Academic literature on the topic 'Alstonine'

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Journal articles on the topic "Alstonine"

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Linck, Viviane M., Ana P. Herrmann, Ângelo L. Piato, et al. "Alstonine as an Antipsychotic: Effects on Brain Amines and Metabolic Changes." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–7. http://dx.doi.org/10.1093/ecam/nep002.

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Managing schizophrenia has never been a trivial matter. Furthermore, while classical antipsychotics induce extrapyramidal side effects and hyperprolactinaemia, atypical antipsychotics lead to diabetes, hyperlipidaemia, and weight gain. Moreover, even with newer drugs, a sizable proportion of patients do not show significant improvement. Alstonine is an indole alkaloid identified as the major component of a plant-based remedy used in Nigeria to treat the mentally ill. Alstonine presents a clear antipsychotic profile in rodents, apparently with differential effects in distinct dopaminergic pathw
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Elisabetsky, E., and L. Costa-Campos. "The Alkaloid Alstonine: A Review of Its Pharmacological Properties." Evidence-Based Complementary and Alternative Medicine 3, no. 1 (2006): 39–48. http://dx.doi.org/10.1093/ecam/nek011.

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Indole compounds, related to the metabolism of tryptophan, constitute an extensive family, and are found in bacteria, plants and animals. Indolic compounds possess significant and complex physiological roles, and especially indole alkaloids have historically constituted a class of major importance in the development of new plant derived drugs. The indole alkaloid alstonine has been identified as the major component of a plant-based remedy, used in Nigeria to treat mental illnesses by traditional psychiatrists. Although it is certainly difficult to compare the very concept of mental disorders i
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Costa-Campos, L., D. R. Lara, D. S. Nunes, and E. Elisabetsky. "Antipsychotic-Like Profile of Alstonine." Pharmacology Biochemistry and Behavior 60, no. 1 (1998): 133–41. http://dx.doi.org/10.1016/s0091-3057(97)00594-7.

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Costa-Campos, L., S. C. Dassoler, A. P. Rigo, M. Iwu, and E. Elisabetsky. "Anxiolytic properties of the antipsychotic alkaloid alstonine." Pharmacology Biochemistry and Behavior 77, no. 3 (2004): 481–89. http://dx.doi.org/10.1016/j.pbb.2003.12.002.

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Olawale, Femi, Tomi Lois Adetunji, Ademola Emmanuel Adetunji, Opeyemi Iwaloye, and Ibukun Mary Folorunso. "The therapeutic value of alstonine: An updated review." South African Journal of Botany 152 (January 2023): 288–95. http://dx.doi.org/10.1016/j.sajb.2022.11.047.

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Arnold, M. S. J., J. R. Macdonald, R. J. Quinn, T. S. Skinner-Adams, K. T. Andrews, and G. M. Fisher. "Antiplasmodial activity of the natural product compounds alstonine and himbeline." International Journal for Parasitology: Drugs and Drug Resistance 16 (August 2021): 17–22. http://dx.doi.org/10.1016/j.ijpddr.2021.04.003.

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de Moura Linck, Viviane, Ana Paula Herrmann, Greice Catrine Goerck, et al. "The putative antipsychotic alstonine reverses social interaction withdrawal in mice." Progress in Neuro-Psychopharmacology and Biological Psychiatry 32, no. 6 (2008): 1449–52. http://dx.doi.org/10.1016/j.pnpbp.2008.04.013.

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Costa-Campos, Luciane, Maurice Iwu, and Elaine Elisabetsky. "Lack of pro-convulsant activity of the antipsychotic alkaloid alstonine." Journal of Ethnopharmacology 93, no. 2-3 (2004): 307–10. http://dx.doi.org/10.1016/j.jep.2004.03.056.

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Costa-Campos, L., E. Elisabetsky, D. R. Lara, et al. "ANTIPSYCHOTIC PROFILE OF ALSTONINE: ETHNOPHARMACOLOGY OF A TRADITIONAL NIGERIAN BOTANICAL REMEDY." Acta Horticulturae, no. 501 (February 1999): 313–22. http://dx.doi.org/10.17660/actahortic.1999.501.49.

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Linck, V. M., A. P. Herrmann, M. M. Bessa, C. O. Okunji, M. Iwu, and E. Elisabetsky. "HT2A/C receptors mediate the effects of the putative antipsychotic alstonine." International Clinical Psychopharmacology 26 (September 2011): e167. http://dx.doi.org/10.1097/01.yic.0000405928.87145.dc.

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Dissertations / Theses on the topic "Alstonine"

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Linck, Viviane de Moura. "Perfil antipsicótico de alstonina : ação em modelos de sintomas negativos, alterações em aminas biogênicas e efeitos adversos em camundongos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/13097.

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A esquizofrenia é um transtorno psiquiátrico grave, caracterizado por distúrbios do pensamento, prejuízo da lógica, alterações cognitivas e emocionais, e/ou isolamento social. Apesar da introdução de novos antipsicóticos, um grupo considerável de pacientes ainda é refratário aos tratamentos disponíveis. Além disso, a alta incidência de efeitos adversos leva à baixa adesão ao tratamento em esquizofrênicos. O desenvolvimento de tratamentos mais eficazes e com menor incidência de efeitos adversos, que aumentem a adesão ao tratamento e melhorem a qualidade de vida destes pacientes, é assim altamen
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Arnold, Megan. "Investigating natural products as new drug leads for malaria." Thesis, Griffith University, 2018. http://hdl.handle.net/10072/381398.

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Despite being preventable and treatable, malaria continues to be a significant threat to global health, particularly in the developing world. It is estimated that 90% of all malaria deaths occur in Africa and that 78% of these deaths occur in children under five years of age due to infection with Plasmodium falciparum malaria parasites. While malaria control strategies, together with the global malaria eradication agenda, has resulted in a 48% decline in global malaria mortality rates over the past decade, progress has stalled. A recent rise in malaria cases is particularly concerning given th
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Linck, Viviane de Moura. "Modulação de vias serotonérgicas e dopaminérgicas por alstonina : possível inovação no mecanismo de ação de antipsicóticos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/142804.

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Ainda que descrita pela primeira vez em 1893 por Emil Kraepelin, a esquizofrenia continua sendo uma doença mental extremamente debilitante e de difícil tratamento. A introdução dos antipsicóticos típicos na década de 50 e dos atípicos na década de 90 mudou consideravelmente a realidade dos esquizofrênicos, no entanto a baixa eficácia (principalmente quanto aos sintomas negativos e cognitivos) associada a alta incidência de efeitos adversos requer inovação na farmacodinâmica de antipsicóticos. Alstonina, um alcaloide indólico, é o componente majoritário de uma preparação utilizada para tratar p
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Rahn, Volker Siegfried. "Synthetic studies towards the total synthesis of (-)-alstonerine." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401724.

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Pett, Richard. "Total synthesis of the macroline-related alkaloid (±)-alstonerine." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/17842.

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This thesis examines the total synthesis of the macroline-related indole alkaloid alstonerine and related compounds. It is divided into three sections: The first section provides a review of the total synthesis efforts reported by Cook, Martin, Kuethe, and Kwon, as well previous work within the Craig group. The second section discusses the results of our investigations. The optimisation of the synthesis of key intermediate α,β-unsaturated lactam alcohol via directed-aziridine ring-opening is presented in detail. Our progress towards the synthesis of macroline-related alkaloids macroline, alsto
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Nkiliza, Jean. "Synthèse totale de la 19-hydroxytubotaïwine et préparation d'indoloazépines de type Iboga." Bordeaux 2, 1990. http://www.theses.fr/1990BOR2B002.

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Keawpradub, Niwat. "Studies on the bioactivity and alkaloids of three Thai alstonia species." Thesis, King's College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286253.

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Hundley, Nicholas James. "Structure Elucidation of Bioactive Compounds Isolated from Endophytes of Alstonia scholaris and Acmena graveolens." Diss., CLICK HERE for online access, 2005. http://contentdm.lib.byu.edu/ETD/image/etd1013.pdf.

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Mesbah, Khaled. "Alcaloides de quatre especes de la famille des apocynaceae : vallesia glabra, aspidosperma macrocarpon, alstonia brassii et peschiera benthamiana (doctorat : pharmacognosie)." Reims, 1997. http://www.theses.fr/1997REIMP205.

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Ahamada, Kadiria. "Stratégies biomimétiques en vue de la synthèse totale de deux substances naturelles polycycliques complexes : la bipléiophylline et l'haliclonine A." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA114807/document.

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Les travaux présentés concernent dans une première partie la synthèse biomimétique d’un alcaloïde indolomonoterpénique : la bipléiophylline. La bipléiophylline est le résultat de l’assemblage complexe de deux unités indoliques identiques ancrées sur une plateforme aromatique. Une stratégie générale de synthèse biomimétique de la bipléiophylline consistant i) à la synthèse de l’unité indolique pléiocarpamine et ii) à l’oxydation de l’acide 2,3-dihydroxybenzoïque a été envisagée. L’accès au squelette complexe de la pléiocarpamine a été étudié selon plusieurs stratégies de synthèse totale mais ég
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Books on the topic "Alstonine"

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Taxonomy, phylogeny, and wood anatomy of Alstonia (Apocynaceae). Rijksherbarium/Hortus Botanicus, Leiden University, 1998.

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Book chapters on the topic "Alstonine"

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Omino, E. A. "Alstonia." In Flora of Tropical East Africa. CRC Press, 2022. http://dx.doi.org/10.1201/9781003211358-18.

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Khare, C. P. "Alstonia scholaris R. Br." In Indian Medicinal Plants. Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_92.

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Khare, C. P. "Alstonia venenata R. Br." In Indian Medicinal Plants. Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_93.

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Akbar, Shahid. "Alstonia scholaris (L.) R.Br. (Apocynaceae)." In Handbook of 200 Medicinal Plants. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-16807-0_21.

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Bhatt, Man D., Ripu M. Kunwar, Basnyat Bijendra, Rainer W. Bussmann, and Narel Y. Paniagua-Zambrana. "Alstonia scholaris (L.) R. Br. Apocynaceae." In Ethnobotany of the Himalayas. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-45597-2_17-1.

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Bhatt, Man D., Ripu M. Kunwar, Bijendra Basnyat, Rainer W. Bussmann, and Narel Y. Paniagua-Zambrana. "Alstonia scholaris (L.) R. Br. Apocynaceae." In Ethnobotany of the Himalayas. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57408-6_17.

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Bhatt, Man D., Ripu M. Kunwar, Bijendra Basnyat, Rainer W. Bussmann, and Narel Y. Paniagua-Zambrana. "Alstonia scholaris (L.) R. Br. Apocynaceae." In Ethnobotany of the Himalayas. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-45597-2_17-2.

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Paul, Atish T., Ginson George, Nisha Yadav, Arjun Jeswani, and Prashant S. Auti. "Pharmaceutical Application of Bio-actives from Alstonia Genus: Current Findings and Future Directions." In Advanced Structured Materials. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-54027-2_14.

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Pratiwi, Erna Hasani Kusuma, Sri Idawati, Sri Rahmawati, et al. "Activity Test of Ethanol Extract from Pulai Bark (Alstonia scholaris L.) Antiinflammation in Mice (Mus musculus)." In Proceedings of the First International Conference on Medical Technology (ICoMTech 2021). Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-018-3_15.

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Jain, Rahul, S. Chaurasia, R. C. Saxena, and D. K. Jain. "Identification of Flavonoids in The Bark of Alstonia Scholaris by High Performance Liquid Chromatography- Electrospray Mass Spectrometry." In Chemistry of Phytopotentials: Health, Energy and Environmental Perspectives. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-23394-4_14.

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Conference papers on the topic "Alstonine"

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Viallet, Pierre M., Tuan Vo-Dinh, Jean-Marie Salmon, et al. "Alstonine as a potential fluorescent marker for tiny tumor detection and imaging." In BiOS '97, Part of Photonics West, edited by Tuan Vo-Dinh, Robert A. Lieberman, Gerald G. Vurek, and Abraham Katzir. SPIE, 1997. http://dx.doi.org/10.1117/12.275541.

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Rahim, Nurhidayah Ab, Noorzafiza Zakaria, Syarifah Masyitah Habib Dzulkarnain, Nazar Mohd Zabadi Mohd Azahar, and Mahmood Ameen Abdulla. "Antioxidant activity of alstonia Angustifolia ethanolic leaf extract." In THE 2ND INTERNATIONAL CONFERENCE ON APPLIED SCIENCE AND TECHNOLOGY 2017 (ICAST’17). Author(s), 2017. http://dx.doi.org/10.1063/1.5005345.

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Balipa, Mamatha, and Ashton Castalino. "Alstonia Tree Detection using CNN and Inception V3 Algorithms." In 2022 International Conference on Computing, Communication, and Intelligent Systems (ICCCIS). IEEE, 2022. http://dx.doi.org/10.1109/icccis56430.2022.10037697.

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Greiffer, L., V. Spiegler, J. Jacobtorweihen, and A. Hensel. "Zytotoxische Effekte eines traditionell verwendeten Extraktes aus Alstonia-boonei-Blättern." In Phytotherapiekongress 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1697300.

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MAWAZIN, MAWAZIN. "Pertumbuhan tanaman pulai (Alstonia scholaris) pada lahan bekas tambang batubara di Kalimantan Timur." In Seminar Nasional Masyarakat Biodiversitas Indonesia. Masyarakat Biodiversitas Indonesia, 2016. http://dx.doi.org/10.13057/psnmbi/m020220.

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Spiegler, V., R. Börner, M. Grimm, L. Greiffer, and J. Jacobtorweihen. "Cytotoxic activities of 15-hydroxyangustilobine A, a major indole alkaloid from the leaves of Alstonia boonei." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759244.

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Gunawan, Endra, Edy Budiarso, Enih Rosamah, and Enos Tangke Arung. "Preservation of Pulai Wood (Alstonia scolaris L. Br.) with Natural Preservative Fruit Extracts Orania palindan (Blanco) Merr." In Joint Symposium on Tropical Studies (JSTS-19). Atlantis Press, 2021. http://dx.doi.org/10.2991/absr.k.210408.018.

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Hamdiani, S., M. Al-As’ari, A. R. Satriani, and S. Hadi. "Alkaloids from Pulai (Alstonia scholaris (L.) R. Br.) leaves of Lombok Island on the basis of GC-MS analysis." In PROCEEDINGS OF THE 3RD INTERNATIONAL SYMPOSIUM ON CURRENT PROGRESS IN MATHEMATICS AND SCIENCES 2017 (ISCPMS2017). Author(s), 2018. http://dx.doi.org/10.1063/1.5064088.

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