Academic literature on the topic 'Alpha -lycorane'

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Journal articles on the topic "Alpha -lycorane"

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Baeckvall, Jan E., Pher G. Andersson, Guy B. Stone, and Adolf Gogoll. "Synthesis of (.+-.)-.alpha.- and (.+-.)-.gamma.-lycorane via a stereocontrolled organopalladium route." Journal of Organic Chemistry 56, no. 9 (1991): 2988–93. http://dx.doi.org/10.1021/jo00009a011.

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Oppolzer, Wolfgang, Alan C. Spivey, and Christian G. Bochet. "Suprafaciality of Thermal N-4-Alkenylhydroxylamine Cyclizations: syntheses of (.+-.)-.alpha.-Lycorane and (+)-Trianthine." Journal of the American Chemical Society 116, no. 7 (1994): 3139–40. http://dx.doi.org/10.1021/ja00086a060.

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Liu, Jing, Ji-liang Hu, Bi-Wei Shi, Yang He, and Wei-Xin Hu. "Up-regulation of p21 and TNF-alpha is mediated lycorine-induced death of HL-60 cells." Cancer Cell International 10, no. 1 (2010): 25. http://dx.doi.org/10.1186/1475-2867-10-25.

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Zhu, Qi, Xu-xu Zhuang, Jia-yue Chen, et al. "Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models." Phytomedicine 87 (July 2021): 153578. http://dx.doi.org/10.1016/j.phymed.2021.153578.

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Gan, Yi, Ai’e He, Lilei Zhu, Yao Yao та Chunhua Lv. "Lycorine impedes 7,12-dimethylbenz(a)anthracene exposed hamster oral carcinogenesis through P13K/Akt and NF-κB inhibition". Turkish Journal of Biochemistry, 17 червня 2022. http://dx.doi.org/10.1515/tjb-2021-0284.

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Abstract Objectives Oncogenic signaling pathways that are activated abnormally play a key activity in tumor initiation and development. This research aimed to examine the preventive efficiency of lycorine in the buccal pouch hamster tumor model based on its capacity to target phosphoinositide 3-kinase (PI3K)/Akt and nuclear factor-kappa B (NF-κB) signaling cascades. Methods The induction of oral tumor in male golden Syrian hamsters was done by 7,12-dimethylbenz [a] anthracene (DMBA) painting on the left buccal pouch thrice a week for 10 weeks. The chemopreventive effect of lycorine (20 mg/kg b
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Javadi, Behjat, and Mahdi Khodadadi. "A Review of the Protective Effects of Alkaloids Against Alpha-synuclein toxicity in Parkinson's disease." Mini-Reviews in Medicinal Chemistry 24 (June 13, 2024). http://dx.doi.org/10.2174/0113895575306884240604065754.

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Background: Alpha-synuclein (α-syn) aggregation products may cause neural injury and several neurodegenerative disorders (NDs) known as α-synucleinopathies. Alkaloids are secondary metabolites present in a variety of plant species and may positively affect human health, particularly α-synucleinopathy-associated NDs. Aim: To summarize the latest scientific data on the inhibitory properties of alkaloids in α- synucleinopathies, especially in Parkinson’s disease. Methods: Literature search was performed using web-based databases including Web of Science, PubMed, and Scopus up to January 2024, in
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Shaala, Lamiaa A., Diaa T. A. Youssef, Mahmoud A. Ramadan, et al. "Molecular mechanisms of phytoconstituents from selected Egyptian plants against non-small cell lung cancer using integrated in vitro network pharmacology and molecular docking approach." Naunyn-Schmiedeberg's Archives of Pharmacology, January 31, 2025. https://doi.org/10.1007/s00210-025-03834-4.

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Abstract Non-small cell lung cancer (NSCLC) is a widespread highly malignant type of lung cancer. Conventional chemotherapeutic drugs may be accompanied by both drug resistance and serious side effects in patients. Therefore, safer and more effective medications are urgently needed for the treatment of NSCLC. This study investigates the mode of action of 21 phytoconstituents previously isolated from the Amaryllidaceous plants Crinum bulbispermum (Burm.f.), Pancratium maritimum L., and Hippeastrum vittatum Herbert alongside the Asteraceous plant Centaurea scoparia Sieb. for therapy of NSCLC via
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Dissertations / Theses on the topic "Alpha -lycorane"

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Negel, A. "Conceptually new approach to the total synthesis of (-)-lycorine and (-)-ɣ-lycorane". Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2017. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3921.

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