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Relevant bibliographies by topics / Alpha glycosidase

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Academic literature on the topic 'Alpha glycosidase'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Alpha glycosidase"

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M., Amin Mir* Yangchan Dolma Tsering Yangchan Jigmat Stanzin Bilal Ahmad Mir. "ANTIDIABETIC PROPERTIES OF VARIOUS EXTRACTS OF HIPPOPHAE RHAMNOIDE." Indo American Journal of Pharmaceutical Sciences 04, no. 11 (2017): 4507–715. https://doi.org/10.5281/zenodo.1068273.

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The various extracts of Hippophae rhamnoide plant have been scrutinized for the anti-diabetic property by the use of alpha-amylase and alpha glycosidase enzymes inhibition method. The various parts of the plant have been extracted by Soxhlet extraction method, in which various solvents have been used in the order of their increasing polarity like Petroleum ether, Ethanol and Water. Acarbose have been used as a reference antidiabetic medicine by the inhibition of alpha-amylase and alpha glycosidase enzyme, the two key enzymes responsible for the degradation of higher carbohydrates into lower gl

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Sha, Bi Ying, Qing Shan Liu, Lin Cheng, and Xiao Ying Yin. "Preparation and Application of Core-Shell PMMA/Chitosan Nanoparticle." Advanced Materials Research 535-537 (June 2012): 271–74. http://dx.doi.org/10.4028/www.scientific.net/amr.535-537.271.

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Abstract: Objective To separate and enrich compounds from Apocynum venetum L. leaves. Methods The core-shell nanoparticles consisting of poly (methyl methacrylate) (PMMA) cores surrounded by various chitosan shells, induced by a tert-butylhydroperoxide (TBHP) solution. And core-shell nanoparticles was applied to immobilize Alpha glycosidase enzymes. Some compound from the extrat of Apocynum venetum L. leaves were absorbed by the immobilized Alpha glycosidase enzymes. and the components absorbed were detected by HPLC. Results Hyperoside and trifolin can be adsorbed by the nanoparticles immobili

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al Daher, S., G. Fleet, S. K. Namgoong, and B. Winchester. "Change in specificity of glycosidase inhibition by N-alkylation of amino sugars." Biochemical Journal 258, no. 2 (1989): 613–15. http://dx.doi.org/10.1042/bj2580613.

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The synthetic amino sugar 1,4-dideoxy-1,4-imino-L-allitol (DIA) is a moderately good inhibitor of human liver alpha-D-mannosidases and a weak inhibitor of alpha-L-fucosidase, N-acetyl-beta-D-hexosaminidase and beta-D-mannosidase. Methylation of the ring nitrogen of DIA markedly decreases the inhibition of all the glycosidases except N-acetyl-beta-D-hexosaminidase. N-Benzylation of DIA essentially abolishes all inhibitory activity, except towards alpha-L-fucosidase, which is more strongly inhibited than by either DIA or N-methyl-DIA. This is the first report of a change of specificity of inhibi

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Rura, Sarniati Rante, Yulia Yusrini Djabir, Abdul Rahim, Sri Ningsih, and Nisrina Firdausi. "Evaluation of the Anti-Diabetic Activity of Paliasa Leaf Ethanol Fraction (Kleinhovia hospita L) Through Inhibition of the Enzymes $\alpha$-Glucosidase and $\alpha$-Amylase." Jurnal Ilmiah Kesehatan (JIKA) 5, no. 2 (2023): 342–51. http://dx.doi.org/10.36590/jika.v5i2.509.

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Kleinhovia hospita has long been used to treat diseases, including diabetes mellitus. This study aimed to evaluate if the hypoglycemic effects of K. hospita extract and fractions were related to its inhibition on the activity of $\alpha$-amylase and $\alpha$-glycosidase enzymes. K. hospita leaves were extracted with 96% ethanol and then subjected to liquid-liquid partition using n-hexane, ethyl acetate, and water as solvents. The inhibitory capacity of ethanolic extract and its fractions were tested against $\alpha$-amylase and $\alpha$-glycosidase enzyme activity and compared to acarbose. The

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Widyawati, Paini Sri, Yesiana D. W. Werdani, and Christine Setiokusumo. "IN VITRO ANTIOXIDANT CAPACITIES AND ANTIDIABETIC PROPERTIES OF PLUCHEA LEAVES AND GREEN TEA MIXTURES AT VARIOUS PROPORTIONS." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 8 (2017): 203. http://dx.doi.org/10.22159/ijpps.2017v9i8.19545.

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Objective: This study was done to determine the effect of pluchea leaves and green tea mixtures at various proportions to antioxidant and antidiabetic properties.Methods: The research used a single factor randomized block design. Research factors were pluchea and green tea mixture proportions, including 100:0; 75:25; 50:50; 25:75; and 0:100% (w/w), respectively. Each of factors was repeated five times. The parameters observed in this study were phytochemical compounds, total phenols, total flavonoids, free radical DPPH scavenging activity, iron ion reducing power, alpha amylase and alpha glyco

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Field, R. A., A. H. Haines, E. J. T. Chrystal, and M. C. Luszniak. "Histidines, histamines and imidazoles as glycosidase inhibitors." Biochemical Journal 274, no. 3 (1991): 885–89. http://dx.doi.org/10.1042/bj2740885.

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This present study reports the ability of a range of derivatives of L-histidine, histamine and imidazole to act as inhibitors of sweet-almond β-glucosidase, yeast alpha-glucosidase and Escherichia coli β-galactosidase. The addition of a hydrophobic group to the basic imidazole nucleus greatly enhances binding to both the alpha- and β-glucosidases. L-Histidine (beta-naphthylamide (Ki 17 microM) is a potent competitive inhibitor of sweet-almond β-glucosidase as is omega-N-acetylhistamine (K1 35 microM), which inhibits the sweet-almond β-glucosidase at least 700 times more strongly than either ye

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Yan, Lin, Haiwei Xu, Fengwu Liu, Jin Zhao, and Hongmin Liu. "Synthesis and Biological Evaluation of Andrographolide C-Glycoside Derivatives as α-Glycosidase Inhibitors." Chinese Journal of Chemistry 30, no. 4 (2012): 914–18. http://dx.doi.org/10.1002/cjoc.201100179.

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Ortíz-Martinez, David Mizael, Catalina Rivas-Morales, Myriam Angelica de la Garza-Ramos, Maria Julia Verde-Star, Maria Adriana Nuñez-Gonzalez, and Catalina Leos-Rivas. "Miconiasp. Increases mRNA Levels of PPAR Gamma and Inhibits Alpha Amylase and Alpha Glucosidase." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/5123519.

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Diabetes mellitus is a public health problem worldwide. For this reason, ethanolic extract ofMiconiasp. from Oaxaca, Mexico, was selected in search of an alternative against this disease. The effect ofMiconiasp. on mRNA expression of PPARγon cell line 3T3-L1, its effect on alpha amylase and alpha glucosidase, lipid accumulation during adipogenesis, and cell viability on VERO cells were evaluated. The mRNA levels of PPARγincreased on1.393±0.008folds, lipid accumulation was increased by 29.55% withMiconiasp. extract and 34.57% with rosiglitazone, andα-amylase andα-glycosidase were inhibited with

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Amin Mir, M., Shalini Upadhay, and Bilal Ahmad Mir. "Inhibition of Alpha Amylase and Alpha Glycosidase Enzymes by Various Earth Worm Extracts." Biomedical and Pharmacology Journal 11, no. 3 (2018): 1261–68. http://dx.doi.org/10.13005/bpj/1487.

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The earth worm extracts have been analysed for the inhibition of alpha amylase and alpha glycosidase enzymes, which are the key enzymes for the control of glucose in the human system so have direct impact upon the health of an organism. These two enzymes have direct involvement in the diabetic process. So the inhibition of these two enzymes helps in the reduction of diabetes. Various extracts of the earth worms, viz, Ethyl acetate, Acetone, DMSO, Ethanol and Water have been analysed against the inhibition of the respective enzymes. Among the various extracts it had been found that water extrac

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Kimura, Atsuo, Toshiyuki Nishio, Wataru Hakamada, et al. "Affinity Labelling of Glycosidase by .OMEGA.-Epoxyalkyl .ALPHA.-Glucoside." Journal of Applied Glycoscience 47, no. 2 (2000): 235–41. http://dx.doi.org/10.5458/jag.47.235.

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Dissertations / Theses on the topic "Alpha glycosidase"

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Smith, Nigel K. "The synthesis of novel oligosaccharides using the glycosidase #alpha#-mannosidase." Thesis, University of Westminster, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362691.

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Lodge, Jacinta. "The crystal structure of [alpha]-glucosidase [alpha-glucosidase] A, AglA, from Thermotoga maritima the first structure of a family 4 glycosyl hydrolase defines a new glycosidase clan /." [S.l. : s.n.], 2003. http://www.diss.fu-berlin.de/2004/95/index.html.

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Glawar, Andreas Felix Gregor. "Design, synthesis and biological evaluation of glycosidase inhibitors in an anti-cancer setting." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:602edf26-d9ff-4fcf-8dec-c8548f3578da.

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The aim of the work described in this thesis was to explore the synthesis of glycosidase inhibitors and to evaluate their potential as anti-cancer agents. Glycosidases catalyze the fission of glycosidic bonds and are involved in vital biological functions. With regard to their potential for anti-cancer therapy, two glycosidases were identified: α-N-acetyl-galactosaminidase and β-N-acetyl-hexosaminidase. The former has been implicated in causing immunosuppression in advanced cancer patients by negating the effect of the macrophage activating factor (MAF), while the latter is secreted by invadin

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Souza, Ana Marla Duarte de. "Compostos bioativos com potencial ação no controle da homeostase glicêmica." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/9/9131/tde-05062017-165732/.

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Diversos estudos buscam identificar novas moléculas com ações regulatórias sobre a via de sinalização da insulina e consequentemente na homeostase da glicose. Assim, este trabalho visa avaliar o potencial de extratos de frutos no controle da homeostase glicêmica. Os frutos avaliados foram o morango (cv. Toianoca, Camarosa, Oso Grande e Camino Real), a amora-preta e a framboesa vermelha, em dois tempos de amostragem, sendo considerado como tempo A1 e tempo A2. As amostras foram caracterizadas quanto ao seu conteúdo de fenólicos totais, conteúdo de antocianinas monoméricas, capacidade antioxidan

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Al-kandari, Sharifa. "Purification, characterization, and hydrolytic activity of alpha-galactosidase from Lactobacillus helveticus ATCC 10797." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97889.

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In this study, alpha-Galactosidase (alpha-D-galactoside-galactohydrolase, EC 3.2.1.22) has been isolated, purified, and characterized from intracellular fraction of Lactobacillus helveticus ATCC 10797. It was purified by a combination of ammonium sulfate precipitation and fast performance liquid chromatography system using ion exchange and gel-filtration columns. This enzyme was purified to only 9.44 fold over the crude extract with a recovery of 1.8%. The km of 3.83 mM and Vmax of 416.44 mumol/min/mg protein were calculated from PNPG. The molecular mass was estimated to be 188 kDa by gel-filt

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Schuff, Brandon Patrick. "Palladium (II)-catalyzed stereoselective formation of [alpha]-O-glycosides." Thesis, Montana State University, 2007. http://etd.lib.montana.edu/etd/2007/schuff/SchuffB0507.pdf.

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Arab-Jaziri, Faten. "Etudes structures/Fonctions et Ingénierie de l'alpha-L-arabinofuranosidase de Thermobacillus Xylanilyticus." Thesis, Toulouse, INSA, 2012. http://www.theses.fr/2012ISAT0053/document.

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Dans ce projet de thèse, une variété de techniques a été employée pour étudier l’alpha-L-arabinofuranosidase de Thermobacillus xylanilyticus (TxAbf), notamment en ce qui concerne les relations structure/fonctions et son activité de transglycosylation. Nos travaux ont eu pour objectif d’apporter un éclairage quant au rôle de la dynamique dans l’activité catalytique de la TxAbf, en se focalisant sur le mouvement de la boucle bêta2alpha2, et d’explorer la spécificité du sous-site [+1], un élément du site actif qui est particulièrement pertinent pour l’activité de transglycosylation. Enfin, nous a

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Osanjo, George Oyamo. "Évolution dirigée de l'alpha-L-fucosidase de Thermotoga maritima en alpha-L-transfucosidase et application à la synthèse regiosélective d'oligosaccharides." Nantes, 2008. http://www.theses.fr/2007NANT2132.

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Les glycanes, en particulier, les oligosaccharides fucosylés (FucOS), sont de plus en plus reconnus pour leurs rôles biologiques clés. Ces oligosaccharides sont impliqués dans les processus biomoléculaires tels que les communication intercellulaires, la régulation de la croissance, les processus inflammatoires, la différentiation cellulaire, la fertilisation, et les métastases de cancers. Chez l’homme, les déterminants du groupe sanguin d’ABO ainsi que ceux de Lewis sont des glycotopes fucosylés. Ces composés et leurs analogues suscitent désormais un grand intérêt scientifique vu leur potentie

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Chinnathambi, S. "Isolation, purification and characterization of alpha- arabinofuranosidase and other glycosidases from sclerotium rolfsii." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1997. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3289.

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McKay, Matthew Joseph. "Applications of cationic transition-metal-catalysis : the stereoselective synthesis of beta-O-aryl glycosides and alpha-urea glycosides." Diss., University of Iowa, 2014. https://ir.uiowa.edu/etd/4692.

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Having access to mild and operationally simple techniques for attaining carbohydrate targets will be necessary to facilitate advancement in biological, medicinal, and pharmacological research. Even with the abundance of elegant reports for generating glycosidic linkages, the stereoselective construction of alpha- and beta-oligosaccharides and glycoconjugates is by no means trivial. In an era when expanded awareness of the impact we are having on the environment drives the state-of-the-art, synthetic chemists are tasked with developing cleaner and more efficient reactions for achieving their tr

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Books on the topic "Alpha glycosidase"

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Baumann, Pierre. Alpha Dl-Acid Glycoprotein: Genetics, Biochemistry, Physiological Functions, & Pharmocology. John Wiley & Sons Inc, 2000.

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Drug Concentration Monitoring Microbial Alpha-Glucoside Inhibitors Plasminogen Activators (Progress in Clinical Biochemistry and Medicine, Vol 7). Springer, 1988.

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Book chapters on the topic "Alpha glycosidase"

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Fang, Jun, Qunfang Tang, Long Liu, and Jianghua Li. "Enhanced Solvent-Stable Alpha Glycosidase Production by Bacillus licheniformis JXC-1 by Optimization of Feeding Strategies." In Lecture Notes in Electrical Engineering. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-46318-5_34.

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Sugimoto, Kazuhisa, Takahisa Nishimura, Koji Nomura, Hiromi Nishiura, and Takashi Kuriki. "Enzymatic Synthesis of Glycosides Using Alpha-Amylase Family Enzymes." In Biocatalysis and Biomolecular Engineering. John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470608524.ch28.

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Mazzoli, Roberto, and Enrica Pessione. "Ancient Textile Deterioration and Restoration: Bio-Cleaning of an Egyptian Shroud Held in the Torino Museum." In Microorganisms in the Deterioration and Preservation of Cultural Heritage. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-69411-1_9.

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AbstractAncient textiles are fragile and several factors can affect their integrity. In the present chapter, the main agents of deterioration of old and new textiles, namely physical-chemical (light, oxygen, heat, and humidity) and biological factors as well as human erroneous interventions will be explored. As far as the biological deterioration is considered, the effects of microbial growth, primary and secondary metabolites (acids, solvents, surfactants, pigments) and enzymes (lipases, proteases, and glycosidases) on textile strength and cleanliness will be described in details. The main fu

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Yang, X., J. Y. H. Toy, Z. Song, and D. Huang. "Digestive Enzyme Inhibitors for Weight Management: Resin Glycosides/Lipase Inhibitors and Flavone Oligomers/Alpha-amylase Inhibitors." In Evidence-based Nutraceuticals and Functional Foods. Royal Society of Chemistry, 2025. https://doi.org/10.1039/9781837674046-00211.

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In the context of the escalating global obesity crisis, this chapter delves into innovative strategies for combating excessive weight gain, focusing on the pivotal role of pancreatic lipase inhibition. The prevalence of obesity has reached alarming levels, causing severe health issues and over 2.6 million annual deaths. Existing anti-obesity drugs, such as orlistat, can cause undesirable side effects, thereby requiring the exploration of alternative lipase inhibitors with low to no side effects. This study comprehensively examines microbial, fungal, marine, and plant-derived inhibitors, spotli

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Goel, Ms Neha. "Source, Name of Marker Compounds and Their Chemical Nature, Medicinal Uses and Health Benefits of Following Used as Nutraceuticals/Functional Foods-II." In Edited Book of Dietary Supplements and Nutraceuticals [According to latest syllabus of B. Pharm-VIII Semester of Pharmacy Council of India]. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/nbennurdsch4.

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This section of Nutraceuticals-II explores the nutraceutical and functional food applications of Garlic, Broccoli, Ginkgo, and Flaxseeds, focusing on their source, marker compounds, chemical nature, medicinal uses, and health benefits. Garlic, derived from *Allium sativum*, is rich in allicin, a sulfur-containing compound with potent antioxidant and antimicrobial properties, known for its cardiovascular benefits, including lowering blood pressure and cholesterol levels. Broccoli, a cruciferous vegetable, contains sulforaphane, a sulfur-rich compound that supports detoxification processes and o

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Vasantha, S., A. Subramaniyan, S. V. Bakiya Lakshmi, P. Vanathi, and C. Karpaga Sundari. "COMPARATIVE ANALYSIS OF BIOACTIVE COMPOUNDS IN DRY BLACK AND GREEN GRAPES VITIS VINIFERA (L.) BY GC-MS." In Futuristic Trends in Agriculture Engineering & Food Sciences Volume 3 Book 10. Iterative International Publisher, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bcag10p1ch5.

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The study indented to examine the therapeutic potentials of V. vinifera through GC/MS characterization. The ethanolic extracts of Black and Green dry grapes were undergone qualitative analysis. The consequences of qualitative phytochemical analysis of black and green grapes extracts confirmed the occurrence of alkaloids, flavonoids, glycosides, saponins, tannins, carbohydrates, phytosterol, and triterpenoids, whereas flavonoids were absent in green grapes. The black dry grape possessed Antioxidant, hypocholesterolemic, Antiandrogenic, hemolytic, Alpha reductase inhibitor, Anti-inflammatory, An

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Conference papers on the topic "Alpha glycosidase"

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Aghajari, Nushin, Michel Roth, and Richard Haser. "EVIDENCE OF OLIGOSACCHARIDE SYNTHESIS BY CRYSTALS OF A COLD-ACTIVE ALPHA-AMYLASE: CHARACTERIZATION OF A NEW ALPHA-GLYCOSIDASE INHIBITOR." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.588.

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Yakovishin, L. A., and E. N. Korzh. "New supramolecular complex of quercetin with triterpene glycoside alpha-hederin." In ACTUAL PROBLEMS OF ORGANIC CHEMISTRY AND BIOTECHNOLOGY (OCBT2020): Proceedings of the International Scientific Conference. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0068899.

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