow, red, and white carrots also exist and have been historically important. Modern carrot breeders are showing renewed interest in these unusual color phenotypes. Beta- and alpha-carotene are the primary pigments in orange carrot roots. Yellow carrots accumulate xanthophylls (oxygenated carotenes), red carrots
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12

Zanker, Isa, Harald Hammon, and Jürg Blum. "beta-Carotene, Retinol and alpha-Tocopherol Status in Calves Fed the First Colostrum at 0–2, 6-7, 12-13 or 24-25 Hours after Birth." International Journal for Vitamin and Nutrition Research 70, no. 6 (2000): 305–10. http://dx.doi.org/10.1024/0300-9831.70.6.305.

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Effects on beta-carotene, retinol and alpha-tocopherol status of feeding 1st colostrum at 0–2, 6–7, 12–13 and 24–25 h after birth were studied in calves. beta-carotene, retinol and alpha-tocopherol concentrations decreased in colostrum during the first 2.5 d of laxtation. Plasma beta-carotene, retinol and alpha-tocopherol concentrations in newborn calves were very low. Plasma beta-carotene concentrations increased up to d 3 after the 1st meal and during the 1st month were higher in calves fed 1st colostrum at < 6–7 h than at > 12–13 h after birth. Plasma retinol concentrations increased
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13

Mr., Ghadge Amit Babasaheb. "A review on value-addition to agricultural wastes by extraction of carotenoids with microbial pectinases." International Journal of Advance and Applied Research 10, no. 4 (2023): 473–84. https://doi.org/10.5281/zenodo.8054773.

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Pectinases are biosynthesized by plants, bacteria, algae, and fungi; animals, on the other hand, must consume them from their food. Based on their structural components, carotenoids are divided into two main classes: carotenes, comprised via carbon and hydrogen (for example β-carotene, α-carotene, and lycopene), and xanthophylls, comprised via carbon, hydrogen, and moreover oxygen (for instance lutein, β-cryptoxanthin, zeaxanthin, astaxanthin and fucoxanthin). Pro-vitamin A, antioxidants, cancer prevention, obesity prevention, and anabolic effects on bone components are just a
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14

Silmara, Rondó, Bergamaschi, and Mastroeni. "Smoking during Pregnancy and Plasma Concentrations of beta-Carotene and alpha-Tocopherol in the Immediate Postpartum Period in Brazilian Women." International Journal for Vitamin and Nutrition Research 75, no. 4 (2005): 235–41. http://dx.doi.org/10.1024/0300-9831.75.4.235.

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This study investigated the relationship between plasma concentrations of beta-carotene and the alpha-tocopherol/lipid ratio, and smoking in 233 postpartum women, from July to November 2002, in the city of Joinville, Brazil. Thirty-seven percent (37%) of the women included in this study had low concentrations of alpha-tocopherol (< 11.63 mumol/L) and 61% of the women presented low concentrations of beta-carotene (< 0.39 mumol/L). Multivariate regression analysis investigated the relationship between smoking and the concentration of the vitamins, adjusting by confounding variables. The fi
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15

Trichopoulou, Benetou, Lagiou, Gnardellis, Stacewicz-Sapunzakis, and Papas. "Plasma Carotenoid Levels in Relation to the Mediterranean Diet in Greece." International Journal for Vitamin and Nutrition Research 73, no. 3 (2003): 221–25. http://dx.doi.org/10.1024/0300-9831.73.3.221.

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In the context of the Greek segment of the European Prospective Investigation into Cancer and Nutrition (EPIC), we conducted a cross-sectional study to examine the effects of the intake of plant foods central in the traditional Mediterranean diet on plasma levels of alpha-carotene, beta-carotene, lycopene, beta-cryptoxanthin, and lutein-zeaxanthin. Study subjects were a random sample of 45 men and 68 women, aged 30–82 years, from the Greek EPIC cohort of 27953 volunteers. Linear regression models were fitted, with the carotenoid blood levels as dependent variables. Independent variables were s
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16

Edoh, Ngozi L., Joseph Ukpabi, and John O. Igoli. "Effect of Scopoletin and Carotenoids on Postharvest Physiological Deterioration (PPD) of Transgenic High Beta Carotene Cassava." Journal of Food Research 10, no. 4 (2021): 9. http://dx.doi.org/10.5539/jfr.v10n4p9.

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Cassava tubers suffer from postharvest physiological deterioration (PPD) which normally sets in within 72 hours of harvest. This study examines the role of scopoletin and carotenoids in the onset or delay in PPD in two transgenic varieties EC20-7 and EC20-8 compared to a wild variety TME-7. Scopoletin and carotenoids were quantified by liquid chromatography-mass spectrometry. The scopoletin content (0.10 – 0.20 nmol/g) in the fresh varieties was not significantly (P>0.05) different from the amount in stored cassava roots (12.58 – 14.90 nmol/g). The carotenoid content
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17

Muzáková, Vladimíra, Roman Kand’ár, Milan Meloun, et al. "Inverse Correlation Between Plasma Beta-Carotene and Interleukin-6 in Patients with Advanced Coronary Artery Disease." International Journal for Vitamin and Nutrition Research 80, no. 6 (2010): 369–77. http://dx.doi.org/10.1024/0300-9831/a000024.

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The interrelationships between plasma beta-carotene, alpha-tocopherol, and the level of systemic inflammation and oxidative stress were investigated in patients with advanced coronary artery disease (CAD). Plasma beta-carotene, alpha-tocopherol, malondialdehyde, free radicals, interleukin-6, high sensitive C-reactive protein levels, and other risk factors of CAD were determined in a group of patients with advanced CAD [significant stenosis according to coronarographic examination (n = 91) and a control group of examined patients with coronary arteries with no stenosis (n = 49)]. Between-group
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18

Gómez-Aracena, J., R. Bogers, P. Van’t Veer, et al. "Vegetable Consumption and Carotenoids in Plasma and Adipose Tissue in Malaga, Spain." International Journal for Vitamin and Nutrition Research 73, no. 1 (2003): 24–31. http://dx.doi.org/10.1024/0300-9831.73.1.24.

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Objective: To study relationships between habitual dietary intake, adipose tissue concentrations of alpha-carotene, beta-carotene and lycopene, and plasma concentrations of alpha- and beta-carotene. Design: Cross-sectional study including assessment of food habits by a food frequency questionnaire and 48-hour recall and determination of carotenoid concentrations in adipose tissue and plasma. Subjects: 51 women (mean age of 62 years) from the control group of the European Community Multicentre Study on Antioxidants, Myocardial Infarction, and Breast Cancer (EURAMIC), Málaga, Spain. Results: In
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19

Albanes, D., O. P. Heinonen, J. K. Huttunen, et al. "Effects of alpha-tocopherol and beta-carotene supplements on cancer incidence in the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study." American Journal of Clinical Nutrition 62, no. 6 (1995): 1427S—1430S. http://dx.doi.org/10.1093/ajcn/62.6.1427s.

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20

Middha, Pooja, Stephanie J. Weinstein, Satu Männistö, Demetrius Albanes та Alison M. Mondul. "β-Carotene Supplementation and Lung Cancer Incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: The Role of Tar and Nicotine". Nicotine & Tobacco Research 21, № 8 (2018): 1045–50. http://dx.doi.org/10.1093/ntr/nty115.

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Abstract Introduction The Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study demonstrated that β-carotene supplementation increases lung cancer incidence in smokers. Further, cigarettes with higher tar and nicotine content are associated with a higher risk of lung cancer. However, no studies have examined whether the increased risk associated with β-carotene supplementation in smokers varies by the tar or nicotine content of cigarettes. Methods The ATBC Study was a randomized, double-blind intervention trial conducted in southwest Finland. A total of 29 133 male smokers, aged 50–69
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Milne, D. B., and J. Botnen. "Retinol, alpha-tocopherol, lycopene, and alpha- and beta-carotene simultaneously determined in plasma by isocratic liquid chromatography." Clinical Chemistry 32, no. 5 (1986): 874–76. http://dx.doi.org/10.1093/clinchem/32.5.874.

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Abstract Retinol, alpha-tocopherol, lycopene, and alpha- and beta-carotene can be simultaneously determined in human plasma by reversed-phase liquid chromatography. Plasma--0.5 mL plus added internal standard, retinyl acetate--is deproteinized with 0.5 mL of ethanol, then extracted with 1.0 mL of petroleum ether. The organic layer is removed and evaporated, the residue is redissolved in 0.25 mL of ethanol, and 8-microL samples are injected into a 60 X 4.6 mm column of Hypersil ODS 3-microns particles at 35 degrees C. An isocratic methanol mobile phase, flow rate 0.9 mL/min, is used for the 9-m
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22

Nathania, Nina Regina, Jellyta Pricilla Mantow, Elsa Rahmania Criswahyudianti, Fachrur Rozi Atamimi, and Fatchiyah Fatchiyah. "In-Silico Screening Compounds of Brassica rapa ssp. chinensis as Potential Inhibitor of Neutral Amino Acid Transporter B0AT1 as an Alternative Phenylketonuria Treatment." JSMARTech 2, no. 3 (2021): 113–19. http://dx.doi.org/10.21776/ub.jsmartech.2021.002.03.113.

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Phenylketonuria (PKU) is known as a severe autosomal recessive disease caused by mutations in the expression enzyme, namely the PAH (Phenylalanine Hydroxylase) enzyme that causes the build-up of phenylalanine in the body. Untreated PKU affected brain damage and developmental problems. One of the strategies to reduce phenylalanine in the body is inhibiting B0AT1 activity using carotenoid and terpenoids compounds from Bok choy (Brassica rapa ssp.chinensis). In this study, we evaluated the nine carotenoid and terpenoid compounds from Bok choy as B0AT1 inhibitors. Nine Bok choy compounds, includin
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23

Hughes, Kathryn J., Susan T. Mayne, Jeffrey B. Blumberg, Judy D. Ribaya-Mercado, Elizabeth J. Johnson, and Brenda Cartmel. "Plasma Carotenoids and Biomarkers of Oxidative Stress in Patients with prior Head and Neck Cancer." Biomarker Insights 4 (January 2009): BMI.S2192. http://dx.doi.org/10.4137/bmi.s2192.

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Diets high in fruits and vegetables are generally believed protective against several chronic diseases. One suggested mechanism is a reduction in oxidative stress. The carotenoids, nutrients found in colored fruits and vegetables, possess antioxidant properties in vitro, but their role in humans is less well documented. The aim of this cross-sectional study was to explore the relationships between the most abundant plasma carotenoids (alpha-carotene, beta-carotene, lycopene, lutein, zeaxanthin and beta-cryptoxanthin), as well as grouped carotenoids (total xanthophylls, carotenes and carotenoid
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Breidenassel, Christina, Jara Valtueña, Marcela González-Gross, et al. "Antioxidant Vitamin Status (A, E, C, and Beta-Carotene) in European Adolescents - The HELENA Study." International Journal for Vitamin and Nutrition Research 81, no. 4 (2011): 245–55. http://dx.doi.org/10.1024/0300-9831/a000070.

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Background: An adequate nutritional status of antioxidant vitamins (vitamins A, C, E) and b-carotene is essential especially during childhood and adolescence, because of their important roles in cell growth and development. Currently, there are no physiological reference values for blood concentration of these vitamins and b-carotene in apparently healthy European adolescents. The aim of the current study was to obtain reliable and comparable data of antioxidant vitamins and b-carotene in a cross-sectional study, within HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence), which wa
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Zaman, Z., P. Fielden, and P. G. Frost. "Simultaneous determination of vitamins A and E and carotenoids in plasma by reversed-phase HPLC in elderly and younger subjects." Clinical Chemistry 39, no. 11 (1993): 2229–34. http://dx.doi.org/10.1093/clinchem/39.11.2229.

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Abstract A reversed-phase high-performance liquid-chromatographic method for the simultaneous determination of retinol, alpha-tocopherol, alpha-carotene, beta-carotene, cryptoxanthin, lutein/zeaxanthin, and lycopene is described. This method was applied to plasma measurements in healthy young and elderly subjects. The plasma, deproteinized with ethanol, is extracted twice with n-hexane. After evaporation, the residue is dissolved in 50 microL of tetrahydrofuran and made up to 200 microL with ethanol. Samples (50 microL) are injected onto a 250 x 4.6 mm column of 5-microns-particle Spherisorb O
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26

Jimenez-Jimenez, Felix Javier, Jose Antonio Molina, Fernando Bustos, et al. "Serum levels of beta-carotene, alpha-carotene and vitamin A in patients with Alzheimer's disease." European Journal of Neurology 6, no. 4 (1999): 495–97. http://dx.doi.org/10.1046/j.1468-1331.1999.640495.x.

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Van Kappel, Anne Linda, Jean-Paul Steghens, Anne Zeleniuch-Jacquotte, Véronique Chajès, Paolo Toniolo, and Elio Riboli. "Serum carotenoids as biomarkers of fruit and vegetable consumption in the New York Women's Health Study." Public Health Nutrition 4, no. 3 (2001): 829–35. http://dx.doi.org/10.1079/phn2000115.

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AbstractObjective:To investigate the usefulness of serum carotenoids as biomarkers of fruit and vegetable consumption.Design:Reproducibility study on three repeat measurements of serum carotenoids. Correlation analysis of carotenoids and dietary food intake, and regression analysis of potential predictive parameters for serum carotenoid levels.Setting:New York, USA.Subjects:Women participating in the New York Women's Health Study, a prospective study of sex hormones, diet and breast cancer. Forty-eight women with three repeat blood samples and 302 women having a blood sample and a dietary hist
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Keller, Jessica, Matthew Taylor, Kendra Spaeth, Juleah Littrell, Jeffrey Burns, and Debra Sullivan. "Comparison of Skin Carotenoid Content and Dietary Carotenoid Intake." Current Developments in Nutrition 4, Supplement_2 (2020): 115. http://dx.doi.org/10.1093/cdn/nzaa041_019.

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Abstract Objectives Skin Carotenoid Content (SCC) is a validated biomarker of vegetable intake. The objective of this study is to compare SCC to self-reported diet and supplement intake. Methods This cross-sectional study used baseline data from 61 participants in an ongoing intervention trial (Nutrition Interventions for Cognitive Enhancement). Participants were cognitively normal older adults (≥65 years, MMSE score >25). SCC was determined non-invasively by Resonance Raman spectroscopy (VEGGIE METER®; Longevity Link Corporation). Three measurements were taken on the fingertip and aver
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Herbeth, Bernard, Michel Chavance, Nadine Musse, Luc Mejean, and Gérald Vernhés. "DETERMINANTS OF PLASMA RETINOL, BETA-CAROTENE, AND ALPHA-TOCOPHER0L." American Journal of Epidemiology 132, no. 2 (1990): 394–96. http://dx.doi.org/10.1093/oxfordjournals.aje.a115672.

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Gomez, Georgina, Yadira Cortés, Ana Murillo, et al. "Fruit and Vegetables Carotenoids Intake in Eight Latin American Countries, Results from the ELANS Study." Current Developments in Nutrition 4, Supplement_2 (2020): 107. http://dx.doi.org/10.1093/cdn/nzaa041_011.

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Abstract Objectives To determine carotenoid intake (Beta and alpha carotene, lycopene and beta cryptoxanthin) from fruit and vegetable sources in ELANS participating countries. Methods Data were obtained from the Latin American Health and Nutrition Study (ELANS), a multicenter study developed in urban areas of 8 Latin American countries: Argentina, Brazil, Chile, Colombia, Costa Rica, Ecuador, Peru and Venezuela. Dietary intake among 9218 participants (15- 65 y) was assessed using two 24-hour recall and processed by Nutritional Data System for Research (NDS-R). Fruits and vegetables were class
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Molina, J. A., F. Bustos, F. J. Jiménez-Jiménez, et al. "Serum levels of beta-carotene, alpha-carotene, and vitamin A in patients with amyotrophic lateral sclerosis." Acta Neurologica Scandinavica 99, no. 5 (1999): 315–17. http://dx.doi.org/10.1111/j.1600-0404.1999.tb00682.x.

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32

Wolters, Hermann, and Hahn. "Effects of 6-Month Multivitamin Supplementation on Serum Concentrations of alpha-Tocopherol, beta-Carotene, and Vitamin C in Healthy Elderly Women." International Journal for Vitamin and Nutrition Research 74, no. 2 (2004): 161–68. http://dx.doi.org/10.1024/0300-9831.74.2.161.

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Objective: The aim of this study was to evaluate the effect of supplementation with nutritional doses of antioxidant nutrients on the serum concentrations of ascorbic acid, alpha-tocopherol, and beta-carotene in healthy elderly women. Methods: The study was performed as a randomized placebo-controlled, double-blind trial. Two hundred forty-one free-living, healthy women aged 60 years and older were recruited by newspaper advertisement in Hanover, Germany and its environs. As 21 women dropped out, data of 220 women (aged 60–91 years, median 63 years) were included in this evaluation. Subjects w
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Jianu, Călin, Radu Moleriu, Daniela Stoin, et al. "Antioxidant and Antibacterial Activity of Nepeta × faassenii Bergmans ex Stearn Essential Oil." Applied Sciences 11, no. 1 (2021): 442. http://dx.doi.org/10.3390/app11010442.

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This study was designed to evaluate, for the first time, the antioxidant and antimicrobial activities of Nepeta × faassenii essential oil (NEO). Twenty-six compounds were identified by gas chromatography and mass spectrometry analysis, of which 4a alpha,7alpha,7a alpha-nepetalactone (34.12%), elemol (23.23%), spiro(5,6)dodecane (13.73%), and 3,4 alpha-dihydro-4a alpha, 7 alpha, 7a alpha-nepetalactone (7.93%) were the major compounds. The NEO exhibited broad-spectrum antibacterial effects, and possesses potent antifungal activity on Candida albicans and Candida parapsilosis. NEO’s antioxidant a
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Kuti, J. O. "244 Antioxidant Activity of Opuntia Cactus Pears." HortScience 35, no. 3 (2000): 433B—433. http://dx.doi.org/10.21273/hortsci.35.3.433b.

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Flavonoid content and antioxidant activity in peel and pulp samples of four different cactus pear fruit varieties were investigated. Major cactus fruit flavonoids were quercetin, kaempferol, and isorhamnetin. Greater amount of quercetin was found in the pulp compared with the peel samples in all varieties examined. Both kaempferol and isorhamnetin were found in at least three of the varieties (Opuntia ficus-indica; O. lindheimeri; O. streptacantha) exclusively in the peel samples. Generally, pulp tissue samples of all the cactus fruit varieties contained greater ascorbic acid, glutathione, alp
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Yaşar, Aluç, Kök Osman, and Tüzün İlhami. "PROFILING THE CAROTENOIDS OF MICROALGA (Scenedesmus obliquus) EXTRACT BY HPLC AND ITS ANTIOXIDANT CAPACITY." Journal of Applied Biological Sciences 16, no. 2 (2022): 206–19. https://doi.org/10.5281/zenodo.6590217.

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The extracts of<strong> </strong>the algae species <em>Scenedesmus</em> <em>obliquus </em>isolated<em> </em>from Kapulukaya Reservoir (Kırıkkale, Turkey) were analyzed to determine the composition, content and antioxidant properties of carotenoids. The HPLC analysis was applied to identify carotenoids species and to determine their contents. Methanol&ndash;acetonitrile&ndash;water (84:14:2, v/v/v) and methylene chloride (100%) used in the gradient solvent system resulted in an acceptable separation. Of the 22 resolution peaks assigned to carotenoids either tentatively or positively, the first
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Russell, Robert M. "Beta-carotene and lung cancer." Pure and Applied Chemistry 74, no. 8 (2002): 1461–67. http://dx.doi.org/10.1351/pac200274081461.

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Does beta-carotene increase, rather than decrease, human lung cancer rates? A large body of observational epidemiologic study has demonstrated that individuals who eat more fruits and vegetables rich in carotenoids and/or who have higher levels of serum beta-carotene have a lower risk of cancer, particularly lung cancer. This inverse relationship has been particularly strong in lung cancer patients with a history of heavy smoking. However, there is contradictory evidence from recent human intervention studies using beta-carotene supplements (20­30 mg per day). An increase in risk of lung cance
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Bruno, Renata R., Fernanda C. Rosa, Paula C. Nahas, Flávia M. S. de Branco та Erick P. de Oliveira. "Serum α-Carotene, but Not Other Antioxidants, Is Positively Associated with Muscle Strength in Older Adults: NHANES 2001–2002". Antioxidants 11, № 12 (2022): 2386. http://dx.doi.org/10.3390/antiox11122386.

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Aging is associated with an increased reactive oxygen species that can decrease muscle strength. Thus, antioxidant substances could be positively associated with muscle strength in older adults. To investigate the association between serum antioxidants and muscle strength in older adults. A cross-sectional study evaluating 1172 individuals (627 men and 545 women), aged 50 to 85 years from NHANES 2001–2002, was performed. Carotenoids (α-carotene, trans-β-carotene, cis-β-carotene, β-cryptoxanthin, lutein/zeaxanthin combination, trans-lycopene), vitamin E, and retinol were analyzed via the high-p
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38

Rădulescu, Matilda, Călin Jianu, Alexandra Teodora Lukinich-Gruia, et al. "Chemical Composition, In Vitro and In Silico Antioxidant Potential of Melissa officinalis subsp. officinalis Essential Oil." Antioxidants 10, no. 7 (2021): 1081. http://dx.doi.org/10.3390/antiox10071081.

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The investigation aimed to study the in vitro and in silico antioxidant properties of Melissa officinalis subsp. officinalis essential oil (MOEO). The chemical composition of MOEO was determined using GC–MS analysis. Among 36 compounds identified in MOEO, the main were beta-cubebene (27.66%), beta-caryophyllene (27.41%), alpha-cadinene (4.72%), caryophyllene oxide (4.09%), and alpha-cadinol (4.07%), respectively. In vitro antioxidant properties of MOEO have been studied in 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scaven
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39

Blumberg, Jeffrey. "The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study in Finland." Nutrition Reviews 52, no. 7 (2009): 242–45. http://dx.doi.org/10.1111/j.1753-4887.1994.tb01430.x.

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40

Kobira, Kanta, Khalid Ibrahim, Elizabeth Jefferey, and John Juvik. "(247) Identification of Molecular Markers Associated with Carotenoid and Tocopherol Variability in Broccoli." HortScience 41, no. 4 (2006): 1046A—1046. http://dx.doi.org/10.21273/hortsci.41.4.1046a.

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Considerable epidemiological evidence exists on the association between consumption of antioxidant-rich vegetables and incidence of chronic diseases, including cancer and cardiovascular disease. Broccoli (Brassica oleracea L. sp. italica) florets are relatively abundant sources of antioxidants, and potentially amenable to genetic manipulation to enhance this vegetable's health-promoting properties. This investigation focuses on the identification of chromosomal segments in the nuclear genome of broccoli associated with antioxidant carotenoid and tocopherol variability. A broccoli F2:3 populati
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Ito, Yoshinori, Koji Suzuki, Sadao Suzuki, Ryuichiro Sasaki, Motohiko Otani, and Kunio Aoki. "Serum Antioxidants and Subsequent Mortality Rates of All Causes or Cancer among Rural Japanese Inhabitants." International Journal for Vitamin and Nutrition Research 72, no. 4 (2002): 237–50. http://dx.doi.org/10.1024/0300-9831.72.4.237.

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The purpose of this study was to investigate whether a relationship exists between mortality rates and serum antioxidant levels among Japanese inhabitants. The follow-up subjects, who participated in comprehensive health examinations, consisted of 2444 inhabitants (949 males and 1495 females) of a rural area in Hokkaido, Japan. Between 1991 and December 2000, 146 subjects (94 males and 52 females) died, with cancer accounting for 76 of these deaths (48 males and 28 females). Serum samples at fasting were collected at entry into the study, and serum levels of beta- and alpha-carotenes, lycopene
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Mondul, Alison M., Joshua N. Sampson, Steven C. Moore та ін. "Metabolomic profile of response to supplementation with β-carotene in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study". American Journal of Clinical Nutrition 98, № 2 (2013): 488–93. http://dx.doi.org/10.3945/ajcn.113.062778.

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43

HOMNAVA, A., J. PAYNE, P. KOEHLER, and R. EITENMILLER. "PROVITAMIN A (ALPHA-CAROTENE, BETA-CAROTENE AND BETA-CRYPTOXANTHIN) AND ASCORBIC ACID CONTENT OF JAPANESE AND AMERICAN PERSIMMONS." Journal of Food Quality 13, no. 2 (1990): 85–95. http://dx.doi.org/10.1111/j.1745-4557.1990.tb00009.x.

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44

Hernández-Garduño, Eduardo. "Vitamin E supplementation may transiently increase tuberculosis risk in males who smoke heavily and have high dietary vitamin C intake – comments by Hernández-Garduño." British Journal of Nutrition 101, no. 1 (2008): 145. http://dx.doi.org/10.1017/s0007114508994411.

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Hemilä &amp; Kaprio(1) found a 72 % increase in the risk of tuberculosis (TB) in males taking vitamin E supplements and having high dietary vitamin C intake; the effect was restricted to heavy smokers as part of the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study.
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Comstock, G. W., A. J. Alberg, and K. J. Helzlsouer. "Reported effects of long-term freezer storage on concentrations of retinol, beta-carotene, and alpha-tocopherol in serum or plasma summarized." Clinical Chemistry 39, no. 6 (1993): 1075–78. http://dx.doi.org/10.1093/clinchem/39.6.1075.

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Abstract A literature review of the effects of long-term freezer storage on concentrations of antioxidant micronutrients in serum or plasma showed that a high proportion of the studies that compared the concentrations of retinol, beta-carotene, or alpha-tocopherol in fresh and stored serum were deficient because of small numbers of observations, imprecise descriptions of procedures, and short periods of storage. Data from nested case-control studies of the associations of these micronutrients with cancer are confounded by differences in the study populations. Nevertheless, the overall impressi
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Tabassum, N. "Effect of Alpha-lipoic Acid on the Metabolism of Arsenic in Arsenic-loaded Isolated Liver Tissues of Rat." Journal of Medical Science & Research 12, Number 1 (2009): 3–9. http://dx.doi.org/10.47648/jmsr.2009.v1201.01.

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The patient of chronic arsenic toxicity shows oxidative stress. To overcome the oxidative stress. several antioxidants such as fl-carotene, ascorbic acid, attocopherol, sine and selenium had been suggested. in the present study. universal antioxidant (both water and lipid soluble antioxidant) alpha-lipoic acid was used to examine the effectiveness of this thin( on arsenic metabolism. Alpha-lipoic acid increases the inethylation of inorganic arsenic and releases nionomethylarsenic acid (MMA) and dimethylarstatic acid (DMA) from the haracellular pool. These results suggest that alpha-lipoic acid
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Keskin, Havva, Shao-Ming Wang, Arash Etemadi, et al. "Colorectal cancer in the Linxian China Nutrition Intervention Trial: Risk factors and intervention results." PLOS ONE 16, no. 9 (2021): e0255322. http://dx.doi.org/10.1371/journal.pone.0255322.

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Background Colorectal cancer (CRC) is among the most common cancers in economically developed countries and developing world. While dietary factors are associated with risk of CRC in the West and urban China, little is known about risk or protective factors in rural China. Methods The Linxian General Population Nutrition Intervention Trial (NIT) cohort was established over 30 years ago to test whether daily multivitamin/mineral supplements could reduce the incidence and mortality of esophageal/gastric cardia cancer. The cohort included a total of 29,553 healthy participants 40–69 years old who
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Drescher, Jennifer N., Joseph Sherma, and Bernard Fried. "Thin Layer Chromatographic Determination of Alpha-Carotene on Magnesium Oxide Layers." Journal of Liquid Chromatography 16, no. 16 (1993): 3557–61. http://dx.doi.org/10.1080/10826079308019708.

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Törnwall, Markareetta E., Jarmo Virtamo, Pasi A. Korhonen, Mikko J. Virtanen, Demetrius Albanes, and Jussi K. Huttunen. "Postintervention Effect of Alpha Tocopherol and Beta Carotene on Different Strokes." Stroke 35, no. 8 (2004): 1908–13. http://dx.doi.org/10.1161/01.str.0000131750.60270.42.

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Charoensiri, R., R. Kongkachuichai, S. Suknicom, and P. Sungpuag. "Beta-carotene, lycopene, and alpha-tocopherol contents of selected Thai fruits." Food Chemistry 113, no. 1 (2009): 202–7. http://dx.doi.org/10.1016/j.foodchem.2008.07.074.

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